keyword
MENU ▼
Read by QxMD icon Read
search

Vitamin c

keyword
https://www.readbyqxmd.com/read/29454011/comparative-study-on-some-oxidative-stress-parameters-in-blood-of-vitiligo-patients-before-and-after-combined-therapy
#1
A Zheleva, G Nikolova, Y Karamalakova, E Hristakieva, R Lavcheva, V Gadjeva
Currently accepted that oxidative stress is a triggering event in the melanocytic destruction and is probably involved in the etiopathogenesis of vitiligo disease. Despite numerous investigations, contradictory results were reported about the levels of oxidative stress biomarkers measured in the skin and blood of vitiligo patients. By Electron Paramagnetic Resonance spectroscopy (EPR) and spectrophotometry, we have investigated and compared some oxidative stress biomarkers in the blood of vitiligo patients' before and after UVB Narrow Band 311 nm phototherapy combined with the antioxidant nutritional supplement containing - Vitamin C, Vitamin B1, L -Cysteine, Lipoic Acid, and polyunsaturated fatty acids...
February 14, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29453427/orthodox-religious-fasting-as-a-medical-nutrition-therapy-for-dyslipidemia-where-do-we-stand-and-how-far-can-we-go
#2
REVIEW
Theocharis Koufakis, Spyridon N Karras, Pantelis Zebekakis, Kalliopi Kotsa
Previous studies have reported inconclusive results regarding the effects of Orthodox religious fasting (OF) on common cardiovascular risk factors, including arterial hypertension and diabetes. Contrariwise, an optimal effect on dyslipidemia has been demonstrated and significant reductions in total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) concentrations, in Orthodox populations without comorbidities, have been consistently reported. This favorable effect on lipid homeostasis is probably facilitated by a broad lifestyle modification related to OF, extended beyond dietary habits...
February 16, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29453305/frequency-and-outcomes-of-reduced-dose-non-vitamin-k-antagonist-anticoagulants-results-from-orbit-af-ii-the-outcomes-registry-for-better-informed-treatment-of-atrial-fibrillation-ii
#3
Benjamin A Steinberg, Peter Shrader, Karen Pieper, Laine Thomas, Larry A Allen, Jack Ansell, Paul S Chan, Michael D Ezekowitz, Gregg C Fonarow, James V Freeman, Bernard J Gersh, Peter R Kowey, Kenneth W Mahaffey, Gerald V Naccarelli, James A Reiffel, Daniel E Singer, Eric D Peterson, Jonathan P Piccini
BACKGROUND: Non-vitamin K antagonist oral anticoagulants (NOACs) are indicated for stroke prevention in atrial fibrillation (AF) but require lower doses in certain patients. We sought to describe the frequency, appropriateness (according to Food and Drug Administration labeling), and outcomes of patients prescribed reduced doses of NOACs in community practice. METHODS AND RESULTS: We analyzed data from the ORBIT-AF II (The Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II) registry, a prospective, national, observational registry of AF patients...
February 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29452565/serum-vitamin-c-levels-modulate-the-lifespan-and-endoplasmic-reticulum-stress-response-pathways-in-mice-synthesizing-a-nonfunctional-mutant-wrn-protein
#4
Lucie Aumailley, Marie Julie Dubois, Tracy A Brennan, Chantal Garand, Eric R Paquet, Robert J Pignolo, André Marette, Michel Lebel
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase (WRN). Mice lacking part of the helicase domain of the WRN ortholog exhibit several phenotypic features of WS. In this study, we generated a Wrn mutant line that, like humans, relies entirely on dietary sources of vitamin C (ascorbate) to survive, by crossing them to mice that lack the gulonolactone oxidase enzyme required for ascorbate synthesis. In the presence of 0.01% ascorbate (w/v) in drinking water, double-mutant mice exhibited a severe reduction in lifespan, small size, sterility, osteopenia, and metabolic profiles different from wild-type (WT) mice...
February 8, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29452404/vitamin-e-and-vitamin-c-supplementation-improves-antioxidant-status-and-immune-function-in-oxidative-stressed-breeder-roosters-by-up-regulating-expression-of-gsh-px-gene
#5
Y N Min, Z Y Niu, T T Sun, Z P Wang, P X Jiao, B B Zi, P P Chen, D L Tian, F Z Liu
This study aimed to evaluate the effects of vitamin C and vitamin E on antioxidant capacity and immune function in oxidative-stressed breeder roosters. One hundred twenty 45-week-old Lveyang black-boned breeder roosters were randomly assigned to 5 dietary treatments, including negative control group (NC), positive control group (PC), and 3 trial groups, which were fed the diets containing 300 mg/kg VC, 200 mg/kg VE, or 300 mg/kg VC and 200 mg/kg VE (VC+VE). At 47 wk of age, the positive control and trial groups were subcutaneously injected 3 times every other d with dexamethasone (DEX) 4 mg/kg of body weight, the negative control group was injected with saline...
February 14, 2018: Poultry Science
https://www.readbyqxmd.com/read/29452375/1%C3%AE-hydroxycholecalciferol-improves-the-growth-performance-and-up-regulates-the-mrna-expression-of-vitamin-d-receptor-in-the-small-intestine-and-kidney-of-broiler-chickens
#6
J C Han, J G Wang, G H Chen, J L Zhang, N Zhang, H X Qu, Y Guo, Y F Yan, X J Yang
1α-Hydroxycholecalciferol (1α-OH-D3) is a vitamin D derivative. The objective of this study was to evaluate the effects of 1α-OH-D3 on the growth and the mRNA expression of vitamin D receptor (VDR) in the small intestine and kidney of chickens. A total of 240 males of one-day-old Ross 308 broilers was randomly assigned to 4 treatments with 5 replicates of 12 birds per replicate. Three levels of 1α-OH-D3 (1.25, 2.5, and 5 μg/kg) were added to a basal diet containing 0.50% calcium (Ca), 0.25% non-phytate phosphorus (NPP), and without supplemental cholecalciferol (vitamin D3)...
February 14, 2018: Poultry Science
https://www.readbyqxmd.com/read/29452159/cyp27a1-acts-on-the-pre-vitamin-d3-photoproduct-lumisterol-producing-biologically-active-hydroxy-metabolites
#7
Robert C Tuckey, Wei Li, Dejian Ma, Chloe Y S Cheng, Katie M Wang, Tae-Kang Kim, Saowanee Jeayeng, Andrzej T Slominski
Prolonged exposure of the skin to UV radiation causes previtamin D3, the initial photoproduct formed by opening of the B ring of 7-dehydrocholesterol, to undergo a second photochemical reaction where the B-ring is reformed giving lumisterol3 (L3), a stereoisomer of 7-dehydrocholesterol. L3 was believed to be an inactive photoproduct of excessive UV radiation whose formation prevents excessive vitamin D production. Recently, we reported that L3 is present in serum and that CYP11A1 can act on L3 producing monohydroxy- and dihydroxy-metabolites which inhibit skin cell proliferation similarly to 1α,25-dihydroxyvitamin D3...
February 13, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29452153/functionalization-of-nanodiamond-with-vitamin-e-tpgs-to-facilitate-oral-absorption-of-curcumin
#8
Bingchao Cheng, Hao Pan, Dandan Liu, Dongyang Li, Jinyu Li, Shihui Yu, Guoxin Tan, Weisan Pan
The purpose of this work was to develop a D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) decorated nanodiamond (ND) system loading water-insoluble curcumin (ND/CUR/TPGS) to improve the colloidal dispersity and oral bioavailability of the preparation. CUR was physically loaded into ND clusters, then TPGS was coated to the ND/CUR complex forming amorphous nanostructure on the interparticle nanocage of the ND substrate. The formulation of the nanocomplexes was optimized using response surface methodology, and the optimal ND/CUR/TPGS showed small particle size (196...
February 13, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29450585/effect-of-isolated-vitamin-d-supplementation-on-bone-turnover-markers-in-younger-postmenopausal-women-a-randomized-double-blind-placebo-controlled-trial
#9
J Nahas-Neto, L M Cangussu, C L Orsatti, F N Bueloni-Dias, P F Poloni, E B Schmitt, E A P Nahas
Vitamin D (VD) plays an important role in bone mineralization. The present study investigates the effect of VD supplementation alone on bone turnover markers in younger postmenopausal women. It has been shown that VD supplementation in postmenopausal women with hypovitaminosis D is associated with a reduction in bone turnover markers. PURPOSE: The purpose of this study is to evaluate the effect of VD supplementation alone on bone turnover markers in younger postmenopausal women. METHODS: In this double-blind, placebo-controlled trial, 160 women were randomized into the VD group (supplementation with 1000 IU of vitamin D3/day, orally; n = 80) or placebo group (n = 80)...
February 15, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29450200/nutritional-compositions-and-phytochemical-properties-of-the-edible-flowers-from-selected-zingiberaceae-found-in-thailand
#10
Apinya Rachkeeree, Kuttiga Kantadoung, Ratchuporn Suksathan, Ratchadawan Puangpradab, Paul Alexander Page, Sarana Rose Sommano
The nutritional compositions and phytochemical properties of eight edible flowers of the ginger family (Zingiberaceae) commonly found in Thailand are reported herein. The plant genera investigated were Zingiber (Ginger, Phlai Dam, Krathue), Hedychium (two morphological filament forms), Curcuma (Ao), Etlingera (Torch ginger), Amomum (Chi Kuk), and Alpinia (Galangal), which are eaten fresh or cooked as ingredients in the preparation of many Thai dishes. The proximate compositions (moisture, ash, fiber, protein, fat, and carbohydrate contents) varied among the different genera...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29449952/variations-of-dietary-intake-by-glycemic-status-and-hispanic-latino-heritage-in-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#11
Sarah S Casagrande, Daniela Sotres-Alvarez, Larissa Avilés-Santa, Matthew J O'Brien, Cristina Palacios, Cynthia M Pérez, Samantha A Reina, Xueyin Wang, Qibin Qi, Aida L Giachello, Rebeca A Espinoza Giacinto, Catherine C Cowie
Objective: A healthy diet is important for diabetes prevention and control; however, few studies have assessed dietary intake among US Hispanics/Latinos, a diverse population with a significant burden of diabetes. To address this gap in the literature, we determined intake of energy, macro/micronutrients, and vitamin supplements among Hispanics/Latinos by glycemic status and heritage. Research design and methods: Cross-sectional study of adults aged 18-74 years from the Hispanic Community Health Study/Study of Latinos (2008-2011) with complete baseline data on glycemic status and two 24-hour dietary recalls (n=13 089)...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/29448922/a-randomised-control-crossover-trial-of-a-theory-based-intervention-to-improve-sun-safe-and-healthy-behaviours-in-construction-workers-study-protocol
#12
Amanda Nioi, Charlotte Wendelboe-Nelson, Sue Cowan, Hilary Cowie, Shahzad Rashid, Peter Ritchie, Mark Cherrie, Terry C Lansdown, John W Cherrie
BACKGROUND: Exposure to sunlight can have both positive and negative health impacts. Excessive exposure to ultra-violet (UV) radiation from the sun can cause skin cancer, however insufficient exposure to sunlight has a detrimental effect on production of Vitamin D. In the construction industry there are onsite proactive behaviours for safety, but sun-safety remains a low priority. There is limited research on understanding the barriers to adopting sun-safe behaviours and the association this may have with Vitamin D production...
February 15, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29448554/conductive-adhesive-based-on-mussel-inspired-graphene-decoration-with-silver-nanoparticles
#13
Marcello Casa, Maria Sarno, Rosalba Liguori, Claudia Cirillo, Alfredo Rubino, Emanuele Bezzeccheri, Johan Liu, Paolo Ciambelli
Decoration with silver nanoparticles was obtained by coating graphene with a polydopamine layer, able to induce spontaneous metallic nanoparticles formation without any specific chemical interfacial modifier, neither using complex instrumentation. The choice of dopamine was inspired by the composition of adhesive proteins in mussels, related to their robust attach to solid surfaces. The synthesis procedure started from graphite and involved eco-friendly compounds, such as Vitamin C and glucose as reducing agent and water as reaction medium...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448090/uhplc-qtof-ms-analysis-of-bioactive-constituents-from-two-romanian-goji-lycium-barbarum-l-berries-cultivars-and-their-antioxidant-enzyme-inhibitory-and-real-time-cytotoxicological-evaluation
#14
Andrei Mocan, Cadmiel Moldovan, Gökhan Zengin, Onur Bender, Marcello Locatelli, Mario Simirgiotis, Arzu Atalay, Dan C Vodnar, Sascha Rohn, Gianina Crișan
Goji (Lycium barbarum L.) berries are emphasized as healthy food or are used widely as dietary supplements. In the present study, the antioxidant and enzyme inhibitory activities of berries extracts from two selected Romanian cultivars (cv. Erma and cv. Biglifeberry) have been evaluated. UHPLC-QTOF-MS analysis results revealed the presence of vitamin C and related compounds, phenolic acids, flavonoids, fatty acids (oxylipins), and spermidine derivatives. In particular, cv. Erma showed a strong tyrosinase-inhibitory effect, whereas cv...
February 12, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29447929/a-complex-systems-approach-to-cancer-prevention
#15
P W Jupp
Cancer incidence continues to be a major health problem possibly because cancer is a complex system comprising many agents that interact in a non-linear manner resulting in many possible outcomes. The degree of complexity of a cancer system could be vast involving multiple endogenous and exogenous agents interacting with the over 10 trillion cells comprising the body. It is hypothesized that the practical management of this complexity may be a key to cancer prevention and possibly treatment. But the management and resolution of such an immensely complex system is difficult and may require a multidisciplinary approach including physics, biology, biochemistry and medical science...
March 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29447824/central-xanthoma-of-the-mandible-associated-with-hyperlipidemia-a-rare-presentation
#16
John K Brooks, Behzad Mostoufi, Ahmed S Sultan, Zaid H Khoury, Jeffery B Price, John C Papadimitriou, John R Basile, Cinthia B Drachenberg, Rania H Younis
Xanthoma is a common, self-limiting cutaneous lesion of non-Langerhans cell, lipid-laden foamy histiocytes that is often concomitant with hyperlipidemia. The intraosseous counterpart is rarely encountered and typically presents as a painless, expansile osteolytic process in the context of hyperlipidemia or normolipidemia. Only a scant number of gnathic xanthomas have been reported in the otolaryngologic literature. We report the clinical, laboratory, radiographic, histopathologic, immunohistochemical, and ultrastructural studies of a mandibular lesion discovered in an asymptomatic 16-year-old male, and associated with 2 previously unreported comorbidities, namely hyperlipidemia and vitamin D deficiency...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447442/the-phenolic-group-of-%C3%AE-tocopherol-anchors-in-the-lipid-water-interface-of-fully-saturated-membranes
#17
Alessio Ausili, Alejandro Torrecillas, Ana M deGodos, Senena Corbalan-Garcia, Juan C Gomez-Fernandez
α-Tocopherol is considered to carry on a very important role as antioxidant of membranes and lipoproteins and other biological roles as membrane stabilizers and bioactive lipids. Given its essential role, it is very important to fully understand its location in the membrane. In this work, the vertical location of vitamin E in saturated membranes has been studied using biophysical techniques. Small- and wide-angle X-ray diffraction experiments show that α-tocopherol alters the water layer between bilayers in both DMPC and DPPC, indicating its proximity to this surface...
February 15, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29447191/euglena-extract-suppresses-adipocyte-differentiation-in-human-adipose-derived-stem-cells
#18
Ryota Sugimoto, Naoko Ishibashi-Ohgo, Kohei Atsuji, Yuko Miwa, Osamu Iwata, Ayaka Nakashima, Kengo Suzuki
Euglena gracilis Z (Euglena) is a unicellular, photosynthesizing, microscopic green alga. It contains several nutrients such as vitamins, minerals, and unsaturated fatty acids. In this study, to verify the potential role of Euglena consumption on human health and obesity, we evaluated the effect of Euglena on human adipose-derived stem cells. We prepared a Euglena extract and evaluated its effect on cell growth and lipid accumulation, and found that cell growth was promoted by the addition of the Euglena extract...
2018: PloS One
https://www.readbyqxmd.com/read/29447086/vitamin-d-down-regulates-the-expression-of-some-th17-cell-related-cytokines-key-inflammatory-chemokines-and-chemokine-receptors-in-experimental-autoimmune-encephalomyelitis
#19
Abdollah Jafarzadeh, Sayyed Vahab Azizi, Zahra Arabi, Rayhaneh Ahangar-Parvin, Marziyeh Mohammadi-Kordkhayli, Tiziana Larussa, Fariba Khatami, Maryam Nemati
OBJECTIVES: A spectrum of immunomodulatory properties was attributed to vitamin D (VD). Here, the VD effects on expression of some Th17 cell- related cytokines, chemokines and chemokine receptors were investigated in experimental autoimmune encephalomyelitis (EAE). METHODS: One group of C57BL/6 mice, considered as healthy group, was treated with phosphate buffered saline (PBS). EAE was induced in other three groups and treated from day +3 to +30 with PBS, olive oil (VD vehicle) or 200 ng of VD...
February 15, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29446079/dietary-intake-of-nutrients-involved-in-one-carbon-metabolism-and-risk-of-urothelial-cell-carcinoma-a-prospective-cohort-study
#20
Pierre-Antoine Dugué, Maree T Brinkman, Allison M Hodge, Julie K Bassett, Damien Bolton, Anthony Longano, John L Hopper, Melissa C Southey, Dallas R English, Roger L Milne, Graham G Giles
Nutrients involved in one-carbon metabolism may play a role in carcinogenesis through DNA replication, repair and methylation mechanisms. Most studies on urothelial cell carcinoma (UCC) have focused on folate. We sought to examine the association between B-group vitamins and methionine intake and UCC risk, overall and by subtype, and to test whether these associations are different for population subgroups whose nutritional status may be compromised. We followed participants in the Melbourne Collaborative Cohort Study (N=41,513) for over 20 years, and observed 500 UCC cases (89% originating in the bladder; superficial: 279, invasive: 221)...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
keyword
keyword
18759
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"