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https://www.readbyqxmd.com/read/29332315/comparison-of-treatment-strategies-for-femoro-popliteal-disease-a-network-meta-analysis
#1
Edward Koifman, Michael J Lipinski, Kyle Buchanan, Won Yu Kang, Ricardo O Escarcega, Ron Waksman, Nelson L Bernardo
OBJECTIVES: We sought to compare treatment strategies in a Bayesian network meta-analysis of randomized controlled trials. BACKGROUND: Peripheral artery disease (PAD) is a prevalent morbidity that is treated with various strategies. METHODS: We performed a MEDLINE search for randomized studies comparing at least 2 treatment strategies, including bypass surgery, percutaneous transluminal angioplasty (PTA) balloons, stents, covered stents, drug-eluting stents (DES), and drug-coated balloons (DCB), in patients with native femoro-popliteal disease...
January 14, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29327573/treating-complex-femoro-popliteal-lesions
#2
Rozemarijn J van der Vijver-Coppen, Yannick W 't Mannetje, Theo P Menting, Jan-Willem Lardenoije, Michel M Reijnen
Peripheral artery disease affects 202 million patients worldwide and may cause disabling intermittent claudication and critical limb ischemia. Next to life style changes, best medical treatment and supervised exercise therapy, it can be necessary to re-vascularise the limb. Treatment of femoro-popliteal lesions poses a challenge and a surgical bypass remains recommended in the guidelines for longer and more complex lesions. Bypass surgery is associated with substantial morbidity and even mortality. Endovascular alternatives are quickly evolving from plain balloon angioplasty to drug-eluting stents, drug-coated balloons, polytetrafluoroethylene covered stents and atherectomy...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29327570/the-detour-procedure-no-more-need-for-conventional-bypass-surgery
#3
Dainis Krievins, Janis Savlovskis, Natalija Ezite, Andrew Hill, Kaspars Kisis, Marcis Gedins, Edgars Zellans, Andrew Holden
BACKGROUND: Long segment occlusive disease in the superficial femoral artery remains a treatment challenge despite advances in open surgical and endovascular approaches. We report initial clinical results of an entirely new procedure to perform femoropopliteal bypass using the DETOUR System to create a stentgraft bypass which originates in the SFA, travels through the femoral vein, and ends in the popliteal artery, bypassing the diseased segment. METHODS: Review the initial results of the first five patients at a single site enrolled in IRB-approved, prospective clinical study using the DETOUR System...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29327474/long-term-effects-of-intralymphatic-immunotherapy-ilit-on-canine-atopic-dermatitis
#4
Katrin Timm, Ralf S Mueller, Claudia S Nett-Mettler
BACKGROUND: Subcutaneous allergen immunotherapy (SCIT) is an established and efficacious therapy for canine atopic dermatitis (AD). In humans, intralymphatic immunotherapy (ILIT) was reported to be associated with fewer and less severe adverse effects than subcutaneous allergen immunotherapy and to be efficacious for several years after three intralymphatic injections. OBJECTIVE: To evaluate safety and effects of ILIT in a case series of dogs with (AD). ANIMALS: Fifty one privately owned dogs with AD...
January 12, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29326153/treatment-effect-of-drug-coated-balloons-is-durable-to-3-years-in-the-femoropopliteal-arteries-long-term-results-of-the-in-pact-sfa-randomized-trial
#5
Peter A Schneider, John R Laird, Gunnar Tepe, Marianne Brodmann, Thomas Zeller, Dierk Scheinert, Christopher Metzger, Antonio Micari, Ravish Sachar, Michael R Jaff, Hong Wang, Melissa S Hasenbank, Prakash Krishnan
BACKGROUND: Randomized controlled trials have reported favorable 1-year outcomes with drug-coated balloons (DCBs) for the treatment of symptomatic peripheral arterial disease when compared with standard percutaneous transluminal angioplasty (PTA). Evidence remains limited on the durability of the treatment effect with DCBs in the longer term. METHODS AND RESULTS: IN.PACT SFA is a single-blind, randomized trial (Randomized Trial of IN.PACT Admiral Paclitaxel-Coated Percutaneous Transluminal Angioplasty [PTA] Balloon Catheter vs Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery [SFA] and/or Proximal Popliteal Artery [PPA]) that enrolled 331 patients with symptomatic (Rutherford 2-4) femoropopliteal lesions up to 18 cm in length...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29317991/successful-recanalization-of-long-femoro-crural-occlusive-disease-after-failed-bypass-surgery
#6
Grigorios Korosoglou, Tom Eisele, Dorothea Raupp, Christoph Eisenbach, Sorin Giusca
Patients with critical limb ischemia necessitate immediate intervention to restore blood flow to the affected limb. Endovascular procedures are currently preferred for these patients. We describe the case of an 80-year-old female patient who presented to our department with ischemic rest pain and ulceration of the left limb. The patient had history of left femoral popliteal bypass surgery, femoral thromboendarterectomy and patch angioplasty of the same limb 2 years ago. Doppler sonography and magnetic resonance angiography revealed an occlusion of the left superficial femoral artery (SFA) and popliteal artery and of all three infra-popliteal arteries...
December 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29317263/keratinocyte-specific-ablation-of-ripk4-allows-epidermal-cornification-but-impairs-skin-barrier-formation
#7
Corinne Urwyler-Rösselet, Giel Tanghe, Kirsten Leurs, Barbara Gilbert, Riet De Rycke, Michiel De Bruyne, Saskia Lippens, Sonja Bartunkova, Philippe De Groote, Carine Niessen, Marek Haftek, Peter Vandenabeele, Wim Declercq
In humans, RIPK4 mutations can lead to the autosomal recessive Bartsocas-Papas and popliteal pterygium syndromes, which are characterized by severe skin defects, pterygia as well as clefting. We show here that the epithelial fusions observed in RIPK4 full KO mice are E-cadherin dependent, as keratinocyte-specific deletion of E-cadherin in RIPK4 full KO mice rescued the tail-to-body fusion and fusion of oral epithelia. To elucidate RIPK4 function in epidermal differentiation and development we generated epidermis-specific RIPK4 knockout mice (RIPK4EKO)...
January 6, 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29311538/popliteal-artery-entrapment-syndrome-a-case-report-and-review-of-the-literature
#8
Francisco Cialdine Frota Carneiro Júnior, Eduardo Nazareno Dos Anjos Carrijo, Samuel Tomaz Araújo, Luis Carlos Uta Nakano, Jorge Eduardo de Amorim, Daniel Guimarães Cacione
BACKGROUND Popliteal artery entrapment syndrome (PAES) results from an anomalous relationship between the popliteal artery and the myofascial structures of the popliteal fossa. The most common presenting symptoms include intermittent pain in the feet and calves on exercise, resulting in lameness. PAES can lead to popliteal artery thrombosis, stenosis, distal arterial thromboembolism, or arterial aneurysm. The treatment of PAES includes surgical exploration with fasciotomy, myotomy, or sectioning of fibrous band formation, to release the popliteal artery...
January 9, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29306852/trichosporon-asahii-septic-thrombophlebitis-following-lower-extremity-amputation-in-an-immunocompetent-host
#9
Pradeep Kumar Mada, Folusakin Ayoade, Ailing Li, John Todd
A 59-year-old man with a history of peripheral vascular disease status post femoral popliteal bypass presented with critical limb ischaemia of the left leg. An arterial Doppler ultrasound showed an occluded graft requiring an above knee amputation. Five days after surgery, the patient developed fever, leucocytosis, significant stump swelling and pain, and serosanguinous discharge from his wound. Wound swab cultures from the stump grew Trichosporon asahii A venous Doppler ultrasound revealed extensive thrombosis of the left lower extremity...
January 6, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29291298/neurofibroma-of-the-peroneal-nerve
#10
Clayton Haldeman, Amgad Hanna
Neurofibromas are benign tumors composed of different cell types from the peripheral nervous system. Neurofibromas infiltrate between nerve fascicles and do not have a discrete capsule. On MRI, they are T1 hypointense or isointense, T2 hyperintense, often with a "target sign," and contrast enhancing. The video shows gross-total resection of a peroneal nerve neurofibroma presenting as a painful mass in the popliteal fossa. Incisions across a skin crease can be either oblique or zigzag, but never perpendicular to it...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29285955/novel-nitinol-stent-for-lesions-up-to-24-cm-in-the-superficial-femoral-and-proximal-popliteal-arteries-24-month-results-from-the-tigris-randomized-trial
#11
John R Laird, Thomas Zeller, Christian Loewe, Jack Chamberlin, Richard Begg, Peter A Schneider, Aravinda Nanjundappa, Frank Bunch, Scott Schultz, Stuart Harlin, Alexandra Lansky, Michael R Jaff
PURPOSE: To evaluate the safety and effectiveness of the TIGRIS stent for lesions up to 24 cm in the superficial femoral and proximal popliteal arteries (SFA/PPA). METHODS: This prospective, multicenter, randomized study enrolled 274 subjects at 36 sites in the United States and Europe. Subjects were randomly assigned in a 3:1 ratio to treatment with the TIGRIS stent (n=197; mean age 66.7±9.28 years; 141 men) or LifeStent (n=70; mean age 67.9±8.87 years; 49 men)...
December 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29284869/postoperative-ultrasound-guided-continuous-femoral-nerve-blockade-for-unilateral-total-knee-arthroplasty-a-comparison-of-0-125-bupivacaine-and-0-2-ropivacaine
#12
Sruthi C Babu, Gokuldas Menon, Bindu K Vasu, Mathew George, Jai Thilak, Sundaram Iyer
Context: Total knee arthroplasty (TKA) is associated with severe postoperative pain which increases morbidity and mortality. Aims: The aim of the study was to compare the analgesic efficacy and motor blockade of continuous infusion of 0.125% bupivacaine and 0.2% ropivacaine in femoral nerve block following unilateral TKA and to assess the effectiveness of femoral nerve block. Settings and Design: One hundred and fifty patients undergoing unilateral total knee replacement surgery were included in this prospective observational comparative study...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29284194/chronic-calf-pain-caused-by-fibroma-induced-chronic-inflammation-around-the-tibial-and-peroneal-nerves-that-was-misdiagnosed-as-centralized-neuropathic-pain-a-case-report
#13
Park Jiyoung, Ok Seong-Ho, Han Jeong Yeol, Park Miyeong, Seo Eun Hui, Kim Yeon A
INTRODUCTION: The etiology of calf pain varies widely; therefore, it is difficult to diagnose and requires careful history taking and physical examination by primary care unit physicians. Because ultrasonography is easy to perform, cheap, and readily available with physicians during a routine consultation, it is the first choice of modality for the evaluation of calf pain. However, simple inflammation around the nerve should also be considered as a possible etiology. Here we describe a 35-year-old man with chronic pain in the right calf that was actually caused by fibroma-induced chronic inflammation around the tibial and peroneal nerves but misdiagnosed as centralized neuropathic pain...
December 28, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29281955/drug-coated-ballons-for-femoro-popliteal-interventions
#14
Luca Tamburrini, Markus Vosseler, Christine Espinola-Klein
No abstract text is available yet for this article.
January 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29277060/does-additional-patella-tendon-shortening-influence-the-effects-of-multilevel-surgery-to-correct-flexed-knee-gait-in-cerebral-palsy-a-randomized-controlled-trial
#15
M C M Klotz, Britta K Krautwurst, K Hirsch, M Niklasch, M W Maier, S I Wolf, T Dreher
BACKGROUND: The aims of this study were to investigate if patellar tendon shortening (PTS) as a part of SEMLS (single event multilevel surgery) is effective for reduction of flexed knee gait in children with cerebral palsy (CP) and, if PTS leads to stiff knee gait. METHODS: In a randomized controlled study 22 children with flexed knee gait (age: 10.4 ± 2.6 years, GMFCS Level I-III) were randomized and allocated to two groups (1: SEMLS + PTS; 2: SEMLS no PTS): SEMLS was performed for correction of flexed knee gait either with or without additional PTS...
December 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29276109/determining-patient-risk-factors-associated-with-accelerated-growth-of-popliteal-artery-aneurysms
#16
Ryan S Cousins, David J Dexter, Sadaf S Ahanchi, Brandon C Cain, Obie M Powell, Sarah B Ongstad, Niraj M Parikh, Jean M Panneton
OBJECTIVE: The objective of this study was to determine the natural progression of popliteal artery aneurysms (PAAs) and clinical variables associated with their accelerated growth. METHODS: Retrospective chart review of 224 patients with encounters between January 2008 and May 2016 and with at least one PAA was conducted. From this group, 65 asymptomatic patients had either unilateral (n = 43) or bilateral (n = 22) PAAs that were observed for at least 1 year of medical management before intervention...
December 22, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29276108/sex-based-outcomes-of-lower-extremity-bypass-surgery-in-hemodialysis-patients
#17
Isibor Arhuidese, Amber Kernodle, Besma Nejim, Satinderjit Locham, Caitlin Hicks, Mahmoud B Malas
OBJECTIVE: The objective of this study was to compare conduit use and surgical outcomes of hemodialysis-dependent men and women after open lower extremity bypass surgery. METHODS: Using the United States Renal Data System, we studied all hemodialysis patients in the United States who underwent infrainguinal bypass surgery between January 1, 2006, and December 31, 2011. Univariate methods (χ2, analysis of variance) were employed to compare patient and bypass characteristics between men and women...
December 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29242066/external-polytetrafluoroethylene-reinforcement-of-varicose-autologous-vein-grafts-in-peripheral-bypass-surgery-produces-durable-bypass-function
#18
Achim Neufang, Christine Espinola-Klein, Savvas Savvidis, Walther Schmiedt, Alicia Poplawski, Christian Friedrich Vahl, Bernhard Dorweiler
OBJECTIVE: Use of autologous veins as peripheral bypass graft may become critical in the presence of significant varicose degeneration of the harvested vein. External support of such dilated veins with standard polytetrafluoroethylene (PTFE) prostheses was recommended as an option to use these veins for peripheral bypass. A single-center experience with this technique regarding long-term graft function, secondary reinterventions, and potential graft degeneration is presented. METHODS: Between January 1995 and January 2006, there were 54 patients with varicose veins who underwent 57 consecutive infrainguinal vein bypass operations with PTFE reinforcement in 57 limbs...
December 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29239204/john-hunter-s-operation-for-popliteal-aneurysm
#19
Harold Ellis
An aneurysm is defined as a "sac communicating with the lumen of an artery" and the treatment of the various types of this disease has intrigued surgeons through the ages. Aneurysms of the popliteal artery today are fairly uncommon. However, in the 18th century they were quite frequently encountered, many of them in coach drivers. We can only surmise that this was the result of repetitive trauma to the artery, already the seat of arteriosclerosis, against the rim at the top of the long leather riding boot which was worn at that time...
June 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29230344/cystic-adventitial-disease-of-popliteal-artery-with-venous-aneurysm-of-popliteal-vein-two-year-follow-up-after-surgery
#20
Koki Takizawa, Hiroshi Osawa, Atsuo Kojima, Samuel J K Abraham, Shigeru Hosaka
We report a rare case of cystic adventitial disease of popliteal artery with venous aneurysm of popliteal vein. A 46-year-old woman had sudden-onset intermittent claudication and coldness in her right leg. The right-sided ankle-brachial pressure index (ABI) was 1.01, but peripheral arterial pulsation was decreased at knee venting position. Computed tomography revealed simple cystic lesion of the popliteal artery and stenosis of the arterial lumen in this lesion. The patient was treated by complete resection of the cystic adventitial layer of popliteal artery...
2017: Case Reports in Vascular Medicine
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