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https://www.readbyqxmd.com/read/29763648/autism-spectrum-disorder-classification-diagnosis-and-therapy
#1
REVIEW
Samata R Sharma, Xenia Gonda, Frank I Tarazi
Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not otherwise specified (PDD-NOS). The new diagnostic criteria of ASD focuses on two core domains: social communication impairment and restricted interests/repetitive behaviors. The prevalence of ASD has been steadily increasing over the past two decades, with current estimates reaching up to 1 in 36 children. Hereditary factors, parental history of psychiatric disorders, pre-term births, and fetal exposure to psychotropic drugs or insecticides have all been linked to higher risk of ASD...
May 12, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29742331/youth-with-autism-spectrum-disorder-in-the-emergency-department
#2
Sarah Lytle, Andrew Hunt, Sonal Moratschek, Marcie Hall-Mennes, Martha Sajatovic
OBJECTIVE: This comprehensive literature review summarizes reports on emergency department (ED) use by youth with autism spectrum disorder (ASD). DATA SOURCES: We conducted a systematic search of the PubMed, PsycINFO, CINAHL, and EMBASE databases (1985-2016), limited to studies published in English. The following search terms were used: autism, autistic, Asperger, emergency department/room/physician/doctor/treatment/medicine, childhood developmental disorders (pervasive), and emergencies...
May 8, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29740126/the-truth-about-hans-asperger-s-nazi-collusion
#3
Simon Baron-Cohen
No abstract text is available yet for this article.
May 2018: Nature
https://www.readbyqxmd.com/read/29713442/hans-asperger-national-socialism-and-race-hygiene-in-nazi-era-vienna
#4
Herwig Czech
Background: Hans Asperger (1906-1980) first designated a group of children with distinct psychological characteristics as 'autistic psychopaths' in 1938, several years before Leo Kanner's famous 1943 paper on autism. In 1944, Asperger published a comprehensive study on the topic (submitted to Vienna University in 1942 as his postdoctoral thesis), which would only find international acknowledgement in the 1980s. From then on, the eponym 'Asperger's syndrome' increasingly gained currency in recognition of his outstanding contribution to the conceptualization of the condition...
2018: Molecular Autism
https://www.readbyqxmd.com/read/29713441/did-hans-asperger-actively-assist-the-nazi-euthanasia-program
#5
EDITORIAL
Simon Baron-Cohen, Ami Klin, Steve Silberman, Joseph D Buxbaum
No abstract text is available yet for this article.
2018: Molecular Autism
https://www.readbyqxmd.com/read/29701730/prevalence-of-autism-spectrum-disorder-among-children-aged-8-years-autism-and-developmental-disabilities-monitoring-network-11-sites-united-states-2014
#6
Jon Baio, Lisa Wiggins, Deborah L Christensen, Matthew J Maenner, Julie Daniels, Zachary Warren, Margaret Kurzius-Spencer, Walter Zahorodny, Cordelia Robinson Rosenberg, Tiffany White, Maureen S Durkin, Pamela Imm, Loizos Nikolaou, Marshalyn Yeargin-Allsopp, Li-Ching Lee, Rebecca Harrington, Maya Lopez, Robert T Fitzgerald, Amy Hewitt, Sydney Pettygrove, John N Constantino, Alison Vehorn, Josephine Shenouda, Jennifer Hall-Lande, Kim Van Naarden Braun, Nicole F Dowling
PROBLEM/CONDITION: Autism spectrum disorder (ASD). PERIOD COVERED: 2014. DESCRIPTION OF SYSTEM: The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance system that provides estimates of the prevalence of autism spectrum disorder (ASD) among children aged 8 years whose parents or guardians reside within 11 ADDM sites in the United States (Arizona, Arkansas, Colorado, Georgia, Maryland, Minnesota, Missouri, New Jersey, North Carolina, Tennessee, and Wisconsin)...
April 27, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29695940/camus-s-l-%C3%A3-tranger-and-the-first-description-of-a-man-with-asperger-s-syndrome
#7
Sam Shuster
The continued discussion about the meaning of Camus's famous novel, L'étranger , provoked a re-reading, and this, in turn, led to its clinical analysis and further investigation. The book rests entirely on the thoughts, words and actions of its central character, Meursault, and these were found to show impairment of social relationships, communication and interaction, with other traits diagnostic of the Asperger's subgroup of the autism spectrum disorder. It was then found that Camus had based Meursault on his close friend Galindo, and a search was therefore made for evidence of Galindo's character; this revealed him to be an intelligent but odd person, who exhibited the characteristic impairment of social and personal behavior of Asperger's syndrome...
2018: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/29694960/kynurenine-pathway-in-autism-spectrum-disorders-in-children
#8
Vesna Bryn, Robert Verkerk, Ola H Skjeldal, Ola Didrik Saugstad, Heidi Ormstad
BACKGROUND: There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory states, we aimed to determine whether this pathway is activated in ASD. METHODS: Sixty-five pediatric ASD patients (including 52 boys) were enrolled from an epidemiological survey covering 2 counties in Norway; 30 (46...
April 25, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29682383/polysubstance-and-behavioral-addictions-in-a-patient-with-bipolar-disorder-role-of-lifetime-subthreshold-autism-spectrum
#9
Liliana Dell'Osso, Ciro Conversano, Martina Corsi, Carlo A Bertelloni, Ivan M Cremone, Barbara Carpita, Manuel G Carbone, Camilla Gesi, Claudia Carmassi
This case report draws attention to the potential relevance of undetected autism spectrum symptoms in a bipolar patient with high work functioning showing a peculiar addictive profile with impulsive and antisocial behaviors. A 23-year-old man with a diagnosis of Bipolar Disorder (BD) and Substance Use Disorder (SUD) was hospitalized at the Psychiatric Clinic of the University of Pisa for diuretics and β -2 adrenergic agonist abuse in a remission phase of benzodiazepines and substance abuse. He reported a history of behavioral addictions in the framework of a global high work functioning with particular skills in computer science...
2018: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/29666039/comment-on-olanzapine-induced-priapism-in-a-child-with-asperger-s-syndrome
#10
Mete Özkıdık, Anar İbrahimov
No abstract text is available yet for this article.
April 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29628271/functional-network-abnormalities-consistent-with-behavioral-profile-in-autism-spectrum-disorder
#11
René Besseling, Rolf Lamerichs, Britt Michels, Stephan Heunis, Anton de Louw, Anton Tijhuis, Jan Bergmans, Bert Aldenkamp
Autism spectrum disorder (ASD) is a neurodevelopmental disorder in which the severity of symptoms varies over subjects. The iCAPs model (innovation-driven co-activation patterns) is a recently developed spatio-temporal model to describe fMRI data. In this study, the iCAPs model was employed to find functional imaging biomarkers for ASD in resting-state fMRI data. MRI data from 125 ASD patients and 243 healthy controls was selected from the online ABIDE data repository. Following standard fMRI preprocessing steps, the iCAP patterns were fitted to the data to obtain network time series...
February 21, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29546821/-asperger-syndrome-and-or-clinical-high-risk-of-psychosis-a-differential-diagnostic-challenge
#12
Stefanie J Schmidt, Ayla Behar, Frauke Schultze-Lutter
Asperger Syndrome and/or Clinical High Risk of Psychosis? A Differential Diagnostic Challenge This case-study deals with the often difficult differential diagnosis of Asperger syndrome and a clinical high risk state of psychosis, in particular as indicated by attenuated psychotic symptoms, as well as with its therapeutic implications. The presented case is a 10-year old girl, who has not been diagnosed with an autism spectrum disorder before being referred to a specialized center for early detection of psychosis due to possible hallucinatory experiences and delusional ideas...
March 2018: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/29516452/-perisylvian-magnetoencephalografic-impairments-in-patients-with-autism-spectrum-disorders
#13
M Palau-Baduell, B Salvado-Salvado, M A Idiazabal-Alecha, A Fernandez-Teruel, T Ortiz
INTRODUCTION: The perisylvian areas, located around the Sylvian fissure, are constituted by frontal, temporal and parietal brain regions. These are connected forming specialized neural networks and play a primary role in the development of linguistic skills and social cognition. These areas are a possible neuronal substrate of cognitive and behavioral impairments in patients with autism spectrum disorders (ASD). AIM: To locate and quantify epileptiform activity sources through magnetoencephalography in frontal perisylvian areas in children with idiopathic ASD...
March 1, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29477010/impaired-detection-and-differentiation-of-briefly-presented-facial-emotions-in-adults-with-high-functioning-autism-and-asperger-syndrome
#14
R Frank, L Schulze, R Hellweg, S Koehne, S Roepke
Although deficits in the recognition of emotional facial expressions are considered a hallmark of autism spectrum disorder (ASD), characterization of abnormalities in the differentiation of emotional expressions (e.g., sad vs. angry) has been rather inconsistent, especially in adults without intellectual impairments who may compensate for their deficits. In addition, previous research neglected the ability to detect emotional expressions (e.g., angry vs. neutral). The present study used a backward masking paradigm to investigate, a) the detection of emotional expressions, and b) the differentiation of emotional expressions in adults diagnosed with high functioning autism or Asperger syndrome (n = 23) compared to neurotypical controls (n = 25)...
May 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29427542/school-dysfunction-in-youth-with-autistic-spectrum-disorder-in-taiwan-the-effect-of-subtype-and-adhd
#15
Huey-Ling Chiang, Wei-Chih Kao, Mei-Chun Chou, Wen-June Chou, Yen-Nan Chiu, Yu-Yu Wu, Susan Shur-Fen Gau
School dysfunction is observed in youths with autism spectrum disorder (ASD), but the factors moderating their school dysfunction have not been well explored. This study investigated school functions in youths with ASD in Taiwan, stratified by personal characteristics including demographics, ASD subtypes, intelligence profiles, and the presence of attention-deficit hyperactivity disorder (ADHD). We recruited 160 youths (aged 6-18 years, 87.5% boys) with a clinical diagnosis of ASD and 160 age and gender-matched typically developing (TD) youths...
February 10, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29427532/a-pilot-study-of-high-dose-intravenous-immunoglobulin-5-for-autism-impact-on-autism-spectrum-and-markers-of-neuroinflammation
#16
Isaac R Melamed, Melinda Heffron, Alessandro Testori, Kellie Lipe
Research has shown that a subset of the autism spectrum disorder (ASD) population presents with immune dysregulation. To explore this topic further, we investigated the efficacy and tolerability of intravenous immunoglobulin (IVIG) infusion in children with ASD. In this study, participants were recruited based on a diagnosis of autistic disorder, Asperger's disorder, or pervasive developmental disorder not otherwise specified. Participants also showed evidence of immune dysfunction based on abnormal levels of specific biomarkers, including CD40 ligand (CD154), lymphocyte stimulation, and T or B cell dysfunction...
March 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29423607/brief-report-social-functioning-predicts-externalizing-problem-behaviors-in-autism-spectrum-disorder
#17
N Shea, E Payne, N Russo
Individuals with ASD often display externalizing behaviors, which have been associated with lower quality of life in adulthood. Social difficulties have been hypothesized to underlie externalizing problems among individuals with ASD (Klin and Volkmar in Asperger Syndrome, 340-366, 2000), but this has never been tested empirically. We examined whether socialization abilities predicted externalizing problems assessed by parent report in a group of 29 individuals with ASD (age range 7-16 years) and 29 TD individuals matched for IQ, age, and gender...
February 8, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29400401/emotional-preferences-and-goals-and-emotion-dysregulation-in-children-with-asperger-s-syndrome-and-typically-developing-children
#18
Belén López-Pérez, Tamara Ambrona, Michaela Gummerum
OBJECTIVES: Emotion goals lie at the heart of emotion regulation, as people have to first decide what emotions they want to feel before engaging in emotion regulation. Given that children with Asperger's syndrome (AS) are characterized by exhibiting difficulties in emotion regulation, studying whether they display similar or different emotion goals compared to typically developing (TD) children may provide insightful information. METHODS: Thirty AS and 30 TD children (10-12 years) reported about their general (i...
February 5, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29283066/herbal-medicine-as-an-alternative-treatment-in-autism-spectrum-disorder-a-systematic-review
#19
Francielly Mourao Gasparotto, Francislaine Aparecida Liveror, Sara Emilia Lima Tolouei Menegati, Arquimedes Gasparotto Junior
This review focuses on the efficacy and safety of herbal medicines in the management of autism spectrum disorder (ASD) in humans and animals. PubMed, Scopus, Google Scholar, Web of Science, and Science Direct databases were searched up to October 30, 2016. The key terms used were "ASD", "Asperger", "autism", "healing plants", "herbal medicine", and "medicinal plants". In each database, the searches consisted of each of the three key terms describing the disorder and subtypes plus each of the terms describing the therapy...
December 27, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/29244813/a-different-view-on-the-necker-cube-differences-in-multistable-perception-dynamics-between-asperger-and-non-asperger-observers
#20
Jürgen Kornmeier, Rike Wörner, Andreas Riedel, Ludger Tebartz van Elst
BACKGROUND: During observation of the Necker cube perception becomes unstable and alternates repeatedly between a from-above-perspective ("fap") and a from-below-perspective ("fbp") interpretation. Both interpretations are physically equally plausible, however, observers usually show an a priori top-down bias in favor of the fap interpretation. Patients with Autism spectrum disorder are known to show an altered pattern of perception with a focus on sensory details...
2017: PloS One
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