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https://www.readbyqxmd.com/read/29142203/mode-of-delivery-and-child-and-adolescent-psychological-well-being-evidence-from-hong-kong-s-children-of-1997-birth-cohort
#1
Cherry Y Leung, Gabriel M Leung, C Mary Schooling
Mode of delivery (vaginal or cesarean section) is thought to affect gut microbiota, which in turn may affect psychological well-being. As such, mode of delivery is potentially a modifiable factor for psychological well-being. Here we examined the association of mode of delivery with child and adolescent psychological well-being. We used multivariable linear regression in a population-representative Hong Kong Chinese birth cohort, "Children of 1997," to examine the adjusted associations of mode of delivery with behavioral problems assessed from parent-reported Rutter score at ~7 (n = 6294) and ~11 years (n = 5598), self-esteem assessed from self-reported Culture-Free Self-Esteem Inventory score at ~11 years (n = 6937) and depressive symptoms assessed from self-reported Patient Health Questionnaire-9 score at ~13 years (n = 5797)...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29139615/breast-education-for-schoolgirls-why-what-when-and-how
#2
Nicola Brown, Jenny Smith, Amanda Brasher, Debbie Risius, Anna Marczyk, Joanna Wakefield-Scurr
Schools are fundamental settings for health education and adolescent females are an important group for promoting positive breast habits. We surveyed 2089 schoolgirls (11-18 years) to provide evidence for, and guidance on, breast education for schoolgirls. 26% reported negative feelings about their breasts and 87% reported ≥ one breast concern. 72% wanted to know more about breast cancer (69% rating this extremely important). >50% wanted to know more about breast sag and breast pain. Preferred delivery format was age eleven (50%), girls only taught sessions (41%) with female teachers (43%)...
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29139584/large-pseudoangiomatous-stromal-hyperplasia-of-the-breast-in-adolescent-patient
#3
Treskova Inka, Vicari Pavel, Karnos Vaclav, Ruzicka Lukas, Mukensnabl Petr, Slunecko Robert, Kydlicek Tomas
No abstract text is available yet for this article.
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29128819/the-saw-tooth-operation-for-giant-fibroadenomas
#4
Vijay Naraynsingh, Lemuel Pran, Shariful Islam, Shamir Cawich
Fibroadenomas are the most common benign breast lesions affecting adolescents and young women. Cosmesis is an important factor when considering surgical management for these masses. Giant fibroadenomas (>5cm), because of their size, may require larger incisions resulting in significant scarring and scar complications in these young women. Several approaches have been employed, usually involving large incisions, when performing a lumpectomy for giant fibroadenomas. In this report, we highlight a new technique for removal of these masses, which allows the removal of large fibroadenomas through a relatively small, cosmetically acceptable, circumareolar incision...
November 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29118296/mismatch-between-fetal-sexing-and-birth-phenotype-a%C3%A2-case-of-complete-androgen-insensitivity-syndrome
#5
Keisuke Yoshii, Yasuhiro Naiki, Yumiko Terada, Maki Fukami, Reiko Horikawa
With advancing maternal age, the number of prenatal genetic tests is increasing in many countries. Prenatal genetic tests, such as amniocentesis, chorionic villus sampling and non-invasive prenatal testing, can disclose fetal chromosomal sex, although these tests were originally designed to prenatally diagnose chromosomal aneuploidies, such as trisomy 21, 18 and 13. Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive disorder caused by an androgen receptor dysfunction leading to hormone resistance...
November 9, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29111259/cancer-incidence-and-mortality-among-young-adults-aged-20-39-years-worldwide-in-2012-a-population-based-study
#6
Miranda M Fidler, Sumit Gupta, Isabelle Soerjomataram, Jacques Ferlay, Eva Steliarova-Foucher, Freddie Bray
BACKGROUND: To date, the burden of cancer among young adults has rarely been studied in depth. Our aim was to describe the scale and profile of cancer incidence and mortality worldwide among 20-39 year-olds, highlighting major patterns by age, sex, development level, and geographical region. METHODS: We did a population-based study to quantify the burden of young adult cancers worldwide. We defined young adult cancers as those occurring between the ages of 20 and 39 years because these individuals will have passed puberty and adolescence, but not yet experienced the effects of hormonal decline, immune response deterioration, or organ dysfunction associated with chronic health conditions...
October 27, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29108166/information-for-the-adolescent-woman-and-her-parents-abortion-and-the-risk-of-breast-cancer
#7
(no author information available yet)
Studies from many nations suggest that induced abortion (IA) may be a causal risk factor for the development of breast cancer. Researchers agree that IA contributes to the increased risk of breast cancer by delaying the timing of a full-term pregnancy which is a protective factor. Increasing numbers of studies now show that IA prior to 32 weeks in and of itself is a risk factor for breast cancer due to the physiology of breast development and the manner in which abortion interferes with the maturation of the breast cells...
2017: Issues in Law & Medicine
https://www.readbyqxmd.com/read/29104587/notch-and-its-oncogenic-activity-in-human-malignancies
#8
REVIEW
Marlena Brzozowa-Zasada, Adam Piecuch, Marek Michalski, Oliwia Segiet, Józef Kurek, Marzena Harabin-Słowińska, Romuald Wojnicz
Background: Increasing evidence has demonstrated that Notch signaling is deregulated in human hematological malignancies and solid tumors. This signaling has a protumorigenic effect but may also act as a tumor suppressor. How induction of a single pathway gives rise to the opposite effects in different cell types is still unknown. Methods: This review article includes available data from peer-reviewed publications associated with the role of Notch signaling during cancer pathogenesis...
2017: European Surgery: ACA: Acta Chirurgica Austriaca
https://www.readbyqxmd.com/read/29099545/evaluation-of-the-body-parts-that-preoccupy-adolescents-with-body-dysmorphic-disorder
#9
Mohammad Jafferany, Ferdnand C Osuagwu
Objective: To evaluate which body parts preoccupy adolescents with body dysmorphic disorder (BDD). Methods: Patients admitted to an inpatient psychiatric hospital who agreed to take part in the study completed the Body Dysmorphic Disorder Questionnaire (child and adolescent version) and Body Dysmorphic Disorder Diagnostic Module. Patients also completed a questionnaire that addressed age at onset, coping strategies, history of sexual abuse, amount of time patients spent thinking about their perceived defects, and the area of the body that the participants were preoccupied with and the specific coping strategy used...
October 26, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29082436/adolescent-young-adults-aya-with-cancer-seeking-integrative-oncology-consultations-demographics-characteristics-and-self-reported-outcomes
#10
Gabriel Lopez, Wenli Liu, Kevin Madden, Bryan Fellman, Yisheng Li, Eduardo Bruera
PURPOSE: Integrative Oncology (IO) consultations offer cancer patients counseling regarding complementary integrative medicine (CIM). We explored the CIM interests and symptom burden of AYA cancer patients presenting for an IO consultation. METHODS: Patients referred for an IO physician consultation at an academic medical center from September 1, 2009 to December 31, 2013 completed an assessment on presentation: MYCaW, ESAS (10 symptoms, 0-10, 10 worst possible), CIM use survey, and SF-12 QOL survey...
October 29, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29078121/cancer-in-adolescents-and-young-adults-national-incidence-and-characteristics-in-japan
#11
Izumi Inoue, Fumiaki Nakamura, Kimikazu Matsumoto, Tetsuya Takimoto, Takahiro Higashi
OBJECTIVE: Adolescents and young adults (AYA) with cancer are confronted with unique challenges in areas of paramount concern within their age group, such as fertility, education, career, and delayed and long-term effects of treatment. However, the extent and depth of the problem has never been examined in the Japanese population. The aim of this study was to describe the status of cancer patients in the AYA population, using data from the hospital-based cancer registry (HBCR). STUDY DESIGN: Patients included in the HBCR from January 2011 to December 2014 were included in this study to evaluate the incidence and cancer distribution trends among AYA...
October 24, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29067280/charcot-marie-tooth-hereditary-neuropathy-revealed-after-administration-of-docetaxel-in-advanced-breast-cancer
#12
Hampig Raphael Kourie, Nicolas Mavroudakis, Philippe Aftimos, Martine Piccart
Charcot-Marie-Tooth (CMT) neuropathy is the most common hereditary cause of neuropathy. Diagnosis is usually not made during the childhood but in adolescence or late adulthood. It is reported in the literature that some neurotoxic chemotherapeutical agents can reveal an asymptomatic CMT IA hereditary neuropathy. To our knowledge, we report here the first case of CMT IA revealed in a 55-year-old woman after the administration of docetaxel/trastuzumab/pertuzumab for metastatic breast cancer. This case stresses again the necessity to obtain a complete personal and familial anamnesis and to perform a neurologic examination before the administration of neurotoxic chemotherapeutical agents to prevent the clinical expression of these hereditary neuropathies...
October 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29066061/reduction-mammoplasty-in-adolescents-and-elderly-a-ten-year-case-series-analyzing-age-related-outcome-with-focus-on-safety-and-complications
#13
Anna E Wirthmann, Lena Welsch, Sascha V Wellenbrock, Lara Kasper, Torsten Schlosshauer, Ahmet Bozkurt, Susanne Hüttinger, Ulrich M Rieger
INTRODUCTION: Reduction mammoplasty alleviates symptoms of macromastia in various ways. Current study results mainly identify perioperative risk factors for middle aged patients. We investigated a large series of consecutive breast reductions procedures to study whether patients' age at the time of operation is related to the postoperative outcome. METHODS: We retrospectively reviewed all non-oncologic breast reduction procedures at a single institution over a ten year time period, analyzing patients (age, BMI, comorbidities, medication) and operation specific characteristics' (pedicle, nipple-to-sternal notch, resection weight, complications) to identify risk factors related to patients' age at the time of operation...
September 28, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29058178/developmental-exposure-to-the-ssri-citalopram-causes-long-lasting-behavioural-effects-in-the-three-spined-stickleback-gasterosteus-aculeatus
#14
M Kellner, T Porseryd, I Porsch-Hällström, B Borg, C Roufidou, K H Olsén
Selective Serotonin re-uptake inhibitors (SSRIs) are a class of psychotropic drugs used to treat depression in both adolescents and pregnant or breast-feeding mothers as well as in the general population. Recent research on rodents points to long-lasting behavioural effects of pre- and perinatal exposure to SSRIs which last into adulthood. In fish however, studies on effects of developmental exposure to SSRIs appears to be non-existent. In order to study effects of developmental SSRI exposure in fish, three-spine sticklebacks were exposed to 1...
October 23, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/29055048/adolescent-obesity-and-adult-male-breast-cancer-in-a-cohort-of-1-382-093-men
#15
Lital Keinan-Boker, Hagai Levine, Adi Leiba, Estela Derazne, Jeremy D Kark
Male breast cancer (MBC) accounts for 1% of all breast cancer. Adult obesity and tallness are risk factors for MBC, but the role of adolescent fatness is largely unknown. We aimed to assess the association between body mass index (BMI) in adolescence and the incidence of MBC in a large cohort of 16-19 year-old Israeli males. 1,382,093 Jewish Israeli males aged 16-19 who underwent anthropometric measurements, a General Intelligence Test (GIT) and other examinations during 1967-2011, were followed up to 31.12...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29030158/surgical-treatment-of-adolescent-breast-disorders-institutional-experience-and-national-trends
#16
Brittany L Murphy, Amy Glasgow, Dan S Ubl, Elizabeth B Habermann, Valerie Lemaine
STUDY OBJECTIVE: Adolescent breast disorders are rare and typically benign in nature; however, surgical treatments may require multiple operations. Due to the limited existing data, we sought to evaluate national trends and describe our institutional experience to help guide patient conversations. DESIGN: Retrospective review SETTING: National database and academic institution PARTICIPANTS: Patients ≤20 years old who underwent a breast procedure in the Kids' Inpatient Database (KID) 1/2000-12/2012 and at Mayo Clinic-Rochester 1/2000-7/2016...
October 10, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29028215/spectral-shape-analysis-of-human-torsos-application-to-the-evaluation-of-scoliosis-surgery-outcome
#17
Ola Ahmad, Herve Lombaert, Stefan Parent, Hubert Labelle, Farida Cheriet
OBJECTIVE: This paper aims at evaluating the effect of spinal surgery on the torso shape appearance of adolescent patients. Current methods that assess the surgical outcome on the trunk shape are limited to its global asymmetry or rely on unreliable manual measurements. METHOD: We introduce a novel framework to evaluate pre- to post-operative local asymmetry changes using a spectral representation of the torso shape, more specifically, the Laplacian spectrum (eigenvalues and eigenvectors) of a graph...
October 10, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28992857/anxiety-and-depression-in-cancer-survivors
#18
REVIEW
Jean C Yi, Karen L Syrjala
Most cancer survivors adjust well to life after cancer but some experience persisting negative mood, such as cancer-related fears, posttraumatic stress, anxiety, or depression. Mood fluctuations may not reach criteria for a clinical diagnosis but subclinical symptoms can interfere with quality of life. Women, adolescents, and young adults are particularly at risk for mood disturbances. Behavioral interventions, such as cognitive behavioral therapy and pharmacologic treatments, can effectively treat these distressing emotions...
November 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28987728/environmental-chemicals-and-breast-cancer-an-updated-review-of-epidemiological-literature-informed-by-biological-mechanisms
#19
REVIEW
Kathryn M Rodgers, Julia O Udesky, Ruthann A Rudel, Julia Green Brody
BACKGROUND: Many common environmental chemicals are mammary gland carcinogens in animal studies, activate relevant hormonal pathways, or enhance mammary gland susceptibility to carcinogenesis. Breast cancer's long latency and multifactorial etiology make evaluation of these chemicals in humans challenging. OBJECTIVE: For chemicals previously identified as mammary gland toxicants, we evaluated epidemiologic studies published since our 2007 review. We assessed whether study designs captured relevant exposures and disease features suggested by toxicological and biological evidence of genotoxicity, endocrine disruption, tumor promotion, or disruption of mammary gland development...
October 6, 2017: Environmental Research
https://www.readbyqxmd.com/read/28986442/the-effect-of-reduction-mammaplasty-on-quality-of-life-in-adolescents-with-macromastia
#20
Laura C Nuzzi, Joseph M Firriolo, Carolyn M Pike, Felecia E Cerrato, Michelle L Webb, Heather R Faulkner, Amy D DiVasta, Brian I Labow
OBJECTIVES: To measure changes in health-related quality of life and breast-related symptoms after reduction mammaplasty in adolescents. METHODS: In this longitudinal cohort study, we administered the Short-Form 36v2 (SF-36), Rosenberg Self-Esteem Scale (RSES), Breast-Related Symptoms Questionnaire (BRSQ), and Eating Attitudes Test-26 to 102 adolescents with macromastia and 84 female controls, aged 12 to 21 years. Patients with macromastia completed surveys preoperatively and after reduction mammaplasty at 6 months and 1, 3, and 5 years...
November 2017: Pediatrics
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