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https://www.readbyqxmd.com/read/28633561/regulation-of-energy-homeostasis-after-gastric-bypass-surgery
#1
Martin L Yarmush, Matthew D'Alessandro, Nima Saeidi
The obesity epidemic continues to escalate each year in the United States more than anywhere else in the world. The existing pharmaceutical and other nonsurgical treatments for morbid obesity produce suboptimal physiologic outcomes compared with those of Roux-en-Y gastric bypass (RYGB) surgery. RYGB has been the gold standard of bariatric surgery because the beneficial long-term outcomes, which include sustainable weight loss and type 2 diabetes mellitus (T2DM) resolution, are far superior to those obtained with other bariatric surgeries...
June 21, 2017: Annual Review of Biomedical Engineering
https://www.readbyqxmd.com/read/28623447/new-approaches-to-gastroesophageal-reflux-disease
#2
William Kethman, Mary Hawn
BACKGROUND: Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disorder of the esophagus. It is a chronic, progressive disorder that presents most typically with heartburn and regurgitation and atypically with chest pain, dysphagia, chronic cough, globus, or sore throat. The mainstay for diagnosis and characterization of the disorder is esophagoduodenoscopy (EGD), high-resolution esophageal manometry, and symptom-associated ambulatory esophageal pH impedance monitoring...
June 16, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28602794/long-term-outcome-of-laparoscopic-adjustable-gastric-banding-lagb-results-of-a-swiss-single-center-study-of-405-patients-with-up-to-18-years-follow-up
#3
Fabrizio Vinzens, Ashley Kilchenmann, Valentin Zumstein, Marc Slawik, Martina Gebhart, Ralph Peterli
BACKGROUND: In the past, laparoscopic adjustable gastric banding (LAGB) seemed to be a promising bariatric procedure. However, many studies showed high rates of reoperation due to complications or insufficient weight loss. There is a lack of long-term studies with follow-up beyond 15 years. OBJECTIVE: To conduct long-term follow-up of patients after LAGB and analyze their weight loss as a primary endpoint. SETTING: Tertiary referral center for bariatric surgery, St...
April 29, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28600114/conversion-of-failed-roux-en-y-gastric-bypass-to-biliopancreatic-diversion-with-duodenal-switch-outcomes-of-9-case-series
#4
Hamzeh M Halawani, Fernando Bonanni, Abraham Betancourt, Gintaras Antanavicius
INTRODUCTION: Weight regain after Roux-en-Y gastric bypass (RYGB) is a frustrating long-term complication in some patients. Revision of RYGB to biliopancreatic diversion with duodenal switch (BPD-DS) is an appealing option. There is a paucity of information in literature regarding this type of conversion. SETTING: Regional referral center and teaching hospital, Pennsylvania, United States; nonprofit. METHODS: Between 2013 and 2016, a retrospective chart review was performed on all our revision cases...
April 26, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28584299/dissociation-of-body-mass-index-excess-weight-loss-and-body-fat-percentage-trajectories-after-3-years-of-gastric-bypass-relationship-with-metabolic-outcomes
#5
J Gómez-Ambrosi, P Andrada, V Valentí, F Rotellar, C Silva, V Catalán, A Rodríguez, B Ramírez, R Moncada, J Escalada, J Salvador, G Frühbeck
BACKGROUND/OBJECTIVES: Body weight, body mass index (BMI) and excess weight loss (EWL) are the most frequently used measures to analyse bariatric surgery outcomes. However, these measurements do not provide accurate information on body composition (BC) with body fat (BF) importantly determining the levels of cardiometabolic risk factors. Our aim was to analyse the evolution of BC after Roux-en-Y Gastric Bypass (RYGB) and its influence on the changes of cardiometabolic risk factors in comparison to BMI and EWL...
June 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28583814/prospectively-validated-preoperative-prediction-of-weight-and-co-morbidity-resolution-in-individual-patients-comparing-five-bariatric-operations
#6
Gus J Slotman
BACKGROUND: No method preoperatively predicts the postoperative bariatric surgery outcomes in individual patients. Decisions for or against surgery and operation choice remain subjective. Only 1% of qualifying patients embrace bariatric surgery. OBJECTIVE: To predict preoperatively and validate prospectively the weight and co-morbidity resolution in individual patients after open Roux-en-Y gastric bypass (RYGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB), laparoscopic adjustable gastric band (LAGB), sleeve gastrectomy (SG), and biliopancreatic diversion/duodenal switch (BPD/DS)...
April 15, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28576682/bile-reflux-of-the-remnant-stomach-following-roux-en-y-gastric-bypass-an-etiology-of-chronic-abdominal-pain-treated-with-remnant-gastrectomy
#7
Erika La Vella, Zach Hovorka, Donald E Yarbrough, Elizabeth McQuitty
BACKGROUND: Bile reflux gastritis of the remnant stomach following Roux-en-Y gastric bypass (RYGB) causing chronic abdominal pain has not been reported. We report a series of symptomatic patients with remnant gastritis treated effectively with remnant gastrectomy (RG). OBJECTIVE: The objective was to report our experience with bile reflux remnant gastritis after RYGB and our outcomes following RG. SETTING: Community teaching hospital. METHODS: All patients undergoing RG were retrospectively reviewed for presenting symptoms, diagnostic workup, pathology, complications, and symptom resolution...
April 15, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28573535/long-term-outcome-of-bariatric-surgery-in-morbidly-obese-adolescents-a-systematic-review-and-meta-analysis-of-950-patients-with-a-minimum-of-3%C3%A2-years-follow-up
#8
Saeed Shoar, Habibollah Mahmoudzadeh, Mohammad Naderan, Shahram Bagheri-Hariri, Catherine Wong, Ahmad Shahabeddin Parizi, Nasrin Shoar
BACKGROUND: Obesity in pediatric and adolescent population has reached a universal pandemic. This study aimed to summarize the literature on the longest available outcome of bariatric surgery in morbidly obese adolescents. METHODS: A systematic review was conducted to pool available data on the longest available (>3 years) weight loss and comorbidity resolution outcome in adolescent bariatric surgery. RESULTS: A total of 14 studies reporting the result of bariatric surgery after 3 years in 950 morbidly obese adolescents were included...
June 2, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28569358/revision-procedures-after-failed-adjustable-gastric-banding-comparison-of-efficacy-and-safety
#9
Pawan Chansaenroj, Lwin Aung, Wei-Jei Lee, Shu Chun Chen, Jung-Chien Chen, Kong-Han Ser
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) was one of the commonly performed bariatric operations; however, it carries a high revision rate. The aim of the present study was to report the long-term outcomes of LAGB and compare the outcomes between the different revision procedures. METHODS: All patients who underwent LAGB in a large bariatric center in Asia between May 2002 and April 2011 were included. Interval between primary LAGB to the revision operation, the reason and type of revision surgery were identified and analyzed...
May 31, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28567337/body-mass-index-is-associated-with-region-dependent-metabolic-reprogramming-of-adipose-tissue
#10
Marco G Alves, Ângela Moreira, Marta Guimarães, Mário Nora, Mario Sousa, Pedro F Oliveira, Mariana P Monteiro
Adipose tissue (AT) is involved in dysmetabolism pathogenesis. Regional fat distribution and functioning may contribute to obesity-related metabolic disorders and adverse health outcomes. Specific fat depots are suggested to possess unique biological properties, but specific metabolic profiles of subcutaneous (SAT) and visceral adipose tissue (VAT) remain unknown. We aimed to characterize VAT and SAT glucose metabolism, and their correlation with body mass index (BMI). AT samples from patients (n = 12; F:M, 9:3) with a mean age of 46 years (26-83 years) and an average BMI of 29...
December 2017: BBA Clinical
https://www.readbyqxmd.com/read/28552743/-candy-cane-syndrome-an-underappreciated-cause-of-abdominal-pain-and-nausea-after-roux-en-y-gastric-bypass-surgery
#11
Amir H Aryaie, Mojtaba Fayezizadeh, Yuxiang Wen, Mohammed Alshehri, Mujjahid Abbas, Leena Khaitan
BACKGROUND: "Candy cane" syndrome (a blind afferent Roux limb at the gastrojejunostomy) has been implicated as a cause of abdominal pain, nausea, and emesis after Roux-n-Y gastric bypass (RYGB) but remains poorly described. OBJECTIVES: To report that "candy cane" syndrome is real and can be treated effectively with revisional bariatric surgery SETTING: All patients underwent "candy cane" resection at University Hospitals of Cleveland. METHODS: All patients who underwent resection of the "candy cane" between January 2011 and July 2015 were included...
April 8, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28549834/obstructive-sleep-apnea-the-effect-of-bariatric-surgery-after-12%C3%A2-months-a-prospective-multicenter-trial
#12
P Peromaa-Haavisto, H Tuomilehto, J Kössi, J Virtanen, M Luostarinen, J Pihlajamäki, P Käkelä, M Victorzon
BACKGROUND: Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder, particularly in bariatric patients. It is known to be tightly linked with metabolic abnormalities and cardiovascular morbidity. Obesity is the most noteworthy individual risk factor for OSA. The aim of this study was to investigate the effect of a laparoscopic Roux-en-Y gastric bypass (LRYGB) on OSA one year after surgery. METHODS: In this prospective multicenter study standard overnight cardiorespiratory recording was conducted 12 months after bariatric surgery in 132 patients who had OSA in the baseline recording prior to the operation...
July 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28545917/comparison-of-oral-antibiotic-failure-rates-in-post-roux-en-y-gastric-bypass-patients-versus-controls
#13
David J Roy, Diana R Langworthy, Kristina M Thurber, Paul A Lorentz, Ross A Dierkhising, Manpreet S Mundi
BACKGROUND: Due to the malabsorptive nature of the Roux-en-Y gastric bypass (RYGB), there is a potential for impaired absorption of oral medications. Clinical outcomes of patients who receive oral antibiotics after RYGB have not been adequately described in the literature. OBJECTIVES: The primary objective was composite therapeutic failure. Secondary objectives included comparing failure rates between antibiotic classes and at various time points since RYGB. SETTING: University hospital, United States...
March 29, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28534188/outcomes-of-one-anastomosis-gastric-bypass-in-472-diabetic-patients
#14
Osama Taha, Mahmoud Abdelaal, Mohamed Abozeid, Awny Askalany, Mohamed Alaa
BACKGROUND: The positive impact of Roux-en-Y gastric bypass (RYGB) on metabolic syndrome and glycemic control has been proven in obese patients. One anastomosis gastric bypass (OAGB) is a simple, effective and easy to learn procedure. OAGB provides encouraging results for the treatment of diabetes obese patients, but does it have the ability to be an alternative procedure to RYGB in the treatment of these patients? The aim of this study is to evaluate the outcomes of OAGB on diabetic obese patients at the bariatric centre of our university hospital...
May 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28532499/laparoscopic-roux-en-y-gastric-bypass-versus-laparoscopic-mini-gastric-bypass-in-the-treatment-of-obesity-study-protocol-for-a-randomized-controlled-trial
#15
Marko Kraljević, Tarik Delko, Thomas Köstler, Elena Osto, Thomas Lutz, Sarah Thommen, Raoul A Droeser, Lincoln Rothwell, Daniel Oertli, Urs Zingg
BACKGROUND: Laparoscopic Roux-en-Y gastric bypass (LRYGB) is considered the gold standard in bariatric surgery, achieving durable long-term weight loss with improvement of obesity-related comorbidities. Lately, the laparoscopic mini gastric bypass (LMGB) has gained worldwide popularity with similar results to LRYGB in terms of weight loss and comorbidity resolution. However, there is a lack of randomized controlled trials (RCT) comparing LMGB and LRYGB. This article describes the design and protocol of a randomized controlled trial comparing the outcomes of these two bariatric procedures...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28528115/alcohol-and-other-substance-use-after-bariatric-surgery-prospective-evidence-from-a-u-s-multicenter-cohort-study
#16
Wendy C King, Jia-Yuh Chen, Anita P Courcoulas, Gregory F Dakin, Scott G Engel, David R Flum, Marcelo W Hinojosa, Melissa A Kalarchian, Samer G Mattar, James E Mitchell, Alfons Pomp, Walter J Pories, Kristine J Steffen, Gretchen E White, Bruce M Wolfe, Susan Z Yanovski
BACKGROUND: Empirical evidence suggests Roux-en-Y gastric bypass (RYGB) increases risk of developing alcohol use disorder (AUD). However, prospective assessment of substance use disorders (SUD) after bariatric surgery is limited. OBJECTIVE: To report SUD-related outcomes after RYGB and laparoscopic adjustable gastric banding (LAGB). To identify factors associated with incident SUD-related outcomes. SETTING: 10 U.S. hospitals METHODS: The Longitudinal Assessment of Bariatric Surgery-2 is a prospective cohort study...
March 31, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28514487/reoperation-and-medicare-expenditures-after-laparoscopic-gastric-band-surgery
#17
Andrew M Ibrahim, Jyothi R Thumma, Justin B Dimick
Importance: Following the US Food and Drug Administration approval for laparoscopic gastric band surgery in 2001, as many as 96 000 devices have been placed annually. The reported rates of reoperation range from 4% to 60% in short-term studies; however, to our knowledge, few long-term population-level data on outcomes or expenditures are known. Objective: To describe the rate of device-related reoperations occurring after laparoscopic gastric band surgery as well as the associated payments in a longitudinal national cohort...
May 17, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28501321/the-effect-of-close-postoperative-follow-up-on-co-morbidity-improvement-after-bariatric-surgery
#18
Andrea Schwoerer, Kevin Kasten, Adam Celio, Walter Pories, Konstantinos Spaniolas
BACKGROUND: Patients undergoing gastric bypass (RYGB) surgery require follow-up for efficacy assessment, early detection of postoperative complications, and also for management of co-morbid conditions. Recent literature shows support for improved long-term weight loss with close patient follow-up. However, attrition rates after RYGB have been reported as high as 50%. OBJECTIVE: The objective of this study was to assess the relationship between complete follow-up and improvement or remission of co-morbid conditions at 12 months after surgery...
March 28, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28500419/bariatric-surgery-as-a-bridge-to-renal-transplantation-in-patients-with-end-stage-renal-disease
#19
Shadi Al-Bahri, Tannous K Fakhry, John Paul Gonzalvo, Michel M Murr
BACKGROUND: Obesity is a relative contraindication to organ transplantation. Preliminary reports suggest that bariatric surgery may be used as a bridge to transplantation in patients who are not eligible for transplantation because of morbid obesity. SETTING: The Bariatric Center at Tampa General Hospital, University of South Florida, Tampa, Florida. METHODS: We reviewed the outcomes of 16 consecutive patients on hemodialysis for end-stage renal disease (ESRD) who underwent bariatric surgery from 1998 to 2016...
May 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28493043/revisional-surgery-after-failed-laparoscopic-sleeve-gastrectomy-retrospective-analysis-of-causes-results-and-technical-considerations
#20
Huseyin Yilmaz, Ilhan Ece, Mustafa Sahin
BACKGROUND: A failed laparoscopic sleeve gastrectomy (LSG) presents a challenging problem for bariatric surgeons. The aim of this study was to evaluate the indications, treatment strategies, and surgical outcomes of patients who underwent a revisional surgery after a failed LSG. METHODS: This retrospective study included the outcomes of 32 patients who required a revisional surgery from a series of 500 primary LSGs. The patients' demographic data, indications for revisional surgery, perioperative complications, and postoperative outcomes were recorded...
May 10, 2017: Obesity Surgery
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