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Restenosis

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https://www.readbyqxmd.com/read/29349698/third-generation-dual-source-ct-enables-accurate-diagnosis-of-coronary-restenosis-in-all-size-stents-with-low-radiation-dose-and-preserved-image-quality
#1
Yuehua Li, Mengmeng Yu, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVES: To investigate the diagnostic performance of low dose stent imaging in patients with large (≥ 3 mm) and small (< 3 mm) calibre stents by third-generation dual-source CT. METHODS: Symptomatic patients suspected of having in-stent restenosis (ISR) were prospectively enrolled. Coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA) were performed within 1 month for correlation. Binary ISR was defined as an in-stent neointimal proliferation with diameter stenosis ≥ 50%...
January 18, 2018: European Radiology
https://www.readbyqxmd.com/read/29349384/acute-hemifacial-ischemia-as-a-late-complication-of-carotid-stenting
#2
Maurizio Domanin, Maurizio Isalberti, Silvia Romagnoli, Antonio Rolli, Simona Sommaruga
Concerns about carotid artery stenting (CAS) center primarily on procedural complications like acute occlusion, stroke, and long-term intrastent restenosis. External carotid artery (ECA) thrombosis is observed during CAS follow-up, but it often remains asymptomatic or, at worst, results in jaw claudication. We report here a case of late occlusion of the ECA after CAS with symptoms of acute homolateral facial ischemia as well as pain, cyanosis, tongue numbness, and skin coldness. The patient was submitted to local thrombolysis and balloon angioplasty with regression of symptoms after recanalization...
June 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29340719/treatment-with-48-mm-everolimus-eluting-stents-procedural-safety-and-12-month-patient-outcome
#3
C K Tan, Z L Tin, M K M Arshad, J K K Loh, F H Jafary, H H Ho, P J L Ong, T Watson
BACKGROUND: Lesion length is a major predictor of adverse outcomes after percutaneous coronary intervention. Long lesions often require multiple stents with variable overlap, which increases the probability of geographical miss and the incidence of mechanical complications, such as side-branch occlusion, restenosis, and stent thrombosis. These pitfalls may be avoided by use of an ultra-long device. METHODS: We retrospectively assessed the performance of the 48-mm Xience Xpedition everolimus-eluting stent (EES) at our institution...
January 16, 2018: Herz
https://www.readbyqxmd.com/read/29338896/novel-bioabsorbable-polymer-and-polymer-free-metallic-drug-eluting-stents
#4
REVIEW
Jason Nogic, Liam M McCormick, Rohin Francis, Nitesh Nerlekar, Catherine Jaworski, Nick E J West, Adam J Brown
The introduction of drug-eluting stents (DES) significantly reduced angiographic restenosis and the clinical need for revascularization following percutaneous coronary intervention. However, concerns remain regarding the long-term safety and efficacy of DES. The use of durable polymers for drug elution that have limited biocompatibility is thought to contribute toward DES failure, by promoting an adverse local inflammatory response and vascular toxicity. Biodegradable polymer and polymer-free metallic stents represent two novel technological solutions to this challenging clinical problem...
January 12, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29338303/evaluation-of-preprocedural-laboratory-parameters-as-predictors-of-drug-eluting-stent-restenosis-in-coronary-chronic-total-occlusion-lesions
#5
Chenguang Li, Yi Shen, Rende Xu, Yuxiang Dai, Shufu Chang, Hao Lu, Zhaohui Dong, Jianxin Deng, Juying Qian, Junbo Ge
This retrospective, single-center study assessed the prognostic value of several emerging inflammatory markers as predictors of in-stent restenosis (ISR) after drug-eluting stent implantation for coronary chronic total occlusion (CTO) lesions. Consecutive patients (n = 416) who underwent successful percutaneous coronary intervention (PCI) for documented CTO lesions and with follow-up angiography were enrolled. Preprocedural high-sensitivity C-reactive protein (hsCRP), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and red cell distribution width (RDW) were analyzed...
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29336771/surgical-and-endovascular-management-of-patients-with-chronic-mesenteric-ischemia-a-single-center-experience
#6
Panagiotis Paliogiannis, Giorgio C Ginesu, Alessandro Fancellu, Aldo Pischedda, Mario Maiore, Eleonora Maiore, Antonio Pinna, Michele Barmina, Alberto Porcu
Chronic mesenteric ischemia is a rare intestinal disorder, with a potential evolution toward intestinal infraction. The choice of the appropriate treatment is currently the most crucial issue in the management of patients with chronic mesenteric ischemia. We describe our experience with 16 cases, and we discuss the current diagnostic and therapeutic approaches. A retrospective review of the clinical records was performed, and demographic, clinical, therapeutic, and prognostic data were collected. Six patients were females (37%), and the mean age was 62 years...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29332922/role-of-gene-polymorphisms-haplotypes-and-plasma-level-of-tgf-%C3%AE-1-in-susceptibility-to-in-stent-restenosis-following-coronary-implantation-of-bare-metal-stent-in-chinese-han-patients
#7
Hai-Jian Chen, Ni Mo, Yan-Feng Zhang, Guo-Zhu Su, Han-Dong Wu, Fang Pei
Transforming growth factor (TGF)-β1 has been implicated in the pathogenesis of restenosis. However, the role of TGF-β1 polymorphisms in development of in-stent restenosis (ISR) after coronary bare metal stent (BMS) implantation in Chinese Han population has not been reported to date. The aim of this study was to explore the association between TGF-β1 gene polymorphisms (-509C/T and 869T/C) and its plasma level in Chinese Han patients with BMS-ISR.We investigated 419 patients after successful coronary stent placement...
January 15, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29332914/long-term-clinical-outcomes-after-treatment-with-excimer-laser-coronary-atherectomy-for-in-stent-restenosis-of-drug-eluting-stent
#8
Eiji Ichimoto, Tadayuki Kadohira, Takashi Nakayama, Joseph De Gregorio
Excimer laser coronary atherectomy (ELCA) has been used for the treatment of complex percutaneous coronary intervention (PCI) such as in-stent restenosis (ISR). However, little information was provided about the clinical outcomes after treatment with ELCA for ISR of drug-eluting stents (DES). This study aimed to investigate the long-term clinical outcomes after PCI with ELCA for ISR of DES.A total of 81 consecutive patients with 87 lesions who underwent PCI for ISR of DES were included. Patients were classified into a PCI with ELCA group (23 patients with 24 lesions) and a PCI without ELCA group (58 patients with 63 lesions)...
January 15, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29332315/comparison-of-treatment-strategies-for-femoro-popliteal-disease-a-network-meta-analysis
#9
Edward Koifman, Michael J Lipinski, Kyle Buchanan, Won Yu Kang, Ricardo O Escarcega, Ron Waksman, Nelson L Bernardo
OBJECTIVES: We sought to compare treatment strategies in a Bayesian network meta-analysis of randomized controlled trials. BACKGROUND: Peripheral artery disease (PAD) is a prevalent morbidity that is treated with various strategies. METHODS: We performed a MEDLINE search for randomized studies comparing at least 2 treatment strategies, including bypass surgery, percutaneous transluminal angioplasty (PTA) balloons, stents, covered stents, drug-eluting stents (DES), and drug-coated balloons (DCB), in patients with native femoro-popliteal disease...
January 14, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29331436/jetstream-atherectomy-system-treatment-of-femoropopliteal-arteries-results-of-the-post-market-jet-registry
#10
William A Gray, Lawrence A Garcia, Ali Amin, Nicolas W Shammas
OBJECTIVES: To report on procedural, safety, and effectiveness outcomes of real-world practice with the Jetstream rotational atherectomy system for treatment of femoropopliteal artery lesions. BACKGROUND: Safety and effectiveness of treatment with the Jetstream device has been demonstrated in clinical trials, but outcomes during real-world clinical practice have yet to be examined. METHODS: 241 patients (66% male, mean age 67years, 41% diabetes; Rutherford 1-3) with de novo or restenotic (non-stent) femoropopliteal lesions ≥4cm in length were recruited...
December 27, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29331343/irradiation-stents-vs-conventional-metal-stents-for-unresectable-malignant-biliary-obstruction-a-multicentre-trial
#11
Hai-Dong Zhu, Jin-He Guo, Ming Huang, Jian-Song Ji, Hao Xu, Jian Lu, Hai-Liang Li, Wen-Hui Wang, Yu-Liang Li, Cai-Fang Ni, Hai-Bin Shi, En-Hua Xiao, Wei-Fu Lv, Jun-Hui Sun, Ke Xu, Guo-Hong Han, Lin-An Du, Wei-Xin Ren, Mao-Quan Li, Ai-Wu Mao, Hua Xiang, Kai-Xian Zhang, Jie Min, Guang-Yu Zhu, Chang Su, Li Chen, Gao-Jun Teng
BACKGROUND & AIMS: Placement of an irradiation stent has been demonstrated to offer longer patency and survival when compared to an uncovered SEMS in patients with unresectable malignant biliary obstruction (MBO). We aim to further assess the efficacy of an irradiation stent compared to an uncovered SEMS in those patients. METHODS: We performed a randomized, open-label trial of participants with unresectable MBO at 20 centers in China. A total of 328 participants were parallelly allocated into the irradiation stent group (ISG) or the uncovered SEMS group (USG)...
January 10, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29327045/serial-in-office-intralesional-steroid-injections-in-airway-stenosis
#12
Caitlin Bertelsen, Hagit Shoffel-Havakuk, Karla O'Dell, Michael M Johns, Lindsay S Reder
Importance: Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis (SGS/PTS). Its major limitation is restenosis requiring repeated surgery. Intralesional steroid injection (ISI) is a promising adjunctive treatment aimed at prolonging the effects of dilation. Objective: To evaluate the association of serial in-office ISI after endoscopic dilation with surgery-free interval (SFI) in adults with SGS/PTS. Design, Setting, and Participants: A retrospective study of adults with SGS/PTS who underwent at least 2 consecutive in-office ISI at the University of Southern California, Keck School of Medicine, over a 3-year period was conducted...
January 11, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29326163/lim-and-cysteine-rich-domains-1-is-required-for-thrombin-induced-smooth-muscle-cell-proliferation-and-promotes-atherogenesis
#13
Jagadeesh Janjanam, Baolin Zhang, Arul M Mani, Nikhlesh K Singh, James G Traylor, A Wayne Orr, Gadiparthi N Rao
Restenosis arises after vascular injury and is characterized by arterial wall thickening and decreased arterial lumen space. Vascular injury induces the production of thrombin, which in addition to its role in blood clotting, acts as a mitogenic and chemotactic factor. In exploring the molecular mechanisms underlying restenosis, here we identified LIM and cysteine-rich domains 1 (LMCD1) as a gene highly responsive to thrombin in human aortic smooth muscle cells (HASMCs). Of note, LMCD1 depletion inhibited proliferation of human but not murine vascular smooth muscle cells...
January 11, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29325950/a-novel-technique-for-cervical-laminoplasty-fusion-clpf-simultaneously-enhancing-stabilization-and-decompression-in-various-cervical-myelopathies-a-technical-note-and-outcomes
#14
Il Sup Kim, Jae Taek Hong, Jung Jae Lee, Jong Bum Lee, Chul Bum Cho, Seung Ho Yang, Jae Hoon Sung
PURPOSE: Cervical laminectomy has two major disadvantages: post-laminectomy adhesion of dural membrane and the lack of a fusion bed. The objective of this study was to determine whether simultaneous laminoplasty with fusion (CLPF) might overcome these unwanted outcomes. METHODS: Cases of CLPF for treating various cervical myelopathy with instability who were followed up for at least 12 months were enrolled. Preoperative and postoperative Neck Disability Index (NDI), Japanese Orthopedic Association (JOA) scores before and after surgeries, recovery rates (RRs), C2-7 lordosis, and fusion success rates were evaluated...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29325041/spontaneous-massive-hemothorax-presenting-as-a-late-complication-of-stent-implantation-in-a-patient-with-pulmonary-vein-stenosis-following-radiofrequency-ablation-for-atrial-fibrillation
#15
Andres Obeso, Amara Tilve, Alejandro Jimenez, Johannes Bonatti
Catheter ablation for symptomatic and drug-resistant atrial fibrillation is considered as the main acquired cause of pulmonary vein stenosis in adults. Controversy currently exists about the optimal treatment approach of this entity. Stenting seems to achieve lower vessel restenosis rates than isolated balloon angioplasty. However, these techniques are not exempt from complications. We present a case of spontaneous massive haemothorax presenting as a late complication of stent implantation in a patient with pulmonary vein stenosis...
January 6, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29316284/a-propensity-score-matched-comparison-of-biodegradable-polymer-versus-second-generation-durable-polymer-drug-eluting-stents-in-a-real-world-population
#16
Ying Jiao Zhao, Monica Teng, Ai Leng Khoo, Rajiv Ananthakrishna, Tiong Cheng Yeo, Boon Peng Lim, Joshua P Loh, Mark Y Chan
AIMS: The safety and efficacy of BP-DES compared to second-generation DP-DES remain unclear in the real-world setting. We compared the clinical outcomes of biodegradable polymer drug-eluting stents (BP-DES) with second-generation durable polymer drug-eluting stents (DP-DES) in an all-comer percutaneous coronary intervention (PCI) registry. METHODS/RESULTS: The study included a cohort of 1,065 patients treated with either BP-DES or DP-DES from January 2009 through October 2015...
January 8, 2018: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/29314563/subadventitial-stenting-around-occluded-stents-a-bailout-technique-to-recanalize-in-stent-chronic-total-occlusions
#17
Lorenzo Azzalini, Aris Karatasakis, James C Spratt, Péter Tajti, Robert F Riley, Luiz F Ybarra, Stefan P Schumacher, Susanna Benincasa, Barbara Bellini, Luciano Candilio, Satoru Mitomo, Peter Henriksen, Francisco Hidalgo, Leo Timmers, Adriaan O Kraaijeveld, Pierfrancesco Agostoni, James Roy, David R Ramsay, James C Weaver, Paul Knaapen, Alexander Nap, Boris Starcevic, Soledad Ojeda, Manuel Pan, Khaldoon Alaswad, William L Lombardi, Mauro Carlino, Emmanouil S Brilakis, Antonio Colombo, Stéphane Rinfret, Kambis Mashayekhi
OBJECTIVES: To evaluate the outcomes of subadventitial stenting (SS) around occluded stents for recanalizing in-stent chronic total occlusions (IS-CTOs). BACKGROUND: There is little evidence on the outcomes of SS for IS-CTO. METHODS: We examined the outcomes of SS for IS-CTO PCI at 14 centers between July 2011 and June 2017, and compared them to historical controls recanalized using within-stent stenting (WSS). Target-vessel failure (TVF) on follow-up was the endpoint of this study, and was defined as a composite of cardiac death, target-vessel myocardial infarction, and target-vessel revascularization...
January 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29310895/commentary-on-a-propensity-matched-comparison-for-open-and-endovascular-treatment-of-post-carotid-endarterectomy-restenosis
#18
A Ross Naylor
No abstract text is available yet for this article.
January 5, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29305859/n-oleoylethanolamide-suppresses-intimal-hyperplasia-after-balloon-injury-in-rats-through-ampk-ppar%C3%AE-pathway
#19
Yun Zhao, Yijun Liu, Zuo Jing, Lu Peng, Peng Jin, Yangbin Lin, Yu Zhou, Lichao Yang, Jie Ren, Qiang Xie, Xin Jin
Vascular smooth muscle cell (VSMC) proliferation and migration are crucial events in the pathological course of restenosis after percutaneous coronary intervention (PCI). N-oleoylethanolamide (OEA) is a bioactive lipid amide released upon dietary fat digestion with many reported actions. However, the effect of OEA on restenosis after vascular injury remains unknown. Here, we investigated the effects of OEA on intimal hyperplasia after balloon injury in vivo, its effect on VSMC proliferation and migration induced by platelet-derived growth factor (PDGF) stimulation in vitro, and the underlying mechanism underlying these effects...
January 3, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29305846/the-value-of-serum-visfatin-in-predicting-in-stent-restenosis-of-drug-eluting-stents
#20
Xing-An Wu, Gang Xie, Xiu-Qi Li, Hui-Ting Wu, Xiang Wang
OBJECTIVE: This study aims to determine the association between serum visfatin level and in-stent restenosis (ISR) after percutaneous coronary intervention (PCI) using drug-eluting stents (DES). METHODS: A total of 460 patients with stable coronary heart disease who underwent DES placement were included. According to the results of coronary angiography 1year after PCI, 62 patients diagnosed as ISR were enrolled into the ISR group and 398 patients without ISR were recruited into the control group...
January 3, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
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