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https://www.readbyqxmd.com/read/28743100/studies-on-secondary-metabolite-profiling-anti-inflammatory-potential-in-vitro-photoprotective-and-skin-aging-related-enzyme-inhibitory-activities-of-malaxis-acuminata-a-threatened-orchid-of-nutraceutical-importance
#1
Biswajit Bose, Hiranjit Choudhury, Pramod Tandon, Suman Kumaria
Malaxis acuminata D. Don., a small, terrestrial orchid, is endemic to tropical Himalayas at an altitude of 1200-2000m asl. The dried pseudobulbs are important ingredients of century old ayurvedic drug 'Ashtavarga' and a polyherbal immune-booster nutraceutical 'Chyavanprash', known to restore vigour, vitality and youthfulness. Considering tremendous medicinal importance of this threatened orchid species, a detailed study was undertaken for the first time to address its antioxidant potential, secondary metabolite contents and biological activities against skin-aging related enzymes (anti-collagenase, anti-elastase, anti-tyrosinase and xanthine oxidase) and anti-inflammatory activity (5-lipoxygenase and hyaluronidase) in different plant parts of wild and in vitro-derived plants of M...
July 12, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28742865/a-novel-mitochondrial-genome-of-arborophila-and-new-insight-into-arborophila-evolutionary-history
#2
Chaochao Yan, Biqin Mou, Yang Meng, Feiyun Tu, Zhenxin Fan, Megan Price, Bisong Yue, Xiuyue Zhang
The lineage of the Bar-backed Partridge (Arborophila brunneopectus) was investigated to determine the phylogenetic relationships within Arborophila as the species is centrally distributed within an area covered by the distributions of 22 South-east Asian hill partridge species. The complete mitochondrial genome (mitogenome) of A. brunneopectus was determined and compared with four other hill partridge species mitogenomes. NADH subunit genes are radical in hill partridge mitogenomes and contain the most potential positive selective sites around where variable sites are abundant...
2017: PloS One
https://www.readbyqxmd.com/read/28741441/atmospheric-pressure-and-abdominal-aortic-aneurysm-rupture-results-from-a-time-series-analysis-and-case-crossover-study
#3
Bas B L Penning de Vries, Joé L P Kolkert, Robbert Meerwaldt, Rolf H H Groenwold
BACKGROUND: Associations between atmospheric pressure and abdominal aortic aneurysm (AAA) rupture risk have been reported, but empirical evidence is inconclusive and largely derived from studies that did not account for possible nonlinearity, seasonality, and confounding by temperature. METHODS: Associations between atmospheric pressure and AAA rupture risk were investigated using local meteorological data and a case series of 358 patients admitted to hospital for ruptured AAA during the study period, January 2002 to December 2012...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28741038/changes-in-appetite-energy-intake-body-composition-and-circulating-ghrelin-constituents-during-an-incremental-trekking-ascent-to-high-altitude
#4
Jamie Matu, John O'Hara, Neil Hill, Sarah Clarke, Christopher Boos, Caroline Newman, David Holdsworth, Theocharis Ispoglou, Lauren Duckworth, David Woods, Adrian Mellor, Kevin Deighton
PURPOSE: Circulating acylated ghrelin concentrations are associated with altitude-induced anorexia in laboratory environments, but have never been measured at terrestrial altitude. This study examined time course changes in appetite, energy intake, body composition, and ghrelin constituents during a high-altitude trek. METHODS: Twelve participants [age: 28(4) years, BMI 23.0(2.1) kg m(-2)] completed a 14-day trek in the Himalayas. Energy intake, appetite perceptions, body composition, and circulating acylated, des-acylated, and total ghrelin concentrations were assessed at baseline (113 m, 12 days prior to departure) and at three fixed research camps during the trek (3619 m, day 7; 4600 m, day 10; 5140 m, day 12)...
July 24, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28738469/-analysis-on-geographic-distribution-of-high-blood-pressure-prevalence-in-children-and-adolescents-aged-7-18-years-in-china-2014
#5
Y H Dong, Z Y Zou, Z H Wang, S Wang, Z P Yang, Y J Chen, J Ma
Objective: To understand and evaluate the characteristics of geographic distribution of high blood pressure prevalence in children and adolescents aged 7-18 years in China in 2014, and provide evidence for the prevention of hypertension in children and adolescents. Methods: The data of 2014 Chinese National Surveys on Students Constitution and Health conducting 31 provinces (except Hong Kong, Macao and Taiwan) were collected. A total of 216 299 children and adolescents who had complete blood pressure records were selected as study subjects...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28735726/molecular-adaptive-convergence-in-the-%C3%AE-globin-in-subterranean-octodontid-rodents
#6
Ivanna H Tomasco, Nicolás Boullosa, Federico G Hoffmann, Enrique P Lessa
Tuco-tucos (Ctenomys) and related coruros (Spalacopus) are South American subterranean rodents. An energetically demanding lifestyle within the hypoxic/hypercapnic underground atmosphere may change the selective regime on genes involved in O2 transport in blood. In addition, some species of tuco-tucos may be found at high altitude, thus facing additional reductions in changes O2 availabily. We examined sequence variation in the alpha globin subunit gene of hemoglobine in these lineages, within a robust phylogenetic context...
July 20, 2017: Gene
https://www.readbyqxmd.com/read/28735657/l-arginine-attenuates-hypobaric-hypoxia-induced-increase-in-ornithine-decarboxylase-1
#7
Li Yuhong, Bai Zhengzhong, Tang Feng, Yang Quanyu, Ri-Li Ge
BACKGROUND: Chronic hypoxia-induced pulmonary hypertension and vascular remodeling have been shown to be associated with ornithine decarboxylase 1 (ODC1). However, few animal studies have investigated the role of ODC1 in acute hypoxia. OBJECTIVES: We investigated ODC1 gene expression, morphologic and functional changes, and the effect of L-arginine as an attenuator in lung tissues of rats exposed to acute hypobaric hypoxia at a simulated altitude of 6000 m. METHODS: Sprague-Dawley rats exposed to simulated hypobaric hypoxia (6000 m) for 24, 48, or 72 hours were treated with L-arginine (L-arginine group, 20 mg/100 g intraperitoneal; n=15) or untreated (non-L-arginine group, n=15)...
July 20, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28735560/promotion-of-fracture-healing-by-conjugated-linoleic-acid-in-rats
#8
Zhongshu Shan, Zong-Ping Luo, Xiaozhong Shen, Liang Chen
BACKGROUND: The ability of fracture healing in Tibetans is significantly superior to Chinese Hans, which may attribute to factors from diet, altitude to physical conditions. Conjugated linoleic acid (CLA) is an important ingredient in Tibetan diet, playing a role in antioxidation, antiatherosclerosis, and decrease in body fat accumulation.  Methods: This study further quantified CLA effect in fracture healing in rats using combined structural evaluation (X-ray and micro-computed tomography), biomechanical test, and histological examination...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28735090/impacts-of-the-2003-and-2015-summer-heatwaves-on-permafrost-affected-rock-walls-in-the-mont-blanc-massif
#9
L Ravanel, F Magnin, P Deline
Rockfall is one of the main geomorphological processes that affects the evolution and stability of rock-walls. At high elevations, rockfall is largely climate-driven, very probably because of the warming of rock-wall permafrost. So with the ongoing global warming that drives the degradation of permafrost, the related hazards for people and infrastructure could continue to increase. The heatwave of summer 2015, which affected Western Europe from the end of June to August, had a serious impact on the stability of high-altitude rock-walls, including those in the Mont Blanc massif...
July 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28732756/health-of-high-altitude-pilgrims-a-neglected-topic
#10
EDITORIAL
Sanjeeb Sudarshan Bhandari, Pranawa Koirala
HASH(0x3ff4920)
July 18, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28732403/ecosystem-service-trade-offs-and-their-influencing-factors-a-case-study-in-the-loess-plateau-of-china
#11
Qiang Feng, Wenwu Zhao, Bojie Fu, Jingyi Ding, Shuai Wang
Soil erosion control (SEC), carbon sequestration (CAS), and soil moisture (SMO) strongly interact in the semi-arid Loess Plateau. Since SMO has supportive effects on SEC and CAS, it can be considered as ecosystem service (ES), and there is an immediate need to coordinate the relationships among these ecosystem services (ESs) to promote the sustainability of vegetation recovery. In this study, we quantified the ESs, ES trade-offs, and the environmental factors in 151 sample plots in the Ansai watershed, and we used a redundancy analysis (RDA) to clarify the effects of environmental factors on these ESs and their trade-offs...
July 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28732027/serum-irisin-and-myostatin-levels-after-2-weeks-of-high-altitude-climbing
#12
Ewa Śliwicka, Tomasz Cisoń, Zbigniew Kasprzak, Alicja Nowak, Łucja Pilaczyńska-Szcześniak
Exposure to high-altitude hypoxia causes physiological and metabolic adaptive changes by disturbing homeostasis. Hypoxia-related changes in skeletal muscle affect the closely interconnected energy and regeneration processes. The balance between protein synthesis and degradation in the skeletal muscle is regulated by several molecules such as myostatin, cytokines, vitamin D, and irisin. This study investigates changes in irisin and myostatin levels in male climbers after a 2-week high-altitude expedition, and their association with 25(OH)D and indices of inflammatory processes...
2017: PloS One
https://www.readbyqxmd.com/read/28731986/the-effect-of-sex-on-heart-rate-variability-at-high-altitude
#13
Christopher John Boos, Emma Vincent, Adrian Mellor, John O'Hara, Caroline Newman, Richard Cruttenden, Phylip Scott, Mark Cooke, Jamie Matu, David Richard Woods
There is evidence to suggest that high altitude (HA) exposure leads to a fall in heart rate variability (HRV) that is linked to the development of acute mountain sickness (AMS). The effects of sex on changes in HRV at HA and its relationship to AMS are unknown. METHODS: HRV (5-minute single lead ECG) was measured in 63 healthy adults (41 men and 22 women) aged 18-56 years at sea level (SL) and during a HA trek at 3619m, 4600m and 5140m respectively. The main effects of altitude (SL, 3619, 4600 and 5140m) and sex (men vs women) and their potential interaction were assessed using a Factorial Repeated Measures ANOVA...
July 20, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28730606/technical-note-empirical-altitude-correction-factors-for-well-chamber-measurements-of-permanent-prostate-and-breast-seed-implant-sources
#14
Elizabeth Watt, David P Spencer, Tyler Meyer
PURPOSE: Previous studies in the literature have measured an altitude effect for low-energy brachytherapy seeds; a correction factor applied in addition to PTP to account for the breakdown of Bragg-Gray cavity theory at low energies in well-type ionization chambers. In clinical practice, many centres use altitude correction factors that are not seed-model-specific. The purpose of this work is to present altitude correction factors for several seed models without documented factors in the literature...
July 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28726755/control-measurements-of-crane-rails-performed-by-terrestrial-laser-scanning
#15
Klemen Kregar, Jan Možina, Tomaž Ambrožič, Dušan Kogoj, Aleš Marjetič, Gašper Štebe, Simona Savšek
This article presents a method for measuring the geometry of crane rails with terrestrial laser scanning (TLS). Two sets of crane rails were divided into segments, their planes were adjusted, and the characteristic rail lines were defined. We used their profiles to define the positional and altitude deviations of the rails, the span and height difference between the two rails, and we also verified that they complied with the Eurocode 3 standard. We tested the method on crane rails at the hydroelectric power plant in Krško and the thermal power plant in Brestanica...
July 20, 2017: Sensors
https://www.readbyqxmd.com/read/28726295/antioxidant-defense-and-oxidative-damage-vary-widely-among-high-altitude-residents
#16
Allison J Janocha, Suzy A A Comhair, Buddha Basnyat, Maniraj Neupane, Amha Gebremedhin, Anam Khan, Kristin S Ricci, Renliang Zhang, Serpil C Erzurum, Cynthia M Beall
OBJECTIVES: People living at high altitude experience unavoidable low oxygen levels (hypoxia). While acute hypoxia causes an increase in oxidative stress and damage despite higher antioxidant activity, the consequences of chronic hypoxia are poorly understood. The aim of the present study is to assess antioxidant activity and oxidative damage in high-altitude natives and upward migrants. METHODS: Individuals from two indigenous high-altitude populations (Amhara, n = 39), (Sherpa, n = 34), one multigenerational high-altitude population (Oromo, n = 42), one upward migrant population (Nepali, n = 12), and two low-altitude reference populations (Amhara, n = 29; Oromo, n = 18) provided plasma for measurement of superoxide dismutase (SOD) activity as a marker of antioxidant capacity, and urine for measurement of 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a marker of DNA oxidative damage...
July 20, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28725419/tree-species-diversity-promotes-aboveground-carbon-storage-through-functional-diversity-and-functional-dominance
#17
Sylvanus Mensah, Ruan Veldtman, Achille E Assogbadjo, Romain Glèlè Kakaï, Thomas Seifert
The relationship between biodiversity and ecosystem function has increasingly been debated as the cornerstone of the processes behind ecosystem services delivery. Experimental and natural field-based studies have come up with nonconsistent patterns of biodiversity-ecosystem function, supporting either niche complementarity or selection effects hypothesis. Here, we used aboveground carbon (AGC) storage as proxy for ecosystem function in a South African mistbelt forest, and analyzed its relationship with species diversity, through functional diversity and functional dominance...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725381/extending-bioacoustic-monitoring-of-birds-aloft-through-flight-call-localization-with-a-three-dimensional-microphone-array
#18
Phillip M Stepanian, Kyle G Horton, David C Hille, Charlotte E Wainwright, Phillip B Chilson, Jeffrey F Kelly
Bioacoustic localization of bird vocalizations provides unattended observations of the location of calling individuals in many field applications. While this technique has been successful in monitoring terrestrial distributions of calling birds, no published study has applied these methods to migrating birds in flight. The value of nocturnal flight call recordings can increase with the addition of three-dimensional position retrievals, which can be achieved with adjustments to existing localization techniques...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725367/the-effect-of-seed-traits-on-geographic-variation-in-body-size-and-sexual-size-dimorphism-of-the-seed-feeding-beetle-acanthoscelides-macrophthalmus
#19
Eloísa B Haga, Marcelo N Rossi
Explaining large-scale patterns of variation in body size has been considered a central question in ecology and evolutionary biology because several life-history traits are directly linked to body size. For ectothermic organisms, little is known about what processes influence geographic variation in body size. Changes in body size and sexual size dimorphism (SSD) have been associated with environmental variables, particularly for Bruchinae insects, which feed exclusively on seeds during the larval stage. However, the effect of important seed traits on body size variation has rarely been investigated, and whether SSD varies substantially among populations within bruchine species is poorly known...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725362/negative-correlation-between-altitudes-and-oxygen-isotope-ratios-of-seeds-exploring-its-applicability-to-assess-vertical-seed-dispersal
#20
Shoji Naoe, Ichiro Tayasu, Takashi Masaki, Shinsuke Koike
Vertical seed dispersal, which plays a key role in plant escape and/or expansion under climate change, was recently evaluated for the first time using negative correlation between altitudes and oxygen isotope ratio of seeds. Although this method is innovative, its applicability to other plants is unknown. To explore the applicability of the method, we regressed altitudes on δ(18)O of seeds of five woody species constituting three families in temperate forests in central Japan. Because climatic factors, including temperature and precipitation that influence δ(18)O of plant materials, demonstrate intensive seasonal fluctuation in the temperate zone, we also evaluated the effect of fruiting season of each species on δ(18)O of seeds using generalized linear mixed models (GLMM)...
October 2016: Ecology and Evolution
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