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https://www.readbyqxmd.com/read/28972697/feasibility-of-sustained-low-efficiency-dialysis-in-critically-sick-pediatric-patients-a-multicentric-retrospective-study
#1
Sidharth K Sethi, Rajiv Sinha, Pranaw Jha, Nikita Wadhwani, Veena Raghunathan, Maninder Dhaliwal, Shyam B Bansal, Vijay Kher, Valentine Lobo, Jyoti Sharma, Rupesh Raina
INTRODUCTION: Sustained low-efficiency dialysis (SLED) has emerged as a cost effective alternative to Continuous Renal Replacement Therapy in the management of hemodynamically unstable adult patients with acute kidney injury. The objective of the study was to document the SLED practices in these centers, and to look at the feasibility, and tolerability of SLED in critically sick pediatric patients. METHODS: It was a retrospective record review from January 2010 to June 2016 done in four tertiary pediatric nephrology centers in India...
October 3, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28962695/arterio-venous-fetoplacental-vascular-geometry-and-hemodynamics-in-the-mouse-placenta
#2
Monique Y Rennie, Lindsay S Cahill, S Lee Adamson, John G Sled
INTRODUCTION: The fetoplacental vasculature network is essential for the exchange of nutrients, gases and wastes with the maternal circulation and for normal fetal development. The present study quantitatively compares arterial and venous morphological and functional differences in the mouse fetoplacental vascular network. METHODS: High resolution X-ray micro-computed tomography was used to visualize the 3D geometry of the arterial and venous fetoplacental vasculature in embryonic day 15...
October 2017: Placenta
https://www.readbyqxmd.com/read/28945690/epidemiology-of-anterior-tibial-spine-fractures-in-young-patients-a-retrospective-cohort-study-of-122-cases
#3
Derek P Axibal, Justin J Mitchell, Meredith H Mayo, Jorge Chahla, Chase S Dean, Claire E Palmer, Kristen Campbell, Armando F Vidal, Jason T Rhodes
BACKGROUND: Historically, bicycle accidents were described as the most common mechanism for pediatric anterior tibial spine fractures (ATSFs). There is a paucity of current literature examining the demographic factors associated with these injuries. The purpose of this cohort study was to characterize the epidemiology of ATSFs presenting to a single tertiary referral pediatric hospital. METHODS: A consecutive cohort of 122 pediatric patients with ATSFs between 1996 and 2014 were reviewed...
September 22, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28944722/is-strength-training-frequency-a-key-factor-to-develop-performance-adaptations-in-young-elite-soccer-players
#4
Carlos Otero-Esquina, Moisés de Hoyo Lora, Óliver Gonzalo-Skok, Sergio Domínguez-Cobo, Hugo Sánchez
The aim of this study was to analyse the effects of a combined strength-training programme (full-back squat, YoYo(TM) leg curl, plyometrics and sled towing exercises) on performance in elite young soccer players and to examine the effects when this training programme was performed one or two days per week. Thirty-six male soccer players (U-17 to U-19) were recruited and assigned to experimental groups (EXP1: 1 s w(-1); EXP2: 2 s w(-1)) or a control group (CON). Performance was assessed through a countermovement jump (CMJ) test (relative peak power [CMJPP] and CMJ height [CMJH]), a 20-m linear sprint test with split-times at 10-m, and a change of direction test (V-cut test) 1 week before starting the training programme and also 1 week after performing such training programme...
September 24, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28937917/head-impact-exposure-measured-in-a-single-youth-football-team-during-practice-drills
#5
Mireille E Kelley, Joeline M Kane, Mark A Espeland, Logan E Miller, Alexander K Powers, Joel D Stitzel, Jillian E Urban
OBJECTIVE This study evaluated the frequency, magnitude, and location of head impacts in practice drills within a youth football team to determine how head impact exposure varies among different types of drills. METHODS On-field head impact data were collected from athletes participating in a youth football team for a single season. Each athlete wore a helmet instrumented with a Head Impact Telemetry (HIT) System head acceleration measurement device during all preseason, regular season, and playoff practices...
September 12, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28930879/repeat-effort-performance-is-reduced-24-h-following-acute-dehydration-in-mixed-martial-arts-athletes
#6
Oliver R Barley, Fiona Iredale, Dale W Chapman, Amanda Hopper, Chris Abbiss
This study sought to determine the influence of acute dehydration on physical performance and physiology in Mixed Martial Arts (MMA). MMA athletes (n=14; age: 23±4 years), completed in a randomised counterbalanced order a dehydration protocol, (DHY: 3 h cycling at 60 W in 40°C to induce 5% dehydration) or thermoneutral control (25°C: CONT) exercise, followed by ad libitum fluid/food intake. Performance testing (a repeat sled push test, medicine ball chest throw and vertical jump) was completed 3 and 24 h following the intervention, while urine and blood samples were collected before, 20 min, 3 and 24 h following the intervention...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28902107/reliability-of-the-maximal-resisted-sprint-load-test-and-relationships-with-performance-measures-and-anthropometric-profile-in-female-field-sport-athletes
#7
George Petrakos, Nicola C Tynan, Adam M Vallely-Farrell, Cillian Kiely, Abdelhak Boudhar, Brendan Egan
Resisted sled sprint (RSS) training is an effective modality for the improvement of linear sprint speed. Previous methods of RSS load prescription e.g. an absolute load or as a percentage of body mass (%BM), do not account for inter-individual differences in strength, power or speed characteristics, although the 'maximum resisted sled load' (MRSL) method of RSS load prescription may provide a solution. MRSL is defined as the final RSS load before an athlete can no longer accelerate between two phases (10-15 m and 15-20 m) of a 20 m linear sprint...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28872389/training-related-changes-in-force-power-profiles-implications-for-the-skeleton-start
#8
Steffi L Colyer, Keith A Stokes, James L J Bilzon, Danny Holdcroft, Aki I T Salo
PURPOSE: Athletes' force-power characteristics influence sled velocity during the skeleton start, which is a crucial determinant of performance. This study characterised force-power profile changes across an 18-month period and investigated the associations between these changes and start performance. METHODS: Seven elite- and five talent-squad skeleton athletes' (representing 80% of registered athletes in the country) force-power profiles and dry-land push-track performances were assessed at multiple time-points over two 6-month training periods and one 5-month competition season...
September 5, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28861917/feto-and-utero-placental-vascular-adaptations-to-chronic-maternal-hypoxia-in-the-mouse
#9
Lindsay S Cahill, Monique Y Rennie, Johnathan Hoggarth, Lisa X Yu, Anum Rahman, John C Kingdom, Mike Seed, Christopher K Macgowan, John G Sled
KEY POINTS: Chronic fetal hypoxia is one of the most common complications of pregnancy and is known to cause fetal growth restriction. The structural adaptations of the placental vasculature responsible for growth restriction with chronic hypoxia are not well elucidated. Using a mouse model of chronic maternal hypoxia in combination with micro-computed tomography and scanning electron microscopy, we found several placental adaptations that were beneficial to fetal growth including capillary expansion, thinning of the interhaemal membrane and increased radial artery diameters, resulting in a large drop in total utero-placental vascular resistance...
September 1, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28813547/an-experimental-and-numerical-study-of-hybrid-iii-dummy-response-to-simulated-underbody-blast-impacts
#10
Karthik Somasundaram, Anil Kalra, Don Sherman, Paul Begeman, King H Yang, John Cavanaugh
Anthropometric test devices (ATDs) such as the Hybrid III dummy have been widely used in automotive crash tests to evaluate the risks of injury at different body regions. In recent years, researchers have started using automotive ATDs to study the high-speed vertical loading response caused by underbody blast impacts. This study analyzed the Hybrid III dummy responses to short-duration, large magnitude vertical accelerations in a laboratory setup. Two unique test conditions were investigated using a horizontal sled system to simulate underbody blast loading conditions...
December 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28812394/the-use-of-sustained-low-efficiency-dialysis-sled-in-massive-paracetamol-overdose
#11
Anselm Wong, Roger L K Tong, Liam Ryan, Tim Crozier, Andis Graudins
CONTEXT: Massive paracetamol ingestion causing mitochondrial dysfunction is uncommon. Use of sustained low-efficiency dialysis (SLED) to improve acidaemia and enhance paracetamol elimination has not been previously described. CASE DETAILS: A 44-year-old male presented to the emergency department 2.5 hours post overdose of 200 g (2.5 g/kg) of paracetamol. Examination revealed a BP 85/60 mmHg, pulse 112 bpm, temperature 33.9 °C and blood glucose of 13...
August 16, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28794456/activated-nk-cells-cause-placental-dysfunction-and-miscarriages-in-fetal-alloimmune-thrombocytopenia
#12
Issaka Yougbaré, Wei-She Tai, Darko Zdravic, Brigitta Elaine Oswald, Sean Lang, Guangheng Zhu, Howard Leong-Poi, Dawei Qu, Lisa Yu, Caroline Dunk, Jianhong Zhang, John G Sled, Stephen J Lye, Jelena Brkić, Chun Peng, Petter Höglund, B Anne Croy, S Lee Adamson, Xiao-Yan Wen, Duncan J Stewart, John Freedman, Heyu Ni
Miscarriage and intrauterine growth restriction (IUGR) are devastating complications in fetal/neonatal alloimmune thrombocytopenia (FNAIT). We previously reported the mechanisms for bleeding diatheses, but it is unknown whether placental, decidual immune cells or other abnormalities at the maternal-fetal interface contribute to FNAIT. Here we show that maternal immune responses to fetal platelet antigens cause miscarriage and IUGR that are associated with vascular and immune pathologies in murine FNAIT models...
August 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28724961/coherence-properties-of-different-light-sources-and-their-effect-on-the-image-sharpness-and-speckle-of-holographic-displays
#13
Yuanbo Deng, Daping Chu
Coherence properties of different light sources and how they affect the image quality of holographic display are investigated. Temporal coherence is related to the intrinsic spectrum bandwidth of the light source, while spatial coherence can be affected by the size of the light source and propagation distance in use. These two coherence properties are measured for various light sources of diode-pumped solid-state (DPSS) laser, laser diode (LD), light emitting diode (LED), super luminescent light emitting diode (sLED) and micro light emitting diode (mLED) in different settings, together with the quality of the holographic reconstructed images...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28719778/medial-malleoli-fractures-clinical-comparison-between-newly-designed-sled-device-and-conventional-screws
#14
Hemil Maniar, Harish Kempegowda, Akhil A Tawari, Michael R Rutter, Amrut Borade, Gerard Cush, Daniel S Horwitz
BACKGROUND: The Trimed Medial Malleolar Sled is a newer device designed to treat medial malleolus fracture. The purpose of this study was to compare the outcome of medial malleolar fractures treated with the sled and conventional malleolar screws. METHODS: After obtaining an institutional review board approval, we conducted a retrospective study to identify all skeletally mature patients who sustained an ankle fracture with medial malleolar involvement treated with the sled and we identified a matched cohort treated with conventional malleolar screws...
August 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28700513/sled-towing-acutely-decreases-acceleration-sprint-time
#15
Megan A Wong, Ian J Dobbs, Casey M Watkins, Saldiam R Barillas, A Lin, David C Archer, Robert G Lockie, Jared W Coburn, Lee E Brown
Sled towing is a common form of overload training in sports to develop muscular strength for sprinting. This type of training leads to acute and chronic outcomes. Acute training potentially leads to postactivation potentiation (PAP), which is when subsequent muscle performance is enhanced following a preload stimulus. The purpose of this study was to determine differences between rest intervals following sled towing on acute sprint speed. Twenty healthy recreationally trained males (age= 22.3 ± 2.4yrs, height= 176...
July 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28696780/evaluation-of-the-effectiveness-of-toe-board-energy-absorbing-material-for-foot-ankle-and-lower-leg-injury-reduction
#16
John P Patalak, Joel D Stitzel
OBJECTIVE: Since 2000, numerous improvements have been made to the National Association for Stock Car Auto Racing, Incorporated (NASCAR®) driver restraint system, resulting in improved crash protection for motorsports drivers. Advancements have included seats, head and neck restraints (HNRs), seat belt restraint systems, driver helmets, and others. These enhancements have increased protection for drivers from severe crash loading. Extending protection to the driver's extremities remains challenging...
July 11, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28686319/magnetic-resonance-thermometry-of-flowing-blood
#17
Chinthaka C Heyn, Jonathan Bishop, Kyle Duffin, Wayne Lee, Jun Dazai, Shoshana Spring, Brian J Nieman, John G Sled
Blood temperature is a key determinant of tissue temperature and can be altered under normal physiological states, such as exercise, in diseases such as stroke or iatrogenically in therapies which modulate tissue temperature, such as therapeutic hypothermia. Currently available methods for the measurement of arterial and venous temperatures are invasive and, for small animal models, are impractical. Here, we present a methodology for the measurement of intravascular and tissue temperature by magnetic resonance imaging (MRI) using the lanthanide agent TmDOTMA(-) (DOTMA, tetramethyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid; Tm, thulium)...
July 7, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28678610/occupant-responses-in-conventional-and-abts-seats-in-high-speed-rear-sled-tests
#18
David C Viano, Chantal S Parenteau, Roger Burnett, Priya Prasad
OBJECTIVE: This study compared biomechanical responses of a normally seated Hybrid III dummy on conventional and ABTS (all belts to seat) seats in 40.2 km/h (25 mph) rear sled tests. It determined the difference in performance with modern (≥2000 MY) seats compared to older (<2000 MY) seats and ABTS seats. METHODS: The seats were fixed in a sled buck subjected to a 40.2 km/h (25 mph) rear sled test. The pulse was a 15 g double-peak acceleration with 150 ms duration...
July 5, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28632062/skeleton-sled-velocity-profiles-a-novel-approach-to-understand-critical-aspects-of-the-elite-athletes-start-phases
#19
Steffi L Colyer, Keith A Stokes, James L J Bilzon, Aki I T Salo
The development of velocity across the skeleton start is critical to performance, yet poorly understood. We aimed to understand which components of the sled velocity profile determine performance and how physical abilities influence these components. Thirteen well-trained skeleton athletes (>85% of athletes in the country) performed dry-land push-starts alongside countermovement jump and sprint tests at multiple time-points. A magnet encoder attached to the sled wheel provided velocity profiles, which were characterised using novel performance descriptors...
February 28, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28632050/effects-of-turf-and-cleat-footwear-on-plantar-load-distributions-in-adolescent-american-football-players-during-resisted-pushing
#20
Jeffrey B Taylor, Anh-Dung Nguyen, Janet R Griffin, Kevin R Ford
Metatarsal and midfoot injuries are common in American football. Footwear design may influence injury rates by altering plantar foot loading patterns in these regions. The purpose of this study was to determine the effect of cleat design on in-shoe plantar foot loading during a football-specific, resisted pushing task. Twenty competitive football players (age 14.7 ± 1.8 years, height 1.72 ± 0.10 m, and mass 71.8 ± 26.9 kg) completed three trials of pushing a weighted sled at maximal effort in a standard shoe (CLEAT) and artificial turf-specific shoe (TURF), with flexible in-shoe force measuring insoles...
February 28, 2017: Sports Biomechanics
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