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Vitamin b complex

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https://www.readbyqxmd.com/read/29769494/clinical-profile-and-outcome-of-peripartum-cardiomyopathy-a-study-in-a-tertiary-cardiac-hospital-of-bangladesh
#1
N Fatema, S K Banerjee, C M Ahmed, A A Habib, F Rahman, S A Ahsan, H Hoque, R C Debnath, S Hashem, J Arzu
This study was done to evaluate the clinical profile, management and to analysis of pregnancy outcomes of peripartum cardiomyopathy pregnant women. Follow up was done after treatment and to see the prognosis. All patients admitted with peripartum cardiomyopathy from July 2009 to June 2014 in the department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh were considered for this observational study. Seventy two (72) women were evaluated. Primi-paras are 28 (39%) of the total study population...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29754112/mr1-antigen-presentation-to-mait-cells-new-ligands-diverse-pathways
#2
REVIEW
Hamish Eg McWilliam, Jose A Villadangos
The major histocompatibility complex class I-related molecule MR1 is the only antigen (Ag) presenting molecule that captures and displays vitamin B-derived metabolites that are unique to a wide array of microbes. Presentation of these metabolite Ag at the cell surface activates mucosal-associated invariant T (MAIT) cells, a highly abundant innate-like T cell population, and represents a recently-described mechanism used by the mammalian immune system to sense pathogenic or commensal microbes. Our understanding of the cell biology of how MR1 accomplishes this unique task is still evolving, but recent advances are allowing a general picture to emerge...
May 10, 2018: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29750879/dha-upregulates-fads2-expression-in-primary-cortical-astrocytes-exposed-to-vitamin-a
#3
B Dziedzic, D Bewicz-Binkowska, E Zgorzynska, D Stulczewski, L Wieteska, B Kaza, A Walczewska
The fads2 gene encoding delta6-desaturase, the rate-limiting enzyme in the LCPUFA biosynthesis is expressed in astrocytes. Dietary fatty acids, which cross the blood-brain barrier may regulate the transcription of lipogenic enzymes through activation of transcription factors such as peroxisome proliferator-activated receptors (PPARs). The PPARs form the transcription complex with retinoid X receptors (RXRs) that are activated by 9-cis retinol, a metabolite of vitamin A (VA). The study examines whether challenge of astrocytes with VA, prior 24-hour treatment with palmitic acid (PA), alpha-linolenic acid (ALA) or docosahexaenoic acid (DHA) has the effect on the FADS2 expression...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29736096/potential-anti-inflammatory-treatment-of-ischemic-heart-disease
#4
Enisa Hodzic
Introduction: Ischemic heart disease (IHD) is clinical manifestation of chronic inflammatory progressive pathological process of atherosclerosis in coronary arteries. IHD is the leading cause of morbidity and mortality in the world. The question is whether it is possible to improve and direct the therapeutic treatment of IHD patients in the treatment of the inflammatory process in the atherosclerotic leasions. Material and Methods: A prospective, comparative, analytica,clinically applicable, open-type study was performed...
April 2018: Medical Archives
https://www.readbyqxmd.com/read/29734420/the-complementary-effect-of-cholesterol-and-vitamin-e-preloaded-in-cyclodextrins-on-frozen-bovine-semen-motility-parameters-membrane-integrity-and-lipid-peroxidation
#5
A Khellouf, K Benhenia, S Fatami, M Iguer-Ouada
BACKGROUND: During cryopreservation sperm cells suffer from two major deleterious impacts: oxidative stress and cold shock. OBJECTIVE: To investigate in bovine species the benefit of cholesterol and vitamin E, both loaded in cyclodextrins, as a double protection against oxidative stress and cold shock. MATERIALS AND METHODS: Semen was collected from nine mature bulls using an artificial vagina and each ejaculate was split into four equal aliquots...
March 2018: Cryo Letters
https://www.readbyqxmd.com/read/29733902/paradoxical-effects-of-vitamin-c-in-chagas-disease
#6
J R P T Castanheira, R E P Castanho, H Rocha, C Pagliari, M I S Duarte, A L S Therezo, E F B Chagas, L P A Martins
Trypanosoma cruzi infection stimulates inflammatory mediators which cause oxidative stress, and the use of antioxidants can minimize the sequelae of Chagas disease. In order to evaluate the efficacy of vitamin C in minimizing oxidative damage in Chagas disease, we orally administered ascorbic acid to Swiss mice infected with 5.0 × 104 trypomastigote forms of T. cruzi QM2 strain. These animals were treated for 60 days to investigate the acute phase and 180 days for the chronic phase. During the acute phase, the animals in the infected and treated groups demonstrated lower parasitemia and inflammatory processes were seen in more mice in these groups, probably due to the higher concentration of nitric oxide, which led to the formation of peroxynitrite...
May 4, 2018: Parasitology International
https://www.readbyqxmd.com/read/29677539/fibromyalgia-and-nutrition-therapeutic-possibilities
#7
REVIEW
Geir Bjørklund, Maryam Dadar, Salvatore Chirumbolo, Jan Aaseth
Fibromyalgia (FM) is a complex chronic condition of unknown etiology, characterized by deep and widespread pain, sleep problems, cognitive impairment, fatigue, and other well-known functional symptoms. Recently, it has been proposed that an imbalance of nutritive components, including essential metal ions and vitamins, might play a critical role in the development of FM. Muscle pain has been associated with deficiencies in amino acids, magnesium, selenium, vitamins B and D, as well as with the harmful effects of heavy metals, such as mercury, cadmium, and lead...
April 17, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29672394/effects-of-vitamin-b-complex-and-vitamin-c-on-human-skin-cells-is-the-perceived-effect-measurable
#8
Julian-Dario Rembe, Carolin Fromm-Dornieden, Ewa Klara Stuermer
OBJECTIVE: Vitamins are essential for human health. In terms of local application for wound healing, vitamins' positive effect remains unclear. However, because of the regular appearance of nutritional deficiency in chronic wound patients, a favorable impact of locally applied vitamins can be hypothesized. METHODS: Vitamins B3, B5, B6, B7, B9, B10, B12, and C individually as well as different combinations of B vitamins were investigated regarding their ability to promote proliferation and migration of human skin fibroblasts and keratinocytes...
May 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29665762/effects-of-vitamin-b6-pyridoxine-and-a-b-complex-preparation-on-dreaming-and-sleep
#9
Denholm J Aspy, Natasha A Madden, Paul Delfabbro
Anecdotal evidence indicates that supplementation with vitamin B6 (pyridoxine) before bed can enhance dream vividness and recall. In a single pilot study, Ebben, Lequerica, and Spielman (2002) found that vitamin B6 had a dose-dependent effect of increasing scores on a composite measure of dream vividness, bizarreness, emotionality, and color. The present research replicated this study using a larger and more diverse sample of 100 participants from across Australia. We conducted a randomized, double-blind, placebo-controlled investigation of the effects on dreaming and sleep of ingesting 240 mg vitamin B6 (pyridoxine hydrochloride) before bed for five consecutive days...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29568330/antioxidant-effects-of-vitamins-in-type-2-diabetes-a-meta-analysis-of-randomized-controlled-trials
#10
Maria E Balbi, Fernanda S Tonin, Antonio M Mendes, Helena H Borba, Astrid Wiens, Fernando Fernandez-Llimos, Roberto Pontarolo
Background: Vitamins are essential micronutrients with antioxidant potential that may provide a complementary treatment for patients with chronic diseases. Our aim was to assess the effect of vitamin supplementation on the antioxidant status and glycemic index of type 2 diabetes mellitus patients. Methods: We performed a systematic review with meta-analyses. Electronic searches were conducted in PubMed, Scopus, and Web of Science (December 2017). Randomized controlled trials evaluating the effect of any vitamin or vitamin complex supplementation on antioxidant status as primary outcome were included...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29564464/vitamin-e-based-glycoside-amphiphiles-for-membrane-protein-structural-studies
#11
Muhammad Ehsan, Yang Du, Iago Molist, Alpay B Seven, Parameswaran Hariharan, Jonas S Mortensen, Lubna Ghani, Claus J Loland, Georgios Skiniotis, Lan Guan, Bernadette Byrne, Brian K Kobilka, Pil Seok Chae
Membrane proteins play critical roles in a variety of cellular processes. For a detailed molecular level understanding of their biological functions and roles in disease, it is necessary to extract them from the native membranes. While the amphipathic nature of these bio-macromolecules presents technical challenges, amphiphilic assistants such as detergents serve as useful tools for membrane protein structural and functional studies. Conventional detergents are limited in their ability to maintain the structural integrity of membrane proteins and thus it is essential to develop novel agents with enhanced properties...
March 22, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29550108/l-carnitine-and-vitamin-b-complex-for-the-treatment-of-pegasparaginase-induced-hyperbilirubinemia
#12
Caitlin R Rausch, Shilpa Paul, Kayleigh R Marx, Elias Jabbour, Naveen Pemmaraju, Alessandra Ferrajoli, Hagop Kantarjian
No abstract text is available yet for this article.
February 26, 2018: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/29540175/complex-genetic-architecture-in-severe-hypobetalipoproteinemia
#13
Linda R Wang, Adam D McIntyre, Robert A Hegele
BACKGROUND: Abetalipoproteinemia and homozygous hypobetalipoproteinemia are classical Mendelian autosomal recessive and co-dominant conditions, respectively, which are phenotypically similar and are usually caused by bi-allelic mutations in MTTP and APOB genes, respectively. Instances of more complex patterns of genomic variants resulting in this distinct phenotype have not been reported. METHODS: A 43 year-old male had a longstanding severe deficiency of apolipoprotein (apo) B-containing lipoproteins and circulating fat soluble vitamins consistent with either abetalipoproteinemia or homozygous familial hypobetalipoproteinemia (FHBL)...
March 14, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29528574/prevalence-of-vitamin-d-deficiency-in-adult-patients-with-systemic-lupus-erythematosus-in-kingdom-of-bahrain
#14
Eman Farid, Ahmed A Jaradat, Ola Al-Segai, Adla B Hassan
Vitamin D deficiency (VDD) has been implicated as an important factor in the development or aggravation of systemic lupus erythematous (SLE). Patients with SLE are especially prone to the development of VDD due to the nature of their illness and avoidance of sun exposure. The prevalence of VD status in Bahraini patients with SLE has not been studied. Our aim is to study the prevalence of VDD in Bahraini cohort with SLE. Fifty-eight Bahraini patients with SLE were included retrospectively in this study. Most of the patients were females 50/58...
June 2017: Egyptian Journal of Immunology
https://www.readbyqxmd.com/read/29509296/vitamin-b-complex-mitigates-cardiac-dysfunction-in-high-methionine-diet-induced-hyperhomocysteinemia
#15
Jovana Jeremic, Tamara Nikolic Turnic, Vladimir Zivkovic, Nevena Jeremic, Isidora Milosavljevic, Ivan Srejovic, Radmila Obrenovic, Snezana Jancic, Milena Rakocevic, Stevan Matic, Dragan Djuric, Vladimir Jakovljevic
This research is designed to test the hypothesis that elevated homocysteine (Hcy) levels in vivo, caused by a deficit in vitamin B complex, promote changes in cardiac function and redox status that lead to heart failure. In order to conduct the study, we used adult male Wistar albino rats (n = 30; 4 weeks old; 100 ± 15 g body weight). Hyperhomocysteinaemia (HHcy) in these animals was achieved by dietary manipulation. For 4 weeks, the animals were fed with a standard rodent chow (control, CF), a diet enriched in methionine with no deficiency in B vitamins (i...
March 6, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29508414/reduced-vitamin-d-receptor-vdr-expression-and-plasma-vitamin-d-levels-are-associated-with-aging-related-prostate-lesions
#16
Gabriel H Campolina-Silva, Bruna T Maria, Germán A B Mahecha, Cleida A Oliveira
BACKGROUND: Protective roles have been proposed for vitamin D in prostate cancer, which has the advanced age as the major risk factor. However, little is known about the expression of the vitamin D receptor (VDR) in the aging prostate and its association with the development of epithelial lesions that affect tissue homeostasis and may precede prostate tumors. METHODS: VDR expression in the prostatic complex of young adults to senile Wistar rats, a natural model to study age-related prostatic disorders, was evaluated by immunohistochemical, Western blotting, and image-assisted analyzes...
May 2018: Prostate
https://www.readbyqxmd.com/read/29507746/anti-oxidant-mediated-normalisation-of-raised-intracellular-cytokines-in-patients-with-reproductive-failure
#17
Kevin Marron, John F Kennedy, Conor Harrity
Background: Raised intracellular cytokine ratios (CKR) are proposed as a significant risk factor for adverse reproductive outcome. An elevated cytokine ratio, such as between TNFa and/or IFNg to IL-10 is associated with recurrent miscarriage (RM). The use of pharmacological immunomodulators such as TNFα inhibitors in these patients is controversial and not generally recommended due to a lack of conclusive data supporting their use. We evaluated whether the use of anti-oxidants/dietary supplements as an alternative could positively influence CKR's in ART patients...
2018: Fertility Research and Practice
https://www.readbyqxmd.com/read/29480570/evaluating-the-durability-of-uhmwpe-biomaterials-used-for-articulating-surfaces-of-joint-arthroplasty-using-delamination-tests
#18
Hideyuki Sakoda, Yuta Osaka, Keita Uetsuki, Yoshihiro Okamoto, Yuji Haishima
Ultra-high molecular weight polyethylene (UHMWPE) is the most popular material used for the articulating surface of joint replacements. Delamination is a common fatigue-related failure mode in UHMWPE components; however, the relationship between delamination resistance and fatigue crack growth has not been reported. Here, the delamination resistance of contemporary UHMWPE materials, including highly cross-linked UHMWPE (HXLPE), vitamin E blended UHMWPE (VEPE), and vitamin E blended HXLPE (VEXLPE), was measured to verify a previously proposed accelerated test method using a U-shaped sliding motion; the results were compared with those of fatigue crack growth tests...
February 26, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29464546/gene-diet-related-factors-of-hyperglycaemia-in-postmenopausal-women
#19
Bogna Grygiel-Górniak, Elżbieta Kaczmarek, Maria Mosor, Juliusz Przysławski, Jerzy Nowak
As ageing and increased body fat are the signs of insulin resistance, we have studied whether the presence of Pro12Ala and C1431T of peroxisome proliferator-activated receptor gamma 2 gene and Trp64Arg of beta 3-adrenergic receptor gene may predispose to the hyperglycaemia development in postmenopausal women, who have never undergone hypoglycaemic treatment. The distributions of selected allele and genotype frequencies were determined by the PCR-RFLP method in normo- and hyperglycaemic, who have never been diagnosed and treated for diabetes mellitus were measured...
May 2018: Journal of Applied Genetics
https://www.readbyqxmd.com/read/29460903/-the-efficacy-of-cocarnit-in-diabetic-neuropathy
#20
S V Kotov, E V Isakova, V Yu Leidvoll, Yu A Belova, T V Volchenkova, A V Borodin, V A Shvedov
AIM: To study the efficacy of the complex therapy, including cocarnit (group B vitamins, triphosadenine and nicotinamide), of diabetic neuropathy. MATERIAL AND METHODS: Forty-one patients with diabetes mellitus type 2 and distal symmetric sensorimotor polyneuropathy were examined. Patients were divided into 2 groups. Patients of the main group (n=26) received complex therapy, including cocarnit, and patients of the comparison group (n=15) received standard treatment...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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