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Breathlessness

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https://www.readbyqxmd.com/read/28320369/breathlessness-and-presentation-to-the-emergency-department-a-survey-and-clinical-record-review
#1
Ann Hutchinson, Alistair Pickering, Paul Williams, J Martin Bland, Miriam J Johnson
BACKGROUND: Breathlessness is a frequently occurring symptom of cardiorespiratory conditions and is a common cause of emergency department presentation. The aim of this study was to estimate the prevalence of acute-on-chronic breathlessness as a cause for presentation to the major emergencies area of the emergency department. METHODS: A prospective patient self-report survey and clinical record review of consecutive attendees to the major emergencies area of the emergency department in a single tertiary hospital between 12/5/14 and 29/5/14 was conducted...
March 20, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28303156/acu-tens-reduces-breathlessness-during-exercise-in-people-with-chronic-obstructive-pulmonary-disease
#2
Shirley P C Ngai, Lissa M Spencer, Alice Y M Jones, Jennifer A Alison
Background. Exertional dyspnoea limits level of physical activity in people with Chronic Obstructive Pulmonary Disease (COPD). This randomized, double-blinded, crossover study evaluated the effect of Acu-TENS, application of Transcutaneous Electrical Nerve Stimulation on acupoints, on breathlessness during exercise in people with COPD. Methods. Twenty-one participants, mean% predicted FEV1  50 ± 21%, attended assessment followed by two intervention days, one week apart. On each intervention day, participants performed two endurance shuttle walk tests (ESWT) (Walk 1 and Walk 2)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28294498/respiratory-health-status-is-impaired-in-uk-hiv-positive-adults-with-virologically-suppressed-hiv-infection
#3
J Brown, J A McGowan, H Chouial, S Capocci, C Smith, D Ivens, M Johnson, L Sathia, R Shah, F C Lampe, A Rodger, M Lipman
OBJECTIVES: We sought to evaluate whether people living with HIV (PLWH) using effective antiretroviral therapy (ART) have worse respiratory health status than similar HIV-negative individuals. METHODS: We recruited 197 HIV-positive and 93 HIV-negative adults from HIV and sexual health clinics. They completed a questionnaire regarding risk factors for respiratory illness. Respiratory health status was assessed using the St George's Respiratory Questionnaire (SGRQ) and the Medical Research Council (MRC) breathlessness scale...
March 13, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28290765/subjective-responses-to-interval-and-continuous-exercise-in-adults-with-exercise-induced-bronchoconstriction
#4
Carley O'Neill, Shilpa Dogra
BACKGROUND: Exercise triggers asthma symptoms among adults with exercise induced bronchoconstriction (EIBC). This may lead to lower physical activity levels among this population. The purpose of this study was to assess perceived exertion (RPE), perceived breathlessness (RPD), affect (FS), and physical activity enjoyment during and following an acute bout of high intensity interval exercise (HIIE), moderate intensity interval (MIIE) and moderate intensity continuous exercise (MICE) in adults with EIBC...
March 14, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28286651/trajectories-of-a-set-of-ten-functional-somatic-symptoms-from-adolescence-to-middle-age
#5
Tapio Nummi, Pekka Virtanen, Päivi Leino-Arjas, Anne Hammarström
BACKGROUND: Functional somatic symptoms (FSS), or symptoms without a clear medical explanation are a considerable challenge for health care systems. There is no general consensus as to which symptoms should be regarded functional. Few longitudinal studies on the development of FSS exist and these have mainly been based on the assumption that the factorial structure of a FSS scores variable remains invariant over time. When the analysis covers longer periods of the life course, this may be challenged...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28284169/salivary-diurnal-cortisol-profiles-in-patients-suffering-from-chronic-breathlessness-receiving-supportive-and-palliative-care-services-a-cross-sectional-study
#6
Richella Ryan, Angela Clow, Anna Spathis, Nina Smyth, Stephen Barclay, Marie Fallon, Sara Booth
Chronic breathlessness is a common source of psychological and physical stress in patients with advanced or progressive disease, suggesting that hypothalamic-pituitary-adrenal (HPA) axis dysregulation may be prevalent. The aim of this study was to measure the salivary diurnal cortisol profile in patients receiving supportive and palliative care for a range of malignant and non-malignant conditions and to compare the profile of those experiencing moderate-to-severe disability due to breathlessness against that of patients with mild/no breathlessness and that of healthy controls...
January 27, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28283487/from-breathless-to-failure-symptom-onset-and-diagnostic-meaning-in-patients-with-heart-failure-a-qualitative-study
#7
C J Taylor, F D R Hobbs, T Marshall, F Leyva-Leon, N Gale
OBJECTIVES: To explore 2 key points in the heart failure diagnostic pathway-symptom onset and diagnostic meaning-from the patient perspective. DESIGN: Qualitative interview study. SETTING: Participants were recruited from a secondary care clinic in central England following referral from primary care. PARTICIPANTS: Over age 55 years with a recent (<1 year) diagnosis of heart failure confirmed by a cardiologist following initial presentation to primary care...
March 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28282499/non-opioid-medications-for-the-relief-of-chronic-breathlessness-current-evidence
#8
Carlo Barbetta, David C Currow, Miriam J Johnson
To evaluate systematically randomised clinical trials investigating non-opioid medications for the management and treatment of chronic breathlessness. Areas Covered: The evidence for the role of benzodiazepines, anxiolytics, selective serotonin re-uptake inhibitors (SSRIs), tricyclic antidepressants, antihistamines, cannabinoids, nebulized furosemide and herbal-based treatments were critically reviewed. Search of the Clinical Trials Registry (Clinicaltrial.gov) identified ongoing studies expected to generate new data in the near future in several classes of non-opioid medications for their net effect on chronic breathlessness...
March 10, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28281829/sensing-the-airs-the-cultural-context-for-breathing-and-breathlessness-in-uruguay
#9
Megan Wainwright
The sensory experience of breathing, particularly the sensation of breathlessness in the case of chronic obstructive pulmonary disease (COPD), is a rich though understudied topic in medical anthropology. Fieldwork in Uruguay made it clear to me that to study the sensorial experience of breathlessness, I would also have to study the widely shared cultural conceptualizations and practices surrounding air, breath, and health. In this article, I illustrate ethnographically how the experience of breathing and breathlessness is closely tied to perceptions of air outside the body - in particular humidity, temperature change, wind, and contamination...
February 7, 2017: Medical Anthropology
https://www.readbyqxmd.com/read/28277858/pathophysiology-of-dyspnea-in-copd
#10
Antonio Anzueto, Marc Miravitlles
Dyspnea refers to the sensation of breathlessness, shortness of breath, or difficulty breathing that is commonly observed in patients with respiratory and cardiac disease. In the United States alone, dyspnea is reported in up to 4 million all-cause emergency room visits annually. Dyspnea can be a symptom of several different underlying physical conditions, typically involving the lung and heart. Indeed, it is an important symptom in chronic obstructive pulmonary disease (COPD), where it is associated with limited physical activity, increased anxiety and depression, decreased health-related quality of life (HRQoL), and reduced survival...
March 17, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28275174/physiological-and-clinical-relevance-of-exercise-ventilatory-efficiency-in-copd
#11
REVIEW
J Alberto Neder, Danilo C Berton, Flavio F Arbex, Maria Clara Alencar, Alcides Rocha, Priscila A Sperandio, Paolo Palange, Denis E O'Donnell
Exercise ventilation (V'E) relative to carbon dioxide output (V'CO2 ) is particularly relevant to patients limited by the respiratory system, e.g. those with chronic obstructive pulmonary disease (COPD). High V'E-V'CO2 (poor ventilatory efficiency) has been found to be a key physiological abnormality in symptomatic patients with largely preserved forced expiratory volume in 1 s (FEV1). Establishing an association between high V'E-V'CO2 and exertional dyspnoea in mild COPD provides evidence that exercise intolerance is not a mere consequence of detraining...
March 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28275024/levetiracetam-induced-eosinophilic-pneumonia
#12
Aisling Fagan, Jonathan Fuld, Elaine Soon
Levetiracetam is widely regarded as a benign antiepileptic drug, compared to older antiepileptic medication. We report a case of eosinophilic pneumonia due to levetiracetam use in a non-smoking woman aged 59 years with no previous respiratory history. Our patient presented with exertional breathlessness and marked desaturation on exertion. She displayed 'reverse bat-wing' infiltrates on her chest radiograph and peripheral eosinophilia on a complete blood count. Her symptoms, radiology and peripheral eosinophilia resolved completely with cessation of levetiracetam and a course of prednisolone...
March 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28272068/rare-disease-heralded-by-pulmonary-manifestations-avoiding-pitfalls-of-an-asthma-label
#13
S Bajaj, M Muranjan, S Karande, D Prabhat
Pulmonary manifestations are seldom recognized as symptoms of storage disorders. The report describes the diagnostic journey in a 30-month-old male infant, born of a third-degree consanguineous marriage referred to our institute as severe persistent asthma. History revealed that the child had progressively worsening breathlessness and persistent dry cough not associated with fever but accompanied by weight loss. On physical examination, there was growth failure, respiratory distress, clubbing, hepatosplenomegaly, and occasional rhonchi...
March 3, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28256404/panic-disorder-in-patients-presenting-to-the-emergency-department-with-chest-pain-prevalence-and-presenting-symptoms
#14
Jaimi H Greenslade, Tracey Hawkins, William Parsonage, Louise Cullen
BACKGROUND: Patients with panic disorder experience symptoms such as palpitations, chest pain, dizziness, and breathlessness. Consequently, they may attend the Emergency Department (ED) to be assessed for possible emergency medical conditions. Recognition of panic disorder within the ED is low. We sought to establish the prevalence of panic disorder in patients presenting to the for ED investigation of potential acute coronary syndrome. We also sought to characterise the cohort of patients with panic disorder in terms of presenting symptoms, risk factors, medical history and major adverse cardiac events (MACE)...
February 16, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28248580/a-smoldering-case-of-breathlessness-exposed-by-bedside-ultrasound
#15
Hailey Hobbs, Brian Buchanan, Robert Arntfield
No abstract text is available yet for this article.
March 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28239994/aortic-stenosis-in-dialysis-patients
#16
REVIEW
Yousif Ahmad, Michael F Bellamy, Christopher S R Baker
Aortic valve stenosis occurs 10-20 years earlier in patients on dialysis compared with the general population. This is likely related to the exposure of the valve to a milieu that predisposes to calcification as well as increased shear stress across the valve. Objective assessment of stenosis severity is largely made using echocardiography though accurate interpretation requires an understanding of the potential pitfalls of the technique and the influence of cardiac output upon the gradient measured across the valve...
February 26, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28237944/could-kinesiology-taping-help-mitigate-pain-breathlessness-and-abdominal-related-symptoms-in-cancer
#17
Gourav Banerjee, Alison Rose, Michelle Briggs, Mark I Johnson
We present the case of a woman who was an amateur athlete diagnosed with primary breast cancer, and 10 years later with terminal metastatic cancer. This case report was prepared posthumously in co-operation with her next of kin (husband). The patient first presented to a sports physiotherapist (AR) for her pain-management and to help maintain physical fitness so that she could continue with sports and an active lifestyle. The patient continued with physiotherapy for several months to enable her to be active...
February 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28220381/pharmacological-management-of-people-living-with-end-stage-chronic-obstructive-pulmonary-disease
#18
Victoria Dalgliesh, Hilary Pinnock
Supportive care and pharmacological treatment can improve the quality of life of people with end-stage chronic obstructive pulmonary disease (COPD) who cope on a daily basis with substantial physical, psychological, social and spiritual morbidity. Smoking cessation is the only intervention that reduces the rate of progression of COPD, but evidence-based drug treatments and non-pharmacological strategies can relieve symptoms and reduce the impact of exacerbations. People with severe COPD live with increasingly troublesome breathlessness and other symptoms such as fatigue, pain, sputum production and weight loss...
April 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28211789/the-cortical-connectivity-of-the-periaqueductal-gray-and-the-conditioned-response-to-the-threat-of-breathlessness
#19
Olivia K Faull, Kyle Ts Pattinson
Previously we observed differential activation in individual columns of the periaqueductal grey (PAG) during breathlessness and its conditioned anticipation (Faull et al., 2016b). Here, we have extended this work by determining how the individual columns of the PAG interact with higher cortical centres, both at rest and in the context of breathlessness threat. Activation was observed in ventrolateral PAG (vlPAG) and lateral PAG (lPAG), where activity scaled with breathlessness intensity ratings, revealing a potential interface between sensation and cognition during breathlessness...
February 17, 2017: ELife
https://www.readbyqxmd.com/read/28208930/precautionary-measures-for-successful-open-heart-surgery-in-g6pd-deficient-patient-a-case-report
#20
Rupesh Kumar
Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is among the most common enzymatic disorders of red blood cells. Cardiac surgeries on this group of individuals are associated with an additional risk in terms of impaired oxygenation, prolonged ventilation and increased risk of haemolysis. These patients have a very low threshold for haemolysis due to oxidative stress. Many commonly used drugs also predispose the individual for haemolysis when they are subjected to surgery. Here we present a known case of G6PD deficient patient with symptoms of breathlessness for the last nine years who was taken for surgery with pre-planned precautionary measures to avoid unnecessary haemolysis...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
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