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Chronic pain psychiatric

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https://www.readbyqxmd.com/read/29626076/predicting-opioid-use-disorder-in-patients-with-chronic-pain-who-present-to-the-emergency-department
#1
Robert Andrew Gardner, Kori L Brewer, Dennis B Langston
BACKGROUND: Emergency department (ED) patients with chronic pain challenge providers to make quick and accurate assessments without an in-depth pain management consultation. Emergency physicians need reliable means to determine which patients may receive opioid therapy without exacerbating opioid use disorder (OUD). METHODS: Eighty-nine ED patients with a chief complaint of chronic pain were enrolled. Researchers administered questionnaires and reviewed medical and state prescription monitoring database information...
April 6, 2018: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/29621539/molecular-determinants-of-kv7-1-kcne1-channel-inhibition-by-amitriptyline
#2
Kathya Villatoro-Gómez, David O Pacheco-Rojas, Eloy G Moreno-Galindo, Ricardo A Navarro-Polanco, Martin Tristani-Firouzi, Dimitris Gazgalis, Meng Cui, José A Sánchez-Chapula, Tania Ferrer
Amitriptyline (AMIT) is a compound widely prescribed for psychiatric and non- psychiatric conditions including depression, migraine, chronic pain, and anorexia. However, AMIT has been associated with risks of cardiac arrhythmia and sudden death since it can induce prolongation of the QT interval on the surface electrocardiogram and torsade de pointes ventricular arrhythmia. These complications have been attributed to the inhibition of the rapid delayed rectifier potassium current (IKr ). The slow delayed rectifier potassium current (IKs ) is the main repolarizing cardiac current when IKr is compromised and it has an important role in cardiac repolarization at fast heart rates induced by an elevated sympathetic tone...
April 2, 2018: Biochemical Pharmacology
https://www.readbyqxmd.com/read/29608126/gender-differences-in-the-prevalence-of-fibromyalgia-and-in-concomitant-medical-and-psychiatric-disorders-a-national-veterans-health-administration-study
#3
Caroline A Arout, Mehmet Sofuoglu, Lori A Bastian, Robert A Rosenheck
BACKGROUND: Fibromyalgia is a poorly understood, chronically disabling pain syndrome. While research has focused on its clinical presentation and treatment, less is known about fibromyalgia's clinical epidemiology in real-world healthcare systems. Gender differences have been difficult to study because relatively few males are diagnosed with fibromyalgia. METHODS: Veterans Health Administration (VHA) patients diagnosed with fibromyalgia nationwide in FY 2012 were compared to Veterans with other pain diagnoses on sociodemographic characteristics, medical and psychiatric diagnoses, health service use, and opioid and psychotropic prescription fills...
April 2, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29573030/treatment-course-and-its-predictors-in-patients-with-somatoform-disorders-a-routine-outcome-monitoring-study-in-secondary-psychiatric-care
#4
I V E Carlier, D H Andree Wiltens, Y R van Rood, T van Veen, J Dekker, A M van Hemert
AIM: Somatoform disorders are common and often chronic. It would be helpful to distinguish those patients who are likely to have a positive treatment course from those who are likely to follow a negative course. Such studies of different somatoform disorders are scarce, especially in secondary psychiatric care. This study examined the 6-month treatment course of psychological, physical symptoms, and functioning, and its predictors in a naturalistic sample of secondary psychiatric care outpatients with somatoform disorders...
March 23, 2018: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29538554/-low-back-pain-among-adolescents-in-the-semiarid-region-results-of-a-population-census-in-the-city-of-caracol-state-of-piau%C3%A3-brazil
#5
Rodrigo Dalke Meucci, Angélica Ozório Linhares, Daniel Wenceslau Votto Olmedo, Ewerton Luiz Porto Cousin Sobrinho, Vlanice Madruga Duarte, Juraci Almeida Cesar
The scope of this article is to assess low back pain prevalence and associated factors in the last 12 months among adolescents in a city in the south of the State of Piauí. It was a cross-sectional study which included 1,112 adolescents aged 13-19 in the city of Caracol, Piauí. Demographic, socio-economic, nutritional, behavioral and comorbidty characteristics were investigated. The outcome was the occurrence of low back pain (LBP) in the last 12 months. The outcome prevalence was calculated in accordance with independent variables...
March 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29528599/-transcranial-direct-current-stimulation-tdcs-psychiatric-use
#6
C Kornreich, P Cole, H Kajosch
Transcranial Direct Current Stimulation (tDCS) is a cheap, easy to use, and relatively safe noninvasive brain stimulation technique. It is increasingly used in several indications in psychiatry and neurology, mainly for depression, chronic pain and cognitive decline due to degenerative brain diseases. Its efficacy is probable in depression and must still be confirmed in numerous other indications. Lowcost devices for the general public are easy to find on the internet and are frequently used for non-therapeutic indications, like the improvement of video gamers' performances...
2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29527298/response-heterogeneity-challenges-for-personalised-medicine-and-big-data-approaches-in-psychiatry-and-chronic-pain
#7
Agnes Norbury, Ben Seymour
Response rates to available treatments for psychological and chronic pain disorders are poor, and there is a considerable burden of suffering and disability for patients, who often cycle through several rounds of ineffective treatment. As individuals presenting to the clinic with symptoms of these disorders are likely to be heterogeneous, there is considerable interest in the possibility that different constellations of signs could be used to identify subgroups of patients that might preferentially benefit from particular kinds of treatment...
2018: F1000Research
https://www.readbyqxmd.com/read/29519968/-cortical-midline-structures-self-and-pain
#8
Shigeyuki Kan, Satoru Miyauchi
Emerging evidence indicates that cortical midline structures (CMS) (which consist of the orbitomedial prefrontal cortex (OMPFC), dorsomedial prefrontal cortex (DMPFC), anterior cingulate cortex (ACC), and precuneus/posterior cingulate cortex (pC/PCC)) have a critical role in generating a model of the self. These regions also serve as hub regions for the default mode network (DMN) or salience network (SN). Furthermore, regions of the CMS overlap with pain-related regions such as the so-called "pain matrix," suggesting that pain has unique attributes compared to other sensations like vision...
March 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29513392/cannabis-based-medicines-for-chronic-neuropathic-pain-in-adults
#9
REVIEW
Martin Mücke, Tudor Phillips, Lukas Radbruch, Frank Petzke, Winfried Häuser
BACKGROUND: This review is one of a series on drugs used to treat chronic neuropathic pain. Estimates of the population prevalence of chronic pain with neuropathic components range between 6% and 10%. Current pharmacological treatment options for neuropathic pain afford substantial benefit for only a few people, often with adverse effects that outweigh the benefits. There is a need to explore other treatment options, with different mechanisms of action for treatment of conditions with chronic neuropathic pain...
March 7, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29504088/psychiatry-and-pain-management-at-the-intersection-of-chronic-pain-and-mental-health
#10
REVIEW
Jenna Goesling, Lewei A Lin, Daniel J Clauw
PURPOSE OF REVIEW: Chronic pain impacts millions of people in the USA. At the heart of the problem of chronic pain remains the complex psychosocial aspects associated with living with chronic pain. Given the overlap between chronic pain and mental health, a promising treatment approach is to improve how we integrate psychiatry into pain management. RECENT FINDINGS: Treatment of chronic pain and comorbid mental health issues requires a multidisciplinary approach...
March 5, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29503232/potentially-fatal-outcomes-associated-with-clozapine
#11
Kevin J Li, Ronald J Gurrera, Lynn E Delisi
Clozapine has been shown to be the most efficacious therapy for treatment resistant schizophrenia, estimated at one third of all schizophrenia cases. There is significant morbidity and mortality associated with clozapine including risk of agranulocytosis, aspiration pneumonia, bowel ischemia, myocarditis, seizures, and weight gain. Here we present a case of a 62-year-old man with chronic paranoid schizophrenia refractory to numerous antipsychotics who was started on clozapine therapy during an acute inpatient psychiatric admission...
March 1, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29486806/acute-general-hospital-admissions-in-people-with-serious-mental-illness
#12
Nishamali Jayatilleke, Richard D Hayes, Chin-Kuo Chang, Robert Stewart
BACKGROUND: Serious mental illness (SMI, including schizophrenia, schizoaffective disorder, and bipolar disorder) is associated with worse general health. However, admissions to general hospitals have received little investigation. We sought to delineate frequencies of and causes for non-psychiatric hospital admissions in SMI and compare with the general population in the same area. METHODS: Records of 18 380 individuals with SMI aged ⩾20 years in southeast London were linked to hospitalisation data...
February 28, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29482805/comorbidities-in-a-community-sample-of-narcolepsy
#13
Alexander Cohen, Jay Mandrekar, Erik K St Louis, Michael H Silber, Suresh Kotagal
STUDY OBJECTIVE: To assess comorbidities in a community-based cohort of narcolepsy. METHODS: A 2000-2014 community-based narcolepsy cohort was identified in Olmsted County, Minnesota. Records were reviewed by a certified sleep specialist for accuracy of diagnosis, and comorbidities were extracted and analyzed. Comorbidities in narcolepsy subjects, both at diagnosis and upon follow-up, were compared with those in unaffected and age- and sex-matched cohort using conditional logistic regression...
March 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29480047/-low-intensity-evidence-based-cognitive-behavioural-therapy-of-a-patient-with-crohn-s-disease
#14
Dóra Antal-Uram, László Harsányi, Dóra Perczel-Forintos
Inflammatory bowel disease (Crohn's disease and colitis ulcerosa) is a chronic, long-term condition that causes chronic inflammation in the digestive tract, and shows an increasing incidence and prevalence worldwide. Changes in disease activity over time affect psychological distress which increases the risk of exacerbations. Beside somatic symptoms (such as abdominal pain, diarrhoea and weight loss), psychiatric comorbidity (in particular major depression, anxiety, social phobia) is common in patients with Crohn's disease...
March 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29476270/cognitive-behavioral-therapy-cbt-for-subacute-low-back-pain-a-systematic-review
#15
REVIEW
Timothy Y Mariano, Richard D Urman, Catherine A Hutchison, Robert N Jamison, Robert R Edwards
PURPOSE OF REVIEW: Chronic low back pain (CLBP) is a major source of physical and psychiatric morbidity and mortality, and the current overreliance on opioid analgesics has contributed to a burgeoning epidemic in the USA. Cognitive behavioral therapy (CBT) is an empirically supported treatment for CLBP, but little information exists regarding its potential efficacy for CLBP's precursor condition, subacute low back pain (sALBP), defined here as having a 7-12-week duration. Earlier intervention with CBT at the sALBP stage could produce larger clinical benefits...
February 23, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29456360/clinical-features-and-psychiatric-comorbidity-of-epicrania-fugax
#16
K Rammohan, M M Shyma, Soumitra Das, C Velayudhan Shaji
Background: Epicrania fugax (EF) is a rare newly described primary headache characterized by paroxysms of unilateral pain radiating across one hemicranium. Aim: We aimed to describe 10 new cases of EF and assess the psychiatric comorbidity. Materials and Methods: Cases of EF were identified from patients attending the neurology outpatient department of a tertiary level referral and teaching hospital by the first author during a period extending from January 1, 2015 to April 31, 2017...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29421808/pathophysiology-of-functional-gastrointestinal-disorders-a-holistic-overview
#17
Gerald Holtmann, Ayesha Shah, Mark Morrison
Background and Summary: Traditionally, functional gastrointestinal disorders (FGID), including functional dyspepsia or irritable bowel syndrome (IBS), are defined by more or less specific symptoms and the absence of structural or biochemical abnormalities that cause these symptoms. This concept is now considered to be outdated; if appropriate tests are applied, structural or biochemical abnormalities that explain or cause the symptoms may be found in many patients. Another feature of FGID are the highly prevalent psychiatric comorbidities, such as depression and anxiety...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29420786/one-day-behavioral-intervention-for-distressed-veterans-with-migraine-results-of-a-multimethod-pilot-study
#18
C Huddleston, L Martin, K Woods, L Dindo
Introduction: Migraine, a chronic neurological disorder characterized by episodic severe headache pain and functional impairment, affects approximately 12% of the general US population. Veterans returning from Iraq or Afghanistan have two to four times the incidence of migraine of the general population. Veterans with migraines are more than twice as likely to have comorbid psychiatric conditions as veterans without migraines, with depression and post-traumatic stress disorder being most prevalent...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29410385/functional-magnetic-resonance-imaging-evaluation-of-auricular-percutaneous-electrical-neural-field-stimulation-for-fibromyalgia-protocol-for-a-feasibility-study
#19
Melat Gebre, Anna Woodbury, Vitaly Napadow, Venkatagiri Krishnamurthy, Lisa C Krishnamurthy, Roman Sniecinski, Bruce Crosson
BACKGROUND: Fibromyalgia is a chronic pain state that includes widespread musculoskeletal pain, fatigue, psychiatric symptoms, cognitive and sleep disturbances, and multiple somatic symptoms. Current therapies are often insufficient or come with significant risks, and while there is an increasing demand for non-pharmacologic and especially non-opioid pain management such as that offered through complementary and alternative medicine therapies, there is currently insufficient evidence to recommend these therapies...
February 6, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29392213/diagnostic-confounders-of-chronic-widespread-pain-not-always-fibromyalgia
#20
REVIEW
Winfried Häuser, Serge Perrot, Claudia Sommer, Yoram Shir, Mary-Ann Fitzcharles
Introduction: Chronic widespread pain (CWP) is the defining feature of fibromyalgia (FM), a worldwide prevalent condition. Chronic widespread pain is, however, not pathognomonic of FM, and other conditions may present similarly with CWP, requiring consideration of a differential diagnosis. Objectives: To conduct a literature search to identify medical conditions that may mimic FM and have highlighted features that may differentiate these various conditions from FM...
May 2017: Pain Reports (Baltimore, Md.)
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