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https://www.readbyqxmd.com/read/28646578/the-impact-of-a-novel-transendometrial-approach-for-caesarean-myomectomy-on-obstetric-outcomes-of-subsequent-pregnancy-a-longitudinal-panel-study
#1
S Y Huang, S W Shaw, S Y Su, W F Li, H H Peng, P J Cheng
OBJECTIVE: To evaluate the obstetric and surgical outcomes of a novel transendometrial approach for myomectomy during caesarean section in subsequent pregnancies. DESIGN: Longitudinal panel study. SETTING: Chang Gung Memorial Hospital, Taiwan, with approximately 5000 births per annum. POPULATION: Pregnant women complicated with uterine myoma. METHOD: Sixty-three pregnant women who received transendometrial myomectomy during the first caesarean delivery reported a subsequent live pregnancy and planned an elective repeat caesarean delivery...
June 24, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28643658/quality-assessment-of-pelvic-ultrasound-for-uterine-myoma-according-to-the-cngof-guidelines
#2
D Perrot, H Fernandez, J M Levaillant, P Capmas
INTRODUCTION: French guidelines regarding the minimum criteria for gynaecological ultrasound were given in a recent report in 2016, by the French National College of Obstetricians and Gynaecologists (CNGOF). An accurate report is essential for the optimal care of women, especially those presenting myomas. The goal of this study was to evaluate the quality of gynaecological ultrasound reports for women with type 0 to 2 uterine myomas, referring to the items contained in the French guidelines...
April 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28631712/-the-molecular-mechanisms-and-morphological-manifestations-of-leiomyoma-reduction-induced-by-selective-progesterone-receptor-modulators
#3
T A Demura, Z V Revazova, E A Kogan, L V Adamyan
AIM: to investigate the molecular mechanisms and morphological substrate of reduced uterine leiomyoma in patients receiving the selective progesterone receptor modulator (SPRM) ulipristal acetate for 3 months, by estimating the immunohistochemical expression of the markers steroid receptor coactivator 1 (SRC-1), nuclear receptor corepressor 1 (NCoR-1), ER, PgR, Ki-67, p16, TGF-β, and VEGF in tumor tissue. SUBJECTS AND METHODS: The investigation enrolled 75 women with uterine leiomyoma, menorrhagias, and anemia...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28609115/molecular-targets-of-dietary-phytochemicals-for-possible-prevention-and-therapy-of-uterine-fibroids-focus-on-fibrosis
#4
Md Soriful Islam, Most Mauluda Akhtar, James H Segars, Mario Castellucci, Pasquapina Ciarmela
Uterine fibroids (myomas or leiomyomas) are common benign tumors of reproductive aged women. Fibroids are clinically apparent in 20-50% of women, and cause abnormal uterine bleeding, abdominal pain and discomfort, pregnancy complications and infertility. Unfortunately, limited numbers of medical treatment are available but no effective preventive strategies exist. Moreover, the benefits of medical treatments are tempered by lack of efficacy or serious adverse side effects. Fibrosis has recently been recognized as a key pathological event in leiomyoma development and growth...
November 22, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28599883/uterine-sparing-laparoscopic-resection-of-accessory-cavitated-uterine-masses
#5
Ann Peters, Noah B Rindos, Richard S Guido, Nicole M Donnellan
To demonstrate surgical techniques utilized during uterine-sparing laparoscopic resections of accessory cavitated uterine masses (ACUM) BACKGROUND: ACUM represent a rare uterine entity observed in premenopausal women suffering from dysmenorrhea and recurrent pelvic pain. The diagnosis is made when an isolated extra-cavitated uterine mass is resected from an otherwise normal appearing uterus with unremarkable endometrial lumen and adnexal structures. Pathologic confirmation requires an accessory cavity lined with endometrial epithelium (and corresponding glands and stroma) filled with chocolate-brown fluid...
June 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28597115/psychiatric-outcomes-after-hysterectomy-in-women-with-uterine-myoma-a-population-based-retrospective-cohort-study
#6
Hyo Jung Lee, Seung Ju Kim, Eun-Cheol Park
Controversy regarding psychological or psychiatric outcomes following hysterectomy still exists. The purpose of this study was to investigate the risk of postoperative psychiatric disorders in women with hysterectomy compared to that in women with uterus-conserving surgery for myomas by using population-based data from South Korea. This study was designed as a retrospective cohort study. We analyzed the National Health Insurance Service National Sample Cohort data including all administrative medical claims from 2002 to 2013...
June 9, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28588782/rapidly-progressing-large-cell-neuroendocrine-carcinoma-arising-from-the-uterine-corpus-a-case-report-and-review-of-the-literature
#7
Aya Kobayashi, Tamaki Yahata, Sakiko Nanjo, Mika Mizoguchi, Madoka Yamamoto, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Kazuhiko Ino
Large-cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine tumor. LCNECs arising from the genital organs are highly malignant and rare, with <20 cases of LCNEC developing from the uterine endometrium reported to date. We herein present the case of a patient with LCNEC of the endometrium. The patient was a 52-year-old woman, who exhibited lower abdominal pain and rapid uterine enlargement during outpatient treatment for uterine myoma. The endometrial biopsy suggested a diagnosis of poorly differentiated carcinoma or carcinosarcoma...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28586129/psychometric-validation-of-the-chinese-version-of-the-illness-perception-questionnaire-revised-for-women-with-stress-urinary-incontinence
#8
Yijun Fan, Zhaohui Huang, Dazhao Zhang, Jun Chang, Yun Jia, Shuihong He, Bing Wei
AIM: The aim of this study was to examine the reliability and validity of the Illness Perception Questionnaire-Revised (IPQ-R) in patients with stress urinary incontinence (SUI). METHODS: A total of 256 patients with SUI and 76 patients with myoma of the uterus were recruited to complete the Chinese IPQ-R. For the reliability, the key tests included Cronbach's α coefficient and intraclass correlation coefficients. For the validity, the key tests included factor analysis, Spearman's correlation coefficient, and the Student's t-test...
June 6, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28585458/safety-of-cesarean-myomectomy-in-women-with-single-anterior-wall-and-lower-uterine-segment-myomas
#9
Radmila Sparić, Antonio Malvasi, Saša Kadija, Aleksandar Stefanović, Svetlana Spremović Radjenović, Jela Popović, Aleksandra Pavić, Andrea Tinelli
OBJECTIVE: Cesarean myomectomy (CM) is a safe procedure in selected cases. Nevertheless, literature lacks clear guidelines on patient selection. We aimed to evaluate CM safety in patients with single anterior wall and lower uterine segment (LUS) myomas. METHODS: The authors selected pregnants at term, scheduled for CSs, with single anterior wall or LUS myomas. All their clinical, demographic, obstetric, and surgical parameters were recorded. RESULTS: Thirty-six women had a CM (study group), and 17 had a CS without myoma removal (control group)...
June 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28547742/increased-annexin-a2-and-decreased-%C3%AE-catenin-in-adenomyosis-contribute-to-adenomyosis-associated-dysmenorrhea
#10
Li Xue Liu, Yin Ga Wu, Jian Zheng
OBJECTIVE: To investigate the expression of annexin A2 (ANXA2) and β-catenin in eutopic and ectopic endometrium, and their relationships with adenomyosis-associated dysmenorrhea. METHODS: From December 2013 to June 2014, ectopic endometrium (n=30) and eutopic endometrium (n=30) of adenomyosis were collected as experimental group, and endometrium (n=30) of uterine myoma as control group from the department of gynecology and obstetrics, the affiliated hospital of Inner Mongolia medical university...
May 26, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28530622/-laparoscopic-uretero-ureterostomy-for-iatrogenic-lesions-of-the-distal-ur%C3%A3-ter
#11
Álvaro Juárez Soto, Rubén Campanario Pérez, Rocío Sáiz Marenco, Javier Amores Bermúdez, Manuel Soto Delgado, Jose Miguel Arroyo Maestre, Margarita De Paz Suárez
The most frequent ureteral lesions are iatrogenic, mainly due to gynecologic and urologic procedures. The resolution and repair of these lesions, when they require surgery, is often the performance of ureteroneocystostomy. We describe the technique for the repair of distal ureter lesions that preserves both anatomy and function of the urinary tract (1). The operation consists in dissection and extraction of the distal ureteral stump from its intramural tract to get at least 1 cm of free ureter, percutaneous insertion of a ureteral stent, checking the absence of tension between proximal ureter and distal dissected stump, end to end anastomosis and reinsertion of the distal ureter in the previously dissected bladder muscle layer...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28526008/cleavage-of-the-urokinase-receptor-upar-on-oral-cancer-cells-regulation-by-transforming-growth-factor-%C3%AE-1-tgf-%C3%AE-1-and-potential-effects-on-migration-and-invasion
#12
Synnove Norvoll Magnussen, Elin Hadler-Olsen, Daniela Elena Costea, Eli Berg, Cristiane Cavalcanti Jacobsen, Bente Mortensen, Tuula Salo, Inigo Martinez-Zubiaurre, Jan-Olof Winberg, Lars Uhlin-Hansen, Gunbjorg Svineng
BACKGROUND: Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously observed elevated expression of uPAR at the tumour-stroma interface in a mouse model for OSCC, which was associated with increased proteolytic activity. The tumour microenvironment regulated uPAR expression, as well as its glycosylation and cleavage. Both full-length- and cleaved uPAR (uPAR (II-III)) are involved in highly regulated processes such as cell signalling, proliferation, migration, stem cell mobilization and invasion...
May 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28523198/uterine-fibroid-torsion-during-pregnancy-a-case-of-laparotomic-myomectomy-at-18-weeks-gestation-with-systematic-review-of-the-literature
#13
Annachiara Basso, Mariana Rita Catalano, Giuseppe Loverro, Serena Nocera, Edoardo Di Naro, Matteo Loverro, Mariateresa Natrella, Salvatore Andrea Mastrolia
Uterine myomas are the most common benign growths affecting female reproductive system, occurring in 20-40% of women, whereas the incidence rate in pregnancy is estimated from 0.1 to 3.9%. The lower incidence in pregnancy is due to the association with infertility and low pregnancy rates and implantation rates after in vitro fertilization treatment. Uterine myomas, usually, are asymptomatic during pregnancy. However, occasionally, pedunculated fibroids torsion or other superimposed complications may cause acute abdominal pain...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28515917/total-laparoscopic-hysterectomy-for-large-uterine-cervical-myoma
#14
Kentaro Nakayama, Mayu Tsukao, Masako Ishikawa, Tomoka Ishibashi, Kohei Nakamura, Kaori Sanuki, Hitomi Yamashita, Ruriko Ono, Toshiko Minamoto, Satoru Kyo
Ureterolysis is a surgical method with a high level of difficulty, which may be necessary when performing total laparoscopic hysterectomy (TLH) for large cervical myoma, despite the benign nature of this tumor. The aim of the present study was to introduce techniques that are commonly applied in malignant tumor surgery in order to safely perform TLH for large cervical myoma. Between 2014 and 2016, TLH was performed at the Shimane University Hospital (Izumo, Japan) in 153 patients with benign tumors, including 25 cases with a large uterus (uterine weight ≥500 g)...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28507642/diagnostic-imaging-of-pregnant-women-the-role-of-magnetic-resonance-imaging
#15
Monika Bekiesińska-Figatowska, Anna Romaniuk-Doroszewska, Sylwia Szkudlińska-Pawlak, Agnieszka Duczkowska, Jarosław Mądzik, Martyna Szopa-Krupińska, Tomasz M Maciejewski
BACKGROUND: Presentation of magnetic resonance imaging (MRI) findings in pregnant women in the Department of Diagnostic Imaging, Institute of Mother and Child, Warsaw, Poland. MATERIAL/METHODS: Forty-three symptomatic pregnant women underwent MRI between 9 and 33 weeks of gestation (mean of 23 weeks). Moreover, we included 2 pregnant women who underwent fetal MRI and had incidental abnormalities. RESULTS: In 9 cases, we excluded the suspected brain abnormalities...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28503470/falsely-elevated-postvoid-residual-urine-volume-in-uterine-myoma
#16
Tae Hee Kim, Hyo Sang Kim, Jung Wook Park, Oh Kyung Lim, Ki Deok Park, Ju Kang Lee
Precise measurement of postvoid residual (PVR) urine volume is a key factor in assessing patients with voiding dysfunction, including those with lower urinary tract problems. The safe and noninvasive ultrasound bladder scan is the preferred mode to measure PVR volume. However, this procedure has a false-positive rate up to 9%, in the presence of ovarian cysts, renal cysts, ascites, or uterine myoma with cystic degeneration. Until now, cystic lesions are known to cause false positivity in ultrasound bladder scanner...
April 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28498262/sarcoma-risk-in-uterine-surgery-in-a-tertiary-university-hospital-in-germany
#17
Sudip Kundu, Manuel Zachen, Hermann Hertel, Peter Hillemanns, Philipp Soergel
OBJECTIVES: There is a risk to incidentally spread uterine malignancies, especially sarcoma, if tissue is morcellated during hysterectomy or myoma enucleation. In the last years, a worldwide discussion has been started about this problem. However, the risk seems to be very small in recent studies. This study aims at further investigating the risk of disseminating uterine malignancy during uterine surgery in a tertiary university hospital in Germany. METHODS: In a retrospective setting, all cases of uterine myometrial surgery (hysterectomies and myomectomies) in our clinic during a period of 10 years were identified using clinical databases...
June 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28487176/feasibility-of-reduced-port-robotic-surgery-for-myomectomy-with-the-da-vinci-%C3%A2-surgical-system
#18
Jeong Jin Kim, Chahien Choi, Su Hyun Nam, Woo Young Kim
STUDY OBJECTIVE: To present our initial experience with reduced port robotic surgery (RPRS) for myomectomy using Octo-Port. DESIGN: Prospective and noncomparative study. (Canadian Task Force classification II-3). SETTING: University hospital. PATIENTS: Nineteen consecutive patients with symptomatic uterine fibroids desiring conservative minimally invasive robotic surgery from October 2015 to December 2016 INTERVENTIONS: An 8...
May 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28486366/changes-in-myomectomy-practice-after-the-u-s-food-and-drug-administration-safety-communication-on-power-morcellation
#19
Natalie C Stentz, Laura G Cooney, Mary Sammel, Divya K Shah
OBJECTIVE: To examine the association between the 2014 U.S. Food and Drug Administration (FDA) safety communication on power morcellation and surgical approach and morbidity after myomectomy. METHODS: In this retrospective cohort study, data were abstracted from the American College of Surgeons National Surgical Quality Improvement Program database on 3,160 myomectomies between April 2012 and December 2013 (pre-FDA) and 4,378 between April 2014 and December 2015 (post-FDA)...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28481790/a-novel-diagnostic-strategy-using-16%C3%AE-18f-fluoro-17-%C3%AE-estradiol-18f-fes-pet-mri-to-achieve-complete-resection-of-intravenous-leiomyomatosis-in-reproductive-age-women
#20
Yoko Chino, Hideaki Tsuyoshi, Tetsuya Tsujikawa, Hidehiko Okazawa, Yoshio Yoshida
Intravenous leiomyomatosis is a life-threatening leiomyoma that grows into the extrauterine venous system. A high recurrence rate has been reported in reproductive-age women who undergo only tumor excision to preserve fertility. Precise diagnosis of tumor extension is essential to achieve complete resection. A 24-year-old woman presented with hypermenorrhea. Contrast-enhanced MRI showed an intramural myoma with worm-like extension into the right parametrium. F-FES PET/MRI accurately depicted the extension with strong FES activity into the right uterine vein, whereas F-FDG PET/MRI excluded the possibility of malignancy...
July 2017: Clinical Nuclear Medicine
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