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https://www.readbyqxmd.com/read/28812878/nanomechanical-imaging-of-the-diffusion-of-fullerene-into-conjugated-polymer
#1
Dong Wang, Ken Nakajima, Feng Liu, Shaowei Shi, Thomas P Russell
The large Young's modulus difference between chemically modified fullerene (PCBM) and a conjugated polymer was used to nanomechanically map the diffusion of PCBM into PTB7, a high efficiency low band gap conjugated polymer. The sharp tip in nanomechanical atomic force microscopy (AFM) ensures a high-resolution nanomechanical characterization of the diffusion front, with the intrinsic benefits of revealing the mechanical properties of the mixtures. Localized structure changes induced by diffusion were investigated by grazing incidence x-ray diffraction methods...
August 16, 2017: ACS Nano
https://www.readbyqxmd.com/read/28812849/global-health-in-the-anthropocene-moving-beyond-resilience-and-capitalism-comment-on-health-promotion-in-an-age-of-normative-equity-and-rampant-inequality
#2
Remco van de Pas
There has been much reflection on the need for a new understanding of global health and the urgency of a paradigm shift to address global health issues. A crucial question is whether this is still possible in current modes of global governance based on capitalist values. Four reflections are provided. (1) Ecological -centered values must become central in any future global health framework. (2) The objectives of 'sustainability' and 'economic growth' present a profound contradiction. (3) The resilience discourse maintains a gridlock in the functioning of the global health system...
December 24, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812820/defining-integrated-knowledge-translation-and-moving-forward-a-response-to-recent-commentaries
#3
Anita Kothari, Chris McCutcheon, Ian D Graham
No abstract text is available yet for this article.
February 8, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812819/advancing-public-health-on-the-changing-global-trade-and-investment-agenda-comment-on-the-trans-pacific-partnership-is-it-everything-we-feared-for-health
#4
Anne Marie Thow, Deborah Gleeson
Concerns regarding the Trans-Pacific Partnership (TPP) have raised awareness about the negative public health impacts of trade and investment agreements. In the past decade, we have learned much about the implications of trade agreements for public health: reduced equity in access to health services; increased flows of unhealthy commodities; limits on access to medicines; and constrained policy space for health. Getting health on the trade agenda continues to prove challenging, despite some progress in moving towards policy coherence...
September 28, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812818/assessing-the-health-impact-of-trade-a-call-for-an-expanded-research-agenda-comment-on-the-trans-pacific-partnership-is-it-everything-we-feared-for-health
#5
Courtney McNamara
Labonté et al provide an insightful analysis of the Trans-Pacific Partnership (TPP) and its impact on a selection of important health determinants. Their work confirms concerns raised by previous analyses of leaked drafts and offers governments serious and timely reasons to carefully consider provisions of the agreement prior to moving forward with ratification. It also contributes more generally to a growing literature focused on identifying the health impacts of trade. This commentary uses the authors' analysis as a starting point to reflect on two interrelated issues relevant both for taking seriously one of the article's main recommendations and future work in the area of trade and health...
September 14, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812616/legacy-effects-of-developmental-stages-determine-the-functional-role-of-predators
#6
Volker H W Rudolf, B G Van Allen
Predators are instrumental in structuring natural communities and ecosystem processes. The strong effects of predators are often attributed to their high trophic position in the food web. However, most predators have to grow and move up the food chain before reaching their final trophic position, and during this developmental process their traits, interactions and abundances change. Here, we show that this process of 'moving up' the food chain during development strongly determines the ecological role of a predator...
January 13, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812154/robotic-versus-laparoscopic-versus-open-colorectal-surgery-towards-defining-criteria-to-the-right-choice
#7
Matthew Zelhart, Andreas M Kaiser
OBJECTIVE: Analysis of various parameters related to the patient, the disease, and the needed surgical maneuvers to develop guidance for preoperative selection of the appropriate and the best approach for a given patient. Rapid advances in minimally invasive surgical technology are fascinating and challenging alike. It can be difficult for surgeons to keep up with new modalities that come on to the market place and to assess their true value, i.e., distinguish between fashionable trends versus scientific evidence...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28812153/establishing-the-learning-curve-of-transanal-minimally-invasive-surgery-for-local-excision-of-rectal-neoplasms
#8
Lawrence Lee, Justin Kelly, George J Nassif, Deborah Keller, Teresa C Debeche-Adams, Paul A Mancuso, John R Monson, Matthew R Albert, Sam B Atallah
INTRODUCTION: Transanal minimally invasive surgery (TAMIS) is an endoscopic operating platform for local excision of rectal neoplasms. However, it may be technically demanding, and its learning curve has yet to be adequately defined. The objective of this study was to determine the number of TAMIS procedures for the local excision of rectal neoplasm required to reach proficiency. METHODS AND PROCEDURES: All TAMIS cases performed from 07/2009 to 12/2016 at a single high-volume tertiary care institution for local excision of benign and malignant rectal neoplasia were identified from a prospective database...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28812061/behavioral-comorbidities-and-drug-treatments-in-a-zebrafish-scn1lab-model-of-dravet-syndrome
#9
Brian P Grone, Tiange Qu, Scott C Baraban
Loss-of-function mutations in SCN1A cause Dravet syndrome (DS), a catastrophic childhood epilepsy in which patients experience comorbid behavioral conditions, including movement disorders, sleep abnormalities, anxiety, and intellectual disability. To study the functional consequences of voltage-gated sodium channel mutations, we use zebrafish with a loss-of-function mutation in scn1lab, a zebrafish homolog of human SCN1A. Homozygous scn1lab(s552/s552) mutants exhibit early-life seizures, metabolic deficits, and early death...
July 2017: ENeuro
https://www.readbyqxmd.com/read/28811914/the-impact-of-transforming-care-on-the-care-and-safety-of-patients-with-intellectual-disabilities-and-forensic-needs
#10
John L Taylor, Iain McKinnon, Ian Thorpe, Bruce T Gillmer
NHS England recently published a national plan to develop community services for people with intellectual disabilities and autism who display challenging behaviour by using resources from the closure of a large number of hospital beds. An ambitious timescale has been set to implement this plan. The bed closure programme is moving ahead rapidly, but there has been little progress in developing community services to support it. This paper discusses the impact of the gap between policy and practice on the care and safety of patients with intellectual disabilities and forensic needs who form a distinct subgroup of the target population and are being disproportionately affected by this government policy...
August 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28811869/pro-and-antioxidant-functions-of-the-peroxisome-mitochondria-connection-and-its-impact-on-aging-and-disease
#11
REVIEW
Amparo Pascual-Ahuir, Sara Manzanares-Estreder, Markus Proft
Peroxisomes and mitochondria are the main intracellular sources for reactive oxygen species. At the same time, both organelles are critical for the maintenance of a healthy redox balance in the cell. Consequently, failure in the function of both organelles is causally linked to oxidative stress and accelerated aging. However, it has become clear that peroxisomes and mitochondria are much more intimately connected both physiologically and structurally. Both organelles share common fission components to dynamically respond to environmental cues, and the autophagic turnover of both peroxisomes and mitochondria is decisive for cellular homeostasis...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28811824/preparation-of-galla-chinensis-oral-solution-as-well-as-its-stability-safety-and-antidiarrheal-activity-evaluation
#12
Yi Yang, Huihui Luo, Xu Song, Li Yu, Juan Xie, Jiajie Yang, Renyong Jia, Juchun Lin, Yuanfeng Zou, Lixia Li, Lizi Yin, Changliang He, Xiaoxia Liang, Guizhou Yue, Zhongqiong Yin
BACKGROUND OF THE STUDY: As a widely used traditional medicine, Galla Chinensis is rich in tannins. However, there are few detailed studies about pharmaceutical preparations of Galla Chinensis tannin extract (GTE). In the present experiments, for better application and to investigate the possibility that Galla Chinensis tannin extract can be used as an antidiarrheal drug, we prepared Galla Chinensis oral solution (GOS). MATERIALS AND METHODS: GOS was prepared with GTE, and its physicochemical and microbiological stability was evaluated...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28811819/adaptive-resource-utilization-prediction-system-for-infrastructure-as-a-service-cloud
#13
Qazi Zia Ullah, Shahzad Hassan, Gul Muhammad Khan
Infrastructure as a Service (IaaS) cloud provides resources as a service from a pool of compute, network, and storage resources. Cloud providers can manage their resource usage by knowing future usage demand from the current and past usage patterns of resources. Resource usage prediction is of great importance for dynamic scaling of cloud resources to achieve efficiency in terms of cost and energy consumption while keeping quality of service. The purpose of this paper is to present a real-time resource usage prediction system...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28811182/implementing-sustainable-data-collection-for-a-cardiac-outcomes-registry-in-an-australian-public-hospital
#14
Nicholas Cox, Angela Brennan, Diem Dinh, Rita Brien, Kath Cowie, Dion Stub, Christopher M Reid, Jeffrey Lefkovits
BACKGROUND: Clinical outcome registries are an increasingly vital component of ensuring quality and safety of patient care. However, Australian hospitals rarely have additional resources or the capacity to fund the additional staff time to complete the task of data collection and entry. At the same time, registry funding models do not support staff for the collection of data at the site but are directed towards the central registry tasks of data reporting, managing and quality monitoring...
March 12, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28811151/proposed-model-for-translational-research-at-a-teaching-intensive-college-of-pharmacy
#15
Erin Ulrich, Sarah Grady, Jacqueline Vonderhaar, Andrew Ruplin
BACKGROUND: Many American colleges of pharmacy are small, private, teaching institutions. Faculty are required to maintain a research agenda, although the publication quota is less compared with their publicly funded college of pharmacy peers. Faculty at these smaller schools conduct research with very little internal or external funding. This tends to lead to smaller, less impactful research findings. Translational research is becoming popular for research faculty as it bridges theory to practice...
August 8, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28810977/moving-beyond-accidental-leadership-a-graduate-medical-education-leadership-curriculum-needs-assessment
#16
Joshua D Hartzell, Clifton E Yu, Brian M Cohee, Michael R Nelson, Ramey L Wilson
BACKGROUND: Despite calls for greater physician leadership, few medical schools, and graduate medical education programs provide explicit training on the knowledge, skills, and attitudes necessary to be an effective physician leader. Rather, most leaders develop through what has been labeled "accidental leadership." A survey was conducted at Walter Reed to define the current status of leadership development and determine what learners and faculty perceived as key components of a leadership curriculum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810960/talk-to-the-hand-u-s-army-biophysical-testing
#17
William R Santee, Adam W Potter, Karl E Friedl
BACKGROUND: Many people are unaware of the science underlying the biophysical properties of Soldier clothing and personal protective equipment, yet there is a well-refined biomedical methodology initiated by Army physiologists in World War II. This involves a methodical progression of systematic material testing technologies, computer modeling, and human testing that enables more efficient development and rapid evaluation of new concepts for Soldier health and performance. Sophisticated manikins that sweat and move are a central part of this testing continuum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810866/the-development-of-an-ivermectin-based-attractive-toxic-sugar-bait-atsb-to-target-anopheles-arabiensis
#18
Frank Chelestino Tenywa, Athumani Kambagha, Adam Saddler, Marta Ferreira Maia
BACKGROUND: An increasing number of countries in sub-Saharan Africa are moving towards malaria-elimination, mostly thanks to successful vector control campaigns. However, elimination has proven challenging, resulting in the persistence of malaria transmission. It is now accepted that in order to eliminate malaria, new complementary vector control approaches must be developed. This study describes the development of a sugar-baited resting place containing a toxic dose of ivermectin for the control of Anopheles arabiensis...
August 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28810791/a-general-rotating-hard-sphere-model-applied-to-the-transport-properties-of-a-low-density-gas
#19
Michael Meanwell, Mark Thachuk
A general, spherical, rigid model is introduced for describing rotating and translating particles. The model contains a parameter, which we label γ, that smoothly interpolates between the smooth hard sphere (γ = 0) and rough hard sphere (γ = 1) limits. Analytic expressions for transport coefficients are determined for the general model in the low density limit and compared with those for the smooth and rough hard sphere cases. While the diffusion constant decreases monotonically on moving from the smooth to the rough sphere limits, both the viscosity and thermal conductivity first decrease and then increase, thereby producing a minimum between the two limits...
August 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28810760/a-thermodynamic-model-of-contact-angle-hysteresis
#20
Lasse Makkonen
When a three-phase contact line moves along a solid surface, the contact angle no longer corresponds to the static equilibrium angle but is larger when the liquid is advancing and smaller when the liquid is receding. The difference between the advancing and receding contact angles, i.e., the contact angle hysteresis, is of paramount importance in wetting and capillarity. For example, it determines the magnitude of the external force that is required to make a drop slide on a solid surface. Until now, fundamental origin of the contact angle hysteresis has been controversial...
August 14, 2017: Journal of Chemical Physics
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