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https://www.readbyqxmd.com/read/28532066/design-and-characterization-of-a-novel-nickel-free-cobalt-base-alloy-for-intravascular-stents
#1
Qiang Wang, Yibin Ren, M Babar Shahzad, Wei Zhang, Xumeng Pan, Song Zhang, Dan Zhang
Co-Cr-W-Ni alloy (L605) with high tensile strength is used in coronary stents. The thickness of individual strut of the stent is reduced which can decrease the stent restenosis rate. However, about 10% Ni element content in L605 is found to cause allergic reactions and pulmonary embolism, similar to the traditional 316L stainless steel. In this study, a novel nickel-free cobalt-base alloy Co-20Cr-12Fe-18Mn-2Mo-4W-N (wt%) was designed and fabricated in order to efficiently avoid the potential hazards of Ni element...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28530624/-buccal-mucosa-graft-for-the-treatment-of-long-ureteral-stenosis-bibliographic-review
#2
Gema Del Pozo Jiménez, Ignacio Castillón-Vela, Joaquín Carballido Rodríguez
OBJECTIVE: To perform a literature review on the use of buccal mucosa graft (BMG) in the treatment of extensive ureteral stenosis, according to the criteria of Evidence Based Medicine. METHODS: Pubmed search of published studies with the following keywords: "ureteral stricture treatment", "buccal mucosa graft ureteral treatment" and "buccal mucosa graft ureteroplasty", without time limits, in English and Spanish; 12 articles were identified with a total of 48 cases (46 patients) of BMG use in ureteral repair...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28523446/in-vitro-quantification-of-luminal-denudation-after-crimping-and-balloon-dilatation-of-endothelialized-covered-stents
#3
Shigeo Ichihashi, Frederic Wolf, Thomas Schmitz-Rode, Kimihiko Kichikawa, Stefan Jockenhoevel, Petra Mela
PURPOSE: Covered stents have been demonstrated to reduce restenosis; however, the membrane's limited biocompatibility can still lead to thrombus formation. To obtain optimal surface hemocompatibility, endothelialization of the luminal surface has been proposed. However, the effect of delivery procedures, such as crimping and balloon dilatation, on the endothelial layer has not been quantified. This study investigated the impact of such procedures on endothelialized covered stents in vitro...
May 18, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28521970/corrigendum-to-the-role-of-c-jun-in-pdtc-sensitive-flow-dependent-restenosis-after-angioplasty-and-stenting-atherosclerosis-194-2-2007-364-371
#4
Melanie Murrell, Levon Khachigian, Michael R Ward
No abstract text is available yet for this article.
June 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28516211/early-endothelialization-associated-with-a-biolimus-a9-bioresorbable-polymer-stent-in-a-porcine-coronary-model
#5
Masayuki Mori, Kenji Sakata, Chiaki Nakanishi, Takuya Nakahashi, Masa-Aki Kawashiri, Kazuaki Yoshioka, Yoh Takuwa, Hirofumi Okada, Jun-Ichiro Yokawa, Masaya Shimojima, Tsuyoshi Yoshimuta, Shohei Yoshida, Masakazu Yamagishi, Kenshi Hayashi
Although Nobori(®), with a bioresorbable polymer and biolimus A9 abluminal coating, has unique characteristics, few data exist regarding endothelialization early after implantation. Fifteen Nobori(®) and 14 control bare-metal stents (S-stent™) were implanted in 12 pigs. Histopathology of stented segments, inflammation, and intimal fibrin content was evaluated on the 2nd and 14th day after implantation. On the 2nd day, endothelial cells were morphologically and immunohistologically confirmed on the surface of both stents, although some inflammatory cells might be involved...
May 17, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28515858/three-dimensional-optical-coherence-tomography-reconstruction-of-bifurcation-stenting-using-the-szabo-anchor-wire-technique
#6
Katherine Yu, Harkawal Hundal, Todd Zynda, Arnold Seto
Ostial lesions present unique challenges for percutaneous coronary intervention (PCI). These lesions are often more calcified, fibrotic, rigid, and more prone to elastic recoil. Intervention on these lesions is associated with higher procedural complications and higher rates of restenosis. Ostial lesions require precise stent placement in the ostium with the absence of side branch compromise. Accurate stent placement in the ostium without side branch compromise is difficult to accomplish with angiography alone...
April 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28513115/endarterectomy-or-stenting-in-severe-asymptomatic-carotid-stenosis
#7
Dallit Mannheim, Batla Falah, Ron Karmeli
BACKGROUND: Stroke is a major cause of death in the western world, and carotid endarterectomy has been shown to be effective in treating both symptomatic and asymptomatic carotid stenosis. Carotid stenting is a relatively new form of treatment for carotid stenosis and few studies have looked specifically at asymptomatic patients. OBJECTIVES: To retrospectively examine short- and long-term results in the treatment of asymptomatic carotid artery stenosis with surgery or stenting...
May 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28512285/coronary-aneurysm-formation-after-bioresorbable-vascular-scaffold-implantation-resulting-in-acute-myocardial-infarction
#8
Ching-Chang Fang, Yeun Tarl Fresner Ng Jao
BACKGROUND Development of a true coronary aneurysm after percutaneous coronary intervention is a rare event, and a coronary aneurysm resulting in acute myocardial infarction is even rarer. Coronary aneurysm formation after bioresorbable vascular scaffold (BVS) implantation, eventually leading to thrombosis, embolization, and myocardial infarction, has never been reported before in the literature. CASE REPORT A 62-year-old man received an elective BVS for a proximal left anterior descending lesion. Two months later, he suffered from a non-ST-segment myocardial infarction...
May 17, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28511925/total-correction-of-tetralogy-of-fallot-at-early-age-a-study-of-183-cases
#9
Mohamed Alassal, Bedir M Ibrahim, Hany M Elrakhawy, Magdy Hassenien, Sameh Sayed, Magdy Elshazly, Nabil Elsadeck
BACKGROUND: Opinions regarding the optimal time for the repair of tetralogy of Fallot vary. A debate also exists about the timing of repair for the asymptomatic infant. METHODS: This study included 183 patients with tetralogy of Fallot. All patients were subjected to clinical examination with measurement of oxygen saturation, 12-lead ECG, plain chest x-ray, and complete laboratory investigation. Echocardiography and cardiac catheterisation were indicated if there was an inability to reach diagnosis by echocardiography, suspicion of coronary anomaly, evaluation of distal pulmonary arteries or suspicion of major aorto-pulmonary collaterals...
April 27, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28511772/transcoronary-concentration-gradient-of-microrna-133a-and-outcome-in-patients-with-coronary-artery-disease
#10
Roberta De Rosa, Salvatore De Rosa, David Leistner, Jes-Niels Boeckel, Till Keller, Stephan Fichtlscherer, Stefanie Dimmeler, Andreas M Zeiher
Circulating levels of microRNA (miR)-133a are increased in patients with coronary atherosclerotic disease (CAD). Whether the cardiac release of this miR provides any prognostic information in patients with CAD is currently unknown. We aimed to investigate if changes in concentration of miR-133a trough the coronary circulation may be associated with patients' cardiovascular outcome. We enrolled 111 patients (82 with stable CAD and 29 with acute coronary syndromes [ACS]) who underwent coronary angiography. Circulating levels of miR-133a were measured across the transcoronary circulation...
April 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28511326/-comparison-of-aortic-annular-diameter-defined-by-different-measurement-mordalities-before-transcatheter-aortic-valve-implantation
#11
R X Qi, X D You, Z X Pu, Q Yang, Z X Huang, L M Zhou, P T Huang
Objective: To compare aortic annular diameter measured by transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and multislice computed tomography (MSCT) in patients with severe aortic stenosis, and to evaluate the impact on selection of prosthetic valve type in transcatheter aortic valve implantation (TAVI). Methods: Clinical data of 138 patients with severe aortic stenosis referred for TAVI between January 2014 and June 2016 in our hospital were retrospectively analyzed.The difference of aortic annular diameter measured by TTE, TEE, and MSCT were compared...
May 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28504232/portugal-coronary-and-structural-heart-interventions-from-2010-to-2015
#12
Rui Campante Teles, Gustavo Pires-Morais, Pedro Canas da Silva, Rui Cruz Ferreira, Manuel de Sousa Almeida, Filipe Seixo, Marco Costa, Vasco Gama Ribeiro, Jorge Marques, João Carlos Silva, Hélder Pereira, Pedro Farto E Abreu, Henrique Carvalho, Eduardo Infante de Oliveira
The aim of the present paper is to report trends in Portuguese interventional cardiology from 2010 to 2015. We studied data from the prospective multicentre Portuguese National Registry of Interventional Cardiology (RNCI) to analyse percutaneous coronary intervention (PCI) procedures and structural heart interventions from 2010 to 2015. A total of 73,977 PCIs and 780 transcatheter aortic valve implants were performed during the study period. Since 2010 there has been a 60% increase in PCI procedures and a twofold increase in primary angioplasty rates reaching 316 per million population...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504218/first-in-human-evaluation-of-a-novel-poly-l-lactide-based-sirolimus-eluting-bioresorbable-vascular-scaffold-for-the-treatment-of-de-novo-native-coronary-artery-lesions-meres-1-trial
#13
Ashok Seth, Yoshinobu Onuma, Ricardo Costa, Praveen Chandra, Vinay K Bahl, Cholenahally N Manjunath, Ajaykumar U Mahajan, Viveka Kumar, Pravin K Goel, Gurpreet S Wander, Mathew S Kalarickal, Upendra Kaul, V K Ajit Kumar, Pratap C Rath, Vijay Trehan, Gunasekaran Sengottuvelu, Sundeep Mishra, Alexandre Abizaid, Patrick W Serruys
AIMS: The MeRes-1 trial sought to study the safety and effectiveness of a novel sirolimus-eluting bioresorbable vascular scaffold (MeRes100 BRS) in treating de novo native coronary artery lesions by clinical evaluation and using multiple imaging modalities. METHODS AND RESULTS: The MeRes-1 first-in-human trial was a single-arm, prospective, multicentre study, which enrolled 108 patients with de novo coronary artery lesions (116 scaffolds were deployed to treat 116 lesions in 108 patients)...
May 16, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28503689/effects-of-elemene-on-inhibiting-proliferation-of-vascular-smooth-muscle-cells-and-promoting-reendothelialization-at-the-stent-implantation-site
#14
Wenjie Sun, Yuhua Huang, Tieying Yin, Jingjing Wang, Ruolin Du, Juhui Qiu, Yuan Zhang, Yazhou Wang, Jinju Chen, Guixue Wang
Anticancer drugs are commonly used as inhibitors of vascular smooth muscle cell (VSMC) proliferation in clinical treatments. This study aims to investigate how elemene affects the proliferation of VSMCs, the restenosis, and the reendothelialization after implanting the elemene-coated stents. VSMCs derived from rat aorta were used to test the cell proliferation, cell cycle, migration, apoptosis, cytoskeletal protein F-actin, intracellular Ca(2+), IncRNA chip and gene expression of PCNA, P53, and Cx43 when cultured with elemene...
May 15, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28502794/mir-125a-5p-modulates-phenotypic-switch-of-vascular-smooth-muscle-cells-by-targeting-ets-1
#15
C Gareri, C Iaconetti, S Sorrentino, C Covello, S De Rosa, C Indolfi
MicroRNAs are key regulators of vascular smooth muscle cells (VSMCs) phenotypic switch, one of the main events responsible for bare metal stent restenosis (ISR) after percutaneous coronary intervention (PCI). miR-125a-5p is an important modulator of differentiation, proliferation and migration in different cell types; however, its role in VSMCs is still unknown. The aim of this study was to evaluate the role of miR-125a-5p in VSMCs phenotypic switch. Our results suggest that miR-125a-5p is highly expressed in VSMCs, but it is down-regulated after vascular injury in vivo...
May 11, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28500738/occurrence-and-predictors-of-acute-stent-recoil-a-comparison-between-the-xience-prime-cobalt-chromium-stent-and-the-promus-premier-platinum-chromium-stent
#16
Rutger J van Bommel, Miguel E Lemmert, Nicolas M van Mieghem, Robert-Jan van Geuns, Ron T van Domburg, Joost Daemen
OBJECTIVES: To compare the occurrence of acute stent recoil in two different stent types (platinum chromium and cobalt chromium) and identify the potential predictors of significant acute stent recoil. BACKGROUND: Acute stent recoil is frequently observed after percutaneous coronary intervention and has been associated with in-stent restenosis and in-stent thrombosis. Different stent designs may result in varying degrees of stent recoil. METHODS: From a registry of "all-comers" treated with either the Xience Prime Cobalt Chromium or Promus Premier Platinum Chromium stent, a random sample of 100 patients was drawn...
May 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28499653/customized-hinged-covered-metallic-stents%C3%A2-for-the-treatment-of-benign-main-bronchial-stenosis
#17
Xinwei Han, Quazi Al-Tariq, Yanle Zhao, Lei Li, Zhe Cheng, Huaqi Wang, Chao Liu, Dechao Jiao, Gang Wu
BACKGROUND: To address the limitations of silicone stents, we designed a hinged self-expandable covered metallic stent. The aim of this study was to evaluate the safety and efficacy of the customized stents in clinical applications. METHODS: This was a retrospective analysis. Under conscious sedation and local anesthesia, the stents were implanted or removed by interventional radiologists, with fluoroscopic guidance. RESULTS: Of 24 patients with benign main bronchial stenosis, stents were successfully placed in 21 (87...
May 9, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28498849/percutaneous-coronary-intervention-with-second-generation-drug-eluting-stent-versus-bare-metal-stent-systematic-review-and-cost-benefit-analysis
#18
Thomas G Poder, Jihane Erraji, Lucien P Coulibaly, Kouamé Koffi
BACKGROUND: Drug-eluting stents (DESs) were considered as ground-breaking technology promising to eradicate restenosis and the necessity to perform multiple revascularization procedures subsequent to percutaneous coronary intervention. Soon after DESs were released on the market, however, there were reports of a potential increase in mortality and of early or late thrombosis. In addition, DESs are far more expensive than bare-metal stents (BMSs), which has led to their limited use in many countries...
2017: PloS One
https://www.readbyqxmd.com/read/28496557/in-stent-restenosis-due-to-stent-recoil-after-third-generation-drug-eluting-stent-implantation
#19
Yuta Kato, Atsushi Iwata, Masayuki Nakamura, Shin-Ichiro Miura, Keijiro Saku
A 72-year-old man with a heavily calcified coronary lesion underwent percutaneous coronary intervention (PCI) using a third-generation drug-eluting stent (DES) with thin stent struts. Two months after the PCI, in-stent restenosis due to stent recoil (SR) occurred. An intravascular ultrasound (IVUS) revealed deformed stent struts and heavily calcified coronary plaque. The SR probably occurred due to persistent vessel compression as a result of heavily calcified coronary plaque. We should consider using a DES with thick stent struts rather than a third-generation DES with thin stent struts in patients with a heavily calcified coronary lesion...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28492738/factors-associated-with-coronary-artery-disease-progression-assessed-by-serial-coronary-computed-tomography-angiography
#20
Gabriel Cordeiro Camargo, Tamara Rothstein, Maria Eduarda Derenne, Leticia Sabioni, João A C Lima, Ronaldo de Souza Leão Lima, Ilan Gottlieb
Background: Coronary computed tomography angiography (CCTA) allows for noninvasive coronary artery disease (CAD) phenotyping. Factors related to CAD progression are epidemiologically valuable. Objective: To identify factors associated with CAD progression in patients undergoing sequential CCTA testing. Methods: We retrospectively analyzed 384 consecutive patients who had at least two CCTA studies between December 2005 and March 2013. Due to limitations in the quantification of CAD progression, we excluded patients who had undergone surgical revascularization previously or percutaneous coronary intervention (PCI) between studies...
May 4, 2017: Arquivos Brasileiros de Cardiologia
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