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https://www.readbyqxmd.com/read/28922332/evaluation-of-corneal-neovascularization-using-optical-coherence-tomography-angiography-in-patients-with-limbal-stem-cell-deficiency
#1
Yoshinori Oie, Kohji Nishida
PURPOSE: Detection of the exact area of corneal neovascularization using slit-lamp photography is often difficult. Thus, we evaluated corneal neovascularization in patients with limbal stem cell deficiency using optical coherence tomography angiography (OCTA). METHODS: Five patients with 5 eyes showing partial or total limbal stem cell deficiency were enrolled. Three eyes had severe corneal scarring. Five 6- × 6-mm images (frontal, upper, lower, nasal, and temporal) were obtained by OCTA...
September 14, 2017: Cornea
https://www.readbyqxmd.com/read/28922018/tacrolimus-ointment-for-refractory-posterior-blepharitis
#2
Fernando Eiji Sakassegawa-Naves, Helena Maria Moraes Ricci, Bernardo Kaplan Moscovici, Daniela Akemi Miyamoto, Brenda Biagio Chiacchio, Ricardo Holzchuh, Ruth Muyuki Santo, Richard Yudi Hida
PURPOSE: This prospective, randomized, double-blind interventional case series was designed to evaluate the short-term efficacy of 0.03% tacrolimus ointment as a new therapeutic approach for refractory cases of posterior blepharitis. METHODS: Forty eyes (20 patients) with posterior blepharitis refractory to previous treatment were randomized. Eighteen eyes (9 patients) were treated with 0.03% tacrolimus ointment and 20 eyes (10 patients) with placebo ointment twice daily...
September 18, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28920812/ophthalmic-examination-in-common-kestrels-falco-tinnuculus-from-south-korea
#3
Jury Kim, Daeyoung Kim, Eun-Ju Kim, Hae-Beom Lee, Nam-Soo Kim, Min-Su Kim
The purpose of this study was to establish reference ophthalmic findings in the common kestrel (Falco tinnunculus). Twenty healthy adult kestrels were included in this study. Ophthalmic examinations included slit lamp biomicroscopy, fundus exam, Schirmer tear test, conjunctival bacterial culture and isolation, corneal touch threshold, tonometry, and corneal diameter measurement. Mean tear production was 7.4 ± 3.27 mm/min, and mean intraocular pressure measured via applanation tonometry was 10.5 ± 3.15 mm Hg...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28920794/intraocular-pressure-and-examination-findings-in-three-species-of-central-and-south-american-tree-frogs-cruziohyla-craspedopus-cruziohyla-calcarifer-and-anotheca-spinosa
#4
Andrew C Lewin, Jennifer C Hausmann, Paul E Miller
The purpose of this prospective study was to describe intraocular pressure (IOP) and examination findings in three tree frog species (Cruziohyla craspedopus [fringe leaf frog], Cruziohyla calcarifer [splendid leaf frog], and Anotheca spinosa [spiny-headed or coronated tree frog]). Thirty-one C. craspedopus, four C. calcarifer, and five A. spinosa were weighed, sexed based on phenotype where possible, and examined using slit-lamp biomicroscopy and indirect ophthalmoscopy. IOP was measured using the TonoVet and TonoLab rebound tonometers while the frogs were held two ways (unrestrained, then restrained)...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28917477/using-a-slit-knife-to-facilitate-mohs-micrographic-surgery-in-irregularly-shaped-areas
#5
José Francisco Millán-Cayetano, Inés Fernández-Canedo, Alberto Ortega-Sánchez, Magdalena de Troya-Martín
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28914793/multi-aperture-shower-design-for-the-improvement-of-the-transverse-uniformity-of-mocvd-derived-gdybco-films
#6
Ruipeng Zhao, Qing Liu, Yudong Xia, Fei Zhang, Yuming Lu, Chuanbing Cai, Bowan Tao, Yanrong Li
A multi-aperture shower design is reported to improve the transverse uniformity of GdYBCO superconducting films on the template of sputtered-LaMnO₃/epitaxial-MgO/IBAD-MgO/solution deposition planarization (SDP)-Y₂O₃-buffered Hastelloy tapes. The GdYBCO films were prepared by the metal organic chemical vapor deposition (MOCVD) process. The transverse uniformities of structure, morphology, thickness, and performance were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), step profiler, and the standard four-probe method using the criteria of 1 μV/cm, respectively...
September 15, 2017: Materials
https://www.readbyqxmd.com/read/28914060/nuclear-spin-symmetry-conservation-in-1-h2-16-o-investigated-by-direct-absorption-ftir-spectroscopy-of-water-vapor-cooled-down-in-supersonic-expansion
#7
Robert Georges, Xavier Michaut, Audrey Moudens, Manuel Goubet, Olivier Pirali, Pascale Soulard, Pierre Asselin, Therese R Huet, Pascale Roy, Martin Fournier, Andrey A Vigasin
We report the results of an experimental study related to the relaxation of the nuclear spin isomers of the water molecule in a supersonic expansion. Rovibrational lines of both ortho- and para- spin isomers were recorded in the spectral range of H2O stretching vibrations around 3700 cm(-1) using FTIR direct absorption. Water vapor seeded either in argon, helium, oxygen or in a mixture of oxygen and argon was expanded into vacuum through a slit nozzle. Partial water vapor pressure in the mixture varied in a wide range from 1...
September 15, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28913510/the-prevalence-and-determinants-of-pterygium-in-rural-areas
#8
Hassan Hashemi, Mehdi Khabazkhoob, Abbasali Yekta, Ebrahim Jafarzadehpour, Hadi Ostadimoghaddam, Haleh Kangari
PURPOSE: To evaluate the prevalence of pterygium and its determinants in the underserved, rural population of Iran. METHODS: In this cross-sectional study of 3851 selected individuals, 86.5% participated in the study, and the prevalence of pterygium was evaluated in 3312 participants. A number of villages were selected from the north and south of Iran using multistage cluster sampling. Pterygium was diagnosed by the ophthalmologist using slit-lamp examination. RESULTS: The mean age of the study participants was 37...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28912992/giant-conjunctival-nevus-in-a-12-year-old-child
#9
Edit Tóth-Molnár, Eszter Vizvári, Ákos Skribek, András Vörös
We describe a case of a giant conjunctival nevus presented in a 12-year-old girl with suspicious clinicomorphological appearance. The lesion was noticed by the parents at the age of 3 years as a "fleshy spot" on the bulbar conjunctiva. The lesion remained unchanged until approx. 6 months before recent admission. On slit-lamp examination, a large conjunctival lesion with variegate pigmentation and indistinct margins was detected on the superonasal part of the bulbar conjunctiva of the left eye. Intralesional cysts and vessels were detected with AS-OCT examination...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28912848/changes-in-the-anterior-cornea-during-the-early-stages-of-severe-myopia-prior-to-and-following-lasik-as-detected-by-confocal-microscopy
#10
Jinrong Zhao, Jinguo Yu, Liu Υang, Yang Liu, Shaozhen Zhao
The present study aimed to assess the microscopic changes of the epithelium and Bowman's layer under confocal microscopy during the early stages of severe myopia following laser in situ keratomileusis (LASIK). The study comprised 54 patients (54 eyes) with severe myopia and 65 patients (65 eyes) with low and moderate myopia, who underwent LASIK surgery at Tianjin Medical University Eye Hospital (Tianjin, China). In all patients, the epithelium, Bowman's layer and anterior stroma were examined prior to and 1, 7, 30, 90 and 180 days after the surgery, using in vivo confocal microscopy...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28912560/the-srgap2-snps-their-haplotypes-and-g%C3%A2-%C3%A3-%C3%A2-e-interactions-on-serum-lipid-traits
#11
Liu Miao, Rui-Xing Yin, Jin-Zhen Wu, Shuo Yang, Wei-Xiong Lin, Shang-Ling Pan
Maonan nationality is a relatively conservative and isolated minority in China. Little is known about the association of the Slit-Robo Rho GTPase activating protein 2 gene (SRGAP2) single nucleotide polymorphisms (SNPs) and serum lipid levels in the Chinese populations. This study was performed to clarify the association of the SRGAP2 rs2483058 and rs2580520 SNPs and their haplotypes with serum lipid traits in the Maonan and Han populations. Genotyping of the 2 SNPs was performed in 2444 unrelated subjects (Han, 1210 and Maonan, 1234) by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis, and then confirmed by direct sequencing...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28911992/is-corneal-arcus-independently-associated-with-incident-cardiovascular-disease-in-asians
#12
Mark Yu Zheng Wong, Ryan Eyn Kidd Man, Preeti Gupta, Sing Hui Lim, Blanche Lim, Yih-Chung Tham, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux
PURPOSE: To examine the longitudinal relationship between baseline corneal arcus (CA) and incident CVD in ethnic Indian and Malay adults in Singapore. DESIGN: Population-based cohort study. METHODS: Indian and Malay adults aged 40-80 years were recruited for baseline and 6-year follow-up visits between 2004-09 and 2010-15, respectively (follow-up response rate 73.9%). CA was assessed by ophthalmologists using slit-lamp biomicroscopy. The main outcome was self-reported incident CVD, defined as new myocardial infarction, angina pectoris or stroke, which developed between baseline and follow-up...
September 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28911971/the-effects-of-house-dust-mite-sublingual-immunotherapy-slit-tablet-effects-on-immunological-biomarkers-and-nasal-allergen-challenge-symptoms
#13
Natasha C Gunawardana, Qing Zhao, Leonidas N Carayannopoulos, Kuenhi Tsai, Vladislav A Malkov, Diana Selverian, Graham Clarke, Tim Mant, Brent Butts, Kaare Lund, Trevor T Hansel, Hendrik Nolte
SQ HDM SLIT-tablet significantly increased serum HDM-specific IgG4 and IgE blocking factor, and significantly decreased early phase nasal symptoms after nasal allergen challenge. No significant effects on cytokines or gene expression in nasal mucosa were observed.
September 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28910534/pressure-enhancement-in-confined-fluids-effect-of-molecular-shape-and-fluid-wall-interactions
#14
Deepti Srivastava, Erik Santiso, Keith E Gubbins
Recently, several experimental and simulation studies have found that phenomena that normally occur at extremely high pressures in a bulk phase can occur in nano-phases confined within porous materials at much lower bulk phase pressures, thus providing an alternative route to study high-pressure phenomena. In this work, we examine the effect on the tangential pressure of varying the molecular shape, strength of the fluid-wall interactions, and pore width, for carbon slit-shaped pores. We find that, for multi-site molecules, the presence of additional rotational degrees of freedom leads to unique changes in the shape of the tangential pressure profile, especially in larger pores...
September 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28910175/neurotrophic-keratopathy-therapeutic-approach-using-a-novel-matrix-regenerating-agent
#15
Marta Guerra, Sara Marques, João Quadrado Gil, Joana Campos, Paula Ramos, Andreia Martins Rosa, Maria João Quadrado, Joaquim Neto Murta
PURPOSE: To evaluate the efficacy and tolerance of a new matrix-regenerating agent (RGTA), Cacicol(®), a polymer that mimics heparan sulfates bound to extracellular matrix proteins, avoiding its proteolysis, to treat neurotrophic keratopathy (NK). METHODS: Uncontrolled prospective clinical study performed between January 2014 and May 2016. Twenty-five patients (25 eyes) with corneal neurotrophic ulcers, nonresponsive to at least 2 weeks of conservative therapy, were treated with Cacicol, instilled once/twice a week...
September 14, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28906020/diagnostic-impact-of-anterior-segment-angiography-of-limbal-stem-cell-insufficiency-in-pax6-related-aniridia
#16
Barbara Käsmann-Kellner, Lorenz Latta, Fabian Fries, Arne Viestenz, Berthold Seitz
BACKGROUND: PAX6 is a master gene of ocular development and postnatal ocular equilibrium. Congenital aniridia is the hallmark of PAX6 gene haploinsufficiency (Chr. 11 p. 13), but PAX6-associated aniridia is a profound, progressive pan-ocular developmental disorder often leading to blindness. Limbal stem cell insufficiency and corneal findings in PAX6 syndrome: There is congenital visual impairment with advancing loss of vision mainly due to secondary glaucoma and to corneal blindness caused by limbal stem cell insufficiency (LSCI)...
September 14, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28905834/microsporidial-infection-masquerading-as-graft-rejection-post-descemet-s-stripping-automated-endothelial-keratoplasty
#17
Lumbini Devi, N Venkatesh Prajna, Muthiah Srinivasan, Naveen Radhakrishnan, Manoranjan Das
A 51-year-old immunocompetent male with a history of Fuchs' endothelial dystrophy and immature cataract who underwent Descemet's stripping automated endothelial keratoplasty with intraocular lens implantation in both eyes presented with redness and defective vision of 1-day duration in his left eye. Slit lamp examination revealed coarse superficial punctate lesions with graft edema. He was diagnosed with acute graft rejection and treated with topical steroids. Two days later, symptoms worsened in his left eye with the involvement of his right eye showing a similar clinical picture...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905674/angioleiomyoma-of-uterus-a-clinicopathologic-study-of-6-cases
#18
Mayank Gupta, Mayur Suryawanshi, Ramani Kumar, Abraham Peedicayil
BACKGROUND AND OBJECTIVES: Angioleiomyoma is a benign perivascular neoplasm commonly involving subcutaneous tissue of extremities, head, and trunk region. They rarely involve the female genital tract. This study analyses clinicopathological features of 6 cases of uterine angioleiomyoma. METHODS: Routine sections of 6 cases were reviewed and immunohistochemical markers namely muscle-specific actin, h-caldesmon, desmin, CD10, WT-1, HMB-45, and melan-A were done. RESULTS: Of the 6 cases, 4 cases had tumor involving the corpus and 2 cases had tumor in the cervix...
September 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28904359/structured-illumination-microscopy-and-automatized-image-processing-as-a-rapid-diagnostic-tool-for-podocyte-effacement
#19
Florian Siegerist, Silvia Ribback, Frank Dombrowski, Kerstin Amann, Uwe Zimmermann, Karlhans Endlich, Nicole Endlich
The morphology of podocyte foot processes is obligatory for renal function. Here we describe a method for the superresolution-visualization of podocyte foot processes using structured illumination microscopy of the slit diaphragm, which before has only been achieved by electron microscopy. As a proof of principle, we measured a mean foot process width of 0.249 ± 0.068 µm in healthy kidneys and a significant higher mean foot process width of 0.675 ± 0.256 µm in minimal change disease patients indicating effacement of foot processes...
September 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28902011/meibomian-gland-dysfunction-associated-with-periocular-radiotherapy
#20
Young Jun Woo, JaeSang Ko, Yong Woo Ji, Tae-Im Kim, Jin Sook Yoon
PURPOSE: To investigate the influence of periocular radiotherapy on meibomian glands. METHODS: We evaluated 28 patients (40 eyes) who received radiotherapy (RT group) for conjunctival or orbital lymphoma and 30 age-matched control subjects (60 eyes). Subjects underwent slit-lamp examination of the eyelids, Schirmer test, meibography, and evaluation of tear film breakup time (TBUT), Ocular Surface Disease Index (OSDI) scores, meibomian glands evaluation (meiboscore, meibum expressibility, and lid margin abnormality scores), and tear film lipid layer thickness using an ocular surface interferometer...
September 8, 2017: Cornea
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