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Bernard Ars, Joris Dirckx
The fibrocartilaginous eustachian tube is part of a system of contiguous organs including the nose, palate, rhinopharynx, and middle ear cleft. The middle ear cleft consists of the tympanic cavity, which includes the bony eustachian tube (protympanum) and the mastoid gas cells system. The tympanic cavity and mastoid gas cells are interconnected and allow gaseous exchange and pressure regulation. The fibrocartilaginous eustachian tube is a complex organ consisting of a dynamic conduit with its mucosa, cartilage, surrounding soft tissue, peritubal muscles (ie, tensor and levator veli palatine, salpingopharyngeus and tensor tympani), and superior bony support (the sphenoid sulcus)...
October 2016: Otolaryngologic Clinics of North America
Nicola Boari, Filippo Gagliardi, Andrea Cavalli, Marco Gemma, Luca Ferrari, Paola Riva, Pietro Mortini
OBJECTIVE Skull base chordomas (SBCs) are rare dysembryogenetic invasive tumors with a variable tendency for recurrence. According to previous studies, the recurrence rate seems to be affected by both clinical variables and tumor biological features. The authors present the results of treatment of SBCs in a large series of patients and investigate the role of 1p36 chromosomal region loss of heterozygosity (LOH) as a prognostic factor. METHODS Between 1990 and 2011, 45 patients were treated for SBCs. The mean follow-up was 76 months (range 1-240 months)...
August 2016: Journal of Neurosurgery
M Santagati, M Scillato, N Muscaridola, V Metoldo, I La Mantia, S Stefani
Streptococcus salivarius, a non-pathogenic species and the predominant colonizer of the oral microbiota, finds a wide application in the prevention of upper respiratory tract infections, also reducing the frequency of their main pathogens. In this pilot study, the primary objective was to evaluate the safety and tolerability of a nasal spray, S. salivarius 24SMBc, as a medical device in a clinical study involving 20 healthy adult subjects. The secondary aim was to determine the ability of colonization assessed by molecular fingerprinting...
October 2015: European Journal of Clinical Microbiology & Infectious Diseases
Louise Buchreitz Herlow, Birgitte Charabi
Polymorphous low-grade adenocarcinoma is a rare tumour of the rhinopharynx. This is a case report of a 32-year-old Danish man who was treated by primary surgical excision in Hong Kong via the maxillary swing approach and post-operative irradiation therapy in Denmark. Since September 2012 this surgical modality has been offered at Rigshospitalet in Copenhagen.
February 23, 2015: Ugeskrift for Laeger
Rosamaria Fastuca, Piero Antonio Zecca, Alberto Caprioglio
BACKGROUND: Oral breathing and maxillary deficiency are often associated with steep mandibular plane angle, and retrognathic mandible compared with the faces of healthy controls. Some studies suggested that after rapid maxillary expansion, improvement in nasal breathing and repositioning of mandible with transitory increasing of facial height and, in some cases, spontaneous forward repositioning might occur. The above-mentioned mandibular effects could contribute to enlarge oropharynx volume with repositioning of tongue and soft palate with an improvement of upper airway volume after treatment...
2014: Progress in Orthodontics
Luca Raimondo, Massimiliano Garzaro, Luca Molinaro, Claudia Bartoli, Erica Provenzano, Giancarlo Pecorari
Localized nasal argyria has been reported in 3 published articles as secondary to occupational exposure and involving the anterior part of the nose. No previous cases of such pathology involving the rhinopharynx were described. Here we report the first case of localized argyria of the roof and of the posterior wall of the rhinopharynx secondary to prolonged use of nasal drops containing colloidal silver protein. The recognition of such pathology can be useful to increase the number of conditions that must be considered in the differential diagnosis of rhinopharyngeal mucosa alterations...
2014: Journal of Craniofacial Surgery
Felicia Andrei, Andrei Gheorghe Marius Motoc, Adelina Maria Jianu, Mugurel Constantin Rusu, Carla Loreto
INTRODUCTION: The rhinopharynx and the parapharyngeal space (PPS) are complex anatomical territories located beneath the skull base. Thorough knowledge of the complex anatomy of the PPS is essential in treatment of pathologies such as parapharyngeal abscesses. The roof of the PPS is overlooked in anatomy. It was hypothesized that the pneumatization pattern of the PPS roof is individually variable, as determined by the variable pneumatization patterns of the sphenoid and temporal bones...
December 1, 2012: Germs
O Gallo, R Santoro, F R Fiorini, G Meccariello, R M Laganà, F Paiar, V Maio
BACKGROUND AND OBJECTIVES: Sparing internal jugular vein (IJV) in neck dissection for head and neck cancer is controversial. We aimed at evaluating the prognostic impact of IJV preservation. METHODS: We examined 206 files of head and neck cancer patients who underwent radical or modified radical neck dissection at the Otolaryngology University of Florence. The site of primary tumor was larynx and hypopharynx in 44.66%, oropharynx in 25.24%, oral cavity in 23.3%, unknown in 4...
December 2013: Journal of Surgical Oncology
I S Petersen, P L Larsen, B L Brandelev, J Hald, C Prætorius, R Welinder, B Bruun
This study provides data on prevalence of Staphylococcus aureus in oropharynx, rhinopharynx and vestibulum nasi. Specimens were taken from these three pharyngeal sites in 346 patients and analysed for S. aureus. Abnormal pharyngeal findings and patient histories were recorded. S. aureus was found in 8.1%, 7.2% and 20.2% of all specimens from oropharynx, rhinopharynx and vestibulum nasi, respectively. A strong association between colonization of oropharynx and rhinopharynx was found, especially when vestibulum nasi was not colonized...
July 2013: Journal of Hospital Infection
Rosa Morabito, Marcello Longo, Andrea Rossi, Paolo Nozza, Francesca Granata
We report the CT and MR characteristics of a newborn with a rare, complex malformation characterised by a large rhinopharyngeal and oropharyngeal enterogenous cyst, associated with an osseous defect of the basiocciput, called canalis basilaris medianus (CBM). A partial herniation of the bulb was demonstrated through the bony defect on the midline. The enterogenous cyst occupied the rhinopharynx and oropharynx, narrowing the pharyngeal lumen and making it difficult for the introduction of an orotracheal tube...
April 2013: Pediatric Radiology
Fabio Pagella, Francesco Chu, Alessandro Pusateri, Elina Matti
Pleomorphic adenoma is the most common benign tumor of the parotid glands. Rarely it may arise from minor salivary glands of the upper aerodigestive tract. A 57-year-old woman was admitted at our institution presenting with nasal obstruction. Endoscopic evaluation revealed a pedicled mass in the rhinopharynx. After radiological examination, we opted for a transnasal endoscopic-assisted excision of the mass under general anaesthesia. Histological evaluation deponed for pleomorphic adenoma with clear surgical margins...
2012: Case Reports in Medicine
Ramona Denise Mălin, Elena Ioniţă, I Osman, Carmen Aurelia Mogoantă, Luminiţa Cioroianu, S Ciolofan, F Anghelina, Mădălina Enăchescu
In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC and EBV. In the cases studied tumors accompanied by seemingly primitive adenopathies were located in the thyroid, lung, esophagus, stomach, rhinopharynx, hypopharynx, oropharynx and larynx.
2012: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
H Nouri, T Ziad, Y Rochdi, L Aderdour, A Raji
INTRODUCTION: Hemangioma are rare benign vascular tumors. Histologically, there are several types including capillary, cavernous and mixed hemangioma. We present a very rare mixed hemangioma of the nasal septum. CASE REPORT: A 30-year-old woman consulted for unilateral epistaxis and nasal obstruction. CT scan revealed a tumor filling the rhinopharynx, strongly enhanced after injection of contrast medium. It was pedicled on the posterior and superior nasal septum...
June 2012: Revue de Stomatologie et de Chirurgie Maxillo-faciale
Marlène Guillet, Jean-Ralph Zahar, Marc-Olivier Timsit, Laure Grandin, Etienne Carbonnelle, Olivier Join-Lambert, Gilles Quesne, Xavier Nassif, Arnaud Mejean, Anne Carbonne
Streptococcus pneumoniae is rarely isolated from nosocomial infections. We report an outbreak of 4 nosocomial-acquired surgical site infections due to S pneumoniae after retropubic simple prostatectomy. The likely source was detected in the rhinopharynx of the surgeon. After the implementation of recommendations, no new cases have been recorded.
February 2012: American Journal of Infection Control
R C Read, L Goodwin
This chapter will describe the use of organ cultures of human nasopharyngeal mucosa to study the interaction of Neisseria meningitidis with this complex tissue. Colonization of nasopharyngeal mucosa is the first step in the pathogenesis of meningococcal disease. Supporting evidence for this is the correlation between the prevalence of community carriage and the occurrence of meningococcal disease (1). During nonepidemic periods, the baseline prevalence of nasopharyngeal carriage of meningococci is 5-10% but is considerably higher in certain populations such as military personnel (2), and in households of cases (3)...
2001: Methods in Molecular Medicine
G Leo, C Incorvaia, S Masieri, F Triulzi
Symptoms of chronic rhinosinusitis (CRS) are nasal blockage, nasal discharge, postnasal drip, facial pain, headache, and reduction or loss of smell, but they are often subtle and make it difficult to obtain a firm diagnosis based only on clinical data, and especially to distinguish CRS from persistent rhinitis. A diagnosis of certainty of CRS relies upon either direct observation by nasal fibroendoscopy of nasal turbinates, middle meatus, and rhinopharynx, detecting mucopurulent discharge from the middle meatus, and/or oedema or mucosal obstruction, or by imaging of the rhinosinusal cavities...
December 2010: European Annals of Allergy and Clinical Immunology
Yash Pandya, Enrico Piccirillo, Fernando Mancini, Mario Sanna
OBJECTIVES: In a retrospective analysis of a quaternary referral neuro-otologic private practice, we identify complex cases of petrous bone cholesteatoma (i.e., cases with encasement of vital structures such as the internal carotid artery, jugular bulb, and sigmoid sinus, with further extension to the clivus, sphenoid sinus, or rhinopharynx), review surgical approaches and techniques of management of vital structures, and propose the ideal surgical management. METHODS: We performed a retrospective case study of 130 cases of petrous bone cholesteatoma submitted to surgery between 1979 and 2009 to identify the complex cases and their classification, approach used, outcomes, and recurrences...
August 2010: Annals of Otology, Rhinology, and Laryngology
A Varricchio, F Avvisati, A M Varricchio, G Tortoriello, G Ciprandi
The airways should be considered as a functional unit. Indeed, disorders involving the upper respiratory tract (URT) spread to the lower respiratory tract (LRT). Modern functional anatomy divides URT in three, mutually dependent, junction boxes: i) the ostio-meatal complex (OMC), ii) the spheno-ethmoidal recess (SER), and iii) the rhinopharynx (RP). The first is the most interesting as it joins the anterior paranasal sinuses with the nose. The correct ventilation and the effective mucociliary clearance of these three pathophysiologic junction boxes condition the healthy physiology of the entire respiratory system...
January 2010: International Journal of Immunopathology and Pharmacology
O Wauters, B Dezfoulian, V Failla, M de la Brassinne, A F Nikkels
Allergic manifestations due to outdoor plants are relatively well known, contrary to those related to home plants. This review presents the various allergens linked to home plants that may be responsible for several allergic manifestations affecting the skin, the lungs, the eyes, and the rhinopharynx. The ficus and its family members constitute the principal sources of the incriminated allergens.
November 2009: Revue Médicale de Liège
Carmen García Navalón, Miguel Armengot Carceller, Vicente Sabater Marco, Rosa M A Reboll Ferrer, Soledad Frías Moya-Angeler, Jorge Basterra Alegría, Jair Gutiérrez
Several histopathological modalities of tumours can grow in the rhinopharynx. Solitary extramedullary plasmocytoma (SEP) is a low frequent variety of low-grade lymphoma. The aim of this work is to present a new case of SEP localized in rhinopharynx and to perform a review of diagnostic and therapeutic protocols of these neoplasias. They must be taken into account in the differential diagnosis of nasopharyngeal tumours.
July 2009: Acta Otorrinolaringológica Española
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