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https://www.readbyqxmd.com/read/29691571/-case-based-learning-based-on-cbct-software-in-clinical-teaching-of-oral-and-maxillofacial-radiology
#1
Ling Zhu, Xia Cao, Xiao-Feng Tao
PURPOSE: To compare the teaching result of case-based learning based on cone-beam CT (CBCT) software and traditional pantomography. METHODS: Thirty-eight interns (7-year programme) of grade 2011 from College of Stomatology, Shanghai Jiao Tong University were enrolled. The inner diameter of the nasopalatine ducts (A), the length of upper canine's pulp cavity (B), the length between root furcation of upper first molar and the maxillary sinus (C), the length between the root of lower wisdom tooth and the inferior alveolar nerve (D) were measured on pantomographic films and CBCT in the same case...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29691333/community-development-between-porphyromonas-gingivalis-and-candida-albicans-mediated-by-inlj-and-als3
#2
Maryta N Sztukowska, Lindsay C Dutton, Christopher Delaney, Mark Ramsdale, Gordon Ramage, Howard F Jenkinson, Angela H Nobbs, Richard J Lamont
The pleiomorphic yeast Candida albicans is a significant pathogen in immunocompromised individuals. In the oral cavity, C. albicans is an inhabitant of polymicrobial communities, and interspecies interactions promote hyphal formation and biofilm formation. C. albicans colonizes the subgingival area, and the frequency of colonization increases in periodontal disease. In this study, we investigated the interactions between C. albicans and the periodontal pathogen Porphyromonas gingivalis C. albicans and P...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29690934/multi-dimensional-analysis-of-oral-cavity-and-oropharyngeal-defects-following-cancer-extirpation-surgery-a-cadaveric-study
#3
Sherif Idris, Alex M Mlynarek, Khalid Ansari, Jeffrey R Harris, Nabil Rizk, David Cote, Daniel A O'Connell, Heather Allen, Peter Dziegielewski, Hadi Seikaly
BACKGROUND: Defects following resection of tumors in the head and neck region are complex; more detailed and defect-specific reconstruction would likely result in better functional and cosmetic outcomes. The objectives of our study were: 1) to improve the understanding of the two- and three-dimensional nature of oral cavity and oropharyngeal defects following oncological resection and 2) to assess the geometric dimensions and the shapes of fasciocutaneous free flaps and locoregional tissue flaps required for reconstruction of these defects...
April 24, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29690702/-influencing-factors-for-keratinized-differentiation-of-keratinocytes
#4
X X Ding, X Li, J Wang, X M Gu, A Q Wu, Y M Zhou
Keratinized mucosa in oral cavity plays an important role in periodontal health. The defect of keratinized mucosa may increase the risks of complication of oral implant surgery and restoration. Graft of keratinized tissue and connective tissue are still the gold standard for treating keratinized mucosa defect now. The current research focus on how to modulate non-keratinized mucosa to highly-efficient and minimally-invasive keratinized mucosa. Keratinocytes are critical components of oral mucosa and its final differentiation into keratinized mucosa is controlled by the connective tissue microenvironment involving a variety of molecules and ions...
April 9, 2018: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29688034/non-invasive-diagnosis-of-type-2-diabetes-in-helicobacter-pylori-infected-patients-using-isotope-specific-infrared-absorption-measurements
#5
Suman Som, Gourab Dutta Banik, Abhijit Maity, Chiranjit Ghosh, Sujit Chaudhuri, Manik Pradhan
Helicobacter pylori causes several gastrointestinal diseases and may also contribute to the development of type 2 diabetes (T2D). Several studies suggest that there might be a potential link between H. pylori infection and T2D, but it still remains the subject of debate. Here, we first report the cumulative effect of H. pylori infection and T2D by exploiting the excretion kinetics of 13 C/12 C and 18 O/16 O isotope ratios of exhaled breath CO2 in response to an oral dose of 13 C-enriched glucose in individuals with T2D and non-diabetic controls (NDC) harbouring the H...
April 24, 2018: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/29687452/gingival-crevicular-fluid-levels-of-human-beta-defensin-1-in-individuals-with-and-without-chronic-periodontitis
#6
L C M Costa, K R Soldati, D C Fonseca, J E Costa, M H N G Abreu, F O Costa, D L Zandim-Barcelos, L O M Cota
BACKGROUND AND OBJECTIVE: Human beta-defensins (hBDs) contribute to innate immunity antimicrobial activity. They are also effective in the adaptive immune response and may play a crucial role in the susceptibility to diseases of the oral cavity. This study aimed to evaluate the levels of hBD-1 in the gingival crevicular fluid of individuals with and without chronic periodontitis. MATERIAL AND METHODS: Twenty periodontally healthy individuals (H) and 20 individuals with chronic periodontitis were recruited...
April 23, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29685874/impact-of-oral-side-effects-from-conditioning-therapy-before-hematopoietic-stem-cell-transplantation-protocol-for-a-multicenter-study
#7
Michael T Brennan, Bengt Hasséus, Allan J Hovan, Judith E Raber-Durlacher, Nicole Ma Blijlevens, Marie-Charlotte Huysmans, Karin Garming Legert, Jan-Erik Johansson, Charity G Moore, Inger von Bültzingslöwen
BACKGROUND: The oral cavity is a common site of complications related to the cytotoxic effect of high-dose chemotherapy and radiation therapy. Considering our limited understanding of the burden of illness in the oral cavity from various cytotoxic therapies, it is difficult to produce evidence-based, preventive and management protocols. A prospective multicenter study is necessary to collect data on the burden of illness from various cytotoxic regimens. OBJECTIVE: The objectives of this prospective international observational multicenter study in hematopoietic stem cell transplant (HSCT) patients are to establish the nature, incidence and temporal relationship of oral complications related to conditioning regimens (chemotherapy with or without total body irradiation), stem cell transplantation and the immunologic reactions (mainly graft-vs-host-disease) that may follow, and to determine what subjective and objective oral complications related to treatment can predict negative clinical and economic outcomes and reduced quality of life...
April 23, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29685504/the-influence-of-marital-status-on-survival-for-patients-aged-65-years-and-younger-with-oral-cavity-cancer
#8
Pei-Hsun Liao, Ching-Chih Lee
OBJECTIVE: In Taiwan, the median age of diagnosis for oral cavity cancer is 51 year old, which is about 10 years earlier than that in Western countries. A recent study assessing the effect of marriage on outcomes for elderly oral cavity cancer patients (≥66 years old) showed that marriage was associated with better survival. However, little is known about the prognostic significance of marital status in oral cavity cancer patients aged 65 years and younger. METHODS: Data from 2007 to 2014 were collected from the Cancer Registry Dataset of the Kaohsiung Veterans General Hospital...
April 20, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29684056/bifidobacteria-isolated-from-vaginal-and-gut-microbiomes-are-indistinguishable-by-comparative-genomics
#9
Aline C Freitas, Janet E Hill
Bifidobacteria colonize the human gastrointestinal tract, vagina, oral cavity and breast milk. They influence human physiology and nutrition through health-promoting effects, play an important role as primary colonizers of the newborn gut, and contribute to vaginal microbiome homeostasis by producing lactic acid. Nevertheless, the mechanisms by which bifidobacteria are transmitted from mother to infant remains in discussion. Moreover, studies have suggested that Bifidobacterium spp. have specializations for gut colonization, but comparisons of strains of the same bifidobacteria species from different body sites are lacking...
2018: PloS One
https://www.readbyqxmd.com/read/29683408/palatability-and-oral-cavity-tolerability-of-thc-cbd-oromucosal-spray-and-possible-improvement-measures-in-multiple-sclerosis-patients-with-resistant-spasticity-a-pilot-study
#10
Giacomo Lus, Roberto Cantello, Maura Chiara Danni, Agusto Rini, Paola Sarchielli, Tiziana Tassinari, Elisabetta Signoriello
AIM: Complaints about Δ9 -tetrahydrocannabinol (THC):cannabidiol (CBD) oromucosal spray (Sativex® ; GW Pharma Ltd, Sailsbury, UK) in the management of multiple sclerosis spasticity include unpleasant taste and oral mucosal anomalies. This pilot study assessed the use of sugar-free chewing gum and/or a refrigerated bottle of THC:CBD oromucosal spray to mitigate these effects. MATERIALS & METHODS: Patients with multiple sclerosis spasticity (n = 52) at six sites in Italy who were receiving THC:CBD oromucosal spray and had associated oral mucosal effects were randomized into Group A (chewing gum; n = 15); Group B (cold bottle; n = 20); and Group C (cold bottle + chewing gum; n = 17)...
April 23, 2018: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/29682688/what-is-the-benefit-of-using-amniotic-membrane-in-oral-surgery-a-comprehensive-review-of-clinical-studies
#11
REVIEW
M Fénelon, S Catros, J C Fricain
OBJECTIVES: Since its first use for the reconstruction of tissue defects in the oral cavity in 1985, human amniotic membrane (hAM) has been widely studied in the field of oral surgery. Despite the growing number of publications in this field, there is no systematic review or meta-analysis concerning its clinical applications, outcome assessments, and relevance in oral surgery. The aim of this review is to provide a thorough understanding of the potential use of hAM for soft and hard tissue reconstruction in the oral cavity...
April 22, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29682090/the-neuropeptide-genes-sst-tac1-hcrt-npy-and-gal-are-powerful-epigenetic-biomarkers-in-head-and-neck-cancer-a-site-specific-analysis
#12
Kiyoshi Misawa, Masato Mima, Atsushi Imai, Daiki Mochizuki, Yuki Misawa, Shiori Endo, Ryuji Ishikawa, Takeharu Kanazawa, Hiroyuki Mineta
Background: Staging and pathological grading systems are convenient but imperfect predictors of recurrence in head and neck squamous cell carcinoma (HNSCC). Identifying biomarkers for HNSCC that will progress and cause death is a critical research area, particularly if the biomarker can be linked to selection of patients. Therefore, to identify potential alternative prognostic markers, we investigated the methylation status of five neuropeptide gene promoters. The promoter methylation status was determined by quantitative methylation-specific PCR in 230 cases of HNSCC; 58 hypopharynx, 45 larynx, 56 oropharynx, and 71 oral cavity tumor samples were studied...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29681480/outcome-of-endodontic-surgery-a-meta-analysis-of-the-literature-part-3-comparison-of-endodontic-microsurgical-techniques-with-2-different-root-end-filling-materials
#13
REVIEW
Meetu R Kohli, Homayon Berenji, Frank C Setzer, Su-Min Lee, Bekir Karabucak
INTRODUCTION: The aim of the present study was to investigate the influence of root-end preparation and filling material on endodontic surgery outcome. A systematic review and meta-analysis was conducted to determine the outcome of resin-based endodontic surgery (RES, the use of high-magnification preparation of a shallow and concave root-end cavity and bonded resin-based root-end filling material) versus endodontic microsurgery (EMS, the use of high-magnification ultrasonic root-end preparation and root-end filling with SuperEBA [Keystone Industries, Gibbstown, NJ], IRM [Dentsply Sirona, York, PA], mineral trioxide aggregate [MTA], or other calcium silicate cements)...
April 19, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29679682/bitter-and-sweet-tasting-molecules-it-s-complicated
#14
REVIEW
Antonella Di Pizio, Yaron Ben Shoshan-Galeczki, John E Hayes, Masha Y Niv
"Bitter" and "sweet" are frequently framed in opposition, both functionally and metaphorically, in regard to affective responses, emotion, and nutrition. This oppositional relationship is complicated by the fact that some molecules are simultaneously bitter and sweet. In some cases, a small chemical modification, or a chirality switch, flips the taste from sweet to bitter. Molecules humans describe as bitter are recognized by a 25 member subfamily of class A G-protein coupled receptors (GPCRs) known as TAS2Rs...
April 18, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29678677/photodynamic-inactivation-of-candida-ssp-on-denture-stomatitis-a-clinical-trial-involving-palatal-mucosa-and-prosthesis-disinfection
#15
André M de Senna, Martha M F Vieira, Rosa Maria Machado-de-Sena, Aparecido O Bertolin, Silvia C Núñez, Martha S Ribeiro
Denture stomatitis (DS) is the most common oral fungal infection in denture wearers. Photodynamic inactivation (PDI) has been showing to be an effective technique in vivo against fungi, including fungal infections in the oral cavity. The disinfection of both oral mucosa and denture may represent a real advantage in terms of fungus control. This clinical study was designed to explore methylene blue (MB)-mediated PDI on oral mucosa and prosthesis of patients with DS. Subjects with DS were divided into two groups...
April 17, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29678378/desquamative-gingivitis-clinical-findings-and-diseases
#16
REVIEW
Andrea D Maderal, Paul Lee Salisbury, Joseph L Jorizzo
Desquamative gingivitis is a clinical finding with several potential etiologies. Among the most common are oral lichen planus, cicatricial pemphigoid, and pemphigus vulgaris, though various other differential diagnoses exist. The presence of desquamative gingivitis often results in poor oral hygiene, which can have downstream consequences, including periodontitis and tooth loss. Though certain mucosal findings may be suggestive of a particular diagnosis, a thorough history, physical examination, and appropriate dermato- and immunopathologic assessment is necessary for narrowing this broad differential diagnosis...
May 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29676358/frequency-distribution-and-immunomorphologic-characteristics-of-peripheral-t-cell-lymphoma-not-otherwise-specified-in-a-tertiary-care-center-in-southern-india
#17
Archana Lakshmanan, Deeksha Sikri, Sushama Patil, Ann Kurian, S Annapurneswari, Sheila Nair
Aims: In world literature, Peripheral T-cell lymphomas (PTCLs) constituted about 12% of non-Hodgkin's lymphomas (NHL) of which PTCL not otherwise specified (NOS) was the most common subtype. This study was undertaken to ascertain the frequency and to assess the morphologic and immunophenotypic characteristics of PTCL, NOS over a period of 5 years in a tertiary care referral center in Southern India. Materials and Methods: Slides and blocks of all PTCL, NOS were retrieved, and a detailed morphologic and immunophenotypic study using a wide panel of antibodies was done...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29675996/streptococcus-endopeptidases-promote-hpv-infection-in-vitro
#18
Sylvia I Pavlova, Reid V Wilkening, Michael J Federle, Yu Lu, Joel Schwartz, Lin Tao
Both cervical and throat cancers are associated with human papillomavirus (HPV). HPV infection requires cleavage of the minor capsid protein L2 by furin. While furin is present in the vaginal epithelium, it is absent in oral epithelial basal cells where HPV infection occurs. The objective of this study was to investigate whether common oral bacteria express furin-like peptidases. By screening strains representing 12 oral Streptococcus and Enterococcus species, we identified that eight Streptococcus strains displayed high levels of furin-like peptidase activity, with S...
April 19, 2018: MicrobiologyOpen
https://www.readbyqxmd.com/read/29675970/does-hypoxia-inducible-factor-1-%C3%AE-hif-1-%C3%AE-c1772t-polymorphism-predict-short-term-prognosis-in-patients-with-oral-squamous-cell-carcinoma-oscc
#19
Jitender Prasad, Binita Goswami, Srinivas H Gowda, Nikhil Gupta, Shilpa Kumar, Kiran Agarwal, Pravesh Mehra, Bindiya K Pahuja, Anju Chauhan
BACKGROUND: Oral squamous cell carcinoma (OSCC) is a cancer of the oral cavity that is a major health problem in India. There is an urgent need to identify biomarkers that have prognostic significance. We studied HIF1 α levels as well as single nucleotide polymorphism of HIF1α gene in cancer and healthy controls. METHODS: Fifty newly diagnosed OSCC patients and 50 age and sex matched healthy control were included in the study. Serum concentrations of HIF1 α were measured by sandwich ELISA; whereas HIF1 α gene polymorphism study was done using restriction enzyme digestion by HpH I...
April 20, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29675646/validation-of-the-8th-edition-of-the-ajcc-uicc-tnm-staging-system-for-tongue-squamous-cell-carcinoma
#20
Satoshi Kano, Tomohiro Sakashita, Nayuta Tsushima, Takatsugu Mizumachi, Akira Nakazono, Takayoshi Suzuki, Shinichiro Yasukawa, Akihiro Homma
BACKGROUND: The revised 8th edition of the AJCC/UICC staging system was released in January 2017, and depth of invasion (DOI) was added to the new criteria for T classification in oral cavity cancer. In this study, we evaluated whether the 8th edition presents the prognosis and risk of nodal metastasis in patients with squamous cell carcinoma of tongue more accurately than did the 7th edition. METHODS: The data for 112 patients were obtained and reclassified based on the criteria presented in the 8th edition...
April 19, 2018: International Journal of Clinical Oncology
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