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https://www.readbyqxmd.com/read/29672398/evaluating-quality-metrics-and-cost-after-discharge-a-population-based-cohort-study-of-value-in-health-care-following-elective-major-vascular-surgery
#1
Charles de Mestral, Konrad Salata, Mohamad A Hussain, Ahmed Kayssi, Mohammed Al-Omran, Graham Roche-Nagle
BACKGROUND: Early readmission to hospital after surgery is an omnipresent quality metric across surgical fields. We sought to understand the relative importance of hospital readmission among all health services received after hospital discharge. OBJECTIVE: The aim of this study was to characterize 30-day postdischarge cost and risk of an emergency department (ED) visit, readmission, or death after hospitalization for elective major vascular surgery. METHODS: This is a population-based retrospective cohort study of patients who underwent elective major vascular surgery - carotid endarterectomy, EVAR, open AAA repair, bypass for lower extremity peripheral arterial disease - in Ontario, Canada, between 2004 and 2015...
April 18, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29669330/diabetes-self-management-a-key-for-better-health-related-quality-of-life-in-patients-with-diabetes
#2
Hanan E Badr, Maha Al-Khaledi, Hussah Al-Dousari, Shaikhah Al-Dhufairi, Taiba Al-Mousawi, Rehab Al-Azemi, Farah Al-Azimi
OBJECTIVE: This study was aimed at assessing health-related quality of life (HRQOL) among adult patients with diabetes attending primary health care diabetes clinics in Kuwait and to examine the factors associated with patients with the HRQOL of patients with diabetes. METHODS: This cross-sectional study was conducted among 503 patients with diabetes attending 26 primary healthcare diabetes clinics in Kuwait. A self-administered questionnaire on participants' socio-demographic and clinical characteristics, in addition to the Diabetes Self-Management Questionnaire (DSMQ) to assess patients' DSM was used...
April 17, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29668561/a-randomized-controlled-trial-comparing-nitazoxanide-plus-lactulose-with-lactulose-alone-in-treatment-of-overt-hepatic-encephalopathy
#3
Sherief Abd-Elsalam, Ferial El-Kalla, Nadia Elwan, Rehab Badawi, Nehad Hawash, Shaimaa Soliman, Samah Soliman, Walaa Elkhalawany, Mennat-Allah ElSawaf, Asem Elfert
BACKGROUND AND AIMS: Hepatic encephalopathy (HE) is a reversible spectrum of neuropsychiatric abnormalities associated with liver dysfunction. Lactulose is a nonabsorbable disaccharide presently used to treat HE. Nitazoxanide (NTZ) has a broad-spectrum activity against urease-producing bacteria, so it decreases ammonia production and is therefore expected to reverse the symptoms of HE. A previous pilot study on HE patients given NTZ and lactulose had encouraging results with regard to amelioration of the clinical picture...
April 17, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29668338/morphometric-and-ultrastructural-analysis-of-tramadol-effects-on-epididymis-an-experimental-study
#4
Abdalla Mohamed Attia, Ola Ahmed Bakry, Hossam Yassin, Naglaa Sarhan, Rehab Samaka, Nahla Gamal
The effect of tramadol addiction on epididymal structure was not investigated before. Therefore, this experimental study was carried out to investigate the effect of chronic tramadol use on the epididymal structure using light and electron microscopies. Thirty adult Wister Albino male rats were divided into two groups: control group (five rats) and tramadol-treated group (25 rats), which was further subdivided into five subgroups that received tramadol orally at 4.5, 9, 45, 90, and 135 mg/kg/day, respectively, for 18 weeks...
April 18, 2018: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29667153/supplemented-amino-acids-may-enhance-the-walking-recovery-of-elderly-subjects-after-hip-fracture-surgery
#5
Roberto Aquilani, Carlo Zuccarelli Ginetto, Carla Rutili, Pietro Pisano, Evasio Pasini, Eleonora Baldissarro, Manuela Verri, Federica Boschi
The purpose of this study was to investigate whether supplemented essential amino acids (EAAs) could enhance rehabilitation therapy (Rehab) for recovery of walking capacity in subjects after hip fracture surgery (HFS). Eighty-three elderly subjects with HFS (20 ± 11 days after acute trauma) were eligible for the study and randomized to receive Rehab only (Rehab; n = 27), Rehab + placebo (RP; n = 28) or Rehab + EAAs (RE 8 g/day; n = 28). The patients' walking capacity (m) was measured by 6-min walking distance (6MWD) at admission and at discharge (median 66 days after admission)...
April 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29660970/inflammation-and-rehabilitation-outcomes-in-patients-with-nontraumatic-intracranial-haemorrhage
#6
Mirella Boselli, Roberto Aquilani, Roberto Maestri, Maria Pia Achilli, Nadia Arrigoni, Evasio Pasini, Anna Maria Condino, Federica Boschi, Maurizia Dossena, Daniela Buonocore, Manuela Verri
BACKGROUND: Systemic inflammation and its impact on rehabilitation for patients with non-traumatic haemorrhagic injury (HBI) sequelae has not yet been adequately documented. OBJECTIVE AND METHODS: We therefore considered 31 patients with HBI, to determine the serum levels of inflammatory markers (C-Reactive Protein, CRP and or interleukine-6, IL-6) to establish their impact on functional status (Functional Independence Measure, FIM: 18 indicating the worst performance and 126, a normal score)...
April 7, 2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29656979/reducing-length-of-stay-does-not-increase-emergency-room-visits-or-readmissions-in-patients-undergoing-primary-hip-and-knee-arthroplasties
#7
Andrea H Stone, Leah Dunn, James H MacDonald, Paul J King
BACKGROUND: Total hip and total knee arthroplasty (total joint arthroplasty [TJA]) are 2 of the most common elective surgeries. Identifying which patients are at highest risk for emergency room (ER) visits or readmissions within 90 days of surgery and the reasons for return are crucial to formulate ways to decrease these visits and improve patient outcomes. METHODS: This is a retrospective review of a consecutive series of 7466 unilateral primary TJA performed from July 2013 to June 2017; any patients who had an ER visit or readmission in the first 90 days after surgery were identified, and a detailed chart review was performed...
March 27, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29655678/anti-inflammatory-and-antioxidant-activities-of-naringin-isolated-from-carissa-carandas-l-in-vitro-and-in-vivo-evidence
#8
Ahmed H El-Desoky, Rehab F Abdel-Rahman, Osama K Ahmed, Hossam S El-Beltagi, Masao Hattori
BACKGROUND: Carissa carandas L. is known in folk medicine for its anti-inflammatory and hepatoprotective activities. Meanwhile it is an evergreen shrub that constitutes a continuous source of leaves throughout the year. HYPOTHESIS/PURPOSE: The leaves of Carissa carandas L. may be rich in compounds that can be used as safe anti-inflammatory and antioxidant remedies. The combined antioxidant and anti-inflammatory activities provoked the study of the hepatoprotective effects...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29649611/predictors-of-adverse-discharge-disposition-in-adult-spinal-deformity-and-associated-costs
#9
Peter G Passias, Gregory W Poorman, Cole A Bortz, Rabia Qureshi, Bassel G Diebo, Justin C Paul, Samantha R Horn, Frank A Segreto, Alexandra Pyne, Cyrus M Jalai, Virginie Lafage, Shay Bess, Frank J Schwab, Hamid Hassanzadeh
BACKGROUND CONTEXT: With advances in the understanding of adult spinal deformity (ASD), more complex osteotomy and fusion techniques are being implemented with increasing frequency. Patients undergoing ASD corrections infrequently require extended acute care, longer inpatient stays, and are discharged to supervised care. Given the necessity of value-based health care, identification of clinical indicators for adverse discharge disposition in ASD surgeries is paramount. PURPOSE: On nationwide and surgeon-created databases, identify predictors of adverse discharge disposition after ASD surgeries and view corresponding differences in charges...
April 9, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29617006/relevance-of-b-lines-on-lung-ultrasound-in-volume-overload-and-pulmonary-congestion-clinical-correlations-and-outcomes-in-patients-on-hemodialysis
#10
Marc M Saad, Jeanne Kamal, Elias Moussaly, Boutros Karam, Wissam Mansour, Emad Gobran, Saqib Hussen Abbasi, Ahmed Mahgoub, Puja Singh, Ross Hardy, Devjani Das, Cara Brown, Monica Kapoor, Seleshi Demissie, Morton J Kleiner, Elie El Charabaty, Suzanne E El Sayegh
BACKGROUND: Volume overload in patients on hemodialysis (HD) is an independent risk factor for cardiovascular mortality. B-lines detected on lung ultrasound (BLUS) assess extravascular lung water. This raises interest in its utility for assessing volume status and cardiovascular outcomes. METHODS: End-stage renal disease patients on HD at the Island Rehab Center being older than 18 years were screened. Patients achieving their dry weight (DW) had a lung ultrasound in a supine position...
November 29, 2017: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29614890/novel-instantly-dispersible-nanocarrier-powder-system-idnps-for-intranasal-delivery-of-dapoxetine-hydrochloride-in-vitro-optimization-ex-vivo-permeation-studies-and-in-vivo-evaluation
#11
Shahinaze A Fouad, Rehab N Shamma, Emad B Basalious, Mohamed M El-Nabarawi, Saadi A Tayel
Dapoxetine (D) suffers from poor oral bioavailability (42%) due to extensive metabolism in the liver. The aim of this study was to enhance the bioavailability of D via preparing instantly-dispersible nanocarrier powder system (IDNPs) for intranasal delivery of D. IDNPs were prepared using the thin film hydration technique, followed by freeze-drying to obtain easily reconstituted powder providing rapid and ready method of administration. The produced nanocarrier systems were evaluated for drug content, entrapment efficiency percentage, particle size, polydispersity index, zeta potential and drug payload...
April 3, 2018: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/29605863/increased-tenascin-c-and-dkk1-in-vitiligo-possible-role-of-fibroblasts-in-acral-and-non-acral-disease
#12
Samia M Esmat, Heba H El Hadidi, Rehab A Hegazy, Heba I Gawdat, Amira M Tawdy, Marwa M Fawzy, Dalia M AbdelHalim, Omnia S Sultan, Olfat G Shaker
Recently, multiple culprits-in addition to melanocytes-have been implicated in the pathogenesis of vitiligo. Among those factors are fibroblasts. However, their exact role has not been clearly elucidated. The aim of the study was to evaluate the possible role played by fibroblasts in vitiligo via studying the expression Tenascin C and DKK1 in acral versus non-acral vitiligo lesions. This case-control study included 19 non-segmental vitiligo patients and ten controls. All patients were subjected to thorough clinical evaluation...
March 31, 2018: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29602154/the-association-of-il-33-and-foxp3-gene-polymorphisms-with-recurrent-pregnancy-loss-in-egyptian-women
#13
Haidy E Zidan, Rehab S Abdul-Maksoud, Hala E Mowafy, Walid S H Elsayed
Deregulated immunity is one of the most important factors implicated in recurrent pregnancy loss (RPL). The possible role of interleukin-33 (IL-33) and forkhead/winged helix transcription factor (Foxp3) in RPL have not been fully investigated. We aimed to evaluate IL-33 rs1929992 and Foxp3 rs2232365 single nucleotide polymorphisms (SNPs) and their serum levels in Egyptian RPL females. Blood samples were collected from 142 RPL patients and 123 women as healthy controls. IL-33 rs1929992 SNP was determined by polymerase chain reaction restriction fragment length polymorphism and Foxp3 rs2232365 SNP was determined using allele specific polymerase chain reaction...
March 27, 2018: Cytokine
https://www.readbyqxmd.com/read/29600229/epidemiology-of-liver-cancer-in-nile-delta-over-a-decade-a-single-center-study
#14
Sherief Abd-Elsalam, Nadia Elwan, Hanan Soliman, Dina Ziada, Walaa Elkhalawany, Marwa Salama, Nehad Hawash, Mona Arafa, Rehab Badawi, Walaa M Shehata, Haidy S Khalil, Nehal Elmashad
Background: In Egypt, there has been a remarkable increase in the proportion of hepatocellular carcinoma (HCC) among chronic liver diseases patients. This rising proportion may be explained by the increasing risk factors as hepatitis C virus (HCV) infection, hepatitis B virus (HBV) infection, improvement of the diagnostic tools of HCC as well as the extended survival among patients with cirrhosis to allow time for some of them to develop HCC. The aim of this study was to study the epidemiology of HCC in Nile delta over the last decade...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29582637/swallowing-exercises-will-they-really-help-head-and-neck-cancer-patients
#15
Karim Mashhour, Rehab Abdelkader, Labiba Abdelkader, Shaimaa El Hadary, Wedad Hashem
Purpose: The work was a comparative study, the aim of which is to evaluate the impact of swallowing exercises on swallowing problems among head and neck cancer patients (HNCPs) after CRT. Methods: The sample of 60 HNCPs was equally divided into control and study groups. The investigators met all patients 3 times (before, during and after CRT); swallowing ability was assessed using the Sydney Swallowing Questionnaire (SSQ). The University of Texas, MD Anderson Cancer Center Swallowing Exercise Protocol was explained and demonstrated by the investigators to the study group...
March 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29581890/recurrent-discitis-in-the-acute-rehab-setting-a-case-report
#16
Kunj Patel, Lauren Hutts, Stephen Porter, Zachary Fausel, Dale Strasser
Introduction: Discitis is an infection of the intervertebral disc space that can lead to paralysis, sepsis, epidural abscess, or other life-threatening complications if left untreated and may sometimes present with limited laboratory abnormalities to clue a diagnosis. Case presentation: We present a case of a 67-year-old female in an acute rehabilitation setting who had presenting symptoms of sudden unexplained back pain refractory to pain control. She had a previous history of discitis and multiple failed knee replacement surgeries secondary to MSSA infections...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29575794/morphological-and-biochemical-features-of-cerebellar-cortex-after-exposure-to-zinc-oxide-nanoparticles-possible-protective-role-of-curcumin
#17
Mona G Amer, Rehab A Karam
Zinc oxide nanoparticles (ZnONPs) are widely used in the last decades. So, Investigation of its neurotoxic effect is important. This work aimed to investigate the potential adverse effects of ZnONPs on rat's cerebellar cortex and the possible neuroprotective role of curcumin. Forty male albino rats were randomly divided into control and experimental groups. Twenty rats were injected with ZnONPs and ten of them previously received curcumin before ZnONPs then continued together for 28 days. At the end of the experiment, cerebellar tissue samples were prepared for histological, morphometric, immunohistochemical study and tissue levels of oxidative stress markers and cytokine analysis...
March 25, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29571880/pilot-trial-of-a-tele-rehab-intervention-to-improve-outcomes-after-stroke-in-ghana-a-feasibility-and-user-satisfaction-study
#18
Fred S Sarfo, Nathaniel Adusei, Michael Ampofo, Frank K Kpeme, Bruce Ovbiagele
BACKGROUND: Tele-rehabilitation after stroke holds promise for under-resourced settings, especially sub-Saharan Africa (SSA), with its immense stroke burden and severely limited physical therapy services. OBJECTIVE: To preliminarily assess the feasibility and outcomes of mobile technology-assisted physical therapy exercises for stroke survivors in Ghana. METHODS: We conducted a prospective, single arm, pre-post study involving 20 stroke survivors recruited from a tertiary medical center, who received a Smartphone with the 9zest Stroke App® to deliver individualized, goal-targeted 5-days-a-week exercise program that was remotely supervised by a tele-therapist for 12 weeks...
April 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29567429/design-synthesis-and-biological-evaluation-of-novel-1-3-4-trisubstituted-pyrazole-derivatives-as-potential-chemotherapeutic-agents-for-hepatocellular-carcinoma
#19
Marwa F Harras, Rehab Sabour
A series of novel 1,3,4-trisubstituted pyrazole derivatives were synthesized and evaluated for their cytotoxic activity against three different cancer cell lines namely HCT116, UO-31 and HepG2. Compounds 3b, 3d, 7b and 9 showed excellent anticancer activity against all the tested cancer cell lines and had better cytotoxic activities than the reference drug, Sorafenib. Therefore, these compounds were chosen to be further evaluated in a panel of HCC cell lines. Among them, 3b and 7b were the most active compounds against HCC cells used here...
March 16, 2018: Bioorganic Chemistry
https://www.readbyqxmd.com/read/29560141/maternal-fetal-rhesus-rh-factor-incompatibility-in-arar-northern-saudi-arabia
#20
Raghad Mubarak Aljuhaysh, Nagah Mohamed Abo El-Fetoh, Malak Ibrahim Alanazi, Afaf Shuaib Albaqawi, Wafa Mohammed Alanazi, Najah Salah Alanazi, Reham Muqbil Alanazi, Atheer Mutab Alanazi, Eiman Mohammad Alnemer, Rahma Abdulhadi Alenezi, Tasleem Khoudier Alabdullatif, Rehab Abdallah Alanazi, Samiyah Sarhan Alanazi, Kawthar Saeed Alsultan, Ibtisam Matan Alanazi, Duaa Sami Alsunayni
Background and aim: Rh isoimmunization still contributes to the neonatal morbidity and mortality due to non-immunization, under-immunization, and in rare cases, false Rh typing. The main objective of this study was to determine the prevalence of Rh incompatibility, mothers' knowledge about Rh incompatibility, mothers' knowledge about anti-D immunoglobulin and to show the pregnancy outcome of Rh negative mothers. Methods: A cross-sectional study was carried out at the Maternity and Children Hospital in Arar city from November 2016 to May 2017...
December 2017: Electronic Physician
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