keyword
MENU ▼
Read by QxMD icon Read
search

SFA

keyword
https://www.readbyqxmd.com/read/28107410/prognostic-impact-of-ct-quantified-muscle-and-fat-distribution-before-and-after-first-line-chemotherapy-in-lung-cancer-patients
#1
Johanna Nattenmüller, Raoul Wochner, Thomas Muley, Martin Steins, Simone Hummler, Birgit Teucher, Joachim Wiskemann, Hans-Ulrich Kauczor, Mark Oliver Wielpütz, Claus Peter Heussel
INTRODUCTION: Cachexia and sarcopenia are associated with poor outcome and increased chemotherapy-induced toxicity in lung cancer patients. However, the complex interplay of obesity, sarcopenia and cachexia, and its impact on survival in the context of first-line-chemotherapy is not yet understood. METHODS: In 200 consecutively recruited lung cancer patients (70 female, mean age 62y; mean BMI 25 kg/m2; median follow-up 15.97 months) with routine staging-CT before and after chemotherapy (CTX, mean interval: 4...
2017: PloS One
https://www.readbyqxmd.com/read/28100287/characterisation-of-fatty-acid-metabolism-in-different-insulin-resistant-phenotypes-by-means-of-stable-isotopes
#2
Ellen E Blaak
The obese insulin resistant and/or prediabetic state is characterised by systemic lipid overflow, mainly driven by an impaired lipid buffering capacity of adipose tissue, and an impaired capacity of skeletal muscle to increase fat oxidation upon increased supply. This leads to the accumulation of bioactive lipid metabolites in skeletal muscle interfering with insulin sensitivity via various mechanisms. In this review, the contribution of dietary v. endogenous fatty acids to lipid overflow, their extraction or uptake by skeletal muscle as well as the fractional synthetic rate, content and composition of the muscle lipid pools is discussed in relation to the development or presence of insulin resistance and/or an impaired glucose metabolism...
January 19, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28099162/thermography-based-blood-flow-imaging-in-human-skin-of-the-hands-and-feet-a-spectral-filtering-approach
#3
A A Sagaidachnyi, A V Fomin, D A Usanov, A V Skripal
The determination of the relationship between skin blood flow and skin temperature dynamics is the main problem in thermography-based blood flow imaging. Oscillations in skin blood flow are the source of thermal waves propagating from micro-vessels toward the skin's surface, as assumed in this study. This hypothesis allows us to use equations for the attenuation and dispersion of thermal waves for converting the temperature signal into the blood flow signal, and vice versa. We developed a spectral filtering approach (SFA), which is a new technique for thermography-based blood flow imaging...
January 18, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28099089/genotypic-characterization-of-quinolone-resistant-escherichia-coli-isolates-from-retail-food-in-morocco
#4
Kaotar Nayme, Abouddihaj Barguigua, Brahim Bouchrif, Bouchra Karraouan, Fatima El Otmani, Naima Elmdaghri, Khalid Zerouali, Mohammed Timinouni
This study was conducted to assess the retail food as a possible vehicle for antimicrobial resistant, particularly quinolones resistant and pathogenic Escherichia coli. We determined the prevalence and characteristics of nalidixic acid (Nal) resistant E. coli isolates from diverse retail food samples. In all, 70 (28%) of 250 E. coli isolates studied were Nal-resistant E. coli and 91% of these were multi-drug resistant. Plasmid mediated quinolone resistance genes were identified in 32 isolates, including aac(6')-Ib-cr (n = 16), qnrS1 (n = 11) and qnrB19 (n = 7)...
February 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/28093811/routine-use-of-distal-arterial-perfusion-in-pediatric-femoral-venoarterial-extracorporeal-membrane-oxygenation
#5
Christine A Schad, Brian P Fallon, Julie Monteagudo, Shunpei Okochi, Eva W Cheung, Nicholas J Morrissey, Angela V Kadenhe-Chiweshe, Gudrun Aspelund, Steven Stylianos, William Middlesworth
Lower-extremity ischemia is a significant complication in children on femoral venoarterial extracorporeal membrane oxygenation (VA ECMO). Our institution currently routinely uses distal perfusion catheters (DPCs) in all femoral arterial cannulations in attempts to reduce ischemia. We performed a single-center, retrospective review of pediatric patients supported with femoral VA ECMO from January 2005 to November 2015. The outcomes of patients with prophylactic DPC placement at cannulation (prophylactic DPC) were compared to a historical group with DPCs placed in response only to clinically evident ischemic changes (reactive DPC)...
January 2017: Artificial Organs
https://www.readbyqxmd.com/read/28091781/a-semifluorinated-alkane-f4h5-as-novel-carrier-for-cyclosporine-a-a-promising-therapeutic-and-prophylactic-option-for-topical-treatment-of-dry-eye
#6
Uta Gehlsen, Tobias Braun, Maria Notara, Sonja Krösser, Philipp Steven
PURPOSE: Cyclosporine A (Cs) has been used as effective topical therapy for inflammatory dry eye disease since more than a decade. However, due to its lipophilic character, Cs is formulated as emulsions or oily solutions for topical application. This experimental study aimed to test if the use of semifluorinated alkanes (SFAs) as a preservative-free, well-tolerated non-stinging or burning vehicle maintains or even improves the benefits of Cs in the topical therapy of dry-eye disease. METHODS: Desiccating stress was applied to C57BL/6 mice for 14 consecutive days to induce experimental dry-eye...
January 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28081347/virulence-factors-biofilm-forming-ability-and-antimicrobial-resistance-of-urinary-escherichia-coli-strains-isolated-from-hospitalized-patients
#7
Barbara Kot, Jolanta Wicha, Agata Grużewska, Małgorzata Piechota, Katarzyna Wolska, Maria Obrębska
BACKGROUND/AIM: Escherichia coli is the most frequent cause of urinary tract infections. We investigated the possible associations between the origin of strains, antimicrobial resistance, the presence of urovirulence factors, and biofilm-forming ability. MATERIALS AND METHODS: Antibiotic susceptibility of E. coli strains was tested by disk diffusion method. Hemagglutination assays were performed for phenotypic characterization of the cell surface. Multiplex PCR was used for detection of virulence genes and for determination of phylogenetic relationships...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28078712/comparative-study-on-fatty-acid-composition-of-olive-olea-europaea-l-with-emphasis-on-phytosterol-contents
#8
Ali Ozkan, Hassan Y Aboul-Enein, Muhittin Kulak, Recep Bindak
The present study was designed to determine the fatty acid composition and phytosterol contents of Turkish native olive cultivars namely (Kilis Yağlık and Nizip Yağlık cv.). In this context, olive fruits from thirty-four locations were sampled and then screened for their components in comparison. Fifteen different fatty acids were found in both olive oils. In the order of abundance, the most important ones were: oleic acid (18:1) > palmitic acid (16:0) > linoleic acid (18:2) > stearic acid (18:0)...
January 12, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28076787/impdh2-is-an-intracellular-target-of-the-cyclophilin-a-and-sanglifehrin-a-complex
#9
Khian Hong Pua, Dylan T Stiles, Mathew E Sowa, Gregory L Verdine
Natural products have demonstrated utility in the clinic and can also act as probes to understand complex cellular pathways. Sanglifehrin A (SFA) is a mixed polyketide and non-ribosomal peptide synthase natural product with sub-nano-molar affinity for its receptor cyclophilin A (PPIA). It has been shown to behave in vitro as an immune suppressant. Here, we identify inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) as an intracellular target of the PPIA-SFA binary complex. The formation of this ternary complex does not inhibit the enzymatic activity of IMPDH2...
January 10, 2017: Cell Reports
https://www.readbyqxmd.com/read/28076613/the-role-of-dietary-fatty-acid-intake-in-inflammatory-gene-expression-a-critical-review
#10
Daniela Mayumi Rocha, Josefina Bressan, Helen Hermana Hermsdorff
CONTEXT AND OBJECTIVE: Diet is an important modifiable factor involved in obesity-induced inflammation. We reviewed clinical trials that assessed the effect of consumption of different fatty acids on the expression of inflammation-related genes, such as cytokines, adipokines, chemokines and transcription factors. DESIGN AND SETTING: Narrative review study conducted at a research center. METHODS: This was a review on the effect of fat intake on inflammatory gene expression in humans...
January 5, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28072719/association-between-dietary-fat-intake-and-colorectal-adenoma-in-korean-adults-a-cross-sectional-study
#11
Jeehyun Kim, Seung-Won Oh, Young-Sun Kim, Hyuktae Kwon, Hee-Kyung Joh, Ji-Eun Lee, Danbee Park, Jae-Hong Park, Ah-Ryoung Ko, Ye-Ji Kim
The incidence of colorectal cancer is rapidly increasing in South Korea. It is important to clarify the association between colorectal cancer and diet, being one of the main modifiable risk factors, as such studies in the Korean population are lacking.A cross-sectional study was performed using data from participants who had undergone a screening colonoscopy and a nutritional assessment during a routine health check-up from January 2008 to December 2011. Dietary intake data were derived from 1-day food records; colorectal adenoma was histopathologically confirmed by biopsy during colonoscopy...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28070312/investigation-of-nutritional-properties-of-three-species-of-marine-turban-snails-for-human-consumption
#12
Roslizawati Ab Lah, Joshua Smith, Dale Savins, Ashley Dowell, Daniel Bucher, Kirsten Benkendorff
Turban snails (family Turbinidae) are gastropod molluscs that are harvested for human consumption yet little is known about the nutritional properties of these snails, particularly from Australian waters. This study compares the proximate composition (ash, moisture, protein, and lipid content), fatty acid profiles, mineral, and trace element content of three species of turbinid snails; Turbo militaris, Lunella undulata, and Lunella torquata from northern New South Wales, Australia. They were all found to have relatively high protein in their flesh (16...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28060199/management-of-skeletal-class-ii-malocclusion-by-surgery-first-approach
#13
Gagan Deep Kochar, Ashish Chakranarayan, Sanjay M Londhe, Bensy Varghese, Balakrishna Jayan, Sukhbir S Chopra, Rajat Mitra, Munish Verma
Surgery-first approach (SFA) has been a paradigm shift in the field of orthognathic surgery. Majority of the published cases that have been managed by this approach are of skeletal class III. This communication describes a patient of 18-year-old male diagnosed with skeletal class II malocclusion due to mandibular retognathism. He was managed with SFA and was using skeletal anchorage system to prevent postsurgical relapse. Bilateral saggital split ramus osteotomy was carried out to achieve the mandibular advancement of 7 mm...
January 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28049882/the-relationship-between-circulating-neutrophil-gelatinase-associated-lipocalin-and-early-alteration-of-metabolic-parameters-is-associated-with-dietary-saturated-fat-intake-in-non-diabetic-korean-women
#14
Ga Yoon Na, So Ra Yoon, Juhyun An, Rimkyo Yeo, Juhyun Song, Mi-Na Jo, Seongho Han, Oh Yoen Kim
Circulating neutrophil gelatinase-associated lipocalin (NGAL) is associated with obesity-related metabolic disorders. This study investigated the relationship between serum NGAL and early alteration of metabolic parameters in non-diabetic Korean women, particularly with respect to saturated fat (SFA) intake. Anthropometric parameters, fasting glycemic status, and levels of lipids, oxidative stress/inflammatory markers, and NGAL were measured in 82 non-diabetic Korean women [Super-healthy group (n=57) with 0 metabolic syndrome risk factor (MetS RF) and MetS-risk group (n=25) with MetS RF≥1]...
December 30, 2016: Endocrine Journal
https://www.readbyqxmd.com/read/28047025/su-g-201-04-can-the-dynamic-library-of-flap-applicators-replace-treatment-planning-in-surface-brachytherapy
#15
I Buzurovic, P Devlin, J Hansen, D O'Farrell, M Bhagwat, S Friesen, A Damato, T Harris, R Cormack
PURPOSE: Contemporary brachytherapy treatment planning systems-(TPS) include the applicator model libraries to improve digitization; however, the library of surface-flap-applicators-(SFA) is not incorporated into the commercial TPS. We propose the dynamic library-(DL) for SFA and investigate if such library can eliminate applicator reconstruction, source activation and dose normalization. METHODS: DL was generated for the SFA using the C++class libraries of the Visualization Toolkit-(VTK) and Qt-application framework for complete abstraction of the graphical interface...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046167/effects-of-marketing-group-and-production-focus-on-quality-and-variability-of-adipose-tissue-and-bellies-sourced-from-a-commercial-processing-facility
#16
M F Overholt, E K Arkfeld, K B Wilson, D A Mohrhauser, D A King, T L Wheeler, A C Dilger, S D Shackelford, D D Boler
Objectives were to determine the effects of marketing group on quality and variability of belly and adipose tissue quality traits of pigs sourced from differing production focuses (lean vs. quality). Pigs ( = 8,042) raised in 8 barns representing 2 seasons (cold and hot) were used. Three groups were marketed from each barn with 2 barns per production focus marketed per season. Data were collected on 7,684 carcasses at a commercial abattoir. Fresh belly characteristics, American Oil Chemists' Society iodine value (AOCS-IV), and near-infrared iodine value were measured on a targeted 50, 10, and 100% of carcasses, respectively...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28046152/divergent-selection-on-intramuscular-fat-in-rabbits-responses-to-selection-and-genetic-parameters
#17
M Martínez-Álvaro, P Hernández, A Blasco
A divergent selection experiment on intramuscular fat (IMF) was performed in rabbits. The aim of this study is to estimate the response to selection, the correlated responses in carcass and meat quality traits, and their genetic parameters. Selection criterion was the averaged phenotypic value of IMF measured at 9 wk of age in 2 full-sibs of the candidate. Traits considered were IMF, BW, chilled carcass weight, reference carcass weight, scapular and perirenal fat weights, carcass and meat color, pH, protein and fatty acid composition of meat...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28046146/prediction-of-porcine-carcass-iodine-value-based-on-diet-composition-and-fatty-acid-intake
#18
T A Kellner, G G Gourley, S Wisdom, J F Patience
The pig industry uses a variety of fat sources (FS) and fat levels (FL) in diets to increase energy content. The objective was to investigate the impact of FS and FL on rate and efficiency of gain, apparent total tract digestibility of dietary fat, and pork fat composition and test dietary predictors of carcass iodine value (IV). A total of 1,213 pigs (PIC 280 × PIC Camborough 42; PIC, Inc., Hendersonville, TN) with an initial BW of 32.0 ± 0.4 kg were randomly allotted to 1 of 6 dietary treatments on d 0...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28045026/saturated-palmitic-acid-induces-myocardial-inflammatory-injuries-through-direct-binding-to-tlr4-accessory-protein-md2
#19
Yi Wang, Yuanyuan Qian, Qilu Fang, Peng Zhong, Weixin Li, Lintao Wang, Weitao Fu, Yali Zhang, Zheng Xu, Xiaokun Li, Guang Liang
Obesity increases the risk for a number of diseases including cardiovascular diseases and type 2 diabetes. Excess saturated fatty acids (SFAs) in obesity play a significant role in cardiovascular diseases by activating innate immunity responses. However, the mechanisms by which SFAs activate the innate immune system are not fully known. Here we report that palmitic acid (PA), the most abundant circulating SFA, induces myocardial inflammatory injury through the Toll-like receptor 4 (TLR4) accessory protein MD2 in mouse and cell culture experimental models...
January 3, 2017: Nature Communications
https://www.readbyqxmd.com/read/28043742/selected-fatty-acids-as-biomarkers-of-exposure-to-microdoses-of-molluscicides-in-snails-helix-pomatia-gastropoda-pulmonata
#20
Danuta Kowalczyk-Pecka, Stanisław Pecka, Edyta Kowalczuk-Vasilev
Two stages of selection from a pool of 56 fatty acids analyzed in Helix pomatia yielded a set of 12 biomarker acids undergoing significant changes in contact with three microdoses of toxic substances, i.e. three molluscicides containing metaldehyde, methiocarb, and potassium chloride (PC). The proposed palette of acids, including saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and polyunsaturated fatty acids (PUFA), determined separately in the foot tissues and hepatopancreas of Gastropoda, can be used in ecotoxicological research as a reliable test of the effect of trace doses of stressors...
December 30, 2016: Environmental Pollution
keyword
keyword
18996
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"