keyword
https://read.qxmd.com/read/38528064/visualization-of-bone-formation-in-sheep-s-middle-ear-by-using-fluorochrome-sequential-labelling-fsl
#21
JOURNAL ARTICLE
Max Kemper, Anne Kluge, Michael Ney, Thomas Beleites, Ines Zeidler-Rentzsch, Christiane Keil, Thomas Zahnert, Marcus Neudert
One factor for the lacking integration of the middle ear stapes footplate prosthesis or the missing healing of stapes footplate fractures could be the known osteogenic inactivity. In contrast, it was recently demonstrated that titanium prostheses with an applied collagen matrix and immobilised growth factors stimulate osteoblastic activation and differentiation on the stapes footplate. Regarding those findings, the aim of this study was to evaluate the potential of bone regeneration including bone remodeling in the middle ear...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38526057/animal-exposure-model-for-mapping-crimean-congo-hemorrhagic-fever-virus-emergence-risk
#22
JOURNAL ARTICLE
Sara Baz-Flores, Débora Jiménez-Martín, Alfonso Peralbo-Moreno, Cesar Herraiz, David Cano-Terriza, Raúl Cuadrado-Matías, Ignacio García-Bocanegra, Francisco Ruiz-Fons
To estimate the determinants of spatial variation in Crimean-Congo hemorrhagic fever virus (CCHFV) transmission and to create a risk map as a preventive public health tool, we designed a survey of small domestic ruminants in Andalusia, Spain. To assess CCHFV exposure spatial distribution, we analyzed serum from 2,440 sheep and goats by using a double-antigen ELISA and modeled exposure probability with environmental predictors by using generalized linear mixed models. CCHFV antibodies detected in 84 samples confirmed low CCHFV prevalence in small domestic ruminants in the region...
April 2024: Emerging Infectious Diseases
https://read.qxmd.com/read/38525270/a-multiplex-dna-probe-based-method-for-simultaneous-identification-of-adulteration-in-meat-samples
#23
JOURNAL ARTICLE
Smriti Singh Yadav, Ramsha Tariq, Prabeen Kumar Padhy, Apoorva Saxena, Pawankumar Rai, Vikas Srivastava, Navjot Kumar, Sandeep Kumar Sharma, Smriti Priya
Meat adulteration and admixing are prevalent malpractices observed in processed and raw meat samples, where the consumption of adulterated meat has been associated with food allergies, financial losses, and consumer distrust. Meat authentication is pivotal to address these concerns. The meat authenticity can be determined through genetic, protein, and immunological markers and advanced detection methods. However, these methods often target a single species and lack the specificity to distinguish closely related species...
July 30, 2024: Food Chem (Oxf)
https://read.qxmd.com/read/38525222/the-activity-of-monocyte-derived-macrophages-after-stimulation-with-platelet-rich-and-platelet-poor-concentrates-study-on-an-ovine-model-of-insertion-of-a-tibial-implant-coated-with-silicon-doped-diamond-like-carbon
#24
JOURNAL ARTICLE
Bartłomiej Szymczak, Andrzej Junkuszew, Krzysztof Patkowski, Tomasz Szponder, Dominika Nguyen Ngoc, Beata Drzewiecka, Aleksandra Sobczyńska-Rak, Joanna Wessely-Szponder
INTRODUCTION: Macrophages are crucial immune cells that play a role in tissue repair and can exhibit pro- or anti-inflammatory behaviour based on environmental stimulation. Their functional phenotype can be affected by platelet-derived products as determined by those products' composition. When the inflammatory response caused by implantation is excessive, it can lead to rejection of the implant. Therefore, a thorough evaluation of implant haemocompatibility is necessary to minimise undesirable consequences...
March 2024: Journal of Veterinary Research
https://read.qxmd.com/read/38525027/purifying-and-balancing-selection-on-embryonic-semi-lethal-haplotypes-in-a-wild-mammal
#25
JOURNAL ARTICLE
Martin A Stoffel, Susan E Johnston, Jill G Pilkington, Josephine M Pemberton
Embryonic lethal mutations are arguably the earliest and most severe manifestation of inbreeding depression, but their impact on wild populations is not well understood. Here, we combined genomic, fitness, and life-history data from 5,925 wild Soay sheep sampled over nearly three decades to explore the impact of embryonic lethal mutations and their evolutionary dynamics. We searched for haplotypes that in their homozygous state are unusually rare in the offspring of known carrier parents and found three putatively semi-lethal haplotypes with 27%-46% fewer homozygous offspring than expected...
April 2024: Evolution Letters
https://read.qxmd.com/read/38524868/the-potential-of-sheep-in-preclinical-models-for-bone-infection-research-a-systematic-review
#26
REVIEW
Michael L C Beagan, Chris H Dreyer, Louise K Jensen, Henrik E Jensen, Thomas E Andersen, Soeren Overgaard, Ming Ding
BACKGROUND: Reliable animal models are critical for preclinical research and should closely mimic the disease. With respect to route of infection, pathogenic agent, disease progression, clinical signs, and histopathological changes. Sheep have similar bone micro- and macrostructure as well as comparable biomechanical characteristics to humans. Their use in bone research is established, however their use in bone infection research is limited. This systematic review will summarise the key features of the available bone infection models using sheep, providing a reference for further development, validation, and application...
March 2024: Journal of Orthopaedic Translation
https://read.qxmd.com/read/38524778/germany-s-first-total-diet-study-occurrence-of-non-dioxin-like-polychlorinated-biphenyls-and-polybrominated-diphenyl-ethers-in-foods
#27
JOURNAL ARTICLE
Mandy Stadion, Katrin Blume, Christin Hackethal, Anja Lüth, David M Schumacher, Oliver Lindtner, Irmela Sarvan
The occurrence of persistent organic pollutants like polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in food represents a public health concern. The BfR MEAL Study was initiated to generate a comprehensive data base of occurrence data for chemicals in the most consumed foods in Germany. Non-dioxin-like PCBs (NDL-PCBs) and PBDEs were analysed in 300 foods, purchased and prepared representatively for the eating behaviour of the population in Germany. Highest levels of NDL-PCBs and PBDEs were detected in spiny dogfish, cod liver, herring, and eel...
June 30, 2024: Food chemistry: X
https://read.qxmd.com/read/38523690/absence-of-tuberculosis-causing-mycobacteria-from-slaughtered-livestock-tissues-and-environmental-samples-gauteng-province-south-africa
#28
JOURNAL ARTICLE
Vuyokazi Mareledwane, Abiodun A Adesiyun, Tiny M Hlokwe
Mycobacterium tuberculosis complex (MTBC) is a group of bacteria responsible for causing tuberculosis in animals and humans. In South Africa (S.A), slaughterhouses are registered by the government and closely inspected and audited for hygienic slaughter practices. Meat inspection to detect lesions has been used for passive surveillance, monitoring, and diagnosis of the disease status. Information on the current status of bovine tuberculosis (bTB) in livestock in the country is limited. Hence, we investigated the occurrence of Mycobacterium spp...
2024: International Journal of Microbiology
https://read.qxmd.com/read/38523527/structural-and-sequence-analysis-of-the-rpo30-gene-of-sheeppox-and-goatpox-viruses-from-india
#29
JOURNAL ARTICLE
Gundallahalli Bayyappa Manjunatha Reddy, Krishnappa Sumana, Revanaiah Yogisharadhya, Hosakote Venkatappa Mohan, Vijaykumar Kolar Lavanya, Basavarajappa Harlipura Chethankumar, Nayakwadi Shivasharanappa, Mani Saminathan, Sajjanar Basavaraj, Kuldeep Dhama, Shivachandra Bhadravati Sathish
Sheeppox and goatpox are transboundary viral diseases of sheep and goats that cause significant economic losses to small and marginal farmers worldwide, including India. Members of the genus Capripoxvirus (CaPV), namely Sheeppox virus (SPPV), Goatpox virus (GTPV), and Lumpy skin disease virus (LSDV), are antigenically similar, and species differentiation can only be accomplished using molecular approaches. The present study aimed to understand the molecular epidemiology and host specificity of SPPV and GTPV circulating in India through sequencing and structural analysis of the RNA polymerase subunit-30 kDa ( RPO30 ) gene...
December 2024: Veterinary Quarterly
https://read.qxmd.com/read/38522780/validation-of-the-natural-sedimentation-technique-in-the-diagnosis-of-chronic-fasciolosis
#30
JOURNAL ARTICLE
Juan Rojas-Moncada, Téofilo Torrel-Pajares, Luis Vargas-Rocha
There are various diagnostic techniques available for chronic fasciolosis in ruminants. However, many of them exhibit low specificity and sensitivity, making them impractical for field use and in low-resource laboratories. The present study evaluates the usefulness of the Natural Sedimentation technique in diagnosing chronic fasciolosis in three domestic species conducted at the Laboratorio de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinas, Universidad Nacional de Cajamarca. Fecal samples were collected from n = 323 cattle, n = 362 sheep, and n = 231 swine for Fasciola hepatica fecal egg counts...
March 22, 2024: Parasitology International
https://read.qxmd.com/read/38522587/pharmacokinetic-evaluation-of-a-single-chain-antibody-fragment-against-scorpion-toxins-in-sheep
#31
JOURNAL ARTICLE
Roberto Olivares Hernández, Lidia Riaño Umbarila, Baltazar Becerril, Alejandro Alagón Cano, Hilda Vazquez Lopez
A key aspect during the development of antivenoms is the evaluation of the efficiency and security of the therapeutic molecules. In this work, we report the pharmacokinetic analysis of a neutralizing single chain antibody fragment named LR (scFv LR) where three sheep were used as a large animal model. The animals were injected through i.v. route with 2 mg of scFv LR. Blood samples were drawn every minute within the first 15 min, the sampling continues at 20, 25, 30, 45, 60, 90, 120 min, subsequently at one-hour intervals, 3, 4, 5, 6 h, two more samples at 9 and 12 h and, two more samples at 24 and 48 hours and finally at one-day intervals during 4 days...
March 22, 2024: Toxicon: Official Journal of the International Society on Toxinology
https://read.qxmd.com/read/38520755/moniezia-benedeni-infection-increases-ige-cells-in-sheep-ovis-aries-small-intestine
#32
JOURNAL ARTICLE
Jing Pan, Wan-Ling Yao, Li-Ping Liu, Bao-Shan Wang, Wen-Zhu Chai, Zhen Huang, Xi-Ping Fan, Wan-Hong He, Wen-Hui Wang, Wang-Dong Zhang
The concentration of immunoglobulin (Ig) E is the lowest among serum Igs, but it can induces type I hypersensitivity and plays an important role in anti-parasitic infection. The present study aimed to explore the residence characteristics of IgE+ cells in the sheep small intestine and the impact of Moniezia benedeni infection on them. The recombinant plasmids pET-28a-IgE were constructed and induced and expressed in Escherichia coli. BL21 (DE3). The rabbit anti-sheep IgE polyclonal antibody was prepared using the obtained recombinant protein as antigen...
March 12, 2024: Veterinary Parasitology
https://read.qxmd.com/read/38519863/orbital-shape-in-goat-and-sheep-symmetric-analysis
#33
JOURNAL ARTICLE
İftar Gürbüz, Yasin Demiraslan, İsmail Demircioğlu, Funda Aksünger Karaavci, Özcan Özgel
The aim of this study is to evaluate orbital symmetry in goat and sheep skulls. For this purpose, a total of 83 skulls, including 50 sheep and 33 goat skulls, were used in the study. Geometric morphometry method was applied. For symmetric analysis, one side of each orbit was photographed twice and mirror images were created. There were 36 landmards marked to determine the outer limit of the orbita. As a result of the study, asymmetric components (fluctuating asymmetry and directional asymmetry) for shape were statistically significant in both goats and sheep (p < 0...
May 2024: Anatomia, Histologia, Embryologia
https://read.qxmd.com/read/38518953/german-coasts-harbor-non-o1-non-o139-vibrio-cholerae-with-clinical-virulence-gene-profiles
#34
JOURNAL ARTICLE
Quantao Zhang, Thomas Alter, Eckhard Strauch, Inga Eichhorn, Maria Borowiak, Carlus Deneke, Susanne Fleischmann
Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections in human. This ability is associated with various virulence factors. The presence of NOVC in German North Sea and Baltic Sea was observed in previous studies. However, data on virulence characteristics are still scarce. Therefore, this work aimed to investigating the virulence potential of NOVC isolated in these two regions. In total, 31 NOVC strains were collected and subjected to whole genome sequencing...
March 20, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38518442/modulation-of-autophagy-affected-tumorigenesis-induced-by-the-envelope-glycoprotein-of-jsrv
#35
JOURNAL ARTICLE
Liang Zhang, Hui Yang, Xujie Duan, Huiping Li, Siriguleng Xu, Hui Chen, Jinlin Wang, Yu Wang, Shuying Liu
Ovine pulmonary adenocarcinoma (OPA), caused by the jaagsiekte sheep retrovirus (JSRV), is a chronic, progressive, and contagious lung tumor that seriously affects sheep production. It also represents a valuable animal model for several human lung adenocarcinomas. However, little is known about the role of autophagy in OPA tumorigenesis. Here, Western blotting combined with transmission electron microscopy examination and Cyto-ID dye staining was employed for evaluation of changes of autophagic levels. The results of the present study showed that expression of the autophagy marker proteins Beclin-1 and LC3 was decreased in OPA lung tissues, as well as in cells overexpressing the envelope glycoprotein of JSRV (JSRV Env)...
March 13, 2024: Virology
https://read.qxmd.com/read/38514717/epidemiology-and-field-efficacy-of-anthelmintic-drugs-associated-with-gastrointestinal-nematodes-of-sheep-in-nejo-district-oromia-ethiopia
#36
JOURNAL ARTICLE
Latera Solomon, Geremew Haile, Nejash A Ahmed, Debela Abdeta, Workineh Galalcha, Yacob Hailu
Gastrointestinal nematodes (GINs) are major constraints to health and productivity of small ruminants. Methods of their control relies mainly on anthelmintic drugs; however, the indiscriminate use of these drugs could lead to the development of anthelmintic resistance (AR). This study aimed to investigate the epidemiology of GINs infection, and field evaluation of anthelmintic efficacy in sheep. The epidemiological data were collected using a cross-sectional study design while a farm-based field study design was employed for the evaluation of anthelminthic efficacy...
March 21, 2024: Scientific Reports
https://read.qxmd.com/read/38513828/hepatogenic-photosensitization-in-lambs-supplemented-with-different-levels-of-extruded-urea-in-brachiaria-spp-pastures-in-the-brazilian-cerrado-case-report
#37
JOURNAL ARTICLE
Francisca Fernanda da Silva Roberto, Gelson Dos Santos Difante, Luís Carlos Vinhas Ítavo, Camila Celeste Brandão Ferreira Ítavo, Jéssica Gomes Rodrigues, Marislayne de Gusmão Pereira, Marcelo Augusto de Araújo, Diego Gomes Freire Guidolin, Hitalo Rodrigues da Silva, Neila Lidiany Ribeiro
The aim was to report cases and risk factors for hepatogenous photosensitization in lambs kept on Brachiaria spp. pastures and supplemented with levels of extruded urea (EU). The herd consisted of 69 Texel crossbred lambs with known parentage (fathers and mothers adapted to the consumption of forage of the genus Brachiaria), randomly divided into 5 groups and distributed in individual paddocks for each group. The animals were supplemented with increasing levels of EU (Amireia® 200S): 0, 6, 12, 18, and 24 g of EU per 100 kg-1 of body weight (BW)...
March 19, 2024: Toxicon: Official Journal of the International Society on Toxinology
https://read.qxmd.com/read/38513446/association-of-%C3%AE-globin-polymorphisms-and-tolerance-to-haemonchosis-in-ewes-and-lambs-of-different-sheep-breeds
#38
JOURNAL ARTICLE
Rafaela Tami Ikeda Kapritchkoff, Cintia Hiromi Okino, Simone Cristina Méo Niciura, Hornblenda Joaquina Silva Bello, Renata Silva Matos, Glaucia Roberta Melito, Flavia Aline Bressani, Sérgio Novita Esteves, Ana Carolina de Souza Chagas
Gastrointestinal nematodes (GIN), especially Haemonchus contortus, represent a significant challenge for sheep production. Given the global concern about GIN anthelmintic resistance, alternative control methods able to reduce the dependence on these drugs are highly advisable. Since previous studies have shown that sheep carrying the Hb-A allele of β-globin are more resistant to H. contortus, this study aimed to investigate the relationship between the different haplotypes (Hb-AA, Hb-AB and Hb-BB) and phenotypes in Santa Inês (SI), Texel (TX) and White Dorper (DO) breeds infected with H...
March 7, 2024: Veterinary Parasitology
https://read.qxmd.com/read/38513379/trilobolide-6-o-isobutyrate-from-sphagneticola-trilobata-acts-by-inducing-oxidative-stress-metabolic-changes-and-apoptosis-like-processes-by-caspase-3-7-activation-of-human-lung-cancer-cell-lines
#39
JOURNAL ARTICLE
Virginia Marcia Concato-Lopes, Manoela Daiele Gonçalves-Lens, Fernanda Tomiotto-Pellissier, Mariana Barbosa Detoni, Ellen Mayara Souza Cruz, Bruna Taciane da Silva Bortoleti, Amanda Cristina Machado Carloto, Ana Carolina Jacob Rodrigues, Taylon Felipe Silva, Elaine da Silva Siqueira, Ricardo Luís Nascimento de Matos, Ian Lucas Alves Cardoso, Ivete Conchon-Costa, Danielle Lazarin-Bidóia, Nilton Syogo Arakawa, Robert F H Dekker, Mário Sérgio Mantovani, Wander Rogério Pavanelli
BACKGROUND: Lung cancer, a chronic and heterogeneous disease, is the leading cause of cancer-related death on a global scale. Presently, despite a variety of available treatments, their effectiveness is limited, often resulting in considerable toxicity and adverse effects. Additionally, the development of chemoresistance in cancer cells poses a challenge. Trilobolide-6-O-isobutyrate (TBB), a natural sesquiterpene lactone extracted from Sphagneticola trilobata, has exhibited antitumor effects...
March 13, 2024: Phytomedicine
https://read.qxmd.com/read/38512703/empty-vein-ablation-eva-technique-an-in-vivo-animal-model-to-assess-the-effects-of-sclerosing-agent-concentration-and-wall-contact-time-on-intima-and-media-tunicae-structure
#40
JOURNAL ARTICLE
Mario Salerno, Daniele Bissacco, Yung-Wei Chi, Sryram Narayanan, Alessandro Addis, Claudia Dellavia, Elena Canciani, Paolo C Righini, Giovanni Nano, Sergio Gianesini
BACKGROUND: Sclerotherapy is a cornerstone of the treatment of chronic venous disease, despite some technical aspects (e.g., sclerosant liquid agent concentration [SLAC] and contact time between sclerosant agent and vein wall [ctSA/VW]) to maximize outcomes remain an unsolved problem and a source of debate. An innovative three-balloon catheter has been developed to allow sclerotherapy in empty vein conditions (Empty Vein Ablation technique, EVA), revolutionizing the definition of SLAC and ctSA/VW...
March 21, 2024: International Angiology: a Journal of the International Union of Angiology
keyword
keyword
18957
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.