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Dyspnoea

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https://www.readbyqxmd.com/read/28544079/cough-is-less-common-and-less-severe-in-systemic-sclerosis-associated-interstitial-lung-disease-compared-to-other-fibrotic-interstitial-lung-diseases
#1
Jasmine Z Cheng, Pearce G Wilcox, Ian Glaspole, Tamera J Corte, Darra Murphy, Cameron J Hague, Christopher J Ryerson
BACKGROUND AND OBJECTIVE: The objectives of this study were to determine the prevalence and characteristics of cough in idiopathic pulmonary fibrosis (IPF), chronic hypersensitivity pneumonitis (HP) and systemic sclerosis-associated interstitial lung disease (SSc-ILD). METHODS: Cough severity was measured in consecutive patients with IPF (n = 77), HP (n = 32) and SSc-ILD (n = 67) using a 10-cm visual analogue scale (VAS). Dyspnoea and quality of life were measured using established questionnaires...
May 23, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28536221/middle-lobe-syndrome-an-intriguing-presentation-of-tracheobronchial-amyloidosis
#2
Shekhar Kunal, Shashi Dhawan, Arvind Kumar, Ashok Shah
Pulmonary involvement in amyloidosis is a distinct rarity. This clinical entity usually presents as tracheobronchial amyloidosis (TBA). A 32-year-old, never-smoker man presented with episodic dyspnoea and wheezing along with cough and mucoid sputum. The chest radiograph was suggestive of a middle lobe syndrome (MLS). High-resolution CT (HRCT) of the chest confirmed the presence of MLS. In addition, HRCT showed circumferential thickening of the trachea and the main bronchi, with thickening of the posterior membranous wall of trachea...
May 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28532487/degree-of-dyspnoea-at-admission-and-discharge-in-patients-with-heart-failure-and-respiratory-diseases
#3
Lourdes Vicent, Juan Manuel Nuñez Olarte, Luis Puente-Maestu, Alicia Oliva, Juan Carlos López, Andrea Postigo, Irene Martín, Raquel Luna, Francisco Fernández-Avilés, Manuel Martínez-Sellés
BACKGROUND: Dyspnoea is a disabling symptom in patients admitted with heart failure (HF) and respiratory diseases (RD). The main aim of this study is to evaluate its intensity at admission and discharge and the relation with quality of life. We also describe its management, intensity, and evolution in HF and RD. METHODS: In this descriptive, cross-sectional study, we included prospectively all patients admitted with decompensated HF and chronic obstructive pulmonary disease (COPD)/pulmonary fibrosis during 4 months...
May 22, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28526439/-over-diagnosis-of-chronic-obstructive-pulmonary-disease-in-primary-care-prevalence-and-determining-factors
#4
R Golpe, M Díaz-Fernández, N Mengual-Macenlle, P Sanjuán-López, I Martín-Robles, E Cano-Jiménez
INTRODUCTION: COPD under-diagnosis is common in Primary Health Care medicine, due to the low use of spirometry, but there is less information about over-diagnosis of the disease in patients that have a clinical diagnosis of COPD. OBJECTIVE: The main objective of the study was to investigate the prevalence of COPD over-diagnosis in Primary Care medicine. Secondary objectives were to determine the factors associated with an incorrect clinical diagnosis of COPD and to analyse whether the pharmacological treatment is different for patients with correct or incorrect diagnosis...
May 17, 2017: Semergen
https://www.readbyqxmd.com/read/28522181/safety-and-efficacy-of-edaravone-in-well-defined-patients-with-amyotrophic-lateral-sclerosis-a-randomised-double-blind-placebo-controlled-trial
#5
(no author information available yet)
BACKGROUND: In a previous phase 3 study in patients with amyotrophic lateral sclerosis (ALS), edaravone did not show a significant difference in the Revised ALS Functional Rating Scale (ALSFRS-R) score compared with placebo. Post-hoc analysis of these data revealed that patients in an early stage with definite or probable diagnosis of ALS, defined by the revised El Escorial criteria, who met a select set of inclusion criteria showed a greater magnitude of effect than did the full study population...
May 15, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28521195/diabetes-and-impaired-glucose-metabolism-is-associated-with-more-cold-related-cardiorespiratory-symptoms
#6
Tiina Maria Ikäheimo, Jari Jokelainen, Juhani Hassi, Liisa Hiltunen, Sirkka Keinänen-Kiukaanniemi, Tiina Laatikainen, Pekka Jousilahti, Markku Peltonen, Leena Moilanen, Juha Saltevo, Simo Näyhä
AIMS: Diabetes and impaired glucose metabolism cause metabolic, neural and circulatory disturbances that may predispose to adverse cooling and related symptoms during the cold season. This study assessed the prevalence of cold-related cardiorespiratory symptoms in the general population according to glycaemic status. METHODS: The study population consisted of 2436 men and 2708 women aged 45-74years who participated in the National FINRISK cold sub-studies in 2002 and 2007...
May 4, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28511377/an-analysis-of-dynamic-pulmonary-functions-of-hypothyroid-patients
#7
Seethalakshmi Krishna Iyer, Sunil K Menon, Biju Bahuleyan
INTRODUCTION: Hypothyroidism is a silent epidemic of our times. In India, the prevalence of hypothyroidism is 11%. The effect of hypothyroidism on respiratory system is debatable with studies suggesting both obstructive and restrictive disease patterns. The symptoms range from mild dyspnoea to life-threatening respiratory failure. This study emphasizes the effect of hypothyroidism on dynamic respiratory functions. AIM: To find out the changes in dynamic respiratory functions (FVC, FEV1, FEV1% and PEFR) in both male and female hypothyroid patients within age group of 18-45 years...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511373/prevalence-of-nutritional-deficiency-anaemia-and-its-impact-on-scholastic-performance-among-undergraduate-medical-students
#8
Ningappa Asha Rani, Rajeshwari Arasegowda, Pramit Mukherjee, Shilpashree Yeliyur Dhananjay
INTRODUCTION: Nutritional deficiency anaemia can lead to development of headache, fatigue, lethargy, apathy, exertional dyspnoea, palpitations and tinnitus and thereby decrease the quality of everyday life to a great extent. Such symptoms may pose a hindrance for students in their academic life and have a negative impact on their career. AIM: To determine prevalence of nutritional deficiency anaemia and its correlation with academic performance among medical students...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28505689/-pain-management-in-palliative-care
#9
Martin B Steins, Corinna Eschbach, Matthias Villalobos, Michael Thomas
A consistent pain management together with treatment of dyspnoea belongs to the main issues in symptom control in particular in palliative thoracic oncology. Together with the medicamentous therapy the psychologic and social circumstances of the affected patients have to be considered as factors influencing the experience of pain. The therapeutic fundament according to the WHO guideline for cancer pain is the opiate based medicamentous adjustment combined with non-opioids. In principle, this should be performed preferably orally, as simply as possible, according to a fix drug schedule and individually adjusted to the needed dosage...
May 2017: Pneumologie
https://www.readbyqxmd.com/read/28501039/symptomatic-control-in-end-of-life-patients
#10
REVIEW
Mariana Alves, Rita Abril, Isabel Galriça Neto
End-of-life patients present a variety of symptoms that cause suffering for them and their respective families. Health professionals throughout their university, internship and medical careers are ill-prepared to manage and improve the quality of life of these patients. This article aims to provide basic skills in the symptomatic management of end-of-life patients, focusing in particular on the control of pain, dyspnoea, fatigue, nausea, vomiting and anorexia. It also aims to draw attention to basic concepts of control concerning refractory symptoms and palliative sedation...
January 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28500116/a-53-year-old-man-with-dyspnoea-respiratory-failure-consistent-with-infliximab-induced-acute-interstitial-pneumonitis-after-an-accelerated-induction-dosing-schedule
#11
Rymon Rofaiel, Sonny Kohli, Marco Mura, Seyed M Hosseini-Moghaddam
A 53-year-old man with ulcerative colitis (UC) suffered fatal acute interstitial pneumonitis (AIP) post completing an accelerated infliximab induction course. This is the first case reported in this setting. A literature review found four similar cases of infliximab-induced interstitial lung disease in the setting of treating patients with UC using standard infliximab regimens had successful treatment of the subjects post infliximab discontinuation. Unfortunately, the patient we are presenting, who had an accelerated infliximab induction course, did not survive...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28499034/functional-disability-and-its-predictors-in-systemic-sclerosis-a-study-from-the-desscipher-project-within-the-eustar-group
#12
Veronika K Jaeger, Oliver Distler, Britta Maurer, Laszlo Czirják, Veronika Lóránd, Gabriele Valentini, Serena Vettori, Francesco Del Galdo, Giuseppina Abignano, Christopher Denton, Svetlana Nihtyanova, Yannick Allanore, Jerome Avouac, Gabriele Riemekasten, Elise Siegert, Dörte Huscher, Marco Matucci-Cerinic, Serena Guiducci, Marc Frerix, Ingo H Tarner, Beata Garay Toth, Beat Fankhauser, Jörg Umbricht, Anastasia Zakharova, Carina Mihai, Franco Cozzi, Sule Yavuz, Nicolas Hunzelmann, Simona Rednic, Alessandra Vacca, Tim Schmeiser, Valeria Riccieri, Paloma García de la Peña Lefebvre, Armando Gabrielli, Brigitte Krummel-Lorenz, Duska Martinovic, Codrina Ancuta, Vanessa Smith, Ulf Müller-Ladner, Ulrich A Walker
Objectives.: The multisystem manifestations of SSc can greatly impact patients' quality of life. The aim of this study was to identify factors associated with disability in SSc. Methods.: SSc patients from the prospective DeSScipher cohort who had completed the scleroderma health assessment questionnaire (SHAQ), a disability score that combines the health assessment questionnaire and five visual analogue scales, were included in this analysis. The effect of factors possibly associated with disability was analysed with multiple linear regressions...
May 11, 2017: Rheumatology
https://www.readbyqxmd.com/read/28496988/randomised-controlled-field-study-to-evaluate-the-efficacy-and-clinical-safety-of-a-single-8%C3%A2-mg-kg-injectable-dose-of-marbofloxacin-compared-with-one-or-two-doses-of-7-5%C3%A2-mg-kg-injectable-enrofloxacin-for-the-treatment-of-actinobacillus-pleuropneumoniae-infections
#13
Erik Grandemange, Pierre-Alexandre Perrin, Dejean Cvejic, Miriam Haas, Tim Rowan, Klaus Hellmann
BACKGROUND: Acute outbreaks of Actinobacillus pleuropneumoniae (APP) require rapid, effective, parenteral antimicrobial treatment. The efficacy and safety of a single, short-acting, high dose of marbofloxacin (Forcyl® swine 160 mg/mL) compared with 1 or 2 doses of 7.5 mg/kg enrofloxacin in APP outbreaks in European farms was studied. METHODS: A controlled, randomised block, blinded, multicentre, field study was conducted on four farms with acute respiratory disease associated with APP...
2017: Porcine Health Management
https://www.readbyqxmd.com/read/28494643/randomised-clinical-trial-of-early-specialist-palliative-care-plus-standard-care-versus-standard-care-alone-in-patients-with-advanced-cancer-the-danish-palliative-care-trial
#14
Mogens Groenvold, Morten Aagaard Petersen, Anette Damkier, Mette Asbjoern Neergaard, Jan Bjoern Nielsen, Lise Pedersen, Per Sjøgren, Annette Sand Strömgren, Tove Bahn Vejlgaard, Christian Gluud, Jane Lindschou, Peter Fayers, Irene J Higginson, Anna Thit Johnsen
BACKGROUND: Beneficial effects of early palliative care have been found in advanced cancer, but the evidence is not unequivocal. AIM: To investigate the effect of early specialist palliative care among advanced cancer patients identified in oncology departments. SETTING/PARTICIPANTS: The Danish Palliative Care Trial (DanPaCT) (ClinicalTrials.gov NCT01348048) is a multicentre randomised clinical trial comparing early referral to a specialist palliative care team plus standard care versus standard care alone...
May 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28493418/muscle-mass-and-association-to-quality-of-life-in-non-small-cell-lung-cancer-patients
#15
Asta Bye, Bjørg Sjøblom, Tore Wentzel-Larsen, Bjørn H Grønberg, Vickie E Baracos, Marianne J Hjermstad, Nina Aass, Roy M Bremnes, Øystein Fløtten, Marit Jordhøy
BACKGROUND: Cancer wasting is characterized by muscle loss and may contribute to fatigue and poor quality of life (QoL). Our aim was to investigate associations between skeletal muscle index (SMI) and skeletal muscle radiodensity (SMD) and selected QoL outcomes in advanced non-small cell lung cancer (NSCLC) at diagnosis. METHODS: Baseline data from patients with stage IIIB/IV NSCLC and performance status 0-2 enrolled in three randomized trials of first-line chemotherapy (n = 1305) were analysed...
May 10, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28492084/prehospital-triage-of-patients-suffering-severe-dyspnoea-using-n-terminal-pro-brain-natriuretic-peptide-the-prebnp-trial-a-randomised-controlled-clinical-trial
#16
Morten T Bøtker, Maren T Jørgensen, Carsten Stengaard, Sophie-Charlott Seidenfaden, Mona Tarpgaard, Asger Granfeldt, Tanja Ø Mortensen, Thorbjørn Grøfte, Kristian D Friesgaard, Rikke Mærkedahl, Anette B Pedersen, Simon Lundorff, Troels Martin Hansen, Hans Kirkegaard, Erika F Christensen, Christian J Terkelsen
PURPOSE: The purpose of this study was to examine whether the addition of brain natriuretic peptide measurement to the routine diagnostic work-up by prehospital critical care team physicians improves triage in patients with severe dyspnoea. METHODS: Prehospital critical care team physicians randomly assigned patients older than 18 years with severe dyspnoea to routine diagnostic work-up or diagnostic work-up with incorporated point-of-care N-terminal pro-brain natriuretic peptide (NT-proBNP) measurement...
May 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28490618/21-year-old-with-exertional-dyspnoea
#17
Tiffany Chen, Tara L Jones, Eric V Krieger
No abstract text is available yet for this article.
May 10, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28490555/telehealthcare-for-patients-suffering-from-chronic-obstructive-pulmonary-disease-effects-on-health-related-quality-of-life-results-from-the-danish-telecare-north-cluster-randomised-trial
#18
Pernille Heyckendorff Lilholt, Flemming Witt Udsen, Lars Ehlers, Ole K Hejlesen
OBJECTIVE: To assess the effect of telehealthcare compared with usual practice in patients with chronic obstructive pulmonary disease (COPD). DESIGN: A cluster-randomised trial with 26 municipal districts that were randomly assigned either to an intervention group whose members received telehealthcare in addition to usual practice or to a control group whose members received usual practice only (13 districts in each arm). SETTING: Twenty-six municipal districts in the North Denmark Region of Denmark...
May 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28485200/assessment-of-early-treatment-response-by-rapid-cardiothoracic-ultrasound-in-acute-heart-failure-cardiac-filling-pressures-pulmonary-congestion-and-mortality
#19
Jonas Öhman, Veli-Pekka Harjola, Pasi Karjalainen, Johan Lassus
BACKGROUND: It is unclear how to optimally monitor acute heart failure (AHF) patients. We evaluated the timely interplay of cardiac filling pressures, brain natriuretic peptides (BNPs), lung ultrasound (LUS) and symptoms during AHF treatment. METHODS: We enrolled 60 patients who had been hospitalised for AHF. Patients were examined with a rapid cardiothoracic ultrasound (CaTUS) protocol, combining LUS and focused echocardiographic evaluation of cardiac filling pressures (i...
May 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28482883/rescue-medication-use-as-a-patient-reported-outcome-in-copd-a-systematic-review-and-regression-analysis
#20
Yogesh Suresh Punekar, Sheetal Sharma, Ankit Pahwa, Jitender Takyar, Ian Naya, Paul W Jones
BACKGROUND: Reducing rescue medication use is a guideline-defined goal of asthma treatment, however, little is known about the validity of rescue medicine use as a marker of symptoms in chronic obstructive pulmonary disease (COPD). To improve patient outcomes, greater insight is needed into the relationship between rescue medication use and alternative COPD outcomes. METHODS: A systematic search of electronic databases (Embase®, MEDLINE® and Cochrane CENTRAL) was conducted from database start to 26 May, 2015...
May 8, 2017: Respiratory Research
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