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https://www.readbyqxmd.com/read/27923262/circulating-levels-of-lamp2-in-coronary-artery-disease-association-with-serum-lipid-profile
#1
M Teimouri, P Shabani, F Zali, M Najafi, H Shateri, M Asadnia, A Vatannejad, M Najafi, M Doosti
Whereas several in vitro and in vivo studies have described the role of lysosomal associated membrane protein 2 (LAMP2) in lipid homeostasis, there is no study addressing LAMP2 serum concentration and its association with lipid profiles in the context of coronary artery disease (CAD). We aimed to determine the LAMP2 serum concentration and its association with serum lipid profiles as well as the gene expression of LAMP2 in peripheral blood mononuclear cells (PBMCs) of CAD patients and control group. Circulating levels of LAMP2 were quantified by enzyme-linked immunosorbent assay (ELISA) in CAD patients (n=85) and control group (n=65) and correlation to lipid parameters was assessed...
December 6, 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/27923194/gender-negative-life-events-and-coping-on-different-stages-of-depression-severity-a-cross-sectional-study-among-chinese-university-students
#2
Xiao-Jun Sun, Geng-Feng Niu, Zhi-Qi You, Zong-Kui Zhou, Yun Tang
BACKGROUND: The effects of gender, negative life events, and coping on depression have been well-documented. But depression is a heterogeneous syndrome of which the severity ranged from mild depression to major depression. This study aimed to investigate the specific effects of gender, negative life events, and coping on different stages of depression severity. METHOD: A total of 5989 students (aged 16-25 years, M=20.85, SD=0.58), recruited from six universities in the central region of China using the stratified cluster sampling method, completed Life Events Questionnaire, Coping Response Inventory, and Beck Depression Inventory-Ⅱ...
November 19, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27922969/orbital-morphometry-a-computed-tomography-analysis
#3
Jaswinder Singh, Roselinda Ab Rahman, Zainul Ahmad Rajion, Johari Abdullah, Irfan Mohamad
INTRODUCTION: The human orbit is a complex anatomic region, which plays predominant role in the evaluation of craniofacial complex. A thorough understanding of the relationship of the distance from orbital rim to the important vital structures of the orbital apex is required for the surgeon to perform safe and effective surgery. OBJECTIVES: To evaluate and compare the depth and distances from various points of the orbital rim to the fissures and foramina of the orbital apex between genders in the local population...
December 5, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27921321/from-paperwork-to-parenting-experiences-of-professional-staff-in-student-support
#4
Wendy C Y Hu, Eleanor Flynn, Rebecca Mann, Robyn Woodward-Kron
CONTEXT: For academic staff, responding to student concerns is an important responsibility. Professional staff, or non-academic staff who do administrative work in medical schools, are often the first to be approached by students, yet there is little research on how they manage student issues. Informed by the conceptual framework of emotional labour, we examined the experiences of professional staff, aiming to identify theoretical and practical insights for improving the provision of student support...
December 5, 2016: Medical Education
https://www.readbyqxmd.com/read/27920118/patients-views-on-general-practitioners-role-during-treatment-and-follow-up-of-colorectal-cancer-a-qualitative-study
#5
Daan Brandenbarg, Carriene Roorda, Michelle Stadlander, Geertruida H de Bock, Marjolein Y Berger, Annette J Berendsen
PURPOSE: To clarify experiences and preferences of patients regarding the current and future role of GPs during treatment and follow-up care of colorectal cancer (CRC). METHODS: Qualitative semi-structured, audio-recorded, face-to-face interviews in patients' homes in the north of the Netherlands were performed. Patients were sampled purposively on age, gender, time since diagnoses and primary health care use. Data were transcribed verbatim and analysed thematically by two independent researchers until saturation was reached...
December 5, 2016: Family Practice
https://www.readbyqxmd.com/read/27919303/mental-illness-stigma-and-suicidality-the-role-of-public-and-individual-stigma
#6
N Oexle, T Waldmann, T Staiger, Z Xu, N Rüsch
AIMS: Suicide rates are increased among unemployed individuals and mental illness stigma can contribute to both unemployment and suicidality. Persons with mental illness perceive negative attitudes among the general public and experience discrimination in their everyday life (=public stigma components) potentially leading to self-stigma and anticipated discrimination (=individual stigma components). Previous research found evidence for an association between aspects of mental illness stigma and suicidality, but has not yet clarified the underlying pathways explaining how different stigma components interact and contribute to suicidal ideation...
December 6, 2016: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/27919238/an-equity-analysis-of-utilization-of-health-services-in-afghanistan-using-a-national-household-survey
#7
Christine Kim, Khwaja Mir Ahad Saeed, Ahmad Shah Salehi, Wu Zeng
BACKGROUND: Afghanistan has made great strides in the coverage of health services across the country but coverage of key indicators remains low nationally and whether the poorest households are accessing these services is not well understood. METHODS: We analyzed the Afghanistan Mortality Survey 2010 on utilization of inpatient and outpatient care, institutional delivery and antenatal care by wealth quintiles. Concentration indexes (CIs) were generated to measure the inequality of using the four services...
December 5, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27918427/prolactin-friend-or-foe-in-central-nervous-system-autoimmune-inflammation
#8
REVIEW
Massimo Costanza, Rosetta Pedotti
The higher prevalence of multiple sclerosis (MS) in females, along with the modulation of disease activity observed during pregnancy and the post-partum period, has suggested a hormonal influence in MS. Even if prolactin (PRL) does not belong to the sex hormones family, its crucial role in female reproduction and lactation has prompted great efforts to understand if PRL could represent a gender factor in the pathogenesis of MS and experimental autoimmune encephalomyelitis (EAE), the animal model for this disease...
December 2, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27918172/an-experimental-test-of-the-bridges-to-high-school-intervention-on-harsh-parenting-and-early-age-intercourse-among-mexican-american-adolescents
#9
Miguelina Germán, Nancy A Gonzales, Stephen G West, Lorey A Wheeler
OBJECTIVE: Can an intervention that contained no content on sex or contraception reduce rates of early-age intercourse among Mexican American adolescents? The current study examined whether the Bridges to High School intervention designed, in part, to decrease harsh parenting, had a longitudinal effect on decreasing rates of early-age intercourse in the treatment versus control groups, as well as the moderating role of gender and linguistic acculturation. METHOD: The sample consisted of 516 Mexican American adolescents (Mage = 12...
December 5, 2016: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/27918062/harm-aversion-explains-utilitarian-choices-in-moral-decision-making-in-males-but-not-in-females
#10
G Rota, S Palumbo, N Lattanzi, A Manfrinati, M Sarlo, L Lotto, P Pietrini, R Rumiati, S Pellegrini
In recent years, a great deal of research has relied on hypothetical sacrificial dilemmas to investigate decision-making processes involved in pro-social utilitarian choices. Recent evidence, however, has suggested that moral sacrificial choices may actually reflect reduced harm aversion and antisocial dispositions rather than an utilitarian inclination. Here, we used moral dilemmas to confront healthy volunteers with controversial action choices. We measured impulsiveness and venturesomeness personality traits, which have been shown to influence harm aversion, to test their role in utilitarian action and evaluation of moral acceptability...
June 1, 2016: Archives Italiennes de Biologie
https://www.readbyqxmd.com/read/27917492/predictors-of-developing-mathematics-anxiety-among-middle-school-students-a-2-year-prospective-study
#11
Nir Madjar, Gil Zalsman, Abraham Weizman, Shaul Lev-Ran, Gal Shoval
While there is an abundance of research pertaining to the development of anxiety disorders, there is still a dearth of knowledge regarding the development of anxiety in the general population. The objective of this study was to longitudinally explore the development of mathematics anxiety among normative middle-school students, and to identify the moderating role of gender, school transition and scholastic achievements on these trajectories. Subjects included 413 sixth grade students (53.3% females, mean age 11...
December 4, 2016: International Journal of Psychology: Journal International de Psychologie
https://www.readbyqxmd.com/read/27917145/illegitimate-tasks-as-an-impediment-to-job-satisfaction-and-intrinsic-motivation-moderated-mediation-effects-of-gender-and-effort-reward-imbalance
#12
Rachel Omansky, Erin M Eatough, Marcus J Fila
The current work examines a contemporary workplace stressor that has only recently been introduced into the literature: illegitimate tasks. Illegitimate tasks are work tasks that violate identity role norms about what can reasonably be expected from an employee in a given position. Although illegitimate tasks have been linked to employee well-being in past work, we know little about the potential explanatory mechanisms linking illegitimate tasks to work-relevant negative psychological states. Using a sample of 213 US-based employees of mixed occupations and a cross-sectional design, the present study examines job satisfaction and intrinsic motivation as outcomes of illegitimate tasks...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27917142/perceived-interpersonal-burdensomeness-as-a-mediator-between-nightmare-distress-and-suicidal-ideation-in-nightmare-sufferers
#13
Sooyeon Suh, Matthew Schneider, Ruda Lee, Thomas Joiner
Previous studies have supported the significant association between nightmares and suicidal ideation, but the underlying mechanisms are largely unknown. The purpose of the present study was to investigate perceived burdensomeness and thwarted belongingness as mediators in the relationship between nightmare distress and suicidal ideation. This sample consisted of 301 undergraduate students who endorsed experiencing nightmares (mean age 21.87 ± 2.17, 78.1% female). All participants completed questionnaires on nightmare distress (Nightmare Distress Questionnaire), unmet interpersonal needs (Interpersonal Needs Questionnaire), and suicidal ideation (Depressive Symptom Inventory - Suicidality Subscale)...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27917140/can-illness-perceptions-predict-lower-heart-rate-variability-following-acute-myocardial-infarction
#14
Mary Princip, Marco Scholz, Rebecca E Meister-Langraf, Jürgen Barth, Ulrich Schnyder, Hansjörg Znoj, Jean-Paul Schmid, Julian F Thayer, Roland von Känel
Objective: Decreased heart rate variability (HRV) has been reported to be a predictor of mortality after myocardial infarction (MI). Patients' beliefs and perceptions concerning their illness may play a role in decreased HRV. This study investigated if illness perceptions predict HRV at 3 months following acute MI. Methods: 130 patients referred to a tertiary cardiology center, were examined within 48 h and 3 months following acute MI. At admission, patients' cognitive representations of their MI were assessed using the German version of the self-rated Brief Illness Perception Questionnaire (Brief IPQ)...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27916684/the-impact-of-obesity-on-compensatory-mechanisms-in-response-to-progressive-sagittal-malalignment
#15
Cyrus M Jalai, Bassel G Diebo, Dana L Cruz, Gregory W Poorman, Shaleen Vira, Aaron J Buckland, Renaud Lafage, Shay Bess, Thomas J Errico, Virginie Lafage, Peter G Passias
BACKGROUND CONTEXT: Obesity's impact on standing sagittal alignment remains poorly understood, especially with respect to the role of the lower-limbs. Given energetic expenditure in standing, a complete understanding of compensation in obese patients with sagittal malalignment remains relevant. PURPOSE: This study compares obese and non-obese patients with progressive sagittal malalignment for differences in recruitment of pelvic and lower limb mechanisms. STUDY DESIGN/SETTING: Single center retrospective review...
December 1, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27916515/oestrogen-and-anti-androgen-therapy-for-transgender-women
#16
REVIEW
Vin Tangpricha, Martin den Heijer
Transgender women experience lifelong gender dysphoria due to a gender assignment at birth that is incongruent with their gender identity. They often seek hormone therapy, with or without surgery, to improve their gender dysphoria and to better align their physical and psychological features with a more feminine gender role. Some of the desired physical changes from oestrogen and anti-androgen therapy include decreased body and facial hair, decreased muscle mass, breast growth, and redistribution of fat. Overall the risks of treatment are low, but include thromboembolism, the risk of which depends on the dose and route of oestrogen administration...
December 1, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27916380/contemporary-outcomes-of-open-thoracoabdominal-aneurysm-repair-functional-status-is-the-strongest-predictor-of-perioperative-mortality
#17
Tammam Obeid, Caitlin W Hicks, Kanhua Yin, Isibor Arhuidese, Besma Nejim, Arman Kilic, James H Black, Mahmoud Malas
BACKGROUND: Open repair of thoracoabdominal and descending thoracic aneurysm (TAA) carries significant operative morbidity and mortality. Despite evolving operative techniques patient-level risk factors affecting mortality after open TAA repair, including patient functional status, remain to be fully understood. MATERIALS AND METHODS: We identified all open TAA repair cases in the National Surgical Quality Improvement Program database between 2005 and 2013. Multivariable logistic regression was used to evaluate the effect of patients' age, gender, race, body mass index (BMI), comorbid conditions, functional status, ASA class, smoking, rupture, descending thoracic aneurysm versus Crawford types, dissection, and preoperative: transfusion, creatinine levels, on perioperative (30-d) mortality after open TAA repair...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27915341/rs1501299-polymorphism-in-the-adiponectin-gene-and-their-association-with-total-adiponectin-levels-insulin-resistance-and-metabolic-syndrome-in-obese-subjects
#18
Daniel Antonio de Luis, Olatz Izaola, Beatriz de la Fuente, David Primo, Hilda Fernandez Ovalle, Enrique Romero
BACKGROUND AND AIMS: The aim of this study was to determine the association of single nucleotide polymorphism rs1501299 in the ADIPOQ gene with body weight, insulin resistance, serum adipokine levels and metabolic syndrome (MetS). METHODS: The study involved a population of 1,007 adult obese subjects. Parameters like body weight, fat mass, waist circumferences, blood pressure, fasting blood glucose, C-reactive protein, insulin concentration, homeostasis model assessment for insulin resistance (HOMA-IR), lipid profile and adipocytokines levels (leptin, adiponectin and resistin) were all measured...
December 3, 2016: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/27915215/cha2ds2-vasc-hsf-score-new-predictor-of-severity-of-coronary-artery-disease-in-2976-patients
#19
Ranjan Modi, S V Patted, P C Halkati, Sanjay Porwal, Sameer Ambar, Prasad Mr, Vijay Metgudmath, Ameet Sattur
BACKGROUND: CHADS2 and CHA2DS2-VASc scores have been used for assessing prognostic risk of thromboembolism in non valvular atrial fibrillation patients. They include similar risk factors for the development of CAD To increase the likelihood of determining CAD severity, the CHA2DS2-VASc-HS and CHA2DS2-VASc-HSF score comprising of hyperlipidemia, smoking and family history respectively in addition to the components of the CHA2DS2-VASc score and male instead of female gender. The aim was to investigate whether these risk scores can be used to predict CAD severity...
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27914864/serum-dhea-s-concentration-correlates-with-clinical-symptoms-and-neurocognitive-function-in-patients-with-bipolar-ii-disorder-a-case-controlled-study
#20
Sheng-Yu Lee, Liang-Jen Wang, Cheng-Ho Chang, Chih-Ching Wu, Hsing-Ling Chen, Shih-Hsien Lin, Chin-Liang Chu, Ti Lu, Ru-Band Lu
OBJECTIVES: Dysregulation of the neuroendocrine system including dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and pregnenolone may play a role in the pathophysiology of bipolar II disorder (BP-II). The aims of the current study are to determine (a) the differences in DHEA, DHEA-S and pregnenolone in patients with BP-II and controls; and (b) the correlation of levels of the above hormones, cognitive function, and clinical symptoms. METHODS: Patients diagnosed with BP-II and healthy controls were recruited from psychiatric department...
November 30, 2016: Progress in Neuro-psychopharmacology & Biological Psychiatry
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