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https://www.readbyqxmd.com/read/28934649/cooperative-stimulation-of-atherogenesis-by-lipopolysaccharide-and%C3%A2-palmitic-acid-rich-high-fat-diet-in-low-density-lipoprotein-receptor-deficient-mice
#1
Zhongyang Lu, Yanchun Li, Colleen W Brinson, Maria F Lopes-Virella, Yan Huang
BACKGROUND AND AIMS: Either lipopolysaccharide (LPS) or high-fat diet (HFD) enriched with saturated fatty acid (SFA) promotes atherosclerosis. In this study, we investigated the effect of LPS in combination with SFA-rich HFD on atherosclerosis and how LPS and SFA interact to stimulate inflammatory response in vascular endothelial cells. METHODS: Low-density lipoprotein receptor-deficient (LDLR(-/-)) mice were fed a low-fat diet (LFD), HFD with low palmitic acid (PA) (LP-HFD), or HFD with high PA (HP-HFD) for 20 weeks...
September 9, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28928169/individual-serum-saturated-fatty-acids-and-markers-of-chronic-subclinical-inflammation-the-insulin-resistance-atherosclerosis-study-iras
#2
Ingrid D Santaren, Steven M Watkins, Angela D Liese, Lynne E Wagenknecht, Marian J Rewers, Steven M Haffner, Carlos Lorenzo, Andreas Festa, Richard P Bazinet, Anthony J Hanley
Recent evidence has documented distinct effects of individual saturated fatty acids (SFA) on cardiometabolic outcomes, with potential protective effects from odd- and very long-chain (VLSFA) SFA. Cross-sectional and prospective associations of individual serum SFA (12:0, 14:0, 15:0, 16:0, 18:0, 20:0, 22:0, and total SFA) with proinflammatory biomarkers and adiponectin were investigated in 555 adults from the Insulin Resistance Atherosclerosis Study (IRAS). Principal components (PC) analysis of proinflammatory markers yielded 3 clusters: PC 1: fibrinogen, white cell count, CRP; PC 2: PAI-1, TNF-α; IL-18; PC 3: IL-6, IL-8...
September 19, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28917521/midterm-results-of-combined-intra-and-extra-articular-acl-reconstruction-compared-to-historical-acl-reconstruction-data-multicenter-study-of-the-francophone-society-of-arthroscopy
#3
P Imbert, S Lustig, C Steltzlen, C Batailler, P Colombet, F Dalmay, S Bertiaux, P D'ingrado, F P Ehkirch, M L Louis, R Pailhé, J C Panisset, B Schlaterrer, B Sonnery-Cottet, L Sigwalt, D Saragaglia, C Lutz
INTRODUCTION: During anterior cruciate ligament (ACL) reconstruction procedures, anterolateral reconstruction (ALR) can also be performed to improve the knee's rotational stability. However, the effectiveness of this supplemental technique and its impact on the risk of retears and on the onset of secondary degenerative changesare controversial. HYPOTHESIS: ALR improves control over the pivot shift, reduces the retear risk and delays the appearance of secondary degenerative lesions...
September 13, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28917520/short-term-complications-in-intra-and-extra-articular-anterior-cruciate-ligament-reconstruction-comparison-with-the-literature-on-isolated-intra-articular-reconstruction-a-multicenter-study-by-the-french-society-of-arthroscopy
#4
J C Panisset, R Pailhé, B Schlaterrer, L Sigwalt, B Sonnery-Cottet, C Lutz, S Lustig, C Batailler, S Bertiaux, F P Ehkirch, P Colombet, C Steltzlen, M L Louis, P D'ingrado, F Dalmay, P Imbert, D Saragaglia
INTRODUCTION: Lateral tenodesis (LT) is performed to limit the risk of iterative tear following anterior cruciate ligament (ACL) reconstruction in at-risk patients. By adding an extra procedure to isolated ACL graft, LT reconstruction increases operating time and may complicate postoperative course. The objective of the present study was to evaluate the rate of early complications. The study hypothesis was that associating ALL reconstruction to ACL reconstruction does not increase the complications rate found with isolated ACL reconstruction...
September 13, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28906398/abdominal-fat-distribution-measured-using-computed-tomography-is-associated-with-an-increased-risk-of-colorectal-adenoma-in-men
#5
Il-Kook Seo, Beom Jin Kim, Bomin Kim, Chang Hwan Choi, Jeong Wook Kim, Jae Gyu Kim, Se Kyung Chang, Hyun Kang
A few studies have shown inconsistent results regarding the association between the visceral fat proportion and colorectal adenomas. We aimed to investigate the association between abdominal fat distribution measured by computed tomography (CT) and colon adenoma.A total of 336 participants underwent physical examination, blood tests, colonoscopy, and abdominal computed tomography at Chung-Ang University Hospital. The associations between the obesity indicies (body mass index, visceral fat area (VFA), subcutaneous fat area (SFA), VFA-to-SFA ratio (VFA/SFA), and colorectal adenomas were evaluated...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28902254/condylectomy-and-surgery-first-approach-an-expedited-treatment-for-condylar-hyperplasia-in-a-patient-with-facial-asymmetry
#6
Diego Fernando López, Juan Fernando Aristizábal, Rosana Martínez-Smit
Condylar Hyperplasia (CH) is a self-limiting pathology condition that produces severe facial deformity at the expense of mandibular asymmetry. In this case report a 15-year-old female patient was diagnosed with Unilateral Condylar Hiperplasia (UCH) by mean of single-photon emission computed tomography (SPECT) and histological study. A high condylectomy in the right condyle was performed to stop the active status of the hyperplasia. A month after condylectomy, orthognathic jaw impaction and asymmetric mandibular setback surgery was performed with the Surgery First Approach (SFA)...
July 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28892713/stearic-acid-at-physiologic-concentrations-induces-in%C3%A2-vitro-lipotoxicity-in-circulating-angiogenic-cells
#7
Valentina Spigoni, Federica Fantuzzi, Alessia Fontana, Monia Cito, Eleonora Derlindati, Ivana Zavaroni, Miriam Cnop, Riccardo C Bonadonna, Alessandra Dei Cas
BACKGROUND AND AIMS: Saturated free fatty acids (SFAs) can induce lipotoxicity in different cells. No studies have investigated the effects of SFA in circulating angiogenic cells (CACs), which play a key role in endothelial repair processes. The aim of the study was to assess the effects of SFAs, specifically stearic acid (SA), on viability and function of CACs and to investigate potential underlying molecular mechanisms. METHODS: CACs were isolated from healthy subjects by established methods...
September 4, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28891401/revascularization-of-the-superficial-femoral-artery-with-paclitaxel-coated-balloon-for-claudication
#8
Celine Deloge, Evelyne Boesmans, Hendrik Van Damme, Jean-Olivier Defraigne
BACKGROUND: Percutaneous angioplasty of the superficial femoral artery (SFA) with paclitaxel-coated balloon, intended to reduce restenosis, has been proven safe and effective in recent randomized controlled trials. OBJECTIVE: To assess outcome results of angioplasty of the SFA with paclitaxel-coated balloon in claudicants in real-world practice of a single center. MATERIAL & METHODS: A continuous prospective cohort study of 53 claudicants (62 lower limbs) from January 2015 to December 2016...
September 11, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28890059/covered-stent-grafts-for-acquired-arterial-venous-fistulas-a-case-series
#9
Timur P Sarac, Lina Vargas, Vikram Kashyap, Jonathan Cardella, Cassius Ochoa Chaar
INTRODUCTION: Stent grafts have become the preferred method for treating abdominal aortic aneurysms (AAAs), but also have utility in treating other vasculopathies. In 2005, peripheral stent grafts were approved for treating superficial femoral artery (SFA) occlusive disease. This report describes our experience using covered stent grafts to treat acquired arterial venous fistulae (aAVF). METHODS: We reviewed the records of patients treated for aAVF with covered stent grafts...
September 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28889985/combined-intra-and-extra-articular-grafting-for-revision-acl-reconstruction-a-multicentre-study-by-the-french-arthroscopy-society-sfa
#10
M L Louis, P D'ingrado, F P Ehkirch, S Bertiaux, P Colombet, B Sonnery-Cottet, B Schlatterer, R Pailhé, J C Panisset, C Steltzlen, S Lustig, C Lutz, F Dalmay, P Imbert, D Saragaglia
BACKGROUND: A careful analysis of the reasons for ACL reconstruction failure is essential to selection of the optimal surgical revision technique designed to ensure good rotational stability and to minimise the risk of re-rupture. OBJECTIVE: To evaluate antero-lateral ligament (ALL) stabilisation during revision ACL reconstruction. HYPOTHESIS: ALL stabilisation during revision ACL reconstruction provides good rotational stabilitywithout increasing the risk of complications...
September 7, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28888526/posterior-shoulder-instability-managed-by-arthroscopic-acromial-pediculated-bone-block-technique
#11
Pierre Métais, Jean Grimberg, Philippe Clavert, Jean-François Kouvalchouk, François Sirveaux, Geoffroy Nourissat, Jérôme Garret, Pierre Mansat, Arnaud Godenèche
In posterior shoulder instability (recurrent dislocation, involuntary posterior subluxation or voluntary subluxation that has become involuntary), surgery may be considered in case of failure of functional treatment if there are no psychological contraindications. Acromial bone-block with pediculated deltoid flap, as described by Kouvalchouk, is an alternative to iliac bone-block, enabling triple shoulder locking by the blocking effect, the retention hammock provided by the deltoid flap, and posterior capsule repair...
September 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28873349/posterior-shoulder-instability-prospective-non-randomised-comparison-of-operative-and-non-operative-treatment-in-51-patients
#12
E Cruz-Ferreira, P Abadie, A Godenèche, P Mansat, P Clavert, P H Flurin
BACKGROUND: The management of posterior shoulder instability remains controversial. Consequently, for a symposium on this topic, the French Arthroscopy Society (SFA) conducted a prospective multicentre study comparing outcomes of operative and non-operative treatment. OBJECTIVE: To compare outcomes after operative versus non-operative treatment of posterior shoulder instability HYPOTHESIS: The surgical treatment of posterior shoulder instability may achieve better clinical outcomes than non-operative treatment in selected patients...
September 2, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28856549/elongation-of-very-long-chain-c24-fatty-acids-in-clarias-gariepinus-cloning-functional-characterization-and-tissue-expression-of-elovl4-elongases
#13
Angela Oboh, Juan C Navarro, Douglas R Tocher, Oscar Monroig
Elongation of very long-chain fatty acid 4 (Elovl4) proteins participate in the biosynthesis of very long-chain (>C24) saturated and polyunsaturated fatty acids (FA). Previous studies have shown that fish possess two different forms of Elovl4, termed Elovl4a and Elovl4b. The present study aimed to characterize both molecularly and functionally two elovl4 cDNA from the African catfish Clarias gariepinus. The results confirmed that C. gariepinus possessed two elovl4-like elongases with high homology to two previously characterized Elovl4 from Danio rerio, and thus they were termed accordingly as Elovl4a and Elovl4b...
August 30, 2017: Lipids
https://www.readbyqxmd.com/read/28842084/endoscopic-plantar-fasciotomy-deep-fascial-versus-superficial-fascial-approach-a-prospective-randomized-study
#14
Bilgehan Çatal, Mert Keskinbora, Mehmet Ali Uysal, Mustafa Şahin, Deniz Gulabi, Bahtiyar Demiralp
In the present randomized prospective study, 2 different surgical techniques of endoscopic plantar fascia release were compared. Of 547 patients with a diagnosis of plantar fasciitis, 46 with no response to conservative treatment for ≥6 months were included. Of the 46 patients, 5 were lost to follow-up. In group 1 (n = 21), plantar fascia release was performed using a deep fascial approach (DFA), and in group 2 (n = 20), the superficial fascial approach (SFA) with a slotted cannula technique was used...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28842077/evolution-and-current-use-of-technology-for-superficial-femoral-and-popliteal-artery-interventions-for-claudication
#15
REVIEW
Peter A Schneider
An important facet in caring for patients with claudication is the development of a plan for managing the technology available for superficial femoral artery (SFA) and popliteal artery interventions. Although this is a field in evolution, clinical experience and data are emerging that assist the clinician in making informed choices as to the best method of endovascular treatment. Algorithms for SFA and popliteal artery interventions are developing. Methods for assessing a wide range of technologies are discussed...
September 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28831957/favourable-nutrient-intake-and-displacement-with-long-term-walnut-supplementation-among-elderly-results-of-a-randomised-trial
#16
RANDOMIZED CONTROLLED TRIAL
Edward Bitok, Karen Jaceldo-Siegl, Sujatha Rajaram, Mercè Serra-Mir, Irene Roth, Tania Feitas-Simoes, Emilio Ros, Joan Sabaté
Older adults tend to require fewer energy content and higher levels of nutrients to promote and maintain optimal health. Regrettably, dietary variety and quality are known to decline with advancing age. We conducted a 2-year prospective, randomised, dietary intervention trial where we asked free-living elderly subjects (63-79 years) on self-selected habitual diets to incorporate walnuts daily into their diet (15 % energy). We then compared their nutrient intake with that of a similar group of concurrent participants on self-selected habitual diets but abstaining from walnut consumption (control)...
August 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28829991/pro-inflammatory-fatty-acid-profile-and-colorectal-cancer-risk-a-mendelian-randomisation-analysis
#17
Sebastian May-Wilson, Amit Sud, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hänninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, Laura Renkonen-Sinisalo, Anna Lepistö, Jan Böhm, Jukka-Pekka Mecklin, Nada A Al-Tassan, Claire Palles, Susan M Farrington, Maria N Timofeeva, Brian F Meyer, Salma M Wakil, Harry Campbell, Christopher G Smith, Shelley Idziaszczyk, Timothy S Maughan, David Fisher, Rachel Kerr, David Kerr, Michael N Passarelli, Jane C Figueiredo, Daniel D Buchanan, Aung K Win, John L Hopper, Mark A Jenkins, Noralane M Lindor, Polly A Newcomb, Steven Gallinger, David Conti, Fred Schumacher, Graham Casey, Lauri A Aaltonen, Jeremy P Cheadle, Ian P Tomlinson, Malcolm G Dunlop, Richard S Houlston
BACKGROUND: While dietary fat has been established as a risk factor for colorectal cancer (CRC), associations between fatty acids (FAs) and CRC have been inconsistent. Using Mendelian randomisation (MR), we sought to evaluate associations between polyunsaturated (PUFA), monounsaturated (MUFA) and saturated FAs (SFAs) and CRC risk. METHODS: We analysed genotype data on 9254 CRC cases and 18,386 controls of European ancestry. Externally weighted polygenic risk scores were generated and used to evaluate associations with CRC per one standard deviation increase in genetically defined plasma FA levels...
August 19, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28827338/in-situ-nano-to-microscopic-imaging-and-growth-mechanism-of-electrochemical-dissolution-e-g-corrosion-of-a-confined-metal-surface
#18
C Merola, H-W Cheng, K Schwenzfeier, K Kristiansen, Y-J Chen, H A Dobbs, J N Israelachvili, M Valtiner
Reactivity in confinement is central to a wide range of applications and systems, yet it is notoriously difficult to probe reactions in confined spaces in real time. Using a modified electrochemical surface forces apparatus (EC-SFA) on confined metallic surfaces, we observe in situ nano- to microscale dissolution and pit formation (qualitatively similar to previous observation on nonmetallic surfaces, e.g., silica) in well-defined geometries in environments relevant to corrosion processes. We follow "crevice corrosion" processes in real time in different pH-neutral NaCl solutions and applied surface potentials of nickel (vs...
August 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28823135/the-meat-quality-muscle-fiber-characteristics-and-fatty-acid-profile-in-jinjiang-and-f1-simmental%C3%A2-%C3%A3-%C3%A2-jinjiang-yellow-cattle
#19
Yue Zheng, Shizhi Wang, Peishi Yan
Objective: This study compared the meat quality, muscle fiber characteristics, and fatty acids between Jinjiang yellow cattle (JJ) and F1 Simmental × Jinjiang yellow cattle (SJ) which were offered the same diet. Methods: Six JJ and six SJ individuals were reared and fattened from 10 to 26 months of age. After feeding, the highrib (HR), ribeye (RB) and tenderloin (TL) samples were taken from the carcass for meat quality evaluations. Results: The results showed that growth performance of SJ was higher than that of JJ (higher live weight and average daily gain), and the hot carcass weight of SJ was higher than that of JJ (P < 0...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28820080/diet-quality-and-its-implications-on-the-cardio-metabolic-physical-and-general-health-of-older-men-the-concord-health-and-ageing-in-men-project-champ
#20
Rosilene V Ribeiro, Vasant Hirani, Alistair M Senior, Alison K Gosby, Robert G Cumming, Fiona M Blyth, Vasi Naganathan, Louise M Waite, David J Handelsman, Hal Kendig, Markus J Seibel, Stephen J Simpson, Fiona Stanaway, Margaret Allman-Farinelli, David G Le Couteur
The revised Dietary Guideline Index (DGI-2013) scores individuals' diets according to their compliance with the Australian Dietary Guideline (ADG). This cross-sectional study assesses the diet quality of 794 community-dwelling men aged 74 years and older, living in Sydney, Australia participating in the Concord Health and Ageing in Men Project; it also examines sociodemographic and lifestyle factors associated with DGI-2013 scores; it studies associations between DGI-2103 scores and the following measures: homoeostasis model assessment - insulin resistance, LDL-cholesterol, HDL-cholesterol, TAG, blood pressure, waist:hip ratio, BMI, number of co-morbidities and medications and frailty status while also accounting for the effect of ethnicity in these relationships...
July 2017: British Journal of Nutrition
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