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Mahnaz Abbasi, Mohammadali Zohal, Banafsheh Atapour, Zohreh Yazdi
Introduction. Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Proper diagnosis of osteoporosis as a systemic adverse effect of COPD is of significant importance. The present study aimed at evaluating the prevalence of osteoporosis and its risk factors in men suffering from COPD in Qazvin (2014). Methods. This descriptive-analytical study was conducted on 90 patients with COPD using random sampling. Anthropometric data and results from physical examination were collected...
2016: International Journal of Chronic Diseases
Behrooz Alizadeh Behbahani, Fakhri Shahidi, Farideh Tabatabaei Yazdi, Seyed Ali Mortazavi, Mohebbat Mohebbi
In this study, Plantago major seed mucilage (PMSM) was extracted from whole seeds using hot-water extraction (HWE). The dill (D) essential oil components were identified through gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) and its antioxidant properties were examined through the methods of 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant potential (FRAP) and ß-carotene-linoleic acid assay (B-CL). Total phenolic content (TPC) was characterized through the Folin-Ciocalteu method and the antimicrobial effect was evaluated on 10 pathogenic microorganisms...
October 19, 2016: International Journal of Biological Macromolecules
Katharina Meier, Stefan K Drexler, Franziska C Eberle, Karine Lefort, Amir S Yazdi
Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an important adaptor protein for inflammasome activation, mediating the secretion of protumorigenic innate cytokines. However, ASC is also known to trigger apoptosis in tumor cells, acting as a tumor-suppressor gene, which is lost in several human cancers. The aim of this study was to evaluate the clinical significance of ASC in human cutaneous squamous cell carcinoma (SCC). Initially, ASC expression was immunohistochemically evaluated in non-metastic and metastatic SCC...
2016: PloS One
Anoosheh Yazdi, Matthias Sperl
We consider a two-dimensional model system of Brownian particles in which slow particles are accelerated while fast particles are damped. The motion of the individual particles is described by a Langevin equation with Rayleigh-Helmholtz velocity-dependent friction. In the case of noninteracting particles, the time evolution equations lead to a non-Gaussian velocity distribution. The velocity-dependent friction allows negative values of the friction or energy intakes by slow particles, which we consider active motion, and also causes breaking of the fluctuation dissipation relation...
September 2016: Physical Review. E
Amir S Yazdi, Kamran Ghoreschi
The interleukin-1 (IL-1) family consists of several pro- or anti-inflammatory proteins, with pro-inflammatory IL-1β being its best characterized member. IL-1β is one of the most prominent mediators of inflammation resulting in fever and immune activation via binding to IL-1 receptor 1. Due to its potency, its secretion is tightly regulated. First the transcription of the biologically inactive proform is induced by TLR activation, TNF, or IL-1 receptor activation by mature IL-1α or IL-1β. For the secretion of IL-1β, inflammasome activation as second stimulus is needed...
2016: Advances in Experimental Medicine and Biology
Sadegh Yazdi, Josée R Daniel, Nicolas Large, George C Schatz, Denis Boudreau, Emilie Ringe
The internal structure of hollow AgAu nanorods created by partial galvanic replacement was manipulated reversibly and its effect on optical properties was mapped with nanometer resolution. Using the electron beam in a scanning transmission electron microscope to create solvated electrons in an encapsulated solution-filled cavity in the nanorods, Ag ions were reduced, reshaping the core of the nanoparticles without affecting the external shape. The resulting changes in plasmon-induced near-field properties were then mapped with electron energy-loss spectroscopy without disturbing the internal structure, and the results are supported by finite-difference time-domain calculations...
October 5, 2016: Nano Letters
R Palomba, A Parodi, M Evangelopoulos, S Acciardo, C Corbo, E de Rosa, I K Yazdi, S Scaria, R Molinaro, N E Toledano Furman, J You, M Ferrari, F Salvatore, E Tasciotti
Recent advances in the field of nanomedicine have demonstrated that biomimicry can further improve targeting properties of current nanotechnologies while simultaneously enable carriers with a biological identity to better interact with the biological environment. Immune cells for example employ membrane proteins to target inflamed vasculature, locally increase vascular permeability, and extravasate across inflamed endothelium. Inspired by the physiology of immune cells, we recently developed a procedure to transfer leukocyte membranes onto nanoporous silicon particles (NPS), yielding Leukolike Vectors (LLV)...
October 5, 2016: Scientific Reports
Behrooz Alizadeh Behbahani, Farideh Tabatabaei Yazdi, Fakhri Shahidi, Mohammad Ali Hesarinejad, Seyed Ali Mortazavi, Mohebbat Mohebbi
The effect of different extraction procedures on functional properties of mucilage extracted from Plantago major seed were investigated using response surface methodology. Extraction at 75°C, using 1:60 water:seed ratio at pH 6.8 was the best condition for maximum yield (15.18%), emulsion stability (67.4%), foam stability (88.4%), solubility (97.36%) and water absorption capacity (39.74g/g) of mucilage. At this optimum point, PMSM had, on average 82.85% carbohydrate, 76.79 mgGAE/gdry total phenol content, 97...
January 2, 2017: Carbohydrate Polymers
Samira Yazdi, Michael Naumann, Matthias Stein
Activation of the transcription factor NF-κB requires degradation of its physiological inhibitor IκBα in order to allow nuclear translocation of NF-kB. NF-κB activity links inflammation and carcinogenesis and makes its signaling pathway an important target for therapeutic intervention. The signal-receiving N-terminal domain (SRD) of the NF-kB inhibitor IκBα harbors the sites of post-translational modifications (Ser32 and 36) directed by the IκB kinase (IKK) complex. The SRD was originally recognized to be highly disordered, but was recently shown to possess stable secondary structural elements...
October 4, 2016: Proteins
Abolfazl Mehdizadehkashi, Kobra Tahermanesh, Abbas Fazel Anvari-Yazdi, Shahla Chaichian, Negar Azarpira, Malihe Nobakht, Seyedeh Mehr Abed, Neda Hashemi
STUDY OBJECTIVE: In general, in the context of chronic pelvic pain (CPP) and endometriosis, there is no established relationship between the severity of pain and stage of endometriosis. The aim of this study was to evaluate the pelvic peritoneum under chromoendoscopy by Scanning Electron Microscopy (SEM) as well as light microscopy with H&E staining and immunohistochemical assay in patients of CPP associated with subtle endometriosis. DESIGN: Case series study. DESIGN: classification: Canadian Task Force classification II...
September 29, 2016: Journal of Minimally Invasive Gynecology
Rowan K Leary, Anjli Kumar, Patrick J Straney, Sean M Collins, Sadegh Yazdi, Rafal E Dunin-Borkowski, Paul A Midgley, Jill E Millstone, Emilie Ringe
Catalytic and optical properties can be coupled by combining different metals into nanoscale architectures in which both the shape and the composition provide fine-tuning of functionality. Here, discrete, small Pt nanoparticles (diameter = 3-6 nm) were grown in linear arrays on Au nanoprisms, and the resulting structures are shown to retain strong localized surface plasmon resonances. Multidimensional electron microscopy and spectroscopy techniques (energy-dispersive X-ray spectroscopy, electron tomography, and electron energy-loss spectroscopy) were used to unravel their local composition, three-dimensional morphology, growth patterns, and optical properties...
September 22, 2016: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
Fatemeh Hoseyni, Ehsan Mahjoubi, Davood Zahmatkesh, Mehdi Hossein Yazdi
This research communication describes relationships between pre-weaning average daily gain (ADG) and dam parity with future productivity of dairy calves. Higher ADG before weaning has been shown to be related to greater milk production in the first lactation of Holstein calves fed milk replacer. However, data is limited on the relationship between pre-weaning ADG and first lactation performance of Holstein calves fed whole milk. Data of three hundred and thirty-two Holstein calves from 35 primiparous and 297 multiparous cows was investigated to evaluate the relationship between the dam parity and pre-weaning ADG with the first lactation performance...
September 29, 2016: Journal of Dairy Research
Ahmad Delbari, Farzane Keyghobadi, Yadollah Abolfathi Momtaz, Fariba Keyghobadi, Reza Akbari, Houman Kamranian, Mohammad Shouride Yazdi, Sayed Shahaboddin Tabatabaei, Seyed-Mohammad Fereshtehnejad
BACKGROUND: A number of studies have explored the issue of sex differences in stroke from biomedical perspective; however, there are still large gaps in the existing knowledge. The purpose of this study was to assess whether the differences in socioeconomic status and living conditions between men and women may explain the part of the sex differences in incidence and outcomes of stroke. METHODS: All stroke participants aged ≥60 years admitted in Vaseie Hospital in Sabzevar, Iran, from March 21, 2013, until March 20, 2014, were included in this study...
2016: Clinical Interventions in Aging
Dariush Minai-Tehrani, Sara Toofani, Fatemeh Yazdi, Arash Minai-Tehrani, Hmidreza Mollasalehi, Kourosh Bakhtiari Ziabari
After red blood cells lysis, hemoglobin is released to blood circulation. Hemoglobin is carried in blood by binding to haptoglobin. In normal individuals, no free hemoglobin is observed in the blood, because most of hemoglobin is in the form of haptoglobin complex. In some diseases that are accompanied by hemolysis, the amount of released hemoglobin is higher than its complementary haptoglobin. As a result, free hemoglobin appears in the blood, which is a toxic compound for these patients and may cause renal failure, hypertensive response and risk of atherogenesis...
September 16, 2016: International Journal of Biological Macromolecules
Mohammad Reza Ahmadian-Yazdi, Fatemeh Zabihi, Mehran Habibi, Morteza Eslamian
In this paper, two-step sequential spin-dip and spin-spin coating, as well as one-step spin coating, methods are used to fabricate methylammonium lead mixed-halide perovskites to study the effect of process parameters, including the choice of the solvent, annealing temperature, spin velocity, and dipping time on the characteristics of the perovskite film. Our results show that using a mixture of DMF and DMSO, with volume ratio of 1:1, as the organic solvents for PbCl2 results in the best mixed-halide perovskite because of the effective coordination between DMSO and PbCl2...
December 2016: Nanoscale Research Letters
Mahdi Jalili, Ali Salehzadeh-Yazdi, Shailendra Gupta, Olaf Wolkenhauer, Marjan Yaghmaie, Osbaldo Resendis-Antonio, Kamran Alimoghaddam
No abstract text is available yet for this article.
2016: Frontiers in Physiology
Abbas Fazel Anvari-Yazdi, Kobra Tahermanesh, Seyed Mohammad Mehdi Hadavi, Tahereh Talaei-Khozani, Mahboobeh Razmkhah, Seyedeh Mehr Abed, Maryam Sadat Mohtasebi
Magnesium (Mg)-based alloys have been extensively considered as biodegradable implant materials for orthopedic surgery. Mg and its alloys are metallic biomaterials that can degrade in the body and promote new bone formation. In this study, the corrosion behavior and cytotoxicity of Mg-Zn-Ca alloys are evaluated with adipose-derived mesenchymal stem cells (ASCs). Mg-2Zn and Mg-2Zn-xCa (x=1, 2 and 3wt.%) alloys were designated. Mg alloys were analyzed with scanning electron microscopy and potentiodynamic polarization...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Claus Garbe, Thomas K Eigentler, Jürgen Bauer, Norbert Blödorn-Schlicht, Lorenzo Cerroni, Falko Fend, Markus Hantschke, Peter Kurschat, Heinz Kutzner, Dieter Metze, Volker Mielke, Harald Preßler, Michael Reusch, Ursula Reusch, Rudolf Stadler, Michael Tronnier, Amir Yazdi, Gisela Metzler
HINTERGRUND: Die Melanomklassifikation wurde 2009 durch die AJCC revidiert. Für die Klassifizierung primärer Melanome wurde als dritte Größe neben Tumordicke und Ulzeration die Angabe der Mitoserate neu eingeführt. Gemäß der AJCC-2009-Klassifikation des Melanoms führt der Nachweis nur einer oder mehrerer dermaler Tumormitosen bei Melanomen ≤ 1,0 mm Tumordicke zu einer Umgruppierung des Tumors von T1a nach T1b. Dies erklärt, wie wichtig die Frage nach der Reproduzierbarkeit dieses neuen Parameters ist...
September 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Claus Garbe, Thomas K Eigentler, Jürgen Bauer, Norbert Blödorn-Schlicht, Lorenzo Cerroni, Falko Fend, Markus Hantschke, Peter Kurschat, Heinz Kutzner, Dieter Metze, Volker Mielke, Harald Preßler, Michael Reusch, Ursula Reusch, Rudolf Stadler, Michael Tronnier, Amir Yazdi, Gisela Metzler
BACKGROUND: In 2009, the AJCC issued a revised melanoma staging system. In addition to tumor thickness and ulceration, the mitotic rate was introduced as the third major prognostic parameter for the classification of primary cutaneous melanoma. Given that, according to the 2009 AJCC classification, the detection of one or more dermal tumor mitoses leads to an upstaging - from stage Ia to Ib - of melanomas with a tumor thickness of ≤ 1.0 mm, we set out to investigate the reproducibility of this new parameter...
September 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Khosro Sadeghniiat-Haghighi, Zohreh Yazdi, Amir-Mohammad Kazemifar
PURPOSE: Iran has a high rate of road traffic accidents. Poor quality of sleep brings about loss of attention, which is an important cause of road traffic accidents particularly in monotonous roads. The causes of poor quality of sleep in occupational drivers are multifactorial. The objective of the present study was to assess the prevalence of poor sleep quality among occupational drivers with rotating work schedules and analyze its different risk factors. METHODS: 2200 professional long-haul truck drivers who had been referred to the Occupational Health Clinic for routine education course were invited...
August 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
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