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Spatial epidemiology

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https://www.readbyqxmd.com/read/27916702/chronic-kidney-disease-accelerates-cognitive-impairment-in-a-mouse-model-of-alzheimer-s-disease-through-angiotensin-ii
#1
Takashi Nakagawa, Yu Hasegawa, Ken Uekawa, Shokei Kim-Mitsuyama
Epidemiological studies suggest that chronic kidney disease (CKD) is a significant risk factor in the development of cognitive decline. However, the exact role of CKD in cognitive impairment or dementia is unclear. This work was performed to examine the potential impact of CKD on cognitive impairment in Alzheimer's disease (AD), focusing on angiotensin II. (1) CKD was induced in 5XFAD mice, an AD model mouse, and wild-type mice by feeding adenine-containing diet and the effect on cognitive function was compared between both strains...
December 1, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27916311/land-use-regression-modeling-of-ultrafine-particles-ozone-nitrogen-oxides-and-markers-of-particulate-matter-pollution-in-augsburg-germany
#2
Kathrin Wolf, Josef Cyrys, Tatiana Harciníková, Jianwei Gu, Thomas Kusch, Regina Hampel, Alexandra Schneider, Annette Peters
Important health relevance has been suggested for ultrafine particles (UFP) and ozone, but studies on long-term effects are scarce, mainly due to the lack of appropriate spatial exposure models. We designed a measurement campaign to develop land use regression (LUR) models to predict the spatial variability focusing on particle number concentration (PNC) as indicator for UFP, ozone and several other air pollutants in the Augsburg region, Southern Germany. Three bi-weekly measurements of PNC, ozone, particulate matter (PM10, PM2...
December 1, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27915227/prenatal-and-postnatal-polybrominated-diphenyl-ether-exposure-and-visual-spatial-abilities-in-children
#3
Ann M Vuong, Joseph M Braun, Kimberly Yolton, Changchun Xie, Glenys M Webster, Andreas Sjödin, Kim N Dietrich, Bruce P Lanphear, Aimin Chen
Polybrominated diphenyl ethers (PBDEs) are associated with impaired visual spatial abilities in toxicological studies, but no epidemiologic study has investigated PBDEs and visual spatial abilities in children. The Health Outcomes and Measures of the Environment Study, a prospective birth cohort (2003-2006, Cincinnati, OH), was used to examine prenatal and childhood PBDEs and visual spatial abilities in 199 children. PBDEs were measured at 16±3 weeks gestation and at 1, 2, 3, 5, and 8 years using gas chromatography/isotope dilution high-resolution mass spectrometry...
December 1, 2016: Environmental Research
https://www.readbyqxmd.com/read/27913438/quantifying-the-dynamics-of-field-cancerization-in-tobacco-related-head-and-neck-cancer-a-multiscale-modeling-approach
#4
Marc D Ryser, Walter T Lee, Neal E Ready, Kevin Z Leder, Jasmine Foo
High rates of local recurrence in tobacco-related head and neck squamous cell carcinoma (HNSCC) are commonly attributed to unresected fields of precancerous tissue. Because they are not easily detectable at the time of surgery without additional biopsies, there is a need for noninvasive methods to predict the extent and dynamics of these fields. Here, we developed a spatial stochastic model of tobacco-related HNSCC at the tissue level and calibrated the model using a Bayesian framework and population-level incidence data from the Surveillance, Epidemiology, and End Results (SEER) registry...
October 20, 2016: Cancer Research
https://www.readbyqxmd.com/read/27912766/non-random-distribution-of-child-undernutrition-in-ethiopia-spatial-analysis-from-the-2011-ethiopia-demographic-and-health-survey
#5
Zewdie Aderaw Alemu, Ahmed Ali Ahmed, Alemayehu Worku Yalew, Belay Simanie Birhanu
BACKGROUND: Child undernutrition showed geographical inequalities due to variations in contextual determinants from area to area which indicates that location is an important factor in child undernutrition. However, there are limited studies on spatial epidemiology of child undernutrition in Ethiopia. This study was aimed to identify the SaTScan spatial clusters of child undernutrition in Ethiopia. METHODS: Nutritional indices of children (0-59 months) with Global Positioning System (GPS) location data were accessed from the 2011 Ethiopia Demographic and Health Survey (EDHS) after getting permission from the MEASURES Demographic and Health Survey (DHS) Program...
December 3, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27905962/identifying-potential-differences-in-cause-of-death-coding-practices-across-russian-regions
#6
Inna Danilova, Vladimir M Shkolnikov, Dmitri A Jdanov, France Meslé, Jacques Vallin
BACKGROUND: Reliable and comparable data on causes of death are crucial for public health analysis, but the usefulness of these data can be markedly diminished when the approach to coding is not standardized across territories and/or over time. Because the Russian system of producing information on causes of death is highly decentralized, there may be discrepancies in the coding practices employed across the country. In this study, we evaluate the uniformity of cause-of-death coding practices across Russian regions using an indirect method...
March 22, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27903308/joint-spatial-time-series-epidemiological-analysis-of-malaria-and-cutaneous-leishmaniasis-infection
#7
O A Adegboye, M Al-Saghir, D H Y Leung
Malaria and leishmaniasis are among the two most important health problems of many developing countries especially in the Middle East and North Africa. It is common for vector-borne infectious diseases to have similar hotspots which may be attributed to the overlapping ecological distribution of the vector. Hotspot analyses were conducted to simultaneously detect the location of local hotspots and test their statistical significance. Spatial scan statistics were used to detect and test hotspots of malaria and cutaneous leishmaniasis (CL) in Afghanistan in 2009...
December 1, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27903065/predominance-and-geo-mapping-of-avian-influenza-h5n1-in-poultry-sectors-in-egypt
#8
Abdelsatar Arafa, Ihab El-Masry, Shereen Khoulosy, Mohammed K Hassan, Moussa Soliman, Olubunmi G Fasanmi, Folorunso O Fasina, Gwenaelle Dauphin, Juan Lubroth, Yilma M Jobre
Highly pathogenic avian influenza (HPAI) virus of the H5N1 subtype has been enzootic in the Egyptian poultry with significant human infections since 2008. This work evaluates the epidemiological and virological information from February 2006 to May 2015 in spatial and temporal terms. Only data with confirmed HPAI H5N1 sub-type were collected, and matched with the epidemiological data from various spatially and temporally-dispersed surveillances implemented between 2006 and 2015. Spatio-temporal analysis was conducted on a total of 3338 confirmed H5N1 HPAI poultry disease outbreaks and outputs described based on transmission patterns, poultry species, production types affected, trade, geographic and temporal distributions in Egypt...
November 28, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27903058/space-time-epidemiology-and-effect-of-meteorological-parameters-on-influenza-like-illness-in-phitsanulok-a-northern-province-in-thailand
#9
Prakash Madhav Nimbalkar, Nitin Kumar Tripathi
Influenza-like illness (ILI) is an acute respiratory disease that remains a public health concern for its ability to circulate globally affecting any age group and gender causing serious illness with mortality risk. Comprehensive assessment of the spatio-temporal dynamics of ILI is a prerequisite for effective risk assessment and application of control measures. Though meteorological parameters, such as rainfall, average relative humidity and temperature, influence ILI and represent crucial information for control of this disease, the relation between the disease and these variables is not clearly understood in tropical climates...
November 21, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27903050/random-forest-variable-selection-in-spatial-malaria-transmission-modelling-in-mpumalanga-province-south-africa
#10
Thandi Kapwata, Michael T Gebreslasie
Malaria is an environmentally driven disease. In order to quantify the spatial variability of malaria transmission, it is imperative to understand the interactions between environmental variables and malaria epidemiology at a micro-geographic level using a novel statistical approach. The random forest (RF) statistical learning method, a relatively new variable-importance ranking method, measures the variable importance of potentially influential parameters through the percent increase of the mean squared error...
November 16, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27902960/optimising-measurement-of-health-related-characteristics-of-the-built-environment-comparing-data-collected-by-foot-based-street-audits-virtual-street-audits-and-routine-secondary-data-sources
#11
Triantafyllos Pliakas, Sophie Hawkesworth, Richard J Silverwood, Kiran Nanchahal, Chris Grundy, Ben Armstrong, Juan Pablo Casas, Richard W Morris, Paul Wilkinson, Karen Lock
The role of the neighbourhood environment in influencing health behaviours continues to be an important topic in public health research and policy. Foot-based street audits, virtual street audits and secondary data sources are widespread data collection methods used to objectively measure the built environment in environment-health association studies. We compared these three methods using data collected in a nationally representative epidemiological study in 17 British towns to inform future development of research tools...
November 27, 2016: Health & Place
https://www.readbyqxmd.com/read/27891781/geographic-distribution-of-live-births-with-tetralogy-of-fallot-in-north-carolina-2003-to-2012
#12
Jennifer S Nelson, Rebecca C Stebbins, Paula D Strassle, Robert E Meyer
BACKGROUND: Geographic variation in congenital heart disease is not well-described. This study uses geographic information systems (GIS) to describe the spatial epidemiology of tetralogy of Fallot (TOF), in North Carolina (NC) and to compare travel time for cases to congenital heart centers in NC. METHODS: Using the NC Birth Defects Monitoring Program database, live births with TOF born between 2003 and 2012 were identified. Birth certificates provided demographic variables...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27889213/spatiotemporal-estimation-of-air-temperature-patterns-at-the-street-level-using-high-resolution-satellite-imagery
#13
Ran Pelta, Alexandra A Chudnovsky
Although meteorological monitoring stations provide accurate measurements of Air Temperature (AT), their spatial coverage within a given region is limited and thus is often insufficient for exposure and epidemiological studies. In many applications, satellite imagery measures energy flux, which is spatially continuous, and calculates Brightness Temperature (BT) that used as an input parameter. Although both quantities (AT-BT) are physically related, the correlation between them is not straightforward, and varies daily due to parameters such as meteorological conditions, surface moisture, land use, satellite-surface geometry and others...
November 23, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27887696/reprint-of-neurocysticercosis-related-mortality-in-brazil-2000-2011-epidemiology-of-a-neglected-neurologic-cause-of-death
#14
Francisco Rogerlândio Martins-Melo, Alberto Novaes Ramos, Marta Guimarães Cavalcanti, Carlos Henrique Alencar, Jorg Heukelbach
Neurocysticercosis (NCC) is an important cause of severe neurological disease mainly in low- and middle-income countries, but data on NCC mortality from endemic areas are scarce. Here we analysed the epidemiological patterns of NCC-related mortality in Brazil. We included all deaths recorded in Brazil between 2000 and 2011, in which NCC was mentioned on death certificates, either as underlying or as associated cause of death. NCC was identified in 1829/12,491,280 deaths (0.015%), 1130 (61.8%) as underlying cause, and 699 (38...
November 22, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27884187/a-simulation-study-to-quantify-the-impacts-of-exposure-measurement-error-on-air-pollution-health-risk-estimates-in-copollutant-time-series-models
#15
Kathie L Dionisio, Howard H Chang, Lisa K Baxter
BACKGROUND: Exposure measurement error in copollutant epidemiologic models has the potential to introduce bias in relative risk (RR) estimates. A simulation study was conducted using empirical data to quantify the impact of correlated measurement errors in time-series analyses of air pollution and health. METHODS: ZIP-code level estimates of exposure for six pollutants (CO, NOx, EC, PM2.5, SO4, O3) from 1999 to 2002 in the Atlanta metropolitan area were used to calculate spatial, population (i...
November 25, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27884172/spatial-distribution-and-trypanosome-infection-of-tsetse-flies-in-the-sleeping-sickness-focus-of-zimbabwe-in-hurungwe-district
#16
William Shereni, Neil E Anderson, Learnmore Nyakupinda, Giuliano Cecchi
BACKGROUND: In Zimbabwe, cases of human African trypanosomiasis (HAT) are caused by the unicellular protozoan Trypanosoma brucei, sub-species T. b. rhodesiense. They are reported from the tsetse-infested area in the northern part of the country, broadly corresponding to the valley of the Zambezi River. Tsetse-transmitted trypanosomes, in particular T. congolense and T. vivax, also cause morbidity and mortality in livestock, thus generating poverty and food insecurity. Two species of tsetse fly, Glossina morsistans morsitans and G...
November 25, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27883281/severe-mortality-impact-of-the-1957-influenza-pandemic-in-chile
#17
Gerardo Chowell, Lone Simonsen, Rodrigo Fuentes, Jose Flores, Mark A Miller, Cécile Viboud
INTRODUCTION: Epidemiological studies of the 1957 influenza pandemic are scarce, particularly from lower income settings. METHODS: We analyzed the spatial-temporal mortality patterns of the 1957 influenza pandemic in Chile including detailed age-specific mortality data from a large city and investigated risk factors for severe mortality impact across regions. RESULTS: Chile exhibited two waves of excess mortality in winter 1957 and 1959 with a cumulative excess mortality rate of 12 per 10,000, and a ~10-fold mortality difference across provinces...
November 24, 2016: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/27881169/spatiotemporal-exposure-modeling-of-ambient-erythemal-ultraviolet-radiation
#18
Trang VoPham, Jaime E Hart, Kimberly A Bertrand, Zhibin Sun, Rulla M Tamimi, Francine Laden
BACKGROUND: Ultraviolet B (UV-B) radiation plays a multifaceted role in human health, inducing DNA damage and representing the primary source of vitamin D for most humans; however, current U.S. UV exposure models are limited in spatial, temporal, and/or spectral resolution. Area-to-point (ATP) residual kriging is a geostatistical method that can be used to create a spatiotemporal exposure model by downscaling from an area- to point-level spatial resolution using fine-scale ancillary data...
November 24, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27878104/geographic-integration-of-hepatitis-c-virus-a-global-threat
#19
Mohamed A Daw, Abdallah A El-Bouzedi, Mohamed O Ahmed, Aghnyia A Dau, Mohamed M Agnan, Aisha M Drah
AIM: To assess hepatitis C virus (HCV) geographic integration, evaluate the spatial and temporal evolution of HCV worldwide and propose how to diminish its burden. METHODS: A literature search of published articles was performed using PubMed, MEDLINE and other related databases up to December 2015. A critical data assessment and analysis regarding the epidemiological integration of HCV was carried out using the meta-analysis method. RESULTS: The data indicated that HCV has been integrated immensely over time and through various geographical regions worldwide...
November 12, 2016: World Journal of Virology
https://www.readbyqxmd.com/read/27869653/semiparametric-multinomial-ordinal-model-to-analyze-spatial-patterns-of-child-birth-weight-in-nigeria
#20
Rasheed A Adeyemi, Temesgen Zewotir, Shaun Ramroop
Background: Birth weight is an important health parameter for obstetricians and gynaecologists. It is a good health indicator of a child-bearing mother and a strong predictor of infant morbidity and mortality. Methods: This paper utilizes data on 28,647 children born between 2003-2008 obtained from the 2008 Nigeria Demographic and Health Survey (NDHS). For a simple epidemiological convenience, the occurrence of a newborn weight can intuitively be considered to be categorical in nature and the thresholds can be put on a continuous scale...
November 17, 2016: International Journal of Environmental Research and Public Health
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