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Urinary stone disease

Ines van Dooren, Kenn Foubert, Sebastiaan Bijttebier, Mart Theunis, Stefaniya Velichkova, Magda Claeys, Luc Pieters, Vassiliki Exarchou, Sandra Apers
Stone diseases present a major health problem in the Western society, since both urinary and biliary stones occur with a relatively high prevalence of 10-12 % and 10-20 %, respectively, and demonstrate a high recurrence rate. At the moment treatment is mainly based on interventional procedures, or prophylactic and dissolution therapy. However, many of the current drugs cause severe side effects, and therefore, there is an increasing interest in natural medicines. At the moment no registered herbal medicinal products are available for treatment of gallstones...
October 24, 2016: Planta Medica
Mehmet Erol Yıldırım, Metin Canbal, Ekrem Ozyuvali, Ömer Faruk Karataş
OBJECTIVE: Urinary tract conditions have been an important part of diseases from antiquity until today. Historically, many plants and herbs have been used for the treatment of urinary disorders. METHODS: Celâlüddîn Hızır bin Ali el-Konevi (Hadji Pasha) is one of the most famous physician who lived in Anatolia between 13th and 14th centuries. He has written one of the most important medical books of that era, "Müntehab-ıŞifa" (solution of wellness) in Turkish...
September 2016: Avicenna Journal of Phytomedicine
Joel E Abbott, Roger L Sur
The aim of this paper was to evaluate the current technology and designs of flexible ureterorenoscopes. We will review contemporary fiberoptic and digital ureteroscopes, including a discussion on ureteroscope damage and repair, and lastly present the projected future of flexible ureterorenoscopy. Ureterorenoscopy has evolved dramatically over the past several decades, which has led to landscape reshaping of stone disease treatment and upper tract pathology. Advancements in tip control, miniaturization of scopes, introduction of a digital chip on the tip, disposable devices to augment surgery, surgical experience/familiarity and most recently single use scopes are all independent factors that have increased flexible ureterorenoscopy adoption and success...
October 19, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Helena Chang, David T Tzou, Manint Usawachintachit, Brian D Duty, Ryan S Hsi, Jonathan D Harper, Mathew D Sorensen, Marshall Stoller, Roger L Sur, Thomas Chi
<b>Objectives</b>: Registry-based clinical research in nephrolithiasis is critical to advancing quality in urinary stone disease management and ultimately reducing stone recurrence. A need exists to develop HIPAA-compliant registries comprised of integrated electronic health record (EHR) data using prospectively defined variables. An EHR-based standardized patient database - The Registry for Stones of the Kidney & Ureter (ReSKU™) was developed and herein we describe our implementation outcomes...
October 19, 2016: Journal of Endourology
Cigdem Donmez, Ece Konac, Batuhan T Aydogan, Cenk Y Bilen
PURPOSE: To study whether -160 C > A (rs16260) and -347 G > GA (rs5030625) single nucleotide polymorphisms of the regulatory region (rSNPs) of CDH1 gene modulate the risk of nephrolithiasis. METHODS: Genomic DNA of 101 patients with calcium oxalate nephrolithiasis and 114 healthy controls were screened for both polymorphisms, using polymerase chain reaction-restriction fragments length polymorphism method (PCR-RLFP). Haplotype frequencies were also analyzed...
2016: SpringerPlus
David T Tzou, Manint Usawachintachit, Kazumi Taguchi, Thomas Chi
Ultrasound has become a mainstay tool in urologists' armamentarium for the diagnosis and management of nephrolithiasis. From starting as a rudimentary form of imaging, it has come to play a more prominent role over time, paralleling evolution in ultrasound technology. Throughout the medical community there is a growing emphasis on reducing the amount of ionizing radiation delivered to patients during routine imaging. As such there has been a resurgence of interest in ultrasound given its lack of associated radiation exposure and proven effectiveness as a diagnostic and therapeutic imaging modality...
October 12, 2016: Journal of Endourology
Raiz Ahmad Misgar, Parvez Mohiuddin Dar, Shariq Rashid Masoodi, Munir Ahmad, Khursheed Alam Wani, Arshad Iqbal Wani, Mir Iftikhar Bashir
BACKGROUND: Although primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the West, in India, PHPT is still an uncommonly diagnosed, overtly symptomatic disease with skeletal, muscular, and renal manifestations. AIMS: To describe the profile and surgical outcome of 78 consecutive PHPT patients over a period of two decades at a single center. MATERIALS AND METHODS: All patients who underwent evaluation and surgery for PHPT from January 1996 to December 2015 were included...
September 2016: Indian Journal of Endocrinology and Metabolism
Jian Guo Wen, Xin Jian Liu, Zhi Min Wang, Tian Fang Li, Mark L Wahlqvist
The melamine contaminated milk powder contamination scandal occurred in China in 2008. Its main consequences so far have been urinary stone formation in children with associated renal damage and increased child mortality. Eight years have passed, but food safety issues still remain of concern in the daily lives of millions of Chinese. Vigilance is required to ensure no recurrence of such food safety problems. Ongoing studies focus on the early detection of food industry malpractice, mechanisms whereby these toxic substances induce disease and how its advent may be prevented and better managed...
December 2016: Asia Pacific Journal of Clinical Nutrition
D Bazin, E Letavernier, J-P Haymann, P Méria, M Daudon
INTRODUCTION: The presence of pathological calcifications, which can be either concretions or ectopic call for physicochemical characterisation techniques in order to define a significant diagnosis. The aim of this review is to present a set of characterisation techniques able to describe at the micrometer scale their structural and chemical characteristics and show their place at the hospital. METHOD: Results already published in the last ten years based on characterisation techniques present in laboratories or specific to large-scale instruments are presented...
September 21, 2016: Progrès en Urologie
Xingsheng Li, Melissa L Ellis, Alexander E Dowell, Ranjit Kumar, Casey D Morrow, Trenton R Schoeb, John Knight
: Colonization with Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stone disease. To improve our limited understanding of host/O.formigenes and microbe/O.formigenes interactions, germ-free or altered Schaedler flora (ASF) mice were colonized with O.formigenes Germ-free mice were stably colonized with O.formigenes suggesting O.formigenes does not require other organisms to sustain its survival. Examination of intestinal material indicated no viable O.formigenes in the small intestine, ∼4 × 10(6) O...
September 23, 2016: Applied and Environmental Microbiology
Ozay Demiray, Erdem Cevik, Ferhat Cuce
BACKGROUND: Complete blood count (CBC) parameters may associated with multiple diseases. Urinary stone disease is common public problem. Predictive value of CBC parameters may be associated with urinary stone disease. OBJECTIVES: To analyze the association between complete blood count (CBC) parameters and urinary stone disease. PATIENTS AND METHODS: This study was a retrospective observational study of 3,099 patients who were admitted to the urology outpatient clinic or diagnosed with urinary stone disease in the emergency services department...
July 2016: Iranian Red Crescent Medical Journal
Robert A Goldfarb, Yunhua Fan, Stephanie Jarosek, Sean P Elliott
PURPOSE: Ureteral obstruction in cervical cancer occurs in up to 11% of patients, many of whom undergo ureteral stenting. Our aim was to describe the patient burden of chronic ureteral stenting in a population-based cohort by detailing two objectives: (1) the frequency of repeat procedures for ureteral obstruction; and, (2) the frequency of urinary adverse effects (UAEs) (e.g., lower urinary tract symptoms, flank pain). MATERIALS AND METHODS: From SEER-Medicare, we identified 202 women who underwent ureteral stent placement prior to or following cervical cancer treatment...
September 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
A Neisius, C Thomas, F C Roos, W Jäger, I Tsaur, G Bartsch, T Knoll, A Haferkamp
BACKGROUND: Urolithiasis is a widespread disease. Diagnostic imaging plays an important role in the evaluation and management of patients with suspected urolithiasis. Furthermore, modern imaging methods may provide information on stone location, size, fragility and composition aiding the urologist to determine the appropriate treatment modality. PURPOSE: Based on the current literature and guidelines, this review reports on the various new and established diagnostic imaging modalities...
October 2016: Der Urologe. Ausg. A
Erkin Serdaroglu, Mahfuz Aydogan, Kadriye Ozdemir, Mustafa Bak
BACKGROUND: Urolithiasis (UL) is a common problem in pediatric nephrology practice. About 9-23% of all pediatric UL cases consist of patients under 1 years old. The aim of the present study was to determine etiologic causes, clinical features and short term prognosis of urolithiasis in the first two years of life. METHODS: Two-hundred children between 0-2 years of age (mean age 10.3±6.1 months) with urolithiasis were included to the study. All children were completely evaluated for urolithiasis etiology...
September 13, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Kleiton G R Yamaçake, Giovanni S Marchini, Sabrina Reis, Alexandre Danilovic, Fábio C Vicentini, Fábio C M Torricelli, Miguel Srougi, Eduardo Mazzucchi
PURPOSE: To compare the clinical, metabolic, and calculi characteristics of cystine and struvite stone patients after percutaneous nephrolithotripsy (PCNL). MATERIAL AND METHODS: Between January/2006-July/2013, 11 cystine stone patients were treated in our clinic. Of those, 3 were excluded due to incomplete follow-up. Eight cystine stone patients (2 with bilateral disease; 10 renal units-RU) were considered for further analysis. A cohort of 8 struvite stone formers (10RU) was matched having the same age, gender, body mass index (BMI) and Guys stone score...
September 1, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Fabio C M Torricelli, Manoj Monga, Vinicius Dall'Aqua, Giovanni S Marchini, Fabio C Vicentini, Alexandre Danilovic, Miguel Srougi, Eduardo Mazzucchi
OBJECTIVE: To compare the outcomes of percutaneous nephrolithotomy (PCNL) in immunocompromised patients with those of PCNL in healthy population. PATIENTS AND METHODS: A matched case-control study was performed from January 2009 through December 2014 using our prospectively collected kidney stone database. Patients with positive serology to human immunodeficiency virus (HIV), hepatitis C (cellular immune dysfunction), and patients on high dose of immunosuppressive drugs for treatment of autoimmune diseases composed the case group...
October 5, 2016: Journal of Endourology
Patricia Funes, Gloria Echagüe, Irene Ruiz, Lourdes Rivas, Jorge Zenteno, Rosa Guillén
UNLABELLED: The lithogenic risk profile is a graphical representation of metabolic factors and urinary saturation involved in the stone formation with their respective critical values. AIM: To determine the lithogenic risk profile in patients with urolithiasis. MATERIAL AND METHODS: Personal data such as anthropometric, history of diseases and family history of urolithiasis were recorded. Different compounds acting as promoters or inhibitors of crystallization were measured in serum and urine samples, and the data obtained were used to calculate urinary saturation using Equil software...
June 2016: Revista Médica de Chile
Shifa Narula, Simran Tandon, Shrawan Kumar Singh, Chanderdeep Tandon
AIMS: Kidney stone formation is a highly prevalent disease, affecting 8-10% of the human population worldwide. Proteins are the major constituents of human kidney stone's organic matrix and considered to play critical role in the pathogenesis of disease but their mechanism of modulation still needs to be explicated. Therefore, in this study we investigated the effect of human kidney stone matrix proteins on the calcium oxalate monohydrate (COM) mediated cellular injury. MAIN METHODS: The renal epithelial cells (MDCK) were exposed to 200μg/ml COM crystals to induce injury...
September 1, 2016: Life Sciences
Richard J Chaytor, Krishnamoorthy Rajbabu, Paul A Jones, Liam McKnight
OBJECTIVES: This study will evaluate the accuracy of Dual-energy CT (DECT) to characterise urinary tract stone composition on patients presenting to a UK hospital with renal colic. The study will also assess the additional radiation dose burden of DECT over standard protocol. METHODS: Data from 106 DECTs between October 2011 and October 2015 were retrospectively analysed. Patients were imaged using a Toshiba Aquilion ONE™ CT scanner. All patients received a low-dose non-contrast CT of the abdomen and pelvis prior to a stone-targeted DECT at 80 and 135 peak kilovoltages and 40mm field of view...
September 2, 2016: British Journal of Radiology
Juan-Pablo Caballero-Romeu, Alberto Budia-Alba, Juan-Antonio Galan-Llopis, Maria-Dolores Montoya-Lirola, Pedro-José García-Tabar, Juan-Francisco Galiano-Baena, Nuria Albertos-Mira-Marcelí, Jeronimo Gonzalvez-Piñera
BACKGROUND: Urinary stones disease is becoming more common not only in adults but also in children. Most cases are resolved with extracorporeal shock wave lithotripsy, but miniaturization of endoscopes has increased the use of ureteroscopy in resolving ureteral stones, most notably in children. CASE PRESENTATION: This presentation focuses on two cases of microureteroscopy. In both cases, the presence of lithiasis in the pelvic ureter was suspected to be the cause of ureter hydronephrosis, and a microureteroscopy was performed for treatment purposes...
2016: J Endourol Case Rep
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