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https://www.readbyqxmd.com/read/28729328/comparative-safety-of-antiepileptic-drugs-for-neurological-development-in-children-exposed-during-pregnancy-and-breast-feeding-a-systematic-review-and-network-meta-analysis
#1
Areti Angeliki Veroniki, Patricia Rios, Elise Cogo, Sharon E Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R Hemmelgarn, Fatemeh Yazdi, Jennifer D'Souza, Heather MacDonald, Andrea C Tricco
OBJECTIVES: Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children exposed in utero or during breast feeding. DESIGN AND SETTING: Systematic review and Bayesian random-effects network meta-analysis (NMA). MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched until 27 April 2017. Screening, data abstraction and quality appraisal were completed in duplicate by independent reviewers. PARTICIPANTS: 29 cohort studies including 5100 infants/children...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28728347/pros-and-cons-of-health-transformation-program-in-iran-evidence-from-financial-outcomes-at-household-level
#2
Enayatollah Homaie Rad, Vahid Yazdi-Feyzabadi, Shahrokh Yousefzadeh-Chabok, Abolhasan Afkar, Ahmad Naghibzadeh Tahami
Purpose: Health transformation program (HTP) is one of the recent reforms in health system of Iran implemented in early 2014. Improving the equity of payments and reducing out of pocket (OOP) and catastrophic health expenditures (CHE) were some of the program's important goals. In this study these goals were evaluated using a before-after analysis. Methods: Household income and expenditures data of Guilan province were gathered for years 2013-2015. OOP payments for outpatient, inpatient and drug services were calculated and the results were compared using propensity score matching technique after adjustment of confounding variables...
July 18, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28700044/prevalence-of-and-risk-factors-for-multidrug-resistant-tuberculosis-in-iran-and-its-neighboring-countries-systematic-review-and-meta-analysis
#3
Worku Jimma, Marjan Ghazisaeedi, Leila Shahmoradi, Ahmed Abdulahi Abdurahman, Sharareh Rostam Niakan Kalhori, Mahshid Nasehi, Sharifi Yazdi, Reza Safdari
Tuberculosis, in particular drug-resistant tuberculosis, is of global concern due to the high mortality and morbidity associated with it annually. The aim of this study was to determine the prevalence of and the risk factors for multidrug-resistant tuberculosis in Iran and its neighboring countries. Four databases (PubMed, BioMed Central, EMBASE, and Web of Science) were searched using key terms. Nineteen eligible articles were identified, of which 12 and seven were used for quantitative and qualitative analysis, respectively...
May 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28694453/portable-and-error-free-dna-based-data-storage
#4
S M Hossein Tabatabaei Yazdi, Ryan Gabrys, Olgica Milenkovic
DNA-based data storage is an emerging nonvolatile memory technology of potentially unprecedented density, durability, and replication efficiency. The basic system implementation steps include synthesizing DNA strings that contain user information and subsequently retrieving them via high-throughput sequencing technologies. Existing architectures enable reading and writing but do not offer random-access and error-free data recovery from low-cost, portable devices, which is crucial for making the storage technology competitive with classical recorders...
July 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28675656/direct-creation-of-highly-conductive-laser-induced-graphene-nanocomposites-from-polymer-blends
#5
Alireza Zehtab Yazdi, Ivonne Otero Navas, Ahmed Abouelmagd, Uttandaraman Sundararaj
The current state-of-the-art mixing strategies of nanoparticles with insulating polymeric components have only partially utilized the unique electrical conductivity of graphene in nanocomposite systems. Herein, this paper reports a nonmixing method of direct creation of polymer/graphene nanocomposites from polymer blends via laser irradiation. Polycarbonate-laser-induced graphene (PC-LIG) nanocomposite is produced from a PC/polyetherimide (PC/PEI) blend after exposure to commercially available laser scribing with a power of ≈6 W and a speed of ≈2 cm s(-1) ...
July 4, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28667027/synergy-between-paclitaxel-and-anti-cancer-peptide-pnc-27-in-the-treatment-of-ovarian-cancer
#6
Ioannis Alagkiozidis, Constantine Gorelick, Tana Shah, Yi-Ju Amy Chen, Vinita Gupta, Dimitre Stefanov, Abhi Amarnani, Yi-Chun Lee, Ovadia Abulafia, Ehsan Sarafraz-Yazdi, Josef Michl
OBJECTIVES: Paclitaxel is widely used in the treatment of gynecologic malignancies. It targets tumor cells in the M phase of the cell cycle. Cells in other phases survive the insult and repopulate the tumor. PNC-27 is a peptide synthesized of amino acids of the p53-MDM-2 binding domain. It kills various cancer cell lines in a dose-dependent manner. The goal of this study is to assess ovarian cancer cells' sensitivity to PNC-27 after surviving exposure to paclitaxel and to investigate the potential for synergy between PNC-27 and paclitaxel in the treatment of ovarian cancer...
May 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/28665739/the-placental-vascular-endothelial-growth-factor-polymorphisms-and-preeclampsia-preeclampsia-severity
#7
Farshid Keshavarzi, Abbas Mohammadpour-Gharehbagh, Mahnaz Shahrakipour, Batool Teimoori, Atefeh Yazdi, Minoo Yaghmaei, Mehrnaz Naroeei-Nejad, Saeedeh Salimi
Preeclampsia (PE) is a serious pregnancy-specific condition, which originates from placenta and finishes after delivery. The present study has investigated the association between placental VEGF I/D (rs35569394), -1154G/A (rs1570360), and -634G/C(rs2010963) polymorphisms and maternal VEGF -2549 I/D (rs35569394) polymorphism with PE and PE severity. In this case-control study, the maternal blood of 217 women with PE and 210 normotensive pregnant women and the placenta of 84 PE women and 103 normotensive women were collected after delivery...
June 30, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28656759/single-atomic-ruthenium-catalytic-sites-on-nitrogen-doped-graphene-for-oxygen-reduction-reaction-in-acidic-medium
#8
Chenhao Zhang, Junwei Sha, Huilong Fei, Mingjie Liu, Sadegh Yazdi, Jibo Zhang, Qifeng Zhong, Xiaolong Zou, Naiqin Zhao, Haisheng Yu, Zheng Jiang, Emilie Ringe, Boris I Yakobson, Juncai Dong, Dongliang Chen, James M Tour
The cathodic oxygen reduction reaction (ORR) is essential in the electrochemical energy conversion of fuel cells. Here, through the NH3 atmosphere annealing of a graphene oxide (GO) precursor containing trace amounts of Ru, we have synthesized atomically dispersed Ru on nitrogen-doped graphene that performs as an electrocatalyst for the ORR in acidic medium. The Ru/nitrogen-doped GO catalyst exhibits excellent four-electron ORR activity, offering onset and half-wave potentials of 0.89 and 0.75 V, respectively, vs a reversible hydrogen electrode (RHE) in 0...
June 28, 2017: ACS Nano
https://www.readbyqxmd.com/read/28656163/responsiveness-of-static-and-dynamic-postural-balance-measures-in-patients-with-anterior-cruciate-ligament-reconstruction-following-physiotherapy-intervention
#9
Neda Mostafaee, Mohammad J Shaterzadeh Yazdi, Hossein Negahban, Shahin Goharpey, Mohammad Mehravar, Nahid Pirayeh
BACKGROUND: The main goal of physiotherapy for patients with anterior cruciate ligament reconstruction (ACL-R) is to improve postural control and retain knee function. Therefore, clinicians need to use evaluative tools that assess postural changes during physiotherapy. To maximize the clinical utility of the results of these tools, the extracted measures should have appropriate psychometric properties of reliability, validity and responsiveness. No study has yet addressed responsiveness of postural measures in these patients...
May 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28655472/induction-of-skin-pathogenic-th22-cells-by-epicutaneous-allergen-exposure
#10
Ivana Glocova, Jürgen Brück, Julia Geisel, Eva Müller-Hermelink, Katja Widmaier, Amir S Yazdi, Martin Röcken, Kamran Ghoreschi
BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease with dysfunction of the skin barrier, an abnormal immune response and frequent allergies to environmental antigens like food antigens. Clinical observations suggest that certain diets can influence the course of AD. OBJECTIVE: Here we compared the phenotype of food allergen-specific T cells activated through skin or gut allergen exposure to transfer skin inflammation into naïve recipients upon epicutaenous allergen challenge...
June 9, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28646705/identification-and-in-vitro-characterization-of-novel-nanobodies-against-human-granulocyte-colony-stimulating-factor-receptor-to-provide-inhibition-of-g-csf-function
#11
Hamid Bakherad, Seyed Latif Mousavi Gargari, Zargham Sepehrizadeh, Hossein Aghamollaei, Ramezan Ali Taheri, Maryam Torshabi, Mojtaba Tabatabaei Yazdi, Walead Ebrahimizadeh, Neda Setayesh
It has been shown that Granulocyte colony-stimulating factor (G-CSF) has a higher expression in malignant tumors, and anti-G-CSF therapy considerably decreases tumor growth, tumor vascularization and metastasis. Thus, blocking the signaling pathway of G-CSF could be beneficial in cancer therapy. This study is aimed at designing and producing a monoclonal nanobody that could act as an antagonist of G-CSF receptor. Nanobodies are the antigen binding fragments of camelid single-chain antibodies, also known as VHH...
June 21, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28634193/design-improvements-for-personal-protective-equipment-used-in-ebola-and-other-epidemic-outbreaks
#12
Margaret Glancey, Patience Osei, William Alexander Patterson, Matthew Petney, Laura Scavo, Chandrakant Ruparelia, Soumyadipta Acharya, Youseph Yazdi
No abstract text is available yet for this article.
June 27, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28633807/differential-induction-of-atf3-and-ho-1-in-myeloid-cells-and-keratinocytes-via-dimethylfumarate-or-cyclosporine-a
#13
Stefanie Müller, Nikola Smatlik, Marc Burian, Kamran Ghoreschi, Martin Röcken, Amir S Yazdi
BACKGROUND: Chronic inflammatory skin diseases are characterized by controlled proliferation of keratinocytes. Here, activating transcription factor 3 (ATF3) might play a fundamental role. In these inflammatory diseases, proliferation is controlled and only rarely leads to cancer development which can be supported by an inflammatory microenvironment. ATF3 is a dual function protein as it suppresses pro-inflammatory IL-6 and IL-8, but also acts as a pro-oncogenic factor by the suppression of p53...
June 12, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28616826/deposition-of-crystalline-hydroxyapatite-nano-particle-on-zirconia-ceramic-a-potential-solution-for-the-poor-bonding-characteristic-of-zirconia-ceramics-to-resin-cement
#14
Abbas Azari, Sakineh Nikzad, Arash Yazdani, Faezeh Atri, Abbas Fazel Anvari-Yazdi
The poor bonding strength of zirconia to different dental substrates is one of the challenging issues in restorative dentistry. Hydroxyapatite is an excellent biocompatible material with fine bonding properties. In this study, it was hypothesized that hydroxyapatite coating on zirconia would improve its bond strength. Forty-five zirconia blocks were prepared and randomly divided into three groups: hydroxyapatite coating, sandblasting, and no preparation (control). The blocks were bonded to cement and the micro-shear bond strength was measured following load application...
July 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28584530/an-overview-on-autologous-fibrin-glue-in-bone-tissue-engineering-of-maxillofacial-surgery
#15
REVIEW
Azizollah Khodakaram-Tafti, Davood Mehrabani, Hanieh Shaterzadeh-Yazdi
The purpose of this review is to have an overview on the applications on the autologous fibrin glue as a bone graft substitute in maxillofacial injuries and defects. A search was conducted using the databases such as Medline or PubMed and Google Scholar for articles from 1985 to 2016. The criteria were "Autograft," "Fibrin tissue adhesive," "Tissue engineering," "Maxillofacial injury," and "Regenerative medicine." Bone tissue engineering is a new promising approach for bone defect reconstruction. In this technique, cells are combined with three-dimensional scaffolds to provide a tissue-like structure to replace lost parts of the tissue...
March 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28583860/effectiveness-of-different-compression-to-ventilation-methods-for-cardiopulmonary-resuscitation-a-systematic-review
#16
REVIEW
Huda M Ashoor, Erin Lillie, Wasifa Zarin, Ba' Pham, Paul A Khan, Vera Nincic, Fatemeh Yazdi, Marco Ghassemi, John Ivory, Roberta Cardoso, Gavin D Perkins, Allan R de Caen, Andrea C Tricco
AIM: To compare the effectiveness of different compression-to-ventilation methods during cardiopulmonary resuscitation (CPR) in patients with cardiac arrest. METHODS: We searched MEDLINE and Cochrane Central Register of Controlled Trials from inception until January 2016. We included experimental, quasi-experimental, and observational studies that compared different chest compression-to-ventilation ratios during CPR for all patients and assessed at least one of the following outcomes: favourable neurological outcomes, survival, return of spontaneous circulation (ROSC), and quality of life...
June 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28572924/physicochemical-functional-and-nutritional-characteristics-of-stabilized-rice-bran-form-tarom-cultivar
#17
Ali Rafe, Alireza Sadeghian, Seyedeh Zohreh Hoseini-Yazdi
Extrusion is a multistep thermal process which has been utilized in a wide spectrum of food preparations. The effect of extrusion processing on the physicochemical, nutritional, and functional properties of Tarom cultivar rice bran was studied. However, the color of rice bran was improved by extrusion processing, but the protein content was reduced in the stabilized rice bran, which can be related to the denaturation of protein. Extrusion had also a reduction significant effect on the phytic acid as well as vitamin E in rice bran...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28561991/development-of-a-novel-bioactive-glass-suitable-for-osteosarcoma-related-bone-grafts
#18
Alireza Rahimnejad Yazdi, Lawrence Torkan, Stephen D Waldman, Mark R Towler
In this study, zinc borate-based glasses with increasing gallium content (0, 2.5, 5, 10, and 15 wt % Ga) were synthesized and their effect on the viability and proliferation of preosteoblasts and osteosarcoma cancer cells were investigated. Methyl thiazolyl tetrazolium (MTT) cell viability assays using glass degradation extracts revealed that the extracts from glasses with lower Ga contents could enhance the viability of preosteoblasts, while extracts from the glass composition with 15 wt % Ga caused statistically significant reduction of their viability...
May 31, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28549873/comparison-of-the-recovery-rate-of-otomycosis-using-betadine-and-clotrimazole-topical-treatment
#19
Mohammad Reza Mofatteh, Zahra Naseripour Yazdi, Masoud Yousefi, Mohammad Hasan Namaei
INTRODUCTION: Otomycosis is a common diseases that can be associated with many complications including involvement of the inner ear and mortality in rare cases. Management of otomycosis can be challenging, and requires a close follow-up. Treatment options for otomycosis include local debridement, local and systemic antifungal agents and utilization of topical antiseptics. OBJECTIVE: This study was designed to compare the recovery rate of otomycosis using two therapeutic methods; topical betadine (Povidone-iodine) and clotrimazole...
May 6, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28530539/preparation-optimization-and-physicochemical-characterization-of-aripiprazole-loaded-nano-porous-in-situ-forming-implant
#20
Ashkan Hedayati, Sina Ghafurzadeh Yazdi, Pouya Dehghankelishadi, Nika Bahari Javan, Hamid Akbari, Farid A Dorkoosh
BACKGROUND: Multiple applications of antipsychotic agents are the main obstacle upon treatment of schizophrenia. Due to behavioral abnormalities, low compliance is observed in the most of psychotic patients. Designing of new drug delivery systems to overcome compliance problem seems to be necessary. In situ forming implants are a suitable choice for delivery of antipsychotic agents due to easy administration process and sustained release kinetics. OBJECTIVE: In this study, a novel poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) based nano-porous in situ implant system is developed for delivery of aripiprazole...
May 22, 2017: Pharmaceutical Nanotechnology
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