P Asensi Cantó, J Sanz Caballer, C Sopeña Pell-Ilderton, J Solís Ruiz, P Lloret Madrid, M Montaner Villalba, A Facal Malvar, P Chorão, M Guerreiro, A Balaguer Roselló, J Montoro Gómez, M Santiago Balsera, P Solves Alcaína, M A Sanz Alonso, J De la Rubia Comos, I Gómez-Seguí
INTRODUCTION: Extracorporeal photopheresis (ECP) has shown efficacy in graft-versus-host disease (GVHD). We aim to summarize eight years of real-world experience with off-line ECP in our institution, in order to validate this treatment schedule and analyze predictive factors. MATERIALS AND METHODS: All consecutive adult patients with steroid-dependent or steroidrefractory GVHD receiving off-line ECP were included in this single center, retrospective study. ECP was performed with Spectra Optia®, processing one total blood volume, with a frequency of twice a week for acute GVHD and once a week for chronic GVHD, and tapered individually according to clinical response...
September 11, 2023: Transplantation and cellular therapy