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Subarachnoid hemorrhage

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https://www.readbyqxmd.com/read/29792042/imaging-predictors-of-outcome-in-acute-spontaneous-subarachnoid-hemorrhage-a-review-of-the-literature
#1
Isabel Fragata, Patrícia Canhão
Spontaneous subarachnoid hemorrhage (SAH) accounts for about 5% of strokes, but has a very high morbidity and mortality. Many survivors are left with important cognitive impairment and are severely incapacitated. Prediction of complications such as vasospasm and delayed cerebral ischemia, and of clinical outcome after SAH, is challenging. Imaging studies are essential in the initial evaluation of SAH patients and are increasingly relevant in assessing for complications and prognosis. In this article, we reviewed the role of imaging studies in evaluating early brain injury and predicting complications as well as clinical and neuropsychological prognosis after acute SAH...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29791584/risk-factors-for-early-onset-ventilator-associated-pneumonia-in-aneurysmal-subarachnoid-hemorrhage-patients
#2
J B Cui, Q Q Chen, T T Liu, S J Li
This study aimed to investigate the risk factors related to ventilator-acquired pneumonia (VAP) in aneurysmal subarachnoid hemorrhage (SAH) patients. From January 2011 to December 2015, a single-center retrospective study including 200 SAH patients requiring mechanical ventilation (MV) ≥48 h was performed. The clinical data of these patients were collected and analyzed. The age range of the patients were 41-63 and 72 (36%) were male. The Glasgow coma scale score range was 5-15 and the Simplified Acute Physiology Score II range was 31-52...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29790685/f2-isoprostanes-and-f4-neuroprostanes-as-markers-of-intracranial-aneurysm-development
#3
Anna Syta-Krzyżanowska, Iwona Jarocka-Karpowicz, Jan Kochanowicz, Grzegorz Turek, Robert Rutkowski, Krzysztof Gorbacz, Zenon Mariak, Elżbieta Skrzydlewska
BACKGROUND: Intracranial aneurysms are common, occurring in about 1-2% of the population. Saccular aneurysm is a pouch-like pathological dilatation of an intracranial artery that develops when the cerebral artery wall becomes too weak to resist hemodynamic pressure and distends. OBJECTIVES: The aim of this study was to determine whether the development of intracranial aneurysms and subarachnoid hemorrhage (SAH) affects neuronal phospholipid metabolism, and what influence different invasive treatments have on brain free radical phospholipid metabolism...
April 24, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29789872/endovascular-thrombectomy-for-large-vessel-occlusion-strokes-with-preexisting-intracranial-aneurysms
#4
Tengfei Zhou, Tianxiao Li, Liangfu Zhu, Ziliang Wang, Weixing Bai, Jiangyu Xue, Guang Feng
OBJECTIVE: This study aimed to investigate the safety of endovascular thrombectomy in acute ischemic stroke with preexisting intracranial aneurysms. METHODS: Patients with acute ischemic stroke due to large-artery occlusion combined with intracranial aneurysms, who received endovascular treatment, were analyzed retrospectively, and the procedure-related data were recorded. RESULTS: Among the 124 patients who suffered acute large-artery occlusion and received endovascular recanalization therapy, intracranial aneurysms were found in seven patients (5...
May 22, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29789216/the-clinical-presentation-and-collateral-pathway-development-of-congenital-absence-of-the-internal-carotid-artery
#5
Peng Zhang, Zheng Wang, Feng-Xia Yu, Han Lv, Xue-Huan Liu, Wei-Hua Feng, Jun Ma, Zheng-Han Yang, Zhen-Chang Wang
OBJECTIVE: The objective of this study was to investigate the clinical presentation, risks, and collateral pathway development of the congenital absence of the internal carotid artery (ICA). METHODS: Sixty-four patients (10 new patients and 54 patients from the relevant literature) were studied. Data on demographic, clinical, and radiologic features were collected, followed by an analysis of the risks associated with ICA agenesis. RESULTS: There were 31 male and 33 female patients whose ages ranged from 5 months to 75 years, with a mean age of 31...
May 19, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29789199/survival-after-in-hospital-cardiac-arrest-among-cerebrovascular-disease-patients
#6
REVIEW
Corey R Fehnel, Alissa Trepman, Dale Steele, Muhib A Khan, Brian Silver, Susan L Mitchell
Stroke is a leading cause of death and disability, and while preferences for cardiopulmonary resuscitation (CPR) are frequently discussed, there is limited evidence detailing outcomes after CPR among acute cerebrovascular neurology (inclusive of stroke, subarachnoid hemorrhage (SAH)) patients. Systematic review and meta-analysis of PubMed and Cochrane libraries from January 1990 to December 2016 was conducted among stroke patients undergoing in-hospital CPR. Primary data from studies meeting inclusion criteria at two levels were extracted: 1) studies reporting survival to hospital discharge after CPR with cerebrovascular primary admitting diagnosis, and 2) studies reporting survival to hospital discharge after CPR with cerebrovascular comorbidity...
May 19, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29785667/cerebral-autoregulation-in-stroke
#7
REVIEW
Pedro Castro, Elsa Azevedo, Farzaneh Sorond
PURPOSE OF REVIEW: Cerebral autoregulation (CA) is a mechanism that maintains cerebral blood flow constant despite fluctuations in systemic arterial blood pressure. This review will focus on recent studies that measured CA non-invasively in acute cerebrovascular events, a feature unique to the transcranial Doppler ultrasound. We will summarize the rationale for CA assessment in acute cerebrovascular disorders and specifically evaluate the existing data on the value of CA measures in relation to clinical severity, guiding management decisions, and prognostication...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29784726/teaching-neuroimages-convexal-subarachnoid-hemorrhage-accompanied-by-transient-global-amnesia
#8
Markus Beitzke, Christian Enzinger, Franz Fazekas
No abstract text is available yet for this article.
May 22, 2018: Neurology
https://www.readbyqxmd.com/read/29783859/impact-of-early-versus-late-intravenous-followed-by-oral-nimodipine-treatment-on-the-occurrence-of-delayed-cerebral-ischemia-among-patients-with-aneurysm-subarachnoid-hemorrhage
#9
Tipada Samseethong, Thanarat Suansanae, Kullapat Veerasarn, Anusak Liengudom, Chuthamanee Suthisisang
BACKGROUND: Guidelines for aneurysm subarachnoid hemorrhage (aSAH) management recommend treatment with nimodipine to all patients to reduce delayed cerebral ischemia (DCI) and poor clinical outcome. However, it did not give the most beneficial time to start therapy and route of administration. OBJECTIVES: To compare the DCI occurrence and clinical outcome among aSAH patients who received nimodipine treatment at different times. METHODS: A retrospective cohort study was conducted by collecting data from medical chart reviews between August 30, 2010, and October 31, 2015, at Prasart Neurological Institute, Thailand...
May 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29781055/psychosocial-comorbidities-related-to-return-to-work-rates-following-aneurysmal-subarachnoid-hemorrhage
#10
Eleanor R Turi, Yvette Conley, Elizabeth Crago, Paula Sherwood, Samuel M Poloyac, Dianxu Ren, Ansley G Stanfill
Purpose Ability to return to work (RTW) after stroke has been shown to have positive psychosocial benefits on survivors. Although one-fifth of aneurysmal subarachnoid hemorrhage (aSAH) survivors suffer from poor psychosocial outcomes, the relationship between such outcomes and RTW post-stroke is not clear. This project explores the relationship between age, gender, race, marital status, anxiety and depression and RTW 3 and 12 months post-aSAH. Methods Demographic and clinical variables were collected from the electronic medical record at the time of aSAH admission...
May 21, 2018: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/29780231/predictors-of-shunt-dependent-hydrocephalus-following-aneurysmal-subarachnoid-hemorrhage-a-pilot-study-in-a-single-egyptian-institute
#11
Hashem M Aboul-Ela, Ahmed M Salah El-Din, Ahmed A Zaater, Mohamed Shehab, Ossama A El Shahawy
Background: Acute hydrocephalus can cause neurological deterioration after aneurysmal subarachnoid hemorrhage (aSAH). Predicting which patient would require shunting is challenging. Methods: This prospective study was conducted upon twenty patients who suffered acute hydrocephalus due to subarachnoid hemorrhage of ruptured aneurysms. Surgical or non-surgical management of hydrocephalus was conducted. Glasgow Coma scale (GCS) was assessed, and hydrocephalus was graded by bicaudate index...
2018: The Egyptian journal of neurology, psychiatry and neurosurgery
https://www.readbyqxmd.com/read/29778996/stent-and-flow-diverter-assisted-treatment-of-acutely-ruptured-brain-aneurysms
#12
José E Cohen, J Moshe Gomori, Ronen R Leker, Sergey Spektor, Hosni Abu El Hassan, Eyal Itshayek
OBJECTIVE: We present our experience with stent techniques in the management of acutely ruptured aneurysms, focusing on aneurysm occlusion rates, intraprocedural complications, and late outcomes. METHODS: We retrospectively reviewed the clinical records of patients treated by stent techniques during the early acute phase of aneurysmal rupture, from June 2011 to June 2016. Patients who underwent stenting for the management of unruptured aneurysms, or in a delayed fashion for a ruptured lesion, were excluded...
May 19, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29778597/microsurgical-clipping-of-ruptured-anterosuperior-projecting-anterior-communicating-artery-aneurysms-how-i-do-it
#13
Feng Xu, Nicholas C Bambakidis
In anterosuperior-projecting anterior communicating artery (ACoA) aneurysms, the aneurysm dome usually adheres to one or both proximal A2 segment, which may present technical difficulties. This video demonstrates microsurgical clipping of a ruptured anterosuperior-projecting AComA aneurysm. A 52-year-old male presented with a Hunt-Hess grade II subarachnoid hemorrhage (SAH). Computed tomography showed SAH in the basal cisterns, sylvian and interhemispheric fissures. Angiography demonstrated a wide-necked AComA aneurysm projecting anterosuperiorly...
May 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29778299/cerebral-perfusion-pressure-threshold-to-prevent-delayed-cerebral-ischemia-after-aneurysmal-subarachnoid-hemorrhage
#14
Jiawei Cai, Wenhua Fang, Fuxiang Chen, Zhangya Lin, Yuanxiang Lin, Lianghong Yu, Peisen Yao, Dezhi Kang
OBJECTIVE: To seek a cerebral perfusion pressure (CPP) threshold that can reduce the occurrence of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). METHODS: We analyzed the clinical data of patients with the diagnosis of aSAH and underwent CPP monitoring in our department from February 2014 to December 2015. CPP was divided into four specified thresholds by every 10 mmHg increments, which were from 50 mmHg to 80 mmHg. The totally time ratio of CPP below each threshold was calculated...
May 16, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29777889/endovascular-management-of-a-ruptured-basilar-perforator-artery-aneurysm-associated-with-a-pontine-arteriovenous-malformation-a-case-report-and-review-of-the-literature
#15
Joseph Lockwood, Tyler Scullen, Mansour Mathkour, Ascher Kaufmann, Ricky Medel, Aaron S Dumont, Peter S Amenta
BACKGROUND: Arteriovenous malformation (AVM)-associated aneurysms are common, being reported in 15% of cases. In regards to ruptured posterior fossa AVMs, associated aneurysms are present in 48% of cases and are the etiology of the bleed in 37%. We present a 75 year-old female who presented with a subarachnoid hemorrhage (SAH) secondary to a ruptured aneurysm arising from a flow-related basilar perforator artery feeder of an anterior pontine AVM. We report the successful treatment of the aneurysm with coil embolization...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29776733/exploratory-study-of-the-course-of-posttraumatic-stress-disorder-after-aneurysmal-subarachnoid-hemorrhage
#16
Irene M C Huenges Wajer, Anouk R Smits, Gabriel J E Rinkel, Martine J E van Zandvoort, Leoniek Wijngaards-de Meij, Johanna M A Visser-Meily
OBJECTIVE: Posttraumatic stress disorder (PTSD) occurs often in aneurysmal subarachnoid hemorrhage (aSAH) survivors, but how PTSD develops over time post-aSAH is still unclear. We examined the course of PTSD symptoms during the first year after aSAH. METHOD: In this prospective cohort study, the Impact of Event Scale (IES) was applied in 128 patients 3, 6 and 12 months after aSAH. Multilevel modelling was used to assess changes in levels of PTSD symptoms over time and to explore if demographic characteristics, aSAH characteristics, level of education, cognitive functioning and neuroticism are associated to the course of PTSD symptoms...
May 9, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29775770/treatment-of-ruptured-vertebral-artery-dissection-and-abdominal-hemorrhage-associated-with-segmental-arterial-mediolysis-using-endovascular-coil-embolization-va-dissection-associated-with-sam
#17
Taiki Isaji, Tomotaka Ohshima, Sigeru Miyachi, Naoki Matsuo, Reo Kawaguchi, Masakazu Takayasu
BACKGROUND: Segmental arterial mediolysis is a rare disease characterized by idiopathic noninflammatory vasculopathy involving small to medium arteries. Here, we report a case of ruptured cerebral and abdominal aneurysms, which were successfully treated using emergency endovascular coil embolization. CASE DESCRIPTION: A 45-year-old male suffered subarachnoid hemorrhage caused by the rupture of the right vertebral artery dissecting aneurysm, which was treated using emergency endovascular coiling...
May 15, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29773103/-curcumin-alleviates-early-brain-injury-following-subarachnoid-hemorrhage-in-rats-by-inhibiting-jnk-c-jun-signal-pathway
#18
Xia Li, Ji Zhu
Objective To investigate the inhibitory effect of curcumin on early brain injury following subarachnoid hemorrhage (SAH) by inhibiting JNK/ c-Jun signal pathway. Methods Sixty adult male SD rats were randomly divided into four groups: sham operation group (sham group), SAH group, SAH group treated with 100 mg/(kg.d) curcumin and SAH group treated with 200 mg/(kg.d) curcumin, with 15 rats in each group. Endovascular puncture was used to induce SAH model. Nissl staining was used to test whether neurons were broken...
March 2018: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/29772479/adverse-lipid-profile-elevates-risk-for-subarachnoid-hemorrhage-a-prospective-population-based-cohort-study
#19
Joni Lindbohm, Miikka Korja, Pekka Jousilahti, Veikko Salomaa, Jaakko Kaprio
BACKGROUND AND AIMS: Studies report that both high and low total cholesterol (TC) elevates SAH risk. There are few prospective studies on high-density lipoproteins (HDL-C) and low-density lipoproteins (LDL-C), and apparently none concerns apolipoproteins A and B. We aimed to clarify the association between lipid profile and SAH risk. METHODS: The National FINRISK study provided risk-factor data recorded at enrolment between 1972 and 2007. During 1.52 million person-years of follow-up until 2014, 543 individuals suffered from incident hospitalized SAH or outside-hospital-fatal SAH...
May 5, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29771435/lncrna-meg3-participates-in-neuronal-cell-injury-induced-by-subarachnoid-hemorrhage-via-inhibiting-the-pi3k-akt-pathway
#20
Z Liang, Y-J Chi, G-Q Lin, L-F Xiao, G-L Su, L-M Yang
OBJECTIVE: To explore the effect of LncRNA MEG3 in the subarachnoid hemorrhage (SAH) and its underlying mechanism. PATIENTS AND METHODS: The expressions of lncRNA MEG3 in SAH patients and animal model were detected by quantitative real-time PCR (qRT-PCR). After LncRNA MEG3 was overexpressed in neurons by lentivirus, viability and apoptosis abilities were detected by cell counting kit-8 (CCK-8) assay, flow cytometry, and TUNEL assay, respectively. The apoptosis-related genes and Pi3k/Akt pathway-related proteins were further detected by a Western blot...
May 2018: European Review for Medical and Pharmacological Sciences
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