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https://www.readbyqxmd.com/read/27834178/the-danish-national-database-for-asthma-establishing-clinical-quality-indicators
#1
REVIEW
Susanne Hansen, Benjamin Hoffmann-Petersen, Asger Sverrild, Elvira V Bräuner, Jesper Lykkegaard, Uffe Bodtger, Lone Agertoft, Lene Korshøj, Vibeke Backer
Asthma is one of the most common chronic diseases worldwide affecting more than 300 million people. Symptoms are often non-specific and include coughing, wheezing, chest tightness, and shortness of breath. Asthma may be highly variable within the same individual over time. Although asthma results in death only in extreme cases, the disease is associated with significant morbidity, reduced quality of life, increased absenteeism, and large costs for society. Asthma can be diagnosed based on report of characteristic symptoms and/or the use of several different diagnostic tests...
2016: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27603397/modification-of-the-association-between-smoking-status-and-severity-of-coronary-stenosis-by-vitamin-d-in-patients-suspected-of-coronary-heart-disease
#2
Kuibao Li, Xiyan Yang, Lefeng Wang, Mulei Chen, Wenshu Zhao, Li Xu, Xinchun Yang
Given both smoking and vitamin D are associated with coronary heart disease (CHD) via inflammation and smoking may interfere with the local antiinflammatory effects of vitamin D. We hypothesized that the relationship between smoking and severity of CHD may be modified by vitamin D.A cross-sectional study was conducted. 25-OH vitamin D values were determined in 348 consecutive patients (mean age 62.4 ± 10.5 years; 56.3% male) undergoing coronary angiography at the Heart Center of Chaoyang Hospital affiliated to Capital Medical University between the period of September 2014 and May 2015...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27170624/national-trends-in-prescription-drug-expenditures-and-projections-for-2016
#3
Glen T Schumock, Edward C Li, Katie J Suda, Michelle D Wiest, JoAnn Stubbings, Linda M Matusiak, Robert J Hunkler, Lee C Vermeulen
PURPOSE: Historical trends and factors likely to influence future pharmaceutical expenditures are discussed, and projections are made for drug spending in 2016 in nonfederal hospitals, clinics, and overall (all sectors). METHODS: Drug expenditure data through calendar year 2015 were obtained from the IMS Health National Sales Perspectives database and analyzed. Other factors that may influence drug spending in hospitals and clinics in 2016, including new drug approvals and patent expirations, were also reviewed...
July 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27071315/corporate-and-hospital-profiteering-in-emergency-medicine-problems-of-the-past-present-and-future
#4
Robert W Derlet, Robert M McNamara, Scott H Plantz, Matthew K Organ, John R Richards
BACKGROUND: Health care delivery in the United States has evolved in many ways over the past century, including the development of the specialty of Emergency Medicine (EM). With the creation of this specialty, many positive changes have occurred within hospital emergency departments (EDs) to improve access and quality of care of the nation's de facto "safety net." The specialty of EM has been further defined and held to high standards with regard to board certification, sub-specialization, maintenance of skills, and research...
June 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/26945846/the-association-of-melioidosis-with-climatic-factors-in-darwin-australia-a-23-year-time-series-analysis
#5
Mirjam Kaestli, Eric P M Grist, Linda Ward, Audrey Hill, Mark Mayo, Bart J Currie
OBJECTIVES: Melioidosis is an often fatal disease in humans and animals and endemic in Southeast Asia and northern Australia. It is caused by the environmental bacterium Burkholderia pseudomallei. We analysed weather and climate factors preceding new melioidosis cases in Darwin and compared the time between weather event and admission to hospital for severe and average wet season rainfall. METHODS: In a time-series analysis from 1990 to 2013 we applied a boosted regression tree and a negative binomial model to investigate the association between melioidosis cases and weather events...
June 2016: Journal of Infection
https://www.readbyqxmd.com/read/26921289/responding-to-acute-care-needs-of-patients-with-cancer-recent-trends-across-continents
#6
REVIEW
Alison Young, Ernie Marshall, Monika Krzyzanowska, Bridget Robinson, Sean Brown, Fiona Collinson, Jennifer Seligmann, Afroze Abbas, Adrian Rees, Daniel Swinson, Helen Neville-Webbe, Peter Selby
Remarkable progress has been made over the past decade in cancer medicine. Personalized medicine, driven by biomarker predictive factors, novel biotherapy, novel imaging, and molecular targeted therapeutics, has improved outcomes. Cancer is becoming a chronic disease rather than a fatal disease for many patients. However, despite this progress, there is much work to do if patients are to receive continuous high-quality care in the appropriate place, at the appropriate time, and with the right specialized expert oversight...
March 2016: Oncologist
https://www.readbyqxmd.com/read/26836803/the-road-to-success-long-term-prognosis-for-persons-living-with-hiv-in-denmark-time-trends-and-risk-factors
#7
Nicolai Lohse
The work on this thesis began in 2003 when the global HIV epidemic was out of control. A minority of persons with HIV were benefitting fully from the recently introduced highly efficacious antiretroviral therapy (ART) combinations. Among the global challenges were lack of access to good healthcare, drug toxicity, and emergence of drug-resistant virus. It was unknown how long the drugs could maintain their efficacy in the individual even if administered as intended, and there was a fear that the increased drug pressure would increase the prevalence of drug resistance, subsequently leading to transmission of resistant virus from one individual to another, and thereby waning the treatment options available...
February 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/26586158/primary-breast-sarcoma-a-retrospective-study-over-35-years-from-a-single-institution
#8
Maibritt Holm, Ninna Aggerholm-Pedersen, Marco Mele, Peter Jørgensen, Steen Baerentzen, Akmal Safwat
AIM: The aim of this study was to contribute to the collected knowledge of prognostic factors in primary breast sarcomas (PBS) to the benefit of possible future prospective studies and therapeutic guidelines. METHOD: All patients with pathologically verified PBS in the period of 1979-2014 were extracted from a hospital-based database at Aarhus University Hospital. All records were reviewed for patient and tumor characteristics. Primary endpoints were overall survival, disease-free survival (DFS) and disease-specific survival (DSS)...
May 2016: Acta Oncologica
https://www.readbyqxmd.com/read/26375539/physician-hospital-alignment-in-orthopedic-surgery
#9
Brandon D Bushnell
The concept of "alignment" between physicians and hospitals is a popular buzzword in the age of health care reform. Despite their often tumultuous histories, physicians and hospitals find themselves under increasing pressures to work together toward common goals. However, effective alignment is more than just simple cooperation between parties. The process of achieving alignment does not have simple, universal steps. Alignment will differ based on individual situational factors and the type of specialty involved...
September 2015: Orthopedics
https://www.readbyqxmd.com/read/26363567/high-seroprevalence-of-hcv-in-the-abruzzo-region-italy-results-on-a-large-sample-from-opt-out-pre-surgical-screening
#10
Ennio Polilli, Monica Tontodonati, Maria Elena Flacco, Tamara Ursini, Palmira Striani, Dante Di Giammartino, Maurizio Paoloni, Luigi Vallarola, Gabriella Lucidi Pressanti, Giorgia Fragassi, Patrizia Accorsi, Lamberto Manzoli, Giustino Parruti
PURPOSE: Available estimates of the prevalence of chronic HCV infection in Italy are quite conflicting, varying from 1.5 to 22.5%, with an apparent north to south gradient. As Direct Acting Antivirals are expensive, both National and local governmental Agencies are in urgent need of detailed and reliable estimates of HCV patients to be treated, nationwide and in each district. We investigated the prevalence of anti-HCV antibodies in a large unselected sample of surgical patients providing consent to in-hospital opt-out pre-surgical HCV screening, at two hospitals from the Abruzzo Region, Italy...
February 2016: Infection
https://www.readbyqxmd.com/read/26329284/neonatal-mri-is-associated-with-future-cognition-and-academic-achievement-in-preterm-children
#11
Henrik Ullman, Megan Spencer-Smith, Deanne K Thompson, Lex W Doyle, Terrie E Inder, Peter J Anderson, Torkel Klingberg
School-age children born preterm are particularly at risk for low mathematical achievement, associated with reduced working memory and number skills. Early identification of preterm children at risk for future impairments using brain markers might assist in referral for early intervention. This study aimed to examine the use of neonatal magnetic resonance imaging measures derived from automated methods (Jacobian maps from deformation-based morphometry; fractional anisotropy maps from diffusion tensor images) to predict skills important for mathematical achievement (working memory, early mathematical skills) at 5 and 7 years in a cohort of preterm children using both univariable (general linear model) and multivariable models (support vector regression)...
November 2015: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/25959891/-barriers-and-facilitators-to-the-implementation-of-computerized-decision-support-systems-in-italian-hospitals-a-grounded-theory-study
#12
Elisa Giulia Liberati, Laura Galuppo, Mara Gorli, Marco Maraldi, Francesca Ruggiero, Matteo Capobussi, Rita Banzi, Koren Kwag, Giuseppe Scaratti, Oriana Nanni, Pietro Ruggieri, Hernan Polo Friz, Claudio Cimminiello, Marco Bosio, Massimo Mangia, Lorenzo Moja
INTRODUCTION: Computerized Decision Support Systems (CDSSs) connect health care professionals with high-quality, evidence-based information at the point-of-care to guide clinical decision-making. Current research shows the potential of CDSSs to improve the efficiency and quality of patient care. The mere provision of the technology, however, does not guarantee its uptake. This qualitative study aims to explore the barriers and facilitators to the use of CDSSs as identified by health providers...
April 2015: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/25656311/japan-as-the-front-runner-of-super-aged-societies-perspectives-from-medicine-and-medical-care-in-japan
#13
Hidenori Arai, Yasuyoshi Ouchi, Kenji Toba, Tamao Endo, Kentaro Shimokado, Kazuo Tsubota, Seiichi Matsuo, Hidezo Mori, Wako Yumura, Masayuki Yokode, Hiromi Rakugi, Shinichi Ohshima
BACKGROUND: The demographic structure of a country changes dramatically with increasing trends toward general population aging and declining birth rates. In Japan, the percentage of the elderly population (aged ≥65 years) reached 25% in 2013; it is expected to exceed 30% in 2025 and reach 39.9% in 2060. The national total population has been decreasing steadily since its peak reached in 2008, and it is expected to fall to the order of 80 million in 2060. Of the total population, those aged ≥75 years accounted for 12...
June 2015: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/25559166/effect-of-medicare-s-nonpayment-for-hospital-acquired-conditions-lessons-for-future-policy
#14
Teresa M Waters, Michael J Daniels, Gloria J Bazzoli, Eli Perencevich, Nancy Dunton, Vincent S Staggs, Catima Potter, Naleef Fareed, Minzhao Liu, Ronald I Shorr
IMPORTANCE: In 2008, Medicare implemented the Hospital-Acquired Conditions (HACs) Initiative, a policy denying incremental payment for 8 complications of hospital care, also known as never events. The regulation's effect on these events has not been well studied. OBJECTIVE: To measure the association between Medicare's nonpayment policy and 4 outcomes addressed by the HACs Initiative: central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), hospital-acquired pressure ulcers (HAPUs), and injurious inpatient falls...
March 2015: JAMA Internal Medicine
https://www.readbyqxmd.com/read/25489179/review-of-maternal-mortality-in-ethiopia-a-story-of-the-past-30-years
#15
REVIEW
Yifru Berhan, Asres Berhan
BACKGROUND: Ethiopia is one of the six countries which have contributed to more than 50% of all maternal deaths across the world. This country has adopted the millennium development goals (MDGs) including reducing the maternal mortality by three-quarter, and put improvement in maternal health as one of the health sector development program (HSDP) performance indicators. The purpose of this study was to review the maternal mortality ratio (MMR) in Ethiopia in the past 30 years using available literature...
September 2014: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/25268728/radiation-therapy-remains-the-key-cost-driver-of-oncology-inpatient-treatment
#16
Mihajlo Jakovljevic, Ana Zugic, Ana Rankovic, Aleksandar Dagovic
OBJECTIVE: Current radiation therapy capacities in Serbia and most of Eastern Europe are heavily lagging behind population needs. The primary study aim was assessment of direct costs of cancer medical care for patients suffering from cancer with assigned radiotherapy-based treatment protocols. Identification of key cost drivers and trends during 2010-2013 comparing brachytherapy and teleradiotherapy was a secondary objective of the study. METHODS: Retrospective, bottom-up database analysis was conducted on electronic discharge invoices...
January 2015: Journal of Medical Economics
https://www.readbyqxmd.com/read/25234510/long-term-use-and-cost-effectiveness-of-secondary-prevention-drugs-for-heart-disease-in-western-australian-seniors-wamach-a-study-protocol
#17
Anthony S Gunnell, Matthew W Knuiman, Elizabeth Geelhoed, Michael S T Hobbs, Judith M Katzenellenbogen, Joseph Hung, Jamie M Rankin, Lee Nedkoff, Thomas G Briffa, Michael Ortiz, Malcolm Gillies, Anne Cordingley, Mitch Messer, Christian Gardner, Derrick Lopez, Emily Atkins, Qun Mai, Frank M Sanfilippo
INTRODUCTION: Secondary prevention drugs for cardiac disease have been demonstrated by clinical trials to be effective in reducing future cardiovascular and mortality events (WAMACH is the Western Australian Medication Adherence and Costs in Heart disease study). Hence, most countries have adopted health policies and guidelines for the use of these drugs, and included them in government subsidised drug lists to encourage their use. However, suboptimal prescribing and non-adherence to these drugs remains a universal problem...
2014: BMJ Open
https://www.readbyqxmd.com/read/24924638/-scientific-evidence-for-laparoscopic-rectal-cancer-surgery
#18
REVIEW
A Fürst, A Heiligensetzer, P Sauer, G Liebig-Hörl
BACKGROUND: Innovative surgical techniques in colorectal surgery aim to provide diminished surgical injury and at least equivalent or even improved quality of treatment and oncological results. High level clinical studies are mandatory to examine the feasibility and advantages (or disadvantages) of new operative techniques. OBJECTIVES: Laparoscopic colonic resection for cancer has been investigated with respect to safety and oncological quality in various prospective randomized studies (COST study, COLOR-I and CLASICC)...
July 2014: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/24721263/cannabinoid-receptor-type-1-immunoreactivity-and-disease-severity-in-human-epithelial-ovarian-tumors
#19
Enrico Michelino Messalli, Flavio Grauso, Rossella Luise, Anna Angelini, Raffaele Rossiello
OBJECTIVE: In light of recent findings indicating that endocannabinoid system has antitumor actions, our study aimed to localize it in the human epithelial ovarian tumors, highlighting the differences among benign, borderline, and invasive forms and correlating cannabinoid receptor type 1 (CB1R) expression with disease severity. STUDY DESIGN: We determined CB1R immunohistochemical expression in 66 epithelial ovarian tumors treated in the Department of Woman, Child, and General and Specialized Surgery, Second University of Naples, at S...
September 2014: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/24589540/national-trends-in-prescription-drug-expenditures-and-projections-for-2014
#20
Glen T Schumock, Edward C Li, Katie J Suda, Linda M Matusiak, Robert J Hunkler, Lee C Vermeulen, James M Hoffman
PURPOSE: An analysis of trends in U.S. pharmaceutical spending is presented, including projections for drug expenditures in nonfederal hospital and clinic settings in 2014. METHODS: Trends in pharmaceutical expenditures and developments likely to influence future spending, including new drug approvals and patent expirations, were analyzed using data from the IMS Health National Sales Perspectives database. Projections were based on a combination of quantitative and qualitative analyses and expert opinion...
March 15, 2014: American Journal of Health-system Pharmacy: AJHP
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