keyword
MENU ▼
Read by QxMD icon Read
search

Endometrial receptivity

keyword
https://www.readbyqxmd.com/read/28723687/small-intestine-submucosa-is-a-potential-material-for-intrauterine-adhesions-treatment-in-a-rat-model
#1
Desheng Kong, Lin Zhang, Xin Xu, Jingkun Zhang, Yanan Li, Xianghua Huang
OBJECTIVE: To study whether small intestine submucosa (SIS) could be a treatment option for preventing the formation of intrauterine adhesions (IUAs). METHODS: The IUAs model was established by mechanical curettage and infectious injury in a rat model. One uterine horn of the rat model was treated with the transplantation of SIS (SIS group) and the other one was left without any treatment (control group). The endometrium was evaluated with endometrial thickness, number of glands and fibrosis area...
July 20, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28706275/novel-function-of-pregnancy-associated-plasma-protein-a-promotes-endometrium-receptivity-by-up-regulating-n-fucosylation
#2
Ming Yu, Jiao Wang, Shuai Liu, Xiaoqi Wang, Qiu Yan
Glycosylation of uterine endometrial cells plays important roles to determine their receptive function to blastocysts. Trophoblast-derived pregnancy-associated plasma protein A (PAPPA) is specifically elevated in pregnant women serum, and is known to promote trophoblast cell proliferation and adhesion. However, the relationship between PAPPA and endometrium receptivity, as well as the regulation of N-fucosylation remains unclear. We found that rhPAPPA and PAPPA in the serum samples from pregnant women or conditioned medium of trophoblast cells promoted endometrium receptivity in vitro...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28702979/use-of-platelet-rich-plasma-in-human-infertility
#3
G V L Colombo, V Fanton, D Sosa, E Criado Scholz, J Lotti, S E Aragona, T Lotti
Successful embryo implantation requires good quality embryo but also needs a receptive endometrium site. In our clinical practice, we daily verify that an adequate endometrial growth is reached for successful implantation. To understand whether platelet rich plasma (PRP) can improve endometrium thickness and performance, PRP treatment was carried out after at least three of the classic medical protocols currently in use had been unsuccessfully adopted. Eight patients with more than 3 cryo-transfers cancelled because of failure of endometrial growth, defined as endometrium less than 6 mm, with negative hysteroscopic screening for endometrial pathology, and with negative bacteriologic screening, before present and all previous treatment, were selected to undergo PRP treatment...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28683601/dysregulation-of-gda-expression-in-endometrium-of-women-with-endometriosis-implication-for-endometrial-receptivity
#4
Riccardo Focarelli, Alice Luddi, Vincenzo De Leo, Angela Capaldo, Anita Stendardi, Valentina Pavone, Linda Benincasa, Giuseppe Belmonte, Felice Petraglia, Paola Piomboni
Glycodelin-A (GdA) has been proposed to represent a potential biomarker of endometrial function, but little is known about its expression during the different phases of the menstrual cycle and under pathological conditions. In the light of its potential importance also in embryo implantation, we aimed to evaluate the expression profile of GdA as well as the presence of different glycosylated glycoforms and the immunolocalization in endometrial tissue from women with endometriosis and in women with proven fertility, at different times during the menstrual cycle...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28678802/mir-182-aids-in-receptive-endometrium-development-in-dairy-goats-by-down-regulating-ptn-expression
#5
Lei Zhang, Xiaorui Liu, Junze Liu, Zhanqin Zhou, Yuxuan Song, Binyun Cao, Xiaopeng An
Increasing evidence has shown that miRNAs play important roles in endometrium development during the menstrual cycle in humans and many other animals. Our previous data indicated that miR-182 levels increase 15.55-fold and pleiotrophin (PTN) levels decrease 20.97-fold in the receptive endometrium (RE, D15) compared with the pre-receptive endometrium (PE, D5) in dairy goats. The present study shows that miR-182 is widely expressed in different tissues of dairy goats and that its expression levels are regulated by E2 and P4 in endometrial epithelium cells (EECs)...
2017: PloS One
https://www.readbyqxmd.com/read/28676452/water-extracted-tubers-of-cyperus-rotundus-l-enhance-endometrial-receptivity-through-leukemia-inhibitory-factor-mediated-expression-of-integrin-%C3%AE-v%C3%AE-3-and-%C3%AE-v%C3%AE-5
#6
Hee-Jung Choi, Tae-Wook Chung, Mi-Ju Park, Yeon-Seop Jung, Syng-Ook Lee, Keuk-Jun Kim, Ki-Tae Ha
ETHNOPHARMACOLOGICAL RELEVANCE: Cyperus rotundus L. (CR) has been traditionally used as an herbal medicine in Asian countries to treat diverse gynecological disorders. However, the potential therapeutic effect of CR on endometrial receptivity for successful embryo implantation to treat female infertility has not been fully studied. AIM OF STUDY: The aim of this study was to evaluate the effect of water-extracted CR on endometrial receptivity by investigating the expression of leukemia inhibitory factor (LIF) and integrins, cell adhesion, and embryo implantation using mifepristone (RU486; RU)-induced implantation failure model...
July 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28668152/endometrial-receptivity-in-eutopic-endometrium-in-patients-with-endometriosis-it-is-not-affected-and%C3%A2-let-me-show-you-why
#7
REVIEW
Jose Miravet-Valenciano, María Ruiz-Alonso, Eva Gómez, Juan A Garcia-Velasco
Many women with endometriosis experience compromised fertility. This disease clearly exerts quantitative damage on the ovaries, and perhaps, also qualitative damage. However, it remains controversial whether endometrial receptivity is compromised. Here we review the evidence from basic transcriptomic signature data to clinical data from an oocyte donation model and find support for the concept that endometrial receptivity is not impaired in women with endometriosis when healthy embryos reach the endometrial cavity...
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28668151/implantation-failure-of-endometrial-origin-it-is-not-pathology-but-our-failure-to-synchronize-the-developing-embryo-with-a-receptive-endometrium
#8
REVIEW
Cecilia T Valdes, Amy Schutt, Carlos Simon
Repeated implantation failure (RIF) is an intriguing, massive failure of reproductive treatment in otherwise healthy women leading to the introduction of empirical adjuvant interventions that are costly, inefficient, and frustrating for our patients. In this article, we will try to convince the readers that RIF is neither a stigma nor a mysterious pathology but rather our failure to diagnose and properly synchronize the euploid blastocyst with the patient's personalized window of implantation.
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28634372/dna-methylation-changes-in-endometrium-and-correlation-with-gene-expression-during-the-transition-from-pre-receptive-to-receptive-phase
#9
Viktorija Kukushkina, Vijayachitra Modhukur, Marina Suhorutšenko, Maire Peters, Reedik Mägi, Nilufer Rahmioglu, Agne Velthut-Meikas, Signe Altmäe, Francisco J Esteban, Jaak Vilo, Krina Zondervan, Andres Salumets, Triin Laisk-Podar
The inner uterine lining (endometrium) is a unique tissue going through remarkable changes each menstrual cycle. Endometrium has its characteristic DNA methylation profile, although not much is known about the endometrial methylome changes throughout the menstrual cycle. The impact of methylome changes on gene expression and thereby on the function of the tissue, including establishing receptivity to implanting embryo, is also unclear. Therefore, this study used genome-wide technologies to characterize the methylome and the correlation between DNA methylation and gene expression in endometrial biopsies collected from 17 healthy fertile-aged women from pre-receptive and receptive phase within one menstrual cycle...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28631552/effect-of-2-3-4-4-5-pentachlorobiphenyl-exposure-on-endometrial-receptivity-and-the-methylation-of-hoxa10
#10
Xin-Lan Qu, Ming-Zhang, Yuan-Fang, Hui Wang, Yuan-Zhen Zhang
Polychlorinated biphenyls (PCBs) are one of the most common endocrine-disrupting chemicals and have obvious toxicity on human reproductive development. The aim of our study was to investigate the toxicity of chronic 2,3',4,4',5-pentachlorobiphenyl (PCB 118) exposure on embryo implantation and endometrial receptivity, with the possible mechanism of DNA methylation involved. Virgin CD-1 female mice (3 weeks old) were housed and orally treated with PCB 118 (0, 1, 10, 100 μg/kg) for a month. After mating with fertile males, the pregnant mice were killed on gestation day 4...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28630707/evidence-of-endometrial-amino-acid-metabolism-and-transport-modulation-by-peri-ovulatory-endocrine-profiles-driving-uterine-receptivity
#11
Moana Rodrigues França, Maressa Izabel Santos da Silva, Guilherme Pugliesi, Veerle Van Hoeck, Mario Binelli
BACKGROUND: In beef cattle, changes in the periovulatory endocrine milieu are associated with fertility and conceptus growth. A large preovulatory follicle (POF) and the resulting elevated concentrations of progesterone (P4) during diestrus positively affect pregnancy rates. Amino acids (AA) are important components of maternally derived secretions that are crucial for embryonic survival before implantation. The hypothesis is that the size of the POF and the concentration of P4 in early diestrus modulate the endometrial abundance of SLC transcripts related to AA transport and metabolism and subsequently impact luminal concentrations of AA...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28629172/the-role-of-hcg-in-implantation-a-mini-review-of-molecular-and-clinical-evidence
#12
REVIEW
Antonis Makrigiannakis, Thomas Vrekoussis, Emmanouel Zoumakis, Sophia N Kalantaridou, Udo Jeschke
Embryo implantation is a complex process involving continuous molecular cross-talk between the embryo and the decidua. One of the key molecules during this process is human chorionic gonadotropin (HCG). HCG effectively modulates several metabolic pathways within the decidua contributing to endometrial receptivity. Herein, a brief overview of the molecular mechanisms regulated by HCG is presented. Furthermore, we summarize the existing evidence regarding the clinical impact on reproductive outcomes after endometrial priming with HCG prior to embryo transfer...
June 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28628266/embryo-maternal-dialogue-during-pregnancy-establishment-and-implantation-in-the-pig
#13
REVIEW
Agnieszka Waclawik, Monika M Kaczmarek, Agnieszka Blitek, Piotr Kaczynski, Adam J Ziecik
Porcine conceptuses secrete pregnancy-recognition signals (estrogens, including estradiol-17β) that inhibit luteolysis, thereby prolonging progesterone production by corpora lutea. The supportive mechanism by which the conceptus also inhibits luteolysis is by shifting endometrial prostaglandin (PG) synthesis to luteoprotective PGE2. Progesterone stimulates endometrial production of factors that are essential for conceptus development. Priming the uterus by progesterone and loss of progesterone receptors from the uterine epithelium by D1ay 10-12 after estrus are key for achieving endometrial receptivity for implantation...
June 19, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28602477/endometrial-receptivity-in-the-eutopic-endometrium-of-women-with-endometriosis-it-is-affected-and-let-me-show-you-why
#14
REVIEW
Bruce A Lessey, J Julie Kim
The endometrium maintains complex controls on proliferation and apoptosis as part of repetitive menstrual cycles that prepare the endometrium for the window of implantation and pregnancy. The reliance on inflammatory mechanisms for both implantation and menstruation creates the opportunity in the setting of endometriosis for establishment of chronic inflammation that is disruptive to endometrial receptivity, causing both infertility and abnormal bleeding. Clinically, there can be little doubt that the endometrium of women with endometriosis is less receptive to embryo implantation, and strong evidence exists to suggest that endometrial changes are associated with decreased cycle fecundity as a result of this disease...
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28600051/histological-component-quantification-for-the-evaluation-of-endometrial-receptivity-in-women-with-natural-cycles-undergoing-in%C3%A2-vitro-fertilization-intracytoplasmic-sperm-injection
#15
Dong-Ying Wang, Li Tian, Danhua Shen, Zhen-Juan Yang
OBJECTIVE: Our aim was to evaluate the value of the volumetric fraction of vascular endothelial cells (EnVF) for determining endometrial receptivity in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIALS AND METHODS: The records of women undergoing IVF/ICSI between 2006 and 2010 were retrospectively reviewed. An endometrial biopsy was performed in the cycle prior to IVF/ICSI. EnVF was calculated from endometrial biopsy staining...
June 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28577574/activating-transcription-factor-3-promotes-embryo-attachment-via-up-regulation-of-leukemia-inhibitory-factor-in-vitro
#16
Xi Cheng, Jingyu Liu, Huizhi Shan, Lihua Sun, Chenyang Huang, Qiang Yan, Ruiwei Jiang, Lijun Ding, Yue Jiang, Jianjun Zhou, Guijun Yan, Haixiang Sun
BACKGROUND: A receptive endometrium is essential for maternal-embryonic molecular communication during implantation. However, the specific molecular regulatory mechanisms of the endometrial capacity remain poorly understood. Here, we examined activating transcription factor 3 (ATF3) expression in human endometria and the functional effect of ATF3 on embryo attachment in vitro. METHODS: Immunohistochemistry (IHC) was used to assess the ATF3 expression patterns in human endometria...
June 2, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28574291/temperature-sensitive-heparin-modified-poloxamer-hydrogel-with-affinity-to-kgf-facilitate-the-morphologic-and-functional-recovery-of-the-injured-rat-uterus
#17
He-Lin Xu, Jie Xu, Si-Si Zhang, Qun-Yan Zhu, Bing-Hui Jin, De-Li ZhuGe, Bi-Xin Shen, Xue-Qing Wu, Jian Xiao, Ying-Zheng Zhao
Endometrial injury usually results in intrauterine adhesion (IUA), which is an important cause of infertility and recurrent miscarriage in reproductive women. There is still lack of an effective therapeutic strategy to prevent occurrence of IUA. Keratinocyte growth factor (KGF) is a potent repair factor for epithelial tissues. Here, a temperature-sensitive heparin-modified poloxamer (HP) hydrogel with affinity to KGF (KGF-HP) was used as a support matrix to prevent IUA and deliver KGF. The rheology of KGF-HP hydrogel was carefully characterized...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28571815/hypothesis-co-transfer-of-genuine-embryos-and-implantation-promoting-compounds-via-artificial-containers-improve-endometrium-receptivity
#18
Onder Celik, Mustafa Acet, Sudenaz Celik, Levent Sahin, Onder Koc, Nilufer Celik
As with other organs endometrial functions are altered with the advancing age. Age related decrease in reproductive functions leads to decline in the number of oocytes retrieved and the synthesis of endometrial receptivity molecules. Despite the significant improvement in assisted reproductive technologies we do not have so many options to enhance endometrial receptivity. Due to lack of drugs having endometrium receptivity enhancement properties, oocyte donation seems to be the only solution for women with implantation failure...
June 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28562440/vitamin-d-in-human-reproduction
#19
Jason M Franasiak, Evelin E Lara, Antonio Pellicer
PURPOSE OF REVIEW: Vitamin D deficiency has been associated with a wide range of human disease states and the global epidemic, particularly in reproductive aged women, has led to a focus on this complex hormones role in human reproduction. Indeed vitamin D receptors are found throughout the reproductive tract in the ovary, endometrium, and the placenta. It has roles both in calcium-dependent and independent pathways. However, agreement upon the most appropriate way to assess vitamin D status and ultimately its activity at various sites has proven challenging...
August 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28559342/follistatin-is-critical-for-mouse-uterine-receptivity-and-decidualization
#20
Paul T Fullerton, Diana Monsivais, Ramakrishna Kommagani, Martin M Matzuk
Embryo implantation remains a significant challenge for assisted reproductive technology, with implantation failure occurring in ∼50% of in vitro fertilization attempts. Understanding the molecular mechanisms underlying uterine receptivity will enable the development of new interventions and biomarkers. TGFβ family signaling in the uterus is critical for establishing and maintaining pregnancy. Follistatin (FST) regulates TGFβ family signaling by selectively binding TGFβ family ligands and sequestering them...
June 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
keyword
keyword
19021
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"