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https://www.readbyqxmd.com/read/28222301/impact-of-home-visit-capacity-on-genetic-association-studies-of-late-onset-alzheimer-s-disease
#1
David W Fardo, Laura E Gibbons, Shubhabrata Mukherjee, M Maria Glymour, Wayne McCormick, Susan M McCurry, James D Bowen, Eric B Larson, Paul K Crane
INTRODUCTION: Findings for genetic correlates of late-onset Alzheimer's disease (LOAD) in studies that rely solely on clinic visits may differ from those with capacity to follow participants unable to attend clinic visits. METHODS: We evaluated previously identified LOAD-risk single nucleotide variants in the prospective Adult Changes in Thought study, comparing hazard ratios (HRs) estimated using the full data set of both in-home and clinic visits (n = 1697) to HRs estimated using only data that were obtained from clinic visits (n = 1308)...
February 18, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28222168/fewer-acute-respiratory-infection-episodes-among-patients-receiving-treatment-for-gastroesophageal-reflux-disease
#2
Herng-Ching Lin, Sudha Xirasagar, Shiu-Dong Chung, Chung-Chien Huang, Ming-Chieh Tsai, Chao-Hung Chen
Patients with gastroesophageal reflux disease (GERD) present with comorbid complications with implications for healthcare utilization. To date, little is known about the effects of GERD treatment with a proton-pump inhibitor (PPI) on patients' subsequent healthcare utilization for acute respiratory infections (ARIs). This population-based study compared ARI episodes captured through outpatient visits, one year before and one year after GERD patients received PPI treatment. We used retrospective data from the Longitudinal Health Insurance Database 2005 in Taiwan, comparing 21,486 patients diagnosed with GERD from 2010 to 2012 with 21,486 age-sex matched comparison patients without GERD...
2017: PloS One
https://www.readbyqxmd.com/read/28222118/social-structural-behavioral-and-clinical-factors-influencing-retention-in-pre-exposure-prophylaxis-prep-care-in-mississippi
#3
Trisha Arnold, Lauren Brinkley-Rubinstein, Philip A Chan, Amaya Perez-Brumer, Estefany S Bologna, Laura Beauchamps, Kendra Johnson, Leandro Mena, Amy Nunn
Pre-exposure prophylaxis (PrEP) is a biomedical intervention that can reduce rates of HIV transmission when taken once daily by HIV-negative individuals. Little is understood about PrEP uptake and retention in care among the populations most heavily impacted by the HIV epidemic, particularly among young men who have sex with men (YMSM) in the Deep South. Therefore, this study explored the structural, social, behavioral, and clinical factors that affect PrEP use and retention in care among YMSM in Jackson, Mississippi...
2017: PloS One
https://www.readbyqxmd.com/read/28221282/characteristics-and-triage-of-children-presenting-in-mental-health-crisis-to-emergency-departments-at-detroit-regional-hospitals
#4
Kristen Williams, Amanda R Levine, David M Ledgerwood, Alireza Amirsadri, Leslie H Lundahl
OBJECTIVES: The number of children in the United States utilizing emergency department (ED) services for psychiatric crises is increasing, and psychiatric-related ED visits disproportionately burden hospital resources. Yet, there is limited available information on the epidemiology and outcomes of pediatric mental health emergencies. The present study sought to characterize pediatric mental health-related ED presentations in a large urban center and identify factors predictive of inpatient hospitalization...
February 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28221273/the-association-between-immigration-status-and-office-based-medical-provider-visits-for-cancer-patients-in-the-united-states
#5
Yang Wang, Fernando A Wilson, Li-Wu Chen
OBJECTIVES: We examined differences in cancer-related office-based provider visits associated with immigration status in the United States. METHODS: Data from the 2007-2012 Medical Expenditure Panel Survey and National Health Interview Survey included adult patients diagnosed with cancer. Univariate analyses described distributions of cancer-related office-based provider visits received, expenditures, visit characteristics, as well as demographic, socioeconomic, and health covariates, across immigration groups...
February 17, 2017: Medical Care
https://www.readbyqxmd.com/read/28221267/health-related-quality-of-life-and-its-predictors-among-transfusion-dependent-thalassemia-patients
#6
Gulen Tuysuz, Funda Tayfun
PURPOSE: With regular blood transfusions and modern medical management strategies, transfusion-dependent thalassemia (TDT) patients are currently living into adulthood, but they still suffer from the chronicity of the disease and its complications. This study was aimed to assess the health-related quality of life (HRQoL) scores in pediatric TDT patients compared with healthy controls. PATIENTS AND METHODS: The PedsQL 4.0 Generic Core Scales were administered to 80 pediatric TDT patients (aged 5 to 18 y, child self-report) and their parents (parent-proxy report), as well as age-matched and sex-matched healthy controls (80 participants and their parents)...
February 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28221197/physical-activity-and-cognitive-function-among-older-adults-with-hypertension
#7
Emily Frith, Paul D Loprinzi
OBJECTIVE: We evaluated the specific association between physical activity and cognitive function among a national sample of the broader US adult population with evidence of systemic hypertension. METHODS: Data from the 1999-2002 National Health and Nutrition Examination Survey were used to identify 1554 older adults, aged 60-85 years, with evidence of hypertension. The Digit Symbol Substitution Test (DSST) was used to assess cognitive function tasks of pairing and free recall among participants...
February 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28221138/-epidemiology-of-urinary-lithiasis-in-spain-new-scenarios
#8
Julia Carrasco Valiente, Enrique Gómez Gómez, María José Requena Tapia
Renal lithiasis is one of the most common disorders in modern society, constituting an important health problem that associates a great economic burden. The nature of stone disease varies according to age and sex, being also influenced by dietary and lifestyle factors, and climatic variations among others. In spite of the advances made in the management of this pathology, it continues being a disease with a high recurrence rate. In recent years, several studies have pointed out that its prevalence is rising especially in developed countries...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28220736/antibiotic-prescription-patterns-of-south-african-general-medical-practitioners-for-treatment-of-acute-bronchitis
#9
N B Q Ncube, G C Solanki, T Kredo, R Lalloo
BACKGROUND: Antibiotic resistance is a significant public health problem. Prudent use of antibiotics is crucial in reducing this resistance. Acute bronchitis is a common reason for consultations with general medical practitioners, and antibiotics are often prescribed even though guidelines recommend not prescribing them for uncomplicated acute bronchitis. OBJECTIVE: To analyse the antibiotic prescription patterns of South African (SA) general medical practitioners in the treatment of acute bronchitis...
January 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28220606/lamarck-rises-from-his-grave-parental-environment-induced-epigenetic-inheritance-in-model-organisms-and-humans
#10
Yan Wang, Huijie Liu, Zhongsheng Sun
Organisms can change their physiological/behavioural traits to adapt and survive in changed environments. However, whether these acquired traits can be inherited across generations through non-genetic alterations has been a topic of debate for over a century. Emerging evidence indicates that both ancestral and parental experiences, including nutrition, environmental toxins, nurturing behaviour, and social stress, can have powerful effects on the physiological, metabolic and cellular functions in an organism...
February 20, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28220585/sleep-duration-is-associated-with-body-fat-and-muscle-mass-and-waist-to-height-ratio-beyond-conventional-obesity-parameters-in-korean-adolescent-boys
#11
Ga Eun Nam, Kyungdo Han, Do Hoon Kim, Jee Hyun Lee, Won Hee Seo
While evidence has supported a strong association between sleep duration and obesity globally, results from studies of children and adolescents have been conflicting, and information about a sex-specific association has been limited. This study aimed to investigate the association of sleep duration with various parameters of obesity among South Korean adolescents. This population-based, cross-sectional study analysed the data obtained from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2009 and 2010...
February 21, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28220553/african-american-fathers-perspectives-on-facilitators-and-barriers-to-father-son-sexual-health-communication
#12
Schenita D Randolph, Tanya Coakley, Jeffrey Shears, Roland J Thorpe
African-American males ages 13 through 24 are disproportionately affected by sexually transmitted infections (STIs) and human immunodeficiency virus (HIV), accounting for over half of all HIV infections in this age group in the United States. Clear communication between African-American parents and their youth about sexual health is associated with higher rates of sexual abstinence, condom use, and intent to delay initiation of sexual intercourse. However, little is known about African-American fathers' perceptions of what facilitates and inhibits sexual health communication with their preadolescent and adolescent sons...
February 21, 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/28220453/epidemiology-of-sepsis-in-catalonia-analysis-of-incidence-and-outcomes-in-a-european-setting
#13
Juan Carlos Yébenes, Juan Carlos Ruiz-Rodriguez, Ricard Ferrer, Montserrat Clèries, Anna Bosch, Carol Lorencio, Alejandro Rodriguez, Xavier Nuvials, Ignacio Martin-Loeches, Antoni Artigas
BACKGROUND: Up-to-date identification of local trends in sepsis incidence and outcomes is of considerable public health importance. The aim of our study was to estimate annual incidence rates and in-hospital mortality trends for hospitalized patients with sepsis in a European setting, while avoiding selection bias in relation to different complexity hospitals. METHODS: A large retrospective analysis of a 5-year period (2008-2012) was conducted of hospital discharge records obtained from the Catalan Health System (CatSalut) Minimum Basic Data Set for Acute-Care Hospitals (a mandatory population-based register of admissions to all public and private acute-care hospitals in Catalonia)...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28220310/network-centrality-and-geographical-concentration-of-social-and-service-venues-that-serve-young-men-who-have-sex-with-men
#14
Kayo Fujimoto, Rolf Turner, Lisa M Kuhns, Ju Yeong Kim, Jing Zhao, John A Schneider
This study examines network centrality of inter-venue networks formed by collaboration, competition, and sponsorship relationships among venues that serve young men who have sex with men (MSM) aged 16-29 years in relation to their geographical concentrations in Chicago, Illinois, and Houston, Texas. Our data on the physical venues comprised 116 venues in Chicago and 102 venues in Houston. We examined the relationship between the network centrality of different relations and the geographical intensity among these venues, and considered neighborhood-level socioeconomic determinants of health...
February 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28220219/-the-way-from-cost-approval-to-bariatric-surgery-analysis-of-resource-utilization-in-a%C3%A2-maximum-care-hospital
#15
F Nickel, C Tapking, U Zech, K Huennemeyer, A T Billeter, P C Müller, H G Kenngott, B P Müller-Stich, L Fischer
BACKGROUND: Morbid obesity is a medical and economic challenge. Patients who have the indications for bariatric surgery face a long way from the first visit until surgery and a high utilization of resources is required. OBJECTIVES: The present study aimed to evaluate labor costs and labor time required to supervise obese patients from their first visit until preparation of a bariatric report to ask for cost acceptance of bariatric surgery from their health insurance...
February 20, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28220080/validation-of-a-method-for-the-assessment-of-urinary-neopterin-levels-to-monitor-health-status-in-non-human-primate-species
#16
Verena Behringer, Jeroen M G Stevens, Fabian H Leendertz, Gottfried Hohmann, Tobias Deschner
Determining individual health status is of great importance for a better understanding of life history trade-offs between growth, reproduction, and maintenance. However, existing immunological methods are invasive and therefore not suitable for investigating health status in wild populations. Thus, there is an urgent need for non-invasive methods to assess the immune status of animals. Neopterin is involved in the cell-mediated pathway of the immune response (Th1-type), secreted during the activation of monocytes and macrophages...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28219925/twenty-five-year-alcohol-consumption-trajectories-and-their-association-with-arterial-aging-a-prospective-cohort-study
#17
Darragh O'Neill, Annie Britton, Eric J Brunner, Steven Bell
BACKGROUND: Emerging evidence suggests that arterial stiffness, an important marker of cardiovascular health, is associated with alcohol consumption. However, the role of longer-term consumption patterns in the progression of arterial stiffness over time remains unclear. A longitudinal cohort design was used to evaluate the association between alcohol consumption over 25 years and subsequent changes in arterial stiffness. METHODS AND RESULTS: Data (N=3869; 73% male) were drawn from the Whitehall II cohort study of British civil servants, in which participants completed repeat pulse wave velocity assessments of arterial stiffness across a 4- to 5-year interval...
February 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28219486/mental-health-in-internationally-adopted-adolescents-a-meta-analysis
#18
REVIEW
Kristin Gärtner Askeland, Mari Hysing, Annette M La Greca, Leif Edvard Aarø, Grethe S Tell, Børge Sivertsen
OBJECTIVE: To investigate whether mental health problems differ between internationally adopted adolescents and their non-adopted peers and examine design and sample characteristics that might underlie differences among studies. METHOD: Studies published through August 2015 were collected through Embase, Medline, PsychINFO, Web of Science, ERIC, and Svemed+. Combined effect estimates were calculated using random-effects models. RESULTS: Eleven studies investigating 17,919 adoptees and 1,090,289 non-adopted peers were included in the meta-analysis...
March 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28219411/using-the-hierarchical-ordinal-regression-model-to-analyse-the-intensity-of-urinary-schistosomiasis-infection-in-school-children-in-lusaka-province-zambia
#19
Christopher Simoonga, Lawrence N Kazembe
BACKGROUND: Urinary schistosomiasis has been a major public health problem in Zambia for many years. However, the disease profile may vary in different locale due to the changing ecosystem that contributes to the risk of acquiring the disease. The objective of this study was to quantify risk factors associated with the intensity of urinary schistosomiasis infection in school children in Lusaka Province, Zambia, in order to better understand local transmission. METHODS: Data were obtained from 1 912 school children, in 20 communities, in the districts of Luangwa and Kafue in Lusaka Province...
February 21, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28219322/a-screening-program-to-test-and-treat-for-helicobacter-pylori-infection-cost-utility-analysis-by-age-sex-and-ethnicity
#20
Andrea M Teng, Giorgi Kvizhinadze, Nisha Nair, Melissa McLeod, Nick Wilson, Tony Blakely
BACKGROUND: The World Health Organization recommends all countries consider screening for H. pylori to prevent gastric cancer. We therefore aimed to estimate the cost-effectiveness of a H. pylori serology-based screening program in New Zealand, a country that includes population groups with relatively high gastric cancer rates. METHODS: A Markov model was developed using life-tables and morbidity data from a national burden of disease study. The modelled screening program reduced the incidence of non-cardia gastric cancer attributable to H...
February 20, 2017: BMC Infectious Diseases
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