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https://www.readbyqxmd.com/read/27803490/impact-of-homocysteine-level-on-long-term-cardiovascular-outcomes-in-patients-after-coronary-artery-stenting
#1
Jih-Kai Yeh, Chun-Chi Chen, Ming-Jer Hsieh, Ming-Lung Tsai, Chia-Hung Yang, Dong-Yi Chen, Shang-Hung Chang, Chao-Yung Wang, Cheng-Hung Lee, I-Chang Hsieh
AIM: The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. The objective of this study was to investigate whether elevated HCY level at admission predict long-term outcomes in patients after percutaneous coronary interventions (PCI) with coronary artery stenting. METHODS: From the institutional registry of Cardiovascular Atherosclerosis and Percutaneous TrAnsluminal INterventions (CAPTAIN), we enrolled a total of 1,307 patients with documented CAD undergone PCI with bare metal stents from July 2003 to December 2014...
November 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27782041/neonicotinoid-insecticides-alter-the-gene-expression-profile-of-neuron-enriched-cultures-from-neonatal-rat-cerebellum
#2
Junko Kimura-Kuroda, Yasumasa Nishito, Hiroko Yanagisawa, Yoichiro Kuroda, Yukari Komuta, Hitoshi Kawano, Masaharu Hayashi
Neonicotinoids are considered safe because of their low affinities to mammalian nicotinic acetylcholine receptors (nAChRs) relative to insect nAChRs. However, because of importance of nAChRs in mammalian brain development, there remains a need to establish the safety of chronic neonicotinoid exposures with regards to children's health. Here we examined the effects of longterm (14 days) and low dose (1 μM) exposure of neuron-enriched cultures from neonatal rat cerebellum to nicotine and two neonicotinoids: acetamiprid and imidacloprid...
October 4, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27704472/-revival-after-ebola-multidisciplinary-assessment-at-1-year-prospect-and-follow-up-study-of-surviving-patients-from-ebola-in-guinea-postebogui-cohort
#3
P Msellati, A Touré, M S Sow, K Cécé, B Taverne, A Desclaux, M Barry, J-F Etard, E Delaporte
Ebola virus disease (EVD) epidemic that spread in West Africa from the end of 2013 to early 2016 has reached more people than all past epidemics. Beyond care management of acute phase ill patients and measures for the control of the epidemic, the outcome of Ebola survivors became an important question as their number increased and raised new issues. A multidisciplinary prospective cohort of survivors in Guinea has been launched by IRD UMI 233 and Donka National Hospital, Conakry, Guinea, to assess the long-term clinical, psychological, sociological, immunological, and viral outcomes potentially related to EVD...
October 2016: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/27557074/-incontinence-etiology-diagnostics-and-therapy
#4
Thomas Frieling
Fecal incontinence is defined by the unintentional loss of solid or liquid stool, and anal incontinence includes leakage of gas and / or fecal incontinence. Anal-fecal incontinence is not a diagnosis but a symptom. Many patients hide the problem from their families, friends, and even their doctors. Epidemiologic studies indicate a prevalence between 7-15 %, up to 30 % in hospitals and up to 70 % in longterm care settings. Anal-fecal incontinence causes a significant socio-economic burden. There is no widely accepted approach for classifying anal-fecal incontinence available...
August 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27397013/improving-treatment-adherence-in-heart-failure
#5
Susanne Unverzagt, Gabriele Meyer, Susanne Mittmann, Franziska-Antonia Samos, Malte Unverzagt, Roland Prondzinsky
BACKGROUND: Despite improved treatment options, heart failure remains the third most common cause of death in Germany and the most common reason for hospitalization. The treatment recommendations contained in the relevant guidelines have been incompletely applied in practice. The goal of this systematic review is to study the efficacy of adherence-promoting interventions for patients with heart failure with respect to the taking of medications, the implementation of recommended lifestyle changes, and the improvement in clinical endpoints...
June 24, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27284929/-whether-or-not-to-perform-an-early-endoscopy-following-ingestion-of-potentially-caustic-agents-a-retrospective-longterm-analysis-in-a-tertiary-referral-institution
#6
J M Gschossmann, R Schroeder, F Wyler, U Scheurer, U Schiemann
BACKGROUND: The optimal clinical management of patients following ingestion of potentially caustic lesions is still undetermined. In particular, the indication for early upper GI endoscopy in this context remains unclear. PURPOSE: To draft recommendations regarding the use of early upper GI endoscopy following hospital admissions of patients after ingestion of potentially caustic agents. METHODS: For this purpose, a retrospective cohort study of patients treated for ingestion of potentially caustic substances during a 13 year-period at the university hospital of Berne was performed...
June 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27206634/stability-of-remission-rates-in-a-3-year-follow-up-of-naturalistic-treated-depressed-inpatients
#7
Florian Seemüller, Michael Obermeier, Rebecca Schennach, Michael Bauer, Mazda Adli, Peter Brieger, Gerd Laux, Michael Riedel, Peter Falkai, Hans-Jürgen Möller
BACKGROUND: Remission is a common outcome of short-term trials and the main goal of acute and longterm treatment. The longitudinal stability of remission has rarely been investigated under naturalistic treatment conditions. METHODS: Naturalistic multisite follow-up study. Three-year symptomatic long-term outcome of initially hospitalized tertiary care patients (N = 784) with major depressive episodes. Remission rates as well as the switch rates between remission and non-remission were reported...
2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27033320/massage-for-low-back-pain
#8
Katrina Farber, L Susan Wieland
UNLABELLED: FURLAN AD, GIRALDOM, BASKWILL A, IRVIN E, IMAMURA M. MASSAGE FOR LOW-BACK PAIN. COCHRANE DATABASE SYST REV 2015, ISSUE 9. ART. NO.: CD001929. DOI: 10.1002/14651858.CD001929.PUB3. BACKGROUND: Low back pain (LPB) is one of the most common and costly musculoskeletal problems in modern society. It is experienced by 70-80% of adults at some time in their lives. Massage therapy has the potential to minimize pain and speed return to normal function. OBJECTIVES: To assess the effects of massage therapy for people with non-specific LBP...
May 2016: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/27004956/chronological-changes-of-quality-of-life-in-long-term-survivors-after-gastrectomy-for-gastric-cancer
#9
Wansik Yu, Ki Bum Park, Ho Young Chung, Oh Kyoung Kwon, Seung Soo Lee
PURPOSE: A few studies have prospectively evaluated changes in quality of life (QoL) after surgery in short-term survivors; however, no prospective study has evaluated the longitudinal changes in QoL in long-terms survivors. We prospectively evaluated the chronological changes in QoL after a gastrectomy over a 5-year postoperative period in a large group of patients. MATERIALS AND METHODS: QoL data from the European Organization for Research and Treatment of Cancer QLQ-C30 and the QLQ-STO22 questionnaires were obtained from 254 patients who completed the entire series of QoL assessments preoperatively and at 1, 2, 3, 4, and 5 years after surgery...
July 2016: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/26977634/deep-brain-stimulation-for-dystonia-review-of-the-literature
#10
Hubertus M Mehdorn
Deep brain stimulation (DBS) has become one of the major therapy options for movement disorders including dystonia. This article should give a review of the current literature from a neurosurgical perspective. Since dystonia is a rare disease, only few studies on larger cohorts have been published, and very few randomized controlled studies are avaialable in the international literature. Our experiences gained treating 134 patients with various types of dystonia, between 1999 and 2015, will serve a guide to interpret the current literature...
June 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/26664658/long-term-effect-of-optimized-sedation-and-pain-management-after-sudden-cardiac-arrest
#11
Nadine Abanador-Kamper, Judith Wolfertz, Petra Thürmann, Lars Kamper, Melchior Seyfarth
BACKGROUND AND AIMS: Appropriate use of sedatives and analgesics is essential to keep critically ill patients comfortable and to prevent prolonged mechanical ventilation time and length of stay in ICU. Aim of this study was to analyse the long-term effect of an algorithm-based individual analgesic-sedative protocol on mechanical ventilation time and ICU length of stay in critically ill patients after sudden cardiac arrest due to ST-elevated myocardial infarction. SUBJECT AND METHODS: We examined a total of 109 patients before and after implementation of an algorithm-based sedation management...
2015: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/26626118/considerations-on-caring-for-caregivers-in-an-aging-society
#12
Dr Samir K Sinha
While it is anticipated that healthcare systems around the world will continue to rely heavily on family members and friends to provide unpaid care especially to meet the needs of our aging population, current assumptions and issues around caregivers need to be challenged and addressed if we are to expect their future support. This paper builds on Williams et al's assertion that many current assumptions and issues around caregivers need to be challenged and addressed if we are to expect their future support...
2015: HealthcarePapers
https://www.readbyqxmd.com/read/26523046/verna-wright-lecture-psoriatic-arthritis-the-need-for-early-intervention
#13
Neil J McHugh
About 30% of individuals with skin psoriasis will develop an inflammatory disease of the peripheral or axial skeleton involving synovial and/or entheseal tissue termed psoriatic arthritis (PsA). In most cases psoriasis will precede PsA by several years. Hence skin psoriasis provides an opportune model to investigate genetic and environmental factors that interact and contribute to the development of a common form of inflammatory arthritis. Further, the preexisting presence of psoriasis represents a unique opportunity for the early detection of arthritis and the potential for more effective intervention...
November 2015: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/26489500/-treatment-of-chronic-lymphocytic-leukemia-with-tp53-aberrations
#14
D Lysák, J Schwarz
Patients with chronic lymphocytic leukemia with deletion of the short arm of chromosome 17 (17p -) or mutation of the TP53 gene have significantly worse prognosis with a higher risk of progression to symptomatic disease, worse and shorter responses to chemo immunotherapy, and more frequent occurrence of Richters syndrome. TP53 deletion/ mutation is currently the only genetic abnormality that independently predicts response to treatment and also affects the choice of therapeutic approach in chronic lymphocytic leukemia...
2015: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/26373873/survival-outcomes-in-liver-transplant-recipients-with-model-for-end-stage-liver-disease-scores-of-40-or-higher-a-decade-long-experience
#15
Hina J Panchal, Joel B Durinka, Jeromy Patterson, Farah Karipineni, Sarah Ashburn, Eric Siskind, Jorge Ortiz
BACKGROUND: The Model for End-stage Liver Disease (MELD) has been used as a prognostic tool since 2002 to predict pre-transplant mortality. Increasing proportions of transplant candidates with higher MELD scores, combined with improvements in transplant outcomes, mandate the need to study surgical outcomes in patients with MELD scores of ≥40. METHODS: A retrospective longitudinal analysis of United Network for Organ Sharing (UNOS) data on all liver transplantations performed between February 2002 and June 2011 (n = 33,398) stratified by MELD score (<30, 30-39, ≥40) was conducted...
December 2015: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/26370367/letter-by-cacko-et-al-regarding-article-improvement-of-cardiac-function-by-increasing-stimulus-strength-during-left-ventricular-pacing-in-cardiac-resynchronization-therapy
#16
LETTER
Andrzej Cacko, Marcin Michalak, Renata Główczyńska, Janusz Kochanowski, Marcin Grabowski
No abstract text is available yet for this article.
2015: International Heart Journal
https://www.readbyqxmd.com/read/26293854/findings-from-the-clinical-information-systems-perspective
#17
T Ganslandt, W O Hackl
OBJECTIVE: To summarize recent research and to propose a selection of best papers published in 2014 in the field of Clinical Information Systems (CIS). METHOD: A query with search terms from the Medical Subject Headings (MeSH) catalog as well as additional free text search terms was designed to identify relevant publications in the field of clinical information systems from PubMed and Web of Science®. The retrieved articles were then categorized in a multi-pass review carried out separately by the section editors...
August 13, 2015: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/26233513/an-observational-study-of-gout-prevalence-and-quality-of-care-in-a-national-australian-general-practice-population
#18
Philip C Robinson, William J Taylor, Nicola Dalbeth
OBJECTIVE: The central strategy for effective gout management is longterm urate-lowering therapy to maintain the serum urate at a level below 0.36 mmol/l. We sought to determine the prevalence of gout and the quality of care in a national Australian general practice population. METHODS: Data were from general practice point-of-care electronic records over a 5-year period (n = 1,479,449). Information was collected on patients with gout according to a validated definition...
September 2015: Journal of Rheumatology
https://www.readbyqxmd.com/read/26202627/atrial-fibrillation-screening-in-pharmacies-using-an-iphone-ecg-a-qualitative-review-of-implementation
#19
Nicole Lowres, Ines Krass, Lis Neubeck, Julie Redfern, Andrew J McLachlan, Alexandra A Bennett, S Ben Freedman
BACKGROUND: Atrial fibrillation guidelines advocate screening to identify undiagnosed atrial fibrillation. Community pharmacies may provide an opportunistic venue for such screening. OBJECTIVE: To explore the experience of implementing an atrial fibrillation screening service from the pharmacist's perspective including: the process of study implementation; the perceived benefits; the barriers and enablers; and the challenges for future sustainability of atrial fibrillation screening within pharmacies...
December 2015: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/26136487/outcome-of-patients-with-systemic-sclerosis-in-the-intensive-care-unit
#20
Frédéric Pène, Tarik Hissem, Alice Bérezné, Yannick Allanore, Guillaume Geri, Julien Charpentier, Jérôme Avouac, Loïc Guillevin, Alain Cariou, Jean-Daniel Chiche, Jean-Paul Mira, Luc Mouthon
OBJECTIVE: Patients with systemic sclerosis (SSc) are prone to disease-specific or treatment-related life-threatening complications that may warrant intensive care unit (ICU) admission. We assessed the characteristics and current outcome of patients with SSc admitted to the ICU. METHODS: We performed a single-center retrospective study over 6 years (November 2006-December 2012). All patients with SSc admitted to the ICU were enrolled. Short-term (in-ICU and in-hospital) and longterm (6-mo and 1-yr) mortality rates were studied, and the prognostic factors were analyzed...
August 2015: Journal of Rheumatology
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