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Pancreatic ultrasound

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https://www.readbyqxmd.com/read/28323638/fast-lesion-mapping-during-hifu-treatment-using-harmonic-motion-imaging-guided-focused-ultrasound-hmigfus-in-vitro-and-in-vivo
#1
Yang Han, Shutao Wang, Thomas Payen, Elisa Konofagou
The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic motion imaging guided focused ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS...
March 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28318763/pancreatic-carcinosarcoma-a-case-report-highlighting-computed-tomography-characteristics
#2
Steven Mszyco, Leslie Teng, Joseph Annunziata, Matthew S Hartman
Primary pancreatic carcinosarcoma is a rare and malignant neoplasm arising within the pancreas. With fewer than a dozen cases ever reported, the recognition and treatment of this rare phenomenon can be difficult. We describe the case of an 85-year-old man who presented with vague right upper quadrant and epigastric abdominal pain and was found to have a pancreatic mass on ultrasound and computed tomography. The patient underwent open pancreaticoduodenectomy and was found to have pancreatic carcinosarcoma on microscopic evaluation...
January 27, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28317208/current-status-of-interventional-endoscopic-ultrasound
#3
REVIEW
Shomei Ryozawa, Naotaka Fujita, Atsushi Irisawa, Yoshiki Hirooka, Tetsuya Mine
Endoscopic ultrasound (EUS) is being used increasingly in the management of pancreatic fluid collection, biliary and pancreatic duct drainage in cases of failed endoscopic retrograde cholangiopancreatography, drainage of the gallbladder, and other conditions. The role of interventional EUS is rapidly expanding and new interventions are continuously emerging. The development of devices could be a major breakthrough in the field of interventional EUS. New devices would enable the expansion of its role even further and prompt its widespread use in clinical practice...
March 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28317015/evaluation-of-the-2015-aga-guidelines-on-pancreatic-cystic-neoplasms-in-a-large-surgically-confirmed-multicenter-cohort
#4
Phillip S Ge, V Raman Muthusamy, Srinivas Gaddam, Diana-Marie Jaiyeola, Stephen Kim, Alireza Sedarat, Timothy R Donahue, Lindsay Hosford, Robert H Wilson, David P Grande, Rajesh N Keswani, Vladimir M Kushnir, Daniel Mullady, Steven A Edmundowicz, Dayna S Early, Srinadh Komanduri, Sachin Wani, Rabindra R Watson
Background and study aims The American Gastroenterological Association (AGA) recently published guidelines for the management of asymptomatic pancreatic cystic neoplasms (PCNs). We aimed to evaluate the diagnostic characteristics of the AGA guidelines in appropriately recommending surgery for malignant PCNs. Patients and methods A retrospective multicenter study was performed of patients who underwent endoscopic ultrasound (EUS) for evaluation of PCNs who ultimately underwent surgical resection from 2004 - 2014...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28315030/endoscopic-management-of-pancreatic-cysts
#5
REVIEW
Michael J Bartel, Massimo Raimondo
Management of pancreatic cystic lesions relies on patients' clinical presentation, imaging, and endoscopic ultrasound. Current research in basic science, radiology, and endoscopy is evolving and making progress in this condition which is relatively common in the general population. This review focuses on the recent endoscopic ultrasound approaches to the diagnosis of these pancreatic disorders.
March 17, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28297832/-effects-of-high-intensity-focused-ultrasound-on-apoptosis-associated-gene-expression-in-xenografts-with-human-pancreatic-cancer
#6
L L Hong, Z Guo, W G Xing, H P Yu, C F Liu, X L Yang, H L Wang
Objective: To identify the expression of apoptosis-associated genes of high- intensity focused ultrasound(HIFU) in xenograft with human pancreatic cancer. Methods: Mice implated with human pancreatic cancer cells (YY-1) were divided into HIFU group or control group. Tumor cell apoptosis was verified by TUNEL. The expression of the apoptosis-associated genes was analyzed by Agilent Human Gene Expression. Selected genes was validated by quantitative real-time PCR(RT-PCR)and Western blot. Results: The rate of tumor cell apoptosis in HIFU group was higher than that of control group at 7, 14 days after HIFU treatment ((63...
March 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28295664/small-pancreatic-insulinoma-successful-endoscopic-ultrasound-guided-radiofrequency-ablation-in-a-single-session-using-a-22g-fine-needle
#7
Francesc Bas-Cutrina, Domingo Bargalló, Joan B Gornals
A 63-year-old woman, morbidly obese, with clinical symptoms of periodic hypoglycemic episodes, was diagnosed with an insulinoma in pancreatic body that had not been detected by previous computed tomography and magnetic resonance. This neuroendocrine tumour was identified by EUS as a hypoechoic lesion with some iso-hyperechoic tracts, measuring 9 x 10 mm, and 4-5 mm from splenic vessels (Figure 1a). This article is protected by copyright. All rights reserved.
March 14, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28275961/high-diagnostic-yield-of-endoscopic-ultrasound-guided-fine-needle-aspiration-without-an-on-site-cytopathologist
#8
Shyam Sunder Sharma, Mukesh Jain, Sudhir Maharshi
BACKGROUND: Endoscopic ultrasound (EUS) is a well-established modality in diagnosing and staging of various neoplastic and non-neoplastic lesions. Its accuracy further increases in the presence of an on-site cytopathologist. There is a paucity of data on diagnostic yield of EUS-guided fine needle aspiration cytology (FNAC) without an on-site cytopathologist. METHODS: Retrospective data were analyzed at SMS Medical College, Jaipur, from January 2014 to October 2015...
March 9, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28273606/an-impressive-choledochal-cyst-and-its-surgical-resection
#9
Nhu Thao Nguyen Galván, Kayla Kumm, Dor Yoeli, Ellen Witte, Michael Kueht, Ronald Timothy Cotton, Abbas Rana, Christine A O'Mahony, John A Goss
INTRODUCTION: Choledochal cysts are rare congenital dilations of the biliary tree that can present with non-specific symptoms such as abdominal pain, jaundice, cholelithiasis and pancreatitis. Although most commonly identified in children, they can be found in the adult population. However, because of the non-specific symptoms, this diagnosis may be difficult to make in the adult. A physician therefore must keep this diagnosis within their differential, as it may arise in an unexpected patient population who may present with a convoluted work up...
February 21, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28272682/xanthogranulomatous-pancreatitis-a-rare-case-defying-clinical-radiological-and-tumor-marker-diagnostics-with-a-review-of-literature
#10
Kavita Gaur, Shramana Mandal, Nidhi Mahajan, Sandeep Saluja, Satyajit Godhi
Xanthogranulomatous inflammation of the pancreas is an extremely rare entity mimicking pancreatic neoplasia. Elevation of tumor markers has seldom been reported in xanthogranulomatous inflammation of the pancreas, rendering the diagnosis difficult and highlighting the importance of a meticulous histopathological examination. A 58-year-old male presented with severe abdominal pain and anorexia for six months. A heterogeneously enhancing solid cystic mass was detected in the pancreatic head on contrast enhanced computed tomography...
February 4, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28266288/parathyroid-adenomas-in-adults-and-adolescents-critical-appraisal-and-surgical-strategy-in-18-cases
#11
Mihai Radu Diaconescu, Ioan Costea, Mihai Glod, Radu Terinte, Smaranda Diaconescu
Background: Our study underline scarcity of isolated case reports or small case series of parathyroid adenoma (PA) published in autochthonous medical literature,their variable clinical expression among the "historic" varieties but also the diagnostic difficulties and delays of diagnosis as well consecration of surgery as the golden therapeutic standard of this disorder. PATIENTS AND METHOD: Demographic, clinical presentations, laboratory and imaging data, operative findings and procedures together with pathology account and outcome from the case reports of 18 patients with documented PHP were retrospectively analyzed...
January 2017: Chirurgia
https://www.readbyqxmd.com/read/28261978/the-cellularity-yield-of-three-different-22-gauge-endoscopic-ultrasound-fine-needle-aspiration-needles
#12
Mohamed O Othman, Mohamed M Abdelfatah, Osvaldo Padilla, Maha Hussinat, Sherif Elhanafi, Mohamed Eloliby, Alireza Torabi, Nawar Hakim, Darius A Boman
BACKGROUND: Endoscopic ultrasound (EUS) fine needle aspiration (FNA) is an integral part in the diagnosis of pancreatic, intestinal and extra-intestinal masses or lesions. There is no clear data on the superiority of the core biopsy needle over standard 22-gauge needles. The aim of this study is to prospectively compare the cellularity yield of three commonly used 22-gauge FNA needles available in the US market. METHODS: This is a prospective, randomized study comparing the cellularity yield of three commercially available EUS needles (two standard FNA needles and core biopsy needle)...
March 6, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28260012/novel-quantitative-analysis-of-the-s100p-protein-combined-with-endoscopic-ultrasound-guided-fine-needle-aspiration-cytology-in-the-diagnosis-of-pancreatic-adenocarcinoma
#13
Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma
Specimens obtained with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) are often tiny and fragmented leading to an inconclusive and doubtful diagnosis. To overcome the limitations of EUS-FNA in the cytological diagnosis of pancreatic adenocarcinoma (PCA), we evaluated whether quantification of the S100P protein combined with EUS-FNA reliably discriminated between PCA and benign pancreatic lesions (BPL). A high sensitivity sandwich ELISA for S100P protein was developed to aid in the detection of PCA in small samples obtained using EUS-FNA...
February 21, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28250896/endoscopy-guided-ablation-of-pancreatic-lesions-technical-possibilities-and-clinical-outlook
#14
REVIEW
Marianna Signoretti, Roberto Valente, Alessandro Repici, Gianfranco Delle Fave, Gabriele Capurso, Silvia Carrara
Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP)-guided ablation procedures are emerging as a minimally invasive therapeutic alternative to radiological and surgical treatments for locally advanced pancreatic cancer (LAPC), pancreatic neuroendocrine tumours (PNETs), and pancreatic cystic lesions (PCLs). The advantages of treatment under endoscopic control are the real-time imaging guidance and the possibility to reach a deep target like the pancreas. Currently, radiofrequency probes specifically designed for ERCP or EUS ablation are available as well as hybrid cryotherm probe combining radiofrequency with cryotechnology...
February 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28246589/difficult-endoscopic-diagnosis-of-a-pancreatic-plasmacytoma-case-report-and-review-of-literature
#15
Nicolas Williet, Radwan Kassir, Muriel Cuilleron, Olivier Dumas, Leslie Rinaldi, Karine Augeul-Meunier, Michèle Cottier, Xavier Roblin, Jean-Marc Phelip
A 71-year-old man, with history of plasmacytoma in relapse since one year, was hospitalized for a initial presentation of acute pancreatitis and hepatitis. Although there was a heterogeneous infiltration around the pancreas head, the diagnosis of an extramedullary localization of his plasmacytoma was not made until later. This delayed diagnosis was due to the lack of specific radiologic features and the lack of dilatation of biliary ducts at the admission. A diagnosis was made with a simple ultrasound guided paracentesis of the low abundance ascites after a transjugular hepatic biopsy, an endoscopic ultrasound-guided fine needle aspiration of the pancreatic mass, and a failed attempt of biliary drainage through endoscopic retrograde cholangiopancreatography...
February 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28243612/trigemino-autonomic-headache-and-horner-syndrome-as-a-first-sign-of-granulomatous-hypophysitis
#16
Jeremias Motte, Ilonka Kreitschmann-Andermahr, Anna Lena Fisse, Christian Börnke, Christoph Schroeder, Kalliopi Pitarokoili, Oliver Müller, Carsten Lukas, Johannes van de Nes, Rolf Buslei, Ralf Gold, Ilya Ayzenberg
OBJECTIVE: To report a rare case of incipient granulomatous hypophysitis presenting by atypical trigemino-autonomic cephalalgia (TAC) and Horner syndrome. METHODS: The patient was investigated with repeated brain MRI, CSF examination, thoracic CT, Doppler and duplex ultrasound of the cerebral arteries, and extensive serologic screening for endocrine and autoimmune markers. Written informed consent was obtained from the patient for access to clinical files for research purposes and for publication...
May 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28243046/single-dose-intra-procedural-ceftriaxone-during-endoscopic-ultrasound-fine-needle-aspiration-of-pancreatic-cysts-is-safe-and-effective-results-from-a-single-tertiary-center
#17
Amir Klein, Rose Qi, Shyam Nagubandi, Eric Lee, Vu Kwan
BACKGROUND: Endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) is universally used for the investigation and diagnosis of pancreatic cystic lesions (PCL). Infectious complications following EUS-FNA of PCL are rare. Antibiotic prophylaxis to reduce the risk of infection is recommended; however, there is no consensus on the optimal regimen or route of administration. Potential advantages of a single-dose intravenous (IV) antibiotic over a prolonged oral regimen include simplicity, guaranteed delivery and fewer antibiotic related adverse events, but there are only limited data to support this...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28243045/prognostic-significance-of-differentiating-necrosis-from-fluid-collection-on-endoscopic-ultrasound-in-patients-with-presumed-isolated-extrapancreatic-necrosis
#18
Surinder S Rana, Puneet Chhabra, Ravi Sharma, Vishal Sharma, Rajesh Gupta, Deepak K Bhasin
BACKGROUND: Extrapancreatic necrosis is diagnosed on computed tomography (CT) as extrapancreatic changes that are more than fat stranding; both fluid collections and necrosis would have a similar appearance. The aim of this study was to determine the prognostic significance of differentiating peripancreatic necrosis from fluid collection on endoscopic ultrasound (EUS) in patients with presumed isolated extrapancreatic necrosis. METHODS: We carried out a retrospective analysis of prospectively collected data from 36 patients (25 males; age range 19-65 years) with acute pancreatitis (AP) and isolated extrapancreatic necrosis...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28240038/atraumatic-splenic-rupture-as-a-complication-of-acute-exacerbation-of-chronic-pancreatitis-an-unusual-disease
#19
Elena Moya Sánchez, Antonio Medina Benítez
We report the case of a patient with acute exacerbation of chronic pancreatitis and he suffered an atraumatic splenic rupture. Splenic rupture not associated with trauma is a rare entity that can occurs in normal spleen (spontaneous) or damaged spleen (pathological). This entity may be associated with local inflammatory processes, such as pancreatitis. Ultrasound is a non-invasive technique which is used in unstable patients. CT is useful for making a diagnosis of extension in patients with hemodynamic stability...
February 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28238770/association-between-screen-detected-gallstone-disease-and-cancer-in-a-cohort-study
#20
Daniel Mønsted Shabanzadeh, Lars Tue Sørensen, Torben Jørgensen
BACKGROUND & AIMS: Knowledge of temporal associations between screen-detected gallstone disease and specific cancers is limited. The objective of this study was to determine if screen-detected gallstones or cholecystectomy is associated with occurrence of gastrointestinal and non-gastrointestinal cancers. METHODS: We performed a cohort study of 3 randomly selected groups from the general population of Copenhagen. Participants (n=5928) were examined from 1982 through 1992 and underwent abdominal ultrasound examination to detect gallstone disease, but were not informed of their gallstone status...
February 23, 2017: Gastroenterology
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