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https://www.readbyqxmd.com/read/29902941/accessibility-information-in-new-delhi-for-easenaccess-android-based-app-for-persons-with-disability-an-observational-study
#1
Yashovardhan Agarwal
BACKGROUND: The World Health Organization and the World Bank's "World Report on Disability" reported that over 1 billion people have various kinds of disability worldwide while Indian Census 2011 reported about 26 million in India. The United Nations Convention states, "The Rights of Persons with Disabilities (PwD) include accessibility to Information, Transportation, Environment, Communication Technology and Services". OBJECTIVE: This article takes forward the reason of making the "EasenAccess" (EnA) Android-based app to empower PwD with wheelchair-accessibility information, communication sentences and sending SOS signals with location...
June 14, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29884415/age-and-localization-dependent-functional-and-psychosocial-impairments-and-health-related-quality-of-life-six-months-after-oscc-therapy
#2
Sabine S Linsen, Nils-Claudius Gellrich, Gertrud Krüskemper
OBJECTIVES: The aim of the current study was to evaluate the functional and psychosocial impacts and changes in overall quality of life (QoL) following oral squamous cell carcinoma (OSCC) therapy in different age groups and in different oral locations. MATERIALS AND METHODS: The study assessed questionnaire responses from patients with OSCC (n = 1319) after 6 months of oncologic therapy, as collected in the DÖSAK Rehab Study. Oncological variables, dental status, sensory, QoL, psychosocial outcomes and coping strategies in younger (45-60 years) and older (61-100 years) patients were assessed for different OSCC locations including the entire oral cavity, maxilla, mandible and others besides the maxilla and mandible...
June 2018: Oral Oncology
https://www.readbyqxmd.com/read/29864979/detection-of-systemic-inflammation-in-severely-impaired-chronic-pain-patients-and-effects-of-a-cbt-act-based-multi-modal-pain-rehabilitation-program
#3
E-B Hysing, L Smith, M Thulin, R Karlsten, T Gordh
Aims A few previous studies indicate an ongoing of low-grade systemic inflammation in chronic pain patients (CPP) [1, 2]. In the present study we investigated the plasma inflammatory profile in severely impaired chronic pain patients. In addition we studied if there were any alterations in inflammation patterns at one-year follow up, after the patients had taken part in a CBT-ACT based 4 weeks in-hospital pain rehabilitation program (PRP). Methods Blood samples were collected from 52 well characterized chronic pain patients...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29862871/clinical-and-dermoscopic-evaluation-of-combined-salicylic-acid-20-and-azelaic-acid-20-versus-trichloroacetic-acid-25-chemical-peel-in-acne-a-rct
#4
Rania Abdel Hay, Rehab Hegazy, Mohamed Abdel Hady, Noha Saleh
BACKGROUND: Combined azelaic acid (AA) and salicylic acid (SA) has not been previously used for acne. OBJECTIVE: To compare the efficacy of this combination versus trichloroacetic acid (TCA) 25% peel in acne. METHODS: 34 patients were included in this trial. Patients received four sessions two-weeks apart. The combined solution was applied to one side of the face while TCA was applied to the other. Our outcomes were physician-reported clinical improvement, dermoscopic assessment of the erythema and patient's satisfaction...
June 4, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29862557/role-of-ppar-%C3%AE-agonist-fenofibrate-in-the-treatment-of-induced-benign-prostatic-hyperplasia-with-dysplastic-changes-in-rats
#5
Marwa M M Refaie, Rehab A Rifaai, Nagwa M Zenhom
Nearly all men who reach average life expectancy have prostate disease. The most common is benign prostatic hyperplasia (BPH). Peroxisome proliferator activated receptor alpha (PPARα) had protective effect in different models but still there are no studies explain its role in BPH. So that we investigated the effect of fenofibrate (FEN) on induced BPH by testosterone propionate (TP) (3 mg/kg/day for 4 weeks) subcutaneous injection followed by FEN (300 mg/kg/day) was given orally for 4 weeks. We measured prostate weights changes, prostatic tissue superoxide dismutase (SOD) and malondialdehyde (MDA) levels...
June 3, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29860632/circulating-irisin-and-chemerin-levels-as-predictors-of-seizure-control-in-children-with-idiopathic-epilepsy
#6
Marwa Elhady, Eman R Youness, Heba S Gafar, Ali Abdel Aziz, Rehab S I Mostafa
Irisin and chemerin peptides expression are triggered by hypoxia and involved in activation of inflammatory cascades in various organs including the brain; however, their role in epilepsy is not fully illustrated. This study aims to explore the predictive role of irisin and chemerin for seizure control in children with idiopathic epilepsy. This cross-sectional comparative study included 50 children with idiopathic epilepsy; 25 of them had controlled seizures over the previous 6 months and 30 age- and sex-matched healthy children as controls...
June 2, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29859774/media-evaluation-for-production-and-expansion-of-anti-cd19-chimeric-antigen-receptor-t-cells
#7
Rehab Alnabhan, Ahmed Gaballa, Lisa-Mari Mörk, Jonas Mattsson, Michael Uhlin, Isabelle Magalhaes
BACKGROUND: The use of CD19 chimeric antigen receptor (CAR) T cells to treat B-cell malignancies has proven beneficial. Several groups use serum to produce CD19 CAR T cells. Today, ready-to-use serum-free media that require no addition of serum are commercially available. Therefore, it becomes important to evaluate the production of CD19 CAR T cells with and without the addition of serum. METHODS: T cells from buffy coats were cultured in AIM-V and TexMACS (TM) supplemented with 5% human serum (A5% and TM5%, respectively), and in TM without serum...
May 30, 2018: Cytotherapy
https://www.readbyqxmd.com/read/29850285/ticagrelor-as-an-alternative-for-clopidogrel-associated-acute-arthritis
#8
Starr-Mar'ee C Bedy, Jacob P Kesterson, Greg Flaker
A 65-year-old Caucasian man was hospitalized for a non-ST-elevation myocardial infarction. On discharge, the patient was started on multiple new medications, including clopidogrel and atorvastatin. Twenty-six days after discharge, he presented to the Emergency Department (ED) with polyarthralgias. He was instructed to stop atorvastatin and to follow up with rheumatology and cardiology clinic. At cardiology clinic follow-up 43 days after ED discharge, clopidogrel was discontinued and patient was switched to ticagrelor...
2018: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/29807774/sending-our-lungs-to-rehab-the-future-of-ex-vivo-lung-perfusion
#9
EDITORIAL
Pablo Sanchez, Jonathan D'Cunha
No abstract text is available yet for this article.
April 16, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29795076/use-of-outpatient-rehabilitation-among-adult-stroke-survivors-20-states-and-the-district-of-columbia-2013-and-four-states-2015
#10
Carma Ayala, Jing Fang, Cecily Luncheon, Sallyann Coleman King, Tiffany Chang, Matthew Ritchey, Fleetwood Loustalot
Stroke is a leading cause of mortality and disability in the United States (1,2). Approximately 800,000 American adults experience a stroke each year (2,3). Currently, approximately 6 million stroke survivors live in the United States (2). Participation in stroke rehabilitation (rehab), which occurs in diverse settings (i.e., in-hospital, postacute care, and outpatient settings), has been determined to reduce stroke recurrence and improve functional outcomes and quality of life (3,4). Despite longstanding national guidelines recommending stroke rehab, it remains underutilized, especially in the outpatient setting...
May 25, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29788192/initial-assessment-of-the-risk-assessment-and-prediction-tool-in-a-heterogeneous-neurosurgical-patient-population
#11
Matthew Piazza, Nikhil Sharma, Benjamin Osiemo, Scott McClintock, Emily Missimer, Diana Gardiner, Eileen Maloney, Danielle Callahan, J Lachlan Smith, William Welch, James Schuster, M Sean Grady, Neil R Malhotra
BACKGROUND: Bundled care payments are increasingly being explored for neurosurgical interventions. In this setting, skilled nursing facility (SNF) is less desirable from a cost perspective than discharge to home, underscoring the need for better preoperative prediction of postoperative disposition. OBJECTIVE: To assess the capability of the Risk Assessment and Prediction Tool (RAPT) and other preoperative variables to determine expected disposition prior to surgery in a heterogeneous neurosurgical cohort, through observational study...
May 21, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29787960/late-presentation-of-ectopia-vesica-with-malignant-transformation-a-case-report-and-review
#12
Sami Eldirdiri, Rehab M Elmushly, Sami G Elazhary
INTRODUCTION: Exstrophy of the bladder is a rare congenital anomaly usually treated in neonatal or childhood period. When combined with renal agenesis and presents for the first time in the adulthood with malignant transformation, is an extreme rarity. CASE PRESENTATION: We present a case of 65 years single male who presented with a right irreducible inguinal hernia and an unreconstructed Ectopia Vesicae with fungating tumor. He was anemic with impaired renal function, left renal agenesis and right sided hydronephrosis, hydroureter and distal ureteric stricture...
May 10, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29787786/preparation-of-99m-tc-levetiracetam-intranasal-microemulsion-as-the-first-radiotracer-for-spect-imaging-of-the-synaptic-vesicle-protein-sv2a
#13
Hassan M Rashed, Rehab N Shamma, Hanan A El-Sabagh
Selective receptors imaging using gamma emitting radiopharmaceuticals allows accurate diagnosis and follow up of many brain related disorders. Levetiracetam, a selective SV2A receptor antiepileptic, was successfully radiolabeled using 99m Tc. Different conditions affecting the labelling process were studied and optimum radiochemical yield of 89.8% was obtained. 99m Tc-levetiracetam was effectively formulated and characterized as microemulsion with particle size of 16.34 ± 5.58 nm and polydispersity index of 0...
May 19, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29785894/developmental-and-molecular-responses-of-buffalo-bubalus-bubalis-cumulus-oocyte-complex-matured-in-vitro-under-heat-shock-conditions
#14
Ashraf El-Sayed, Rehab Nagy, Amal K El-Asheeri, Liala N Eid
SummaryTo investigate the effects of physiologically relevant heat shock during oocyte maturation, buffalo cumulus-oocyte complexes (COCs) were cultured at 38.5°C (control) or were exposed to 39.5°C (T1) or 40.5°C (T2) for the first 6 h of in vitro maturation (IVM), followed by 38.5°C through the next 18 h/IVM and early embryonic development up to the blastocyst stage. Gene expression analysis was performed on selected target genes (HSF-1, HSF-2, HSP-70, HSP-90, BAX, p53, SOD1, COX1, MAPK14) in denuded oocytes and their isolated cumulus cells resulting from control COCs as well as from COCs exposed to a temperature of 39...
May 22, 2018: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/29783942/effect-of-the-patient-education-learning-and-coping-strategies-in-cardiac-rehabilitation-on-return-to-work-at-one-year-a-randomised-controlled-trial-show-lc-rehab
#15
Birgitte Laier Bitsch, Claus Vinther Nielsen, Christina Malmose Stapelfeldt, Vibeke Lynggaard
BACKGROUND: Personal resources are identified as important for the ability to return to work (RTW) for patients with ischaemic heart disease (IHD) or heart failure (HF) undergoing cardiac rehabilitation (CR). The patient education 'Learning and Coping' (LC) addresses personal resources through a pedagogical approach. This trial aimed to assess effect of adding LC strategies in CR compared to standard CR measured on RTW status at one-year follow-up after CR. METHODS: In an open parallel randomised controlled trial, patients with IHD or HF were block-randomised in a 1:1 ratio to the LC arm (LC plus CR) or the control arm (CR alone) across three Danish hospital units...
May 21, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29782981/cationic-starch-safe-and-economic-harvesting-flocculant-for-microalgal-biomass-and-inhibiting-e-coli-growth
#16
Mehrez E E El-Naggar, Farag A Samhan, Abeer A A Salama, Rehab M Hamdy, Gamila H Ali
Cationized starch-based flocculation processes are the subject of increasing attention because of their non-toxicity, biodegradability and relatively low price synthesized. The study aimed to evaluate the flocculability of different cationic starches using different concentrations of glycidyltrimethylammonium chloride (GTAC) with different degree of substitution (DS) ranged from 0.13 to 0.57. Cationized starch were characterized using Fourier Transform Infrared (FTIR), scanning electron microscopy (SEM) and toxicity checked using experimental animal procedure...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29774765/-staying-safe-a-narrative-review-of-falls-prevention-in-people-with-parkinson-s-pdsafe
#17
Sophia Hulbert, Lynn Rochester, Alice Nieuwboer, Vicki Goodwin, Carolyn Fitton, Kim Chivers-Seymour, Ann Ashburn
BACKGROUND: Parkinson's disease demonstrates a spectrum of motor and non-motor symptoms. Falling is common and disabling. Current medical management shows minimal impact to reduce falls or fall-related risk factors, such as deficits in gait, strength, and postural instability. Despite evidence supporting rehabilitation in reducing fall risk factors, the most appropriate intervention to reduce overall fall rate remains inconclusive. This article aims to 1) synthesise current evidence and conceptual models of falls rehabilitation in Parkinson's in a narrative review; and based on this evidence, 2) introduce the treatment protocol used in the falls prevention and multi-centre clinical trial "PDSAFE"...
May 18, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29774156/pilot-study-of-orphenadrine-as-a-novel-treatment-for-muscle-cramps-in-patients-with-liver-cirrhosis
#18
Sherief Abd-Elsalam, Ferial El-Kalla, Lobna A Ali, Samah Mosaad, Walaa Alkhalawany, Berihan Elemary, Rehab Badawi, Asmaa Elzeftawy, Amr Hanafy, Asem Elfert
Background and aims: Muscle cramps markedly affect the quality of life in cirrhotic patients with no available highly effective treatment. The aim of this study was to assess the safety and efficacy of orphenadrine in the treatment of muscle cramps in cirrhotic patients. Methods: The study enrolled 30 liver cirrhosis patients complaining of frequent muscle cramps (≥3 per week), who were randomized to receive either orphenadrine 100 mg or calcium carbonate 500 mg twice daily as a control for one month...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29772939/enabling-appropriate-personnel-skill-mix-for-progressive-realization-of-equitable-access-to-assistive-technology
#19
Emma M Smith, Rosemary Joan Gowran, Hasheem Mannan, Brian Donnelly, Liliana Alvarez, Diane Bell, Silvana Contepomi, Liezel Ennion Wegner, Evert-Jan Hoogerwerf, Tracey Howe, Yih-Kuen Jan, Jeanne Kagwiza, Natasha Layton, Ritchard Ledgerd, Malcolm MacLachlan, Giulia Oggero, Cecilia Pettersson, Thais Pousada, Elsje Scheffler, Sam Wu
BACKGROUND AND METHODS: This paper reviews the current capacity of personnel in enabling access to assistive technology (AT) as well as the systems and processes within which they work, and was reviewed, discussed, and refined during and following the Global Research, Innovation, and Education in Assistive Technology (GREAT) Summit. FINDINGS: Key concepts addressed include a person-centred team approach; sustainability indicators to monitor, measure, and respond to needs for service design and delivery; education, research, and training for competent practice, using the six rehab-workforce challenges framework; and credentialing frameworks...
May 17, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29766017/outcomes-according-to-discharge-location-for-persons-who-inject-drugs-receiving-outpatient-parenteral-antimicrobial-therapy
#20
Helen T D'Couto, Gregory K Robbins, Kevin L Ard, Sarah E Wakeman, Justin Alves, Sandra B Nelson
Background: Opioid use disorder poses a significant public health risk. Persons who inject drugs (PWID) suffer from high mortality and morbidity secondary to serious infectious diseases, often requiring prolonged courses of outpatient parenteral antibiotics. The goal of this study was to determine the outcomes of PWID discharged to home or to a skilled nursing or rehabilitation facility (SNF/rehab) with parenteral antibiotic treatment under an outpatient parenteral antimicrobial therapy (OPAT) program...
May 2018: Open Forum Infectious Diseases
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