Jorge Arturo Sepúlveda-García, David Hernán Martínez-Puente, Raquel Guadalupe Ballesteros-Elizondo, Humberto Rodríguez-Rocha, Aracely García-García, Adolfo Soto-Domínguez, Odila Saucedo-Cárdenas, José Félix Vilchez-Cavazos, Roberto Montes de Oca-Luna, María de Jesús Loera-Arias
Anterior cruciate ligament injuries are frequent afflictions related to sports or physical trauma. Autograft reconstruction strategies cause secondary injury to the patient. One alternative, supported by clinical evidence, is porcine xenografts. For clinical use, xenografts must be conditioned to avoid immune rejection. The most widely accepted procedure is tissue decellularization. We analyzed three decellularization strategies: the application of the anionic detergent sodium dodecyl sulfate (SDS), sonication, and freezing and thawing cycles...
May 10, 2024: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission