keyword
https://read.qxmd.com/read/38367544/potentially-inappropriate-medication-use-among-older-adults-with-lower-limb-loss
#21
JOURNAL ARTICLE
Samantha Jeanne Stauffer, Ryan Todd Pohlig, John Robert Horne, Frank Bernard Sarlo, Jaclyn Megan Sions
OBJECTIVE: The aim of this study was to evaluate the prevalence of, and explore factors related to, prescription of potentially inappropriate medications (PIMs) among older adults with lower-limb loss (LLL). METHODS: This was a secondary analysis of a cross-sectional dataset collected through an interdisciplinary limb loss clinic between September 2013 and November 2022. Self-report medication lists were reviewed during in-clinic face-to-face interviews and compared to the American Geriatrics Society Beers Criteria corresponding to the patient's evaluation year...
February 16, 2024: Geriatric Nursing
https://read.qxmd.com/read/38362229/potentially-inappropriate-medications-use-and-associated-factors-among-older-patients-on-follow-up-at-the-chronic-care-clinic-of-hiwot-fana-comprehensive-specialized-hospital-in-eastern-ethiopia
#22
JOURNAL ARTICLE
Shambel Nigussie, Fekade Demeke
BACKGROUND: Potentially inappropriate medications (PIMs) use often cause to poor health outcomes in older patients. There is a dearth of information on PIMS use in this population of patients seeking treatment at Hiwot Fana Comprehensive Specialized Hospital. OBJECTIVE: To assess PIMs use and associated factors among older patients receiving follow-up treatment at the chronic care clinic of Hiwot Fana Comprehensive Specialized Hospital in eastern Ethiopia. METHODS: A retrospective cross-sectional study using medical records of 419 older patients was conducted...
2024: Current Therapeutic Research, Clinical and Experimental
https://read.qxmd.com/read/38326897/prevalence-and-trend-of-central-nervous-system-active-medication-polypharmacy-among-us-commercially-insured-adults-with-vs-without-early-onset-dementia-a-multi-year-cross-sectional-study
#23
JOURNAL ARTICLE
Yu-Jung Jenny Wei, Nistha Shrestha, ChienWei Chiang, Steven T DeKosky
BACKGROUND: Limited data exist on the prevalence and trend of central nervous system (CNS)-active medication polypharmacy among adults with early-onset dementia (EOD) and whether these estimates differ for adults without EOD but with chronic pain, depression, or epilepsy, conditions managed by CNS-active medications. METHODS: A multi-year, cross-sectional study using 2012-2021 MarketScan Commercial Claims data was conducted among adults aged 30 to 64 years with EOD and those without EOD but having a diagnosis of chronic pain, depression, or epilepsy as comparison groups...
February 8, 2024: Alzheimer's Research & Therapy
https://read.qxmd.com/read/38321367/appropriateness-of-direct-oral-anticoagulant-prescribing-in-older-subjects-with-atrial-fibrillation-discharged-from-acute-medical-wards
#24
JOURNAL ARTICLE
Antonio De Vincentis, Luca Soraci, Elena Arena, Angela Sciacqua, Giuseppe Armentaro, Francesco Aucella, Andrea Corsonello, Filippo Aucella, Raffaele Antonelli Incalzi
AIMS: Knowledge on the prescriptive practice of direct oral anticoagulants (DOACs) in older subjects with atrial fibrillation (AF) hospitalized in acute medical wards is limited. This study aimed to evaluate the prevalence and appropriateness of DOAC prescriptions in hospitalized older subjects with AF, discharged from acute medical wards. METHODS: We analysed a cohort of 609 subjects with AF, aged ≥65 years (mean age 85 years) enrolled from 39 geriatric and nephrology wards in Italy...
February 6, 2024: British Journal of Clinical Pharmacology
https://read.qxmd.com/read/38319349/comparing-ags-beers-2019-stopp-version-2-and-eu-7-pim-list-in-portuguese-older-adults-in-primary-health-care
#25
JOURNAL ARTICLE
Daniela A Rodrigues, Maria Teresa Herdeiro, Ramona Mateos-Campos, Adolfo Figueiras, Fátima Roque
PURPOSE: This study aims to identify PIM prevalence in older adults according to the 2019 Beers criteria, Screening Tool of Older Person's Prescriptions version 2 (STOPP v2) criteria, and the Portuguese EU(7)-PIM list and also to analyze the concordance between these criteria. METHODS: A retrospective study was conducted among 1200 Portuguese older adults (≥ 65 years old), users of primary health care. Demographic, clinical, and pharmacological data were collected concerning the period between April 2021 and August 2022...
February 6, 2024: European Journal of Clinical Pharmacology
https://read.qxmd.com/read/38273186/are-lists-of-potentially-inappropriate-medications-associated-with-hospital-readmissions-a-systematic-review
#26
Camille Schwab, Alice Clementz, Agnès Dechartres, Christine Fernandez, Patrick Hindlet
BACKGROUND: Suboptimal prescribing, including the prescription of potentially inappropriate medications (PIM), is frequent in patients aged 65 years and older. PIMs are associated with adverse drug events, which may lead to hospital admissions and readmissions for the most serious cases. Several tools, known as lists of PIMs, can detect suboptimal prescription. OBJECTIVE: This systematic review aimed to identify which lists of PIMs are associated with hospital readmission of older patients...
January 25, 2024: Drugs & Aging
https://read.qxmd.com/read/38273076/prevalence-and-appropriateness-of-polypharmacy-in-older-adults-with-inflammatory-bowel-diseases
#27
JOURNAL ARTICLE
Bharati Kochar, Alison Rusher, Elizabeth Araka, Rachel Glasser, Jennifer Lai, Christine Ritchie, Ashwin N Ananthakrishnan
BACKGROUND: Despite the growing prevalence of older adults with inflammatory bowel diseases (IBD), polypharmacy, an important geriatric construct, is poorly understood. We described polypharmacy and its implications in older adults with IBD. METHODS: In a cross sectional study of adults ≥ 60 years with IBD, we obtained medication lists from the medical record and patients. We assessed medications by the Beer's criteria, anti-cholinergic burden and drug-drug interactions...
January 25, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38258538/potentially-inappropriate-prescriptions-and-potential-prescription-omissions-in-older-people-living-with-hiv
#28
JOURNAL ARTICLE
Jorge Fernández-Fradejas, Eva Delgado-Silveira, Elena González-Burgos, Ana María Álvarez-Díaz, Manuel Vélez-Díaz-Pallarés
OBJECTIVES: This study aimed to determine the prevalence of potentially inappropriate prescriptions (PIPs) and potential prescription omissions (PPOs) in a Spanish cohort of people living with HIV (PLWH) aged ≥65 years and to identify risk factors for the presence of PIPs and PPOs. METHODS: This retrospective cross-sectional study was conducted across 10 public hospitals in the Autonomous Community of Madrid, Spain. Clinical and demographic data were cross-checked against hospital and community pharmacy dispensation registries...
January 23, 2024: HIV Medicine
https://read.qxmd.com/read/38256457/potentially-inappropriate-prescribing-and-potential-prescribing-omissions-and-their-association-with-adverse-drug-reaction-related-hospital-admissions
#29
JOURNAL ARTICLE
Ross Brannigan, John E Hughes, Frank Moriarty, Emma Wallace, Ciara Kirke, David Williams, Kathleen Bennett, Caitriona Cahir
BACKGROUND: This study aimed to determine the prevalence of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) and their association with ADR-related hospital admissions in patients aged ≥ 65 years admitted acutely to the hospital. METHODS: Information on medications and morbidities was extracted from the Adverse Drug Reactions in an Ageing Population (ADAPT) cohort (N = 798: N = 361 ADR-related admissions; 437 non-ADR-related admissions)...
January 6, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38248074/applicability-of-the-ct-radiomics-of-skeletal-muscle-and-machine-learning-for-the-detection-of-sarcopenia-and-prognostic-assessment-of-disease-progression-in-patients-with-gastric-and-esophageal-tumors
#30
JOURNAL ARTICLE
Daniel Vogele, Teresa Mueller, Daniel Wolf, Stephanie Otto, Sabitha Manoj, Michael Goetz, Thomas J Ettrich, Meinrad Beer
PURPOSE: Sarcopenia is considered a negative prognostic factor in patients with malignant tumors. Among other diagnostic options, computed tomography (CT), which is repeatedly performed on tumor patients, can be of further benefit. The present study aims to establish a framework for classifying the impact of sarcopenia on the prognosis of patients diagnosed with esophageal or gastric cancer. Additionally, it explores the significance of CT radiomics in both diagnostic and prognostic methodologies...
January 16, 2024: Diagnostics
https://read.qxmd.com/read/38241192/a-state-of-the-science-review-of-alcoholic-beverages-and-polycyclic-aromatic-hydrocarbons
#31
REVIEW
Liam King, Rebekah Aplin, Chris Gill, Timothy Naimi
BACKGROUND: The association between alcohol and certain cancers is well established, yet beyond ethanol and its metabolite acetaldehyde, little is known about the presence of other carcinogenic compounds in alcoholic beverages, including polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (a Group I carcinogen). OBJECTIVES: We summarized the published literature on PAH levels in alcoholic beverages to identify potential gaps in knowledge to inform future research...
January 2024: Environmental Health Perspectives
https://read.qxmd.com/read/38234703/recommendations-of-apex-health-bodies-remain-localized-not-in-conformity-with-international-implementation-policy-for-urological-disorders
#32
REVIEW
Suresh Kumar Goyal, Renu Bansal, Vikas Gupta, Cherry Bansal, Parveen Bansal
In developing/underdeveloped countries there is still a great burden of adverse drug reaction (ADR), morbidity and mortality because of poor regulations and implementation of preventive measures. These countries try to copy/follow guidelines from international bodies like American Urology Association (AUA), European Association of Urology (EAU), AGS, UMC and WHO irrespective of their country of origin and success in implementation. Although recommendations of these organizations are obligatory, yet these are taken as the gold standard for good clinical practices...
January 2024: Lancet Reg Health Southeast Asia
https://read.qxmd.com/read/38229436/polypharmacy-potentially-inappropriate-medication-and-dysphagia-in-older-inpatients-a-multi-center-cohort-study
#33
JOURNAL ARTICLE
Shintaro Togashi, Hironori Ohinata, Taiji Noguchi, Hidetaka Wakabayashi, Mariko Nakamichi, Akio Shimizu, Shinta Nishioka, Ryo Momosaki
BACKGROUND: Although the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged ≥65 years with dysphagia. METHODS: In this 19-center cohort study, we registered 467 inpatients aged ≥65 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores ≤8 between November 2019 and March 2021...
January 17, 2024: Annals of geriatric medicine and research
https://read.qxmd.com/read/38205194/prevalence-and-determinants-of-potentially-inappropriate-medications-in-elderly-inpatients-in-thailand-a-retrospective-observational-study-based-on-the-2019-beers-criteria
#34
JOURNAL ARTICLE
Tatta Sriboonruang, Sirichai Chusiri, Jiraphan Ritsamdang
BACKGROUND: The prevalence of potentially inappropriate medications (PIMs), including NSAIDs, first-generation antihistamines, tricyclic antidepressants (TCAs), and benzodiazepines among elderly inpatients in Thailand, based on the 2019 Beers criteria, is insufficiently investigated. METHODS: This study retrospectively examined 300 elderly patients in a Thai tertiary hospital, assessing four PIM classes based on the 2019 Beers criteria and exploring factors and variations in PIM prescription patterns across different phases of hospitalisation...
2024: Journal of Pharmaceutical Policy and Practice
https://read.qxmd.com/read/38183404/performance-of-potentially-inappropriate-medications-assessment-tools-in-older-indian-patients-with-cancer
#35
JOURNAL ARTICLE
Sharath Kumar, Renita Castelino, Abhijith Rao, Shreya Gattani, Anita Kumar, Anupa Pillai, Arshiya Sehgal, Pallavi Rane, Anant Ramaswamy, Ratan Dhekale, Jyoti Krishnamurthy, Shripad Banavali, Rajendra Badwe, Kumar Prabhash, Vanita Noronha, Vikram Gota
BACKGROUND: Polypharmacy and potentially inappropriate medication (PIM) use are common problems in older adults. Safe prescription practices are a necessity. The tools employed for the identification of PIM sometimes do not concur with each other. METHODS: A retrospective analysis of patients ≥60 years who visited the Geriatric Oncology Clinic of the Tata Memorial Hospital, Mumbai, India from 2018 to 2021 was performed. Beer's-2015, STOPP/START criteria v2, PRISCUS-2010, Fit fOR The Aged (FORTA)-2018, and the EU(7)-PIM list-2015 were the tools used to assess PIM...
January 6, 2024: Cancer Medicine
https://read.qxmd.com/read/38158855/medications-and-cognitive-risk-in-aboriginal-primary-care-a-cross-sectional-study
#36
JOURNAL ARTICLE
Marycarol Holdaway, Zoë Hyde, Jo-Anne Hughson, Roslyn Malay, Andrew Stafford, Kate Fulford, Kylie Radford, Leon Flicker, Kate Smith, Dimity Pond, Sarah Russell, David Atkinson, Irene Blackberry, Dina LoGiudice
BACKGROUND: Aboriginal and Torres Strait Islander people are ageing with high rates of comorbidity, yet little is known about suboptimal prescribing in this population. AIM: The prevalence of potentially suboptimal prescribing and associated risk factors were investigated among older patients attending primary care through Aboriginal Community Controlled Health Services (ACCHSs). METHODS: Medical records of 420 systematically selected patients aged ≥50 years attending urban, rural and remote health services were audited...
December 30, 2023: Internal Medicine Journal
https://read.qxmd.com/read/38124261/mapping-potentially-inappropriate-medications-in-older-adults-using-the-anatomical-therapeutic-chemical-atc-classification-system
#37
JOURNAL ARTICLE
Asinamai Ndai, Julie Al Bahou, Earl Morris, Hsin-Min Wang, Zach Marcum, Anna Hung, Nicole Brandt, Michael A Steinman, Scott Martin Vouri
BACKGROUND: Potentially inappropriate medications (PIMs) in older adults are medications in which risks often outweigh benefits and are suggested to be avoided. Worldwide, many distinct guidelines and tools classify PIMs in older adults. Collating these guidelines and tools, mapping them to a medication classification system, and creating a crosswalk will enhance the utility of PIM guidance for research and clinical practice. METHODS: We used the Anatomical Therapeutic Chemical (ATC) Classification System, a hierarchical classification system, to map PIMs from eight distinct guidelines and tools (2019 Beers Criteria, Screening Tool for Older Person's Appropriate Prescriptions [STOPP], STOPP-Japan, German PRISCUS, European Union-7 Potentially Inappropriate Medication [PIM] list, Centers for Medicare & Medicaid Services [CMS] High-Risk Medication, Anticholinergic Burden Scale, and Drug Burden Index)...
January 2024: Journal of the American Geriatrics Society
https://read.qxmd.com/read/38066430/potentially-inappropriate-medications-among-older-patients-with-parkinson-s-disease-a-cross-sectional-analysis-of-a-national-health-insurance-database-in-china
#38
JOURNAL ARTICLE
Mengyuan Fu, Can Li, Zinan Zhao, Kexin Ling, Zhiwen Gong, Huangqianyu Li, Ting Li, Jianchun Li, Weihang Cao, Xin Hu, Luwen Shi, Pengfei Jin, Xiaodong Guan
BACKGROUND: With the rapid aging trend of China's population, the issue of drug rational use in older adults has become more and more prominent. Parkinson's disease (PD) is the one of the most common age-related neurodegenerative disorders. Pharmaceutical treatment plays a cardinal role in alleviating motor and non-motor symptoms to improve the quality of life of patients with PD. Patients with PD have complex medical needs yet little is known about the use of potentially inappropriate medications (PIM) among them in China...
December 8, 2023: BMC Geriatrics
https://read.qxmd.com/read/38063911/-the-forta-fit-for-the-aged-list
#39
REVIEW
Farhad Pazan, Martin Wehling
BACKGROUND: Multimorbidity and the resulting polypharmacy are widespread in the very old and the evidence on the efficacy and safety of drugs in older people is sparse. Driven by guidelines, this often leads to inappropriate prescribing and drug-related problems. MATERIAL AND METHODS: To improve this, numerous listing approaches were developed as tools to optimize medication. These approaches can be divided into drug-oriented listing approaches (DOLA), such as the Beers Criteria®, a list of potentially inappropriate medications for older people or patient-in-focus listing approaches (PILA), such as the Fit fOR The Aged (FORTA) list...
December 8, 2023: Inn Med (Heidelb)
https://read.qxmd.com/read/38037179/potentially-inappropriate-medicine-use-and-predicting-risk-factors-in-hospitalized-older-adult-patients-findings-of-a-prospective-observational-study-from-ethiopia
#40
JOURNAL ARTICLE
Behailu Terefe Tesfaye, Dula Dessalegn Bosho, Gashahun Mekonnen Dissassa, Mikiyas Gashaw Tesfaye, Mengist Awoke Yizengaw
BACKGROUND: Older patients are fragile and more susceptible to medication-related problems requiring a strict assessment of their medicine list. The present study was conducted with the intention to assess the quality use of medicines in older adult patients by detecting potentially inappropriate medicine use and its predictive risk factors. METHODS: This prospective cross-sectional study involved 162 older medical patients admitted to Jimma Medical Center. A data abstraction format is employed to capture relevant information...
November 30, 2023: Journal of Pharmaceutical Policy and Practice
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