keyword
https://read.qxmd.com/read/38534284/does-miniscrew-assisted-rapid-palatal-expansion-influence-upper-airway-in-adult-patients-a-scoping-review
#1
REVIEW
Mariachiara Benetti, Luca Montresor, Daniele Cantarella, Nicoletta Zerman, Enrico Spinas
(1) Objective: This scoping review evaluates the effects of miniscrew-assisted rapid palatal expansion (MARPE) on different regions of the upper airway in adult patients and investigates various methods of measurement. (2) Methods: The search encompassed Pubmed, Cochrane Library, Scopus and Web of Science. This review was conducted following the PRISMA_ScR guidelines, and the inclusion criteria for examined studies were chosen in accordance with the PICOS framework. (3) Results: Seven studies were included in this review, comprising four retrospective studies, one prospective and two case reports...
March 1, 2024: Dentistry Journal
https://read.qxmd.com/read/38531292/synchronous-nasal-rhinosporidiosis-and-inverted-papilloma-in-a-paediatric-patient-in-dodoma-tanzania-case-report
#2
Zephania Saitabau Abraham, Francis Zerd, Benard John Mnguruta, Chrispin Dickson Mgute, Aveline Aloyce Kahinga
INTRODUCTION: Nasal rhinosporidiosis refers to a rare chronic granulomatous disease caused by Rhinosporidium seeberi. It affects the mucous membrane of sites such as nasopharynx, conjunctiva and palate. Inverted papillomas are relatively rare and are benign epithelial tumors of the nasal cavity that are locally aggressive, exhibit recurrence tendency and malignant transformation. Both entities are very rare in our setting and this is perhaps the first documented case in Tanzania. CASE PRESENTATION: The patient was a 7-year old boy with a 1-year history of left-sided nasal obstruction and intermittent epistaxis for 6 months...
March 23, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38528300/evaluation-of-immunogenicity-and-protective-efficacy-of-bacteriophage-conjugated-haemagglutinin-based-subunit-vaccine-against-equine-influenza-virus-in-a-murine-model
#3
JOURNAL ARTICLE
Ramesh Kumar, Bidhan Chandra Bera, Taruna Anand, Selvaraj Pavulraj, Manu Kurian Mathew, R P Gupta, Bhupendra Nath Tripathi, Nitin Virmani
Equine influenza (EI) is a highly contagious acute respiratory disease of equines caused by the H3N8 subtype of Influenza A virus i.e. equine influenza virus (EIV). Vaccination is an important and effective tool for the control of EI in equines. Most of the commercial influenza vaccines are produced in embryonated hen's eggs which has several inherent disadvantages. Hence, subunit vaccine based on recombinant haemagglutinin (HA) antigen, being the most important envelope glycoprotein has been extensively exploited for generating protective immune responses, against influenza A and B viruses...
March 26, 2024: Veterinary Research Communications
https://read.qxmd.com/read/38522747/peritoneal-dialysis-associated-peritonitis-caused-by-neisseria-sicca-a-case-report-and-literature-review
#4
Mengshuang Zhang, Tian Yang, Xin Yin, GuiXia Li, XuZhan Zhang, Di Xie, Chen Chen
Neisseria sicca, a Gram-negative diplococcus commonly found in the nasopharynx as part of normal bacterial flora, is typically non-pathogenic but has been associated with various diseases including endocarditis, conjunctivitis, pneumonia and meningitis (Jeurissen et al., 2006; Kozlova et al., 2020; Alcid, 1980; Carter et al., 2007). In this report, we present a case of peritonitis in a patient undergoing peritoneal dialysis caused by N. sicca and review the literature on Neisseria-associated peritonitis.
March 22, 2024: Indian Journal of Medical Microbiology
https://read.qxmd.com/read/38517113/higher-area-deprivation-index-is-associated-with-poorer-local-control-and-overall-survival-in-non-metastatic-nasopharyngeal-carcinoma
#5
JOURNAL ARTICLE
Nauman H Malik, Mackenzie Montero, Jie Jane Chen, Sumi Sinha, Sue S Yom, Jason W Chan
BACKGROUND: Neighborhood socioeconomic deprivation impacts outcomes in various cancers. We examined this association in nasopharyngeal carcinoma (NPC) patients using the area deprivation index (ADI). METHODS: We conducted a single-institution retrospective cohort study on NPC patients treated with definitive radiotherapy from 1980 to 2023. ADI was used as the primary exposure measure. Higher ADI indicates higher levels of socioeconomic deprivation. RESULTS: Of 561 patients, those with higher ADI (6-10 vs...
March 22, 2024: Head & Neck
https://read.qxmd.com/read/38516415/central-hyperthyroidism-due-to-an-ectopic-tsh-secreting-pituitary-tumor-a-case-report-and-literature-review
#6
Chonggui Zhu, Tong Liu, Haonan Yu, Lina Chang, Xiaona Zhang, Jia Yao, Geng Zhang, Qiusong Chen, Qing He, Ming Liu
Ectopic thyroid-stimulating hormone (TSH)-secreting tumors are extremely rare, with only 15 reported cases in the literature. Herein, we described a 60-year-old female patient with thyrotoxicosis and elevated or unsuppressed levels of TSH. Family history and laboratory and genetic tests did not support a diagnosis of resistance to thyroid hormone (RTH). Given the unsuppressed TSH, TSH-secreting tumor was suspected, and magnetic resonance imaging (MRI) of the pituitary gland was performed. Surprisingly, the MRI scans revealed a nodule in the nasopharynx rather than a pituitary tumor in the sella region...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38514352/streptococcus-pneumoniae-as-a-colonizing-agent-of-the-nasopharynx-oropharynx-in-adults-a-systematic-review-and-meta-analysis
#7
REVIEW
Julián Lozada, Juan Olivella Gómez, Cristian C Serrano-Mayorga, André Emilio Viñán Garcés, Valeria Enciso, Lina Mendez-Castillo, Alejandro Acosta-González, Ingrid G Bustos, Yuli V Fuentes, Elsa D Ibáñez-Prada, Ana M Crispin, María C Delgado-Cañaveral, Lina María Morales Celis, Diego Jaimes, Paul Turner, Luis Felipe Reyes
BACKGROUND: Streptococcus pneumoniae (Spn) is a commensal pathogen that usually colonizes the upper respiratory tract of children. Likewise, Spn colonization has been considered a critical factor in the development of pneumococcal invasive disease. However, Spn prevalence in adults remains unclear. This study performs a systematic review and meta-analysis to explore the prevalence of Spn Nasopharynx - Oropharynx Colonization (NOC) in adults. METHODS: A Systematic review of scientific databases was utilized to identify eligible studies that follow strict selection criteria...
March 20, 2024: Vaccine
https://read.qxmd.com/read/38514159/nasogastric-tube-placement-perforating-the-nasopharynx-causing-mediastinal-passage-and-feeding-into-the-pleural-space
#8
JOURNAL ARTICLE
Muhammad Zafran, Rebecca Crook, Alexander Tuck, Atmadeep Banerjee
A mid-60s female with known primary progressive multiple sclerosis was admitted to our hospital with aspiration pneumonia. Due to reduced consciousness, a nasogastric (NG) tube was inserted for feeding. A chest x-ray (CXR) report from a thoracic radiologist confirmed an atypical tip position due to a hiatus hernia but concluded it was almost certainly within the stomach. However, after deteriorating on feed commencement, a CT scan of the chest confirmed the tube had perforated the nasopharynx and run parallel to the oesophagus through the mediastinum into the right pleural space...
March 21, 2024: BMJ Case Reports
https://read.qxmd.com/read/38513311/twelve-years-after-the-french-national-network-on-rare-head-and-neck-tumours-refcor
#9
JOURNAL ARTICLE
Cassandre Gasne, Sarah Atallah, Etienne Dauzier, Juliette Thariat, Nicolas Fakhry, Benjamin Verillaud, Marion Classe, Sebastien Vergez, Antoine Moya-Plana, Valerie Costes-Martineau, Christian Righini, Ludovic de Gabory, Laurence Digue, Charles Dupin, François Régis Ferrand, Caroline Even, Bertrand Baujat
BACKGROUND: Rare cancers constitute less than 10% of head and neck cancers and lack sufficient evidence for standardized care. The French Rare Head and Neck Cancer Expert Network (REFCOR) as established a national database to collect data on these rare cancers. This study aims to describe patient and tumour characteristics in this database. METHODS: Prospective data collection was conducted across multiple centers. Survival analyses were performed using Kaplan Meier method and Log Rank test...
March 20, 2024: Oral Oncology
https://read.qxmd.com/read/38508883/surgical-management-of-pediatric-obstructive-sleep-apnea-beyond-adenotonsillectomy-the-nose-nasopharynx-and-palate
#10
REVIEW
Nicholas R Lenze, Suhas R Bharadwaj, Christina M Baldassari, Erin M Kirkham
While adenotonsillectomy is the primary treatment of pediatric obstructive sleep apnea (OSA), persistent OSA after surgery is common and may be due to residual obstruction at the nose, nasopharynx, and/or palate. Comprehensive evaluation for persistent pediatric OSA ideally includes clinical examination (with or without awake nasal endosocpy) as well as drug-induced sleep endoscopy in order to accurately identify sources of residual obstruction. Depending on the site of obstruction, some of the surgical management options include submucous inferior turbinate resection, septoplasty, adenoidectomy, and expansion sphincter pharyngoplasty...
March 19, 2024: Otolaryngologic Clinics of North America
https://read.qxmd.com/read/38500504/detection-of-infectious-sars-cov-2-in-ocular-samples-is-linked-to-viral-load-in-the-nasopharynx
#11
JOURNAL ARTICLE
Janine Kimpel, Annika Rössler, David Bante, Wegene Borena, Dorothee von Laer, Claus Zehetner, Teresa Rauchegger, Stefanie Seiwald, Barbara Falkensammer
INTRODUCTION: SARS-CoV-2 is known to infect respiratory tissue cells. However, less is known about infection of ocular tissue and potential infectivity of lacrimal fluid. With this study, we want to compare viral loads in eye and nasopharyngeal swabs and analyze these for infectious virus. METHODS: Between May 2020 and April 2021 ocular and nasopharyngeal swabs were collected from 28 SARS-CoV-2 infected patients treated on the corona virus disease 2019 (COVID-19)-ward of the University Hospital of Innsbruck, Austria...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38484958/phenotypic-and-molecular-characterization-of-multi-drug-resistant-klebsiella-spp-isolates-recovered-from-clinical-settings
#12
JOURNAL ARTICLE
Hassan Diab, Kelven Rahy, Tamima Jisr, Mira El Chaar, Edmond Abboud, Sima Tokajian
Klebsiella pneumoniae is a Gram-negative bacterium that colonizes the gastrointestinal tract and nasopharynx with many being linked to nosocomial infections. Extended-spectrum β-lactamases (ESBL)-producing and carbapenem-resistant K. pneumoniae is recognized by the World Health Organization (WHO) as a critical public health concern. In this study, whole-genome sequencing (WGS) - based analysis was performed to understand the molecular epidemiology of multi-drug resistant Klebsiella spp. clinical isolates...
March 12, 2024: Infection, Genetics and Evolution
https://read.qxmd.com/read/38482204/the-promising-role-of-mirnas-in-radioresistance-and-chemoresistance-of-nasopharyngeal-carcinoma
#13
REVIEW
Haoyuan Xu, Wanpeng Li, Dehui Wang
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor that develops in the nasopharynx. It has a distinct ethnic and geographical distribution, and emerging evidence suggests that it is an ecological disease. Most patients respond well to radiation combined with chemotherapy as the primary treatment for NPC. However, some patients will eventually develop radio resistance and chemoresistance, resulting in recurrence and metastasis, which is a primary cause of poor prognosis. The processes underlying radio resistance and chemoresistance in NPC are complex and unknown...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38481587/chordoma-of-the-oropharynx
#14
Almedina Ramas, Merima Kasumovic, Sabrina Uscupsic, Majda Mujic, Lejla Tokic
BACKGROUND: Chordoma is a rare malignant neoplasm that predominantly arises from the axial skeleton, but can also develop in unusual locations. However, there are also rare cases of "NOS" chordoma involving the oropharyx and epithelial-myoepithelial carcinoma of the parotid gland in the same patient. According to contemporary research, chordoma is a rare malignant neoplasm that arises from the embryonic remnants of the notochord. and typically involves the clivus, sacrococcygeal bones or vertebrae...
2024: Medical Archives
https://read.qxmd.com/read/38481096/primary-cutaneous-nut-carcinoma-with-brd4-nutm1-fusion
#15
Ahmed Shah, Adrian Box, Thomas Brenn, Ashley Flaman
Nuclear protein in testis (NUT) carcinoma, molecularly defined by the NUTM1 gene rearrangement, is most commonly reported in young adults in the sinonasal tract, nasopharynx, or thorax. At these sites, NUT carcinoma is an extremely aggressive malignancy with dismal prognosis. Recently, five cases of primary cutaneous NUT adnexal carcinoma have been reported with BRD3 and NSD3 fusion partners. Although NUT adnexal carcinomas are shown to have metastatic potential, they may behave less aggressively than extracutaneous NUT carcinomas...
March 13, 2024: Journal of Cutaneous Pathology
https://read.qxmd.com/read/38480081/laser-assisted-retropharyngeal-rigid-nasopharyngoscopy-in-dogs
#16
REVIEW
Boel A Fransson
This article reviews minimally invasive approaches to the nasopharynx. It also introduces a novel approach, transbuccal retrograde rigid pharyngoscopy, and describes three cases in which this approach was used.
March 12, 2024: Veterinary Clinics of North America. Small Animal Practice
https://read.qxmd.com/read/38473281/unfolding-the-complexity-of-exosome-cellular-interactions-on-tumour-immunity-and-their-clinical-prospects-in-nasopharyngeal-carcinoma
#17
REVIEW
Paak-Ting Chak, Ngar-Woon Kam, Tsz-Ho Choi, Wei Dai, Dora Lai-Wan Kwong
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy situated in the posterolateral nasopharynx. NPC poses grave concerns in Southeast Asia due to its late diagnosis. Together with resistance to standard treatment combining chemo- and radiotherapy, NPC presents high metastatic rates and common recurrence. Despite advancements in immune-checkpoint inhibitors (ICIs) and cytotoxic-T-lymphocytes (CTLs)-based cellular therapy, the exhaustive T cell profile and other signs of immunosuppression within the NPC tumour microenvironment (TME) remain as concerns to immunotherapy response...
February 24, 2024: Cancers
https://read.qxmd.com/read/38468658/successful-use-of-a-patient-specific-3d-printed-biomodel-as-surgical-guide-for-excision-of-juvenile-nasopharyngeal-angiofibroma-extending-to-skull-base-a-case-report
#18
Fahad Zahid, Ayesha Memon, Moghira Siddiqui, Muhammad Hammad Deewani, Osama Asif, Amin Javer, Ahsan Ali Khan
BACKGROUND: 3-Dimensional (3D) printing has proven its role in various fields. Recently, 3D printing has also been introduced in the otolaryngology domain. The nasopharynx, paranasal sinuses, and the anterior skull base have a complex anatomy. Critical structures must be delicately protected and preserved during a surgical procedure. It is, therefore, very important for the surgeon to have an excellent spatial understanding of the complex surgical field that is being traversed. CASE DESCRIPTION: Our case is of a 19-year-old male with a 2-month history of recurrent epistaxis, nasal blockage, and headache...
2024: Surgical Neurology International
https://read.qxmd.com/read/38464518/streptococcal-infection-and-autoimmune-diseases
#19
REVIEW
Ayaka Ohashi, Masanori A Murayama, Yoshishige Miyabe, Kazuo Yudoh, Chie Miyabe
Excessive activation of immune cells by environmental factors, such as infection or individual genetic risk, causes various autoimmune diseases. Streptococcus species are gram-positive bacteria that colonize the nasopharynx, respiratory tract, gastrointestinal tract, genitourinary tract, and skin. Group A Streptococcus (GAS) species cause various symptoms, ranging from mild infections, such as tonsillitis and pharyngitis, to serious infections, such as necrotizing fasciitis and streptococcal toxic shock syndrome...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38461886/medium-term-effects-of-rapid-maxillary-expansion-on-nasal-cavity-and-pharyngeal-airway-volumes-considering-age-as-a-factor-a-retrospective-study
#20
JOURNAL ARTICLE
Vincenzo Ronsivalle, Rosalia Leonardi, Manuel Lagravere, Carlos Flore Mir, Cristina Grippaudo, Giulio Alessandri Bonetti, Antonino Lo Giudice
OBJECTIVES: The medium-term effects of rapid maxillary expansion (RME) on nasal cavity (NC) and upper airway (UA) dimensions based on chronological age are still unclear. This retrospective study evaluated the medium-term changes occurring in the NC and pharyngeal airways (PA) after RME in two distinct age-based cohorts. METHODS: This retrospective study included 48 subjects who underwent RME grouped in two cohorts: a 6-9-year-old group (EEG group: early expansion group - 25 subjects) and an 11-14-year-old group (LEG group: late expansion group - 23 subjects)...
March 8, 2024: Journal of Dentistry
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