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https://www.readbyqxmd.com/read/28651324/preparation-of-activated-carbon-from-molasses-to-ethanol-process-waste-vinasse-and-its-performance-as-adsorbent-material
#1
Omer Kazak, Yasin Ramazan Eker, Haluk Bingol, Ali Tor
Herein, the preparation of activated carbon from waste vinasse by using hydrothermal H2O2 oxidation combined with a two-step pyrolysis process has been described for the first time as a new utilization approach for the waste vinasse. The characterization studies were performed by TGA, FT-IR, Raman spectroscopy, SEM-EDX and gas adsorption measurements. The approach generated a microporous activated carbon with high specific surface area (989m(2)/g) from waste vinasse. After simple experiments on various dye solutions, adsorption performance of the activated carbon was specifically studied on the methylene blue solution as functions of solution pH, contact time, adsorbent amount and reusability...
June 13, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28651322/ozonation-of-tannic-acid-to-model-biomass-pretreatment-for-bioethanol-production
#2
Roi Peretz, Yoram Gerchman, Hadas Mamane
Lignocellulosic biomass is a promising feedstock for ethanol production, but lignin, a polyphenol, hampers the use of enzymes for its saccharification; pretreatment is thus key to preparing such feedstock. Ozonation was previously demonstrated as an effective pretreatment, but claimed to be uneconomical due to the assumed need for lignin mineralization. We analyzed, for the first time, ozonation of highly concentrated tannic acid (TA) solution (60g/L) as a lignin model. Most of the TA disappeared within 3.5h, following triple-phase kinetics with two transition points: at 7min and 60min of ozonation for 0...
June 1, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28651231/evaluation-of-in-vitro-anticancer-activity-of-1-8-cineole-containing-n-hexane-extract-of-callistemon-citrinus-curtis-skeels-plant-and-its-apoptotic-potential
#3
Sowndarya Sampath, Vidhya Veeramani, Gopal Shankar Krishnakumar, Udhayakumar Sivalingam, Suguna Lakshmi Madurai, Rose Chellan
Plants are the source of a variety of secondary metabolites, which are often used in the anticancer activity. Discovering new anticancer drug from herbal source is more important in both biological and pharmacological activities. Hence, the objective of this study is to identify the anticancer agent in Callistemon citrinus (Curtis) Skeels (CC) for the treatment of cancer. Very recently we have reported an increased antioxidant activity in the ethanolic and methanolic extracts (EE and ME) of CC but significantly reduced activity (rather increased cytotoxicity), in the n-hexane extract (HE)...
June 23, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28651135/a-model-biorefinery-for-avocado-persea-americana-mill-processing
#4
Javier A Dávila, Moshe Rosenberg, Eulogio Castro, Carlos A Cardona
This research investigated and evaluated a biorefinery for processing avocado Hass variety into microencapsulated phenolic compounds extract, ethanol, oil and xylitol. Avocado was first characterized for its potential valuable compounds; then, the techno-economic and environmental aspects of the biorefinery were developed and finally the total production costs and potential environmental impact of the proposed biorefinery were investigated. Four scenarios of the biorefinery were evaluated with different extent of mass and energy integration as well as the incorporation of a cogeneration system...
June 15, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28651132/enhanced-acetone-butanol-ethanol-production-from-lignocellulosic-hydrolysates-by-using-starchy-slurry-as-supplement
#5
Ming Yang, Suvi Kuittinen, Jouko Vepsäläinen, Junhua Zhang, Ari Pappinen
This study aims to improve acetone-butanol-ethanol production from the hydrolysates of lignocellulosic material by supplementing starchy slurry as nutrients. In the fermentations of glucose, xylose and the hydrolysates of Salix schwerinii, the normal supplements such as buffer, minerals, and vitamins solutions were replaced with the barley starchy slurry. The ABE production was increased from 0.86 to 14.7g/L by supplementation of starchy slurry in the fermentation of xylose and the utilization of xylose increased from 29% to 81%...
June 8, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28650702/a-case-report-of-methadone-associated-hypoglycemia-in-an-11-month-old-male
#6
Michael S Toce, Margaret A Stefater, David T Breault, Michele M Burns
BACKGROUND: Methadone is a synthetic μ-opioid receptor agonist that is used in the management of pain, neonatal abstinence withdrawal syndrome, and opioid dependence. Overdose can cause miosis, respiratory depression, and central nervous system depression. Rarely, hypoglycemia has been reported. We present the case of an 11-month-old male who developed hypoketotic, hyperinsulinemic, hypoglycemia after an acute, unintentional methadone exposure. CASE DETAILS: The patient was a previously healthy 11-month-old male who presented in respiratory failure...
June 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28650391/proteins-differentially-expressed-in-the-pancreas-of-hepatic-alcohol-dehydrogenase-deficient-deer-mice-fed-ethanol-for-3-months
#7
Kamlesh K Bhopale, Samir M Amer, Lata Kaphalia, Kizhake V Soman, John E Wiktorowicz, Ghulam A Shakeel Ansari, Bhupendra S Kaphalia
OBJECTIVES: The aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase-deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatitis. METHODS: Mice were fed liquid diet containing 3.5 g% ethanol daily for 3 months, and differentially expressed pancreatic proteins were identified by protein separation using 2-dimensional gel electrophoresis and identification by mass spectrometry...
June 22, 2017: Pancreas
https://www.readbyqxmd.com/read/28650336/design-and-content-determination-of-genhuang-dispersible-tablet-herbal-formulation
#8
Rui-Hua Xin, Ge Liang, Ji-Fang Zheng
The aim of the present study was to optimize the shaping technology of the traditional herbal formula Genhuang dispersible tablets, and also establish a method for content determination. The optimal formulation of Genhuang dispersible tablets was determined based on the results of single factor test and orthogonal design test. The disintegration was used as the main study indicator. The proportion of each adjuvant in the optimal formulation consisted of 40% MCC as bulking agent, 15% PVPP and 7% L-HPC as disintegrant, ethanol as adhesive, CSD as lubricant, preparing the dispersible tablets with wet granulation...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28650328/studies-on-self-nanoemulsifying-drug-delivery-system-of-flurbiprofen-employing-long-medium-and-short-chain-triglycerides
#9
Junaid Daar, Ahmad Khan, Jallat Khan, Amjad Khan, Gul Majid Khan
The aim of the study was to successfully design, formulate and evaluate self-nanoemulsifying drug delivery system (SNEDDS) of poorly aqueous soluble drug viz. flurbiprofen using long (LCT), medium (MCT) and short chain triglycerides (SCT). The SNEDDS are thermodynamically stable lipid based drug delivery systems which consist of mixture of oil, surfactant and co-surfactant. Upon aqueous dilution, this mixture produces nano-emulsion spontaneously on slight agitation. The excipients intended to be used were screened for their potential to dissolve the drug and to form clear dispersion upon aqueous dilution...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28650016/prediction-of-1-h-nmr-chemical-shifts-for-clusters-of-imidazolium-based-ionic-liquids
#10
Su Chen, Ekaterina I Izgorodina
Nuclear magnetic resonance (NMR) has been widely used to elucidate the bulk structure of ionic liquids. In this work, we calculated (1)H NMR chemical shifts of 1-ethyl-3-methylimidazolium (C2mim(+)) ionic liquids combined with various anions such as chloride (Cl), tetrafluoroborate (BF4), hexafluorophosphate (PF6), acetate (OAc), trifluoroacetate (TFA), and dicyanamide (DCA). The previously established level of theory, HF/6-311G+(3df,2p), was used for the accurate prediction of NMR chemical shifts both in gas phase and in solvents with varying dielectric constant such as CHCl3 and ethanol...
June 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28649276/a-comparison-of-various-lignin-extraction-methods-to-enhance-the-accessibility-and-ease-of-enzymatic-hydrolysis-of-the-cellulosic-component-of-steam-pretreated-poplar
#11
Dong Tian, Richard P Chandra, Jin-Suk Lee, Canhui Lu, Jack N Saddler
BACKGROUND: Current single-stage delignification-pretreatment technologies to overcome lignocellulosic biomass recalcitrance are usually achieved at the expense of compromising the recovery of the polysaccharide components, particularly the hemicellulose fraction. One way to enhance overall sugar recovery is to tailor an efficient two-stage pretreatment that can pre-extract the more labile hemicellulose component before subjecting the cellulose-rich residual material to a second-stage delignification process...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28649077/hepatoprotective-evaluation-of-aqueous-ethanolic-extract-of-capparis-decidua-stems-in-paracetamol-induced-hepatotoxicity-in-experimental-rabbits
#12
Jalilur Rehman, Naveed Akhtar, Hafiz Muhammad Asif, Sabira Sultana, Mukhtiar Ahmad
Liver diseases are the most common ailment all over the world mostly caused by viruses, toxic chemicals, excessive intake of alcohol, high doses of paracetamol, carbon tetrachloride, chemotherapeutic agents and peroxides oil, etc. There is a great need to assess the scientific basis for the medicinal plants that are claimed to have hepatoprotective activity. We investigate the hepatoprotective effects of aqueous-ethanolic extract of Capparis decidua (Stems) against paracetamol induced liver injury in experimental animals...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649075/hypouricemic-and-nephroprotective-effects-of-total-flavonoids-from-the-residue-of-supercritical-co2-extraction-of-humulus-lupulus-in-potassium-oxonate-induced-mice
#13
Zhen Jing Li, Zhuan Li, Xiao Ying Dong, Lai Feng Lu, Chang Lu Wang
Total flavonoids of Humulus lupulus (TFHL) were prepared using ethanol extraction, liquid-liquid partition and purification with polyamide resin. Different dose of TFHL were orally administered to normal and hyperuricemic mice for 7 days. The xanthine oxidase (XOD) inhibitory activity and hypouricemic effects of TFHL on potassium oxonate-induced hyperuricemic mice were examined. The TFHL showed very potent XOD inhibitory activity with IC50=66.8 μg/mL. At a single oral dose of 100mg/kg TFHL, the serum uric acid levels of hyperuricemic mice significantly decreased (P<0...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649067/pharmacognostic-and-phytochemical-studies-of-zanthoxylum-armatum-dc
#14
- Barkatullah, Muhammad Ibrar, Naveed Muhammad, Ajmal Khan, Shahid Ali Khan, Salman Zafar, Samin Jan, Nadia Riaz, Zain Ullah, Umar Farooq, Javid Hussain
The pharmacognostic and phytochemical investigations on the leaf, stem bark, and fruit of Zanthoxylum armatum were carried out. Macroscopic study of leaf, stem bark, and fruit of Z. armatum revealed some of the characteristic features like size, shape, color, odor and taste of the crude drug. Distinguishing fragments were identified from the powder drug. Leaf, bark, and fruit powder of this plant have higher values of total, acid insoluble, and water soluble ash as compared to the powder of this plant exhausted with ethanol and n- hexane...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649061/effect-of-seaweeds-occurring-at-karachi-coast-on-mosquito-larvae-and-liver-function-in-rats
#15
Khan Hira, Rajput M Tariq, Viqar Sultana, Jehan Ara, Syed Ehteshamul Haque
Seaweeds have been consumed as human food from thousands of years. In this study ethanol extract of 16 different seaweeds were tested for mosquito larvicidal activity against 4th instar larvae of Aedes aegyptii. The ethanol extracts of Padina pavonia and Sargassum ilicifolium caused 50% mortality at 1200ppm concentration. However other seaweeds Halimeda tuna, Ulva lactuca (Chlorophyta), Dictyota dichotoma var intricata, Jolyna laminariodes, Sargassum binderi (Phaeophyta), Melanothamnus afaqhusainii and Solieria robusta (Rhodophyta) showed LC50 at ≈1500 ppm concentration...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28648518/selective-inhibition-of-bet-proteins-reduces-pancreatic-damage-and-systemic-inflammation-in-bile-acid-and-fatty-acid-ethyl-ester-but-not-caerulein-induced-acute-pancreatitis-in-mice
#16
Wei Huang, Andrea C Haynes, Rajarshi Mukherjee, Li Wen, Diane Latawiec, Alexei V Tepikin, David N Criddle, Rab K Prinjha, Nicholas Smithers, Robert Sutton
OBJECTIVES: To evaluate the therapeutic potential of I-BET-762, an inhibitor of the bromodomain and extra-terminal (BET) protein family, in experimental acute pancreatitis (AP). METHODS: AP was induced in mice by retrograde infusion of taurolithocholic acid sulphate into the biliopancreatic duct (TLCS-AP) or two intraperitoneal (i.p.) injections of ethanol and palmitoleic acid 1 h apart (FAEE-AP) or 12 hourly i.p. injections of caerulein (CER-AP). In all treatment groups, I-BET-762 (30 mg/kg, i...
June 10, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28648288/characterization-of-bacillus-megaterium-bacillus-pumilus-and-paenibacillus-polymyxa-isolated-from-a-pinot-noir-wine-from-western-washington-state
#17
Nicolas H von Cosmos, Bruce A Watson, J K Fellman, D S Mattinson, Charles G Edwards
This report provides the first confirmed evidence of Bacillus-like bacteria present in a wine from Washington State. These bacteria were isolated from a 2013 Pinot noir wine whose aroma was sensorially described as being 'dirty' or 'pond scum.' Based on physiological traits and genetic sequencing, three bacterial isolates were identified as Bacillus megaterium (strain NHO-1), Bacillus pumilus (strain NHO-2), and Paenibacillus polymyxa (strain NHO-3). These bacteria grew in synthetic media of low pH (pH 3.5) while some survived ethanol concentrations up to 15% v/v...
October 2017: Food Microbiology
https://www.readbyqxmd.com/read/28647675/abstinence-from-prolonged-ethanol-exposure-affects-plasma-corticosterone-glucocorticoid-receptor-signaling-and-stress-related-behaviors
#18
Sucharita S Somkuwar, Leandro F Vendruscolo, McKenzie J Fannon, Brooke E Schmeichel, Tran Bao Nguyen, Jasmin Guevara, Harpreet Sidhu, Candice Contet, Eric P Zorrilla, Chitra D Mandyam
Alcohol dependence is linked to dysregulation of the hypothalamic-pituitary-adrenal axis. Here, we investigated effects of repeated ethanol intoxication-withdrawal cycles (using chronic intermittent ethanol vapor inhalation; CIE) and abstinence from CIE on peak and nadir plasma corticosterone (CORT) levels. Irritability- and anxiety-like behaviors as well as glucocorticoid receptors (GR) in the medial prefrontal cortex (mPFC) were assessed at various intervals (2h-28d) after cessation of CIE. Results show that peak CORT increased during CIE, transiently decreased during early abstinence (1-11d), and returned to pre-abstinence levels during protracted abstinence (17-27d)...
June 12, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28647568/hepatocyte-derived-macrophage-migration-inhibitory-factor-mediates-alcohol-induced-liver-injury-in-mice-and-patients
#19
Veronica Marin, Kyle Poulsen, Gemma Odena, Megan R McMullen, Jose Altamirano, Pau Sancho-Bru, Claudio Tiribelli, Juan Caballeria, Natalia Rosso, Ramon Bataller, Laura E Nagy
BACKGROUND & AIMS: Macrophage migration inhibitory factor (MIF) is a multi-potent cytokine that contributes to the inflammatory response to injury. MIF is expressed by multiple cell types; however, the cellular source and actions of MIF in alcoholic liver disease (ALD) are not well known. Here we tested the hypothesis that non-myeloid cells, specifically hepatocytes, are an important cellular source of MIF in ALD. METHODS: MIF expression was measured in HuH7 and differentiated THP-1 cells in response to ethanol...
June 21, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28647510/hepatoprotective-effect-of-gan-kang-yaun-against-chronic-liver-injury-induced-by-alcohol
#20
Yuanheng Guo, Qingsheng Zhao, Lili Cao, Bing Zhao
ETHNOPHARMACOLOGICAL RELEVANCE: Gan Kang Yuan (GKY) is a compound medicine formulated on the basis of traditional Chinese medicine (TCM). It was composed of Herba Cistanchis (Roucongrong), Radix Puerariae (Gegen), Radix Astragali (Huangqi), Fructus Schisandrae (Wuweizi) and Radix Glycyrrhizae (Gancao). AIM: The purpose of this study is to research the hepatoprotective effect of GKY against liver injury induced by alcohol, and to elucidate the mechanism of hepatopretective effect...
June 21, 2017: Journal of Ethnopharmacology
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