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Maria Braoudaki, George I Lambrou, Krinio Giannikou, Vasilis Milionis, Kalliopi Stefanaki, Diane K Birks, Neophytos Prodromou, Aggeliki Kolialexi, Antonis Kattamis, Chara A Spiliopoulou, Fotini Tzortzatou-Stathopoulou, Emmanouel Kanavakis
BACKGROUND: Although, substantial experimental evidence related to diagnosis and treatment of pediatric central nervous system (CNS) neoplasms have been demonstrated, the understanding of the etiology and pathogenesis of the disease remains scarce. Recent microRNA (miRNA)-based research reveals the involvement of miRNAs in various aspects of CNS development and proposes that they might compose key molecules underlying oncogenesis. The current study evaluated miRNA differential expression detected between pediatric embryonal brain tumors and normal controls to characterize candidate biomarkers related to diagnosis, prognosis and therapy...
2014: Journal of Hematology & Oncology
Julián Sanz Esponera
Meningiomas are still defined as benignant tumours although 25% of those tumours will have local recurrance in the follow-up period. The WHO (2000) classification divides meningiomas in three goups: Grade 1 for conventional meningioma. Grade 2 for atypical meningioma and Grade 3 for Anaplastic meningioma. Specific histological variants of meningiomas have been included in grade 2 tumours. Clear cell, rabdoid and papillary meningiomas. We obtained 250 meningiomas from our files and we analyzed 30 inmunohistochemical markers...
2007: Anales de la Real Academia Nacional de Medicina
Yasushi Nishihira, Chun-Feng Tan, Junko Hirato, Junichi Yoshimura, Kenichi Nishiyama, Hideaki Takahashi, Yukihiko Fujii, Hitoshi Takahashi
Two embryonal CNS tumors, atypical teratoid/rabdoid tumor (AT/RT) and primitive neuroectodermal tumor (PNET), may be confused with each other and misdiagnosed. Here we report an infant with a congenital supratentorial tumor, which was detected by fetal MRI at 37 weeks gestation. On routine histological examination, the tumor was composed mainly of small undifferentiated cells, among which many rhabdoid cells and occasional sickle-shaped embracing cells were observed. No mesenchymal or epithelial areas were evident...
December 2007: Neuropathology: Official Journal of the Japanese Society of Neuropathology
G Giraudo, G Del Genio, F Porpiglia, D Parini, C Garrone, M Morino
AIM: Personal experience in laparoscopic adrenalectomies (LA) for secreting and non-secreting tumors is presented. METHODS: Between March 1995 and December 2001 a total of 111 LA (58 left, 49 right and 4 bilateral) were performed in 60 females and 51 males, mean age 47.5 (range 8-81) years, for: 38 Conn diseases, 24 incidentalomas, 15 pheochromocytomas, 13 Cushing diseases, 4 kysts, 3 angiomyolipomas, 1 adreno-genital syndrome, 1 hydatidosis, 1 hyperplasia, 1 ganglioneuroma, 1 oncocyte adenoma, 1 adrenal fibrous tumor, 4 cortical carcinomas and 4 metastases (from renal carcinoma, breast carcinoma, leiomyosarcoma and rabdoid sarcoma, respectively)...
February 2004: Minerva Chirurgica
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