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https://www.readbyqxmd.com/read/29777962/field-evaluation-of-anticoccidial-efficacy-a-novel-approach-demonstrates-reduced-efficacy-of-toltrazuril-against-ovine-eimeria-spp-in-norway
#1
Ane Odden, Matthew J Denwood, Snorre Stuen, Lucy J Robertson, Antonio Ruiz, Inger Sofie Hamnes, Lisbeth Hektoen, Heidi L Enemark
Ovine Eimeria spp. infections cause reduced welfare, increased mortality, and substantial economic losses, and anticoccidials are crucial for their control. Recent reports of toltrazuril resistance in pigs, and anecdotal reports of reduced anticoccidial efficacy in lambs, necessitate evaluation of anticoccidial efficacy. Due to the substantial lifecycle differences between nematodes and coccidia, current WAAVP methods for assessing anthelmintic efficacy are not suitable for such evaluations. Faecal samples were collected from 8 pairs of twin lambs from 36 Norwegian sheep farms 6-8 days after turnout...
May 16, 2018: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/29777850/a-novel-cardiovascular-prosthesis-made-from-woven-ultra-high-molecular-weight-polyethylene-fibers-proof-of-concept-in-a-sheep-model
#2
Amir Basir, Mylène Loncq de Jong, Aryan Vink, Gerard Pasterkamp, Paul Gründeman, Frans Moll, Joost van Herwaarden
BACKGROUND: A patch, made of woven ultra-high molecular weight polyethylene (UHMWPE) fibers is thin, strong, and flexible, and may be attractive for use in cardiovascular prostheses. This study assessed the hemocompatibility of this patch in a sheep model. METHODS: The UHMWPE patches were sutured in the right carotid artery and jugular vein in 12 adult sheep, and in the same animal, expanded polytetrafluoroethylene (ePTFE) patches were sutured as control patches in the left carotid artery and jugular vein...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777365/effects-of-replacing-rye-grass-lolium-spp-hay-by-banana-musa-acuminata-l-by-products-on-feed-intake-growth-and-feed-conversion-rate-of-canary-hair-sheep-breed-pelibuey-lambs
#3
M Barbera, J R Jaber, S Ahmed-Salek, A Ravelo-Garcia, E Rodríguez-Ponce, L Rey, M R Ventura
The objective of this study was to evaluate the effects of replacing rye-grass (Lolium spp.) hay with banana (Musa acuminata L.) by-products on feed intake, average daily gain (ADG), and feed conversion rate (FCR) in Pelibuey (hair sheep breed) lambs. The lambs (n = 22; initial BW = 14.8 ± 2.5 kg) were individually housed and fed on two different types of diet for 58 days: the first group (experimental diet) received as forage a mixture of fresh banana by-products composed of leaves and pseudostem...
May 19, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29776647/-effect-of-green-alga-ulva-lactuca-polysaccharides-supplementation-on-blood-pressure-and-on-atherogenic-risk-factors-in-rats-fed-a-high-fat-diet
#4
Z I Tair, F Bensalah, F Boukortt
AIM OF THE STUDY: To highlight the benefits of green alga Ulva lactuca polysaccharides supplementation on blood pressure and atherogenic risk factors in rats fed a high fat diet. METHODS: Wistar male rats were fed a high fat diet (30% sheep fat) for 3 months. At an average body weight (BW) of 360g, the rats (n=18) were divided into 3 groups and consumed, for 28 days, either a high fat diet (HFD) or a high fat diet enriched with 1% of whole green algae (WGA) powder or with 1% of its polysaccharides (PLS)...
May 15, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29776560/large-animal-model-of-acute-right-ventricular-failure-with-functional-tricuspid-regurgitation
#5
Marcin Malinowski, Alistair G Proudfoot, Lenora Eberhart, Hans Schubert, Jeremy Wodarek, David Langholz, Manuel K Rausch, Tomasz A Timek
BACKGROUND: Functional tricuspid regurgitation (FTR) commonly arises secondary to conditions affecting the left heart and is associated with right ventricular dysfunction and tricuspid annular dilatation. We set out to establish an animal model of acute RV failure (RVF) with FTR resembling the clinical features. METHODS: Ten adult sheep had pressure sensors placed in the LV, RV, and right atrium while sonomicrometry crystals were implanted around tricuspid annulus and on the RV...
August 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29774950/morphology-and-quantification-of-sheep-pineal-glands-at-pre-pubertal-pubertal-and-post-pubertal-periods
#6
Durmuş Bolat, Aytül Kürüm, Sıla Canpolat
The pineal gland is a neuroendocrine organ associated with photoperiodic regulation in mammals. The aim of this study was to evaluate the pineal gland at the pre-pubertal, pubertal and post-pubertal periods by means of morphology and stereology. The study examined at total of 24 ovine pineal glands collected from healthy female Akkaraman breed. Thick sections (40 μm) were cut and treated with synaptophysin. Following each thick section, six consecutive sections at a thickness of 5 μm were cut. Each thin section was stained with one of the following dyes: Crossman's modified triple dye, glial fibrillary acidic protein (GFAP), melatonin marker, periodic acid-Schiff, Von Kossa and AgNOR...
May 18, 2018: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/29774586/genome-wide-association-study-reveals-novel-genes-for-the-ear-size-in-sheep-ovis-aries
#7
L Gao, S-S Xu, J-Q Yang, M Shen, M-H Li
Variations in ear size can be observed in livestock such as sheep; however, the genetic basis of variable ear size in sheep is still poorly understood. To investigate causative genes associated with ear size in sheep, a genome-wide association study was performed in 115 adult Duolang sheep with different-sized floppy ears using the Ovine Infinium HD BeadChip. We found 38 significant SNPs at the genome-wide or chromosome-wise 5% significance level after Bonferroni correction. The most significant association (P = 1...
May 18, 2018: Animal Genetics
https://www.readbyqxmd.com/read/29774298/cystic-echinococcosis-in-marketed-offal-of-sheep-in-basrah-iraq-abattoir-based-survey-and-a-probabilistic-model-estimation-of-the-direct-economic-losses-due-to-hydatid-cyst
#8
Mohanad F Abdulhameed, Ihab Habib, Suzan A Al-Azizz, Ian Robertson
Cystic echinococcosis (CE) is a highly endemic parasitic zoonosis in Iraq with substantial impacts on livestock productivity and human health. The objectives of this study were to study the abattoir-based occurrence of CE in marketed offal of sheep in Basrah province, Iraq, and to estimate, using a probabilistic modelling approach, the direct economic losses due to hydatid cysts. Based on detailed visual meat inspection, results from an active abattoir survey in this study revealed detection of hydatid cysts in 7...
February 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29773127/taeniid-metacestodes-in-rangeland-goats-in-australia
#9
D J Jenkins, B Cowled, V Brookes
Data on several infections of sheep and goats, including parasite infections, are routinely collected during inspection of harvested rangeland goats after slaughter. This is an important role of the Australian National Sheep Health Monitoring Program (NSHMP). Our study investigated the presence of metacestodes of Taenia hydatigena, T. ovis and Echinococcus granulosus in slaughtered goats from Queensland, New South Wales and Western Australia. During the period of the study (2007-2013) 374,580 goats were slaughtered and inspected by trained abattoir meat inspectors as part of the NSHMP...
May 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29772884/validation-of-a-spatial-liver-fluke-model-under-field-conditions-in-ireland
#10
Amalia Naranjo Lucena, María Pía Munita Corbalán, Ana María Martínez-Ibeas, Guy McGrath, Riona Sayers, Grace Mulcahy, Annetta Zintl
Fasciola hepatica is the causative agent of fasciolosis, a global disease of a wide range of mammals, particularly sheep and cattle. Liver fluke infection causes annual losses estimated at around €2.5 billion to livestock and food industries worldwide. Various models have been developed to define risk factors and predict exposure to this liver fluke in ruminants in European countries, most of them based exclusively on data from dairy herds. The aim of this study was to validate a published theoretical baseline risk map of liver fluke exposure and cluster maps in Ireland, by including further explanatory variables and additional herd types that are spatially more widespread...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29772327/creation-of-abdominal-aortic-aneurysms-in-sheep-by-extrapolation-of-rodent-models-is-it-feasible
#11
Peter Verbrugghe, Jelle Verhoeven, Marnick Clijsters, Dominique Vervoort, Walter Coudyzer, Eric Verbeken, Bart Meuris, Paul Herijgers
BACKGROUND: Aortic abdominal aneurysms are a potentially deathly disease, needing surgical or endovascular treatment. To evaluate potentially new diagnostic tools and treatments a large animal model, which not only resembles the morphological characteristics but also the pathophysiological background, would be useful. MATERIALS AND METHODS: Rodent animal aneurysm models were extrapolated to sheep. Four groups were created: intraluminal infusion with an elastase-collagenase solution (n=4), infusion with elastase-collagenase solution combined with proximal stenosis (n=7), aortic xenograft (n=3), and elastase-collagenase treated xenograft (n=4)...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29772265/administration-of-low-dose-triclosan-to-pregnant-ewes-results-in-placental-uptake-and-reduced-estradiol-sulfotransferase-activity-in-fetal-liver-and-placenta
#12
Erin N Jackson, Laura Rowland-Faux, Margaret O James, Charles E Wood
Sulfonation is a major pathway of estrogen biotransformation with a role in regulating estrogen homeostasis in humans and sheep. Previous in vitro studies found that triclosan is an especially potent competitive inhibitor of ovine placental estrogen sulfotransferase, with Kic of <0.1 nM. As the placenta is the main organ responsible for estrogen synthesis in pregnancy in both women and sheep, and the liver is another site of estrogen biotransformation, this study examined the effects of triclosan exposure of pregnant ewes on placental and hepatic sulfotransferase activity...
May 14, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29772054/oxycodone-pharmacokinetics-and-fetal-exposure-after-intravenous-or-epidural-administration-to-the-ewe
#13
Mari Kinnunen, Hannu Kokki, Heidi Hautajärvi, Heikki Huhta, Veli-Pekka Ranta, Juha Räsänen, Hanna-Marja Voipio, Merja Kokki
INTRODUCTION: There are limited data of oxycodone pharmacokinetics during pregnancy and on fetal exposure after maternal administration. The present study describes the pharmacokinetics of intravenous oxycodone in pregnant sheep and fetal exposure after intravenous and epidural administration. MATERIAL AND METHODS: 10 pregnant sheep received 0.1 mg·kg-1 oxycodone intravenously -bolus, and blood samples were collected up to 24 hours. Seven days later, the ewes were randomized to receive 0...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29770944/analysis-of-pastoralists-perception-on-challenges-and-opportunities-for-sheep-and-goat-production-in-northern-kenya
#14
Mohamed Haji Abdilatif, Joshua Orungo Onono, Florence Kanini Mutua
Small ruminants' production contributes to livelihood of pastoral communities, but this faces myriad constraints. This study aimed at identifying challenges facing producers of small ruminants, prioritizing diseases and their control measures and documenting opportunities for improvement. Sixteen focus group discussions with livestock owners and 13 key informant interviews were done in selected areas in Mandera County, Northern Kenya, and both quantitative and qualitative data collected using a questionnaire guide...
May 16, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29770660/-genotyping-and-gene-nucleotide-polymorphism-of-epidemic-strain-of-echinococcus-granulosus-metacestode-from-humans-and-sheep-in-tianjun-region-qinghai-province
#15
Zhang Xue-Yong, Jian Ying-Na, Li Xiu-Ping, Han Xiu-Ming, Caidan Zhuo-Ma, Li Fu-Shou, Ma Li-Qing
OBJECTIVE: To understand the genotypes and nucleotide polymorphisms of Echinococcus granulosus metacestode from humans and sheep in Tianjun region, Qinghai Province. METHODS: The specific primers were designed according to the cox1 and nad1 genes of E. granulosus mitochondrial genome sequences accessed by GenBank. The primers were used to detect the cyst samples from 16 sheep and 2 humans infected with E. granulosus in Tianjun region of Qinghai Province by PCR, then the PCR amplification products were sequenced, the genotypes and nucleotide polymorphisms of the cox1 and nad1 genes were analyzed...
March 12, 2018: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29770578/effect-of-silicon-doped-calcium-phosphate-bone-grafting-materials-on-bone-regeneration-and-osteogenic-marker-expression-after-implantation-in-the-ovine-scapula
#16
Christine Knabe, Doaa Adel-Khattab, Wolf-Dietrich Hübner, Fabian Peters, Tom Knauf, Barbara Peleska, Dirk Barnewitz, Antje Genzel, Roderik Kusserow, Florian Sterzik, Michael Stiller, Christian Müller-Mai
Compared to the currently clinically available bone grafting materials for alveolar ridge augmentation, there is a great demand for bioactive bone substitutes with higher resorbability, which enhance osteogenesis at the same time. This has prompted the development of a silicon-doped rapidly resorbable calcium alkali orthophosphate (Si-CAOP) and silicon-doped β-tricalcium phosphate (Si-TCP). This study evaluated the effect of these two particulate graft materials as compared to the currently clinically used β-TCP on bone formation and osteogenic marker expression after 2 weeks, 1, 3, 6, 12, and 18 months of implantation in critical size defects in the sheep scapula...
May 16, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29768563/occurrence-of-blastocystis-spp-in-domestic-animals-in-tri%C3%A3-ngulo-mineiro-area-of-brazil
#17
Renata Gregório Franco Moura, Márcia Benedita de Oliveira-Silva, André Luiz Pedrosa, Gabriel Antônio Nogueira Nascentes, Marlene Cabrine-Santos
INTRODUCTION: Currently, there are few studies regarding Blastocystis epidemiology. This study aimed to evaluate the occurrence of Blastocystis in animals in Uberaba, Brazil. METHODS: Fecal samples were examined by parasitological methods and screened for Blastocystis by polymerase chain reaction. RESULTS: Blastocystis spp. were observed in pigs, sheep, cattle, and dogs. Blastocystis polymerase chain reaction was positive in 14/22 samples positive by parasitological methods...
March 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29767729/a-comparative-study-on-the-excretion-of-urinary-metabolites-in-goats-and-sheep-to-evaluate-spot-sampling-applied-to-protein-nutrition-trials
#18
A C S Dos Santos, S A Santos, G G P Carvalho, L D S Mariz, M S L Tosto, S C Valadares Filho, J A G Azevedo
The main objective of this study was to establish a protocol to validate urine spot samples to estimate N excretion and microbial synthesis in goat and sheep; and to study factors that affect daily creatinine and purine derivatives urinary excretion. Also a performance trial was carried out to compare goat and sheep slaughtered after different feedlot periods. Twelve Boer goats (20.6 kg±3.4 initial BW) and twelve Dorper sheep (18.4 kg±2.3 initial BW), all 4-month-old, males, were used. Eight animals (four goats and four sheep) were randomly allocated to be slaughtered at 28, 56 and 84 days in feedlot...
May 15, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29767720/functional-analyses-of-rare-genetic-variants-in-complement-component-c9-identified-in-patients-with-age-related-macular-degeneration
#19
Mariann Kremlitzka, Maartje J Geerlings, Sarah de Jong, Bjorn Bakker, Sara C Nilsson, Sascha Fauser, Carel B Hoyng, Eiko K de Jong, Anneke I den Hollander, Anna M Blom
Age-related macular degeneration (AMD) is a progressive disease of the central retina and the leading cause of irreversible vision loss in the western world. The involvement of abnormal complement activation in AMD has been suggested by association of variants in genes encoding complement proteins with disease development. A low-frequency variant (p.P167S) in the complement component C9 (C9) gene was recently shown to be highly associated with AMD, however its functional outcome remains largely unexplored. In this study, we reveal five novel rare genetic variants (p...
May 14, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29767143/okara-as-a-protein-supplement-affects-feed-intake-and-milk-composition-of-ewes-and-growth-performance-of-lambs
#20
Laura B Harthan, Debbie J R Cherney
Evaluating the feeding value of wet okara as a protein supplement for lactating ewes with twin lambs was the objective. A 4 × 4 Latin square replicated 2× (4 sheep, 4 treatments, 4 periods per square; 2 squares) was conducted to examine the influence of concentrate mix (okara or not) and type of forage (silage or hay) on ewe milk composition and growth of their lactating lambs. Treatment periods were 14 days (7 days adaptation and 7 days collection). Ewes (55 to 74.8 kg BW) were fed 1 of 4 diets: wheat middling and corn concentrate with mixed grass hay (TSH), okara and corn with mixed grass hay (OSH), soybean and wheat middlings with hay crop silage (TSS), and okara and corn with hay crop silage (OSS)...
June 2017: Animal nutrition
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