Guodong Wang, Nan Jiang, Hangbo Yu, Xinxin Niu, Mengmeng Huang, Yulong Zhang, Wenying Zhang, Jinze Han, Mengmeng Xu, Runhang Liu, Ziwen Wu, Jingzhe Han, Suyan Wang, Li Gao, Hongyu Cui, Yanping Zhang, Yuntong Chen, Yulong Gao, Xiaole Qi
Infectious bursa disease (IBD) is an acute, highly contactable, lethal, immunosuppressive infectious disease caused by the Infectious bursa disease virus (IBDV). Currently, the emerged novel variant IBDV (nVarIBDV) and the sustainedly prevalent very virulent IBDV (vvIBDV) are the two most prevalent strains of IBDV in China. The antigenic properties of the two prevalent strains differed significantly, which led to the escape of nVarIBDV from the immune protection provided by the existing vvIBDV vaccine. However, the molecular basis of the nVarIBDV immune escape remains unclear...
April 15, 2024: Veterinary Microbiology