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https://www.readbyqxmd.com/read/28457662/corrigendum-re-early-recurrence-patterns-following-totally-intracorporeal-robot-assisted-radical-cystectomy-results-from-the-eau-robotic-urology-section-erus-scientific-working-group-eur-urol-2017-71-723-6
#1
Justin W Collins, Abolfazl Hosseini, Christofer Adding, Tommy Nyberg, Anthony Koupparis, Edward Rowe, Matthew Perry, Rami Issa, Martin C Schumacher, Carl Wijburg, Abdullah E Canda, Mevlana Balbay, Karel Decaestecker, Christian Schwentner, Arnulf Stenzl, Sebastian Edeling, Saša Pokupić, Fredrik D'Hondt, Alexander Mottrie, Peter N Wiklund
No abstract text is available yet for this article.
April 27, 2017: European Urology
https://www.readbyqxmd.com/read/28391975/evaluation-of-endorectal-ultrasound-erus-and-mri-for-prediction-of-circumferential-resection-margin-crm-for-rectal-cancer
#2
Catherine Tsai, Cameron Hague, Wei Xiong, Manoj Raval, Ahmer Karimuddin, Carl Brown, P Terry Phang
ERUS and MRI are used for preoperative imaging of rectal cancer. Here, we compare ERUS and MRI for accuracy of CRM prediction at mid- and distal rectal locations. In retrospective review, 20 rectal cancer patients having TME surgery had both ERUS and MRI preoperatively: 8 mid rectum and 12 in distal rectum. Predicted CRM by ERUS and MRI were compared to TME pathology. Overall, predicted CRM was 6.5 ± 3.6 mm by ERUS, 7.7 ± 5.0 mm by MRI, and 6.0 ± 4.6 mm by pathology. Overall, correlation coefficients to pathology were 0...
May 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28359551/physician-payment-schemes-and-physician-productivity-analysis-of-turkish-healthcare-reforms
#3
Burcay Erus, Ozan Hatipoglu
Following healthcare reforms in Turkey, inpatient and outpatient care provided in public hospitals more than doubled from 2003 to 2006. An important component of the reforms has been a shift from a salary based physician compensation scheme to one where fee-for-service component is dominant. The change did not only incentivize physicians to provide a higher volume of services but also encouraged them to practice full-time, rather than dual-time, in public hospitals. Lacking figures on full-time equivalent figures at hospital level, earlier research used head-counts for physician workforce and found technological change and scale economies to be important determinants...
March 8, 2017: Health Policy
https://www.readbyqxmd.com/read/28346223/early-rectal-cancer-a-choice-between-local-excision-and-transabdominal-resection-a-review-of-the-literature-and-current-guidelines
#4
Giuseppe Pappalardo, Massimo Chiaretti
INTRODUCTION: Indication for Local Excision (LE) or Trans Abdominal Resections with Total Mesorectal Excision (TAR) in Early Rectal Cancer (ERC) are still controversial. MATERIAL OF STUDY: We reviewed meta-analyses, scientific societies guidelines, randomized and controlled clinical trials from 1999 to 2016 for a total of 146,231 patients. We included in our analysis the accuracy of different tools of investigation, the reliability of the endoscopic biopsies and compared the results of the various LE and TAR...
March 27, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28113459/abnormality-detection-via-iterative-deformable-registration-and-basis-pursuit-decomposition
#5
Ke Zeng, Guray Erus, Aristeidis Sotiras, Ruseell T Shinohara, Christos Davatzikos
We present a generic method for automatic detection of abnormal regions in medical images as deviations from a normative data base. The algorithm decomposes an image, or more broadly a function defined on the image grid, into the superposition of a normal part and a residual term. A statistical model is constructed with regional sparse learning to represent normative anatomical variations among a reference population (e.g. healthy controls), in conjunction with a Markov Random Field regularization that ensures mutual consistency of the regional learning among partially overlapping image blocks...
March 7, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27881048/accuracy-of-pre-treatment-locoregional-rectal-cancer-staging-in-a-national-improvement-project
#6
Bart Op de Beeck, Peter Smeets, Freddy Penninckx, Piet Pattyn, Geert Silversmit, Elizabeth Van Eycken
BACKGROUND: The aim of this study was to assess the accuracy, particularly the predictive value, of locoregional clinical rectal cancer staging (cTN) and its variability in a national improvement project. METHODS: cTN stages and the distance between tumour and mesorectal fascia (MRF) were compared with histopathological findings in 1168 patients who underwent radical resection without neoadjuvant treatment. Data were registered prospectively from 2006 to 2014. RESULTS: Agreement between clinical and histopathological TN stages was 50%, independent of tumour location...
April 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27816299/early-recurrence-patterns-following-totally-intracorporeal-robot-assisted-radical-cystectomy-results-from-the-eau-robotic-urology-section-erus-scientific-working-group
#7
Justin W Collins, Abolfazl Hosseini, Christofer Adding, Tommy Nyberg, Anthony Koupparis, Edward Rowe, Matthew Perry, Rami Issa, Martin C Schumacher, Carl Wijburg, Abdullah E Canda, Melvin D Balbay, Karel Decaestecker, Christian Schwentner, Arnulf Stenzl, Sebastian Edeling, Saša Pokupić, Fredrik D'Hondt, Alexander Mottrie, Peter N Wiklund
Recurrence following radical cystectomy often occurs early, with >80% of recurrences occurring within the first 2 yr. Debate remains as to whether robot-assisted radical cystectomy (RARC) negatively impacts early recurrence patterns because of inadequate resection or pneumoperitoneum. We report early recurrence patterns among 717 patients who underwent RARC with intracorporeal urinary diversion at nine different institutions with a minimum follow-up of 12 mo. Clinical, pathologic, radiologic, and survival data at the latest follow-up were collected...
May 2017: European Urology
https://www.readbyqxmd.com/read/27806019/differential-associations-of-socioeconomic-status-with-global-brain-volumes-and-white-matter-lesions-in-african-american-and-white-adults-the-handls-scan-study
#8
Shari R Waldstein, Gregory A Dore, Christos Davatzikos, Leslie I Katzel, Rao Gullapalli, Stephen L Seliger, Theresa Kouo, William F Rosenberger, Guray Erus, Michele K Evans, Alan B Zonderman
OBJECTIVE: The aim of the study was to examine interactive relations of race and socioeconomic status (SES) to magnetic resonance imaging (MRI)-assessed global brain outcomes with previously demonstrated prognostic significance for stroke, dementia, and mortality. METHODS: Participants were 147 African Americans (AAs) and whites (ages 33-71 years; 43% AA; 56% female; 26% below poverty) in the Healthy Aging in Neighborhoods of Diversity across the Life Span SCAN substudy...
April 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27703783/diagnostic-potential-of-structural-neuroimaging-for-depression-from-a-multi-ethnic-community-sample
#9
Anjali Sankar, Tianhao Zhang, Bilwaj Gaonkar, Jimit Doshi, Guray Erus, Sergi G Costafreda, Lauren Marangell, Christos Davatzikos, Cynthia H Y Fu
BACKGROUND: At present, we do not have any biological tests which can contribute towards a diagnosis of depression. Neuroimaging measures have shown some potential as biomarkers for diagnosis. However, participants have generally been from the same ethnic background while the applicability of a biomarker would require replication in individuals of diverse ethnicities. AIMS: We sought to examine the diagnostic potential of the structural neuroanatomy of depression in a sample of a wide ethnic diversity...
July 2016: BJPsych Open
https://www.readbyqxmd.com/read/27489875/white-matter-hyperintensities-are-more-highly-associated-with-preclinical%C3%A2-alzheimer-s-disease-than-imaging-and-cognitive-markers-of%C3%A2-neurodegeneration
#10
Benjamin M Kandel, Brian B Avants, James C Gee, Corey T McMillan, Guray Erus, Jimit Doshi, Christos Davatzikos, David A Wolk
INTRODUCTION: Cognitive tests and nonamyloid imaging biomarkers do not consistently identify preclinical AD. The objective of this study was to evaluate whether white matter hyperintensity (WMH) volume, a cerebrovascular disease marker, is more associated with preclinical AD than conventional AD biomarkers and cognitive tests. METHODS: Elderly controls enrolled in the Alzheimer's Disease Neuroimaging Initiative (ADNI, n = 158) underwent florbetapir-PET scans, psychometric testing, neuroimaging with MRI and PET, and APOE genetic testing...
2016: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/27354104/use-of-sequential-endorectal-us-to-predict-the-tumor-response-of-preoperative-chemoradiotherapy-in-rectal-cancer
#11
Ning Li, Lizhou Dou, Yueming Zhang, Jing Jin, Guiqi Wang, Qin Xiao, Yexiong Li, Xin Wang, Hua Ren, Hui Fang, Weihu Wang, Shulian Wang, Yueping Liu, Yongwen Song
BACKGROUND AND AIMS: Accurate prediction of the response to preoperative chemoradiotherapy (CRT) potentially assists in the individualized selection of treatment. Endorectal US (ERUS) is widely used for the pretreatment staging of rectal cancer, but its use for preoperatively predicting the effects of CRT is not well evaluated because of the inflammation, necrosis, and fibrosis induced by CRT. This study assessed the value of sequential ERUS in predicting the efficacy of preoperative CRT for locally advanced rectal cancer...
March 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27353097/-assessment-of-lymph-node-status-in-rectal-cancer-by-imaging
#12
Yi Wang
Assessment of lymph node status in patients with rectal cancer is important before operation and neoadjuvant treatment because it has an influence on definition of operative plan, strategy of chemoradiotherapy and prognosis of the patients with rectal cancer. The imaging modalities that can be used to assess lymph node status include magnetic resonance imaging (MRI), endorectal ultrasonography (ERUS), multi-row detector computer tomography (MDCT), and PET-CT. The existing imaging criteria for metastatic lymph nodes in rectal cancer have not been reached...
June 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27234997/enhanced-recovery-after-robot-assisted-radical-cystectomy-eau-robotic-urology-section-scientific-working-group-consensus-view
#13
REVIEW
Justin W Collins, Hiten Patel, Christofer Adding, Magnus Annerstedt, Prokar Dasgupta, Shamim M Khan, Walter Artibani, Richard Gaston, Thierry Piechaud, James W Catto, Anthony Koupparis, Edward Rowe, Matthew Perry, Rami Issa, John McGrath, John Kelly, Martin Schumacher, Carl Wijburg, Abdullah E Canda, Meviana D Balbay, Karel Decaestecker, Christian Schwentner, Arnulf Stenzl, Sebastian Edeling, Sasa Pokupić, Michael Stockle, Stefan Siemer, Rafael Sanchez-Salas, Xavier Cathelineau, Robin Weston, Mark Johnson, Fredrik D'Hondt, Alexander Mottrie, Abolfazl Hosseini, Peter N Wiklund
CONTEXT: Radical cystectomy (RC) is associated with frequent morbidity and prolonged length of stay (LOS) irrespective of surgical approach. Increasing evidence from colorectal surgery indicates that minimally invasive surgery and enhanced recovery programmes (ERPs) can reduce surgical morbidity and LOS. ERPs are now recognised as an important component of surgical management for RC. However, there is comparatively little evidence for ERPs after robot-assisted radical cystectomy (RARC)...
October 2016: European Urology
https://www.readbyqxmd.com/read/27208378/brain-and-white-matter-hyperintensity-volumes-after-10-years-of-random-assignment-to-lifestyle-intervention
#14
Mark A Espeland, Kirk Erickson, Rebecca H Neiberg, John M Jakicic, Thomas A Wadden, Rena R Wing, Lisa Desiderio, Guray Erus, Meng-Kang Hsieh, Christos Davatzikos, Barbara J Maschak-Carey, Paul J Laurienti, Kathryn Demos-McDermott, R Nick Bryan
OBJECTIVE: Type 2 diabetes increases the accumulation of brain white matter hyperintensities and loss of brain tissue. Behavioral interventions to promote weight loss through dietary changes and increased physical activity may delay these adverse consequences. We assessed whether participation in a successful 10-year lifestyle intervention was associated with better profiles of brain structure. RESEARCH DESIGN AND METHODS: At enrollment in the Action for Health in Diabetes clinical trial, participants had type 2 diabetes, were overweight or obese, and were aged 45-76 years...
May 2016: Diabetes Care
https://www.readbyqxmd.com/read/27173368/relationship-between-apoe-genotype-and-structural-mri-measures-throughout-adulthood-in-the-study-of-health-in-pomerania-population-based-cohort
#15
M Habes, J B Toledo, S M Resnick, J Doshi, S Van der Auwera, G Erus, D Janowitz, K Hegenscheid, G Homuth, H Völzke, W Hoffmann, H J Grabe, C Davatzikos
BACKGROUND AND PURPOSE: The presence of the apolipoprotein E ε4 allele is the strongest sporadic Alzheimer disease genetic risk factor. We hypothesized that apolipoprotein E ε4 carriers and noncarriers may already differ in imaging patterns in midlife. We therefore sought to identify the effect of apolipoprotein E genotype on brain atrophy across almost the entire adult age span by using advanced MR imaging-based pattern analysis. MATERIALS AND METHODS: We analyzed MR imaging scans of 1472 participants from the Study of Health in Pomerania (22-90 years of age)...
September 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27131940/estadiaje-local-del-carcinoma-rectal-im%C3%A3-genes-de-ecograf%C3%A3-a-versus-resonancia-magn%C3%A3-tica-revisi%C3%A3-n-sistem%C3%A3-tica-de-la-literatura-y-metaan%C3%A3-lisis
#16
REVIEW
Katia F Guenaga, Jose P Otoch, Everson L A Artifon
New surgical techniques in the treatment of rectal cancer have improved survival mainly by reducing local recurrences. A preoperative staging method is required to accurately identify tumor stage and planning the appropriate treatment. MRI and ERUS are currently being used for the local staging (T stage). In this review, the accuracy of MRI and ERUS with rigid probe was compared against the gold standard of the pathological findings in the resection specimens. Five studies met the inclusion criteria and were included in this meta-analysis...
January 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/27079753/crowdsourced-estimation-of-cognitive-decline-and-resilience-in-alzheimer-s-disease
#17
Genevera I Allen, Nicola Amoroso, Catalina Anghel, Venkat Balagurusamy, Christopher J Bare, Derek Beaton, Roberto Bellotti, David A Bennett, Kevin L Boehme, Paul C Boutros, Laura Caberlotto, Cristian Caloian, Frederick Campbell, Elias Chaibub Neto, Yu-Chuan Chang, Beibei Chen, Chien-Yu Chen, Ting-Ying Chien, Tim Clark, Sudeshna Das, Christos Davatzikos, Jieyao Deng, Donna Dillenberger, Richard J B Dobson, Qilin Dong, Jimit Doshi, Denise Duma, Rosangela Errico, Guray Erus, Evan Everett, David W Fardo, Stephen H Friend, Holger Fröhlich, Jessica Gan, Peter St George-Hyslop, Satrajit S Ghosh, Enrico Glaab, Robert C Green, Yuanfang Guan, Ming-Yi Hong, Chao Huang, Jinseub Hwang, Joseph Ibrahim, Paolo Inglese, Anandhi Iyappan, Qijia Jiang, Yuriko Katsumata, John S K Kauwe, Arno Klein, Dehan Kong, Roland Krause, Emilie Lalonde, Mario Lauria, Eunjee Lee, Xihui Lin, Zhandong Liu, Julie Livingstone, Benjamin A Logsdon, Simon Lovestone, Tsung-Wei Ma, Ashutosh Malhotra, Lara M Mangravite, Taylor J Maxwell, Emily Merrill, John Nagorski, Aishwarya Namasivayam, Manjari Narayan, Mufassra Naz, Stephen J Newhouse, Thea C Norman, Ramil N Nurtdinov, Yen-Jen Oyang, Yudi Pawitan, Shengwen Peng, Mette A Peters, Stephen R Piccolo, Paurush Praveen, Corrado Priami, Veronica Y Sabelnykova, Philipp Senger, Xia Shen, Andrew Simmons, Aristeidis Sotiras, Gustavo Stolovitzky, Sabina Tangaro, Andrea Tateo, Yi-An Tung, Nicholas J Tustison, Erdem Varol, George Vradenburg, Michael W Weiner, Guanghua Xiao, Lei Xie, Yang Xie, Jia Xu, Hojin Yang, Xiaowei Zhan, Yunyun Zhou, Fan Zhu, Hongtu Zhu, Shanfeng Zhu
Identifying accurate biomarkers of cognitive decline is essential for advancing early diagnosis and prevention therapies in Alzheimer's disease. The Alzheimer's disease DREAM Challenge was designed as a computational crowdsourced project to benchmark the current state-of-the-art in predicting cognitive outcomes in Alzheimer's disease based on high dimensional, publicly available genetic and structural imaging data. This meta-analysis failed to identify a meaningful predictor developed from either data modality, suggesting that alternate approaches should be considered for prediction of cognitive performance...
June 2016: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/27046847/abnormality-detection-via-iterative-deformable-registration-and-basis-pursuit-decomposition
#18
Ke Zeng, Guray Erus, Aristeidis Sotiras, Russell T Shinohara, Christos Davatzikos
We present a generic method for automatic detection of abnormal regions in medical images as deviations from a normative data base. The algorithm decomposes an image, or more broadly a function defined on the image grid, into the superposition of a normal part and a residual term. A statistical model is constructed with regional sparse learning to represent normative anatomical variations among a reference population (e.g., healthy controls), in conjunction with a Markov random field regularization that ensures mutual consistency of the regional learning among partially overlapping image blocks...
August 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27045845/advanced-brain-aging-relationship-with-epidemiologic-and-genetic-risk-factors-and-overlap-with-alzheimer-disease-atrophy-patterns
#19
M Habes, D Janowitz, G Erus, J B Toledo, S M Resnick, J Doshi, S Van der Auwera, K Wittfeld, K Hegenscheid, N Hosten, R Biffar, G Homuth, H Völzke, H J Grabe, W Hoffmann, C Davatzikos
We systematically compared structural imaging patterns of advanced brain aging (ABA) in the general-population, herein defined as significant deviation from typical BA to those found in Alzheimer disease (AD). The hypothesis that ABA would show different patterns of structural change compared with those found in AD was tested via advanced pattern analysis methods. In particular, magnetic resonance images of 2705 participants from the Study of Health in Pomerania (aged 20-90 years) were analyzed using an index that captures aging atrophy patterns (Spatial Pattern of Atrophy for Recognition of BA (SPARE-BA)), and an index previously shown to capture atrophy patterns found in clinical AD (Spatial Patterns of Abnormality for Recognition of Early Alzheimer's Disease (SPARE-AD))...
April 5, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/26982085/structural-brain-abnormalities-in-youth-with-psychosis-spectrum-symptoms
#20
Theodore D Satterthwaite, Daniel H Wolf, Monica E Calkins, Simon N Vandekar, Guray Erus, Kosha Ruparel, David R Roalf, Kristin A Linn, Mark A Elliott, Tyler M Moore, Hakon Hakonarson, Russell T Shinohara, Christos Davatzikos, Ruben C Gur, Raquel E Gur
IMPORTANCE: Structural brain abnormalities are prominent in psychotic disorders, including schizophrenia. However, it is unclear when aberrations emerge in the disease process and if such deficits are present in association with less severe psychosis spectrum (PS) symptoms in youth. OBJECTIVE: To investigate the presence of structural brain abnormalities in youth with PS symptoms. DESIGN, SETTING, AND PARTICIPANTS: The Philadelphia Neurodevelopmental Cohort is a prospectively accrued, community-based sample of 9498 youth who received a structured psychiatric evaluation...
May 1, 2016: JAMA Psychiatry
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