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https://www.readbyqxmd.com/read/29029963/genetic-risk-factors-in-finnish-patients-with-parkinson-s-disease
#1
Susanna Ylönen, Ari Siitonen, Michael A Nalls, Pauli Ylikotila, Jaana Autere, Johanna Eerola-Rautio, Raphael Gibbs, Mikko Hiltunen, Pentti J Tienari, Hilkka Soininen, Andrew B Singleton, Kari Majamaa
INTRODUCTION: Variation contributing to the risk of Parkinson's disease (PD) has been identified in several genes and at several loci including GBA, SMPD1, LRRK2, POLG1, CHCHD10 and MAPT, but the frequencies of risk variants seem to vary according to ethnic background. Our aim was to analyze how variation in these genes contributes to PD in the Finnish population. METHODS: The subjects consisted of 527 Finnish patients with early-onset PD, 325 patients with late-onset PD and 403 population controls...
September 29, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28987777/palestinian-arab-ethnicity-is-associated-with-an-adverse-metabolic-phenotype
#2
Ram Weiss, Hisham Nassar, Ronit Sinnreich, Wiessam Abu-Ahmad, James Otvos, Jeremy D Kark
Urban-dwelling Palestinians have been shown to have higher cardiovascular morbidity and mortality and prevalence of diabetes than urban Israelis. Inflammation is implicated in the etiology of these conditions. We hypothesized that increased inflammatory activation, manifested as increased GlycA, a novel biomarker of global inflammation, would be evident in Palestinians. We compared GlycA concentrations between Palestinians and Israelis and assessed the associations of GlycA with anthropometric, health behavioral and clinical variables in a sample of 1674 Palestinians and Israelis aged 25-74, residing in Jerusalem...
October 4, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28982344/retraction-ankylosing-spondylitis-among-familial-mediterranean-fever-patients
#3
(no author information available yet)
This paper is under revision and has not been accepted yet.
October 3, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28976926/environmental-influences-on-physical-activity-among-rural-adults-in-montana-united-states-views-from-built-environment-audits-resident-focus-groups-and-key-informant-interviews
#4
Brian K Lo, Emily H Morgan, Sara C Folta, Meredith L Graham, Lynn C Paul, Miriam E Nelson, Nicolette V Jew, Laurel F Moffat, Rebecca A Seguin
Rural populations in the United States have lower physical activity levels and are at a higher risk of being overweight and suffering from obesity than their urban counterparts. This paper aimed to understand the environmental factors that influence physical activity among rural adults in Montana. Eight built environment audits, 15 resident focus groups, and 24 key informant interviews were conducted between August and December 2014. Themes were triangulated and summarized into five categories of environmental factors: built, social, organizational, policy, and natural environments...
October 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28969362/author-s-reply-impact-on-health-and-healthcare-costs-if-monounsaturated-fatty-acids-were-substituted-for-conventional-dietary-oils-in-the-united-states
#5
Mohammad M H Abdullah, Stephanie Jew, Peter J H Jones
No abstract text is available yet for this article.
August 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28951006/genetic-portrait-of-jewish-populations-based-on-three-sets-of-x-chromosome-markers-indels-alu-insertions-and-strs
#6
J F Ferragut, K Bentayebi, R Pereira, J A Castro, A Amorim, C Ramon, A Picornell
Population genetic data for 53 X-chromosome markers (32 X-indels, 9 X-Alu insertions and 12 X-STRs) are reported for five populations with Jewish ancestry (Sephardim, North African Jews, Middle Eastern Jews, Ashkenazim, and Chuetas) and Majorca, as the host population of Chuetas. Genetic distances between these populations demonstrated significant differences, except between Sephardic and North African Jews, with the Chuetas as the most differentiated group, in accordance with the particular demographic history of this population...
September 18, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28948342/pediatric-mycosis-fungoides-a-study-of-the-human-leukocyte-antigen-system-among-israeli-jewish-patients
#7
Ofer Reiter, Dan Ben Amitai, Iris Amitay-Laish, Moshe Israeli, Lev Pavlovsky, Emmilia Hodak
Pediatric mycosis fungoides (MF) is a rare disease characterized by over-representation of atypical clinical variants, with a different prognosis from adult MF. Several human leukocyte antigen (HLA) alleles have been associated with MF in certain adult populations, including Israeli Jews. However, HLA data on pediatric MF as a group are lacking. To evaluate the possible association of the HLA system with pediatric MF, 59 Israeli Jewish patients diagnosed with MF at age ≤ 18 years underwent high- and intermediate-resolution genotyping for HLA class I (HLA-A*, HLA-B*) and class II (HLA-DRB1*, DQB1*) loci...
September 25, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28942756/association-between-schizophrenia-and-an-autoimmune-bullous-skin-disease-pemphigus-a-population-based-large-scale-study
#8
K Kridin, S Zelber-Sagi, D Comaneshter, A D Cohen
AIMS: Immunological hypotheses have become increasingly prominent suggesting that autoimmunity may be involved in the pathogenesis of schizophrenia. Schizophrenia was found to be associated with a wide range of autoimmune diseases. However, the association between pemphigus and schizophrenia has not been established yet. We aimed to estimate the association between pemphigus and schizophrenia using a large-scale real-life computerised database. METHODS: This study was conducted as a cross-sectional study utilising the database of Clalit Health Services...
September 25, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28910809/ingeborg-syllm-rapoport-1912-2017-an-exemplary-life-for-children-and-paediatrics
#9
Hannes Sallmon, Roland R Wauer, Charles Christoph Roehr
Ingeborg Syllm-Rapoport, the first Chair in neonatology in Europe, passed away on March 23. Her biography illustrates how medical and scientific work has been influenced by social, ideological, and economic frames and boundaries in the 20th century. Regarded as a "Half-Jew" by the Nazi racist laws, she was denied her medical doctorate. She went to the USA, where she trained in paediatrics and met her husband, the biochemist Samuel Mitja Rapoport. During the "McCarthy Era" both were persecuted as communists...
September 15, 2017: Neonatology
https://www.readbyqxmd.com/read/28910803/consanguinity-rates-predict-long-runs-of-homozygosity-in-jewish-populations
#10
Jonathan T L Kang, Amy Goldberg, Michael D Edge, Doron M Behar, Noah A Rosenberg
OBJECTIVES: Recent studies have highlighted the potential of analyses of genomic sharing to produce insight into the demographic processes affecting human populations. We study runs of homozygosity (ROH) in 18 Jewish populations, examining these groups in relation to 123 non-Jewish populations sampled worldwide. METHODS: By sorting ROH into 3 length classes (short, intermediate, and long), we evaluate the impact of demographic processes on genomic patterns in Jewish populations...
September 15, 2017: Human Heredity
https://www.readbyqxmd.com/read/28903797/prevalence-of-anti-hepatitis-b-surface-antibodies-among-children-and-adolescents-vaccinated-in-infancy-and-effect-of-booster-dose-administered-within-a-pilot-study
#11
R Bassal, M P Markovich, M Weil, E Shinar, Y Carmeli, M Dan, D Sofer, E Mendelson, D Cohen, T Shohat
We determined the prevalence of anti-hepatitis B surface antibodies (anti-HBs) among children and adolescents vaccinated for hepatitis B virus in infancy as part of the routine vaccination programme. A representative serum sample of the Israeli population age 0-19 was tested. In a separate pilot study, a booster dose of hepatitis B vaccine was administered to 31 candidates for national service, who were fully vaccinated in infancy and tested negative for hepatitis B surface antibodies at age 17-19 years and anti-HBs antibodies were assessed 8 weeks later...
October 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28903662/looking-backward-to-move-forward-effects-of-acknowledgment-of-victimhood-on-readiness-to-compromise-for-peace-in-the-protracted-israeli-palestinian-conflict
#12
Boaz Hameiri, Arie Nadler
Two large-scale surveys conducted in Israel (Study 1A) and the Palestinian Authority (Study 1B) show that the belief by group members that people in the "enemy" group acknowledge their victimhood (i.e., Holocaust and Nakba for Jews and Palestinians, respectively) is associated with Israeli-Jews' readiness to accept responsibility for Palestinian sufferings and offer apologies. For Palestinians, this belief is linked to a perceived higher likelihood of a reconciled future with Israelis. Three field experiments demonstrate that a manipulated high level of acknowledgment of Jewish victimhood by Palestinians (Studies 2 and 4) and of Palestinian victimhood by Israeli-Jews (Study 3) caused greater readiness to make concessions for the sake of peace on divisive issues (e...
April 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28900478/esophageal-cancer-in-israel-has-unique-clinico-pathological-features-a-retrospective-study
#13
Michal Sarfaty, Esty Lankry, Assaf Moore, Noga Kurman, Ofer Purim, Yulia Kundel, Irit Ben-Aharon, Gali Perl, Olga Ulitsky, Noa Gordon, Aaron Sulkes, Nikolai Menasherov, Hanoch Kashtan, Baruch Brenner
Introduction: Data regarding esophageal cancer (EC) in Israel are limited. The aim of this study was hence to characterize this entity in the Israeli population and to compare it to the literature. Patients/Methods: This is a retrospective study of all consecutive EC patients treated at our institution between 1997-2013. Data were retrieved from patients' medical files. Results: Two hundred patients were included. The median age at diagnosis was 70.5 years; 63.5% were males; 63% were Ashkenazi Jews, 29% were Sephardic Jews, and 0...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28899110/unpleasant-business-rat-jew-payment-and-covenant-in-freud-s-rat-man
#14
Annie Atura
Freud's repression of Judaism and its cultural markers from the published "Rat Man" case history has been noted but never satisfactorily explained. This elision can be interpreted using Freud's suggestion that the paradigmatic "rat" represents (among other things) a circumcised penis marking an intergenerational, covenantal exchange. When read against the case study as originally published, Freud's process notes for the Rat Man's treatment (the only set of such notes on a published case that Freud didn't destroy) suggest that Freud chose to sanitize the published version of explicitly Jewish content, thus repeating a pattern of absence as a marker of debt...
April 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28855964/youth-in-the-midst-of-escalated-political-violence-sense-of-coherence-and-hope-among-jewish-and-bedouin-arab-adolescents
#15
Sarah Abu-Kaf, Orna Braun-Lewensohn, Tehila Kalagy
BACKGROUND: During stressful events, individuals (particularly adolescents) from minority groups are often more vulnerable to distress. This claim will be examined in terms of coping resources and stress reactions to escalated political violence. This study aimed to compare coping resources and stress reactions among adolescents from two ethnic groups in southern Israel-Jews and Bedouin Arabs-during a period of escalated political violence (November 2012). The Bedouin Arab group is the ethnic minority of the sample and thus may be more at risk compared to the Jewish group...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28848105/two-ethnic-clusters-with-huntington-disease-in-israel-the-case-of-mountain-jews-and-karaites
#16
Jennifer Zitser, Avner Thaler, Noit Inbar, Alona Gad, Achinoam Faust-Socher, Diana Paleacu, Marieta Anca-Herschkovitch, Yakov Balash, Hertzel Shabtai, Elissa L Ash, Ludmila Merkin, Yael Manor, Meir Kestenbaum, Aya Bar David, Chava Peretz, Tova Naiman, Anat Bar-Shira, Avi Orr-Urtreger, Nira Dangoor, Nir Giladi, Tanya Gurevich
BACKGROUND: Worldwide prevalence estimates of Huntington disease (HD) vary widely, with no reliable information regarding the Jewish population in Israel. METHODS: This specialized tertiary single-center cross-sectional study assessed clinical, cognitive, and demographic characteristics of 84 HD patients who were treated at the Movement Disorder Unit of the Tel Aviv Medical Center, Israel. RESULTS: Our cohort was composed of one-third Ashkenazi Jews, 27% Mountain Jews (Caucasus Jews), 18% Sephardi Jews, and 21% Karaites, with both Mountain Jews and Karaites over-represented compared to their relevant proportion in the population of the state of Israel, which is less than 1%...
August 25, 2017: Neuro-degenerative Diseases
https://www.readbyqxmd.com/read/28837003/a-national-strategic-plan-for-reducing-the-burden-of-sexually-transmitted-infections-in-israel-by-the-year-2025
#17
Daniel Chemtob, Dan Gandacu, Zohar Mor, Itamar Grotto, Emilia Anis, Elliot Rosenberg
BACKGROUND: There is on ongoing debate in the literature regarding the real burden of STIs (sexually transmitted infections) in Western countries and the proper strategies needed to estimate and to prevent them. Our purpose is to present an evidence-based national strategic plan for STI prevention in Israel through assessing the current burden of illness, leading international preventive strategies, and practical policymaking experience. METHODS: Epidemiologic and health policy data on STIs were analyzed from various sources: a) systematic national surveillance data for the years 2002-2014; b) the international scientific literature (published between 2002-16; keywords: Sexually Transmitted Diseases (STD) (or STI) AND prevention AND intervention AND gonorrhea OR chlamydia OR syphilis; c) internal Ministry of Health (MOH) analyses and reports, and d) expert opinion...
April 19, 2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/28829689/theoretical-and-experimental-investigations-of-mercury-adsorption-on-hematite-surfaces
#18
Ji-Eun Jung, Simona Liguori, Adam D Jew, Gordon E Brown, Jennifer Wilcox
One of the biggest environmental concerns caused by coal-fired power plants is the emission of mercury (Hg), which is toxic metal. To control the emission of Hg from coal-derived flue gas, it is important to understand the behavior, speciation of Hg as well as the interaction between Hg and solid materials in the flue gas stream. In this study, atomic-scale theoretical investigations using density functional theory (DFT) were carried out in conjunction with lab-scale experimental studies to investigate the adsorption behavior of Hg on hematite (?-Fe2O3)...
August 22, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28828701/inherited-predisposition-to-breast-and-ovarian-cancer-in-non-jewish-populations-in-israel
#19
Jamal Zidan, Alicia Y Zhou, Jeroen van den Akker, Yael Laitman, Hagit Schayek, Julia Schnaider, Eitan Friedman
PURPOSE: The contribution of genetic factors to cancer in non-Jewish populations in Israel is understudied. Yet the early, mostly premenopausal age at breast cancer diagnosis is suggestive of an inherited predisposition. METHODS: High-risk cancer cases of non-Jewish origin who were counseled at the Oncogenetics unit, Sheba Medical Center and the oncology institute at the Ziv medical center from January 1, 2000 to December 31 2016 were eligible. DNA extracted from leukocytes was subjected to massive parallel, next-generation sequencing using the Color Genomics platform...
August 21, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28812022/histopathologic-differences-between-jewish-and-arab-population-in-israel-at-first-time-presentation-with-bladder-cancer
#20
Ofir Avitan, Zaher Bahouth, Sarel Halachmi, Sagi Shprits, Ismail Masarwa, Edmond Sabo, Boaz Moskovitz, Ofer Nativ
BACKGROUND: Pathology of urothelial carcinoma may vary in different populations at diagnosis. Our aim was to evaluate the histopathologic differences between Jewish and Arab patients in Israel at first diagnosis of urothelial cancer. PATIENTS AND METHODS: We retrospectively collected data of all patients with confirmed urothelial cancer, treated at our department between January 2010 and January 2015. We examined the distribution of the histopathologic data among the studied populations...
2017: BioMed Research International
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