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https://www.readbyqxmd.com/read/29453485/oral-squamous-papilloma-of-edentulous-mouth-interfering-with-denture-retention
#1
Nashib Pandey, Shivalal Sharma, Ashish Shrestha, Vinay Marla
Soft tissue overgrowths inside oral cavity can present with wide range of clinical manifestations and some of them can asymptomatic. Oral squamous papilloma is one of that asymptomatic lesion described in the literature with extremely low virulence and infectivity rate. Soft tissue overgrowths can sometimes interfere with denture retention. Here we report a case of squamous papilloma in a 60 years old edentulous female who presented with loss of denture retention.
October 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/29452770/single-arm-phase-2-trial-of-elective-nodal-dose-reduction-for-patients-with-locoregionally-advanced-squamous-cell-carcinoma-of-the-head-and-neck
#2
Patrick D Maguire, Charles R Neal, Stuart M Hardy, Andrew M Schreiber
PURPOSE: To evaluate a novel chemoradiation therapy (CRT) regimen for patients with squamous cell carcinoma of the head and neck (SCCHN) incorporating a lower intensity modulated radiation therapy dose to electively treated neck lymph nodes than is currently standard. METHODS AND MATERIALS: Eligible patients had locally advanced SCCHN of the oral cavity, oropharynx, larynx, or hypopharynx. The 7-week CRT course consisted of weekly cisplatin at 35 mg/m 2 concurrently with sequential-boost intensity modulated radiation therapy: 36 Gy to high- and low-risk planning target volumes followed by a sequential boost to the high-risk planning target volume to 70 Gy...
December 28, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29451926/coronally-advanced-flap-with-or-without-subepithelial-connective-tissue-graft-for-the-treatment-of-single-recession-5-year-outcomes-from-a-comparative-study
#3
Luca Francetti, Roberto Weinstein, Silvio Taschieri, Stefano Corbella
Gingival recession can cause an esthetic impairment or dentin hypersensitivity due to root surface exposure to the oral cavity. These conditions may require specific surgical interventions to achieve root coverage. This controlled clinical trial on 20 subjects compared coronally advanced flap (CAF) technique and CAF plus subepithelial connective tissue graft (CTG) for the treatment of single maxillary gingival recession. Recession height (REC) and complete root coverage (CRC) were considered as primary outcomes...
February 16, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29451605/evaluation-of-the-frequency-of-candida-spp-in-hospitalized-and-non-hospitalized-subjects
#4
J N Vieira, A M Feijó, M E Bueno, C L Gonçalves, R G Lund, J F Mendes, J P V Villarreal, M M Villela, P S Nascente
The aim of this study was to evaluate the frequency of Candida species between a non-hospitalized and a hospitalized population. For this purpose, samples of saliva were sampled through sterile swabs, moistened in peptone water and rubbed in the oral cavity of 140 individuals, from which, 70 were hospitalized patients from the Medical Clinic of a Teaching Hospital and the other 70 were non-hospitalized subjects. All saliva samples were plated in Sabouraud Dextrose agar added with Chloramphenicol and incubated at 36 °C for 48 hours...
February 15, 2018: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29451053/the-fate-of-silver-nanoparticles-in-authentic-human-saliva
#5
Kamonwad Ngamchuea, Christopher Batchelor-McAuley, Richard G Compton
The physicochemical properties of silver nanoparticles (AgNPs) in human whole saliva are investigated herein. In authentic saliva samples, AgNPs exhibit a great stability with over 70% of the nanomaterial remaining intact after a 24-h incubation in the presence of ∼0.3 mM dissolved oxygen. The small loss of AgNPs from the saliva sample has been demonstrated to be a result of two processes: agglomeration/aggregation (not involving oxygen) and oxidative dissolution of AgNPs (assisted by oxygen). In authentic saliva, AgNPs are also shown to be more inert both chemically (silver oxidative dissolution) and electrochemically (electron transfer at an electrode) than in synthetic saliva or aqueous electrolytes...
February 16, 2018: Nanotoxicology
https://www.readbyqxmd.com/read/29447997/multisensory-flavor-perception-the-relationship-between-congruency-pleasantness-and-odor-referral-to-the-mouth
#6
Robin Fondberg, Johan N Lundström, Maria Blöchl, Mats J Olsson, Janina Seubert
Our hedonic response to a food is determined by its flavor, an inherently multisensory experience that extends beyond the mere addition of its odor and taste. While congruency is known to be important for multisensory processes in general, little is known about its specific role in flavor processing. The aim of the present study was to delineate the effects of odor-taste congruency on two central aspects of flavor: odor referral (or mislocalization) to the mouth, and pleasantness. We further aimed to test whether an eventual effect on pleasantness was mediated by odor referral...
February 12, 2018: Appetite
https://www.readbyqxmd.com/read/29447885/pediatric-head-and-neck-squamous-cell-carcinoma-patient-demographics-treatment-trends-and-outcomes
#7
Ankit Modh, Omar H Gayar, Mohamed A Elshaikh, Arnold C Paulino, Farzan Siddiqui
OBJECTIVES: To examine patient demographics, temporal and treatment trends, and survival outcomes of pediatric non-nasopharyngeal head and neck squamous cell carcinomas using the National Cancer Database. METHODS: The National Cancer Database was queried for pediatric patients (age 0-19 years) diagnosed with squamous cell carcinoma of the head and neck (including oral cavity, oropharynx, nasal cavity, larynx, hypopharynx, and salivary glands) from 2004 to 2013. RESULTS: Of 159 patients identified, the majority had oral cavity SCC (55%)...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447591/characterization-of-a-partial-body-irradiation-model-with-oral-cavity-shielding-in-non-human-primates
#8
Michael V Accardi, Oreola Donini, Adam Rumage, Alexis Ascah, Julius Haruna, Mylène Pouliot, Kim Bujold, Hai Haung, Wieslaw Wierzbicki, John Stamatopoulos, Houman Naraghi, Thomas Measey, Simon Authier
PURPOSE: Characterization of a novel partial body irradiation (PBI) shielding strategy in nonhuman primates (NHP; rhesus macaques), aimed at protecting the oral cavity, with respect to various gastrointestinal (GI-ARS) syndrome parameters as well as buccal ulceration development. MATERIALS AND METHODS: NHPs were irradiated using a Cobalt-60 gamma source, in a single uniform dose, ranging from 9-13 Gy and delivered at 0.60-0.80 Gy min -1 . Animals were either partially shielded via oral cavity shielding (PBI OS ) or underwent total body irradiation (TBI)...
February 15, 2018: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/29447361/laryngeal-squamous-cell-papilloma-is-highly-associated-with-human-papillomavirus
#9
Yorihisa Orita, Yuka Gion, Tomoyasu Tachibana, Kana Ikegami, Hidenori Marunaka, Seiichiro Makihara, Yasuhiko Yamashita, Kentaro Miki, Takuma Makino, Naoki Akisada, Yusuke Akagi, Miyuki Kimura, Tadashi Yoshino, Kazunori Nishizaki, Yasuharu Sato
Objective: To delineate the association between characteristics of adult-onset laryngeal squamous cell papilloma and human papillomavirus (HPV) infection. Methods: Clinical records and paraffin-embedded specimens of 77 papilloma patients who had been treated between 1998 and 2014 were collected. Of the 77 cases, 34 were identified in the larynx, 28 in the oral cavity and 15 in the oropharynx. Specimens were investigated by polymerase chain reaction (PCR) to detect HPV 6, 11, 16, 18, 31, 33, 35, 52b and 58, and immunohistochemical (IHC) staining for anti-p16INK4a antibody...
February 13, 2018: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29445878/feasibility-of-intraoperative-detection-of-sentinel-lymph-nodes-with-89-zirconium-labelled-nanocolloidal-albumin-pet-ct-and-a-handheld-high-energy-gamma-probe
#10
Derrek A Heuveling, K Hakki Karagozoglu, Arthur Van Lingen, Otto S Hoekstra, Guus A M S Van Dongen, Remco De Bree
BACKGROUND: PET/CT lymphoscintigraphy using 89 Zr-nanocolloidal albumin has the potential to improve the preoperative identification of sentinel lymph nodes (SLNs), especially if located in the near proximity of the primary tumour. This study aims to demonstrate the feasibility of PET/CT lymphoscintigraphy followed by intraoperative detection of 89 Zr-nanocolloidal albumin containing SLNs with the use of a handheld high-energy gamma probe. METHODS: PET/CT lymphoscintigraphy was performed after peritumoural injection of 89 Zr-nanocolloidal albumin in five patients with oral cavity carcinoma planned for surgical resection...
February 14, 2018: EJNMMI Research
https://www.readbyqxmd.com/read/29445368/beneficial-oral-biofilms-as-smart-bioactive-interfaces
#11
Beatrice Gutt, Qun Ren, Irmgard Hauser-Gerspach, Piotr Kardas, Stefan Stübinger, Monika Astasov-Frauenhoffer, Tuomas Waltimo
Periodontitis is a very common health problem caused by formation of pathogenic bacterial biofilm that triggers inflammation resulting in either reversible gingivitis or irreversible periodontal hard and soft tissue damages, leading to loss of teeth when left untreated. Commensal bacteria play an important role in oral health in many aspects. Mainly by colonizing oral tissues, they (i) contribute to maturation of immune response, and (ii) foreclose attachment of pathobiont and, therefore, prevent from infection...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29445174/a-spatial-gradient-of-bacterial-diversity-in-the-human-oral-cavity-shaped-by-salivary-flow
#12
Diana M Proctor, Julia A Fukuyama, Peter M Loomer, Gary C Armitage, Stacey A Lee, Nicole M Davis, Mark I Ryder, Susan P Holmes, David A Relman
Spatial and temporal patterns in microbial communities provide insights into the forces that shape them, their functions and roles in health and disease. Here, we used spatial and ecological statistics to analyze the role that saliva plays in structuring bacterial communities of the human mouth using >9000 dental and mucosal samples. We show that regardless of tissue type (teeth, alveolar mucosa, keratinized gingiva, or buccal mucosa), surface-associated bacterial communities vary along an ecological gradient from the front to the back of the mouth, and that on exposed tooth surfaces, the gradient is pronounced on lingual compared to buccal surfaces...
February 14, 2018: Nature Communications
https://www.readbyqxmd.com/read/29443777/oral-leukoplakia-a-precancerous-lesion-of-squamous-cell-carcinoma-in-patients-with-long-term-pegylated-liposomal-doxorubicin-treatment
#13
Hidetaka Nomura, Kimihiko Sakamoto, Takeru Sugihara, Shuhei Okamoto, Yoichi Aoki, Terumi Tanigawa, Maki Matoda, Kohei Omatsu, Hiroyuki Kanao, Kazuyoshi Kato, Kuniko Utsugi, Yuko Sugiyama, Nobuhiro Takeshima
Pegylated liposomal doxorubicin (PLD) has a good safety profile, but long-term use has been associated with development of squamous cell carcinoma of the tongue and oral cavity (SCCTO) in some patients. The study objective was to estimate the prevalence of oral leukoplakia, a known precursor of SCCTO, in patients with ovarian cancer and long-term PLD use.After approval of the institutional review board, medical record of 114 patients who were treated with PLD at our institution between January 2010 and December 2016 were retrospectively reviewed...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29442455/oral-mucositis-and-saliva-iga-igg-and-igm-concentration-during-anti-tumor-treatment-in-children-suffering-from-acute-lymphoblastic-leukemia
#14
Elżbieta J Pels
BACKGROUND: Oral mucositis is a problem occurring within the oral cavity, which is the most difficult to deal with during anti-tumor treatment. The first symptom reported by the patient is discomfort. Salivary immunoglobulins play an important role in pathological processes occurring in the oral cavity. OBJECTIVES: The study objective was to assess the occurrence of oral mucositis and to assess changes in the saliva IgA, IgG, and IgM concentration in children with acute lymphoblastic leukemia during antitumor treatment...
December 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29442089/reactive-hyperplastic-lesions-of-the-oral-cavity-a-retrospective-survey-study-and-literature-review
#15
Varsha Ajit Sangle, V K Pooja, Anuja Holani, Nishat Shah, Mayur Chaudhary, Sneha Khanapure
Context: The reactive lesions are relatively common in the oral cavity because of the frequency with which the tissues are injured. They often result from a known stimulus or injury such as dental plaque, calculus, or foreign material. Aims: The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at MIDSR, Dental College and Hospital, Latur, Maharashtra, and to compare these data with those of previously reported studies...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29442085/an-insight-into-diagnosis-of-a-hidden-entity-impacted-food-material
#16
Humeera M Mulla, Nupura Vibhute, Rajendra Baad, N D Shashikiran, Mustaq Parker, R C Parmod, Uzma Belgaumi, Vidya Kadashetti, Sushma Bommanawar
Introduction: Foreign bodies and tissue reactions to foreign materials are commonly encountered in the oral cavity. Exogenous materials causing foreign body reactions may be metallic (amalgam) or nonmetallic (suture materials, vegetable matter). Implantation of food particles in the oral tissues has been known to cause reactive lesions such as oral pulse granuloma. Implantation could be through extraction sockets, deep periodontal pockets, associated with tumor growth, interdental areas of teeth, unfilled root canals, and grossly decayed teeth...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29442081/qualitative-and-quantitative-salivary-changes-and-subjective-oral-dryness-among-patients-with-thyroid-dysfunction
#17
Meghal Mehul Naik, Vaishnavee Vassandacoumara
Context: There is a paucity of literature regarding the effects of thyroid disorders on the oral cavity by influencing the salivary gland function. Aims: This study aims to understand the qualitative and quantitative changes that thyroid disorder can cause in the salivary function. Settings and Design: After obtaining ethical clearance, 46 consecutive newly diagnosed thyroid dysfunction patients were enrolled in this cross-sectional study, along with 45 age-and sex-matched controls...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29440948/orofacial-manifestations-of-adverse-drug-reactions-a-review-study
#18
REVIEW
Sedigheh Bakhtiari, Marziye Sehatpour, Hamed Mortazavi, Mahin Bakhshi
Background: Adverse reaction to medication is common and may have a variety of clinical manifestations in the oral cavity. The present review paper aimed to describe adverse drug reactions (ADRs) which might be encountered by dental practitioners in every discipline. Methods: In this narrative review article, the specialized databases such as PubMed, PubMed Central, MEDLINE, EBSCO, Science Direct, Scopus, and reference books from the years 2000-2016 were used to find relevant documents by using MeSH terms: Adverse Drug Reaction, Drug induced, Medication Related, Mouth, Oral Manifestation, Tooth, Hard Tissue, Soft Tissue...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29440924/alterations-in-oral-microbial-flora-induced-by-waterpipe-tobacco-smoking
#19
Muhamad Ali K Shakhatreh, Omar F Khabour, Karem H Alzoubi, Majed M Masadeh, Emad I Hussein, George N Bshara
Background: Waterpipe smoking is a global health problem and a serious public concern. Little is known about the effects of waterpipe smoking on oral health. In the current study, we examined the alterations of oral microbial flora by waterpipe smoking. Methods: One hundred adult healthy subjects (59 waterpipe smokers and 41 non-smokers) were recruited into the study. Swabs were taken from the oral cavity and subgingival regions. Standard culturing techniques were used to identify types, frequency, and mean number of microorganisms in cultures obtained from the subjects...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29440792/ancient-schwannoma-of-gingiva-a-rare-case-report
#20
Manas Bajpai, Nilesh Pardhe
Oral schwannomas (OSs) are rare benign tumors of oral cavity derived from peripheral nerve sheath, composed of proliferation of schwann cells in a characteristic pattern. AS are long-standing lesions which exhibit degenerative changes and atypia due to which they could be mistaken for malignancy. The mean age of occurrence of AS in oral cavity is 43 years, and no case of oral AS has been reported in a pediatric patient so far. Here, we present a rare case of AS of oral cavity in a 10-year-old male child.
May 2017: Journal of Indian Society of Periodontology
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