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https://www.readbyqxmd.com/read/28231614/risk-factors-for-the-development-of-post-traumatic-stress-disorder-and-coping-strategies-in-mothers-and-fathers-following-infant-hospitalization-in-the-neonatal-intensive-care-unit
#1
Anna Aftyka, Beata Rybojad, Wojciech Rosa, Aleksandra Wróbel, Hanna Karakuła-Juchnowicz
OBJECTIVE: The development of Neonatal Intensive Care Units (NICUs) has increased the survival rate of infants. However, one of the major parental problems is post-traumatic stress disorder (PTSD). The aim of this study was to identify the potential risk factors for the development of PTSD in mothers and fathers following infant hospitalization in the NICU. DESIGN: An observational study covered 125 parents (72 mothers and 53 fathers) of infants aged three to 12 months who were hospitalized in the NICU during the neonatal period...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28230804/calcium-intake-and-nutritional-adequacy-in-spanish-children-the-aniva-study
#2
Nuria Rubio-López, Agustín Llopis-González, María Morales-Suárez-Varela
Calcium is an important nutrient for child development. The main objective of this study was to assess calcium intake and its adequacy with dietary reference intake (DRI) in Spanish children. The ANIVA (Antropometría y Nutrición Infantil de Valencia) study is a descriptive cross-sectional study. During two academic years 2013-2014 and 2014-2015, 1176 schoolchildren aged 6-9 years were selected from 14 primary schools in Valencia (Spain). Three-day food records were used to assess dietary intake, completed by parents/guardian...
February 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28230321/disruption-of-genes-involved-in-corvet-complex-leads-to-enhanced-secretion-of-heterologous-carboxylesterase-only-in-protease-deficient-pichia-pastoris
#3
Lukas Marsalek, Clemens Gruber, Friedrich Altmann, Markus Aleschko, Diethard Mattanovich, Brigitte Gasser, Verena Puxbaum
The methylotrophic yeast Pichia pastoris (Komagataella spp.) is a popular microbial host for the production of recombinant proteins. Previous studies have shown that mis-sorting to the vacuole can be a bottleneck during production of recombinant secretory proteins in yeast, however, no information was available for P. pastoris. In this work we have therefore generated vps (vacuolar protein sorting) mutant strains disrupted in genes involved in the CORVET tethering complex at the early stages of endosomal sorting...
February 23, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28230275/the-development-and-correlates-of-gender-role-attitudes-in-african-american-youth
#4
Chun Bun Lam, Christine Stanik, Susan M McHale
This research examined the longitudinal trajectories and family correlates of gender role attitudes in African American youth in a sample of 166 sibling pairs residing with their mothers and fathers. Multilevel modelling revealed that (1) girls and boys exhibited significant declines in gender attitude traditionality from ages 9 to 15 that levelled off through age 18, (2) mothers' (but not fathers') gender role attitude traditionality was positively related to youth's attitude traditionality, and (3) within-person variation in mothers' (but not fathers') racial discrimination experiences was negatively related to within-person variation in youth's gender role attitude traditionality...
February 23, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/28229455/maternal-perinatal-and-concurrent-depressive-symptoms-and-child-behavior-problems-a-sibling-comparison-study
#5
Line C Gjerde, Espen Moen Eilertsen, Ted Reichborn-Kjennerud, Tom A McAdams, Henrik Daae Zachrisson, Imac Maria Zambrana, Espen Røysamb, Kenneth S Kendler, Eivind Ystrom
BACKGROUND: Previous studies have found significant associations between maternal prenatal and postpartum depression and child behavior problems (CBP). The present study investigates whether associations remain in a prospective, longitudinal design adjusted for familial confounding. METHODS: The sample comprised 11,599 families including 17,830 siblings from the Norwegian Mother and Child Cohort study. Mothers reported depressive symptoms at gestational weeks 17 and 30, as well as 6 months, 1...
February 23, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28229248/promoting-social-nurturance-and-positive-social-environments-to-reduce-obesity-in-high-risk-youth
#6
REVIEW
Dawn K Wilson, Allison M Sweeney, Heather Kitzman-Ulrich, Haylee Gause, Sara M St George
Nurturing environments within the context of families, schools, and communities all play an important role in enhancing youth's behavioral choices and health outcomes. The increasing prevalence rates of obesity among youth, especially among low income and ethnic minorities, highlight the need to develop effective and innovative intervention approaches that promote positive supportive environments across different contexts for at-risk youth. We propose that the integration of Social Cognitive Theory, Family Systems Theory, and Self-Determination Theory offers a useful framework for understanding how individual, family, and social-environmental-level factors contribute to the development of nurturing environments...
February 22, 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28228845/histone-and-dna-methylation-control-by-h3-serine-10-threonine-11-phosphorylation-in-the-mouse-zygote
#7
Jie Lan, Konstantin Lepikhov, Pascal Giehr, Joern Walter
BACKGROUND: In the mammalian zygote, epigenetic reprogramming is a tightly controlled process of coordinated alterations of histone and DNA modifications. The parental genomes of the zygote show distinct patterns of histone H3 variants and distinct patterns of DNA and histone modifications. The molecular mechanisms linking histone variant-specific modifications and DNA methylation reprogramming during the first cell cycle remain to be clarified. RESULTS: Here, we show that the degree and distribution of H3K9me2 and of DNA modifications (5mC/5hmC) are influenced by the phosphorylation status of H3S10 and H3T11...
2017: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/28228768/genome-wide-single-nucleotide-polymorphisms-in-cms-and-restorer-lines-discovered-by-genotyping-using-sequencing-and-association-with-marker-combining-ability-for-12-yield-related-traits-in-oryza-sativa-l-subsp-japonica
#8
Imdad U Zaid, Weijie Tang, Erbao Liu, Sana U Khan, Hui Wang, Edzesi W Mawuli, Delin Hong
Heterosis or hybrid vigor is closely related with general combing ability (GCA) of parents and special combining ability (SCA) of combinations. The evaluation of GCA and SCA facilitate selection of parents and combinations in heterosis breeding. In order to improve combining ability (CA) by molecular marker assist selection, it is necessary to identify marker loci associated with the CA. To identify the single nucleotide polymorphisms (SNP) loci associated with CA in the parental genomes of japonica rice, genome-wide discovered SNP loci were tested for association with the CA of 18 parents for 12 yield-related traits...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28228131/whole-genome-sequencing-of-one-complex-pedigree-illustrates-challenges-with-genomic-medicine
#9
Han Fang, Yiyang Wu, Hui Yang, Margaret Yoon, Laura T Jiménez-Barrón, David Mittelman, Reid Robison, Kai Wang, Gholson J Lyon
BACKGROUND: Human Phenotype Ontology (HPO) has risen as a useful tool for precision medicine by providing a standardized vocabulary of phenotypic abnormalities to describe presentations of human pathologies; however, there have been relatively few reports combining whole genome sequencing (WGS) and HPO, especially in the context of structural variants. METHODS: We illustrate an integrative analysis of WGS and HPO using an extended pedigree, which involves Prader-Willi Syndrome (PWS), hereditary hemochromatosis (HH), and dysautonomia-like symptoms...
February 23, 2017: BMC Medical Genomics
https://www.readbyqxmd.com/read/28228124/mediators-of-the-association-between-parental-education-and-breakfast-consumption-among-adolescents-the-essens-study
#10
Mekdes K Gebremariam, Sigrun Henjum, Elisabeth Hurum, Jorunn Utne, Laura Terragni, Liv Elin Torheim
BACKGROUND: Regular breakfast consumption has several health benefits. However, breakfast skipping is common among adolescents, in particular among those with a low socioeconomic background. The aims of the study were to explore individual and home environmental correlates of breakfast consumption, and to assess their potential mediating role in the association between parental education and breakfast consumption. METHODS: A cross-sectional study including 706 adolescents with a mean age of 13...
February 23, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28226192/carbazole-linked-nir-aza-bodipy-dyes-as-triplet-sensitizers-and-photoacoustic-contrast-agents-for-deep-tissue-imaging
#11
Nagaiyan Sekar, Ramaiah D, Yogesh Gawale, Adarsh N, Joseph J, M Pramanik, S K Kalva
Four novel N-ethylcarbazole linked aza-BODIPY dyes (8a-b and 9a-b) were synthesized and characterized. The presence of N-ethylcarbazole moiety shifts their absorption and fluorescence spectra to the near-infrared region, ca. 650-730 nm, of electromagnetic spectra. These dyes possess strong molar absorptivity in the range of 3-4 x 104 M-1cm-1 with low fluorescence quantum yields. The triplet excited state as well as singlet oxygen generation of these dyes were enhanced upon iodination at the core position. The core iodinated dyes 9a-b showed excellent triplet quantum yield of ca...
February 22, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28226183/development-of-an-acceptable-and-feasible-self-management-group-for-children-young-people-and-families-living-with-type-1-diabetes
#12
R A Cai, R I G Holt, L Casdagli, R M Viner, R Thompson, K Barnard, D Christie
AIMS: This study developed an acceptable and feasible self-management intervention that addresses the self-identified needs of children and young people with Type 1 diabetes and their parents. METHODS: Phase 1 reviewed previous interventions and interviewed the clinical team, young people and families. Phase 2 ran three age-matched focus groups with 11 families of children aged 8-16 years. Feedback was used to modify the workshop. Phase 3 evaluated feasibility of delivery, as well as the effects on metabolic control, quality of life and fear of hypoglycaemia, measured at baseline and 1-3 months post intervention...
February 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28224099/using-quality-improvement-methods-to-increase-use-of-pain-prevention-strategies-for-childhood-vaccination
#13
Jennifer Verrill Schurman, Amanda D Deacy, Rebecca J Johnson, Jolynn Parker, Kristi Williams, Dustin Wallace, Mark Connelly, Lynn Anson, Kevin Mroczka
AIM: To increase evidence-based pain prevention strategy use during routine vaccinations in a pediatric primary care clinic using quality improvement methodology. METHODS: Specific intervention strategies (i.e., comfort positioning, nonnutritive sucking and sucrose analgesia, distraction) were identified, selected and introduced in three waves, using a Plan-Do-Study-Act framework. System-wide change was measured from baseline to post-intervention by: (1) percent of vaccination visits during which an evidence-based pain prevention strategy was reported as being used; and (2) caregiver satisfaction ratings following the visit...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28223732/effects-of-sex-and-generation-on-hepatitis-b-viral-load-in-families-with-hepatocellular-carcinoma
#14
Ai-Ru Hsieh, Cathy Sj Fann, Chau-Ting Yeh, Hung-Chun Lin, Shy-Yi Wan, Yi-Cheng Chen, Chia-Lin Hsu, Jennifer Tai, Shi-Ming Lin, Dar-In Tai
AIM: To explore factors associated with persistent hepatitis B virus (HBV) infection in a cohort of hepatocellular carcinoma (HCC)-affected families and then investigate factors that correlate with individual viral load among hepatitis B surface antigen (HBsAg)-positive relatives. METHODS: We evaluated non-genetic factors associated with HBV replication in relatives of patients with HCC. Relatives of 355 HCC cases were interviewed using a structured questionnaire...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223426/resistance-mechanism-against-trastuzumab-in-her2-positive-cancer-cells-and-its-negation-by-src-inhibition
#15
Mei Hua Jin, Ah-Rong Nam, Ji Eun Park, Ju-Hee Bang, Yung-Jue Bang, Do-Youn Oh
Trastuzumab in combination with chemotherapy is the standard of care for patients with human epidermal growth factor receptor 2 (HER2)-positive breast and gastric cancers. Several resistance mechanisms against anti-HER2 therapy have been proposed. Src activation has been suggested to be responsible for the resistance of HER2-positive breast cancer. In our study, we generated four trastuzumab-resistant (HR) cancer cell lines from HER2-amplified gastric and biliary tract cancer cell lines (SNU-216, NCI-N87, SNU-2670, and SNU-2773)...
February 21, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28222722/a-longitudinal-study-on-determinants-of-hpv-vaccination-uptake-in-parents-guardians-from-different-ethnic-backgrounds-in-amsterdam-the-netherlands
#16
Catharina J Alberts, Maarten F Schim van der Loeff, Yvonne Hazeveld, Hester E de Melker, Marcel F van der Wal, Astrid Nielen, Fatima El Fakiri, Maria Prins, Theo G W M Paulussen
BACKGROUND: Human papillomavirus (HPV) vaccination coverage in the Netherlands is low (~60%) compared to other childhood vaccinations (>90%), and even lower among ethnic minorities. The aim of this study was to explore the possible impact of ethnicity on the determinants of both HPV vaccination intention and HPV vaccination uptake among parents/guardians having a daughter that is invited for the HPV vaccination. METHODS: In February 2014, parents/guardians living in Amsterdam were invited to complete a questionnaire about social-psychological determinants of their decision making process regarding the HPV vaccination of their daughter and socio-demographic characteristics...
February 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28222331/the-moro-reaction-more-than-a-reflex-a-ritualized-behavior-of-nonverbal-communication
#17
Pierre V Rousseau, Florence Matton, Renaud Lecuyer, Willy Lahaye
OBJECTIVE: To propose a phylogenetic significance to the Moro reflex which remains unexplained since its publication in 1918 because both hands are free at the end of the gesture. METHOD: Among the 75 videos of healthy term newborns we have filmed in a research project on antenatal education to parenthood, we describe a sequence that clearly showed the successive movements of the Moro reflex and we report the occurrence of this reflex in the videos that were recorded from Time 0 of birth defined as the moment that lies between the birth of the thorax and the pelvis of the infant...
February 18, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28222101/costs-and-effects-of-a-state-wide-health-promotion-program-in-primary-schools-in-germany-the-baden-w%C3%A3-rttemberg-study-a-cluster-randomized-controlled-trial
#18
Dorothea Kesztyüs, Romy Lauer, Tibor Kesztyüs, Reinhold Kilian, Jürgen M Steinacker
AIM: To evaluate the cost-effectiveness of the state-wide implementation of the health promotion program "Join the Healthy Boat" in primary schools in Germany. METHODS: Cluster-randomized intervention trial with wait-list control group. Anthropometric data of 1733 participating children (7.1 ± 0.6 years) were taken by trained staff before and after a one year intervention period in the academic year 2010/11. Parents provided information about the health status, and the health behaviour of their children and themselves, parental anthropometrics, and socio-economic background variables...
2017: PloS One
https://www.readbyqxmd.com/read/28221731/identifying-a-conceptual-shift-in-child-and-adolescent-reported-treatment-decision-making-having-a-say-as-i-need-at-this-time
#19
Katherine Patterson Kelly, Catriona Mowbray, Kimberly Pyke-Grimm, Pamela S Hinds
BACKGROUND: Professional organizations and governments recommend child and adolescent involvement in cancer treatment decision making (TDM) despite minimal evidence that children prefer involvement, how best to include them, and the result of doing so. PROCEDURE: Using descriptive qualitative research methods, we interviewed 20 children ages 9-17 years about their TDM preferences and experiences. We shifted our conceptualizations as findings emerged about how children with cancer viewed their decisional experiences...
April 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28221066/the-power-and-the-pain-of-adolescents-digital-communication-cyber-victimization-and-the-perils-of-lurking
#20
Marion K Underwood, Samuel E Ehrenreich
Many adolescents are heavily engaged with social media and text messaging (George & Odgers, 2015; Lenhart, 2015), yet few psychologists have studied what digital communication means for adolescents' relationships and adjustment. This article proposes that psychologists should embrace the careful study of adolescents' digital communication. We discuss theoretical frameworks for understanding adolescents' involvement with social media, present less widely recognized perils of intense involvement with social media, and highlight positive features of digital communication...
February 2017: American Psychologist
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