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https://www.readbyqxmd.com/read/29029191/evaluating-the-neolithic-expansion-at-both-shores-of-the-mediterranean-sea
#1
João Pimenta, Alexandra M Lopes, David Comas, António Amorim, Miguel Arenas
During the Neolithic, human populations underwent cultural and technological developments that led to an agricultural revolution. Although the population genetics and evolution of European Neolithic populations have been extensively studied, little is known regarding the Neolithic expansion in North Africa with respect to Europe. One could expect that the different environmental and geological conditions at both shores of the Mediterranean Sea could have led to contrasting expansions. In order to test this hypothesis, we compared the Neolithic expansion in Europe and North Africa accounting for possible migration between them through the Strait of Gibraltar...
September 26, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29027349/aerobic-exercise-training-lowers-platelet-reactivity-and-improves-platelet-sensitivity-to-prostacyclin-in-pre-and-postmenopausal-women
#2
M H Lundberg Slingsby, M Nyberg, J Egelund, C M Mandrup, R Frikke-Schmidt, N S Kirkby, Y Hellsten
BACKGROUND: The risk of atherothrombotic events increases after menopause. Regular physical activity has been shown to reduce platelet reactivity in younger women, but it is unknown how regular exercise affects platelet function after menopause. OBJECTIVES: To examine the effects of regular aerobic exercise in late pre- and recent postmenopausal women by testing basal platelet reactivity and platelet sensitivity to prostacyclin and nitric oxide. METHODS: 25 sedentary, but healthy, late premenopausal and 24 matched recently postmenopausal women, mean (95% confidence interval) 49...
October 12, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29026764/a-case-control-study-on-environmental-and-biological-risk-factors-for-renal-calculi-persisting-in-a-coastal-union-territory-india
#3
Prakash Mathiyalagen, Anand Neelakantan, Karthik Balusamy, Kavita Vasudevan, Johnson Cherian, Bhuvaneswary Sunderamurthy
BACKGROUND AND OBJECTIVES: Renal stone disease is a common disorder of the urinary tract and also a significant problem because of incidence, recurrence, and severe consequences. The complex pathogenetic mechanisms of renal stone formation involve both biologic and environmental risk factors. The present study was performed to identify the role of these parameters among renal stone patients and normal individuals from a coastal union territory region in South India. METHODS: The authors conducted a case-control study of renal stone disease among outpatient department patients more than 30 years of age using systematic random sampling procedure with 100 study participants (50 subjects for each group)...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29025901/effects-of-age-and-exercise-training-on-coronary-microvascular-smooth-muscle-phenotype-and-function
#4
Judy M Muller-Delp, Kazuki Hotta, Bei Chen, Bradley Jon Behnke, Joshua J Maraj, Michael D Delp, Tiffani R Lucero, Jeremy A Bramy, David B Alarcon, Hannah E Morgan, Morgan R Cowan, Anthony D Haynes
Coronary microvascular function and blood flow responses during acute exercise are impaired in the aged heart, but can be restored by exercise training. Coronary microvascular resistance is directly dependent on vascular smooth muscle function in coronary resistance arterioles; therefore, we hypothesized that age impairs contractile function and alters the phenotype of vascular smooth muscle in coronary arterioles. We further hypothesized that exercise training restores contractile function and reverses age-induced phenotypic alterations of arteriolar smooth muscle...
October 12, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29025435/withania-somnifera-as-a-potential-candidate-to-ameliorate-high%C3%A2-fat-diet-induced-anxiety-and-neuroinflammation
#5
Taranjeet Kaur, Gurcharan Kaur
BACKGROUND: The epidemic of obesity has reached alarming levels in both developing and developed nations. Excessive calorie intake and sedentary lifestyle due to technological advancements are the main causal factors for overweight and obesity among the human population. Obesity has been associated with a number of co-morbidities such as hypertension, type 2 diabetes mellitus, cardiovascular diseases, and neurodegeneration and dementia. The progression of neurological disorders in obese subjects has been mainly attributed to neuroinflammation...
October 12, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29025130/domain-specific-physical-activity-and-sedentary-behaviour-in-relation-to-colon-and-rectal-cancer-risk-a-systematic-review-and-meta-analysis
#6
Shahid Mahmood, Robert J MacInnis, Dallas R English, Amalia Karahalios, Brigid M Lynch
Background: Physical activity is associated with reduced risk of colorectal cancer, but most epidemiological studies have focused on occupational and recreational physical activity. The evidence for other domains of activity, and for sedentary behaviour, is limited. Methods: Medline, Embase and Web of Science were searched from inception to December 2015 for studies examining domain-specific physical activity or sedentary behaviour and the risk of colon and/or rectal cancer...
August 25, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29025094/the-descriptive-epidemiology-of-the-diurnal-profile-of-bouts-and-breaks-in-sedentary-time-in-older-english-adults
#7
D Yerrakalva, A J Cooper, K Westgate, K T Khaw, N J Wareham, S Brage, S J Griffin, K Wijndaele
Background: High sedentary time is associated with adverse metabolic health outcomes and mortality in older adults. It has been suggested that breaking up sedentary time may be beneficial for metabolic health; however, population prevalence data are lacking on the patterns of sedentary behaviour which would identify opportunities for intervention. Methods: We used data of adults aged ≥ 60 years ( n  = 3705) from the population-based EPIC-Norfolk cohort, to characterize the patterns of total sedentary time, breaks in sedentary time and sedentary bouts across the day and assess their associations with participant characteristics, using multi-level regression...
August 8, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29024599/the-effects-of-combined-probiotic-ingestion-and-circuit-training-on-muscular-strength-and-power-and-cytokine-responses-in-young-males
#8
Nur Syazwani Ibrahim, Ayu Suzailiana Muhamad, Foong Kiew Ooi, Jamaayah Meor-Osman, Chee Keong Chen
To our knowledge, the efficacy of combined probiotic supplementation with circuit training has not been evaluated. Thus, we investigated the effects of probiotic supplementation combined with circuit training on isokinetic muscular strength and power and cytokine responses in young males. Forty-eight healthy sedentary young males were recruited and randomised into four separate groups: sedentary placebo control (C), probiotics (P), circuit training with placebo (CT), and circuit training with probiotics (CTP)...
October 12, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29023580/effects-of-fish-movement-assumptions-on-the-design-of-a-marine-protected-area-to-protect-an-overfished-stock
#9
Jorge Cornejo-Donoso, Baldvin Einarsson, Bjorn Birnir, Steven D Gaines
Marine Protected Areas (MPA) are important management tools shown to protect marine organisms, restore biomass, and increase fisheries yields. While MPAs have been successful in meeting these goals for many relatively sedentary species, highly mobile organisms may get few benefits from this type of spatial protection due to their frequent movement outside the protected area. The use of a large MPA can compensate for extensive movement, but testing this empirically is challenging, as it requires both large areas and sufficient time series to draw conclusions...
2017: PloS One
https://www.readbyqxmd.com/read/29023359/menstrual-disruption-with-exercise-is-not-linked-to-an-energy-availability-threshold
#10
Jay L Lieberman, Mary Jane De Souza, David A Wagstaff, Nancy I Williams
INTRODUCTION: Chronic reductions in energy availability (EA) suppress reproductive function. A particular calculation of EA quantifies the dietary energy remaining after exercise for all physiological functions. Reductions in LH pulse frequency have been demonstrated when EA using this calculation is < 30 kcal/ kg ffm·d. PURPOSE: We determined whether menstrual disturbances (MD) are induced when EA is < 30 kcal/ kg ffm·d. METHODS: Thirty-five sedentary, ovulatory women 18-24 yr (weight= 59...
October 10, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29023342/flexible-work-the-impact-of-a-new-policy-on-employees-sedentary-behaviour-and-physical-activity
#11
Heidi M Olsen, Wendy J Brown, Tracy Kolbe-Alexander, Nicola W Burton
OBJECTIVE: To assess change in physical activity (PA) and sedentary behaviour (SB) in office-based employees following the implementation of a flexible work policy which allowed working at home. METHODS: 24 employees (62% female; 40 ± 10years) completed an online questionnaire four weeks pre- and six weeks post- implementation of the policy. Changes in PA and SB were assessed using Wilcoxon signed-ranks test. RESULTS: There were no changes in PA following the introduction of the flexible work policy (Z = -...
October 11, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29023169/associations-of-physical-activity-and-sedentary-behaviour-with-vision-threatening-diabetic-retinopathy-in-indonesian-population-with-type-2-diabetes-mellitus-jogjakarta-eye-diabetic-study-in-the-community-joged-com
#12
D P Dharmastuti, A N Agni, F Widyaputri, S Pawiroranu, Z M Sofro, F S Wardhana, S Haryanto, T W Widayanti, S Kotha, P Gupta, M B Sasongko
PURPOSE: To investigate the association of physical activity (PA) and sedentary behaviour with diabetic retinopathy (DR) in type 2 diabetes adults. METHODS: A community-based cross-sectional study of adults with type 2 diabetes. DR was assessed from disc- and macula-centred fundus photograph, and categorised into mild, moderate non-proliferative DR (NPDR), and Vision-Threatening DR (VTDR). Worse eye was used to determine the person's DR severity. PA was assessed using WHO Global Physical Activity Questionnaire (GPAQ)...
October 12, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/29022267/cardiac-fibrosis-the-beneficial-effects-of-exercise-in-cardiac-fibrosis
#13
Jan Kyselovič, John J Leddy
Numerous scientific findings have concluded that individuals who are active tend to develop less cardiovascular disease than those who enjoy more sedentary lifestyles. Animal models have further demonstrated that the beneficial effects of training on the heart effects of training are related to the signaling pathways of myocardial hypertrophy and fibrosis. As such, fibroblasts represent a very important population of cells within the myocardium as they play a crucial role in both cardiac development and response to injury...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29021913/exergaming-can-be-an-innovative-way-of-enjoyable-high-intensity-interval-training
#14
Trine Moholdt, Stian Weie, Konstantinos Chorianopoulos, Alf Inge Wang, Kristoffer Hagen
OBJECTIVES: Exergames can replace sedentary time spent on computer gaming with physical activity. Previous research has found exergaming to elicit light-to-moderate exercise intensity. Our primary aim was to examine the exercise intensity of a newly developed biking exergame. METHODS: Eight males (23.9±0.6 years) played the exergame (PLAY) and walked (WALK) on three separate occasions, with the condition counterbalanced and in random sequence within each day. They were asked to PLAY and WALK for a minimum of 15 min and then continue for as long as they wanted...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29021910/the-training-type-influence-on-male-elite-athletes-ventilatory-function
#15
Tijana Durmic, Biljana Lazovic Popovic, Mirjana Zlatkovic Svenda, Marina Djelic, Vladimir Zugic, Tamara Gavrilovic, Zoran Mihailovic, Marija Zdravkovic, Roman Leischik
BACKGROUND/AIM: To assess and compare measured ventilatory volumes (forced expiratory volume in 1 s (FEV1), peak expirium flow (PEF) and maximal voluntary ventilation (MVV)), ventilatory function capacities (forced vital capacity (FVC) and vital capacity (VC)) and FEV1/VC ratio in a sample of power and endurance elite athletes and their age-matched and sex-matched sedentary control group. METHODS: A cross-sectional study was applied on male elite athletes (n=470) who were classified according to the type of the predominantly performed exercise in the following way: group 1: endurance group (EG=270), group 2: power athletes group (SG=200) and group 3: sedentary control group (CG=100)...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29021908/effectiveness-of-a-standardised-exercise-programme-for-recurrent-neck-and-low-back-pain-a-multicentre-randomised-two-arm-parallel-group-trial-across-34-fitness-clubs-in-finland
#16
Jaana H Suni, Marjo Rinne, Kari Tokola, Ari Mänttäri, Tommi Vasankari
BACKGROUND: Neck and low back pain (LBP) are common in office workers. Exercise trials to reduce neck and LBP conducted in sport sector are lacking. We investigated the effectiveness of the standardised Fustra20Neck&Back exercise program for reducing pain and increasing fitness in office workers with recurrent non-specific neck and/or LBP. METHOD: Volunteers were recruited through newspaper and Facebook. The design is a multi-centre randomised, two-arm, parallel group trial across 34 fitness clubs in Finland...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29021899/reliability-of-self-report-measures-of-correlates-of-obesity-related-behaviours-in-hong-kong-adolescents-for-the-ihealt-h-and-ipen-adolescent-studies
#17
Ester Cerin, Cindy H P Sit, Anthony Barnett, Wendy Y J Huang, Gemma Y Gao, Stephen H S Wong, James F Sallis
BACKGROUND: This study examined the reliability of measures of correlates of dietary behaviours (DBs), physical activity (PA) and sedentary behaviour (SB) for Hong Kong adolescents. METHOD: Individual, social and environmental correlates of obesity-related behaviours were assessed twice, 15-27 days apart (average 20 days), via self-administered questionnaires. These questionnaire included measures of decisional balance, self-efficacy, enjoyment and social support related to intake of fruits, vegetables, high-fat foods and sugar-sweetened beverages, PA behaviour and SB...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29020958/does-replacing-sedentary-behaviour-with-light-or-moderate-to-vigorous-physical-activity-modulate-inflammatory-status-in-adults
#18
Catherine M Phillips, Christina B Dillon, Ivan J Perry
BACKGROUND: Sedentary behaviour, obesity and insulin resistance are associated with pro-inflammatory status. Limited data on whether physical activity modulates inflammatory status and counteracts obesity and insulin resistance associated low-grade inflammation exist. Our objective was to investigate associations between objectively measured physical activity and inflammatory status, and specifically whether substituting daily sedentary behaviour with light activity or moderate to vigorous physical activity (MVPA), is associated with beneficial alterations to the inflammatory profile among middle-aged adults and those at increased cardiometabolic risk (obese and insulin resistant subjects)...
October 11, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29019419/prenatal-exposure-to-endocrine-disruptors-and-reprogramming-of-adipogenesis-an-early-life-risk-factor-for-childhood-obesity
#19
Ayman El-Sayed Shafei, Enas Samir Nabih, Kirolos Atalla Shehata, Emad Sherif Mohamed Abd Elfatah, Abou Bakr Ahmed Sanad, Mohamed Yehia Marey, Abd Alla Mohamed Ahmed Hammouda, Mounir Mostafa Moussa Mohammed, Randa Mostafa, Mahmoud A Ali
Obesity is a global health problem. It is characterized by excess adipose tissue that results from either increase in the number of adipocytes or increase in adipocytes size. Adipocyte differentiation is a highly regulated process that involves the activation of several transcription factors culminating in the removal of adipocytes from the cell cycle and induction of highly specific proteins. Several other factors, including hormones, genes, and epigenetics, are among the most important triggers of the differentiation process...
October 11, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29019279/leucine-and-resistance-training-improve-hyperglycemia-white-adipose-tissue-loss-and-inflammatory-parameters-in-an-experimental-model-of-type-1-diabetes
#20
Henrique Quintas Teixeira Ribeiro, Audrey Yule Coqueiro, Vanessa Batista de Sousa Lima, Carlos Eduardo Carvalho Martins, Julio Tirapegui
BACKGROUND: Loss of white adipose tissue (WAT), associated with type 1 diabetes (DM1), contributes to increased chronic systemic inflammation. AIM: The aim of this study was to investigate the effects of leucine supplementation and resistance training (RT) in attenuating WAT loss and improving inflammatory parameters and glucose metabolism in DM1 rats. METHODS: Thirty-two male Wistar rats were distributed into four groups: DA (sedentary and supplemented with non-essential amino acids (NEAA)), DL (sedentary and supplemented with leucine), DTA (submitted to RT and supplemented with NEAA) and DTL (submitted to RT and supplemented with leucine)...
January 1, 2017: Nutrition and Health
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