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https://www.readbyqxmd.com/read/28340377/possible-protective-effect-of-royal-jelly-against-cyclophosphamide-induced-prostatic-damage-in-male-albino-rats-a-biochemical-histological-and-immuno-histo-chemical-study
#1
Sara Mohammed Naguib Abdel-Hafez, Rehab Ahmed Rifaai, Walaa Yehia Abdelzaher
Almost all the chemotherapy treat many cancer types effectively, but it leads to severe side effects. Chemotherapy like cyclophosphamide (CP) not works only on the active cells, such as cancer cells, but also acts on the healthy cells. Royal jelly (RJ) was reported to have a lot of therapeutic effects besides being an anti-oxidant and anti-cancer agent. The purpose of this study was to assess the possible protective role of RJ in ameliorating the toxic effects of CP overdose in the rat prostatic tissue. The rats were separated into 4 groups; control group, RJ group, CP group and RJ with CP group...
March 21, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28336034/a-fumbled-handoff-to-inpatient-rehab
#2
(no author information available yet)
No abstract text is available yet for this article.
April 2017: AORN Journal
https://www.readbyqxmd.com/read/28317527/phototherapy-and-combination-therapies-for-vitiligo
#3
REVIEW
Samia Esmat, Rehab A Hegazy, Suzan Shalaby, Stephen Chu-Sung Hu, Cheng-Che E Lan
Vitiligo is a disease characterized by disappearance of melanocytes from the skin. It can negatively influence the physical appearance of affected individuals, and may profoundly affect a person's psychosocial function and quality of life. Therefore, vitiligo should not be considered as merely a condition that affects a patient's appearance, but needs to be actively treated in patients who seek medical help. Phototherapy has been used as the main treatment modality for patients with vitiligo. Different forms of phototherapy for vitiligo include broadband UVB, narrowband UVB, excimer light and excimer laser, and psoralen plus UVA...
April 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28302555/development-of-bioinformatics-infrastructure-for-genomics-research-in-h3africa
#4
Nicola J Mulder, Ezekiel Adebiyi, Marion Adebiyi, Seun Adeyemi, Azza Ahmed, Rehab Ahmed, Bola Akanle, Mohamed Alibi, Don L Armstrong, Shaun Aron, Efejiro Ashano, Shakuntala Baichoo, Alia Benkahla, David K Brown, Emile R Chimusa, Faisal M Fadlelmola, Dare Falola, Segun Fatumo, Kais Ghedira, Amel Ghouila, Scott Hazelhurst, Iunu Isewon, Segun Jung, Samar Kamal Kassim, Jonathan K Kayondo, Mamana Mbiyavanga, Ayton Meintjes, Somia Mohammed, Abayomi Mosaku, Ahmed Moussa, Mustafa Muhammd, Zahra Mungloo-Dilmohamud, Oyekanmi Nashiru, Trust Odia, Adaobi Okafor, Olaleye Oladipo, Victor Osamor, Jellili Oyelade, Khalid Sadki, Samson Pandam Salifu, Jumoke Soyemi, Sumir Panji, Fouzia Radouani, Oussama Souiai, Özlem Tastan Bishop
BACKGROUND: Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure. H3ABioNet, a pan-African bioinformatics network, was established to build capacity specifically to enable H3Africa (Human Heredity and Health in Africa) researchers to analyze their data in Africa. Since the inception of the H3Africa initiative, H3ABioNet's role has evolved in response to changing needs from the consortium and the African bioinformatics community...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28296777/interleukin-1%C3%AE-and-interleukin-1receptor-antagonist-polymorphisms-in-egyptian-children-with-febrile-seizures-a-case-control-study
#5
Salah Al Morshedy, Hosam F Elsaadany, Hany E Ibrahim, Ashraf M Sherif, Mohsen A A Farghaly, Mayy A N Allah, Heba Abouzeid, Shaimaa S A Elashkar, Mohammed E Hamed, Manar M Fathy, Atef M Khalil, Maha A Noah, Mohamed S Hegab, Ahmed R Ahmed, Mustafa I A Hashem, Ahmed A Emam, Heba G Anany, Boshra R Ibrahim, Heba H Gawish, Rehab M Nabil, Lobna Abdel Fattah, Salah F Alsayed
Febrile seizure is the most common seizure disorder of childhood. Of the pro-inflammatory cytokines, interleukin-1 is defined as the first endogenous pyrogen.We designed this study to investigate single-nucleotide polymorphisms (SNPs) situated at positions -31 (C/T), and -511 (C/T) of interleukin-1beta (IL-1β) gene promoter and interleukin-1receptor antagonist (IL-1RA) gene variable number of tandem repeats in intron 2 (VNTR); to determine whether these polymorphisms could be a marker of susceptibility to febrile seizures in Egyptian children and we also measured the serum level of IL-1β to assess its relation to such polymorphisms...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28286306/a-controlled-study-of-the-role-of-cryopreserved-amniotic-membrane-transplant-during-strabismus-reoperations
#6
Rehab Rashad Kassem, Ahmed Mostafa Kamal, Randa Mohamed Abdel-Moneim El-Mofty, Hala Mostafa Elhilali
PURPOSE: To evaluate the effects of using cryopreserved human amniotic membrane (AM) transplant during strabismus reoperations. METHODS: A total of 30 patients with persistent strabismus were included in this controlled, prospective study. Patients were divided into two groups of 15 patients each. The AM group underwent strabismus reoperation with wrapping of the muscles with cryopreserved amniotic membrane. Controls underwent strabismus reoperation without an AM wrap...
March 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28285121/a-novel-rehabilitation-intervention-for%C3%A2-older-patients-with-acute-decompensated%C3%A2-heart-failure-the-rehab-hf-pilot-study
#7
Gordon R Reeves, David J Whellan, Christopher M O'Connor, Pamela Duncan, Joel D Eggebeen, Timothy M Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J Patel, Dalane W Kitzman
OBJECTIVES: This study sought to assess a novel physical rehabilitation intervention in older patients hospitalized for acute decompensated heart failure (ADHF). BACKGROUND: After ADHF, older patients, who are frequently frail with multiple comorbidities, have prolonged and incomplete recovery of physical function and remain at high risk for poor outcomes. METHODS: The REHAB-HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) pilot study was a 3-site, randomized, attention-controlled pilot study of a tailored, progressive, multidomain physical rehabilitation intervention beginning in the hospital and continuing for 12 weeks post-discharge in patients ≥60 years hospitalized with ADHF...
March 5, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28279729/access-to-post-hospitalization-acute-care-facilities-is-associated-with-payer-status-for-open-abdominal-aortic-repair-and-open-lower-extremity-revascularization-in-the-vascular-quality-initiative
#8
Jesus G Ulloa, Karen Woo, Chi-Hong Tseng, Melinda Maggard-Gibbons, David Rigberg
OBJECTIVE: Uninsured patients may not have access to post-acute care facilities that play an important role in clinical recovery and functional outcomes after vascular surgery. We sought to determine whether discharge disposition is associated with insurance status. METHODS: We retrospectively reviewed data from the Vascular Quality Initiative(®) for patients who underwent open abdominal aortic repair (OAR), infra-inguinal bypass (IB) or supra-inguinal bypass (SB) between January 2012 and July 2015...
March 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28275859/gene-expression-of-mirna-138-and-cyclin-d1-in-oral-lichen-planus
#9
Noha A Ghallab, Rehab Fawzy Kasem, Safa Fathy Abd El-Ghani, Olfat G Shaker
OBJECTIVES: This study aimed to evaluate microRNA-138 (miR-138) gene expression and its target cyclin D1 (CCND1) gene and protein expression in oral lichen planus (OLP) mucosa in an attempt to investigate their possible roles in OLP immunopathogenesis. METHODS: Sixty oral biopsy specimens were harvested from 30 healthy subjects and 30 OLP patients, subdivided into reticular, atrophic, and erosive groups (n = 10 each). Samples were subjected to quantitative real-time polymerase chain reaction analysis for quantification of miR-138 and CCND1 relative gene expression and immunohistochemical analysis to determine CCND1 protein expression...
March 8, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28273427/genetic-variants-of-inf-%C3%AE-and-its-mrna-expression-and-inflammatory-parameters-in-vitiligo-pathogenesis
#10
Rehab Karam, Haidy Essam, Mohammed Khater
Although genetics plays an essential role in the pathogenesis of vitiligo, however, vitiligo pathogenesis is still unclear. Our aim was to investigate the role of IFN-γ expression and polymorphism in vitiligo susceptibility, and whether ICAM-1, TNF-α, and TNF-β play a role in vitiligo pathogenesis as important inflammatory parameters. Eighty-five vitiligo patients and ninety controls were investigated for IFN-γ gene expression by quantitative RT-PCR, genotyped for IFN-γ +874 T/A (rs2430561) and IFN-γ +2109A/G (rs1861494) gene polymorphisms by PCR-SSP and PCR-RFLP respectively...
March 8, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28268980/street-rehab-linking-accessibility-and-rehabilitation
#11
Catherine Holloway, Behzad Heravi, Giulia Barbareschi, Sarah Nicholson, Stephen Hailes
As part of the Accessible Routes from Crowdsourced Cloud Services project (ARCCS) we conducted a series of experiments using the ARCCS sensor to identify push style of wheelchair users. The aim of ARCCS is to make use of a set of well-calibrated sensors to establish a processing chain that then provides ground truth of known accuracy about location, the nature of the environment, and physiological effort. In this paper we focus on two classification problems 1) The push style employed by people as they push themselves and 2) Whether the person is being pushed by an attendant or pushing themselves (independent of push style)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267466/rehabilitation-therapy-in-older-acute-heart-failure-patients-rehab-hf-trial-design-and-rationale
#12
Gordon R Reeves, David J Whellan, Pamela Duncan, Christopher M O'Connor, Amy M Pastva, Joel D Eggebeen, Leigh Ann Hewston, Timothy M Morgan, Shelby D Reed, W Jack Rejeski, Robert J Mentz, Paul B Rosenberg, Dalane W Kitzman
BACKGROUND: Acute decompensated heart failure (ADHF) is a leading cause of hospitalization in older persons in the United States. Reduced physical function and frailty are major determinants of adverse outcomes in older patients with hospitalized ADHF. However, these are not addressed by current heart failure (HF) management strategies and there has been little study of exercise training in older, frail HF patients with recent ADHF. HYPOTHESIS: Targeting physical frailty with a multi-domain structured physical rehabilitation intervention will improve physical function and reduce adverse outcomes among older patients experiencing a HF hospitalization...
March 2017: American Heart Journal
https://www.readbyqxmd.com/read/28266775/bone-marrow-derived-mesenchymal-stem-cells-mitigate-caspase-3-and-8-hydroxy-proline-induced-via-%C3%AE-adrenergic-agonist-in-pulmonary-injured-rats
#13
Mai O Kadry, Rehab M Abdel-Megeed
Estimating the ability of bone marrow-derived mesenchymal stem cells (BM-MSCs) to alleviate pulmonary injury induced via isoproterenol (ISP). ISP was injected in a dose of (100 mg/kg, subcutaneously twice at an interval of 24 h). One month post BM-MSCs transplantation by intravenous injection, pulmonary oxidative stress was assessed, and Western blot analyses and histopathological investigations were conducted. Compared with the normal control group, BM-MSCs transplantation significantly decreased the expression of pulmonary anti-oxidative stress marker...
March 7, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28259552/the-patient-education-learning-and-coping-strategies-improves-adherence-in-cardiac-rehabilitation-lc-rehab-a-randomised-controlled-trial
#14
Vibeke Lynggaard, Claus Vinther Nielsen, Ann-Dorthe Zwisler, Rod S Taylor, Ole May
BACKGROUND: Despite proven benefits of cardiac rehabilitation (CR), adherence to CR remains suboptimal. This trial aimed to assess the impact of the patient education 'Learning and Coping Strategies' (LC) on patient adherence to an eight-week CR program. METHODS: 825 patients with ischaemic heart disease or heart failure were open label randomised to either the LC arm (LC plus CR) or the control arm (CR alone) across three hospital units in Denmark. Both arms received same amount of training and education hours...
February 21, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28257625/association-of-il-10-gene-polymorphisms-and-susceptibility-to-juvenile-idiopathic-arthritis-in-egyptian-children-and-adolescents-a-case-control-study
#15
Manar M Fathy, Hosam F Elsaadany, Yasser F Ali, Mohsen A A Farghaly, Mohammed E Hamed, Hany E Ibrahim, Maha A Noah, Mayy A N Allah, Shaimaa S A Elashkar, Nasser I Abdelsalam, Hind M Abdelrahman, Ahmed R Ahmed, Heba G Anany, Sanaa M Ismail, Boshra R Ibrahim, Nashwa M Al Azizi, Heba H Gawish, Ghada M Al-Akad, Rehab M Nabil, Dalia S Fahmy, Salah F Alsayed
BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children worldwide. Among anti-inflammatory cytokines, interleukin-10 (IL-10) is a key immunosuppressive cytokine involved in the pathogenesis of JIA. To date, only a few studies concerned the association of interleukin-10 gene polymorphisms with JIA. In this study, we aimed to investigate 3 cytokine single-nucleotide polymorphisms situated at positions -1082(G/A), -819(C/T), and -592(C/A) in the promoter region of the IL-10 gene to determine whether this polymorphism could be a marker of susceptibility to JIA in Egyptian children and adolescents...
January 17, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28256050/prevalence-of-acne-vulgaris-and-its-impact-of-the-quality-of-life-among-secondary-school-aged-adolescents-in-sohag-province-upper-egypt
#16
Mohammed Abu El-Hamd, Essam El-Din Abdel-Aziz Nada, Mohammed Abdel-Kareem Moustafa, Rehab Ahmed Mahboob-Allah
BACKGROUND: Acne vulgaris is the most common dermatological condition encountered in adolescents. AIM: It was to determine the prevalence of acne vulgaris and its impact of the quality of life among adolescents attending secondary schools in Sohag Province, Upper Egypt. PATIENTS AND METHODS: This was a cross-sectional study conducted in randomly selected governmental and technical secondary schools in Sohag Province, Upper Egypt. Approval was taken from the scientific research committee of Sohag Faculty of Medicine and also from Ministry of Education...
March 2, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28255261/validation-of-the-french-version-of-the-patterns-of-activity-measure-in-patients-with-chronic-musculoskeletal-pain
#17
Charles Benaim, Bertrand Léger, Philippe Vuistiner, François Luthi
Background. The "Patterns of Activity Measure" (POAM-P) is a self-administered questionnaire that assesses "avoidance", "pacing" and "overdoing" activity patterns in chronic pain patients. Objectives. To adapt the POAM-P to French ("POAM-P/F") and test its validity and reliability in Chronic Musculo-Skeletal Pain patients (CMSP). Methods. We followed the recommended procedure for translation of questionnaires. Five hundred and ninety five inpatients, admitted to a tertiary rehab center in the French-speaking part of Switzerland for chronic pain after orthopedic trauma, were included (sex ratio M/F = 4...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28236627/assessment-of-health-related-quality-of-life-in-egyptian-adolescents-with-type-1-diabetes-dempu-survey
#18
Mona Hassan, Noha Musa, Rehab Abdel Hai, Ashgan Fathy, Amany Ibrahim
BACKGROUND: Type 1 diabetes (T1D) is a serious chronic illness that imposes significant morbidity and mortality with a major impact on the quality of life (QoL) that became a core issue in diabetes care. Understanding the effect of diabetes on QoL is important for day-to-day clinical management and also for public health policy initiatives aiming at improving health outcomes for those with diabetes. The objective of the study was to assess the QoL in adolescents with T1D and assess the applicability of the use of the "Quality of Life for Youth" questionnaire at the Diabetes, Endocrine and Metabolism Pediatric Unit (DEMPU) clinic...
March 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28235624/design-of-novel-injectable-in-situ-forming-scaffolds-for-non-surgical-treatment-of-periapical-lesions-in-vitro-and-in-vivo-evaluation
#19
Rehab N Shamma, Nermeen A Elkasabgy, Azza A Mahmoud, Shaimaa I Gawdat, Mohamed M Kataia, Mohamed A Abdel Hamid
Periapical lesions are considered one of the common pathological conditions affecting alveolar bone. The primary focus of this study was to investigate the effectiveness of formulating an injectable in-situ forming scaffold-loaded with risedronate (bone resorption inhibitor) and with lornoxicam (anti-inflammatory drug) for the non-surgical treatment of periapical lesions. The scaffolds were prepared using solvent-induced phase inversion technique. Two insoluble copolymers were investigated namely; PLGA (ester-terminal) and PLGA-A (acid-terminal), additionally, SAIB was added as a high viscosity water-insoluble carrier...
February 21, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28235529/dexmedetomidine-decreases-the-required-amount-of-bupivacaine-for-ultrasound-guided-transversus-abdominis-plane-block-in-pediatrics-patients-a-randomized-study
#20
Rehab Abdel Raof, Shahira Ahmed El Metainy, Doaa Abou Alia, Moataza Abdel Wahab
BACKGROUND: The effect of dexmedetomidine on the potency of bupivacaine for transversus abdominis plane (TAP) block in pediatric patients has not been investigated. STUDY OBJECTIVE: The primary objective of this study was to assess the effectiveness of dexmedetomidine to decrease the concentration of bupivacaine needed for analgesia for ultrasound-guided TAP block in a pediatric patient undergoing hernia repair or hydrocelectomy. DESIGN: This is a randomized, double-blind, up-down, dose-finding study...
February 2017: Journal of Clinical Anesthesia
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