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https://www.readbyqxmd.com/read/29236279/the-maxillary-nerve-block-for-in-office-hybrid-balloon-sinus-dilation-procedures-a-preliminary-study
#1
Gary J Nishioka
Transitioning of rhinologic procedures from the operating room to the office setting in selected patients is a rising trend. An effective pain-control, patient-preparation protocol is essential, especially with advanced in-office rhinologic procedures such as hybrid balloon sinus dilation (BSD), in which other procedures such as ethmoidectomy, turbinate reduction, and other procedures are concomitantly performed. A regimen using oral sedation, topical tetracaine gel, topical tetracaine/epinephrine-soaked cottonoid packs, and intranasal local infiltrative anesthesia can vary significantly in effectiveness and be suboptimal at times (as determined by using treated patients as historical controls)...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29236276/5-ht7-receptors-are-over-expressed-in-patients-with-nasal-polyps
#2
Muhammed Yayla, Zekai Halici, Duygu Kose, Arzu Tatar, Mustafa Sitki Gozeler
Nasal polyposis (NP) is an inflammatory disease of the paranasal sinuses and nasal cavity. The primary purpose of our study is to determine the expression of 5-HT7 receptors both in nasal polyps and in healthy tissue in the nasal cavity. The subsequent aim is to compare the expression of 5-HT7 receptors in patients with NP and in inferior turbinate tissue (control). The study included 60 participants (40 with NP and 20 controls) aged 35 to 62 years. Nasal polyp samples were collected from all patients and relative 5-HT7 receptor expression analyses were performed...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29227043/the-association-of-air-pollutants-and-allergic-and-nonallergic-rhinitis-in-chronic-rhinosinusitis
#3
Leila J Mady, Hannah L Schwarzbach, John A Moore, Robert M Boudreau, Thomas M Kaffenberger, Thomas J Willson, Stella E Lee
BACKGROUND: There has been little investigation regarding air quality and rhinitis in the pathophysiology of upper airway disease. In this study, we assessed the impact of inhalant pollutants (particulate matter 2.5 [PM2.5 ] and black carbon [BC]) on allergic rhinitis and chronic rhinosinusitis (CRS) disease severity. METHODS: CRS patients with nasal polyps (CRSwNP) and without polyps (CRSsNP) were identified. Spatial modeling from pollutant monitoring sites was used to estimate exposures for patients meeting the inclusion criteria (total, n = 125; CRSsNP, n = 67; CRSsNP, n = 58)...
December 11, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29224044/pattern-of-care-and-impact-of-prognostic-factors-on-the-outcome-of-head-and-neck-extramedullary-plasmacytoma-a-systematic-review-and-individual-patient-data-analysis-of-315-cases
#4
Bhanuprasad Venkatesulu, Supriya Mallick, Prashanth Giridhar, Ashish Dutt Upadhyay, Goura K Rath
INTRODUCTION: Head and neck extramedullary plasmacytoma is a rare localized plasma cell neoplasm. We intended to perform this review of the published literature to assess the demographic profile, pattern of care and survival outcomes. METHODS: Two authors independently searched PubMed, Google search and Cochrane library for eligible studies from 1950 till July 1, 2016, published in English language. RESULTS: Median age of the cohort was 57 years (range 11-85)...
December 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29219959/primary-orbital-ewing-sarcoma-family-of-tumors-a-study-of-12-cases
#5
S Kaliki, S G Rathi, V A R Palkonda
PurposeThe purpose of this study is to discuss the clinical presentation, management, and outcomes of patients with primary orbital Ewing sarcoma family of tumors (ESFTs).Patients and methodsRetrospective study of 12 patients with biopsy-proven primary orbital ESFT.ResultsThe mean age at presentation of primary orbital ESFT was 12 years (median, 8 years; range, 5 months to 28 years). There were seven (58%) females and five (42%) males. The presenting complaints included proptosis (n=10; 83%) and swelling in the upper eyelid (n=2; 17%)...
December 8, 2017: Eye
https://www.readbyqxmd.com/read/29215446/nasal-septal-cavernous-hemangioma
#6
Ahmet Baki
Hemangiomas are benign tumors originating from the skin, mucosa, muscle, gland, and vascular tissue in the bone. Although it is common in the head and neck region, it is rarely seen in the nasal cavity and paranasal sinuses. Histologically capillary, cavernous, and mixed types are present, the most common is cavernous-type hemangioma. Cavernous hemangiomas in the nasal cavity, generally originated from the lateral nasal wall, cause symptoms as nasal obstruction and epistaxis. In the author's patient, cavernous hemangioma was originated from the nasal septum, where rarely seen...
December 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29212484/clinical-features-of-visual-disturbances-secondary-to-isolated-sphenoid-sinus-inflammatory-diseases
#7
Lanlan Chen, Libin Jiang, Bentao Yang, Prem S Subramanian
BACKGROUND: Visual disturbances associated with isolated sphenoid sinus inflammatory diseases (ISSIDs) are easily misdiagnosed due to the nonspecific symptoms and undetectable anatomical location. The main objective of this retrospective case series is to investigate the clinical features of visual disturbances secondary to ISSIDs. METHODS: Clinical data of 23 patients with unilateral or bilateral visual disturbances secondary to ISSIDs from 2004 to 2014 with new symptoms were collected...
December 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29211048/imaging-characteristics-of-malignant-sinonasal-tumors
#8
REVIEW
Masaya Kawaguchi, Hiroki Kato, Hiroyuki Tomita, Keisuke Mizuta, Mitsuhiro Aoki, Akira Hara, Masayuki Matsuo
Malignancies of the nasal cavity and paranasal sinuses account for 1% of all malignancies and 3% of malignancies of the upper aerodigestive tract. In the sinonasal tract, nearly half of all malignancies arise in the nasal cavity, whereas most of the remaining malignancies arise in the maxillary or ethmoid sinus. Squamous cell carcinoma is the most common histological subtype of malignant tumors occurring in this area, followed by other epithelial carcinomas, lymphomas, and malignant soft tissue tumors. Although many of these tumors present with nonspecific symptoms, each tumor exhibits characteristic imaging features...
December 6, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29210519/air-pollutants-may-be-environmental-risk-factors-in-chronic-rhinosinusitis-disease-progression
#9
Leila J Mady, Hannah L Schwarzbach, John A Moore, Robert M Boudreau, Thomas J Willson, Stella E Lee
BACKGROUND: Little is known about the role of environmental exposures in the pathophysiology of chronic rhinosinusitis (CRS). In this study, we measured the impact of air pollutants (particulate matter 2.5 [PM2.5 ] and black carbon [BC]) on CRS with nasal polyposis (CRSwNP) and CRS without nasal polyposis (CRSsNP). METHODS: Spatial modeling from pollutant monitoring sites was used to estimate exposures surrounding residences for patients meeting inclusion criteria (total patients, n = 234; CRSsNP, n = 96; CRSwNP, n = 138)...
December 6, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29210513/the-efficacy-of-a-novel-budesonide-chitosan-gel-on-wound-healing-following-endoscopic-sinus-surgery
#10
Thanh Ha, Rowan Valentine, Stephen Moratti, Lyall Hanton, Simon Robinson, Peter-John Wormald
BACKGROUND: Adhesion formation and ostial stenosis are common causes of surgical failure after endoscopic sinus surgery (ESS). Postoperative topical steroid application has been shown to improve wound healing. Chitosan-dextran gel (CD gel) is an effective hemostatic nasal dressing. This study aims to determine the effect of the addition of budesonide to CD gel on postoperative ostial stenosis and adhesion formation following ESS. METHODS: This prospective, blinded, randomized controlled trial was conducted between October 2012 and April 2015...
December 6, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29210505/pulmonary-aspiration-of-sinus-secretions-in-patients-with-cystic-fibrosis
#11
Jacob Nelson, Peter Karempalis, Jordan Dunitz, Ryan Hunter, Holly Boyer
BACKGROUND: Indirect evidence suggests that sinonasal secretions are aspirated into the lungs of patients with cystic fibrosis (CF), contributing to infection, subsequent tissue damage, and decreased lung function. Our objective is to determine whether sinonasal secretions are transferred to the lungs in patients with CF-related sinus disease and healthy subjects, particularly in the recumbent position and during sleep. METHODS: We performed a prospective, controlled trial to detect pulmonary aspiration of radiolabeled albumin applied to the nasal mucosa of study subjects with chronic sinusitis related to CF and control subjects without sinus disease...
December 6, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29209499/nasal-muco-ciliary-transport-time-alteration-efficacy-of-18-b-glycyrrhetinic-acid
#12
Desiderio Passali, Chiara Cappello, Giulio Cesare Passali, Cemal Cingi, Codrut Sarafoleanu, Luisa Maria Bellussi
Background: Mucociliary clearance is the main self-clearing system of the nasal cavity and paranasal sinuses.This is a very important means of non specific defence against continuous organic and inorganic contamination conveyed by air. It works by trapping particles and microorganisms in the mucus and then by transporting the mucous film to the pharynx where it is eliminated with a cough or swallowed. Its congenital or acquired abnormalities are involved in the occurrence of widespread infectious and often severe nose and paranasal sinuses diseases; generally concerning the rhinopharyngealtubal district...
2017: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29205085/incidence-and-survival-of-sinonasal-adenocarcinoma-by-site-and-histologic-subtype
#13
Suat Kılıç, Ruwaa Samarrai, Sarah S Kılıç, Mina Mikhael, Soly Baredes, Jean Anderson Eloy
OBJECTIVE: To determine the incidence and survival of sinonasal adenocarcinoma (SNAC) by subsite and histologic subtype. STUDY DESIGN: Retrospective database review. METHODS: Using the SEER database, we performed a retrospective analysis, identified cases of SNAC diagnosed between 1973 and 2013 and analyzed demographic, histopathology, clinicopathology, and determinants of disease specific survival (DSS). RESULTS: A total of 746 patients with SNAC were identified...
December 5, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29204922/usefulness-of-our-proposed-olfactory-scoring-system-during-endoscopic-sinus-surgery-in-patients-with-chronic-rhinosinusitis
#14
Ken Okazaki, Kenzo Tsuzuki, Kengo Hashimoto, Hiroki Nishikawa, Hironori Takebayashi, Hideki Oka, Yusuke Kojima, Yoriko Yukitatsu, Yasuo Mishiro, Masafumi Sakagami
INTRODUCTION: The primary aim of the current study was to examine the usefulness of our proposed olfactory scoring system in chronic rhinosinusitis (CRS) patients with olfactory disorders (n = 213) receiving endoscopic sinus surgery (ESS). MATERIALS AND METHODS: Analyzed patients were divided into two groups: an eosinophilic CRS (ECRS) group (n = 153); and a non-ECRS group (n = 60). The T&T recognition threshold test was used to evaluate olfaction at baseline and at 3 and 12 months after ESS...
December 4, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29204589/hyoid-myotomy-and-suspension-without-simultaneous-palate-or-tongue-base-surgery%C3%A2-for-obstructive-sleep-apnea
#15
Adrian A Ong, Jonathan Buttram, Shaun A Nguyen, Dustin Platter, Michael R Abidin, M Boyd Gillespie
Objective: Determine the effects of hyoid myotomy and suspension (HMS) without concurrent palatal or tongue base sleep surgery for obstructive sleep apnea (OSA). Method: Patients with OSA treated with HMS were identified using CPT code (21685) at an academic and private sleep surgery clinic. Those who underwent concurrent palatal or tongue base sleep surgery were excluded. Outcomes included simultaneous procedures, apnea-hypopnea index (AHI), lowest oxyhemoglobin saturation (LSAT), and Epworth Sleepiness Scale (ESS)...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204580/etiology-of-sinonasal-inverted-papilloma-a-narrative-review
#16
REVIEW
Ming-Jie Wang, Julia E Noel
Objective: Sinonasal inverted papilloma (IP) is a benign and uncommon tumor of the nasal cavity and paranasal sinuses with a tendency for recurrence and even malignant transformation. Though the morphology and clinical behavior of this lesion has been well described, its etiology remains controversial. Methods: Computerized searches were performed in PubMed, Scopus, and Google scholar through May 2015. In this review, etiologic factors including human papilloma virus (HPV), Epstein-Barr virus (EBV), cell cycle related proteins and angiogenic factors, occupational and environmental exposures, and chronic inflammation, will be discussed...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204576/comparison-of-3%C3%A2-mm-versus-4%C3%A2-mm-rigid-endoscope-in-diagnostic-nasal-endoscopy
#17
Gregory S Neel, Ryan L Kau, Stephen F Bansberg, Devyani Lal
Objective: Compare nasal endoscopy with 3 mm versus conventional 4 mm rigid 30° endoscopes for visualization, patient comfort, and examiner ease. Methods: Ten adults with no previous sinus surgery underwent bilateral nasal endoscopy with both 4 mm and 3 mm endoscopes (resulting in 20 paired nasal endoscopies). Visualization, patient discomfort and examiner's difficulty were assessed with every endoscopy. Sino-nasal structures were checked on a list if visualized satisfactorily...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204573/protective-and-antifungal-properties-of-nanodisk-amphotericin-b-over-commercially-available-amphotericin-b
#18
Do-Yeon Cho, Kyle J Hoffman, Gobind S Gill, Dong-Jin Lim, Daniel Skinner, Calvin Mackey, Steven M Rowe, Bradford A Woodworth
Objective: Amphotericin B (AMB), a potent antifungal agent, has been employed as topical and systemic therapy for sinonasal fungal infections. A novel formulation of nanodisc (ND) containing super aggregated AMB (ND-AMB) for the treatment of fungal infections has been recently developed to provide greater protection from AMB toxicity than current, clinically approved lipid-based formulations. The objective of the current study was to evaluate the safety and potency of ND-AMB for sinonasal delivery using an in vitro model...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29202870/clinical-predictors-of-chronic-rhinosinusitis-do-the-canadian-clinical-practice-guidelines-for-acute-and-chronic-rhinosinusitis-predict-ct-confirmation-of-disease
#19
Paige Moore, Brian Blakley, Eric Meen
BACKGROUND: The diagnosis of chronic rhinosinusitis (CRS) based on clinical presentation alone remains challenging. To improve the accuracy of clinical diagnosis, the Canadian Rhinosinusitis Guidelines recommend the use of specific symptom and endoscopic criteria. Our study objective was to determine whether symptom and endoscopic criteria, as defined by the Canadian Rhinosinusitis Guidelines, accurately predict CT-confirmed CRS diagnosis. METHODS: A retrospective cohort study of 126 patients who underwent CT sinuses based on clinical suspicion of possible CRS...
December 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29202566/post-operative-nebulized-sodium-hyaluronate-versus-spray-after-functional-endoscopic-sinus-surgery-for-chronic-rhinosinusitis
#20
M Casale, A Pace, A Moffa, P Vella, L Sabatino, M A Lopez, F Salvinelli
We prospectively evaluated the efficacy of nebulized Hyaluronic Acid (HA) as an adjuvant treatment to hasten the improvement of nasal respiration and to minimize patients’ discomfort in the postoperative functional endoscopic sinus surgery (FESS) for chronic rhino-sinusitis (CRS). We enrolled 33 CRS adult patients who underwent endoscopic functional sinus surgery. They were randomly assigned into two groups: Spray-Sol group (18 patients) with HA nebulized with a new nasal device named Spray-Sol and Spray group (15 patients) with a HA nebulized with a common spray...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
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