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Skin excoriation

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https://www.readbyqxmd.com/read/27919277/a-study-of-long-term-complications-associated-with-enteral-ostomy-and-their-contributory-factors
#1
Umesh Jayarajah, Asuramuni M P Samarasekara, Dharmabandhu N Samarasekera
BACKGROUND: Complications of ostomy significantly affect the quality of life of ostomates. There is little evidence on the rate of long-term complications in ostomates, especially from the developing countries which include Sri Lanka. This study was aimed to describe the long-term complications of enteral ostomies and their contributory factors. METHODS: A retrospective analysis was carried out on 192 patients who underwent ostomy creation over a period of 5 years...
December 5, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27913138/compared-in-vivo-efficiency-of-nanoemulsions-unloaded-and-loaded-with-calixarene-and-soapy-water-in-the-treatment-of-superficial-wounds-contaminated-by-uranium
#2
Sophie Grivès, Guillaume Phan, Céline Bouvier-Capely, David Suhard, François Rebière, Michelle Agarande, Elias Fattal
No emergency decontamination treatment is currently available in the case of radiological skin contamination by uranium compounds. First responders in the workplace or during an industrial nuclear accident must be able to treat internal contamination through skin. For this purpose, a calixarene nanoemulsion was developed for the treatment of intact skin or superficial wounds contaminated by uranium, and the decontamination efficiency of this nanoemulsion was investigated in vitro and ex vivo. The present work addresses the in vivo decontamination efficiency of this nanoemulsion, using a rat model...
November 29, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27891435/a-study-of-clinical-profile-and-quality-of-life-in-patients-with-scabies-at-a-rural-tertiary-care-centre
#3
Pragya Ashok Nair, Rita Vipul Vora, Nidhi B Jivani, Shailee S Gandhi
INTRODUCTION: Scabies is a contagious disease primarily related to poverty and overcrowding, it rapidly spreads from person to person specially in people with poor hygiene. We come across many patients from rural areas with scabies. In India the incidence ranges from 13% to 59% in rural and urban areas. Many people complain of sleep disturbances and affection of work and leisure activities due to itching. Very few studies are done in India about the affection of quality of life in such patients...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27864837/risk-factors-for-non-purulent-leg-cellulitis-a-systematic-review-and-meta-analysis
#4
REVIEW
M Quirke, F Ayoub, A McCabe, F Boland, B Smith, R O'Sullivan, A Wakai
Non-purulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that is not associated with purulent drainage, discharge or abscess. The objective of this systematic review and meta-analysis (SRMA) was to identify and appraise all controlled observational studies that have examined risk factors for the development of non-purulent cellulitis of the leg (NPLC). A systematic literature search of electronic databases and grey literature sources was performed in July 2015. The Newcastle-Ottawa Scale (NOS) was used to assess methodological quality of included studies...
November 18, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27766914/n-acetylcysteine-in-the-treatment-of-psychiatric-disorders-current-status-and-future-prospects
#5
Alessandro Minarini, Silvia Ferrari, Martina Galletti, Nina Giambalvo, Daniela Perrone, Giulia Rioli, Gian Maria Galeazzi
N-acetylcysteine (NAC) is widely known for its role as a mucolytic and as an antidote to paracetamol overdose. There is increasing interest in the use of NAC in the treatment of several psychiatric disorders. The rationale for the administration of NAC in psychiatric conditions is based on its role as a precursor to the antioxidant glutathione, and its action as a modulating agent of glutamatergic, dopaminergic, neurotropic and inflammatory pathways. Areas covered: This study reviews the available data regarding the use of NAC in different psychiatric disorders including substance use disorders, autism, obsessive-compulsive spectrum disorders, schizophrenia, depression, bipolar disorder...
November 2, 2016: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27710988/outcome-of-loop-versus-divided-colostomy-in-the-management-of-anorectal-malformations
#6
Osama Ibrahim Almosallam, Ali Aseeri, Saud Al Shanafey
BACKGROUND: Colostomy is a common part of the management of high anorectal malformation (ARM) in the pediatric population. OBJECTIVE: To evaluate whether the type of colostomy (loop vs divided) has an impact on outcome in patients with ARM. DESIGN: A retrospective study. SETTING: King Faisal Specialist Hospital and Research Center, a tertiary care center. PATIENTS AND METHODS: All patients who were managed with colostomy for ARM and had definitive repair during the period of January 2000 to December 2014...
September 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27688442/dermatoses-among-children-from-celebration-of-holi-the-spring-festival-in-india-a-cross-sectional-observational-study
#7
Sudip Kumar Ghosh, Debabrata Bandyopadhyay, Megha Agarwal, Olympia Rudra
BACKGROUND: "Holi" is a spring festival celebrated primarily in the Indian subcontinent and also abroad by expatriate Indians. It is a festival of colors, traditionally celebrated by mutual application of colors in different forms on a particular day of the year. These colors frequently comprise a range of synthetic dyes which have harmful effects on the skin and mucosae. Children take part in this colorful festival with much enthusiasm and vigor, making them prone to develop different "Holi"-related dermatoses...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27658538/obsessive-compulsive-skin-disorders-a-novel-classification-based-on-degree-of-insight
#8
Tian Hao Zhu, Mio Nakamura, Benjamin Farahnik, Michael Abrouk, Jason Reichenberg, Tina Bhutani, John Koo
Individuals with obsessive-compulsive features frequently visit dermatologists for complaints of the skin, hair, or nails, and often progress towards a chronic relapsing course due to the challenge associated with accurate diagnosis and management of their psychiatric symptoms. The current DSM-5 formally recognizes body dysmorphic disorder, trichotillomania, neurotic excoriation, and body focused repetitive behavior disorder as psychodermatological disorders belonging to the category of Obsessive Compulsive and Related Disorders...
September 23, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27579758/disseminated-cutaneous-sporotrichosis-associated-with-ocular-lesion-in-an-immunocompetent-patient
#9
Karina Bittencourt Medeiros, Luana Gomes Landeiro, Lucia Martins Diniz, Aloísio Falqueto
A 59-year-old female patient, previously healthy, immunocompetent, presented left bulbar conjunctiva lesions and nodular-ulcerated lesions on the arms and cervical region, besides left cervical and retroauricular lymphadenopathy. She had previous contact with domestic cats that excoriated her face. The diagnosis was conclusive of disseminated sporotrichosis through clinical and epidemiological history and cultures of skin and ocular secretions. It evolved with good response to oral antifungal therapy.
July 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27501029/interleukin-il-31-induces-in-cynomolgus-monkeys-a-rapid-and-intense-itch-response-that-can-be-inhibited-by-an-il-31-neutralizing-antibody
#10
K E Lewis, M S Holdren, M F Maurer, S Underwood, B Meengs, S H Julien, K A Byrnes-Blake, J A Freeman, T R Bukowski, A C Wolf, N B Hamacher, M W Rixon, S R Dillon
BACKGROUND: Overexpression or administration of interleukin 31 (IL-31) has been shown to induce a profound itch response in mice and dogs. The chronic pruritus observed in mouse IL-31 transgenic mice results in the development of skin lesions and alopecia through excoriation from excessive scratching, a condition similar to that observed in patients with atopic dermatitis (AD). OBJECTIVE: To test whether IL-31 induces pruritus in non-human primates and, if so, whether treatment with an anti-IL-31 neutralizing monoclonal antibody (mAb) can block the response...
August 8, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27498656/successful-treatment-of-a-chronic-eczema-in-a-48-year-old-female-with-dr-michaels%C3%A2-eczitinex%C3%A2-and-itchinex%C3%A2-product-family-a-case-report
#11
M Tirant, P Anderson, P Bayer, J Hercogovấ, M Fioranelli, S Gianfaldoni, A A Chokoeva, G Tchernev, U Wollina, F Novotny, M G Roccia, G K Maximov, K França, T Lotti
We report the case of a 48-year-old female with chronic atopic eczema who responded successfully to Dr Michaels® (Eczitinex® and Itchinex®) product family. The patient had a 41-year history of atopic eczema and presented with erythematous, excoriated lesions with telangiectasia and scattered purpura (bruising) covering 90% of her body surface area. The patient also regularly suffered blepharitis with red, itchy, watery eyes. The patient was treated with Dr Michaels® (Eczitinex® and Itchinex®) ointment and herbal supplements and presented total resolution of the atopic eczema and underlying inflammation within 6 weeks...
April 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27376752/-pruritus-in-systemic-diseases-common-and-rare-etiologies
#12
A E Kremer, T Mettang
Chronic pruritus is a symptom of various internal disorders. In contrast to dermatological diseases, pruritus does not present with primary skin alterations in these patients. However, intense scratching may cause secondary skin changes such as abrasion, excoriation, prurigo nodularis, or in rare cases even scaring. The most common internal medicine causes for chronic pruritus are chronic kidney disease, hepatobiliary and hematological disorders as well as adverse drug reactions. Pruritus is less commonly seen in patients with endocrine or metabolic diseases, malabsorption syndromes, infectious diseases and solid tumors...
August 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27286530/-a-self-report-instrument-for-the-assessment-of-dermatillomania-reliability-and-validity-of-the-german-skin-picking-scale-revised
#13
Christina Gallinat, Nancy J Keuthen, Matthias Backenstrass
At least since the introduction of the official diagnosis Excoriation (Skin-Picking) Disorder in the DSM-5 [1], dermatillomania is an important and growing field of research. Despite the high importance currently a huge lack of German assessment instruments exists. Aim of the present study was the examination of the psychometric properties of the German translation of the Skin Picking Scale-Revised [2]. For this purpose an open online study has been conducted. The analysis of N=2 065 data sets indicated a high internal consistency with Cronbachs Alpha being 0...
June 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27144210/abdominal-skin-rash-after-tace-due-to-non-target-embolization-of-hepatic-falciform-artery
#14
Prashant Nagpal, Mitesh Bhalala, Aditi Vidholia, Rahul Sao, Nisha Sharma, Dhruv Mehta, Sam McCabe, Roxana Bodin
Transcatheter arterial chemoembolization (TACE) is a well-recognized procedure for management of hepatocellular carcinoma. We present a 54-year-old man who presented with a periumbilical maculopapular skin rash that developed after an otherwise uneventful TACE procedure. A retrospective review of imaging was consistent with non-target embolization of the hepatic falciform artery (HFA). He was treated with oral non-steroidal antiinflammatory medication for 3 weeks with improvement, but had slight skin induration and an excoriated papule at 6-month follow-up...
April 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27143352/a-systematic-review-and-meta-analysis-of-psychiatric-treatments-for-excoriation-skin-picking-disorder
#15
Robert R Selles, Joseph F McGuire, Brent J Small, Eric A Storch
OBJECTIVE: While individual trials suggest benefit of interventions for excoriation (skin-picking) disorder (ExD), limited systematic evaluation of treatments, or their collective benefit, exists. METHODS: The present study examined the current state of treatments for ExD in a systematic review and meta-analysis and explored potential treatment moderators. Twelve trials were identified for review, including five with a control condition. Of these, nine were eligible to be included in the meta-analysis (three with a control)...
July 2016: General Hospital Psychiatry
https://www.readbyqxmd.com/read/27141573/kyrle-s-disease-in-a-patient-with-delusions-of-parasitosis
#16
M Tampa, Maria Isabela Sârbu, Clara Matei, Daniela E Mihăilă, T D Potecă, Simona-Roxana Georgescu
Acquired perforating disorders are a group of uncommon skin conditions characterized by transepidermal extrusion of altered dermal material, most often associated with diabetes mellitus and chronic kidney failure. Delusional parasitosis is a primary psychiatric disorder in which affected patients have fixed, false beliefs that their skin is infested by parasites, in the absence of any evidence supporting their statements. A 69 year old malepatient addressed the Dermatology Department for a skin eruption consisting of multiple umbilicated keratotic papules with a generalized distribution...
January 2016: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/27108868/pyoderma-gangrenosum-after-trauma-in-a-dog
#17
Noriyuki Nagata, Masashi Yuki, Ryota Asahina, Hiroki Sakai, Sadatoshi Maeda
A 12-year-old male entire Miniature Pinscher presented with excoriations at various body sites, progressively forming ulcers and enlarging until arrested by treatment. Based on the clinical presentation and histopathological analyses, sterile neutrophilic dermatosis was suspected. Therefore, the dog was started on prednisolone. Marked improvement was achieved with prednisolone treatment, suggesting a diagnosis of pyoderma gangrenosum (PG). Transcription levels of cytokine mRNA in lesional skin before and after treatment from this dog were quantified by real-time RT-PCR...
September 1, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27008151/how-to-perform-a-tracheostomy-dressing-and-inner-cannula-change
#18
Nicola Credland
RATIONALE AND KEY POINTS: Proactive tracheostomy management increases patient safety and reduces adverse events. ▶ A cleaning regimen performed every four hours reduces the risk of a blocked tracheostomy cannula, complete tube occlusion and respiratory arrest. ▶ Sterile tracheostomy dressings allow secretions from the stoma to be absorbed and prevent pressure damage from the tracheostomy tube. ▶ Regular dressing changes and skin inspection permit timely identification of inflammatory processes and skin excoriation, enabling prompt treatment to be instigated...
March 23, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27007062/n-acetylcysteine-in-the-treatment-of-excoriation-disorder-a-randomized-clinical-trial
#19
Jon E Grant, Samuel R Chamberlain, Sarah A Redden, Eric W Leppink, Brian L Odlaug, Suck Won Kim
IMPORTANCE: Excoriation (skin-picking) disorder (SPD) is a disabling, underrecognized condition in which individuals repeatedly pick at their skin, leading to noticeable tissue damage. To date, there has been no clearly effective pharmacologic or psychological treatment for SPD. OBJECTIVE: To determine whether N-acetylcysteine, an amino acid that appears to restore extracellular glutamate concentration in the nucleus accumbens, will be more effective than placebo in reducing compulsive picking behavior...
May 1, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/26972998/incontinence-associated-dermatitis-new-insights-into-an-old-problem
#20
David Voegeli
Incontinence-associated dermatitis (IAD) is a common skin disorder seen in patients with incontinence. Typically IAD presents as inflammation of the skin surface characterised by redness, and in extreme cases, swelling and blister formation. If untreated this usually rapidly leads to excoriation and skin breakdown, which may subsequently become infected by the skin flora. While this is a common condition encountered in all areas of nursing practice, gaps remain in our understanding of the many contributing factors...
March 10, 2016: British Journal of Nursing: BJN
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