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https://www.readbyqxmd.com/read/28651572/efficacy-of-a-seal-wing-paclitaxel-eluting-balloon-catheters-in-the-treatment-of-bare-metal-stent-restenosis
#1
Leos Pleva, Pavel Kukla, Jana Zapletalova, Ota Hlinomaz
BACKGROUND: Our study aimed to compare the efficacy of seal-wing paclitaxel-eluting balloon catheters (PEB) with iopromide-coated PEB and everolimus-eluting stents (EES) for treating bare metal stent restenosis (BMS-ISR). METHODS: We enrolled 64 patients with 69 BMS-ISR. The control group comprised patients from the iopromide-PEB and EES arms of a previous TIS study. The primary end-point was 12-month in-segment late lumen loss (LLL). Secondary end-points included incidence of binary in-stent restenosis and 12-month major adverse cardiac events (MACE)...
June 26, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28651349/an-autopsy-case-of-sudden-cardiac-death-due-to-in-scaffold-restenosis-and-late-scaffold-thrombosis-after-bioresorbable-vascular-scaffold-implantation-back-to-past-stent-era
#2
Kumiko Asakura, Hiroyuki Hao
No abstract text is available yet for this article.
June 22, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28649980/mid-term-outcomes-of-stent-overlap-in-long-total-occluded-lesions-of-superficial-femoral-artery
#3
Ulas Bildirici, Mujdat Aktas, Emir Dervis, Umut Celikyurt
BACKGROUND Superficial femoral artery chronic total occlusion (SCTO) is a common type of peripheral arterial disease (PAD). Endovascular therapy is a treatment approach that has a poor long-term success rate in this group. The aim of this study was to compare the mid-term results of two different uses of nitinol stents in long SCTO lesions (>100 mm): the use of one long stent or two shorter stents. MATERIAL AND METHODS Of 154 patients who underwent percutaneous infrainguinal interventions from 2011 to 2014, a total of 170 CTO lesions were selected for this retrospective study analysis...
June 26, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28649953/clinical-restenosis-and-its-predictors-after-implantation-of-everolimus-eluting-bioresorbable-vascular-scaffolds-results-from-the-gabi-r-registry
#4
Julinda Mehilli, Stephan Achenbach, Jochen Woehrle, Moritz Baquet, Thomas Riemer, Thomas Muenzel, Holger Nef, Christoph Naber, Gert Richardt, Ralf Zahn, Tommaso Gori, Till Neumann, Johannes Kastner, Axel Schmermund, Christian Hamm
AIMS: To assess clinical restenosis and its predictors after implantation bioresorbable vascular scaffolds (BVS) in everyday practice in the large scale German-Austrian ABSORB Registry (GABI-R). METHODS AND RESULTS: Between November 2013 and January 2016, 3264 patients underwent BVS implantion in 93 centers of GABI-R. At 6-month follow-up, 24 patients experienced clinically-indicated target lesion revascularization (cTLR) unrelated to BVS thrombosis (cumulative incidence 0...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28649088/targeting-aggf1-angiogenic-factor-with-g-patch-and-fha-domains-1-for-blocking-neointimal-formation-after-vascular-injury
#5
Yufeng Yao, Zhenkun Hu, Jian Ye, Changqing Hu, Qixue Song, Xingwen Da, Yubin Yu, Hui Li, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang
BACKGROUND: Despite recent improvements in angioplasty and placement of drug-eluting stents in treatment of atherosclerosis, restenosis and in-stent thrombosis impede treatment efficacy and cause numerous deaths. Research efforts are needed to identify new molecular targets for blocking restenosis. We aim to establish angiogenic factor AGGF1 (angiogenic factor with G patch and FHA domains 1) as a novel target for blocking neointimal formation and restenosis after vascular injury. METHODS AND RESULTS: AGGF1 shows strong expression in carotid arteries; however, its expression is markedly decreased in arteries after vascular injury...
June 25, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28649050/new-light-on-second-generation-drug-eluting-stent-restenosis
#6
Nieves Gonzalo, Nicola Ryan, Javier Escaned
No abstract text is available yet for this article.
June 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28648794/in-vitro-and-in-vivo-evaluation-of-a-coaxial-electrospun-small-caliber-vascular-graft-loaded-with-heparin-and-vegf
#7
Yuntao Hu, Xudong Pan, Jun Zheng, Weiguo Ma, Lizhong Sun
INTRODUCTION: To date, clinically available expanded polytetrafluoro- Ethylene (ePTFE) vascular grafts are suboptimal for reconstructing small Caliber (D<;6mm)arteries, owing to thrombosis in early and restenosis in; late stage. Our aim in this preliminary study was to fabricate a nano-fibrous vascular graft which was biofunctionalized with VEGF and hepa-rin. The short term performance was evaluated both in vitro and in vivo. METHOD: 4 mm caliber grafts were prepared by the coaxial-elctrospun technique, which consisted of poly (l-lactide-co-caprolactone) [P (LLA-CL)] collagen and elastin...
June 22, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28648791/drug-eluting-stents-versus-control-therapy-in-the-infrapopliteal-disease-a-meta-analysis-of-eight-randomized-controlled-trials-and-two-cohort-studies
#8
REVIEW
Xiaochun Liu, Guofu Zheng, Song Wen
BACKGROUD: Drug-eluting stents (DES) have been proposed for the treatment of infrapopliteal arteries disease. However, the long-term clinical impact of DES treatment in the vascular territory still remains uncertain. METHODS AND RESULTS: Pubmed, Embase, Cochrane data, CNKI and Wanfang Data were searched until December 20, 2016 for eligible studies according to identical strategies. Additional data were manually retrieved. STATA ver. 12.0 software were used to Meta-analyze the efficacies of DES and control treatment (BMS or PTA) for infrapopliteal arteries disease...
June 22, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28648653/long-term-results-of-tapered-stents-in-endovascular-treatment-of-carotid-stenosis
#9
Gioele Simonte, Beatrice Fiorucci, Giacomo Isernia, Gianbattista Parlani, Fabio Verzini, Enrico Cieri, Massimo Lenti
BACKGROUND: Recent technological developments allowed significant improvements in interventional approach to carotid artery stenosis. Tapered stents were specifically designed for extracranial carotid artery stenting (CAS) to deal with vessels mismatch with the objective of decreasing the risk of thrombosis. Nevertheless, whether the stent geometry may affect the outcomes of CAS is uncertain. This study aims to investigate the impact of stent configuration on perioperative and long term results of this procedure...
June 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28647998/-analysis-of-optical-coherence-tomography-of-early-and-very-late-stent-restenosis-after-drug-eluting-stent-implantation
#10
Z J Liu, B Shi, C C Deng, G X Xu, R Z Zhao, C Y Shen, Z L Wang, H L Liu
Objective: Using optical coherence tomography (OCT) to analyze the morphological characteristics of lesions between early in-stent restenosis (E-ISR) and very late in-stent restenosis (VL-ISR) after drug-eluting stents (DES) implantation. Methods: In 25 patients (DES) with ISR, OCT images were acquired before percutaneous coronary intervention (PCI), the morphological characteristics of E-ISR (<1 years, n=14) and VL-ISR (>3 years, n=11) were compared.The quantitative and qualitative analysis of the entire stent and the minimum lumen area (MLA) site were carried out respectively...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647637/transcervical-carotid-artery-stenting-using-a-prosthetic-arterial-conduit-case-series-of-a-novel-surgical-technique
#11
Nandakumar Menon, Ali Khalifeh, Charles B Drucker, Suny Sahajwani, Danon Garrido, Richa Kalsi, Brajesh K Lal, Shahab Toursavadkohi
We present a series of 4 patients with carotid restenosis following carotid endarterectomy (CEA) who underwent transcervical carotid artery stenting (CAS) using a novel prosthetic conduit technique. The patients were high risk for repeat CEA (short and obese necks) and had contraindications to transfemoral CAS (Bovine arch, prior dissection). Carotid artery stenting was thus performed via a transcervical approach with a polytetrafluoroethylene (PTFE) conduit anastomosed to the proximal common carotid artery (CCA)...
June 21, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28647315/safety-and-efficacy-of-new-biodegradable-polymer-based-sirolimus-eluting-stents-in-a-preclinical-model
#12
Armando Pérez de Prado, Claudia Pérez Martínez, Carlos Cuellas Ramón, Marta Regueiro Purriños, María López Benito, José Manuel Gonzalo Orden, José Antonio Rodríguez Altónaga, Rodrigo Estévez Loureiro, Tomás Benito González, David Viñuela Baragaño, María Molina Crisol, Marc Amorós Aguilar, Isabel Pérez Serranos, Arnau Vidal Parreu, Ana Benavides Montegordo, Luis Duocastella Codina, Felipe Fernández Vázquez
INTRODUCTION AND OBJECTIVES: New drug-eluting stents (DES) designed to overcome the limitations of existing devices should initially be tested in preclinical studies. Our objective was to analyze the safety and efficacy of new biodegradable polymer-based DES compared with bare-metal stents (BMS) and commercially available DES in a model of normal porcine coronary arteries. METHODS: We randomly implanted 101 stents (BMS and biodegradable polymer-based sirolimus-eluting stents: 3 test stent iterations [BD1, BD2, and BD3], Orsiro, Biomime and Biomatrix) in the coronary arteries of 34 domestic pigs...
June 21, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28645858/vascular-adaptation-pattern-formation-and-cross-validation-between-an-agent-based-model-and-a-dynamical-system
#13
Marc Garbey, Stefano Casarin, Scott A Berceli
Myocardial infarction is the global leading cause of mortality (Go AS et al. 2014). Coronary artery occlusion is its main etiology and it is commonly treated by Coronary Artery Bypass Graft (CABG) surgery (Wilson CT 2007). The long-term outcome remains unsatisfactory (Benedetto U 2016). The vein faces the phenomenon of restenosis during the post-surgery, which consists of re-occlusion of the lumen and usually requires secondary intervention even within one year after the initial surgery (Harskamp RE 2013). We propose an extensive study of the restenosis phenomenon by implementing two mathematical models previously developed: a heuristic Dynamical System (DS) (Garbey M and Berceli SA 2013), and a stochastic Agent Based Model (ABM) (Garbey M et al...
June 20, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28645655/5-lipoxygenase-in-monocytes-emerges-as-a-therapeutic-target-for-intimal-hyperplasia-in-a-murine-wire-injured-femoral-artery
#14
Seung Eun Baek, Min A Jang, Seung Jin Lee, So Youn Park, Sun Sik Bae, Chi Dae Kim
Given the importance of leukotrienes in vascular inflammation induced by local tissue injury, this study investigated the role for 5-lipoxygenase (5-LO) in monocytes in the development of intimal hyperplasia. As a mechanistic study, the importance of monocyte 5-LO in monocyte-macrophage differentiation with subsequent infiltration in neointima was evaluated. In a mouse model of wire-injured femoral artery, intimal hyperplasia started as early as 2 wks after injury, and luminal area and blood flow were reduced due to increased neointima formation...
June 20, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28644215/treatment-of-coronary-stent-restenosis-with-drug-eluting-bioabsorbable-magnesium-scaffolds
#15
Fernando Alfonso, Javier Cuesta, Marcos García-Guimaraes, Teresa Bastante, Ramón Maruri, Fernando Rivero
No abstract text is available yet for this article.
June 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28641033/evaluation-of-planned-bicanalicular-nasolacrimal-tube-retention-in-treating-punctal-stenosis-or-occlusion-secondary-to-trachoma
#16
Rania A Ahmed, Ahmed M Kamal, Mohamed A Zayed
This article evaluates retaining bicanalicular silicone nasolacrimal tube in patients susceptible to restenosis after punctoplasty. Sixty-nine eyes (38 patients) suffering from epiphora due to stenosis or occlusion of both punctae were included in this prospective study. All had 3 snip punctoplasty and bicanalicular silicone nasolacrimal duct insertion. Cases associated with proximal canalicular stenosis or obstructions were excluded. Tolerance to tube presence until the time of loss or removal was evaluated using a score (0 to 2)...
June 22, 2017: Orbit
https://www.readbyqxmd.com/read/28637016/socs1-gene-promoter-methylation-status-is-associated-with-in-stent-restenosis-after-percutaneous-coronary-intervention
#17
Liang Zhou, Ningfu Wang, Hong Li, Guoxin Tong, Jianmin Yang, Lei Lai, Hao Pan, Xianhua Ye, Jinyu Huang
BACKGROUND: Inflammation is involved in the development of In-stent restenosis (ISR) after percutaneous coronary intervention. We aimed to investigate the association between of suppressor of cytokine signaling-1 (SOCS1), a major negative regulator for inflammation, and the occurrence of ISR in Chinese patients. METHODS: We enrolled patients with coronary artery disease who underwent PCI with stenting. PCI procedures were performed successfully and a follow-up angiography was repeated 1 year later to determine ISR presence...
June 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636237/microperforate-hymen-presenting-with-incomplete-abortion-a-case-report
#18
Maya Padhi, Priyadarshini Tripathy, Asutosh Sahu
A 20-year-old patient with 3 months of amenorrhea presented in the labor room with bleeding per vaginum and having experienced lower abdominal pain for 2 h. She had a history of difficult intercourse and prolonged menstrual flow. Inspection revealed a bleeding point over an obstructing membrane at the level of the vaginal introitus. Subsequent vaginal examination confirmed the diagnosis of microperforate hymen. Her urine pregnancy test was positive and an ultrasound examination revealed the presence of retained products of conception in the endometrial cavity...
June 21, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28635304/the-relationship-between-the-neutrophil-lymphocyte-ratio-and-in-stent-restenosis-in-patients-with-femoropopliteal-chronic-total-occlusions
#19
Zhihui Chang, Jiahe Zheng, Zhaoyu Liu, Qiyong Guo
We investigated the relationship between the neutrophil-lymphocyte ratio (NLR) and in-stent restenosis (ISR) in patients with femoropopliteal chronic total occlusions (CTOs). The study enrolled 180 patients who had undergone successful stenting treatment for femoropopliteal CTO. Patients with ISR were subsequently classified into 2 groups: early-ISR (within 1 year) and late-ISR (after 1 year). The clinical characteristics, angiographic data, and follow-up data were recorded. The baseline NLR was significantly higher in the early-ISR group than that in the non-ISR group [3...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28633223/primary-pulmonary-vein-stenosis-outcomes-risk-factors-and-severity-score-in-a-multicentric-study
#20
David Kalfa, Emre Belli, Emile Bacha, Virginie Lambert, Duccio di Carlo, Martin Kostolny, Jukka Salminen, Matej Nosal, Alain Poncelet, Jurgen Horer, Hakan Berggren, Illya Yemets, Mark Hazekamp, Bohdan Maruszewski, George Sarris, Marco Pozzi, Tjark Ebels, François Lacour-Gayet
BACKGROUND: Primary pulmonary vein stenosis (PPVS) still carries a poor prognosis, and prognostic factors remain controversial. The aim of this study was to determine outcomes and prognostic factors after PPVS repair in the current era. METHODS: Thirty patients with PPVS and a normal pulmonary vein (PV) connection operated on in 10 European/North American centers (2000-2012) were included retrospectively. A specific PVS severity score was developed based on the assessment of each PV...
July 2017: Annals of Thoracic Surgery
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