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https://www.readbyqxmd.com/read/29225302/role-of-surgery-in-the-treatment-of-masaoka-stage-iva-thymoma
#1
Erkan Kaba, Berker Ozkan, Suat Erus, Salih Duman, Berk Cimenoglu, Alper Toker
PURPOSE: To analyze the role of surgery in patients with Masaoka stage IVa thymoma treated with multimodality therapy. METHODS: Of 191 patients undergoing surgery for thymoma in our department between January 2002 and December 2015, 39 (20.4%) had Masaoka stage IVa. Histopathological tumor type, myasthenic status of the Osserman-Genkins score, Masaoka stage at the first surgery, neoadjuvant treatment, number and type of surgeries, and survival rates were recorded...
December 8, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29186619/multisite-machine-learning-analysis-provides-a-robust-structural-imaging-signature-of-schizophrenia-detectable-across-diverse-patient-populations-and-within-individuals
#2
Martin Rozycki, Theodore D Satterthwaite, Nikolaos Koutsouleris, Guray Erus, Jimit Doshi, Daniel H Wolf, Yong Fan, Raquel E Gur, Ruben C Gur, Eva M Meisenzahl, Chuanjun Zhuo, Hong Ying, Hao Yan, Weihua Yue, Dai Zhang, Christos Davatzikos
Past work on relatively small, single-site studies using regional volumetry, and more recently machine learning methods, has shown that widespread structural brain abnormalities are prominent in schizophrenia. However, to be clinically useful, structural imaging biomarkers must integrate high-dimensional data and provide reproducible results across clinical populations and on an individual person basis. Using advanced multi-variate analysis tools and pooled data from case-control imaging studies conducted at 5 sites (941 adult participants, including 440 patients with schizophrenia), a neuroanatomical signature of patients with schizophrenia was found, and its robustness and reproducibility across sites, populations, and scanners, was established for single-patient classification...
November 24, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29178092/-updates-of-2017-esmo-guideline-for-rectal-cancer
#3
Gong Chen, Yi Wang
Compared with the 2013 version, the basic strategies of diagnosis and treatment for rectal cancer in the 2017 version guideline remain the same. These strategies include accurate local staging approaches which combines digital rectal examination, endorectal ultrasound (ERUS), and high resolution pelvic MRI, and local recurrence risk grading system which combines tumor location/distance, T staging, N staging, EMVI (extramural vascular invasion) and MRF(mesorectal fascia). And personalized therapeutic principle based on the above local risk grading...
November 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29113193/value-of-endorectal-ultrasonography-in-measuring-the-extent-of-mesorectal-invasion-and-substaging-of-t3-stage-rectal-cancer
#4
Guangxi Zhong, Yi Xiao, Weixun Zhou, Weidong Pan, Qingli Zhu, Jing Zhang, Yuxin Jiang
The present study aimed to determine the value of endorectal ultrasound (ERUS) and magnetic resonance imaging (MRI) for T3 rectal cancer, and substaging of T3 rectal cancer by measuring the extent of mesorectal invasion (EMI). The clinical data of patients with rectal cancer who were admitted to the general surgical department of Peking Union Medical College Hospital (Beijing, China) were reviewed and analyzed. Two ultrasound practitioners independently measured the EMI on ERUS, and a radiologist measured the EMI on MRI...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29107121/longitudinally-and-inter-site-consistent-multi-atlas-based-parcellation-of-brain-anatomy-using-harmonized-atlases
#5
Guray Erus, Jimit Doshi, Yang An, Dimitris Verganelakis, Susan M Resnick, Christos Davatzikos
As longitudinal and multi-site studies become increasingly frequent in neuroimaging, maintaining longitudinal and inter-scanner consistency of brain parcellation has become a major challenge due to variation in scanner models and/or image acquisition protocols across scanners and sites. We present a new automated segmentation method specifically designed to achieve a consistent parcellation of anatomical brain structures in such heterogeneous datasets. Our method combines a site-specific atlas creation strategy with a state-of-the-art multi-atlas anatomical label fusion framework...
November 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/29080396/neurobiological-support-to-the-diagnosis-of-adhd-in-stimulant-na%C3%A3-ve-adults-pattern-recognition-analyses-of-mri-data
#6
T M Chaim-Avancini, J Doshi, M V Zanetti, G Erus, M A Silva, F L S Duran, M Cavallet, M H Serpa, S C Caetano, M R Louza, C Davatzikos, G F Busatto
OBJECTIVE: In adulthood, the diagnosis of attention-deficit/hyperactivity disorder (ADHD) has been subject of recent controversy. We searched for a neuroanatomical signature associated with ADHD spectrum symptoms in adults by applying, for the first time, machine learning-based pattern classification methods to structural MRI and diffusion tensor imaging (DTI) data obtained from stimulant-naïve adults with childhood-onset ADHD and healthy controls (HC). METHOD: Sixty-seven ADHD patients and 66 HC underwent high-resolution T1-weighted and DTI acquisitions...
October 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28933457/robotic-segmentectomy-far-beyond-choice
#7
EDITORIAL
Suat Erus, Serhan Tanju
No abstract text is available yet for this article.
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28844834/what-makes-new-ischemic-lesions-symptomatic-after-aortic-valve-replacement
#8
Ronen R Leker, Steven R Messé, Guray Erus, Michel Bilello, Molly Fanning, Michael Acker, Allie Massaro, Scott E Kasner, Thomas Floyd
BACKGROUND: Acute cerebral infarctions on diffusion-weighted magnetic resonance imaging (MRI) are common after cardiothoracic surgery. However, most are asymptomatic and we aimed to identify features associated with clinical stroke symptoms. METHODS: Patients over 65 years of age undergoing surgical aortic valve replacement (AVR) for calcific stenosis were prospectively recruited (N = 196). All patients underwent neurological evaluation preoperatively and on postoperative days 1, 3, and 7, and MRI on planned postoperative day 5...
August 24, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28836241/-standardized-development-of-transanal-endoscopic-microsurgery
#9
Guole Lin
Transanal endoscopic microsurgery (TEM) is currently the only one-port system in endoscopic surgery, which a direct endoluminal approach can lead to the target organ through a natural opening of human body. TEM has been applied in colorectal surgery for over 3 decades. Compared with radical surgery, TEM has the advantages, such as quicker recovery, shorter hospital stay and fewer complications. One perfect TEM surgical system, which mainly consists of three parts, namely peculiar rectoscope for surgery, special surgical instruments and imaging system, is the foundation of standardized development of TEM...
August 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28826419/state-dependent-microstructural-white-matter-changes-in-drug-na%C3%A3-ve-patients-with-first-episode-psychosis
#10
M H Serpa, J Doshi, G Erus, T M Chaim-Avancini, M Cavallet, M T van de Bilt, P C Sallet, W F Gattaz, C Davatzikos, G F Busatto, M V Zanetti
BACKGROUND: Diffusion tensor imaging (DTI) studies have consistently shown white matter (WM) microstructural abnormalities in schizophrenia. Whether or not such alterations could vary depending on clinical status (i.e. acute psychosis v. remission) remains to be investigated. METHODS: Twenty-five treatment-naïve first-episode psychosis (FEP) patients and 51 healthy-controls (HC) underwent MRI scanning at baseline. Twenty-one patients were re-scanned as soon as they achieved sustained remission of symptoms; 36 HC were also scanned twice...
August 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28755790/correlation-between-disease-activity-and-endorectal-ultrasound-findings-of-chronic-radiation-proctitis
#11
Fei Cao, Teng-Hui Ma, Guang-Jian Liu, Yan-Lin Wen, Huai-Ming Wang, Ying-Yi Kuang, Si Qin, Xiao-Yin Liu, Bin-Jie Huang, Lei Wang
The aim of this study was to summarize the imaging features of chronic radiation proctitis (CRP) on endorectal ultrasound (ERUS) and investigate the value of ERUS in the evaluation of disease activity. 40 CRP patients and 30 control patients were investigated by ERUS. Rectal wall thickness and layers, ulcers and rectovaginal fistulas were evaluated by B-mode ultrasound. Power Doppler imaging was used to evaluate the vascularity of the rectal wall using a semiquantitative score. Disease activity was calculated according to the National Cancer Institute Common Terminology Criteria for Adverse Events 4...
July 26, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28686425/source-receptor-relationship-analysis-of-the-atmospheric-deposition-of-pahs-subject-to-long-range-transport-in-northeast-asia
#12
Yayoi Inomata, Mizuo Kajino, Keiichi Sato, Junichi Kurokawa, Ning Tang, Toshimasa Ohara, Kazuichi Hayakawa, Hiromasa Ueda
The source-receptor relationship analysis of PAH deposition in Northeast Asia was investigated using an Eulerian regional-scale aerosol chemical transport model. Dry deposition (DD) of PAH was controlled by wind flow patterns, whereas wet deposition (WD) depended on precipitation in addition to wind flow patterns. The contribution of WD was approximately 50-90% of the total deposition, except during winter in Northern China (NCHN) and Eastern Russia (ERUS) because of the low amount of precipitation. The amount of PAH deposition showed clear seasonal variation and was high in winter and low in summer in downwind (South Korea, Japan) and oceanic-receptor regions...
July 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28685744/endorectal-fusion-imaging-a-description-of-a-new-technique
#13
Andre Ignee, Yi Dong, Gudrun Schuessler, Ulrich Baum, Christoph F Dietrich
BACKGROUND: Fusion imaging is an accepted method in abdominal imaging allowing a simultaneous display of reference imaging with a live ultrasound (US) investigation. For prostate cancer, promising results have been published for endorectal US (ERUS)-guided biopsy of suspicious lesions in magnetic resonance imaging (MRI). To our knowledge, no other indication for the fusion of ERUS with MRI has been reported so far. METHODS: We report on three patients scheduled for ERUS due to anorectal fistulae after treatment (n = 2) or rectal carcinoma (n = 1), which were scheduled for real-time virtual onography (RVS), a method for the fusion of MRI imaging with US...
July 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28457662/corrigendum-re-early-recurrence-patterns-following-totally-intracorporeal-robot-assisted-radical-cystectomy-results-from-the-eau-robotic-urology-section-erus-scientific-working-group-eur-urol-2017-71-723-6
#14
Justin W Collins, Abolfazl Hosseini, Christofer Adding, Tommy Nyberg, Anthony Koupparis, Edward Rowe, Matthew Perry, Rami Issa, Martin C Schumacher, Carl Wijburg, Abdullah E Canda, Mevlana Balbay, Karel Decaestecker, Christian Schwentner, Arnulf Stenzl, Sebastian Edeling, Saša Pokupić, Fredrik D'Hondt, Alexander Mottrie, Peter N Wiklund
No abstract text is available yet for this article.
April 27, 2017: European Urology
https://www.readbyqxmd.com/read/28391975/evaluation-of-endorectal-ultrasound-erus-and-mri-for-prediction-of-circumferential-resection-margin-crm-for-rectal-cancer
#15
COMPARATIVE STUDY
Catherine Tsai, Cameron Hague, Wei Xiong, Manoj Raval, Ahmer Karimuddin, Carl Brown, P Terry Phang
ERUS and MRI are used for preoperative imaging of rectal cancer. Here, we compare ERUS and MRI for accuracy of CRM prediction at mid- and distal rectal locations. In retrospective review, 20 rectal cancer patients having TME surgery had both ERUS and MRI preoperatively: 8 mid rectum and 12 in distal rectum. Predicted CRM by ERUS and MRI were compared to TME pathology. Overall, predicted CRM was 6.5 ± 3.6 mm by ERUS, 7.7 ± 5.0 mm by MRI, and 6.0 ± 4.6 mm by pathology. Overall, correlation coefficients to pathology were 0...
May 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28359551/physician-payment-schemes-and-physician-productivity-analysis-of-turkish-healthcare-reforms
#16
Burcay Erus, Ozan Hatipoglu
Following healthcare reforms in Turkey, inpatient and outpatient care provided in public hospitals more than doubled from 2003 to 2006. An important component of the reforms has been a shift from a salary based physician compensation scheme to one where fee-for-service component is dominant. The change did not only incentivize physicians to provide a higher volume of services but also encouraged them to practice full-time, rather than dual-time, in public hospitals. Lacking figures on full-time equivalent figures at hospital level, earlier research used head-counts for physician workforce and found technological change and scale economies to be important determinants...
May 2017: Health Policy
https://www.readbyqxmd.com/read/28346223/early-rectal-cancer-a-choice-between-local-excision-and-transabdominal-resection-a-review-of-the-literature-and-current-guidelines
#17
Giuseppe Pappalardo, Massimo Chiaretti
INTRODUCTION: Indication for Local Excision (LE) or Trans Abdominal Resections with Total Mesorectal Excision (TAR) in Early Rectal Cancer (ERC) are still controversial. MATERIAL OF STUDY: We reviewed meta-analyses, scientific societies guidelines, randomized and controlled clinical trials from 1999 to 2016 for a total of 146,231 patients. We included in our analysis the accuracy of different tools of investigation, the reliability of the endoscopic biopsies and compared the results of the various LE and TAR...
March 27, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28113459/abnormality-detection-via-iterative-deformable-registration-and-basis-pursuit-decomposition
#18
Ke Zeng, Guray Erus, Aristeidis Sotiras, Ruseell T Shinohara, Christos Davatzikos
We present a generic method for automatic detection of abnormal regions in medical images as deviations from a normative data base. The algorithm decomposes an image, or more broadly a function defined on the image grid, into the superposition of a normal part and a residual term. A statistical model is constructed with regional sparse learning to represent normative anatomical variations among a reference population (e.g. healthy controls), in conjunction with a Markov Random Field regularization that ensures mutual consistency of the regional learning among partially overlapping image blocks...
March 7, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27881048/accuracy-of-pre-treatment-locoregional-rectal-cancer-staging-in-a-national-improvement-project
#19
MULTICENTER STUDY
Bart Op de Beeck, Peter Smeets, Freddy Penninckx, Piet Pattyn, Geert Silversmit, Elizabeth Van Eycken
BACKGROUND: The aim of this study was to assess the accuracy, particularly the predictive value, of locoregional clinical rectal cancer staging (cTN) and its variability in a national improvement project. METHODS: cTN stages and the distance between tumour and mesorectal fascia (MRF) were compared with histopathological findings in 1168 patients who underwent radical resection without neoadjuvant treatment. Data were registered prospectively from 2006 to 2014. RESULTS: Agreement between clinical and histopathological TN stages was 50%, independent of tumour location...
April 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27816299/early-recurrence-patterns-following-totally-intracorporeal-robot-assisted-radical-cystectomy-results-from-the-eau-robotic-urology-section-erus-scientific-working-group
#20
Justin W Collins, Abolfazl Hosseini, Christofer Adding, Tommy Nyberg, Anthony Koupparis, Edward Rowe, Matthew Perry, Rami Issa, Martin C Schumacher, Carl Wijburg, Abdullah E Canda, Melvin D Balbay, Karel Decaestecker, Christian Schwentner, Arnulf Stenzl, Sebastian Edeling, Saša Pokupić, Fredrik D'Hondt, Alexander Mottrie, Peter N Wiklund
Recurrence following radical cystectomy often occurs early, with >80% of recurrences occurring within the first 2 yr. Debate remains as to whether robot-assisted radical cystectomy (RARC) negatively impacts early recurrence patterns because of inadequate resection or pneumoperitoneum. We report early recurrence patterns among 717 patients who underwent RARC with intracorporeal urinary diversion at nine different institutions with a minimum follow-up of 12 mo. Clinical, pathologic, radiologic, and survival data at the latest follow-up were collected...
May 2017: European Urology
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