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Adolescent breast

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https://www.readbyqxmd.com/read/29346353/the-burden-of-cancer-in-25-29-year-olds-in-new-zealand-a-case-for-a-wider-adolescent-and-young-adult-age-range
#1
Kirsten R Ballantine, Victoria Utley, Heidi Watson, Michael J Sullivan, Ruth Spearing
AIMS: New Zealand currently defines the adolescent and young adult (AYA) group for cancer services as young people 12-24 years of age, while other countries favour a designation of 15-29 years. This study was undertaken to compare cancer incidence and survival among 25-29 year olds to New Zealand's younger AYA population and to assess survival for our 15-29 year population against international benchmarks. METHODS: Diagnostic and demographic information for cancer registrations between 2000 and 2009 for 25-29 year olds was obtained from the New Zealand Cancer Registry...
January 19, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29327114/anthropometric-characteristics-and-ovarian-cancer-risk-and-survival
#2
Albina N Minlikeeva, Kirsten B Moysich, Paul C Mayor, John L Etter, Rikki A Cannioto, Roberta B Ness, Kristen Starbuck, Robert P Edwards, Brahm H Segal, Sashikant Lele, Kunle Odunsi, Brenda Diergaarde, Francesmary Modugno
PURPOSE: Multiple studies have examined the role of anthropometric characteristics in ovarian cancer risk and survival; however, their results have been conflicting. We investigated the associations between weight change, height and height change and risk and outcome of ovarian cancer using data from a large population-based case-control study. METHODS: Data from 699 ovarian cancer cases and 1,802 controls who participated in the HOPE study were included. We used unconditional logistic regression adjusted for age, race, number of pregnancies, use of oral contraceptives, and family history of breast or ovarian cancer to examine the associations between self-reported height and weight and height change with ovarian cancer risk...
January 11, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29287287/-breast-reduction-surgery-as-an-example-of-surgery-on-demand-in-adolescents
#3
Johannes C Bruck, Anna-Kristine Wipper
Surgical options to optimise one's body image are also accessible to adolescents. Although the vast majority of surgical procedures in this group of patients focus on otoplasty, 4 % of procedures in Germany are performed on the breast. The onset of menarche has not changed much in recent years, but obesity seems to generate problems with the breast for young girls. Since it is difficult to assess maturity and psychological resilience in young patients, a plastic surgeon is faced with an area of conflicts regarding his or her will to meet patients' reasonable wishes to ease their suffering, offer reliable and sustainable results, and comply with legal regulations that are largely uncertain...
December 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29277402/early-nutrition-influences-developmental-myelination-and-cognition-in-infants-and-young-children
#4
Sean Deoni, Douglas Dean, Sarah Joelson, Jonathan O'Regan, Nora Schneider
Throughout early neurodevelopment, myelination helps provide the foundation for brain connectivity and supports the emergence of cognitive and behavioural functioning. Early life nutrition is an important and modifiable factor that can shape myelination and, consequently, cognitive outcomes. Differences in the nutritional composition between human breast and formula milk may help explain the functional and cognitive disparity often observed between exclusively breast versus formula-fed children. However, past cognitive and brain imaging studies comparing breast and formula feeding are often: cross-sectional; performed in older children and adolescents relying on parental recall of infant feeding; and generally treat formula-fed children as a single group despite the variability between formula compositions...
December 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/29273649/epidemiology-of-cancers-in-lahore-pakistan-among-children-adolescents-and-adults-2010-2012-a-cross-sectional-study-part-2
#5
Farhana Badar, Shahid Mahmood
OBJECTIVES: To estimate the cancer incidence by age group for the Lahore district population within the Punjab Cancer Registry (PCR), Pakistan. The average annual population of Lahore was 9.8 million in 2010-2012. This is a sequel to a study published earlier. DESIGN: A cross-sectional study. SETTING: The registry has 19 centres in Lahore reporting their data to the coordinating office located within the Shaukat Khanum Memorial Cancer Hospital and Research Center (SKMCH&RC), Lahore, Pakistan...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29235933/faster-ticking-rate-of-the-epigenetic-clock-is-associated-with-faster-pubertal-development-in-girls
#6
Alexandra M Binder, Camila Corvalan, Verónica Mericq, Ana Pereira, José Luis Santos, Steve Horvath, John Shepherd, Karin B Michels
Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a predictor of health. Pubertal timing has similarly been associated with cancer risk and mortality rate among females. We examined the association between AgeAccel and pubertal timing and adolescent breast composition in the longitudinal Growth and Obesity Cohort Study. AgeAccel was estimated in whole blood using the Horvath method at breast Tanner 2 (B2) and 4 (B4)...
December 13, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/29232668/revised-reference-values-for-the-intake-of-sodium-and-chloride
#7
Daniela Strohm, Angela Bechthold, Sabine Ellinger, Eva Leschik-Bonnet, Peter Stehle, Helmut Heseker
BACKGROUND: In January 2017, the nutrition societies of -Germany, Austria and Switzerland revised the reference values for sodium and chloride intake. METHODS: For adults, the estimated value for sodium intake was derived on the basis of a balance study. The estimated values for children and adolescents were extrapolated from this estimated value considering differences in body mass. For infants aged 0 to under 4 months, an estimated value was set based on the sodium intake via breast milk...
December 12, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29228880/a-recurrence-of-bilateral-diffuse-sclerosing-lobular-hyperplasia-of-breast-a-case-report
#8
Osama Elfituri, Snehal Sonawane, Haoliang Xu, Michael A Warso, Elizabeth Wiley
Mammary sclerosing lobular hyperplasia is an uncommon benign fibroproliferative lesion of adolescent and young women, often of African American heritage with an incidence of ~3%. Patients generally complain of a palpable, painless, or slightly tender and well-defined lump in breast. Very rarely, this lesion may be bilateral and diffuse. The definitive diagnosis of sclerosing lobular hyperplasia requires histopathologic evaluation. Here, we describe a case of diffuse sclerosing lobular hyperplasia in a 29-year-old African American woman that required bilateral mastectomy and recurred bilaterally requiring second resections...
December 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29205296/impact-of-latency-time-on-survival-for-adolescents-and-young-adults-with-a-second-primary-malignancy
#9
Melanie Goldfarb, Aaron S Rosenberg, Qian Li, Theresa H M Keegan
BACKGROUND: The adverse impact of second primary malignancies (SPMs) on survival is substantial for adolescents and young adults (AYAs; ie, those 15-39 years old). No studies have evaluated whether the latency time between the first malignancy (the primary malignancy [PM]) and the SPM affects cancer-specific survival (CSS). METHODS: A multivariate Cox proportional hazards regression with Surveillance, Epidemiology, and End Results data for 13 regions from 1992 to 2008 was used to ascertain whether the latency time (1-5 vs ≥ 6 years) to the development of an SPM affected the CSS and overall survival with respect to either the PM or SPM for AYAs with common SPMs...
December 4, 2017: Cancer
https://www.readbyqxmd.com/read/29194591/a-mutational-comparison-of-adult-and-adolescent-and-young-adult-aya-colon-cancer
#10
James V Tricoli, Lisa A Boardman, Rajesh Patidar, Sivasish Sindiri, Jin S Jang, William D Walsh, Paul M McGregor, Corinne E Camalier, Michele G Mehaffey, Wayne L Furman, Armita Bahrami, P Mickey Williams, Chih-Jian Lih, Barbara A Conley, Javed Khan
BACKGROUND: It is possible that the relative lack of progress in treatment outcomes among adolescent and young adult (AYA) patients with cancer is caused by a difference in disease biology compared with the corresponding diseases in younger and older individuals. There is evidence that colon cancer is more aggressive and has a poorer prognosis in AYA patients than in older adult patients. METHODS: To further understand the molecular basis for this difference, whole-exome sequencing was conducted on a cohort of 30 adult, 30 AYA, and 2 pediatric colon cancers...
November 30, 2017: Cancer
https://www.readbyqxmd.com/read/29187144/non-alcoholic-fatty-liver-disease-and-its-associations-among-adolescents-in-an-urban-sri-lankan-community
#11
Shaman Rajindrajith, Arunasalam Pathmeswaran, Chamilka Jayasinghe, Dulani Kottahachchi, Anuradhani Kasturiratne, Shamila T de Silva, Madunil A Niriella, Anuradha S Dassanayake, Arjuna P de Silva, H Janaka de Silva
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a common problem across the world. We aimed to determine the prevalence of NAFLD and its associations in Sri Lankan adolescents living in an urban Sri Lankan community. METHOD: The study population consisted of the birth cohort of the year 2000, residing in the Ragama Medical Officer of Health area. Socio-demographic and anthropometric data [anthropometric measurements, blood pressure and total body fat distribution] of these adolescents were collected by trained data collectors...
November 29, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29187016/adolescent-female-with-turner-s-syndrome-and-46-x-der-y-del-y-p11-2-del-q11-2-karyotype-with-gonadoblastoma-and-dysgerminoma
#12
Barenya Mukerji, Eli Balshan, Robert Haderer, Wendy Shertz, Robert Graebe
Gonadal dysgenesis patients with Y chromosomal material are subject to increased risk for germ cell tumors. We report a case of an adolescent female presenting with Turner-like syndrome with primary amenorrhea and Tanner stage 1 breast development. Karyotype showed one X chromosome and a minute pericentromeric fragment of Y chromosome without any functional Y genes in all the cells, unlike a mosaic pattern, represented as 46,X,der(Y)del(Y)(p11.2)del(q11.2). Laparoscopic bilateral gonadectomy was performed due to presence of Y chromosome material and histopathology confirmed gonadoblastoma with a focus of dysgerminoma of the right ovary...
November 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29184806/polycystic-ovary-syndrome-in-adolescence-diagnostic-and-therapeutic-strategies
#13
REVIEW
Manmohan K Kamboj, Andrea E Bonny
Controversy continues about the underlying etiopathogenesis, diagnostic criteria, and recommendations for polycystic ovary syndrome (PCOS) in adolescents. Recent literature has recognized these deficiencies and evidence based expert recommendations have become more available. The purpose of this chapter is to offer primary care providers a practical understanding and approach to the diagnosis and treatment of PCOS in adolescents. Although the presence of polycystic ovary morphology (PCOM) is included as a key diagnostic criterion of PCOS in adults, it is currently not recommended for the diagnosis in adolescents...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29169075/maternal-intention-to-exclusively-breast-feed-among-mainland-chinese-mothers-a-cross-sectional-study
#14
Xiao Yang, Wan-Yim Ip, Ling-Ling Gao
OBJECTIVE: to examine postpartum maternal recall of their intentions to exclusively breast feed among breastfeeding women and identify its predictors. DESIGN AND SETTING: a cross-sectional descriptive study was conducted in a regional teaching hospital at Guangzhou, China between April 1 and July 14, 2014. PARTICIPANTS: 571 mothers who were within four days after delivery were recruited to the study. MEASUREMENTS: data were collected by four research assistants with maternal intention to breast feed data sheet, the Network Support for Breastfeeding Scale (NSBS), and a socio-demographic data sheet...
November 10, 2017: Midwifery
https://www.readbyqxmd.com/read/29162146/smoking-and-risk-of-breast-cancer-in-the-generations-study-cohort
#15
Michael E Jones, Minouk J Schoemaker, Lauren B Wright, Alan Ashworth, Anthony J Swerdlow
BACKGROUND: Plausible biological reasons exist regarding why smoking could affect breast cancer risk, but epidemiological evidence is inconsistent. METHODS: We used serial questionnaire information from the Generations Study cohort (United Kingdom) to estimate HRs for breast cancer in relation to smoking adjusted for potentially confounding factors, including alcohol intake. RESULTS: Among 102,927 women recruited 2003-2013, with an average of 7...
November 22, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/29142203/mode-of-delivery-and-child-and-adolescent-psychological-well-being-evidence-from-hong-kong-s-children-of-1997-birth-cohort
#16
Cherry Y Leung, Gabriel M Leung, C Mary Schooling
Mode of delivery (vaginal or cesarean section) is thought to affect gut microbiota, which in turn may affect psychological well-being. As such, mode of delivery is potentially a modifiable factor for psychological well-being. Here we examined the association of mode of delivery with child and adolescent psychological well-being. We used multivariable linear regression in a population-representative Hong Kong Chinese birth cohort, "Children of 1997," to examine the adjusted associations of mode of delivery with behavioral problems assessed from parent-reported Rutter score at ~7 (n = 6294) and ~11 years (n = 5598), self-esteem assessed from self-reported Culture-Free Self-Esteem Inventory score at ~11 years (n = 6937) and depressive symptoms assessed from self-reported Patient Health Questionnaire-9 score at ~13 years (n = 5797)...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29139615/breast-education-for-schoolgirls-why-what-when-and-how
#17
Nicola Brown, Jenny Smith, Amanda Brasher, Debbie Risius, Anna Marczyk, Joanna Wakefield-Scurr
Schools are fundamental settings for health education and adolescent females are an important group for promoting positive breast habits. We surveyed 2089 schoolgirls (11-18 years) to provide evidence for, and guidance on, breast education for schoolgirls. 26% reported negative feelings about their breasts and 87% reported ≥ one breast concern. 72% wanted to know more about breast cancer (69% rating this extremely important). >50% wanted to know more about breast sag and breast pain. Preferred delivery format was age eleven (50%), girls only taught sessions (41%) with female teachers (43%)...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29139584/large-pseudoangiomatous-stromal-hyperplasia-of-the-breast-in-adolescent-patient
#18
Treskova Inka, Vicari Pavel, Karnos Vaclav, Ruzicka Lukas, Mukensnabl Petr, Slunecko Robert, Kydlicek Tomas
No abstract text is available yet for this article.
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29128819/the-saw-tooth-operation-for-giant-fibroadenomas
#19
Vijay Naraynsingh, Lemuel Pran, Shariful Islam, Shamir Cawich
Fibroadenomas are the most common benign breast lesions affecting adolescents and young women. Cosmesis is an important factor when considering surgical management for these masses. Giant fibroadenomas (>5cm), because of their size, may require larger incisions resulting in significant scarring and scar complications in these young women. Several approaches have been employed, usually involving large incisions, when performing a lumpectomy for giant fibroadenomas. In this report, we highlight a new technique for removal of these masses, which allows the removal of large fibroadenomas through a relatively small, cosmetically acceptable, circumareolar incision...
November 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29118296/mismatch-between-fetal-sexing-and-birth-phenotype-a%C3%A2-case-of-complete-androgen-insensitivity-syndrome
#20
Keisuke Yoshii, Yasuhiro Naiki, Yumiko Terada, Maki Fukami, Reiko Horikawa
With advancing maternal age, the number of prenatal genetic tests is increasing in many countries. Prenatal genetic tests, such as amniocentesis, chorionic villus sampling and non-invasive prenatal testing, can disclose fetal chromosomal sex, although these tests were originally designed to prenatally diagnose chromosomal aneuploidies, such as trisomy 21, 18 and 13. Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive disorder caused by an androgen receptor dysfunction leading to hormone resistance...
November 9, 2017: Endocrine Journal
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