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Chronic pain psychiatric

Julie Dupouy, Maryse Lapeyre-Mestre, Stéphane Oustric
No abstract text is available yet for this article.
October 17, 2016: Pain
Hideaki Kaneko, Shuo Zhang, Miho Sekiguchi, Takuya Nikaido, Koshi Makita, Jiro Kurata, Shin-Ichi Konno
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To evaluate activity of the nucleus accumbens (NAc) in response to lumbar mechanical stimulation in patients with chronic low back pain (cLBP) using functional magnetic resonance imaging (fMRI). SUMMARY OF BACKGROUND DATA: Although a modified activity of the NAc was characterized in cLBP patients, its pathological significance has yet to be determined. We hypothesized that NAc activation in response to pain might differ depending on the extent of psychiatric problems, which might be associated with the affective/motivational background of chronic pain...
October 17, 2016: Spine
Yaron Haviv, Avraham Zini, Yoni Etzioni, Valeri Klitinich, Alex Dobriyan, Yair Sharav, Rafael Benoliel, Galit Almoznino
OBJECTIVE: To identify patient and pain characteristics associated with negative impacts on daily life among patients with chronic orofacial pain (COFP). STUDY DESIGN: Medical records of 200 COFP patients were analyzed. RESULTS: Diagnostic categories included temporomandibular disorders (85; 42.7%), headaches (47; 23.6%), neuropathic pain (37; 18.5%), trigeminal neuralgia (16; 8.0%), and painful posttraumatic trigeminal neuropathy (PTTN) (14; 7...
August 27, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Jaak Panksepp
During the past half century of research with preclinical animal models, affective neuroscience has helped identify and illuminate the functional neuroanatomies and neurochemistries of seven primary process, i.e., genetically provided emotional systems of mammalian brains. All are subcortically localized, allowing animal models to guide the needed behavioral and neuroscientific analyses at levels of detail that cannot be achieved through human research, including modern brain imaging. They consist of the following neuronal processes: SEEKING/Enthusiasm, RAGE/Anger, FEAR/Anxiety, sexual LUST/Passion, maternal CARE/Nurturance, separation-distress PANIC/Grief and PLAY/Social Joy...
October 2, 2016: Current Topics in Behavioral Neurosciences
Flávia L Osório, Ana Carolina F Carvalho, Mariana F Donadon, André L Moreno, Omero Polli-Neto
AIM: To compare the prevalence of psychiatric disorders and early emotional traumas between women with chronic pelvic pain (CPP) and healthy women. METHODS: One hundred women in reproductive age, 50 of them had CPP (according to the criteria set by the International Association for Study of Pain), and 50 were considered healthy after the gynecological evaluation. The eligibility criteria were defined as follows: chronic or persistent pain perceived in the pelvis-related structures (digestive, urinary, genital, myofascial or neurological systems)...
September 22, 2016: World Journal of Psychiatry
François Luthi, Adrian Wolfensberger, Philippe Vuistiner, Michel Konzelmann, Chantal Plomb-Holmes, Bertrand Leger
OBJECTIVE: Multiple factors are affecting outcomes after shoulder injuries and there is no general consensus on which are the most decisive. The research questions were: (1) In patients with chronic shoulder pain, what are the psychosocial and biological factors associated with patient-reported outcome measures? (2) What are the psychosocial and biological factors associated with clinician-rated outcome measures? MATERIAL/PATIENTS AND METHODS: In this retrospective cohort study, we collected the following biopsychosocial factors: biological (shoulder diagnosis category, Cumulative Illness Rating Scale (CIRS), Abbreviated Injury Scale (AIS) and INTERMED biological subscale), psychological (psychiatric comorbidity, Hospital Anxiety and Depression Scale (HADS), Pain Catastrophizing Scale (PCS), Tampa Scale of Kinesiophobia (TSK), and INTERMED psychological subscale) and Social (Native Language, educational level, professional qualification, and INTERMED social subscale)...
September 2016: Annals of Physical and Rehabilitation Medicine
Sarah Vigerland, Fabian Lenhard, Marianne Bonnert, Maria Lalouni, Erik Hedman, Johan Ahlen, Ola Olén, Eva Serlachius, Brjánn Ljótsson
Internet-delivered cognitive behavior therapy (ICBT) is a relatively novel treatment format with the potential to increase accessibility of evidence-based care. However, little is known about the feasibility and efficacy of ICBT in children and adolescents. We conducted a comprehensive systematic review and meta-analysis of ICBT for children and adolescents to provide an overview of the field and assess the efficacy of these interventions. A systematic literature search of six electronic databases was performed to identify ICBT intervention studies for children with a psychiatric condition, such as social anxiety disorder, or a somatic condition, such as chronic pain...
September 20, 2016: Clinical Psychology Review
David A Kalmbach, Vivek Pillai, J Todd Arnedt, Christopher L Drake
STUDY OBJECTIVES: We estimated rates of cardiometabolic disease, pain conditions, and psychiatric illness associated with Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) insomnia disorder (current and in remission) and habitual short sleep (fewer than 6 h), and examined the roles of insomnia and short sleep in racial disparities in disease burden between black and non-Hispanic white Americans. METHODS: This epidemiological survey study was cross-sectional...
September 9, 2016: Sleep
Tingting Wang, Ryan T Jones, Jenna M Whippen, Graeme W Davis
The homeostatic modulation of neurotransmitter release, termed presynaptic homeostatic potentiation (PHP), is a fundamental type of neuromodulation, conserved from Drosophila to humans, that stabilizes information transfer at synaptic connections throughout the nervous system. Here, we demonstrate that α2δ-3, an auxiliary subunit of the presynaptic calcium channel, is required for PHP. The α2δ gene family has been linked to chronic pain, epilepsy, autism, and the action of two psychiatric drugs: gabapentin and pregabalin...
September 13, 2016: Cell Reports
Alexandre Heeren, Charlotte Coussement, Élisabeth Colon
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that has undergone intensive research over the past decade with promising results. tDCS is based on the application of weak, direct current over the scalp, leading to cortical hypo- or hyperpolarization according to the specified parameters. Recent studies have shown that tDCS is able to induce potent changes in cortical excitability as well as to elicit long-lasting modifications in brain activity. Over the last decade, tDCS physiological mechanisms of action have been intensively investigated...
August 2016: Médecine Sciences: M/S
Stephen Bruehl, Richard Ohrbach, Sonia Sharma, Eva Widerstrom-Noga, Robert H Dworkin, Roger B Fillingim, Dennis C Turk
UNLABELLED: The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks-American Pain Society Pain Taxonomy (AAPT) is designed to be an evidence-based multidimensional chronic pain classification system that will facilitate more comprehensive and consistent chronic pain diagnoses, and thereby enhance research, clinical communication, and ultimately patient care. Core diagnostic criteria (dimension 1) for individual chronic pain conditions included in the initial version of AAPT will be the focus of subsequent empirical research to evaluate and provide evidence for their reliability and validity...
September 2016: Journal of Pain: Official Journal of the American Pain Society
Declan T Barry, Christopher J Cutter, Mark Beitel, Robert D Kerns, Christopher Liong, Richard S Schottenfeld
OBJECTIVE: Psychiatric comorbidities complicate treatment of patients with chronic pain and opioid use disorder, but the prevalence of specific comorbid psychiatric disorders in this population has not been systematically investigated. METHODS: 170 consecutive participants entering a treatment research program for co-occurring chronic pain and opioid use disorder between March 2009 and July 2013 were evaluated with the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID-I/P) and the Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV)...
August 30, 2016: Journal of Clinical Psychiatry
Eleshia J Morrison, Joseph M Flynn, Jeffrey Jones, John C Byrd, Barbara L Andersen
Chronic lymphocytic leukemia (CLL) is an incurable illness, with some patients requiring no treatment until disease progression. Burden from physical symptoms has been associated with depression, anxiety, and stress in cancer patients. Additionally, patient factors, i.e., individual differences, have been associated with worse psychological outcomes. There are few psychological studies of CLL, with no examination of individual differences. A cross-sectional design studied the covariation of symptom burden with depressive and anxiety symptoms and cancer-specific stress, and tested patients' individual differences as predictors and as moderators...
August 19, 2016: Annals of Hematology
Andrew M McIntosh, Lynsey S Hall, Yanni Zeng, Mark J Adams, Jude Gibson, Eleanor Wigmore, Saskia P Hagenaars, Gail Davies, Ana Maria Fernandez-Pujals, Archie I Campbell, Toni-Kim Clarke, Caroline Hayward, Chris S Haley, David J Porteous, Ian J Deary, Daniel J Smith, Barbara I Nicholl, David A Hinds, Amy V Jones, Serena Scollen, Weihua Meng, Blair H Smith, Lynne J Hocking
BACKGROUND: Chronic pain is highly prevalent and a significant source of disability, yet its genetic and environmental risk factors are poorly understood. Its relationship with major depressive disorder (MDD) is of particular importance. We sought to test the contribution of genetic factors and shared and unique environment to risk of chronic pain and its correlation with MDD in Generation Scotland: Scottish Family Health Study (GS:SFHS). We then sought to replicate any significant findings in the United Kingdom Biobank study...
August 2016: PLoS Medicine
Hans Idenfors, Lotta M J Strömsten, Ellinor Salander Renberg
OBJECTIVE: Many young people contact health services before they harm themselves intentionally. However, they often seek care for non-suicidal or non-psychiatric causes despite having suicidal thoughts. We investigated the non-psychiatric hospital diagnoses received by young people during the year before their first admission to hospital for self-harm. METHODS: From a national register, we selected people who were hospitalised for an episode of self-harm during the period 1999-2009, at which time they were aged 16 to 24...
September 2016: Journal of Psychosomatic Research
A Grimby-Ekman, B Ghafouri, H Sandén, B Larsson, B Gerdle
OBJECTIVE: To test, in this pilot study, whether DHEA-S (Dehydroepiandrosterone, sulfated form) plasma levels are lower among persons with chronic neck pain, compared to control persons, and to investigate the DHEA-S response after a physical exercise. SUBJECTS: Included were 12 persons with chronic neck pain and eight controls without present pain, all 18 and 65 years of age. Exclusion criteria for both groups were articular diseases or tendinosis, fibromyalgia, systemic inflammatory and neuromuscular diseases, pain conditions due to trauma, or severe psychiatric diseases...
August 7, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Alan K Davis, Erin E Bonar, Mark A Ilgen, Maureen A Walton, Brian E Perron, Stephen T Chermack
Psychiatric symptoms, somatic problems, and co-occurring substance use have been associated with medical marijuana consumption among civilian patients with substance use disorders. It is possible that these factors may impact Veterans' ability to engage in or adhere to mental health and substance use disorder treatment. Therefore, we examined whether psychiatric functioning, substance use, and somatic problems were associated with medical marijuana use among Veterans receiving substance use disorder and/or mental health treatment...
December 2016: Addictive Behaviors
Melissa T Stone, Valerie Weed, Ronald J Kulich
Migraine can impact every aspect of a person's functioning. Psychological comorbidities, cognitive constructs, and behavioral responses to pain greatly impact the perception of migraine pain, treatment efficacy and outcome, and overall quality of life and functioning. Current considerations for migraine treatment emphasize the utility of the biopsychosocial model in understanding and treating migraine, noting both the importance of addressing psychological factors such as cognitive beliefs as well as psychiatric comorbidities...
September 2016: Current Pain and Headache Reports
Amy V Jones, James R F Hockley, Craig Hyde, Donal Gorman, Ana Sredic-Rhodes, James Bilsland, Gordon McMurray, Nicholas A Furlotte, Youna Hu, David A Hinds, Peter J Cox, Serena Scollen
Dysmenorrhea is a common chronic pelvic pain syndrome affecting women of childbearing potential. Family studies suggest that genetic background influences the severity of dysmenorrhea, but genetic predisposition and molecular mechanisms underlying dysmenorrhea are not understood. In this study, we conduct the first genome-wide association study to identify genetic factors associated with dysmenorrhea pain severity. A cohort of females of European descent (n = 11,891) aged 18 to 45 years rated their average dysmenorrhea pain severity...
November 2016: Pain
Héléne Staquet, Denis Dupoiron, Edmond Nader, Philippe Menei
Intracerebroventricular (ICV) administration of opioids for control of intractable cancer pain has been used since 1982. We present here our experience of intracerebroventricular administration of pain treatments including ziconotide associated with morphine and ropivacaine for patients resistant to a conventional approach, with nociceptive, neuropathic, or mixed pain. These clinical cases were conducted with patients suffering from refractory pain, more than 6/10 on a numerical pain rating scale (NPRS) while on high-dose medical treatment and/or intolerance with significant side effects from oral medication...
July 2016: Pain Physician
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