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Pancreatic ultrasound

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https://www.readbyqxmd.com/read/29028511/a-pictorial-review-of-diagnostic-pitfalls-of-developmental-anomalies-and-variants-in-pancreatic-imaging
#1
REVIEW
Jong Eun Lee, Sang Soo Shin, Shin Jung Kim, Suk Hee Heo, Hyo Soon Lim, Jin Woong Kim, Yong Yeon Jeong
Developmental anomalies and anatomic variants of the pancreas vary widely, and most of them are encountered incidentally during radiologic evaluation. However, some of these anomalies and variants are potentially pathologic and may cause various clinical presentations in childhood or adulthood. The early identification of these entities in various imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance (MR) imaging would be valuable in making correct diagnoses and, in turn, preventing unnecessary additional procedures...
September 19, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29026598/endoscopic-ultrasound-guided-fine-needle-aspiration-of-pancreatic-lesions-with-22-versus-25-gauge-needles-a-meta-analysis
#2
Antonio Facciorusso, Elisa Stasi, Marianna Di Maso, Gaetano Serviddio, Mohammed Salah Ali Hussein, Nicola Muscatiello
BACKGROUND: Robust data in favour of a clear superiority of 22 versus 25 Gauge needles for endoscopic ultrasound-guided fine needle aspiration are still lacking. OBJECTIVE: We aimed to compare the diagnostic sensitivity, specificity and safety of these two needles for endoscopic ultrasound-guided fine needle aspiration of solid pancreatic lesions. METHODS: A computerized bibliographic search was restricted to randomized controlled trials only...
October 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29018018/acute-pancreatitis-as-an-unusual-presentation-of-primary-splenic-lymphoma
#3
Elisa Gravito-Soares, Marta Gravito-Soares, José Eduardo Pina-Cabral, Luis Tomé
A 51-year-old man with no relevant medical history presents to the emergency department complaining of a recent worsening of few months upper abdominal pain with back radiation and postprandial fullness, without B symptoms. Laboratory analysis showed hyperamylasaemia, elevated lactate dehydrogenase and inflammatory parameters. Abdominal ultrasonography revealed a heterogeneous solid mass in the spleen/splenic hilum with pancreatic parenchyma continuity and no biliary tract dilation or gallstones. A mild acalculous acute pancreatitis diagnosis was made...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29016384/lumen-apposing-metal-stents-lamss-for-drainage-of-pancreatic-and-gallbladder-collections-a-meta-analysis
#4
Dennis Han, Sumant Inamdar, Calvin W Lee, Larry S Miller, Arvind J Trindade, Divyesh V Sejpal
BACKGROUND AND AIMS: Endoscopic ultrasound-guided transmural drainage using lumen apposing metal stents (LAMSs) is becoming a popular and promising therapeutic approach for drainage of intra-abdominal fluid collections. There has been an increasing number of studies evaluating LAMS for drainage of pancreatic pseudocysts (PP), walled-off pancreatic necrosis (WOPN), and gallbladder (GB) drainage. The aim of this meta-analysis is to analyze the literature to date regarding the clinical success, technical success, and adverse events of LAMS in treatment of pancreatic fluid collections and GB drainage...
October 9, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28991562/imaging-and-screening-of-pancreatic-cancer
#5
REVIEW
Kristine S Burk, Grace C Lo, Michael S Gee, Dushyant V Sahani
Given the low disease prevalence of both exocrine and endocrine cancers in the general population, screening is not recommended. However, in as many as 25% of cases there is a precursor lesion or an identifiable genetic predisposition. For these patients at increased risk, screening with imaging is recommended. Multidetector computed tomography, MR imaging or magnetic resonance cholangiopancreatography, and endoscopic ultrasound examination can be used as screening modalities. Recent advances in dual energy CT and total body MR imaging have increased the suitability of these noninvasive modalities as first-line imaging screening options...
November 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28988410/a-case-of-macrocystic-type-serous-cystic-neoplasm-with-repeated-pancreatitis-within-a-short-period-of-time
#6
Akihiko Kida, Yukihiro Shirota, Tsuyoshi Suda, Yuji Houdo, Katsuaki Sato, Tokio Wakabayashi
The patient was a 39-year-old woman in whom computed tomography (CT) in 201X had revealed a pancreatic cystic neoplasm (PCN) of 4.3 cm in diameter in the pancreatic body. In June 201X + 3, the patient consulted our hospital regarding severe acute pancreatitis. The condition improved through treatment with large-volume fluid replacement and continuous regional arterial infusion therapy. Thereafter, acute pancreatitis recurred twice, in November 201X + 3 and in January 201X + 4. During an 8-month period, acute pancreatitis occurred three times...
October 7, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28987419/endoscopic-ultrasound-guided-pancreatic-cyst-ablation-more%C3%A2-peril-than-promise
#7
EDITORIAL
Patrick Yachimski, Shyam Varadarajulu
No abstract text is available yet for this article.
October 4, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28986569/algorithm-guided-outlining-of-105-pancreatic-cancer-liver-metastases-in-ultrasound
#8
Alexander Hann, Lucas Bettac, Mark M Haenle, Tilmann Graeter, Andreas W Berger, Jens Dreyhaupt, Dieter Schmalstieg, Wolfram G Zoller, Jan Egger
Manual segmentation of hepatic metastases in ultrasound images acquired from patients suffering from pancreatic cancer is common practice. Semiautomatic measurements promising assistance in this process are often assessed using a small number of lesions performed by examiners who already know the algorithm. In this work, we present the application of an algorithm for the segmentation of liver metastases due to pancreatic cancer using a set of 105 different images of metastases. The algorithm and the two examiners had never assessed the images before...
October 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28985853/the-falciform-ligament-as-a-graft-for-portal-superior-mesenteric-vein-reconstruction-in-pancreatectomy
#9
Yang Zhiying, Tan Haidong, Liu Xiaolei, Sun Yongliang, Si Shuang, Liu Liguo, Xu Li, Manar Atyah
BACKGROUND: Tumor invasion or adherence to the portal vein-superior mesenteric vein (PV/SMV) may be encountered during pancreatic surgery. In such cases, venous resection and reconstruction might be required for complete resection of the tumor. We report an innovative technique in which the graft for PV/SMV reconstruction was made with the falciform ligament. METHODS: Between May 2011 and July 2016, PV/SMV reconstruction with a falciform ligament graft was performed in 10 cases during pancreatectomy...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28983505/comparison-of-endoscopic-ultrasound-guided-fine-needle-aspiration-by-capillary-action-suction-and-no-suction-methods-a-randomized-blinded-study
#10
Rinkesh K Bansal, Narendra S Choudhary, Rajesh Puri, Saurabh K Patle, Suraj Bhagat, Mukesh Nasa, Amit Bhasin, Haimanti Sarin, Mridula Guleria, Randhir Sud
BACKGROUND AND STUDY AIM : Different types of endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) techniques are used in clinical practice; the best method in terms of outcome has not been determined. The aim of the study was to compare the diagnostic adequacy of aspirated material, and the cytopathological and EUS morphological features between capillary action, suction, and no-suction FNA methods. PATIENTS AND METHODS:  This was a prospective, single-blinded, randomized study conducted at a tertiary care hospital...
October 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28979722/pancreatic-adenosquamous-carcinoma-and-intraductal-papillary-mucinous-neoplasm-in-a-cdkn2a-germline-mutation-carrier
#11
Fernando Martínez de Juan, María Reolid Escribano, Carmen Martínez Lapiedra, Fernanda Maia de Alcantara, María Caballero Soto, Ana Calatrava Fons, Isidro Machado
A 69-year-old woman from a kindred with familial atypical multiple mole melanoma and carrier of a germline mutation in CDKN2A, presented with abdominal pain caused by a solid-cystic pancreatic mass. The patient had an abdominal computed tomography three years before in which there was no evidence of pancreatic lesion. The endoscopic ultrasound guided fine needle aspiration showed adenocarcinoma with squamous component. After surgical resection the final diagnosis was adenosquamous pancreatic carcinoma (ASPC) arising in an intraductal papillar mucinous neoplasm (IPMN)...
September 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28979721/desmoid-type-fibromatosis-a-case-report-with-an-unusual-etiology
#12
Syed Faisal Jafri, Obada Obaisi, Gerardo G Vergara, Joe Cates, Jaswinder Singh, Jennifer Feeback, Harathi Yandrapu
Desmoid type fibromatosis (DTF) is a rare, locally invasive, non-metastasizing soft tissue tumor. We report an interesting case of DTF involving the pancreatic head of a 54-year-old woman. She presented with intermittent dysphagia and significant weight loss within a 3-mo period. Laboratory findings showed mild elevation of transaminases, significant elevation of alkaline phosphatase and direct hyperbilirubinemia, indicating obstructive jaundice. Computerized tomography of the abdomen revealed a mass in the head of the pancreas, dilated common bile duct, and dilated pancreatic duct...
September 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28979714/novel-and-supplementary-management-of-pancreatic-fluid-collections-endoscopic-ultrasound-guided-drainage
#13
Si-Jie Hao, Wei-Jia Xu, Yang Di, Lie Yao, Hang He, Feng Yang, Chen Jin, Liang Zhong, De-Liang Fu
AIM: To compare efficacy and safety of endoscopic ultrasound (EUS)-guided and surgical drainage in pancreatic fluid collection management. METHODS: Data were obtained retrospectively from January 2012 to December 2016. Patients with pancreatic fluid collection were performed EUS-guided or surgical procedure. Main outcome measures including clinical efficiency, complication, duration of procedures, hospital stay and cost were analyzed. RESULTS: Thirty-six patients were enrolled into the study, including 14 in endoscopic group while 22 in the surgical group...
September 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28975036/marked-paraneoplastic-basophilia-accompanying-eosinophilia-in-a-cat-with-alimentary-t-cell-lymphoma
#14
Maria Balan, Aimee Hope, Joseph Cassidy, Maureen McCullough, Peter J O'Brien
CASE SUMMARY: A 5-year-old male neutered domestic shorthair cat was referred with a history of persistent pyrexia, pica, soft faeces, inappetence, intermittent vomiting, mild-to-moderate granulocytosis and mild hypercalcaemia. No significant improvement was noted after antibiotic and corticosteroid treatment, except that the hypercalcaemia resolved. Physical examination, including thoracic auscultation, and abdominal and peripheral lymph node palpation, were unremarkable. On admission, haematology revealed moderate leukocytosis (36...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/28974904/interventional-endoscopic-ultrasound-for-a-symptomatic-pseudocyst-secondary-to-gastric-heterotopic-pancreas
#15
Hang-Bin Jin, Lei Lu, Jian-Feng Yang, Qi-Feng Lou, Jing Yang, Hong-Zhang Shen, Xiao-Wei Tang, Xiao-Feng Zhang
Heterotopic pancreas (HP) is a relatively uncommon entity that is defined as pancreatic tissue without a true anatomical or vascular connection to the pancreas. HP does not cause symptoms in most cases but can occasionally produce various manifestations, including nausea, vomiting, abdominal pain, and even heterotopic pancreatitis. Here, we report an unusual case in which heterotopic pancreatitis complicated by the formation of a pseudocyst that caused gastric outlet obstruction was diagnosed based on serum hyperamylasemia and findings from endoscopic ultrasonography (EUS)-guided fine needle aspiration (EUS-FNA) cytology...
September 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28971378/endoscopic-ultrasound-guided-transmural-drainage-of-walled-off-pancreatic-necrosis-in-patients-with-portal-hypertension-and-intra-abdominal-collaterals
#16
Surinder S Rana, Ravi Sharma, Sobur Uddin Ahmed, Rajesh Gupta
BACKGROUND: Acute necrotizing pancreatitis (ANP) is complicated with segmental portal hypertension (PHT) and formation of venous collaterals. Presence of collaterals in vicinity of endoscopic transmural tract can lead to potentially catastrophic situation. Here, we report safety and outcome of EUS-guided transmural drainage of walled-off pancreatic necrosis (WOPN) in patients with PHT and intra-abdominal collaterals. METHODS: Retrospective analysis of collected database of patients (n=18; age 40...
October 2, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28970734/how-to-treat-intestinal-obstruction-due-to-malignant-recurrence-after-whipple-s-resection-for-pancreatic-head-cancer-description-of-2-new-endoscopic-techniques
#17
Christina Mouradides, Alaa Taha, Ivan Borbath, Pierre H Deprez, Tom G Moreels
The prognosis of pancreatic cancer remains poor, even after initial surgical therapy. Local recurrence after Whipple's pancreatico-duodenectomy may lead to intestinal obstruction at the level of the afferent limb or the alimentary limb. Endoscopic insertion of a self-expandable metal stent (SEMS) into the intestinal malignant stricture is the preferred method of choice for palliation. We describe two new endoscopic techniques to treat a malignant intestinal obstruction with the insertion of a SEMS into the afferent limb and the alimentary limb...
September 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28970292/preoperative-next-generation-sequencing-of-pancreatic-cyst-fluid-is-highly-accurate-in-cyst-classification-and-detection-of-advanced-neoplasia
#18
Aatur D Singhi, Kevin McGrath, Randall E Brand, Asif Khalid, Herbert J Zeh, Jennifer S Chennat, Kenneth E Fasanella, Georgios I Papachristou, Adam Slivka, David L Bartlett, Anil K Dasyam, Melissa Hogg, Kenneth K Lee, James Wallis Marsh, Sara E Monaco, N Paul Ohori, James F Pingpank, Allan Tsung, Amer H Zureikat, Abigail I Wald, Marina N Nikiforova
OBJECTIVE: DNA-based testing of pancreatic cyst fluid (PCF) is a useful adjunct to the evaluation of pancreatic cysts (PCs). Mutations in KRAS/GNAS are highly specific for intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), while TP53/PIK3CA/PTEN alterations are associated with advanced neoplasia. A prospective study was performed to evaluate preoperative PCF DNA testing. DESIGN: Over 43-months, 626 PCF specimens from 595 patients were obtained by endoscopic ultrasound (EUS)-fine needle aspiration and assessed by targeted next-generation sequencing (NGS)...
September 28, 2017: Gut
https://www.readbyqxmd.com/read/28969083/additional-k-ras-mutation-analysis-and-plectin-1-staining-improve-the-diagnostic-accuracy-of-pancreatic-solid-mass-in-eus-guided-fine-needle-aspiration
#19
Joo Kyung Park, Woo Hyun Paik, Byeong Jun Song, Ji Kon Ryu, Min A Kim, Jin Myung Park, Sang Hyub Lee, Yong-Tae Kim
BACKGROUND: One of the major genetic alterations in pancreatic ductal adenocarcinoma (PDAC) is the point mutation of K-ras gene. Plectin-1 was also recently identified as PDAC specific biomarker. The aim of this study was to investigate the improvement of diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) by using additional K-ras mutation analysis and Plectin-1 staining in patients with pancreatic mass. METHODS: A total of 85 study patients with pancreatic mass underwent EUS-FNA and the final diagnoses were as follows; PDACs: 70 patients, pancreas neuroendocrine tumor: 4, metastasis to pancreas: 5, autoimmune pancreatitis: 3, chronic pancreatitis: 1, tuberculous lymphadenitis: 1, pseudocyst: 1...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28963386/possible-congenital-dilatation-of-the-pancreatic-duct
#20
Abhijeet Tavare, Alex N Gordon-Weeks, Helen Bungay, Michael Silva
The main pancreatic duct can become dilated in a number of conditions. We describe a patient with gross dilatation of the main pancreatic duct without evidence of causative underlying pathology suggesting congenital dilatation of the pancreatic duct. A 36-year-old man presented with signs of intestinal obstruction and a history of surgery for congenital pyloric stenosis. Incidental findings on CT showed a massively dilated main pancreatic duct. On MRI there was no duct irregularity or solid mural nodule, making a main duct intraductal papillary mucinous neoplasm unlikely...
September 28, 2017: BMJ Case Reports
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