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https://www.readbyqxmd.com/read/29344947/genome-wide-population-structure-and-admixture-analysis-reveals-weak-differentiation-among-ugandan-goat-breeds
#1
R B Onzima, M R Upadhyay, R Mukiibi, E Kanis, M A M Groenen, R P M A Crooijmans
Uganda has a large population of goats, predominantly from indigenous breeds reared in diverse production systems, whose existence is threatened by crossbreeding with exotic Boer goats. Knowledge about the genetic characteristics and relationships among these Ugandan goat breeds and the potential admixture with Boer goats is still limited. Using a medium-density single nucleotide polymorphism (SNP) panel, we assessed the genetic diversity, population structure and admixture in six goat breeds in Uganda: Boer, Karamojong, Kigezi, Mubende, Small East African and Sebei...
January 17, 2018: Animal Genetics
https://www.readbyqxmd.com/read/29344801/toxoplasma-gondii-in-sympatric-domestic-and-wild-ungulates-in-the-mediterranean-ecosystem
#2
S Almería, O Cabezón, J Paniagua, D Cano-Terriza, S Jiménez-Ruiz, A Arenas-Montes, J P Dubey, I García-Bocanegra
Toxoplasma gondii is a zoonotic protozoan of worldwide distribution. The present study provides information on risk factors affecting T. gondii infection in domestic and free-ranging wild ungulates sharing habitats in Mediterranean ecosystems in Spain. Serum samples from 482 extensively reared domestic ruminants and 2351 wild ungulates were tested for T. gondii antibodies using the modified agglutination test (MAT, cut-off 1:25). Toxoplasma gondii seroprevalence was 41.2% of 194 sheep, 18.6% of 199 cattle and 5...
January 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29340871/neurotoxicity-of-prosopis-juliflora-from-natural-poisoning-to-mechanism-of-action-of-its-piperidine-alkaloids
#3
Victor Diogenes Amaral da Silva, André Mario Mendes da Silva, Juliana Helena Castro E Silva, Silvia Lima Costa
Prosopis juliflora was introduced in northeastern Brazil in the 1940s, and since then, it has been available as an alternative for animal nutrition. However, the consumption of P. juliflora as main or sole source of food causes an illness in animals known locally as "cara torta" disease. Cattle and goats experimentally intoxicated presents neurotoxic damage in the central nervous system. Histologic lesions were mainly characterized by vacuolation and loss of neurons in trigeminal motor nuclei. Furthermore, mitochondrial damage in neurons and gliosis was reported in trigeminal nuclei of intoxicated cattle...
January 16, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29339615/adsorption-performance-of-polydopamine-modified-attapulgite-granular-adsorbent-for-methylene-blue
#4
Weisheng Zheng, Hailing Wang, Zhaolian Zhu, Peng Wei
Polydopamine-modified granule organo-attapulgite adsorbent (PDA-GOAT) was facilely prepared via a dip-coating approach. The samples were characterized by scanning electron microscopy, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy. Surface area and pore size were calculated from the Brunauer-Emmett-Teller method by N2 adsorption-desorption isotherm. The adsorption behaviour of methylene blue (MB) onto PDA-GOAT was systematically investigated. The experimental data revealed that the adsorption process fitted well with the pseudo-second-order kinetics equation and the adsorption isotherm fitted better with the Langmuir model...
January 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29335029/estimating-the-proportion-of-clinically-diagnosed-infectious-and-non-infectious-animal-diseases-in-ganta-afeshum-woreda-eastern-tigray-zone-ethiopia
#5
Mebrahtu Tedla, Mebrahtu Gebreselassie
OBJECTIVE: This study was performed with the objective of identifying the proportion of emerging and endemic livestock diseases using cross sectional survey. RESULT: A total of 285 clinically diseased animals were presented to a veterinary clinic and diagnosed tentatively based on history, clinical sign, and simple laboratory diagnostics and from the study, actinomycosis (15.83%), mastitis (15%), tick infestation (10%), respiratory diseases (9.16%) and gastro intestinal parasitism (9...
January 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29334948/molecular-identification-and-investigations-of-contagious-ecthyma-orf-virus-in-small-ruminants-north-west-ethiopia
#6
Mebrahtu Tedla, Nega Berhan, Wassie Molla, Wudu Temesgen, Sefinew Alemu
BACKGROUND: Orf virus, the prototype of parapoxvirus, is the main causative agent of contagious ecthyma. Little is known about the status of the disease in Ethiopia and this study was aimed at determining its status using PCR as a confirmatory tool. METHODS: a total of 400 randomly selected sheep and goat was screened for the identification of the virus using amplification of B2L gene and transfection of mammalian cells (VERO cells). RESULTS: Out of 400 animals screened for infection of the virus, 48 animals were found positive to PCR and revealed an overall incidence of 12%...
January 15, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29332622/in-vivo-and-in-vitro-strategies-to-support-caprine-preantral-follicle-development-after-ovarian-tissue-vitrification
#7
N J Donfack, K A Alves, B G Alves, R M P Rocha, J B Bruno, L F Lima, C H Lobo, R R Santos, S F S Domingues, M Bertolini, J Smitz, A P R Rodrigues
The aim of the present study was to compare fresh and vitrified goat ovarian tissue after autotransplantation and in vitro culture. Adult goats were completely ovariectomised and each ovarian pair was sliced and distributed among six different treatment groups: fresh control, fresh transplant, fresh culture, vitrified control, vitrified transplant and vitrified culture. Follicular morphology, development, growth, density, revascularisation and hormone production were evaluated in all groups. Three antral follicles (two in the fresh transplant and one in the vitrified transplant groups) were observed on the surface of the graft 90 days after transplantation...
January 15, 2018: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/29331469/peroxisome-proliferator-activated-receptor-delta-regulates-lipid-droplet-formation-and-transport-in-goat-mammary-epithelial-cells
#8
H B Shi, C H Zhang, Z A Xu, G G Lou, J X Liu, J Luo, J J Loor
Even though recent evidence in goat mammary epithelial cells (GMEC) suggest a role of peroxisome proliferator-activated receptor delta (PPARD) in regulating lipid homeostasis, its role is not fully understood. Our hypothesis was that PPARD regulates lipid transport processes in GMEC and, thus, plays a crucial role in regulating fat formation. The PPARD was overexpressed using an adenovirus system (Ad-PPARD) with recombinant green fluorescent protein (Ad-GFP) as the control. Results revealed that overexpression of PPARD markedly upregulated the mRNA abundance of PPARD...
January 10, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29329552/correction-to-linkage-whole-genome-sequence-and-biological-data-implicate-variants-in-rab10-in-alzheimer-s-disease-resilience
#9
Perry G Ridge, Celeste M Karch, Simon Hsu, Ivan Arano, Craig C Teerlink, Mark T W Ebbert, Josue D Gonzalez Murcia, James M Farnham, Anna R Damato, Mariet Allen, Xue Wang, Oscar Harari, Victoria M Fernandez, Rita Guerreiro, Jose Bras, John Hardy, Ronald Munger, Maria Norton, Celeste Sassi, Andrew Singleton, Steven G Younkin, Dennis W Dickson, Todd E Golde, Nathan D Price, Nilüfer Ertekin-Taner, Carlos Cruchaga, Alison M Goate, Christopher Corcoran, JoAnn Tschanz, Lisa A Cannon-Albright, John S K Kauwe
The original version of this article [1] unfortunately contained a typographical error. The 'Alzheimer's Disease Neuroimaging Initiative' was erroneously included as 'Alzheimer's Disease Neuroimaging Initative' in the author list of the article.
January 12, 2018: Genome Medicine
https://www.readbyqxmd.com/read/29329099/accumulation-patterns-and-risk-assessment-of-metals-and-metalloid-in-muscle-and-offal-of-free-range-chickens-cattle-and-goat-in-benin-city-nigeria
#10
Emmanuel Temiotan Ogbomida, Shouta M M Nakayama, Nesta Bortey-Sam, Balazs Oroszlany, Isioma Tongo, Alex Ajeh Enuneku, Ogbeide Ozekeke, Martins Oshioriamhe Ainerua, Iriagbonse Priscillia Fasipe, Lawrence Ikechukwu Ezemonye, Hazuki Mizukawa, Yoshinori Ikenaka, Mayumi Ishizuka
The use of free range animals for monitoring environmental health offers opportunities to detect exposure and assess the toxicological effects of pollutants in terrestrial ecosystems. Potential human health risk of dietary intake of metals and metalloid via consumption of offal and muscle of free range chicken, cattle and goats by the urban population in Benin City was evaluated. Muscle, gizzard, liver and kidney samples were analyzed for Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, and Pb concentrations using inductively coupled plasma mass spectrometer (ICP-MS) while Hg was determined using Hg analyzer...
January 9, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29329074/goat-tendon-collagen-human-fibrin-hydrogel-for-comprehensive-parametric-evaluation-of-huvec-microtissue-based-angiogenesis
#11
Rajan Narayan, Tarun Agarwal, Debasish Mishra, Tapas Kumar Maiti, Sujata Mohanty
The cell and extracellular matrix (ECM) interactions play a very important role during angiogenesis. Remodeling of the extracellular matrix along with pro-angiogenic/anti-angiogenic factors, and matrix-degrading proteases, accounts for endothelial cell growth, migration, and tube formation. However, for studying angiogenesis, only limited and expensive biomaterials are available. Despite being biocompatible, inexpensive, and easy availability; the potential of goat tendon collagen (GTC) has never been explored for vascular tissue engineering applications...
January 2, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29325417/rhubarb-supplementation-promotes-intestinal-mucosal-innate-immune-homeostasis-through-modulating-intestinal-epithelial-microbiota-in-goat-kids
#12
Jinzhen Jiao, Jian Wu, Min Wang, Chuanshe Zhou, Rong-Zhen Zhong, Zhi-Liang Tan
The abuse and misuse of antibiotics in livestock production pose a potential health risk globally. Rhubarb can serve as a potential alternative to antibiotics, and several studies have looked into its anti-cancer, anti-tumor and anti-inflammatory properties. The aim of this study was to test the effects of rhubarb supplementation to the diet of young ruminants on innate immune function and epithelial microbiota in the small intestine. Goat kids were fed with a control diet supplemented with or without rhubarb (1...
January 11, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29324350/formation-of-phosphatidylethanol-from-endogenous-phosphatidylcholines-in-animal-tissues-from-pig-calf-and-goat
#13
Marc Luginbühl, Sytske Willem, Stefan Schürch, Wolfgang Weinmann
In the presence of alcohol, phosphatidylcholine (PC) is transformed to the direct alcohol biomarker phosphatidylethanol (PEth). This reaction is catalyzed by the enzyme phospholipase D (PLD) and dependent on substrate availability. As recent methods have solely focused on the determination of PEth, information about the PC composition was generally missing. To address this issue and monitor PC (16:0/18:1 and 16:0/18:2) and PEth (16:0/18:1 and 16:0/18:2) simultaneously, a reversed phase LC-MS/MS method based on a C8 core-shell column, coupled to a Sciex 5500 QTrap instrument was developed...
December 24, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29324088/validation-of-a-rapid-lateral-flow-method-for-the-detection-of-cows-milk-in-water-buffalo-sheep-or-goat-milk
#14
Patricia Galan-Malo, Isabel Mendiara, Pedro Razquin, Luis Mata
For many years the adulteration of milk from sheep, goats or water buffalos with cows' milk has been a widespread practice due to the higher cost of milk from those other species. Because of this, great concern has been shown by many Protected Designation of Origin councils that have to assure the quality and genuineness of the cheese produced by their associates. Therefore, the whole production chain needs analytical tools that allow the control of potential adulteration. Rapid methods to be used in the field are scarce and have not been validated according to international guidelines...
January 11, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29323924/akt-serine-threonine-kinase-1-regulates-de-novo-fatty-acid-synthesis-through-mtor-srebp1-axis-in-dairy-goat-mammary-epithelial-cells
#15
Tianying Zhang, Jiangtao Huang, Yongqing Yi, Xueying Zhang, Juan J Loor, Yanhong Cao, Huaiping Shi, Jun Luo
Akt serine/threonine kinase acts as a central mediator in the PI3K/Akt signaling pathway, regulating a series of biological processes. In lipid metabolism, Akt activation regulates a series of gene expressions, including genes related to intracellular fatty acid synthesis. However, the regulatory mechanisms of Akt in dairy goat mammary lipid metabolism have not been elaborated. In this study, the coding sequences of goat Akt1 gene were cloned and analyzed. Gene expression of Akt1 in different lactation stages was also investigated...
January 11, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29320989/expression-of-vimentin-in-hair-follicle-growth-cycle-of-inner-mongolian-cashmere-goats
#16
Nai Rile, Zhihong Liu, Lixia Gao, Jingkai Qi, Meng Zhao, Yuchun Xie, Rui Su, Yanjun Zhang, Ruijun Wang, Jie Li, Hongmei Xiao, Jinquan Li
BACKGROUND: The growth of Inner Mongolian Cashmere goat skin hair follicle exhibits a periodic growth pattern. The hair growth cycle is distinguished as telogen, anagen, and catagen stages. The role of vimentin in the growth process of hair follicles is evident. To elucidate the mechanism underlying the vimentin activity in the growth cycle of hair follicles, transcriptome sequencing and liquid chromatography-tandem mass spectrometry were used to obtain the nucleic acid and amino acid sequences of VIIM gene and vimentin...
January 10, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29314531/evaluation-of-a-point-of-care-blood-glucose-monitor-in-healthy-goats
#17
Jane E Quandt, Michele Barletta, Karen K Cornell, Steeve Giguère, Erik H Hofmeister
OBJECTIVE: To assess agreement between a point-of-care glucometer (POCG) and a laboratory chemistry analyzer for blood glucose measurements in goats. DESIGN: Prospective study. SETTING: University teaching hospital. ANIMALS: Eighteen healthy adult goats. INVESTIGATIONS: Whole blood samples were obtained via jugular venipuncture prior to premedication with xylazine and butorphanol (T0), following premedication (T20), and after 1 hour of inhalant anesthesia (T60)...
January 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29313244/meningoencephaloradiculitis-following-infection-with-tick-borne-encephalitis-virus-case-report-and-review-of-the-literature
#18
Stephanie Du Four, Rembert Mertens, Wietse Wiels, Jacques De Keyser, Veronique Bissay, Anja Flamez
Tick borne encephalitis (TBE) is an infectious zoonotic disease caused by an RNA virus that is endemic to Central and Eastern Europe, Russia, and large parts of Asia. The tick borne encephalitis virus (TBEV) is transmitted through the saliva of infected ticks and infected goat milk. In the vast majority of cases, an infection with TBEV has a subclinical course. However, in some cases, it leads to neurological symptoms due to meningitis, meningoencephalitis, meningoencephalomyelitis, or meningoencephaloradiculitis...
January 8, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29313240/effect-of-ttc-treatment-on-immunohistochemical-quantification-of-collagen-iv-in-rat-brains-after-stroke
#19
Zhaojin Li, Nicole Bishop, Siu-Lung Chan, Marilyn J Cipolla
Although used extensively in stroke research, there is limited knowledge of how 2, 3, 5-triphenyltetrazolium chloride (TTC)-treated rat brain sections are altered and if they can be used for immunohistochemical quantification after staining with TTC. In the present study, we hypothesized that TTC treatment (TTC+) would not interfere with collagen IV immunohistochemical staining compared with non-TTC-treated (TTC-) brain slices. We further hypothesized that there would be no difference in autofluorescence or nonspecific secondary antibody fluorescence between TTC+ and TTC- brain slices...
January 8, 2018: Translational Stroke Research
https://www.readbyqxmd.com/read/29311427/blood-ionized-calcium-levels-and-acute-phase-blood-glucose-kinetics-in-goats-after-intramammary-infusion-of-lipopolysaccharide
#20
Yasunori Shinozuka, Kazuhiro Kawai, Reiichiro Sato, Akito Higashitani, Yoshiki Hamamoto, Miki Okita, Naoki Isobe
The aim of this study was to determine the blood ionized calcium (Ca) levels and acute-phase blood glucose kinetics in goats with mastitis induced by an intramammary challenge of lipopolysaccharide (LPS). Five goats were subjected to intramammary challenge of either LPS (10 µg) or saline (control). Some clinical manifestations (rectal temperature, pulse rate, respiration rate, ruminal motility, physical activity, and dehydration) were observed, and blood was collected for the measurement of several parameters [ionized and total Ca levels, blood glucose level, pH, and white blood count (WBC)] at 0 (just before challenge), 1-4, 6, 8, 12 and 24 hr post-challenge in both the LPS and control phases...
January 2, 2018: Journal of Veterinary Medical Science
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