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https://www.readbyqxmd.com/read/29793189/effects-of-exposure-to-anti-vaping-public-service-announcements-among-current-smokers-and-dual-users-of-cigarettes-and-electronic-nicotine-delivery-systems
#1
Andy S L Tan, Vaughan W Rees, Justin Rodgers, Emeka Agudile, Natasha A Sokol, Kyeungyeun Yie, Ashley Sanders-Jackson
INTRODUCTION: Anti-vaping public service announcements (PSAs) are intended to discourage vaping or use of electronic nicotine delivery systems (ENDS). However, vaping portrayals in PSAs may have unintended effects if they increase smoking or vaping urges. This study examined benefits and unintended effects of anti-vaping PSAs with vapor portrayals on smoking and vaping-related outcomes. METHODS: Young adult smokers (N = 171) and dual users (N = 122) aged 21-30 years were randomly assigned to view: 1) anti-vaping PSAs with vapor; 2) anti-vaping PSAs without vapor; 3) physical activity PSAs; or 4) anti-smoking PSAs with smoking cues...
May 16, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29793135/accuracy-of-magnetic-resonance-venography-in-diagnosing-cerebral-venous-sinus-thrombosis
#2
Liansheng Gao, Weilin Xu, Tao Li, Xiaobo Yu, Shenglong Cao, Hangzhe Xu, Feng Yan, Gao Chen
OBJECTIVES: The non-specific clinical manifestations and lack of effective diagnostic techniques have made cerebral venous sinus thrombosis (CVST) difficult to recognize and easy to misdiagnose. Several studies have suggested that different types of magnetic resonance venography (MRV) have advantages in diagnosing CVST. We conducted this meta-analysis to assess the accuracy of MRV in identifying CVST. MATERIAL AND METHODS: We searched the Embase, PubMed, and Chinese Biomedical (CBM) databases comprehensively to retrieve eligible articles up to Mar 31, 2018...
May 17, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29793128/convolutional-neural-networks-for-seizure-prediction-using-intracranial-and-scalp-electroencephalogram
#3
Nhan Duy Truong, Anh Duy Nguyen, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Samuel Ippolito, Omid Kavehei
Seizure prediction has attracted growing attention as one of the most challenging predictive data analysis efforts to improve the life of patients with drug-resistant epilepsy and tonic seizures. Many outstanding studies have reported great results in providing sensible indirect (warning systems) or direct (interactive neural stimulation) control over refractory seizures, some of which achieved high performance. However, to achieve high sensitivity and a low false prediction rate, many of these studies relied on handcraft feature extraction and/or tailored feature extraction, which is performed for each patient independently...
May 7, 2018: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29793126/effect-of-manual-therapy-versus-proprioceptive-neuromuscular-facilitation-in-dynamic-balance-mobility-and-flexibility-in-field-hockey-players-a-randomized-controlled-trial
#4
Gemma V Espí-López, Susana López-Martínez, Marta Inglés, Pilar Serra-Añó, Marta Aguilar-Rodríguez
OBJECTIVES: To compare the effectiveness of a specific Manual Therapy (MT) protocol applied to field hockey players (FHP), versus a Proprioceptive Neuromuscular Facilitation (PNF) protocol, in the improvement of dynamic balance, active range of movement and lumbar flexibility one-week and four-weeks after the treatment. DESIGN: Randomized controlled trial. Participants were assigned to 2 groups: MT and PNF. 30 min' sessions were performed once a week for three weeks...
April 22, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29793106/microplastics-in-mussels-sampled-from-coastal-waters-and-supermarkets-in-the-united-kingdom
#5
Jiana Li, Christopher Green, Alan Reynolds, Huahong Shi, Jeanette M Rotchell
Global contamination of the marine environment by plastic has led to the discovery of microplastics in a range of marine species, including those for human consumption. In this study, the presence of microplastics and other anthropogenic debris in seawater and mussels (Mytilus edulis) from coastal waters of the U.K., as well as supermarket sources, was investigated. These were detected in all samples from all sites with spatial differences observed. Seawater samples taken from 6 locations (in triplicates) displayed 3...
May 21, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29793077/fmri-classification-method-with-multiple-feature-fusion-based-on-minimum-spanning-tree-analysis
#6
Hao Guo, Pengpeng Yan, Chen Cheng, Yao Li, Junjie Chen, Yong Xu, Jie Xiang
Resting state functional brain networks have been widely studied in brain disease research. Conventional network analysis methods are hampered by differences in network size, density and normalization. Minimum spanning tree (MST) analysis has been recently suggested to ameliorate these limitations. Moreover, common MST analysis methods involve calculating quantifiable attributes and selecting these attributes as features in the classification. However, a disadvantage of these methods is that information about the topology of the network is not fully considered, limiting further improvement of classification performance...
May 21, 2018: Psychiatry research. Neuroimaging
https://www.readbyqxmd.com/read/29793070/intradialytic-blood-pressure-pattern-recognition-based-on-density-peak-clustering
#7
Feng Wang, Jing-Yi Zhou, Yu Tian, Yu Wang, Ping Zhang, Jiang-Hua Chen, Jing-Song Li
End-stage renal disease (ESRD) is the final stage of chronic kidney disease (CKD) and requires hemodialysis (HD) for survival. Intradialytic blood pressure (IBP) measurements are necessary to ensure patient safety during HD treatments and have critical clinical and prognostic significance. Studies on IBP measurements, especially IBP patterns, are limited. All related studies have been based on a priori knowledge and artificially classified IBP patterns. Therefore, the results were influenced by subjective concepts...
May 21, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29793053/aggressive-fluid-and-sodium-restriction-in-decompensated-heart-failure-with-preserved-ejection-fraction-results-from-a-randomized-clinical-trial
#8
Karina Sanches Machado d'Almeida, Eneida Rejane Rabelo-Silva, Gabriela Corrêa Souza, Melina Maria Trojahn, Sofia Louise Santin Barilli, Graziella Aliti, Luís Eduardo Rohde, Andreia Biolo, Luís Beck-da-Silva
OBJECTIVES: Sodium and fluid restriction is commonly prescribed for heart failure patients. However, its role in the treatment of heart failure with preserved ejection fraction (HFpEF) remains unclear. The aim of this study was to compare the effect of a diet with sodium and fluid restriction with an unrestricted diet in patients admitted for decompensated HFpEF. METHODS: Patients were randomized to a diet with sodium (0.8 g/d) and fluid (800 mL/d) restriction (intervention group [IG]) or an unrestricted diet (control group [CG]) and followed for 7 d or hospital discharge...
March 21, 2018: Nutrition
https://www.readbyqxmd.com/read/29793033/expression-of-anabaena-sensory-rhodopsin-is-influenced-by-different-codons-of-seven-residues-at-the-n-terminal-region
#9
Otgontuya Tsogbadrakh, Ah Reum Choi, Kwang-Hwan Jung
Microbial rhodopsins are well-known seven-transmembrane proteins that have been extensively studied for their structure and function. These retinal-binding proteins can be divided into two types. Type I is microbial rhodopsin, and type II (visual pigment) is expressed mostly in mammalian eyes. The two primary functions of type I rhodopsin are ion pumping activity and sensory transduction. Anabaena sensory rhodopsin (ASR) is a microbial rhodopsin with a specific function of photosensory transduction. ASR is expressed at moderate levels in Escherichia coli, but its expression level is lower compared to the general green light absorbing proteorhodopsin (GPR)...
May 21, 2018: Protein Expression and Purification
https://www.readbyqxmd.com/read/29793031/cloning-overexpression-and-purification-of-a-gene-of-unknown-function-of-prophage-loci-from-candidatus-liberibacter-asiaticus-the-destructive-bacterial-pathogen-of-huanglongbing-disease-in-citrus-plants
#10
Duangtip Sudhan, Thamrongjet Puttamuk, Supachai Vuttipongchaikij, Pitak Chuawong
Citrus Huanglongbing (HLB) or citrus greening is one of the most destructive diseases affecting citrus industry worldwide. The causal agent in Asia is a phloem-limited, Gram-negative bacterium, 'Candidatus Liberibacter asiaticus' (CLas). Within the genome of CLas lies prophage regions, classified as Type-A, B, C, and D. In particular, Type-D has been indicated to correlate with the blotchy-mottle symptoms of citrus trees. Here we reported the cloning, overexpression, and purification of the ORF1, an open reading frame from the partial Type-D region of CLas obtained from an infected lime tree (Citrus aurantifolia Swingle)...
May 21, 2018: Protein Expression and Purification
https://www.readbyqxmd.com/read/29793011/thoracic-endovascular-aortic-repair-tevar-versus-best-medical-treatment-bmt-for-high-risk-type-b-intramural-hematoma-imh-a-systematic-review-of-clinical-studies
#11
REVIEW
Lin Li, Yuanyong Jiao, Junjie Zou, Xiwei Zhang, Hongyu Yang, Hao Ma
BACKGROUND: To date , thoracic endovascular aortic repair (TEVAR) for type B aortic dissection is favorable, but TEVAR for type B IMH remains uncertain. There are numerous clinical (eg, refractory pain) and radiologic (eg, IMH thickness) factors that are reported to be associated with IMH progression, challenging the treatment for high-risk type B IMH with high risk factors in clinical practice. OBJECTIVE: To perform a systematic review of clinical studies to investigate outcomes of TEVAR+BMT and BMT in the treatment of high-risk type B IMH ...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29793002/rasch-analysis-suggested-that-items-from-the-template-for-intervention-description-and-replication-tidier-checklist-can-be-summed-to-create-a-score
#12
Tie P Yamato, Chris G Maher, Bruno T Saragiotto, Mark J Catley, Anne M Moseley
OBJECTIVE: The aim of this study was to construct and evaluate a summary score of reporting completeness based on the Template for Intervention Description and Replication (TIDieR). STUDY DESIGN AND SETTING: We included 200 reports published in 2013 randomly selected from the Physiotherapy Evidence Database (PEDro). We summed the scores for the 12 items for the intervention and control groups for each trial in order to create a summary score from 0 to 24. Rasch analysis was used to investigate the item hierarchy, category function and reliability of the TIDieR checklist and determine the extent to which the summary score can be considered an interval-level measure...
May 21, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29792940/a-randomized-control-trial-to-determine-the-effectiveness-and-physiological-effects-of-spinal-manipulation-and-spinal-mobilization-compared-to-each-other-and-a-sham-condition-in-patients-with-chronic-low-back-pain-study-protocol-for-the-relief-study
#13
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
May 21, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29792936/efficient-detection-of-copy-number-mutations-in-pms2-exons-with-close-homologs-detection-of-copy-number-variants-in-3-pms2-exons
#14
Daniel S Herman, Christina Smith, Chang Liu, Cecily P Vaughn, Selvi Palaniappan, Colin C Pritchard, Brian H Shirts
Detection of 3' PMS2 copy number mutations that cause Lynch syndrome is difficult, because of highly homologous pseudogenes. To improve the accuracy and efficiency of clinical screening for these mutations, we developed a new method to analyze standard capture-based, next-generation sequencing data to identify deletions and duplications in PMS2 exons 9 to 15. The approach captures sequence reads using PMS2 targets, maps sequences randomly amongst regions with equal mapping quality, counts reads aligned to homologous exons and introns, and flags read count ratios outside of empirically derived reference ranges...
May 21, 2018: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/29792935/lp533401-restores-bone-health-in-5-6-nephrectomized-rats-by-a-decrease-of-gut-derived-serotonin-and-regulation-of-serum-phosphate-through-the-inhibition-of-phosphate-co-transporters-expression-in-the-kidneys
#15
Dariusz Pawlak, Beata Znorko, Bartlomiej Kalaska, Tomasz Domaniewski, Radosław Zawadzki, Paweł Lipowicz, Michał Doroszko, Urszula Łebkowska, Piotr Grabowski, Krystyna Pawlak
LP533401 is an orally bioavailable small molecule that inhibits tryptophan hydroxylase-1, an enzyme responsible for the synthesis of gut-derived serotonin (GDS). Recently, we showed that increased GDS in rats with chronic kidney disease (CKD) affected bone strength and metabolism. We tested the hypothesis that treatment with LP533401 could reverse CKD-induced bone loss in uremia. Sixteen weeks after 5/6 nephrectomy, rats were randomized into untreated (CKD), treated with vehicle (VEH) and LP533401 at a dose of 30 or 100 mg/kg daily for 8 weeks...
May 21, 2018: Bone
https://www.readbyqxmd.com/read/29792925/change-in-patient-reported-outcomes-in-patients-with-and-without-mechanical-symptoms-undergoing-arthroscopic-meniscal-surgery-a-prospective-cohort-study
#16
Kenneth Pihl, Aleksandra Turkiewicz, Martin Englund, L Stefan Lohmander, Uffe Jørgensen, Nis Nissen, Jeppe Schjerning, Jonas B Thorlund
OBJECTIVE: Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older (>40 years) patients with preoperative mechanical symptoms improved more in patient-reported outcomes after meniscal surgery than those without mechanical symptoms. DESIGN: Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up...
May 21, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29792887/auditory-priming-improves-neural-synchronization-in-auditory-motor-entrainment
#17
Jewel E Crasta, Michael H Thaut, Charles W Anderson, Patricia L Davies, William J Gavin
Neurophysiological research has shown that auditory and motor systems interact during movement to rhythmic auditory stimuli through a process called entrainment. This study explores the neural oscillations underlying auditory-motor entrainment using electroencephalography. Forty young adults were randomly assigned to one of two control conditions, an auditory-only condition or a motor-only condition, prior to a rhythmic auditory-motor synchronization condition (referred to as combined condition). Participants assigned to the auditory-only condition (auditory-first group) listened to 400 trials of auditory stimuli presented every 800ms, while those in the motor-only condition (motor-first group) were asked to tap rhythmically every 800ms without any external stimuli...
May 21, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29792885/effects-of-vasopressin-on-neural-processing-of-infant-crying-in-expectant-fathers
#18
Sandra Thijssen, Anna E Van 't Veer, Jurriaan Witteman, Willemijn M Meijer, Marinus H van IJzendoorn, Marian J Bakermans-Kranenburg
In a randomized, double blind, placebo-controlled, within-subject magnetic resonance imaging study, we examined the effect of 20 IU intranasal vasopressin on the neural processing of infant crying in 25 fathers-to-be. We explored whether familial background modulates vasopressin effects, and whether vasopressin differentially affects cry processing coupled with neutral or emotional contextual information. Participants listened to cries accompanied by neutral ('this is an infant') or emotional ('this infant is sick/bored') contextual information, and neutral control sounds ('this is a saw')...
May 21, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29792882/utilization-of-automated-performance-metrics-to-measure-surgeon-performance-during-robotic-vesicourethral-anastomosis-and-methodical-development-of-a-training-tutorial
#19
Jian Chen, Paul J Oh, Nathan Cheng, Ankeet Shah, Jeremy Montez, Anthony Jarc, Liheng Guo, Inderbir S Gill, Andrew J Hung
PURPOSE: To develop and validate automated performance metrics (APMs) to measure surgeon performance of vesicourethral anastomosis (VUA) during robotic-assisted radical prostatectomy (RRP). Furthermore, we seek to methodically develop a standardized training tutorial for the robotic VUA. MATERIALS AND METHODS: APMs (motion tracking and system events data) and synchronized surgical video were captured during the RRP. Non-automated performance metrics (NAPMs) were manually annotated by video review...
May 21, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29792839/patient-choice-of-adjunctive-non-pharmacologic-pain-management-during-first-trimester-abortion-a-randomized-controlled-trial
#20
Mary Tschann, Jennifer Salcedo, Reni Soon, Bliss Kaneshiro
OBJECTIVE: To determine if offering patients a choice of adjunctive non-pharmacologic pain management during first-trimester aspiration abortion results in lower pain scores than seen without offering these additional measures. STUDY DESIGN: We enrolled women receiving first-trimester aspiration abortion at the University of Hawai'i. We randomized patients to standard care (control), or standard care plus a choice of non-pharmacologic pain management options (intervention)...
May 21, 2018: Contraception
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