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ultra running

F R Serpiello, W G Hopkins, S Barnes, J Tavrou, G M Duthie, R J Aughey, K Ball
The validity of an Ultra-wideband (UWB) positioning system was investigated during linear and change-of-direction (COD) running drills. Six recreationally-active men performed ten repetitions of four activities (walking, jogging, maximal acceleration, and 45º COD) on an indoor court. Activities were repeated twice, in the centre of the court and on the side. Participants wore a receiver tag (Clearsky T6, Catapult Sports) and two reflective markers placed on the tag to allow for comparisons with the criterion system (Vicon)...
December 1, 2017: Journal of Sports Sciences
Uwe Hans-Werner Schütz, Christian Billich, Daniel Schoss, Meinrad Beer, Jutta Ellermann
MR measurements can be accurately performed during 4486 km of running, opening a window into in vivo assessment of hindfoot articular cartilage under extreme ultra-endurance loading. This observational cross-sectional study included 22 randomized participants of TransEurope FootRace between Italy and the North Cape, which was accompanied by a trailer-mounted 1.5T MRI scanner over 9 weeks. Four follow up MR examinations of subtalar and midtarsal joints were performed. Statistics of cartilage T2*  and thickness were obtained...
November 30, 2017: International Journal of Sports Medicine
Zhaoguo Xue, Mei Sun, Taige Dong, Zhiqiang Tang, Yaolong Zhao, Junzhuan Wang, Xianlong Wei, Linwei Yu, Qing Chen, Jun Xu, Yi Shi, Kunji Chen, Pere Roca I Cabarrocas
Line-shape engineering is a key strategy to endow extra flexibility and stretchability to 1D silicon nanowires (SiNWs) grown with self-assembly processes. We here demonstrate a deterministic line-shape programming of in-plane SiNWs into extremely stretchable springs or arbitrary 2D patterns, with the aid of indium droplets that absorb amorphous Si precursor thin film to produce ultra-long c-Si NWs along programmed step edges. A reliable and faithful single run growth of c-SiNWs over turning tracks with different local curvatures has been well established, while high resolution transmission electron microscopy analysis reveals a high quality mono-like crystallinity in the line-shaped engineered SiNW springs...
November 30, 2017: Nano Letters
Gege Xu, Matthew J Amicucci, Zhi Cheng, Ace G Galermo, Carlito B Lebrilla
A rapid method for the quantitation of sixteen neutral and acidic monosaccharides, from both animal and plant sources was developed using ultra-high performance liquid chromatography triple quadrupole mass spectrometry (UHPLC/QqQ-MS) in dynamic multiple reaction monitoring (dMRM) mode. Monosaccharides including three pentoses (ribose, xylose, arabinose), two deoxyhexoses (rhamnose, fucose), five hexoses (fructose, mannose, allose, glucose, galactose), two hexuronic acids (glucuronic acid, galacturonic acid), and two N-acetyl-hexosamines (GlcNAc, GalNAc), were derivatized with 1-phenyl-3-methyl-5-pyrazolone (PMP), while underivatized sialic acids, Neu5Ac and Neu5Gc, were simultaneously analyzed with a 10-minute run...
November 29, 2017: Analyst
Shenghui Mei, Jiaqing Wang, Qing Cheng, Leting Zhu, Li Yang, Ruiling Chen, Zhigang Zhao
Norvancomycin (NVCM) is used in treating patients with infections caused by drug-resistant gram-positive bacteria. The NVCM plasma concentration varies greatly among individuals. To avoid the adverse drug reactions and prevent the presence of drug-resistant bacteria, the routine monitoring of NVCM in blood plasma was strongly recommended. However, there were few methods for plasma NVCM analysis. To the best of our knowledge, this is the first validated ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for plasma NVCM analysis...
November 21, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Zhihui Zhong, Sifeng Mao, Haifeng Lin, Jin-Ming Lin, Jianhua Lin
Osteosarcoma is the most common malignant tumour found in bones, and it has a poor prognosis. For improved therapy, it is significant to have a deep understanding of the proteomics changes in the cancer stem cells (CSCs) of osteosarcoma. Therefore, a comparative proteomics approach based on ultra-high-performance liquid chromatography coupled to an Orbitrap Fusion mass spectrometer (UHPLC-Orbitrap Fusion MS) was established to investigate the key molecular changes between CSCs and non-CSCs in human osteosarcoma HOS cells...
February 1, 2018: Talanta
Eloy Isarain-Chávez, Maria Dolors Baró, Eva Pellicer, Jordi Sort
Mesoporous Fe-Pt nodular films (with a regular spatial arrangement of sub-15 nm pores) are grown onto evaporated Au, Cu and Al conductive layers by micelle-assisted electrodeposition from metal chloride salts in the presence of Pluronic P123 tri-block copolymer dissolved in the aqueous electrolytic bath. This synthetic approach constitutes a simple, one-step, versatile procedure to grow multifunctional mesoporous layers appealing for diverse applications that take advantage of materials with an ultra-high surface area-to-volume ratio...
November 23, 2017: Nanoscale
Che-Hung Liu, Yen-Fang Tseng, Jiun-I Lai, Yin-Quan Chen, Shih-Hao Wang, Wei-Fong Kao, Li-Hua Li, Yu-Hui Chiu, Chorng-Kuang How, Wen-Han Chang
BACKGROUND: In endurance sports, stress, dehydration and release of chemical factors have been associated with red blood cell (RBC) alterations of structure and function, which may contribute to sports anemia, a well-observed phenomenon during long-distance running. Until now, the investigation of the changes of viscoelastic properties of RBC membrane, a decisive factor of RBC deformability to avoid hemolysis, is lacking, especially in an Oriental population. METHODS: nineteen runners were prospectively recruited into our study...
November 10, 2017: Journal of the Chinese Medical Association: JCMA
Teet Seene, Maria Umnova, Priit Kaasik
The aim of our research was to examine whether there are differences in the morphology of neuromuscular junctions of different types of muscle fibers in rodents, and after their adaptation to six weeks endurance exercise training. After 5-day acclimation, Wistar rats were subjected to run with the speed 35 m/min during 6 week, 5 days per week and the training volume reached 60 min per day. Muscle samples for ultrastructural studies were fixed, dehydrated and embedded in Epon-812. Ultra-thin sections were cut from longitudinally and transversely oriented blocs, using 4 blocks from each animal...
June 27, 2017: European Journal of Translational Myology
Xiaojing Huang, Shaomin Wang, Dan Mao, Shui Miao, Qing Hu, Shen Ji
In our study, a reliable and rapid analytical method for the simultaneous determination of 15 mycotoxins (aflatoxin B1, aflatoxin B₂, aflatoxin G1, aflatoxin G₂, alternariol, agroclavine, citrinin, diacetoxyscirpenol, deoxynivalenol, fumonisin B1, fumonisin B₂, ochratoxin A, sterigmatocystin, T-2 toxin, and zearalenone) in liquorice using ultra-HPLC coupled to tandem MS was developed and validated. Due to the complex ingredients in liquorice, we chose a QuEChERS-based extraction procedure as the sample pretreatment...
October 26, 2017: Journal of AOAC International
Noppon Taksaudom, Natee Tongsiri, Amarit Potikul, Chawakorn Leampriboon, Apichat Tantraworasin, Anong Chaiyasri
OBJECTIVE: Unique rough-terrain ultra-trail running races have increased in popularity. Concerns regarding the suitability of the candidates make it difficult for organizers to manage safety regulations. The purpose of this study was to identify possible race predictors and assess hemodynamic change after long endurance races. METHODS: We studied 228 runners who competed in a 66 km-trail running race. A questionnaire and noninvasive hemodynamic flow assessment including blood pressure, heart rate, stroke volume, stroke volume variation, systemic vascular resistance, cardiac index, and oxygen saturation were used to determine physiologic alterations and to identify finish predictors...
2017: Open Access Journal of Sports Medicine
Gianluca Vernillo, Grégoire P Millet, Guillaume Y Millet
No abstract text is available yet for this article.
2017: Frontiers in Physiology
Caroline Chipeaux, Marine de Person, Nathalie Burguet, Thierry Billette de Villemeur, Christian Rose, Nadia Belmatoug, Sylvie Héron, Caroline Le Van Kim, Mélanie Franco, Fathi Moussa
While important advances have been recently achieved in the optimization of lipid classes' separation, information on the specific determination of medium polarity lipids such as sphingolipids (SLs) in highly complex matrices remains fragmentary. In human, disorders of SL metabolism known as sphingolipidoses are a heterogeneous group of inherited disorders affecting primarily the central nervous. Early diagnosis of these conditions is of importance notably when a corrective therapy is available. The diagnosis is generally based on the determination of specific SLs in plasma and red blood cells (RBCs)...
October 14, 2017: Journal of Chromatography. A
Danti Mai, Chan Yang, Yun Xue, Yan Wang, Chao Yan
The objective of this research is to investigate the suppressive effect of silymarin on vitro cell culture model of inflammatory macrophage RAW264.7 induced by Kdo2-Lipid A, and explore its mechanism based on cell metabonomics. Ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) method was used in the cell metabonomic assay to quantitative analysis of metabolites related to eicosanoids pathway. Then chemometric approaches such as principal component analysis were used to process the metabolic data...
June 8, 2017: Se Pu, Chinese Journal of Chromatography
Yufang Zheng, Erik Sparve, Mats Bergström
BACKGROUND: Oral fluid sampling offers several advantages compared to other methods of detecting drugs in biological matrices due to its easy sampling procedure and simple supervision. Hence, the use of oral fluid for drug testing is increasing in workplaces and in roadside testing. As a result, more laboratories are required to perform analyses of drugs in oral fluid. METHODS: A multi-method using Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) for tracing drugs in oral fluid was developed...
October 16, 2017: Drug Testing and Analysis
Folker Meyer, Saurabh Bagchi, Somali Chaterji, Wolfgang Gerlach, Ananth Grama, Travis Harrison, Tobias Paczian, William L Trimble, Andreas Wilke
As technologies change, MG-RAST is adapting. Newly available software is being included to improve accuracy and performance. As a computational service constantly running large volume scientific workflows, MG-RAST is the right location to perform benchmarking and implement algorithmic or platform improvements, in many cases involving trade-offs between specificity, sensitivity and run-time cost. The work in [Glass EM, Dribinsky Y, Yilmaz P, et al. ISME J 2014;8:1-3] is an example; we use existing well-studied data sets as gold standards representing different environments and different technologies to evaluate any changes to the pipeline...
September 26, 2017: Briefings in Bioinformatics
Deep Dutta, Meha Sharma, Rahul Bansal, Neera Sharma, Umesh Chandra Garga, Atul Anand, Kumar Gaurav
INTRODUCTION: This study evaluated prevalence and predictors of osteoporosis and sarcopenia in men with HIV. MATERIAL AND METHODS: 220 men with HIV were screened, of which 115 men, 30-50 years-age, having at least 1-year follow-up, underwent hormonal and DEXA analysis. 40 controls were also evaluated. RESULTS: Males with HIV had significantly lower BMD and Z-scores at all sites. Osteoporosis was diagnosed in 64.35%; commonest site being radius total (49...
October 12, 2017: Endokrynologia Polska
Philip Ls Tan, Frankie Hy Tan, Andrew N Bosch
This study aimed to compare and determine the differences in the physiological, anthropometric and training characteristics of the finishers (FIN) and non-finishers (N-FIN) in a 161-km race. Two groups of runners (FIN; N=12 and N-FIN; N=14) completed a series of anthropometric and physiological measurements over two separate sessions at least three weeks prior to the race. Training sessions starting from six weeks prior to the race were recorded. Sum of 7 skinfolds, arm and calf girths, VO2max and peak treadmill speed (PTS) were taken during session 1 while the lactate threshold (LT) and running economy (RE) were assessed during session 2...
2017: International Journal of Exercise Science
Leo W Y Yeung, Christopher Stadey, Scott A Mabury
An analytical method using ultra performance convergence chromatography (UPC(2)) coupled to a tandem mass spectrometer operated in negative electrospray mode was developed to measure perfluoroalkyl and polyfluoroalkyl substances (PFASs) including the ultrashort-chain PFASs (C2-C3). Compared to the existing liquid chromatography tandem mass spectrometry method using an ion exchange column, the new method has a lower detection limit (0.4pg trifluoroacetate (TFA) on-column), narrower peak width (3-6s), and a shorter run time (8min)...
September 23, 2017: Journal of Chromatography. A
Marthe De Boevre, Christof Van Poucke, Emmanuel Njumbe Ediage, Dana Vanderputten, Anita Van Landschoot, Sarah De Saeger
A simple, reliable method for the detection of free and modified Fusarium mycotoxins in beer using state-of-the-art ultra-high-performance supercritical fluid chromatography (UHPSFC) with low-resolution tandem MS (MS/MS) is presented in this paper. The UHPSFC-MS/MS method was developed for nivalenol, deoxynivalenol, 15-acetyl-deoxynivalenol, 3-acetyl-deoxynivalenol, deoxynivalenol-3-glucoside, HT-2 toxin, T-2 toxin, T-2 toxin-3-glucoside, neosolaniol, diacetoxyscirpenol, zearalenone, α-zearalenol, and β-zearalenol and their internal standards deepoxy-deoxynivalenol and zearalanone...
October 2, 2017: Journal of AOAC International
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