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Skin excoriation

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https://www.readbyqxmd.com/read/28293501/management-of-a-complex-excoriation-disorder-induced-wound-with-a-viable-cryopreserved-placental-membrane
#1
Michael A Bain, Jennifer Vincent
Excoriation disorder (ED), also known as dermatotillomania, is a condition characterized by repeated "skin picking" that leads to the formation of skin lesions. Because of the similarity of its symptoms to obsessive compulsive disorder, ED is classified as a subcategory of obsessive compulsive disorder by Diagnostic and Statistical Manual of Mental Disorders Fifth Edition. Although the majority of the self-inflicted wounds are not clinically significant, many wounds lead to social and occupational dysfunction by becoming infected, chronic, and life threatening...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28253948/-long-term-outcomes-of-the-treatment-of-pediatric-femoral-shaft-fractures-treated-with-bryant-s-vertical-traction
#2
J Urban, P Toufar, M Kloub
PURPOSE OF THE STUDY The paper aimed to evaluate the long-term outcomes of the treatment of diaphyseal femur fractures in children treated with Bryant's vertical traction. Moreover, we also assessed the size of overgrowth in the injured femur. MATERIAL AND METHODS The study included 23 patients with 23 femoral shaft fractures treated with Bryant's vertical traction at our department in 2009-2014. The following parameters were assessed: sex, ïnjured side, weight, age, mechanism of injury, potential abuse, type of fracture, duration of traction, and total length of hospital stay...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28217465/cutaneous-manifestations-in-disorders-of-hepatobiliary-system
#3
Shashi K Godara, Devinder M Thappa, Biju Pottakkatt, Abdoul Hamide, Jagadisan Barath, Malathi Munisamy, Minu J Chiramel
BACKGROUND: Hepatobiliary diseases are associated with various mucocutaneous changes that are directly and indirectly associated with these diseases. There is a dearth of studies from India dealing with cutaneous manifestations in liver disorders. AIM: This study was conducted to know the spectrum of cutaneous changes and their correlation with liver function tests in patients with disorders of hepatobiliary system. METHODS: This was a descriptive study conducted among in patients and outpatients with primary hepatobiliary disorders at a tertiary care center in South India...
January 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28208894/case-report-of-youngest-successful-bilateral-cartilage-tympanoplasty-in-india
#4
Gaurav Ashish, Ankita Gupta
Paediatric Chronic Suppurative Otitis Media (CSOM) remains a challenge for the treating otologists. Usually, concurrent foci of infection lie in the oropharynx or nasopharynx and treating these eventually leads to resolution of ear discharge. However, refractory cases can be threatening in view of complications secondary to CSOM. A two year and 10-month-old child presented with recurrent profuse mucopurulent ear discharge which had been refractory to multiple medical treatment. Recently she had recurrent otitis external episodes with excoriations of canal skin...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28183072/alternative-therapies-for-excoriation-skin-picking-disorder-a-brief-update
#5
REVIEW
Julio Torales, Iván Barrios, Jorge Villalba
Context • Excoriation (skin picking) disorder is characterized by the need or urge to pick, scratch, pinch, touch, rub, scrub, squeeze, bite, or dig the skin, and it can be a perplexing condition for the inexperienced physician. Treatments include pharmacotherapy, psychotherapy, and alternative therapies. Alternative therapies for excoriation disorder and other body-focused repetitive behaviors include yoga, aerobic exercise, acupuncture, biofeedback, hypnosis, and inositol and N-acetylcysteine, among others...
January 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28168650/gsdma3-is-required-for-mammary-gland-development-in-mice
#6
Haiying Guo, Senlin Xu, Yingxin Liu, Yang Yang, Fang Deng, Yizhan Xing, Xiaohua Lian, Yuhong Li
AE (alopecia and excoriation) is a mouse mutant phenotype that harbours a mutation in Gsdma3. Gsdma3 has been reported to regulate the development of skin and hair follicles. However, its role in the mammary glands has not been reported. In this study, we found that descendants bred from an AE mother died within 12 days after birth. Then, we found that the expression of Gsdma3 varied among the developmental stages of mammary glands. Subsequently, we systematically studied the phenotype of the mammary glands of AE and wild-type mice, revealing that the mammary glands were smaller in AE mice...
February 6, 2017: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/28159725/topical-treatments-of-saussurea-costus-root-and-thuja-orientalis-l-synergistically-alleviate-atopic-dermatitis-like-skin-lesions-by-inhibiting-protease-activated-receptor-2-and-nf-%C3%AE%C2%BAb-signaling-in-hacat-cells-and-nc-nga-mice
#7
Hye Jeong Yang, Min Jung Kim, Suna Kang, Na Rang Moon, Da Sol Kim, Na Ra Lee, Kang Sung Kim, Sunmin Park
ETHNOPHARMACOLOGICAL RELEVANCE: The root of Saussurea costus (Aucklandia lappa Decne, Aucklandiae Radix, SC) and Thuja orientalis L. (TOL) have been traditionally used as anti-inflammatory agents in Korea. However, they have not been studied for the efficacy of atopic dermatitis (AD) treatment, a chronic inflammatory skin disease. We investigated the efficacy of topical applications with 1,3-butyleneglycol extracts of SC and TOL to alleviate the symptoms of AD. MATERIALS AND METHODS: HaCaT cells and the dorsal skin of Nc/Nga mice had a local exposure of house mite extracts and 2,4-dinitrochlorobenzene (DNCB), respectively...
January 31, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28129492/use-of-topiramate-in-skin-picking-disorder-a-pilot-study
#8
Mohammad Jafferany, Ferdnand C Osuagwu
Objective: Repetitive skin picking that culminates in skin lesions and excoriations has a fairly common prevalence and causes clinically significant distress. Myriads of agents have been used to treat the condition with no convincing results. Methods: Ten patients (8 women and 2 men) with skin-picking disorder (per DSM-5 criteria) were enrolled in the study. The study was conducted from December 1, 2013, to December 29, 2014. The patients were treated with 12-week open-label topiramate in a titrating-upward dose (25-200 mg/d)...
January 26, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28120675/bowel-management-systems-in-critical-care-a-service-evaluation
#9
Jennifer Ritzema
Aim Many patients who are critically ill develop faecal incontinence associated with diarrhoea, and require a bowel management system (BMS) to prevent skin excoriation. Following guidelines produced by the National Institute for Health and Care Excellence, early rehabilitation has resulted in a reduction in the number of days that patients receive mechanical ventilation. However, patients with a BMS are potentially mechanically ventilated for longer because they are cared for in bed. The aim of this evaluation was to investigate whether patients with a BMS are mechanically ventilated for longer than those without a BMS...
January 25, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28074213/-intrahepatic-cholestasis-of-pregnancy-rare-but-important
#10
REVIEW
A E Kremer, K Wolf, S Ständer
Intrahepatic cholestasis of pregnancy (ICP) is a liver-specific disorder occurring in approximately 0.5-2.0% of all pregnancies with a considerable variation in certain ethnic groups. ICP usually runs a benign course for the mother and is characterized by maternal pruritus mainly in the third trimester, elevated transaminases and fasting total serum bile salts and increased fetal adverse events. The etiology of ICP is only partially understood but seems to be multifactorial. Cholestasis-inducing effects of certain female sex hormones and their metabolites play an important role in genetically susceptible women...
January 10, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28063396/cold-pressor-pain-in-skin-picking-disorder
#11
Jon E Grant, Sarah A Redden, Samuel R Chamberlain
Excoriation (skin-picking) disorder (SPD) is a disabling, under-recognized condition in which individuals repeatedly pick at their skin, leading to noticeable tissue damage. There has been no examination as to whether individuals with SPD have different pain thresholds or pain tolerances compared to healthy counterparts. Adults with SPD were examined on a variety of clinical measures including symptom severity and functioning. All participants underwent the cold pressor test. Heart rate, blood pressure, and self-reported pain were compared between SPD participants (n=14) and healthy controls (n=14)...
March 2017: Psychiatry Research
https://www.readbyqxmd.com/read/27919277/a-study-of-long-term-complications-associated-with-enteral-ostomy-and-their-contributory-factors
#12
Umesh Jayarajah, Asuramuni M P Samarasekara, Dharmabandhu N Samarasekera
BACKGROUND: Complications of ostomy significantly affect the quality of life of ostomates. There is little evidence on the rate of long-term complications in ostomates, especially from the developing countries which include Sri Lanka. This study was aimed to describe the long-term complications of enteral ostomies and their contributory factors. METHODS: A retrospective analysis was carried out on 192 patients who underwent ostomy creation over a period of 5 years...
December 5, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27913138/compared-in%C3%A2-vivo-efficiency-of-nanoemulsions-unloaded-and-loaded-with-calixarene-and-soapy-water-in-the-treatment-of-superficial-wounds-contaminated-by-uranium
#13
Sophie Grivès, Guillaume Phan, Céline Bouvier-Capely, David Suhard, François Rebière, Michelle Agarande, Elias Fattal
No emergency decontamination treatment is currently available in the case of radiological skin contamination by uranium compounds. First responders in the workplace or during an industrial nuclear accident must be able to treat internal contamination through skin. For this purpose, a calixarene nanoemulsion was developed for the treatment of intact skin or superficial wounds contaminated by uranium, and the decontamination efficiency of this nanoemulsion was investigated in vitro and ex vivo. The present work addresses the in vivo decontamination efficiency of this nanoemulsion, using a rat model...
April 1, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27891435/a-study-of-clinical-profile-and-quality-of-life-in-patients-with-scabies-at-a-rural-tertiary-care-centre
#14
Pragya Ashok Nair, Rita Vipul Vora, Nidhi B Jivani, Shailee S Gandhi
INTRODUCTION: Scabies is a contagious disease primarily related to poverty and overcrowding, it rapidly spreads from person to person specially in people with poor hygiene. We come across many patients from rural areas with scabies. In India the incidence ranges from 13% to 59% in rural and urban areas. Many people complain of sleep disturbances and affection of work and leisure activities due to itching. Very few studies are done in India about the affection of quality of life in such patients...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27864837/risk-factors-for-non-purulent-leg-cellulitis-a-systematic-review-and-meta-analysis
#15
REVIEW
M Quirke, F Ayoub, A McCabe, F Boland, B Smith, R O'Sullivan, A Wakai
Non-purulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that is not associated with purulent drainage, discharge or abscess. The objective of this systematic review and meta-analysis (SRMA) was to identify and appraise all controlled observational studies that have examined risk factors for the development of non-purulent cellulitis of the leg (NPLC). A systematic literature search of electronic databases and grey literature sources was performed in July 2015. The Newcastle-Ottawa Scale (NOS) was used to assess methodological quality of included studies...
November 18, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27766914/n-acetylcysteine-in-the-treatment-of-psychiatric-disorders-current-status-and-future-prospects
#16
REVIEW
Alessandro Minarini, Silvia Ferrari, Martina Galletti, Nina Giambalvo, Daniela Perrone, Giulia Rioli, Gian Maria Galeazzi
N-acetylcysteine (NAC) is widely known for its role as a mucolytic and as an antidote to paracetamol overdose. There is increasing interest in the use of NAC in the treatment of several psychiatric disorders. The rationale for the administration of NAC in psychiatric conditions is based on its role as a precursor to the antioxidant glutathione, and its action as a modulating agent of glutamatergic, dopaminergic, neurotropic and inflammatory pathways. Areas covered: This study reviews the available data regarding the use of NAC in different psychiatric disorders including substance use disorders, autism, obsessive-compulsive spectrum disorders, schizophrenia, depression, bipolar disorder...
March 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27710988/outcome-of-loop-versus-divided-colostomy-in-the-management-of-anorectal-malformations
#17
COMPARATIVE STUDY
Osama Ibrahim Almosallam, Ali Aseeri, Saud Al Shanafey
BACKGROUND: Colostomy is a common part of the management of high anorectal malformation (ARM) in the pediatric population. OBJECTIVE: To evaluate whether the type of colostomy (loop vs divided) has an impact on outcome in patients with ARM. DESIGN: A retrospective study. SETTING: King Faisal Specialist Hospital and Research Center, a tertiary care center. PATIENTS AND METHODS: All patients who were managed with colostomy for ARM and had definitive repair during the period of January 2000 to December 2014...
September 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27688442/dermatoses-among-children-from-celebration-of-holi-the-spring-festival-in-india-a-cross-sectional-observational-study
#18
Sudip Kumar Ghosh, Debabrata Bandyopadhyay, Megha Agarwal, Olympia Rudra
BACKGROUND: "Holi" is a spring festival celebrated primarily in the Indian subcontinent and also abroad by expatriate Indians. It is a festival of colors, traditionally celebrated by mutual application of colors in different forms on a particular day of the year. These colors frequently comprise a range of synthetic dyes which have harmful effects on the skin and mucosae. Children take part in this colorful festival with much enthusiasm and vigor, making them prone to develop different "Holi"-related dermatoses...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27658538/obsessive-compulsive-skin-disorders-a-novel-classification-based-on-degree-of-insight
#19
Tian Hao Zhu, Mio Nakamura, Benjamin Farahnik, Michael Abrouk, Jason Reichenberg, Tina Bhutani, John Koo
Individuals with obsessive-compulsive features frequently visit dermatologists for complaints of the skin, hair, or nails, and often progress towards a chronic relapsing course due to the challenge associated with accurate diagnosis and management of their psychiatric symptoms. The current DSM-5 formally recognizes body dysmorphic disorder, trichotillomania, neurotic excoriation, and body focused repetitive behavior disorder as psychodermatological disorders belonging to the category of Obsessive Compulsive and Related Disorders...
September 23, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27579758/disseminated-cutaneous-sporotrichosis-associated-with-ocular-lesion-in-an-immunocompetent-patient
#20
Karina Bittencourt Medeiros, Luana Gomes Landeiro, Lucia Martins Diniz, Aloísio Falqueto
A 59-year-old female patient, previously healthy, immunocompetent, presented left bulbar conjunctiva lesions and nodular-ulcerated lesions on the arms and cervical region, besides left cervical and retroauricular lymphadenopathy. She had previous contact with domestic cats that excoriated her face. The diagnosis was conclusive of disseminated sporotrichosis through clinical and epidemiological history and cultures of skin and ocular secretions. It evolved with good response to oral antifungal therapy.
July 2016: Anais Brasileiros de Dermatologia
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