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https://www.readbyqxmd.com/read/28211837/the-physiological-demand-of-pulling-a%C3%A2-rescue-sled-across-the-mud-and-the-impact-experience-has-on-this-task
#1
Gemma S Milligan, James R House, Michael J Tipton
BACKGROUND: To establish a Physical Employment Standard for tasks with high physical demands, it is important to determine the physiological requirements. One such task for the UK Coastguard is mud rescue. OBJECTIVE: To quantify the physiological demand of pulling a rescue sled across estuary mud, and determine whether rescuer experience has an impact on the physiological demand of this task. METHODS: Forty participants walked 150 m in 3 minutes across estuary mud...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28191646/non-invasive-evaluation-of-blood-oxygen-saturation-and-hematocrit-from-t1-and-t2-relaxation-times-in-vitro-validation-in-fetal-blood
#2
Sharon Portnoy, Mike Seed, John G Sled, Christopher K Macgowan
PURPOSE: We propose an analytical method for calculating blood hematocrit (Hct) and oxygen saturation (sO2 ) from measurements of its T1 and T2 relaxation times. THEORY: Through algebraic substitution, established two-compartment relationships describing R1=T1-1 and R2=T2-1 as a function of hematocrit and oxygen saturation were rearranged to solve for Hct and sO2 in terms of R1 and R2 . Resulting solutions for Hct and sO2 are the roots of cubic polynomials. METHODS: Feasibility of the method was established by comparison of Hct and sO2 estimates obtained from relaxometry measurements (at 1...
February 12, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28185808/a-sled-push-stimulus-potentiates-subsequent-20-m-sprint-performance
#3
Laurent B Seitz, Minas A Mina, G Gregory Haff
OBJECTIVES: The objective of this study was to examine the potentiating effects of performing a single sprint-style sled push on subsequent unresisted 20m sprint performance. DESIGN: Randomized crossover design. METHODS: Following a familiarization session, twenty rugby league players performed maximal unresisted 20m sprints before and 15s, 4, 8 and 12min after a single sled push stimulus loaded with either 75 or 125% body mass. The two sled push conditions were performed in a randomized order over a one-week period...
January 23, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28149342/two-man-bobsled-push-start-analysis
#4
Alexandre Dias Lopes, Sandra Regina Alouche
The importance of push start times on bobsled performance was evidenced by some studies, but at this moment there is no article to the authors' knowledge that describes the bobsled push start. Thus, the objectives of this study were to describe the two-man bobsled push start, analyze the differences between teams, and estimate the most important variable analyzed. We hypothesized that the pilot and brakeman athletes' movement patterns during a bobsled pushing start can be described. The images used in this study were obtained during the men's two-man XIV World Championship of Bobsled (2004)...
April 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28149027/sustained-low-efficiency-dialysis-in-septic-shock-hemodynamic-tolerability-and-efficacy
#5
Shakti Bedanta Mishra, Ratender Kumar Singh, Arvind Kumar Baronia, Banani Poddar, Afzal Azim, Mohan Gurjar
AIM OF THE STUDY: Acute kidney injury (AKI) in septic shock has poor outcomes. Sustained low-efficiency dialysis (SLED) is increasingly replacing continuous renal replacement therapy as the preferred modality in Intensive Care Units (ICUs). However, the essential aspects of hemodynamic tolerability and efficacy of SLED in septic shock AKI has been minimally studied. PATIENTS AND METHODS: We describe hemodynamic tolerability using modified vasopressor index (VI) and vasopressor dependency (VD) and efficacy using a combination of Kt/v, correction of acidosis, electrolyte, and fluid overload...
December 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28128881/the-effect-of-sustained-low-efficient-dialysis-versus-continuous-renal-replacement-therapy-on-renal-recovery-after-acute-kidney-injury-in-the-intensive-care-unit-a-systematic-review-and-meta-analysis
#6
REVIEW
Bernadett Kovacs, Katrina J Sullivan, Swapnil Hiremath, Rakesh V Patel
Acute kidney injury (AKI) is a significant contributing factor to the morbidity and mortality of critically ill adults, yet there remains controversy on the optimal renal replacement therapy mode for these patients. The aim of our systematic review was to determine the effect of sustained low-efficiency dialysis or continuous renal replacement therapy on patient outcomes in critically ill patients with AKI. A systematic search of Medline, Embase, CINAHL, and the Cochrane Library was conducted in February 2015...
January 27, 2017: Nephrology
https://www.readbyqxmd.com/read/28119205/sled-fixation-for-horizontal-medial-malleolus-fractures
#7
Adam M Wegner, Philip R Wolinsky, Robin Z Cheng, Michael A Robbins, Tanya C Garcia, Derek F Amanatullah
BACKGROUND: Horizontal fractures of the medial malleolus occur through exertion of various rotational forces on the ankle, including supination--external rotation, pronation--external rotation, and pronation-abduction. Many methods of fixation are employed for these fractures, but the optimal fixation construct remains unclear. METHODS: Horizontal medial malleolus osteotomies were performed in synthetic distal tibiae and randomized into two fixation groups: 1) two parallel unicortical cancellous screws or 2) medial malleolar sled fixation...
January 16, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28115646/response-of-novel-skeletal-muscle-biomarkers-in-dogs-to-drug-induced-skeletal-muscle-injury-or-sustained-endurance-exercise
#8
Katerina Vlasakova, Pamela Lane, Laura Michna, Nagaraja Muniappa, Frank D Sistare, Warren E Glaab
The skeletal muscle (SKM) injury biomarkers, skeletal troponin I (sTnI), myosin light chain 3 (Myl3), and creatine kinase muscle isoform (Ckm) have been shown recently to be more sensitive and specific for monitoring drug-induced SKM injury than the conventional biomarkers, aspartate transaminase (AST) and creatine kinase (CK) enzymatic assays in rat toxicology studies. To evaluate the utility of these SKM biomarkers across species, they were assessed in two dog models: a drug-induced injury study in Beagle dogs and a 160 km endurance exercise run completed by Alaskan sled dogs...
January 23, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28095025/the-influence-of-personal-protection-equipment-occupant-body-size-and-restraint-system-on-the-frontal-impact-responses-of-hybrid-iii-atds-in-tactical-vehicles
#9
Lauren Wood Zaseck, Nichole Ritchie Orton, Rebekah Gruber, Jonathan Rupp, Risa Scherer, Matthew Reed, Jingwen Hu
OBJECTIVE: Although advanced restraint systems, such as seatbelt pretensioners, and load limiters, can provide improved occupant protection in crashes, such technologies are currently not utilized in military vehicles. The design and use of military vehicles presents unique challenges to occupant safety - including differences in compartment geometry and occupant clothing and gear - that make direct application of optimal civilian restraint systems to military vehicles inappropriate. For military vehicle environments, finite element (FE) modeling can be used to assess various configurations of restraint systems and determine the optimal configuration that minimizes injury risk to the occupant...
January 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28051333/optimal-loading-for-maximising-power-during-sled-resisted-sprinting
#10
Matt R Cross, Matt Brughelli, Pierre Samozino, Scott R Brown, Jean-Benoit Morin
Purpose We sought to ascertain whether force-velocity-power relationships could be compiled from a battery of sled-resisted over-ground sprints, and to clarify and compare the optimal loading conditions for maximising power production for different athlete cohorts. Methods Recreational mixed-sport athletes (n=12) and sprinters (n=15) performed multiple trials of maximal sprints unloaded and towing a selection of sled masses (20-120% body-mass). Velocity data were collected by sports radar, and kinetics at peak velocity were quantified using friction coefficients and aerodynamic drag...
January 4, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28032302/the-1925-diphtheria-antitoxin-run-to-nome-alaska-a-public-health-illustration-of-human-animal-collaboration
#11
Basil H Aboul-Enein, William C Puddy, Jacquelyn E Bowser
Diphtheria is an acute toxin-mediated superficial infection of the respiratory tract or skin caused by the aerobic gram-positive bacillus Corynebacterium diphtheriae. The epidemiology of infection and clinical manifestations of the disease vary in different parts of the world. Historical accounts of diphtheria epidemics have been described in many parts of the world since antiquity. Developed in the late 19th century, the diphtheria antitoxin (DAT) played a pivotal role in the history of public health and vaccinology prior to the advent of the diphtheria-tetanus toxoids and acellular pertussis (DTaP) vaccine...
December 29, 2016: Journal of Medical Humanities
https://www.readbyqxmd.com/read/27967284/sled-towing-the-optimal-overload-for-peak-power-production
#12
Andrea Monte, Francesca Nardello, Paola Zamparo
PURPOSE: The effects of different loads on kinematic and kinetic variables during sled towing were investigated with the aim to identify the optimal overload for this specific sprint training. METHODS: Thirteen male sprinters (100m PB: 10.91±0.14 s) performed 5 maximal trials over a 20m distance in the following conditions: unloaded (UL) and with loads from +15% to +40% of the athlete's body mass (BM). In these calculations the sled mass and friction were taken into account...
December 14, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27905864/determining-friction-and-effective-loading-for-sled-sprinting
#13
Matt R Cross, Farhan Tinwala, Seth Lenetsky, Pierre Samozino, Matt Brughelli, Jean-Benoit Morin
Understanding the impact of friction in sled sprinting allows the quantification of kinetic outputs and the effective loading experienced by the athlete. This study assessed changes in the coefficient of friction (µk) of a sled sprint-training device with changing mass and speed to provide a means of quantifying effective loading for athletes. A common sled equipped with a load cell was towed across an athletics track using a motorised winch under variable sled mass (33.1-99.6 kg) with constant speeds (0...
December 1, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27871106/thoracic-injury-risk-curves-for-rib-deflections-of-the-sid-iis-build-level-d
#14
Annette L Irwin, Greg Crawford, David Gorman, Sikui Wang, Harold J Mertz
Injury risk curves for SID-IIs thorax and abdomen rib deflections proposed for future NCAP side impact evaluations were developed from tests conducted with the SID-IIs FRG. Since the floating rib guide is known to reduce the magnitude of the peak rib deflections, injury risk curves developed from SID-IIs FRG data are not appropriate for use with SID-IIs build level D. PMHS injury data from three series of sled tests and one series of whole-body drop tests are paired with thoracic rib deflections from equivalent tests with SID-IIs build level D...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27871105/development-and-full-body-validation-of-a-5th-percentile-female-finite-element-model
#15
Matthew L Davis, Bharath Koya, Jeremy M Schap, F Scott Gayzik
To mitigate the societal impact of vehicle crash, researchers are using a variety of tools, including finite element models (FEMs). As part of the Global Human Body Models Consortium (GHBMC) project, comprehensive medical image and anthropometrical data of the 5th percentile female (F05) were acquired for the explicit purpose of FEM development. The F05-O (occupant) FEM model consists of 981 parts, 2.6 million elements, 1.4 million nodes, and has a mass of 51.1 kg. The model was compared to experimental data in 10 validation cases ranging from localized rigid hub impacts to full body sled cases...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27871096/responses-and-injuries-to-pmhs-in-side-facing-and-oblique-seats-in-horizontal-longitudinal-sled-tests-per-faa-emergency-landing-conditions
#16
John R Humm, Narayan Yoganandan, Frank A Pintar, Richard L DeWeese, David M Moorcroft, Amanda M Taylor, Brian Peterson
The objective of the present exploratory study is to understand occupant responses in oblique and side-facing seats in the aviation environment, which are increasingly installed in modern aircrafts. Sled tests were conducted using intact Post Mortem Human Surrogates (PMHS) seated in custom seats approximating standard aircraft geometry. End conditions were selected to represent candidate aviation seat and restraint configurations. Three-dimensional head center-of-gravity linear accelerations, head angular velocities, and linear accelerations of the T1, T6, and T12 spinous processes, and sacrum were obtained...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27834560/very-heavy-sled-training-for-improving-horizontal-force-output-in-soccer-players
#17
Jean-Benoît Morin, George Petrakos, Pedro Jimenez-Reyes, Scott R Brown, Pierre Samozino, Matt R Cross
Sprint running acceleration is a key feature of physical performance in team sports, and recent literature shows that the ability to generate large magnitudes of horizontal ground reaction force and mechanical effectiveness of force application are paramount. We tested the hypothesis that very-heavy loaded sled sprint training would induce an improvement in horizontal force production, via an increased effectiveness of application. Training-induced changes in sprint performance and mechanical outputs were computed using a field method based on velocity-time data, before and after an 8-week protocol (16 sessions of 10x20-m sprints)...
November 11, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27824504/repeatability-study-of-replicate-crash-tests-a-signal-analysis-approach
#18
Jeremy Seppi, Jacek Toczyski, Jeff R Crandall, Jason Kerrigan
OBJECTIVE: To provide an objective basis on which to evaluate the repeatability of vehicle crash test methods, a recently developed signal analysis method was used to evaluate correlation of sensor time history data between replicate vehicle crash tests. The goal of this study was to evaluate the repeatability of rollover crash tests performed with the Dynamic Rollover Test System (DRoTS) relative to other vehicle crash test methods. METHODS: Test data from DRoTS tests, Deceleration Rollover Sled (DRS) tests, frontal crash tests, frontal offset crash tests, small overlap crash tests, Small Overlap Impact (SOI) crash tests, and oblique crash tests were obtained from the literature and publicly available databases (the National Highway Traffic Safety Administration vehicle database and the Insurance Institute for Highway Safety TechData) to examine crash test repeatability...
November 8, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27813331/sliding-on-dna-from-peptides-to-small-molecules
#19
Kan Xiong, Graham S Erwin, Aseem Z Ansari, Paul C Blainey
Many DNA binding proteins utilize one-dimensional (1D) diffusion along DNA to accelerate their DNA target recognition. Although 1D diffusion of proteins along DNA has been studied for decades, a quantitative understanding is only beginning to emerge and few chemical tools are available to apply 1D diffusion as a design principle. Recently, we discovered that peptides can bind and slide along DNA-even transporting cargo along DNA. Such molecules are known as molecular sleds. Here, to advance our understanding of structure-function relationships governing sequence nonspecific DNA interaction of natural molecular sleds and to explore the potential for controlling sliding activity, we test the DNA binding and sliding activities of chemically modified peptides and analogs, and show that synthetic small molecules can slide on DNA...
November 21, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27689132/insulin-like-growth-factor-1-and-selected-insulin-like-growth-factor-binding-protein-concentrations-during-an-ultramarathon-sled-dog-race
#20
Matthew W Brunke, Christopher W Frye, Corri B Levine, Cristina Hansen, Joseph J Wakshlag
The objective of this study was to investigate the effects of running a 1000-mile (1600 km) endurance sled dog race on serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding proteins 1 and 3 (IGFBP-1 and IGFBP-3). Serum was examined from 12 sled dogs prior to the race, at midrace (approximately 690 km), and again at the finish. IGF-1, IGFBP-1, and IGFBP-3 were assessed using radioimmunoassay or enzyme linked immune-absorbance assays. Mean prerace concentrations were significantly higher than midrace and end-race concentrations at 215...
2016: TheScientificWorldJournal
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