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https://www.readbyqxmd.com/read/29352529/measuring-and-improving-the-quality-of-mental-health-care-a-global-perspective
#1
Amy M Kilbourne, Kathryn Beck, Brigitta Spaeth-Rublee, Parashar Ramanuj, Robert W O'Brien, Naomi Tomoyasu, Harold Alan Pincus
Mental disorders are common worldwide, yet the quality of care for these disorders has not increased to the same extent as that for physical conditions. In this paper, we present a framework for promoting quality measurement as a tool for improving quality of mental health care. We identify key barriers to this effort, including lack of standardized information technology-based data sources, limited scientific evidence for mental health quality measures, lack of provider training and support, and cultural barriers to integrating mental health care within general health environments...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29352362/a-preliminary-examination-of-the-link-between-maternal-experiential-avoidance-and-parental-accommodation-in-anxious-and-non-anxious-children
#2
Leah Feinberg, Caroline Kerns, Donna B Pincus, Jonathan S Comer
Studies point to parental experiential avoidance (EA) as a potential correlate of maladaptive parenting behaviors associated with child anxiety. However, research has not examined the relationship between EA and parental accommodation of child anxiety, nor the extent to which parental negative beliefs about child anxiety help explain such a relationship. In a sample of mothers (N = 45) of anxious and non-anxious children, the present study investigated the potential link between maternal EA and accommodation of child anxiety and whether this link may be indirectly accounted for via maternal negative beliefs about child anxiety...
January 19, 2018: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29302928/trends-in-md-phd-graduates-entering-psychiatry-assessing-the-physician-scientist-pipeline
#3
Melissa R Arbuckle, Sean X Luo, Harold Alan Pincus, Joshua A Gordon, Joyce Y Chung, Mark Chavez, Maria A Oquendo
OBJECTIVE: The goal of this study was to identify trends in MD/PhD graduates entering psychiatry, to compare these trends with other specialties, and to review strategies for enhancing the physician-scientist pipeline. METHODS: Data on 226,588 medical students graduating from Liaison Committee on Medical Education accredited programs between 1999 and 2012 (6626 MD/PhDs) were used to evaluate the number, percentage, and proportion of MD/PhDs entering psychiatry in comparison with other specialties (neurology, neurosurgery, internal medicine, family medicine, and radiation oncology)...
January 4, 2018: Academic Psychiatry
https://www.readbyqxmd.com/read/29236543/rorschach-assessment-of-two-distinctive-personality-states-of-a-person-with-dissociative-identity-disorder
#4
Ellen Hartmann, Kirsten Benum
This case study used test data from a patient with Dissociative Identity Disorder (DID; American Psychiatric Association, 2013 ) to illustrate how two main personality states of the patient ("Ann" and "Ben") seemed to function. The Rorschach Performance Assessment System (R-PAS; Meyer, Viglione, Mihura, Erard, & Erdberg, 2011 ) and the Inventory of Interpersonal Problems-Circumplex (IIP-64; Horowitz, Alden, Wiggins, & Pincus, 2000 ), administered to Ann and Ben in separate settings, exposed two diverse R-PAS and IIP-64 profiles...
December 13, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29226598/the-time-has-come-for-dimensional-personality-disorder-diagnosis
#5
Christopher J Hopwood, Roman Kotov, Robert F Krueger, David Watson, Thomas A Widiger, Robert R Althoff, Emily B Ansell, Bo Bach, R Michael Bagby, Mark A Blais, Marina A Bornovalova, Michael Chmielewski, David C Cicero, Christopher Conway, Barbara De Clerq, Filip De Fruyt, Anna R Docherty, Nicholas R Eaton, John F Edens, Miriam K Forbes, Kelsie T Forbush, Michael P Hengartner, Masha Y Ivanova, Daniel Leising, W John Livesley, Mark R Lukowitsky, Donald R Lynam, Kristian E Markon, Joshua D Miller, Leslie C Morey, Stephanie N Mullins-Sweatt, J Hans Ormel, Christopher J Patrick, Aaron L Pincus, Camilo Ruggero, Douglas B Samuel, Martin Sellbom, Tim Slade, Jennifer L Tackett, Katherine M Thomas, Timothy J Trull, David D Vachon, Irwin D Waldman, Monika A Waszczuk, Mark H Waugh, Aidan G C Wright, Mathew M Yalch, David H Zald, Johannes Zimmermann
No abstract text is available yet for this article.
December 11, 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/29225915/mdhaq-rapid3-scores-in-patients-with-osteoarthritis-are-similar-to-or-higher-than-in-patients-with-rheumatoid-arthritis-a-cross-sectional-study-from-current-routine-rheumatology-care-at-four-sites
#6
Carlos El-Haddad, Isabel Castrejon, Kathryn A Gibson, Yusuf Yazici, Martin J Bergman, Theodore Pincus
Objective: To compare patients with a primary diagnosis of osteoarthritis (OA) versus rheumatoid arthritis (RA) for scores on a patient self-report MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data 3), and for physician global assessment (DOCGL). Methods: All patients with all diagnoses complete an MDHAQ/RAPID3 at all routine rheumatology visits in the waiting area before seeing a rheumatologist at four sites, one in Australia and three in the USA...
2017: RMD Open
https://www.readbyqxmd.com/read/29222620/the-link-between-anxiety-severity-and-irritability-among-anxious-youth-evaluating-the-mediating-role-of-sleep-problems
#7
Bridget Poznanski, Danielle Cornacchio, Stefany Coxe, Donna B Pincus, Dana L McMakin, Jonathan S Comer
Although recent studies have linked pediatric anxiety to irritability, research has yet to examine the mechanisms through which youth anxiety may be associated with irritability. Importantly, sleep related problems (SRPs) have been associated with both child anxiety and irritability, but research has not considered whether the link between youth anxiety and irritability may be accounted for by SRPs. The present study investigated whether SRPs mediated the relationship between anxiety severity and irritability in a large sample of treatment-seeking anxious youth (N = 435; ages 7-19 years, M = 12...
December 8, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29219242/behavioural-assessment-unit-improves-outcomes-for-patients-with-complex-psychosocial-needs
#8
George Braitberg, Marie Gerdtz, Susan Harding, Steven Pincus, Michelle Thompson, Jonathan Knott
OBJECTIVE: We aimed to assess the impact of a new model of care for patients presenting to the ED with acute behavioural disturbance. METHODS: This pre-/post-intervention study involved creating a dedicated, highly resourced six bed unit, the behavioural assessment unit (BAU). Co-located with the ED at the Royal Melbourne Hospital, the unit was designed to fast-track the admission of patients affected by intoxication, mental illness or psychosocial crisis and provide front-loaded interventions...
December 8, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29218808/the-feasibility-and-acceptability-of-a-physical-activity-intervention-for-older-people-with-chronic-musculoskeletal-pain-the-ipopp-pilot-trial-protocol
#9
E L Healey, C Jinks, N E Foster, C A Chew-Graham, T Pincus, L Hartshorne, K Cooke, E Nicholls, J Proctor, M Lewis, S Dent, S Wathall, E M Hay, J McBeth
INTRODUCTION: This pilot trial will inform the design and methods of a future full-scale randomized controlled trial (RCT) and examine the feasibility, acceptability and fidelity of the Increasing Physical activity in Older People with chronic Pain (iPOPP) intervention, a healthcare assistant (HCA)-supported intervention to promote walking in older adults with chronic musculoskeletal pain in a primary care setting. METHODS AND ANALYSIS: The iPOPP study is an individually randomized, multicentre, three-parallel-arm pilot RCT...
December 8, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/29211967/efficacy-and-safety-of-amphetamine-extended-release-oral-suspension-in-children-with-attention-deficit-hyperactivity-disorder
#10
Ann C Childress, Sharon B Wigal, Matthew N Brams, John M Turnbow, Yulia Pincus, Heidi W Belden, Sally A Berry
OBJECTIVES: To determine the efficacy and safety of amphetamine extended-release oral suspension (AMPH EROS) in the treatment of attention-deficit/hyperactivity disorder (ADHD) in a dose-optimized, randomized, double-blind, parallel-group study. METHODS: Boys and girls aged 6 to 12 years diagnosed with ADHD were enrolled. During a 5-week, open-label, dose-optimization phase, patients began treatment with 2.5 or 5 mg/day of AMPH EROS; doses were titrated until an optimal dose (maximum 20 mg/day) was reached...
December 6, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29204597/association-of-overlapping-surgery-with-increased-risk-for-complications-following-hip-surgery-a-population-based-matched-cohort-study
#11
Bheeshma Ravi, Daniel Pincus, David Wasserstein, Anand Govindarajan, Anjie Huang, Peter C Austin, Richard Jenkinson, Patrick D G Henry, J Michael Paterson, Hans J Kreder
Importance: Overlapping surgery, also known as double-booking, refers to a controversial practice in which a single attending surgeon supervises 2 or more operations, in different operating rooms, at the same time. Objective: To determine if overlapping surgery is associated with greater risk for complications following surgical treatment for hip fracture and arthritis. Design, Setting, and Participants: This was a retrospective population-based cohort study in Ontario, Canada (population, 13...
January 1, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29195076/migrating-platelets-are-mechano-scavengers-that-collect-and-bundle-bacteria
#12
Florian Gaertner, Zerkah Ahmad, Gerhild Rosenberger, Shuxia Fan, Leo Nicolai, Benjamin Busch, Gökce Yavuz, Manja Luckner, Hellen Ishikawa-Ankerhold, Roman Hennel, Alexandre Benechet, Michael Lorenz, Sue Chandraratne, Irene Schubert, Sebastian Helmer, Bianca Striednig, Konstantin Stark, Marek Janko, Ralph T Böttcher, Admar Verschoor, Catherine Leon, Christian Gachet, Thomas Gudermann, Michael Mederos Y Schnitzler, Zachary Pincus, Matteo Iannacone, Rainer Haas, Gerhard Wanner, Kirsten Lauber, Michael Sixt, Steffen Massberg
Blood platelets are critical for hemostasis and thrombosis and play diverse roles during immune responses. Despite these versatile tasks in mammalian biology, their skills on a cellular level are deemed limited, mainly consisting in rolling, adhesion, and aggregate formation. Here, we identify an unappreciated asset of platelets and show that adherent platelets use adhesion receptors to mechanically probe the adhesive substrate in their local microenvironment. When actomyosin-dependent traction forces overcome substrate resistance, platelets migrate and pile up the adhesive substrate together with any bound particulate material...
November 30, 2017: Cell
https://www.readbyqxmd.com/read/29189603/the-dynamics-of-stress-and-fatigue-across-menopause-attractors-coupling-and-resilience
#13
Lisa Taylor-Swanson, Alexander E Wong, David Pincus, Jonathan E Butner, Jennifer Hahn-Holbrook, Mary Koithan, Kathryn Wann, Nancy F Woods
OBJECTIVE: The objective of this study was to evaluate the regulatory dynamics between stress and fatigue experienced by women during the menopausal transition (MT) and early postmenopause (EPM). Fatigue and perceived stress are commonly experienced by women during the MT and EPM. We sought to discover relationships between these symptoms and to employ these symptoms as possible markers for resilience. METHODS: Participants were drawn from the longitudinal Seattle Midlife Women's Health Study...
November 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29183076/association-between-wait-time-and-30-day-mortality-in-adults-undergoing-hip-fracture-surgery
#14
Daniel Pincus, Bheeshma Ravi, David Wasserstein, Anjie Huang, J Michael Paterson, Avery B Nathens, Hans J Kreder, Richard J Jenkinson, Walter P Wodchis
Importance: Although wait times for hip fracture surgery have been linked to mortality and are being used as quality-of-care indicators worldwide, controversy exists about the duration of the wait that leads to complications. Objective: To use population-based wait-time data to identify the optimal time window in which to conduct hip fracture surgery before the risk of complications increases. Design, Setting, and Participants: Population-based, retrospective cohort study of adults undergoing hip fracture surgery between April 1, 2009, and March 31, 2014, at 72 hospitals in Ontario, Canada...
November 28, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29158454/direct-medical-costs-of-motorcycle-crashes-in-ontario
#15
Daniel Pincus, David Wasserstein, Avery B Nathens, Yu Qing Bai, Donald A Redelmeier, Walter P Wodchis
BACKGROUND: There is no reliable estimate of costs incurred by motorcycle crashes. Our objective was to calculate the direct costs of all publicly funded medical care provided to individuals after motorcycle crashes compared with automobile crashes. METHODS: We conducted a population-based, matched cohort study of adults in Ontario who presented to hospital because of a motorcycle or automobile crash from 2007 through 2013. For each case, we identified 1 control absent a motor vehicle crash during the study period...
November 20, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29143460/transient-neonatal-zinc-deficiency-in-exclusively-breastfed-preterm-infants
#16
Lauren Watson, David Cartwright, Luke A Jardine, David Pincus, Pieter Koorts, Sebastien Kury, Stephanie Bezieau, Shane George, Susan Moloney, Johanna Holt, David Coman
No abstract text is available yet for this article.
November 16, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29114017/a-microrna-feedback-loop-regulates-global-microrna-abundance-during-aging
#17
Sachi Inukai, Zachary Pincus, Alexandre de Lencastre, Frank J Slack
Expression levels of many microRNAs (miRNAs) change during aging, notably declining globally in a number of organisms and tissues across taxa. However, little is known about the mechanisms or the biological relevance for this change. We investigated the network of genes that controls miRNA transcription and processing during C. elegans aging. We found that miRNA biogenesis genes are highly networked with transcription factors and aging-associated miRNAs. In particular, miR-71, known to influence lifespan and itself upregulated during aging, represses alg-1/Argonaute expression post-transcriptionally during aging...
November 7, 2017: RNA
https://www.readbyqxmd.com/read/29112801/value-of-rapid3-in-patients-with-psa-results-from-the-ticopa-and-lopas-ii-databases
#18
Laura C Coates, William Tillett, Gavin Shaddick, Theodore Pincus, Arthur Kavanaugh, Philip S Helliwell
OBJECTIVE: To analyze RAPID3, a patient-reported, composite index, designed initially for feasibility in clinical care. RAPID3 was developed in rheumatoid arthritis, but has been found useful in many rheumatic diseases. We analysed RAPID3 in patients with psoriatic arthritis (PsA). METHODS: Post-hoc analyses were performed on two independent datasets, the tight control of PsA (TICOPA) clinical trial, and the long-term outcome in PsA study (LOPAS II), an observational cohort...
November 7, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29104895/serial-immunoprecipitation-of-3xflag-v5-tagged-yeast-proteins-to-identify-specific-interactions-with-chaperone-proteins
#19
Xu Zheng, David Pincus
This method was generated to isolate high affinity protein complexes from yeast lysate by performing serial affinity purification of doubly tagged 3×FLAG/V5 proteins. First, the bait protein of interest is immunoprecipitated by anti-FLAG-conjugated magnetic beads and gently eluted by 3×FLAG antigen peptide. Next, the bait protein is recaptured from the first eluate by anti-V5-conjugated magnetic beads and eluted with ionic detergent. In this manner, the majority of abundant, nonspecific proteins remain either bound to the first beads or in the first eluate, allowing pure, high affinity complexes to be obtained...
June 20, 2017: Bio-protocol
https://www.readbyqxmd.com/read/29077660/successful-resuscitation-of-maternal-cardiac-arrest-with-disseminated-intravascular-coagulation-guided-by-rotational-thromboelastometry-and-transesophageal-echocardiography-a-case-report
#20
Hannah Brown, Helen L Barrett, Julie Lee, Jason M Pincus, Rebecca M Kimble, Victoria A Eley
We present a case of maternal cardiac arrest during an elective cesarean delivery. Transesophageal echocardiography identified a large pulmonary artery mass, and guided resuscitation efforts. After return of spontaneous circulation, the patient developed disseminated intravascular coagulation with massive hemorrhage. Blood product selection and volume replacement were guided by rotational thromboelastometry and transesophageal echocardiography, respectively. Correction of coagulopathy was observed clinically and confirmed by rotational thromboelastometry...
October 26, 2017: A & A Case Reports
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