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https://www.readbyqxmd.com/read/28528582/searching-the-web-a-survey-on-the-quality-of-advice-on-postnatal-sequelae-of-intrauterine-growth-restriction-and-the-implication-of-developmental-origins-of-health-and-disease
#1
S Perzel, H Huebner, W Rascher, C Menendez-Castro, A Hartner, F B Fahlbusch
Intrauterine growth restriction (IUGR) and fetal growth restriction (FGR) are pregnancy complications associated with morbidity in later life. Despite a growing body of evidence from current research on developmental origins of health and disease (DOHaD), little information is currently provided to parents on long-term metabolic, cardiovascular and neurologic consequences. As parents strongly rely on internet-based health-related information, we examined the quality of information on IUGR/FGR sequelae and DOHaD in webpages used by laypersons...
May 22, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28526519/oxytocin-administration-during-spontaneous-labor-guidelines-for-clinical-practice-chapter-4-oxytocin-efficiency-according-to-implementation-in-insufficient-spontaneous-labor
#2
Bénédicte Coulm, Véronique Tessier
AIM: To describe the optimal procedures for administering oxytocin in cases of insufficient uterine contractility during spontaneous labor and the maternal and fetal monitoring to accompany it. METHODS: Systematic review of the literature by consultation of the Medline, Micromedex, and Cochrane databases, and international guidelines. RESULTS: Oxytocin must be administered only in hospital settings and monitored according to a written departmental protocol...
May 16, 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28526449/predictors-of-vaginal-delivery-in-medically-indicated-early-preterm-induction-of-labor
#3
Rachel A Sievert, Spencer G Kuper, Victoria C Jauk, Melissa Parrish, Joseph R Biggio, Lorie M Harper
BACKGROUND: When delivery is indicated prior to 34 weeks, many providers perform a cesarean delivery (CD) rather than induce labor based on perceptions of a high failure rate. Given the morbidity of CD, an accurate estimate of the success rate and factors associated with success in preterm induction of labor (IOL) is important in management decisions. OBJECTIVE: We sought to develop a prediction model for successful induction of labor in preterm patients using factors known at the time the decision is made to deliver...
May 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28523332/apert-syndrome-clinical-case
#4
Mirela Anişoara Siminel, Cristian Ovidiu NeamŢu, Damian DiŢescu, Mircea Cătălin ForŢofoiu, Alexandru Cristian Comănescu, Marius Bogdan Novac, Simona Daniela NeamŢu, Adrian Gluhovschi
Apert syndrome - acrocephalosyndactyly - is a rare autosomal dominant disorder representing 1:65 000 cases of living newborns. Characteristic malformations of the Apert syndrome are early craniostenosis, microviscerocranium and II-V finger syndactyly of hand and toes with proximal phalanx of the bilateral thumb "in delta". It is difficult to determine prenatal diagnosis in the second quarter, when examining the morphology of fetal signs; the dysmorphism signs appeared in the third pregnancy quarter. We present here the case of a newborn with Apert syndrome that was born prematurely in our Clinic after a monitored pregnancy, where there was issued a suspicion of cranio-facial dysmorphism, malposition and malformation of the feet and hands in the third quarter of prenatal pregnancy...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28519244/neonatal-abstinence-syndrome-update-on-diagnostic-and-therapeutic-strategies
#5
Genny Raffaeli, Giacomo Cavallaro, K Karel Allegaert, Enno Diederik Wildschut, Monica Fumagalli, Massimo Agosti, Dick Tibboel, Fabio Mosca
Substance use among pregnant women is a major public health issue. Both prescription opioid use and illicit opioid abuse have increased dramatically in recent years. Prolonged in utero drug exposure may result in neonatal abstinence syndrome (NAS), an acute multisystemic clinical entity that occurs in the first days of life. This syndrome is caused by abrupt discontinuation of fetal exposure to licit or illicit drugs chronically consumed by the mother during pregnancy and transmitted to the fetus through the placenta...
May 18, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28509860/a-combined-independent-source-separation-and-quality-index-optimization-method-for-fetal-ecg-extraction-from-abdominal-maternal-leads
#6
Lucia Billeci, Maurizio Varanini
The non-invasive fetal electrocardiogram (fECG) technique has recently received considerable interest in monitoring fetal health. The aim of our paper is to propose a novel fECG algorithm based on the combination of the criteria of independent source separation and of a quality index optimization (ICAQIO-based). The algorithm was compared with two methods applying the two different criteria independently-the ICA-based and the QIO-based methods-which were previously developed by our group. All three methods were tested on the recently implemented Fetal ECG Synthetic Database (FECGSYNDB)...
May 16, 2017: Sensors
https://www.readbyqxmd.com/read/28509326/polish-gynecological-society-recommendations-for-labor-induction
#7
Dorota Bomba-Opoń, Krzysztof Drews, Hubert Huras, Piotr Laudański, Tomasz Paszkowski, Mirosław Wielgoś
Labor induction involves artificial stimulation of childbirth before the natural, spontaneous onset of labor. It is one of the most common procedures in modern obstetrics. The frequency of labor induction has doubled in recent decades due to the development of perinatology and methods of monitoring fetal well-being in particular. Currently, one in five pregnant women and 30-40% of women delivering vaginally undergo this procedure. Reasons for induction include reduction of the perinatal mortality and morbidity of the fetus and newborn, as well as the reduction of maternal complications...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28507627/prenatally-diagnosis-and-outcome-of-fetuses-with-cardiac-rhabdomyoma-single-centre-experience
#8
Ramush Bejiqi, Ragip Retkoceri, Hana Bejiqi
BACKGROUND: Cardiac rhabdomyoma (CRs) are the most common primary tumour of the heart in infants and children. Usually are multiple and, basing on the location can cause a haemodynamic disturbance, dysrhythmias or heart failure during the fetal and early postnatal period. CRs have a natural history of spontaneous regression and are closely associated with tuberous sclerosis complex (TSC). It has an association with tuberous sclerosis (TS), and in those, the tumour may regress and disappear completely, or remain consistent in size...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28500947/electrochemical-latent-redox-ratiometric-probes-for-real-time-tracking-and-quantification-of-endogenous-hydrogen-sulfide-production-in-living-cells
#9
Kesavan Manibalan, Veerappan Mani, Pu-Chieh Chang, Chih-Hung Huang, Sheng-Tung Huang, Kasper Marchlewicz, Suresh Neethirajan
Hydrogen sulfide (H2S) was discovered as a third gasotransmitter in biological systems and recent years have seen a growing interest to understand its physiological and pathological functions. However, one major limiting factor is the lack of robust sensors to quantitatively track its production in real-time. We described a facile electrochemical assay based on latent redox probe approach for highly specific and sensitive quantification in living cells. Two chemical probes, Azido Benzyl ferrocene carbamate (ABFC) and N-alkyl Azido Benzyl ferrocene carbamate (NABFC) composed of azide trigger group were designed...
May 4, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28500781/pregnancy-outcomes-in-simultaneous-pancreas-and-kidney-transplant-recipients-a-national-french-survey-study
#10
G Normand, F Brunner, L Badet, F Buron, M Catton, J Massardier, L Esposito, P Grimbert, G Mourad, J E Serre, S Caillard, G Karam, D Cantarovich, E Morelon, O Thaunat
Simultaneous pancreas and kidney transplantation (SPK) is currently the best therapeutic option for patients with type-1 diabetes and terminal renal failure. Renal transplantation restores fertility enabling women to pursue pregnancies. However, scarcity of available data on pregnancy outcomes in SPK impedes fair medical counseling. Medical files of all pregnancies that lasted ≥3 months among recipients of functional SPK performed between 1990 and 2015 in France were retrospectively analyzed. Twenty-six pregnancies in 22 SPK recipients were identified...
May 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28479738/prenatal-developmental-toxicity-study-of-glycosides-based-standardized-fenugreek-seed-extract-in-rats
#11
Pallavi O Deshpande, Vishwaraman Mohan, Mukul P Pore, Shailesh Gumaste, Prasad A Thakurdesai
CONTEXT: Glycoside-based standardized fenugreek seed extract (SFSE-G) demonstrated promising efficacy in animal models of immune-inflammatory conditions. AIM: The present study was aimed at embryo-fetal development toxicity evaluation of SFSE-G in Wistar rats as per guideline No. 414 of the Organization for Economic Co-operation and Development (OECD). MATERIAL AND METHODS: Mated female rats were randomized into four groups of 30 each and received oral doses of either SFSE-G at 250, 500, and 1000 mg/kg or vehicle (water) during the period of gestation (postconception) from gestational day 5 (GD5, an implantation day) until 1 day before cesarean sections (GD19)...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28476693/oxytocin-administration-during-spontaneous-labor-guidelines-for-clinical-practice-chapter%C3%A2-6-fetal-neonatal-and-pediatric-risks-and-adverse-effects-of-using-oxytocin-augmentation-during-spontaneous-labor
#12
https://www.readbyqxmd.com/read/28475393/fetal-scalp-stimulation-fss-versus-fetal-blood-sampling-fbs-for-women-with-abnormal-fetal-heart-rate-monitoring-in-labor-a-prospective-cohort-study
#13
U Tahir Mahmood, C O'Gorman, Z Marchocki, Y M O'Brien, D J Murphy
OBJECTIVE: To evaluate the performance of fetal scalp stimulation (FSS) compared to fetal blood sampling (FBS) as a second line test of fetal wellbeing in labor. STUDY DESIGN: A prospective cohort study was conducted including 298 fetal blood sampling procedures performed due to abnormal fetal cardiotocography (CTG). Two independent observers interpreted the CTG following stimulation. The FSS test was classified as normal when an elicited acceleration and/or provoked fetal heart rate variability was recorded...
May 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28473291/oxytocin-administration-during-spontaneous-labor-guidelines-for-clinical-practice-chapter-5-maternal-risk-and-adverse-effects-of-using-oxytocin-augmentation-during-spontaneous-labor
#14
https://www.readbyqxmd.com/read/28473289/oxytocin-administration-during-spontaneous-labor-guidelines-for-clinical-practice-chapter-2-indications-of-oxytocin-according-the-first-and-second-stages-of-spontaneous-labor
#15
https://www.readbyqxmd.com/read/28471442/an-antenatal-marker-of-neurodevelopmental-outcomes-in-infants-with-congenital-heart-disease
#16
S Siddiqui, W P Fifer, M Ordonez-Retamar, J D Nugent, I A Williams
OBJECTIVE: Prenatal exposures are known to alter fetal neurodevelopment and autonomic control. We aimed to explore the correlation between fetal autonomic activity, measured by fetal heart rate variability, and 18-month developmental outcome in subjects with congenital heart disease. STUDY DESIGN: From 2010 to 2013, 5 fetuses with hypoplastic left heart syndrome, 9 with transposition of the great arteries and 9 with tetralogy of Fallot were included in this prospective cohort study...
May 4, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28469521/congenital-hepatic-cyst
#17
Aldo Recinos, Tarik Zahouani, Juan Guillen, Benamanahalli Rajegowda
Congenital hepatic cyst is a rare and nonsymptomatic condition in infants and children. Its incidence is 2.5% in the postnatal life with a much lower incidence in the prenatal period. Incidental finding on antenatal imaging is the most common presentation. We present a case of a newborn in whom fetal ultrasound detected a cyst within the fetal liver. Postnatal imaging revealed a liver cyst in the right lobe of the liver, with no other intrahepatic structure affected. Liver function tests were abnormal, but the patient was asymptomatic...
2017: Clinical Medicine Insights. Pediatrics
https://www.readbyqxmd.com/read/28457788/radiological-protection-for-pregnant-women-at-a-large-academic-medical-cancer-center
#18
Bae Chu, Daniel Miodownik, Matthew J Williamson, Yiming Gao, Jean St Germain, Lawrence T Dauer
PURPOSE: Most radiation protection programs, regulations and guidance apply specific restrictions to the occupational exposure of pregnant workers. The aim of this study was to compile data from the declared pregnant woman (DPW) radiation protection program over more than 5years at a large, high-volume, comprehensive oncology academic/medical institution and to evaluate for effectiveness against existing regulations and guidance. METHODS: A retrospective review was performed of the data collected as part of the DPW radiation protection program from January 2010 through May 2016, including the number of declared pregnancies, worker category, personal and fetal dosimetry monitoring measurements, workplace modifications, as well as the monthly and total recorded badge results during the entire pregnancy...
April 27, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28453441/fetal-cardiac-time-intervals-in-healthy-pregnancies-an-observational-study-by-fetal-ecg-monica-healthcare-system
#19
Annette Wacker-Gussmann, Cordula Plankl, Maria Sewald, Karl-Theo Maria Schneider, Renate Oberhoffer, Silvia M Lobmaier
BACKGROUND: Fetal electrocardiogram (fECG) can detect QRS signals in fetuses from as early as 17 weeks' gestation; however, the technique is limited by the minute size of the fetal signal relative to noise ratio. The aim of this study was to evaluate precise fetal cardiac time intervals (fCTIs) with the help of a newly developed fetal ECG device (Monica Healthcare System). METHODS: In a prospective manner we included 15-18 healthy fetuses per gestational week from 32 weeks onwards...
April 28, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28450276/pregnancy-and-bile-acid-disorders
#20
Vanessa Pataia, Peter H Dixon, Catherine Williamson
During pregnancy, extensive adaptations in maternal metabolic and immunological physiology occur. Consequently, pre-existing disease may be exacerbated or attenuated and new disease susceptibility may be unmasked. Cholestatic diseases, characterized by a supraphysiological raise in bile acid levels, require careful monitoring during pregnancy. This review describes the latest advances in the knowledge of intrahepatic cholestasis of pregnancy (ICP), the commonest bile acid disorder specific to pregnancy, with a focus on the disease etiology and potential mechanisms of ICP-associated adverse pregnancy outcomes, including fetal demise...
April 27, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
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