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https://www.readbyqxmd.com/read/29458122/regional-variations-of-cortical-bone-in-the-humeral-head-region-a-preliminary-study
#1
Yeming Wang, Jian Li, Jianhua Yang, Jingming Dong
BACKGROUND: Incidence of proximal humeral fractures dramatically increased over the last decade due to demographic changes. The goal of this study was to analyze regional characteristics of cortical bone in the humeral head region using cortical bone mapping (CBM) technique. METHODS: The proximal humerus of 103 healthy volunteers was imaged by clinical computed tomography (CT) scans. Three groups of volunteers were identified according to age: group A (20-39 years), group B (40-59 years), and group C (>60 years)...
February 16, 2018: Bone
https://www.readbyqxmd.com/read/29457360/neglected-areas-on-thorax-computed-tomography-evaluation-in-patients-with-chronic-obstructive-pulmonary-disease-paravertebral-muscles-and-para-aortic-adipose-tissue
#2
Mustafa Resorlu, Ozan Karatag, Canan A Toprak, Muhsin O Ozturk
INTRODUCTION: This study, investigated the para-aortic adipose tissue cross-sectional area, a novel predictor of cardiovascular diseases and degenerative changes in the paravertebral muscles, in patients with chronic obstructive pulmonary disease (COPD). METHOD: One hundred cases diagnosed as COPD and 50 healthy individuals with similar demographic characteristics were evaluated. Para-aortic adipose tissue cross-sectional area (mm2 ), subcutaneous adipose tissue thickness (mm), paravertebral muscle area (mm2 ) and fat deposition in muscle tissue were assessed radiologically...
February 18, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29456990/ketamine-versus-ketamine-magnesium-sulfate-for-procedural-sedation-and-analgesia-in-the-emergency-department-a-randomized-clinical-trial
#3
Reza Azizkhani, Azadeh Bahadori, Mohammadreza Shariati, Keyhan Golshani, Omid Ahmadi, Babak Masoumi
Background: The present study was designed to evaluate the effectiveness of magnesium sulfate (MgSO4 ) in procedural sedation and analgesia (PSA) when combined with ketamine in patients with fractures in emergency departments and required short and painful emergency procedures. Materials and Methods: In this study, 100 patients with fractures and dislocations who were presented to the emergency departments and required PSA for short and painful emergency procedures were randomly allocated to groups of ketamine plus MgSO4 or ketamine alone...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29456271/to-compare-is-to-despair-a-population-wide-study-of-neighborhood-composition-and-suicide-in-stockholm
#4
Kayuet Liu
Neighborhood context can change the effect of a socio-demographic attribute on the risk of suicide. Eight hypotheses about the interactions between neighborhood composition, ethnicity, income, and socially disadvantaged propositions are proposed based on social support, social comparison, and social regulation mechanisms. They are tested with a population-based dataset of all adults (1.4 million) who lived in the greater Stockholm area in the 1990s. On one hand, multilevel analysis shows that suicide risk increases with the level of affluence in one's neighborhood, particularly among individuals with low income...
November 1, 2017: Social Problems
https://www.readbyqxmd.com/read/29456219/descriptive-analysis-of-glomerulonephritis-by-histological-type-and-their-progression-among-adults-in-a-tertiary-care-center-in-sri-lanka
#5
Kawmadi W Gunawardena, Eranga S Wijewickrama, Carukshi Arambepola, Rushika D Lanerolle
Prevalence of different glomerulonephritides and their clinical course vary geographically. Our objectives are to assess the prevalence of different histological types of glomerulonephritis (GN) based on the light microscopic histology and to assess their progression according to histological type. A retrospective cross-sectional study was carried out among adult patients (>18 years) with a histological diagnosis of GN at the University Professorial Unit over a period of six months. Information including demographic data, renal biopsy findings, and progression of the disease through serum creatinine (SCr) level were collected through existing clinic records of consenting patients...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29455910/a-public-health-needs-assessment-for-domestic-indoor-overheating
#6
N Bundle, E O'Connell, N O'Connor, A Bone
OBJECTIVES: Indoor overheating is a potentially fatal health hazard that was identified as an issue requiring urgent action in the 2017 UK Climate Change Risk Assessment. We aimed to make research on this issue more accessible to local public health teams to encourage its inclusion in local strategic needs assessments. STUDY DESIGN: Epidemiological health needs assessment. METHODS: We adapted established health needs assessment methods, focussing on the epidemiological component, drawing evidence from a non-systematic literature review that was complemented by discussion with experts...
February 15, 2018: Public Health
https://www.readbyqxmd.com/read/29455750/trigger-events-and-poverty-transitions-among-young-adults-in-finland-after-leaving-the-parental-home
#7
Ilari Ilmakunnas
Studies have shown that leaving the parental home is associated with an increase in the risk of poverty. However, less is known about poverty dynamics after leaving the nest. Based on Finnish population register data, this research answers the question of how employment and demographic events affect poverty entries and exits among 18- to 24-year-olds in Finland. The follow-up of individuals starts when young adults move away from the parental home. In addition to descriptive methods, discrete-time event-history models are estimated...
February 2018: Social Science Research
https://www.readbyqxmd.com/read/29455690/effect-of-cerebral-perfusion-pressure-on-acute-respiratory-distress-syndrome
#8
Sonny Thiara, Donald E Griesdale, William R Henderson, Mypinder S Sekhon
BACKGROUND: Increased cerebral perfusion pressure (CPP)>70 mmHg has been associated with acute respiratory distress syndrome (ARDS) after traumatic brain injury (TBI). Since this reported association, significant changes in ventilation strategies and fluid management have been accepted as routine critical care. Recently, individualized perfusion targets using autoregulation monitoring suggest CPP titration>70 mmHg. Given these clinical advances, the association between ARDS and increased CPP requires further delineation...
February 19, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29455216/demographic-and-histopathological-patterns-of-neuro-epithelial-brain-tumors-in-eastern-province-of-saudi-arabia
#9
Mahmoud S Taha, Fahad M Almsned, Mohammed A Hassen, Ibrahim M Atean, Ahmed M Alwbari, Qasim K Alharbi, Marwah M Abdulkader, Husam S Almuhaish
OBJECTIVE: To review the demographic and pathological pattern of neuro-epithelial brain tumors in a tertiary referral center in the Eastern Province of Saudi Arabia and to compare the results of our study with other national and international studies. METHODS: This is a retrospective chart-review study of all patients with neuro-epithelial brain tumors referred and treated in our center between January 2010 and January 2015. The age, gender, tumor location, and histopathology were recorded...
January 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29454877/egyptian-and-jordanian-nurse-educators-perception-of-barriers-preventing-the-implementation-of-evidence-based-practice-a-cross-sectional-study
#10
Naglaa F A Youssef, Ali Alshraifeen, Karimeh Alnuaimi, Penney Upton
BACKGROUND: Studies discussing nurse educators' attitudes, knowledge/skills, practicing of evidence-based practice (EBP) and barriers encountered towards implementation is somewhat limited. OBJECTIVE: The study aimed to identify the attitudes, perceived knowledge/skills, and implementation of evidence-based as perceived by nurse educators, in Egyptian and Jordanian universities, and to assess factors preventing them from adopting it in nursing program. DESIGN/SETTING/RESPONDENTS/METHODS: A cross-sectional design was conducted including two groups from Egypt and Jordan...
February 10, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29454852/chronic-exposure-to-inhaled-traffic-related-nitrogen-dioxide-and-a-blunted-cortisol-response-in-adolescents
#11
Sam E Wing, Gretchen Bandoli, Donatello Telesca, Jason G Su, Beate Ritz
BACKGROUND: Chronic health effects of traffic-related air pollution, like nitrogen dioxide (NO2 ), are well-documented. Animal models suggested that NO2 exposures dysregulate cortisol function. OBJECTIVES: We evaluated the association between traffic-related NO2 exposure and adolescent human cortisol concentrations, utilizing measures of the cortisol diurnal slope. METHODS: 140 adolescents provided repeated salivary cortisol samples throughout one day...
February 15, 2018: Environmental Research
https://www.readbyqxmd.com/read/29454851/declines-in-adult-blood-lead-levels-in-new-york-city-compared-with-the-united-states-2004-2014
#12
Alexis Feinberg, Wendy McKelvey, Paromita Hore, Rania Kanchi, Patrick J Parsons, Christopher D Palmer, Lorna E Thorpe
OBJECTIVES: To assess changes in lead exposure in the New York City (NYC) adult population over a 10-year period and to contrast changes with national estimates, overall, and by socio-demographics and smoking status. METHODS: We used measurements of blood lead levels (BLLs) from NYC resident adults who participated in the NYC Health and Nutrition Examination Surveys (HANES) in 2004 and 2013-2014. We compared estimates of geometric means (GM), 95th percentiles, and prevalence of BLL ≥ 5 µg/dL overall and by subgroups over time, with adults who participated in the National HANES (NHANES) 2001-2004 and 2011-2014...
February 14, 2018: Environmental Research
https://www.readbyqxmd.com/read/29454804/physiological-predictors-of-leptin-vary-during-menses-and-ovulation-in-healthy-women
#13
Kristyn E Sylvia, Tierney K Lorenz, Julia R Heiman, Gregory E Demas
Although research has shown interactions between the reproductive system and energy homeostasis, it is not clear how environmental or behavioral factors may factor into these associations. Here we aimed to determine how changes in reproductive state (i.e., phase of the menstrual cycle) and other behavioral and physiological factors may influence leptin levels in healthy women, as well as how sexual activity may play a role in leptin modulation. We collected serum and saliva from 32 healthy women and measured leptin, estradiol, and progesterone...
February 14, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/29454590/understanding-how-prostate-cancer-patients-value-the-current-treatment-options-for-metastatic-castration-resistant-prostate-cancer
#14
Tarik Benidir, Karen Hersey, Antonio Finelli, Rob Hamilton, Anthony M Joshua, Girish Kulkarni, Alexandre Zlotta, Neil Fleshner
Several new compounds are now available for castration resistant prostate cancer (CRPC). Individual costs range between $40,000 and $93,000 with mean survival extensions from 2.4 to 4.8 months. Currently, it remains unclear how patients with prostate cancer (PCa) value the effect of these therapies in the setting of CRPC. OBJECTIVE: To assess patient understanding of core cancer concepts, opinions on the cost and overall benefit of CRPC drugs, whether out-of-pocket costs would change opinions and whether patients would ultimately opt out of CRPC drug treatment for an end-of-life (EOL) premium...
February 14, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29454513/outcomes-and-related-factors-in-a-cohort-of-infants-born-in-taiwan-over-a-period-of-five-years-2007-2011-with-borderline-viability
#15
Jui-Hsing Chang, Chyong-Hsin Hsu, Kao-Inn Tsou, Wai-Tim Jim
BACKGROUND: Advances in perinatal and neonatal care have increased the survival of extremely preterm infants, but the viability limit is still debated. Here we assess the survival, neonatal morbidity, and neurodevelopmental outcomes at 2 years of age of infants born at 22-26 weeks of gestation in Taiwan between 2007 and 2011. METHODS: This is a prospective longitudinal multicenter cohort study on extremely preterm infants registered in the Taiwan Premature Infant Developmental Collaborative Study Group from 2007 to 2011, including 22 neonatal care centers...
February 14, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29454478/usefulness-of-integrating-heart-failure-risk-factors-into-impairment-of-global-longitudinal-strain-to-predict-anthracycline-related-cardiac-dysfunction
#16
M Wesley Milks, Michael R Velez, Nishaki Mehta, Abiodun Ishola, Thomas Van Houten, Vedat O Yildiz, Raquel Reinbolt, Maryam Lustberg, Sakima A Smith, David A Orsinelli
The prediction of cancer therapeutics-related cardiac dysfunction (CTRCD) is an essential aspect of care for individuals who receive potentially cardiotoxic oncologic treatments. Certain clinical risk factors have been described for incident CTRCD, and measurement of left ventricular (LV) longitudinal strain by speckle tracking 2-dimensional echocardiography (2DE) is the best-validated myocardial mechanical imaging assessment to detect subtle changes in LV function during cancer treatment. However, the direct integration of clinical and imaging risk factors to predict CTRCD has not yet been extensively examined...
January 12, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29454342/social-support-for-patients-undergoing-liver-transplantation-in-a-public-university-hospital
#17
Clerison Stelvio Garcia, Agnaldo Soares Lima, Ehideé Isabel Gómez La-Rotta, Ilka de Fátima Santana Ferreira Boin
BACKGROUND: Several diseases may lead to the need for liver transplantation due to progressive organ damage until the onset of cirrhosis, resulting in changes in interpersonal relationships. Social Support for transplant candidates is an important variable, providing them with psychological and social well-being. This study aims to assess social support in chronic hepatic patients, waiting for liver transplantation. METHODS: A cross-sectional study was conducted with 119 patients, for convenience sampling, from the liver transplant waiting list at a Brazilian University Hospital Outpatients...
February 17, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29454135/short-term-outcomes-following-posterior-cervical-fusion-among-octogenarians-with-cervical-spondylotic-myelopathy-a-nsqip-database-analysis
#18
Caroline E Vonck, Joseph E Tanenbaum, Thomas T Bomberger, Edward C Benzel, Jason W Savage, Iain H Kalfas, Thomas E Mroz, Michael P Steinmetz
BACKGROUND: Context: Degenerative changes in the cervical spine occur in an age-dependent manner. As the U.S. population continues to age, the incidence of age-dependent, multi-level, degenerative cervical pathologies is expected to increase. Similarly, the average age of patients with cervical spondylotic myelopathy (CSM) will likely trend upward. Posterior cervical fusion (PCF) is often the treatment modality of choice in the management of multi-level cervical spine disease. Although outcomes following anterior cervical fusion for degenerative disease have been studied among older patients (aged 80 years and older), it is unknown if these results extend to octogenarian patients undergoing PCF for the surgical management of CSM...
February 14, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29453930/ensemble-survival-tree-models-to-reveal-pairwise-interactions-of-variables-with-time-to-events-outcomes-in-low-dimensional-setting
#19
Jean-Eudes Dazard, Hemant Ishwaran, Rajeev Mehlotra, Aaron Weinberg, Peter Zimmerman
Unraveling interactions among variables such as genetic, clinical, demographic and environmental factors is essential to understand the development of common and complex diseases. To increase the power to detect such variables interactions associated with clinical time-to-events outcomes, we borrowed established concepts from random survival forest (RSF) models. We introduce a novel RSF-based pairwise interaction estimator and derive a randomization method with bootstrap confidence intervals for inferring interaction significance...
February 17, 2018: Statistical Applications in Genetics and Molecular Biology
https://www.readbyqxmd.com/read/29453111/febrile-infection-related-epilepsy-syndrome-fires-therapeutic-complications-long-term-neurological-and-neuroimaging-follow-up
#20
Hsiu-Fen Lee, Ching-Shiang Chi
PURPOSE: To understand the long-term neurological outcomes and chronological changes of brain MRIs in patients with febrile infection-related epilepsy syndrome (FIRES). METHODS: From December 2000 to May 2016, 29 patients diagnosed with FIRES were collected retrospectively. The demographic distribution, clinical manifestations, neuroimaging findings, and treatment methodology were described. Follow-up clinical outcomes and chronological evolution of neuroimaging findings were analyzed...
February 6, 2018: Seizure: the Journal of the British Epilepsy Association
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